CN106421319B - A kind of aquatic products Chinese herbal medicine for the treatment of fungal disease and preparation method thereof - Google Patents

A kind of aquatic products Chinese herbal medicine for the treatment of fungal disease and preparation method thereof Download PDF

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CN106421319B
CN106421319B CN201610945488.4A CN201610945488A CN106421319B CN 106421319 B CN106421319 B CN 106421319B CN 201610945488 A CN201610945488 A CN 201610945488A CN 106421319 B CN106421319 B CN 106421319B
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李官昊
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LINXIANG DONGSHENG BIOTECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/44Elemental carbon, e.g. charcoal, carbon black
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells

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Abstract

A kind of Chinese herbal medicine the invention discloses aquatic products with treatment fungal disease, it is made up of the raw material matched by following mass fraction:60 120 parts of Radix Isatidis, 40 80 parts of honeysuckle, 30 70 parts of fritillaria thunbergii, 10 20 parts of Chinese gall, 15 25 parts of cordate houttuynia, 4 12 parts of wormwood, 5 15 parts of lotus leaf, 39 parts of cicada slough, 15 parts of snake gall, 15 parts of charcoal.The preparation method is produced including main ingredient, auxiliary is produced, adjuvant is produced, soft material is produced, is granulated and drying and other steps, it has extraordinary curative effect to the fungal disease as caused by water mold, the gill are mould etc. such as fish shrimp crab soft-shelled turtle frog, immunity of the aquatic livestock to the disease can be improved, promotes the healthy growth of fish.

