CN106456751B - 治疗指甲和头皮银屑病的方法 - Google Patents
治疗指甲和头皮银屑病的方法 Download PDFInfo
- Publication number
- CN106456751B CN106456751B CN201580017495.1A CN201580017495A CN106456751B CN 106456751 B CN106456751 B CN 106456751B CN 201580017495 A CN201580017495 A CN 201580017495A CN 106456751 B CN106456751 B CN 106456751B
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- antibody
- psoriasis
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Microbiology (AREA)
- Mycology (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461972638P | 2014-03-31 | 2014-03-31 | |
| US61/972,638 | 2014-03-31 | ||
| US201462031850P | 2014-07-31 | 2014-07-31 | |
| US62/031,850 | 2014-07-31 | ||
| US201462041879P | 2014-08-26 | 2014-08-26 | |
| US62/041,879 | 2014-08-26 | ||
| PCT/US2015/021613 WO2015153144A1 (en) | 2014-03-31 | 2015-03-19 | Methods of treating nail and scalp psoriasis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106456751A CN106456751A (zh) | 2017-02-22 |
| CN106456751B true CN106456751B (zh) | 2021-02-02 |
Family
ID=52808190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580017495.1A Active CN106456751B (zh) | 2014-03-31 | 2015-03-19 | 治疗指甲和头皮银屑病的方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20170174772A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3126392B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6596014B2 (cg-RX-API-DMAC7.html) |
| KR (2) | KR102530900B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN106456751B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015241373B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2944605C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2760002T3 (cg-RX-API-DMAC7.html) |
| MY (1) | MY184189A (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201607881SA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015153144A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7767206B2 (en) | 2006-10-02 | 2010-08-03 | Amgen Inc. | Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto |
| PT3295957T (pt) | 2010-01-15 | 2019-11-12 | Kirin Amgen Inc | Formulação de anticorpo anti il-17ra e regimes terapêuticos para o tratamento de psoríase |
| CN105534996B (zh) * | 2016-02-24 | 2018-05-01 | 长沙佰顺生物科技有限公司 | 一种治疗银屑病的药物组合物 |
| GB201612043D0 (en) * | 2016-07-11 | 2016-08-24 | Crescendo Biologics Ltd | Composition for treatment of disorders |
| JP7033774B2 (ja) * | 2017-08-25 | 2022-03-11 | 国立大学法人 東京大学 | 抗サイトカイン抗体療法 |
| CN111670036B (zh) * | 2018-01-31 | 2024-08-09 | 安成生物科技股份有限公司 | 包含托法替尼的局部调配物 |
| US12161748B2 (en) | 2018-01-31 | 2024-12-10 | Twi Biotechnology, Inc. | Topical formulations comprising tofacitinib |
| CA3091598A1 (en) | 2018-02-22 | 2019-08-29 | Tokai University Educational System | Il-17a activity inhibitor and use thereof |
| JOP20210229A1 (ar) | 2019-02-18 | 2023-01-30 | Lilly Co Eli | صيغة جسم مضاد علاجي |
| JP2022547678A (ja) * | 2019-09-11 | 2022-11-15 | ボシュ ヘルス アイルランド リミテッド | Il-17ra抗体を用いた非アルコール性脂肪性肝疾患(nafld)の治療方法 |
| CN114423455A (zh) * | 2019-09-25 | 2022-04-29 | 国立大学法人东京大学 | 用于治疗系统性硬化症的药物组合物 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101541833A (zh) * | 2006-10-02 | 2009-09-23 | 安姆根有限公司 | Il-17受体a抗原结合蛋白质 |
| CN102821787A (zh) * | 2010-01-15 | 2012-12-12 | 麒麟-安姆根有限公司 | 抗体制剂和治疗方案 |
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| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| IL98078A0 (en) | 1991-05-07 | 1992-06-21 | Yeda Res & Dev | Pharmaceutical compositions comprising an anticytokyne |
