CN106456554B - 修饰释放的包衣胶囊 - Google Patents

修饰释放的包衣胶囊 Download PDF

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Publication number
CN106456554B
CN106456554B CN201580025649.1A CN201580025649A CN106456554B CN 106456554 B CN106456554 B CN 106456554B CN 201580025649 A CN201580025649 A CN 201580025649A CN 106456554 B CN106456554 B CN 106456554B
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China
Prior art keywords
capsule
coating
modified release
capsules
film
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CN201580025649.1A
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English (en)
Chinese (zh)
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CN106456554A (zh
Inventor
R.C.布拉沃冈萨雷斯
F.J.奥利维拉瓦鲁姆
T.布塞尔
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Tillotts Pharma AG
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Tillotts Pharma AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules

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  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201580025649.1A 2014-05-19 2015-05-13 修饰释放的包衣胶囊 Active CN106456554B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14168871.3A EP2946773A1 (en) 2014-05-19 2014-05-19 Modified release coated capsules
EP14168871.3 2014-05-19
PCT/EP2015/060638 WO2015177028A1 (en) 2014-05-19 2015-05-13 Modified release coated capsules

Publications (2)

Publication Number Publication Date
CN106456554A CN106456554A (zh) 2017-02-22
CN106456554B true CN106456554B (zh) 2021-03-09

Family

ID=50732832

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580025649.1A Active CN106456554B (zh) 2014-05-19 2015-05-13 修饰释放的包衣胶囊

Country Status (12)

Country Link
US (1) US11160762B2 (enExample)
EP (2) EP2946773A1 (enExample)
JP (2) JP2017515879A (enExample)
CN (1) CN106456554B (enExample)
AU (1) AU2015263311B2 (enExample)
CA (1) CA2946938C (enExample)
DK (1) DK3145497T3 (enExample)
ES (1) ES2832699T3 (enExample)
HK (1) HK1215385A1 (enExample)
NZ (1) NZ725577A (enExample)
SI (1) SI3145497T1 (enExample)
WO (1) WO2015177028A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7650660B2 (ja) 2017-11-17 2025-03-25 エボニック オペレーションズ ゲーエムベーハー コーティングされた硬カプセルを製造する方法
CN109330988A (zh) * 2018-11-14 2019-02-15 广西达庆生物科技有限公司 一种含有抗菌药物的药敏胶囊及其制备方法
CA3137514A1 (en) 2019-05-15 2020-11-19 Vinay JAIN Process for preparing filled hard-shell capsules with (meth)acrylate copolymer based coatings with a capsule-filling machine
EP3968967B1 (en) 2019-05-15 2025-11-26 Evonik Operations GmbH Process for preparing filled hard-shell capsules with cellulose or starch-based coatings with a capsule-filling machine
CN111388454A (zh) * 2020-04-05 2020-07-10 刘立新 一种消化道定时崩解胶囊及其生产工艺
GB202006074D0 (en) * 2020-04-24 2020-06-10 Vicore Pharma Ab New composition
CN112472715B (zh) * 2020-12-18 2023-06-23 华熙生物科技股份有限公司 一种碳酸氢钠肠溶胶囊及其制备方法
CN117241788A (zh) 2021-04-20 2023-12-15 江苏恒瑞医药股份有限公司 用于药物特定递送的胶囊及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6229515A (ja) 1985-07-30 1987-02-07 Shinjiro Tsuji 硬カプセル剤のフイルムコ−テイング方法
WO2003013480A1 (en) * 2001-08-06 2003-02-20 Dr. Reddy's Laboratories Ltd. Improved enteric formulation of fluoxetin
US20030124196A1 (en) * 2001-08-22 2003-07-03 Susan Weinbach Pulsatile release compositions and methods for enhanced intestinal drug absorption
US8168170B2 (en) * 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
EP2243487A1 (en) 2009-04-23 2010-10-27 Actogenix N.V. Enteric coated formulation
AU2012322323B2 (en) * 2011-10-11 2016-04-21 Sun Pharmaceutical Industries Limited A gastroretentive dosage system and process of preparation thereof
JP6062802B2 (ja) 2012-08-23 2017-01-18 日清ファルマ株式会社 キトサン含有組成物及びキトサンコーティング組成物
EP2968187A4 (en) 2013-03-14 2016-08-17 Therabiome Llc TARGETED GASTROINTESTINAL RELEASE OF PROBIOTIC ORGANISMS AND / OR THERAPEUTICS

Also Published As

Publication number Publication date
HK1215385A1 (en) 2016-08-26
CN106456554A (zh) 2017-02-22
AU2015263311B2 (en) 2020-01-16
CA2946938A1 (en) 2015-11-26
AU2015263311A1 (en) 2016-11-10
JP2017515879A (ja) 2017-06-15
CA2946938C (en) 2022-07-12
EP3145497B1 (en) 2020-10-28
NZ725577A (en) 2023-06-30
EP3145497A1 (en) 2017-03-29
US11160762B2 (en) 2021-11-02
JP7041333B2 (ja) 2022-03-24
DK3145497T3 (da) 2020-11-09
WO2015177028A1 (en) 2015-11-26
JP2020063290A (ja) 2020-04-23
ES2832699T3 (es) 2021-06-11
SI3145497T1 (sl) 2021-01-29
US20170079927A1 (en) 2017-03-23
EP2946773A1 (en) 2015-11-25

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