Description

A kind of aquatic products Chinese herbal medicine for the treatment of fungal disease and preparation method thereof
Technical field
The present invention relates to fishes and shrimps disease therapeuticing medicine field, more particularly to a kind of aquatic products is with treatment fungal disease Herbal medicine and preparation method thereof method.
Background technology
In recent years, as the continuous improvement of aquaculture intensive degree, cultivation density increasingly increase, the disease of fish shrimp crab class Also getting worse occurs for disease, and the wherein fungal disease such as the saprolegniasis of the aquatic livestock such as fish shrimp crab class, branchiomycosis turns into more normal The disease of hair, once these diseases occur, i.e., heavy losses can be brought to raiser, therefore research and develop one kind to prevent and treat such disease Chinese medicine preparation there is stock index, in addition with the food-safe attention of society, meet the pure of pollution-free food trend Chinese medicine aquatic medicine is the direction of aquaculture drug development.Traditional traditional Chinese powder medicine is only made by being mixed after common crushing It is standby so that the drug effect of Chinese medicine can not be completely absorbed, so as to reduce the therapeutic effect of medicine.
The content of the invention
First purpose of the present invention is to be directed to problem above, there is provided a kind of aquatic products uses the medium-height grass for the treatment of fungal disease Medicine, it has extraordinary curative effect to the fungal disease as caused by water mold, the gill are mould etc. such as fish shrimp crab soft-shelled turtle frog, can improve aquatic products and move Thing promotes the healthy growth of fish to the immunity of the disease.
To realize the purpose, the technical solution adopted by the present invention is:A kind of Chinese herbal medicine of aquatic products treatment fungal disease, It is made up of the raw material matched by following mass fraction:Radix Isatidis 60-120 parts, honeysuckle 40-80 parts, fritillaria thunbergii 30-70 parts, Chinese gall 10-20 parts, cordate houttuynia 15-25 parts, wormwood 4-12 parts, lotus leaf 5-15 parts, cicada slough 3-9 parts, snake gall 1-5 parts, charcoal 1-5 Part.
Preferably, it is made up of the raw material matched by following mass fraction:80 parts of Radix Isatidis, 60 parts of honeysuckle, fritillaria thunbergii 50 parts, 15 parts of Chinese gall, 20 parts of cordate houttuynia, 8 parts of wormwood, 10 parts of lotus leaf, 6 parts of cicada slough, 3 parts of snake gall, 3 parts of charcoal.
A kind of preparation method it is a further object to provide aquatic products with the Chinese herbal medicine for the treatment of fungal disease, should Method can make it that the drug effect of the Chinese herbal medicine prepared is higher, promote the absorption of drug effect, while can effectively remove in Chinese herbal medicine and have The side effect of poison, further improves the medicine drug effect.
To realize the purpose, a kind of aquatic products preparation method of the Chinese herbal medicine for the treatment of fungal disease includes following prepare and walked Suddenly:
(1)Main ingredient is produced:By the Radix Isatidis of proportioning selection fresh dried, honeysuckle, fritillaria thunbergii, Chinese gall, cicada slough, lotus Leaf, it is put into after being crushed in pulverizer and main ingredient powder is made;
(2)Auxiliary is produced:It is put into scald in 90-100 DEG C of water by cordate houttuynia, the wormwood of proportioning selection fresh dried and boils 2-5 points Taken out after clock, be put into pallet and spread out, be placed under illumination firing equipment and heat, and transparent membrane is coverd with tray upper surface, tieed up Illumination temperature is held as 40-45 DEG C, after continuing 1-2 as a child, removes transparent membrane, after then being crushed by pulverizer, pair is made Medicinal powder end;
(3)Adjuvant is produced:Fresh snake bile is put into vacuum desiccator by proportioning and is dried, obtains green-yellow Crystalline powder, powder is put into pallet and spread out, be placed under ultraviolet germicidal lamp after irradiating 30-60 minutes, form adjuvant powder;
(4)Soft material is produced:Main ingredient powder, auxiliary powder, adjuvant powder, charcoal are put into container by proportioning and are well mixed And the alcohol that concentration is 8-10% is added, adjustment humidity of materials is 20-30%, forms soft material;
(5)It is granulated and dries:Soft material is put into comminutor and is granulated, forms wet grain;The wet grain is placed in 50-60 Dried in DEG C illumination drying box, form dry particle.
Further, the step(1)During main ingredient is produced, the main ingredient powder diameter is 40-50 μm.
Further, the step(2)During auxiliary is produced, cordate houttuynia, wormwood that fresh dried is chosen by proportioning are put into 90- Scald in 100 DEG C of water and taken out after boiling 2-5 minutes, be put into pallet and spread out, be placed under illumination firing equipment and heat, and in pallet upper table Transparent membrane is coverd with face, and it is 40-45 DEG C to maintain illumination temperature, after continuing 1-2 as a child, is removed transparent membrane, is continued illumination 20- After 30 minutes, after then being crushed by pulverizer, auxiliary powder is made.
Further, the step(3)During adjuvant is produced, it is 50-60%'s that fresh snake bile is put into concentration by proportioning After soaking 24-48 hours in alcohol, place into vacuum desiccator and be dried, obtain the crystalline powder of green-yellow, by powder It is put into pallet and spreads out, be placed under ultraviolet germicidal lamp after irradiating 30-60 minutes, forms adjuvant powder.
Further, the step(4)During soft material is produced, by proportioning by main ingredient powder, auxiliary powder, adjuvant powder, wood Charcoal is put into the alcohol for being well mixed and adding that concentration is 8-10% in container, and adjustment humidity of materials is 20-30%, maintains storage temperature For 25-30 DEG C, sealed storage forms soft material after 24-48 hours.
Further, the step(5)In being granulated and drying, moisture is reduced to 3% ~ 5% in the dry particle.
Beneficial effects of the present invention:
Radix Isatidis has heat-clearing, removing toxic substances, cool blood, the effect of relieving sore-throat, Return liver, stomach;Honeysuckle is cold in nature sweet, has heat-clearing Removing toxic substances, cool bloodization become silted up the effect of, cure mainly affection of exogenous wind-heat, seasonal febrile diseases from the beginning of.