| IL83878A (en) | 1987-09-13 | 1995-07-31 | Yeda Res & Dev | Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it |
| US5204244A (en) | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
| GB8807803D0 (en) | 1988-03-31 | 1988-05-05 | Glaxo Group Ltd | Biochemical product |
| AU631545B2 (en) | 1988-04-15 | 1992-12-03 | Protein Design Labs, Inc. | Il-2 receptor-specific chimeric antibodies |
| IL94039A (en) | 1989-08-06 | 2006-09-05 | Yeda Res & Dev | Antibodies to tbp - 1 and their use |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| DE59010941D1 (de) | 1989-04-21 | 2005-03-24 | Amgen Inc | TNF-Rezeptor, TNF bindende Proteine und dafür kodierende DNAs |
| DE3922089A1 (de) | 1989-05-09 | 1990-12-13 | Basf Ag | Neue proteine und ihre herstellung |
| EP0398327B2 (en) | 1989-05-18 | 2013-02-20 | Yeda Research And Development Co., Ltd. | Tumor necrosis factor binding protein II, its purification and antibodies thereto |
| IL95031A (en) | 1989-07-18 | 2007-03-08 | Amgen Inc | Method for the production of a human recombinant tumor necrosis factor inhibitor |
| US5395760A (en) | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| CA2065346C (en) | 1989-09-05 | 2005-03-29 | Craig A. Smith | Tumor necrosis factor-.alpha. and-.beta. receptors |
| DE10399023I2 (de) | 1989-09-12 | 2006-11-23 | Ahp Mfg B V | TFN-bindende Proteine |
| JPH03127800A (ja) | 1989-10-13 | 1991-05-30 | Teijin Ltd | 腫瘍壊死因子活性抑制物質 |
| JPH0578396A (ja) | 1989-12-13 | 1993-03-30 | Yeda Res & Dev Co Ltd | ヒト腫瘍壊死因子結合蛋白 |
| US5136021A (en) | 1990-02-27 | 1992-08-04 | Health Research, Inc. | TNF-inhibitory protein and a method of production |
| US6552170B1 (en) | 1990-04-06 | 2003-04-22 | Amgen Inc. | PEGylation reagents and compounds formed therewith |
| US6458360B1 (en) | 1990-04-25 | 2002-10-01 | The Johns Hopkins University | Soluble complement regulatory molecules |
| GB2246569A (en) | 1990-06-15 | 1992-02-05 | Charing Cross Sunley Research | Tumour necrosis factor - alpha binding protein |
| ATE169030T1 (de) | 1990-06-28 | 1998-08-15 | Hoechst Ag | Fusionsproteine mit immunglobulinanteilen, ihre herstellung und verwendung |
| WO1992001002A1 (en) | 1990-07-11 | 1992-01-23 | Teijin Limited | Tumor necrosis factor activity inhibitor and production thereof |
| WO1992013095A1 (en) | 1991-01-18 | 1992-08-06 | Synergen, Inc. | Methods for treating tumor necrosis factor mediated diseases |
| SG89295A1 (en) | 1991-03-15 | 2002-06-18 | Amgen Inc | Pegylation of polypeptides |
| IL99120A0 (en) | 1991-08-07 | 1992-07-15 | Yeda Res & Dev | Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them |
| WO1993007863A1 (en) | 1991-10-15 | 1993-04-29 | Mullarkey Michael F | Methods and compositions for treating allergic reactions |
| EP1239043A3 (en) | 1992-03-30 | 2003-01-02 | Immunex Corporation | Fusion proteins comprising tumour necrosis factor receptor |
| JPH07509223A (ja) | 1992-04-30 | 1995-10-12 | アムジェン インコーポレイテッド | インターロイキン−1媒介疾患および腫瘍壊死因子媒介疾患の治療方法 |
| JPH05312248A (ja) | 1992-05-08 | 1993-11-22 | Nissan Motor Co Ltd | シフトレバー装置 |
| NZ256293A (en) | 1992-09-15 | 1997-06-24 | Immunex Corp | Method of treating tumour necrosis factor - mediated inflammation by use of tnf antagonist |
| JP3720353B2 (ja) | 1992-12-04 | 2005-11-24 | メディカル リサーチ カウンシル | 多価および多重特異性の結合タンパク質、それらの製造および使用 |
| US5869286A (en) | 1995-03-23 | 1999-02-09 | Immunex Corporation | Receptor that binds IL-17 |
