LT3167076T - Metodai ir produktai, skirti rnr transkripto variantų kiekybiniam įvertinimui - Google Patents

Metodai ir produktai, skirti rnr transkripto variantų kiekybiniam įvertinimui

Info

Publication number
LT3167076T
LT3167076T LTEPPCT/EP2015/065756T LT15065756T LT3167076T LT 3167076 T LT3167076 T LT 3167076T LT 15065756 T LT15065756 T LT 15065756T LT 3167076 T LT3167076 T LT 3167076T
Authority
LT
Lithuania
Prior art keywords
products
methods
rna transcript
transcript variants
quantifying rna
Prior art date
Application number
LTEPPCT/EP2015/065756T
Other languages
English (en)
Inventor
Lukas Paul
Petra KUBALA
Torsten Reda
Original Assignee
Lexogen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexogen Gmbh filed Critical Lexogen Gmbh
Publication of LT3167076T publication Critical patent/LT3167076T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6846—Common amplification features
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2545/00—Reactions characterised by their quantitative nature
    • C12Q2545/10—Reactions characterised by their quantitative nature the purpose being quantitative analysis
    • C12Q2545/113—Reactions characterised by their quantitative nature the purpose being quantitative analysis with an external standard/control, i.e. control reaction is separated from the test/target reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
LTEPPCT/EP2015/065756T 2014-07-09 2015-07-09 Metodai ir produktai, skirti rnr transkripto variantų kiekybiniam įvertinimui LT3167076T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14176417 2014-07-09
PCT/EP2015/065756 WO2016005524A1 (en) 2014-07-09 2015-07-09 Methods and products for quantifying rna transcript variants

Publications (1)

Publication Number Publication Date
LT3167076T true LT3167076T (lt) 2022-02-10

Family

ID=51224706

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2015/065756T LT3167076T (lt) 2014-07-09 2015-07-09 Metodai ir produktai, skirti rnr transkripto variantų kiekybiniam įvertinimui

Country Status (11)

Country Link
US (1) US10513726B2 (lt)
EP (1) EP3167076B1 (lt)
JP (3) JP6930910B2 (lt)
KR (1) KR102555447B1 (lt)
CN (1) CN106471134B (lt)
AU (1) AU2015286672B2 (lt)
CA (1) CA2954495C (lt)
DK (1) DK3167076T3 (lt)
HK (1) HK1231518A1 (lt)
LT (1) LT3167076T (lt)
WO (1) WO2016005524A1 (lt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2756098T (lt) 2011-09-16 2018-09-10 Lexogen Gmbh Nukleorūgščių molekulių bibliotekos sudarymo būdas
US10513726B2 (en) 2014-07-09 2019-12-24 Lexogen Gmbh Methods for controlled identification and/or quantification of transcript variants in one or more samples
CN106771194B (zh) * 2017-01-18 2018-07-20 青岛大学 一种检测病原微生物的方法
US10828330B2 (en) * 2017-02-22 2020-11-10 IO Bioscience, Inc. Nucleic acid constructs comprising gene editing multi-sites and uses thereof
SE541799C2 (en) * 2018-04-11 2019-12-17 David Yudovich Determination of frequency distribution of nucleotide sequence variants
CN110438234B (zh) * 2018-05-02 2023-05-26 宁夏农林科学院动物科学研究所 一种基于基因分型鉴定滩羊与非滩羊的方法
EP3666904A1 (en) 2018-12-14 2020-06-17 Lexogen GmbH Nucleic acid amplification and identification method
EP3901284A1 (en) * 2020-04-20 2021-10-27 BMBK Invest BV Construct, kit and method for sample tracking
KR20220000850A (ko) 2020-06-26 2022-01-04 숙명여자대학교산학협력단 비타민 b1의 보호 및 전달을 위한 장용성 조성물
KR20220000849A (ko) 2020-06-26 2022-01-04 숙명여자대학교산학협력단 사이클로덱스트린을 이용한 경구투여용 복합 조성물 및 이의 제조방법
WO2023086441A1 (en) * 2021-11-12 2023-05-19 Regents Of The University Of Minnesota Compositions and methods for transcriptional activation
US20240042057A1 (en) * 2022-05-13 2024-02-08 Ascidian Therapeutics, Inc. Abca4 trans-splicing molecules

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2593343B1 (fr) 1986-01-20 1988-03-25 Thomson Csf Matrice d'elements photosensibles et son procede de fabrication, procede de lecture associe, et application de cette matrice a la prise de vue d'images
WO2002072889A2 (en) * 2001-01-12 2002-09-19 Applera Corporation Methods and compositions for microarray control
CA2446531A1 (en) 2001-05-07 2002-11-14 Amersham Biosciences Corp Design of artificial genes for use as controls in gene expression analysis systems
US20040009512A1 (en) * 2002-05-02 2004-01-15 Manuel Ares Arrays for detection of products of mRNA splicing
EP1730162A4 (en) * 2004-03-11 2008-12-10 Us Gov Health & Human Serv ARTIFICIAL MUTATIONAL CHECKS FOR DIAGNOSTIC TESTS
EP2333104A1 (en) * 2009-12-11 2011-06-15 Lexogen GmbH RNA analytics method
US10513726B2 (en) 2014-07-09 2019-12-24 Lexogen Gmbh Methods for controlled identification and/or quantification of transcript variants in one or more samples

Also Published As

Publication number Publication date
JP6930910B2 (ja) 2021-09-01
WO2016005524A1 (en) 2016-01-14
CN106471134B (zh) 2021-11-12
CN106471134A (zh) 2017-03-01
EP3167076B1 (en) 2021-11-17
EP3167076A1 (en) 2017-05-17
JP2021153588A (ja) 2021-10-07
CA2954495C (en) 2024-03-05
KR20170028383A (ko) 2017-03-13
HK1231518A1 (zh) 2017-12-22
CA2954495A1 (en) 2016-01-14
US10513726B2 (en) 2019-12-24
JP2017525341A (ja) 2017-09-07
KR102555447B1 (ko) 2023-07-13
JP2020014478A (ja) 2020-01-30
AU2015286672A1 (en) 2016-12-15
AU2015286672B2 (en) 2021-12-02
DK3167076T3 (da) 2022-02-21
US20170321248A1 (en) 2017-11-09

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