HK1231518A1 - 用於定量 轉錄物變體的方法和產物 - Google Patents

用於定量 轉錄物變體的方法和產物

Info

Publication number
HK1231518A1
HK1231518A1 HK17105265.8A HK17105265A HK1231518A1 HK 1231518 A1 HK1231518 A1 HK 1231518A1 HK 17105265 A HK17105265 A HK 17105265A HK 1231518 A1 HK1231518 A1 HK 1231518A1
Authority
HK
Hong Kong
Prior art keywords
rna
products
methods
quantifying
transcript variants
Prior art date
Application number
HK17105265.8A
Other languages
English (en)
Inventor
．保羅
．庫巴拉
．萊達
Original Assignee
Lexogen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexogen Gmbh filed Critical Lexogen Gmbh
Publication of HK1231518A1 publication Critical patent/HK1231518A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6846—Common amplification features
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2545/00—Reactions characterised by their quantitative nature
    • C12Q2545/10—Reactions characterised by their quantitative nature the purpose being quantitative analysis
    • C12Q2545/113—Reactions characterised by their quantitative nature the purpose being quantitative analysis with an external standard/control, i.e. control reaction is separated from the test/target reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK17105265.8A 2014-07-09 2017-05-24 用於定量 轉錄物變體的方法和產物 HK1231518A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14176417 2014-07-09
PCT/EP2015/065756 WO2016005524A1 (en) 2014-07-09 2015-07-09 Methods and products for quantifying rna transcript variants

Publications (1)

Publication Number Publication Date
HK1231518A1 true HK1231518A1 (zh) 2017-12-22

Family

ID=51224706

Family Applications (1)

Application Number Title Priority Date Filing Date
HK17105265.8A HK1231518A1 (zh) 2014-07-09 2017-05-24 用於定量 轉錄物變體的方法和產物

Country Status (11)

Country Link
US (1) US10513726B2 (zh)
EP (1) EP3167076B1 (zh)
JP (3) JP6930910B2 (zh)
KR (1) KR102555447B1 (zh)
CN (1) CN106471134B (zh)
AU (1) AU2015286672B2 (zh)
CA (1) CA2954495C (zh)
DK (1) DK3167076T3 (zh)
HK (1) HK1231518A1 (zh)
LT (1) LT3167076T (zh)
WO (1) WO2016005524A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2848240C (en) 2011-09-16 2020-09-29 Lexogen Gmbh Nucleic acid transcription method
US10513726B2 (en) 2014-07-09 2019-12-24 Lexogen Gmbh Methods for controlled identification and/or quantification of transcript variants in one or more samples
CN106771194B (zh) * 2017-01-18 2018-07-20 青岛大学 一种检测病原微生物的方法
US10828330B2 (en) * 2017-02-22 2020-11-10 IO Bioscience, Inc. Nucleic acid constructs comprising gene editing multi-sites and uses thereof
SE541799C2 (en) * 2018-04-11 2019-12-17 David Yudovich Determination of frequency distribution of nucleotide sequence variants
CN116287306A (zh) * 2018-05-02 2023-06-23 北京康普森生物技术有限公司 一种基于基因分型鉴定滩羊的方法
EP3666904A1 (en) 2018-12-14 2020-06-17 Lexogen GmbH Nucleic acid amplification and identification method
EP3901284A1 (en) * 2020-04-20 2021-10-27 BMBK Invest BV Construct, kit and method for sample tracking
WO2021261966A1 (ko) 2020-06-26 2021-12-30 숙명여자대학교 산학협력단 사이클로덱스트린을 이용한 경구투여용 복합 조성물 및 이의 제조방법
KR102690574B1 (ko) 2020-06-26 2024-07-31 숙명여자대학교산학협력단 비타민 b1의 보호 및 전달을 위한 장용성 조성물
WO2023086441A1 (en) * 2021-11-12 2023-05-19 Regents Of The University Of Minnesota Compositions and methods for transcriptional activation
WO2023220742A2 (en) * 2022-05-13 2023-11-16 Ascidian Therapeutics, Inc. Abca4 trans-splicing molecules

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2593343B1 (fr) 1986-01-20 1988-03-25 Thomson Csf Matrice d'elements photosensibles et son procede de fabrication, procede de lecture associe, et application de cette matrice a la prise de vue d'images
WO2002072889A2 (en) * 2001-01-12 2002-09-19 Applera Corporation Methods and compositions for microarray control
JP2004532034A (ja) * 2001-05-07 2004-10-21 アマシャム・バイオサイエンス・コーポレイション 遺伝子発現分析システムでコントロールとして使用するための人工遺伝子のデザイン
US20040009512A1 (en) * 2002-05-02 2004-01-15 Manuel Ares Arrays for detection of products of mRNA splicing
WO2005086938A2 (en) * 2004-03-11 2005-09-22 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Artificial mutation controls for diagnostic testing
EP2333104A1 (en) * 2009-12-11 2011-06-15 Lexogen GmbH RNA analytics method
US10513726B2 (en) 2014-07-09 2019-12-24 Lexogen Gmbh Methods for controlled identification and/or quantification of transcript variants in one or more samples

Also Published As

Publication number Publication date
JP2017525341A (ja) 2017-09-07
CN106471134A (zh) 2017-03-01
CN106471134B (zh) 2021-11-12
LT3167076T (lt) 2022-02-10
JP6930910B2 (ja) 2021-09-01
US20170321248A1 (en) 2017-11-09
JP2020014478A (ja) 2020-01-30
WO2016005524A1 (en) 2016-01-14
CA2954495C (en) 2024-03-05
CA2954495A1 (en) 2016-01-14
KR20170028383A (ko) 2017-03-13
KR102555447B1 (ko) 2023-07-13
AU2015286672B2 (en) 2021-12-02
AU2015286672A1 (en) 2016-12-15
JP2021153588A (ja) 2021-10-07
US10513726B2 (en) 2019-12-24
DK3167076T3 (da) 2022-02-21
EP3167076A1 (en) 2017-05-17
EP3167076B1 (en) 2021-11-17

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