| US7030565B2 (en) | 2004-07-27 | 2006-04-18 | Jerrell Penn Hollaway | Lamp control circuit with selectable color signals |
| MX2007015476A (es) | 2005-06-14 | 2008-02-25 | Amgen Inc | Formulaciones de proteina autoamortiguadoras. |
| US7767206B2 (en) | 2006-10-02 | 2010-08-03 | Amgen Inc. | Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto |
| JP5537740B2 (ja) * | 2010-10-08 | 2014-07-02 | ノバルティス アーゲー | Il−17アンタゴニストを用いて乾癬を治療する方法 |
| US9413463B2 (en) | 2013-08-30 | 2016-08-09 | Google Inc. | Apparatus and method for efficient two-way optical communication where transmitter may interfere with receiver |
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-
2015
- 2015-03-19 KR KR1020227021274A patent/KR102530900B1/ko active Active
- 2015-03-19 CA CA2944605A patent/CA2944605C/en active Active
- 2015-03-19 EP EP15714136.7A patent/EP3126392B1/en active Active
- 2015-03-19 CN CN201580017495.1A patent/CN106456751B/zh active Active
- 2015-03-19 AU AU2015241373A patent/AU2015241373B2/en active Active
- 2015-03-19 KR KR1020167026333A patent/KR20160130248A/ko not_active Ceased
- 2015-03-19 US US15/129,811 patent/US20170174772A1/en not_active Abandoned
- 2015-03-19 SG SG11201607881SA patent/SG11201607881SA/en unknown
- 2015-03-19 WO PCT/US2015/021613 patent/WO2015153144A1/en not_active Ceased
- 2015-03-19 MY MYPI2016001729A patent/MY184189A/en unknown
- 2015-03-19 JP JP2016559626A patent/JP6596014B2/ja active Active
- 2015-03-19 ES ES15714136T patent/ES2760002T3/es active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101541833A (zh) * | 2006-10-02 | 2009-09-23 | 安姆根有限公司 | Il-17受体a抗原结合蛋白质 |
| CN102821787A (zh) * | 2010-01-15 | 2012-12-12 | 麒麟-安姆根有限公司 | 抗体制剂和治疗方案 |
Non-Patent Citations (4)
| Title |
|---|
| Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Psoriasis;Jashin J. Wu, M.D.等;《T h e new engl and journa l o f medicine》;20120329;第366卷(第13期);274-275 * |
| Brodalumab, an Anti–Interleukin-17–Receptor Antibodyfor Psoriasis;Kim A. Papp, M.D.,等;《T h e new engl and journa l o f medicine》;20120329;第366卷(第13期);1181-1189 * |
| Treatment of severe scalp psoriasis: From the Medical Board of the National Psoriasis Foundation;C. Stanley Chan等;《J AM ACAD DERMATOL》;20090420;第60卷(第6期);962-971 * |
| 英夫利昔单抗诱导和维持治疗中重度银屑病的三期临床多中心双盲对照试验;reich k等;《世界核心医学期刊文摘 皮肤病学》;20060131;第2卷(第1期);1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106456751A (zh) | 2017-02-22 |
| US20170174772A1 (en) | 2017-06-22 |
| EP3126392B1 (en) | 2019-09-11 |
| WO2015153144A1 (en) | 2015-10-08 |
| KR102530900B1 (ko) | 2023-05-12 |
| EP3126392A1 (en) | 2017-02-08 |
| JP6596014B2 (ja) | 2019-10-23 |
| ES2760002T3 (es) | 2020-05-12 |
| CA2944605A1 (en) | 2015-10-08 |
| AU2015241373B2 (en) | 2020-11-05 |
| JP2017511316A (ja) | 2017-04-20 |
| MY184189A (en) | 2021-03-24 |
| KR20220093008A (ko) | 2022-07-04 |
| SG11201607881SA (en) | 2016-10-28 |
| AU2015241373A1 (en) | 2016-10-06 |
| CA2944605C (en) | 2023-10-17 |
| KR20160130248A (ko) | 2016-11-10 |
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| CB02 | Change of applicant information | ||
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Address after: American California Applicant after: Amgen K-A Co., Ltd. Address before: American California Applicant before: Kirin Amgen Inc |
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Address after: California, USA Patentee after: Amgen K-a Co. Address before: California, USA Patentee before: Amgen K-A Co.,Ltd. |