Fritillaria thunbergii, the big hardship of taste is cold in nature, has clearing heat and eliminating phlegm, powder detoxifcation.Control cough due to wind-heat evil, lung carbuncle larynx numbness, scrofula, sore Ulcer pyogenic infections.
Chinese gall:It is sour, it is puckery, it is cold in nature.Return lung, large intestine, kidney channel, astringe the lung;Hidroschesis;Puckery intestines;Controlling nocturnal emission with astringent drugs;Hemostasis;Removing toxic substances.
Cordate houttuynia:Cold nature, bitter, weak poison, there is anti-bacteria and anti-virus, improve the drug effect such as immunity of organisms, anti-inflammatory.
Wormwood:It is bitter in taste, pungent, warm, it is poisonous, enter spleen, liver, kidney, there is the drug effects such as antibacterial, antimycotic, cholagogic, hemostasis.
Lotus leaf:Nature and flavor are bitter, put down, Return liver, spleen, stomach, the heart channel of Hang-Shaoyin, have the work(such as clearing summer-heat and damp, sending up the lucid yang, cooling blood and hemostasis Effect.But also there is antimitotic effect, there is stronger fungistatic effect, there is the drug effects such as dredging, toxin expelling, fall fire, detumescence.
Cicada slough:It is sweet, tremble with fear.Return lung, Liver Channel, have and dissipate wind except heat, relieving sore-throat, promoting eruption, move back screen, spasmolysis.For anemopyretic cold, Pharyngalgia, sound is mute, measles without adequate eruption, rubella itch, the drug effect such as cataract.
Snake gall:It is cool in nature, bitter but slightly sweet taste;The effect of miliaria being removed with dispelling wind and eliminating dampness, refrigerant improving eyesight, removing toxic substances;Adjustable benefit nerveous system System, internal system and immune system.
Charcoal, there are gut purge stomach, detoxify, except sore acts on.
Radix Isatidis, honeysuckle, fritillaria thunbergii, Chinese gall, cordate houttuynia, wormwood, lotus leaf, cicada slough, snake gall, charcoal are reasonably mixed After being combined, the preparation method by the present invention is produced can be so that the toxicity in wormwood, snake gall, cordate houttuynia be removed, together When promote Chinese herbal medicine drug effect, have preferable astringing to arrest bleeding, hygroscopic sore, it is antimycotic, improve immunity the effect of, can treat Include the fungal disease of a variety of aquatic product animals of water mold, the gill including mould etc..
Embodiment
In order to facilitate the understanding of the purposes, features and advantages of the present invention, below to the specific reality of the present invention The mode of applying elaborates.Many details are elaborated in the following description in order to fully understand the present invention.But this Invention can be implemented with being much different from other modes described here, and those skilled in the art can be without prejudice to the present invention Similar improvement is done in the case of intension, therefore the present invention is not limited to the specific embodiments disclosed below.
Embodiment one:
A kind of aquatic products Chinese herbal medicine for the treatment of fungal disease, it is made up of the raw material matched by following mass fraction:Plate Blue 60 parts of root, 40 parts of honeysuckle, 30 parts of fritillaria thunbergii, 10 parts of Chinese gall, 15 parts of cordate houttuynia, 4 parts of wormwood, 5 parts of lotus leaf, 3 parts of cicada slough, 1 part of snake gall, 1 part of charcoal.
Embodiment two:
A kind of aquatic products Chinese herbal medicine for the treatment of fungal disease, it is made up of the raw material matched by following mass fraction:Plate Blue 120 parts of root, 80 parts of honeysuckle, 70 parts of fritillaria thunbergii, 20 parts of Chinese gall, 25 parts of cordate houttuynia, 12 parts of wormwood, 15 parts of lotus leaf, cicada slough 9 Part, 5 parts of snake gall, 5 parts of charcoal.
Embodiment three:
A kind of aquatic products Chinese herbal medicine for the treatment of fungal disease, it is made up of the raw material matched by following mass fraction:Plate Blue 80 parts of root, 60 parts of honeysuckle, 50 parts of fritillaria thunbergii, 15 parts of Chinese gall, 20 parts of cordate houttuynia, 8 parts of wormwood, 10 parts of lotus leaf, cicada slough 6 Part, 3 parts of snake gall, 3 parts of charcoal.
A kind of aquatic products includes following preparation process with the preparation method of the Chinese herbal medicine for the treatment of fungal disease:
(1)Main ingredient is produced:By the Radix Isatidis of proportioning selection fresh dried, honeysuckle, fritillaria thunbergii, Chinese gall, cicada slough, lotus Leaf, it is put into after being crushed in pulverizer and main ingredient powder is made;
(2)Auxiliary is produced:It is put into scald in 90-100 DEG C of water by cordate houttuynia, the wormwood of proportioning selection fresh dried and boils 2-5 points Taken out after clock, be put into pallet and spread out, be placed under illumination firing equipment and heat, and transparent membrane is coverd with tray upper surface, tieed up Illumination temperature is held as 40-45 DEG C, after continuing 1-2 as a child, removes transparent membrane, after then being crushed by pulverizer, pair is made Medicinal powder end;
(3)Adjuvant is produced:Fresh snake bile is put into vacuum desiccator by proportioning and is dried, obtains green-yellow Crystalline powder, powder is put into pallet and spread out, be placed under ultraviolet germicidal lamp after irradiating 30-60 minutes, form adjuvant powder;
(4)Soft material is produced:Main ingredient powder, auxiliary powder, adjuvant powder, charcoal are put into container by proportioning and are well mixed And the alcohol that concentration is 8-10% is added, adjustment humidity of materials is 20-30%, forms soft material;
(5)It is granulated and dries:Soft material is put into comminutor and is granulated, forms wet grain;The wet grain is placed in 50-60 Dried in DEG C illumination drying box, form dry particle.
Preferably, the step(1)During main ingredient is produced, the main ingredient powder diameter is 40-50 μm.
Preferably, the step(2)During auxiliary is produced, cordate houttuynia, wormwood that fresh dried is chosen by proportioning are put into 90- Scald in 100 DEG C of water and taken out after boiling 2-5 minutes, be put into pallet and spread out, be placed under illumination firing equipment and heat, and in pallet upper table Transparent membrane is coverd with face, and it is 40-45 DEG C to maintain illumination temperature, after continuing 1-2 as a child, is removed transparent membrane, is continued illumination 20- After 30 minutes, after then being crushed by pulverizer, auxiliary powder is made.
Preferably, the step(3)During adjuvant is produced, fresh snake bile is put into the wine that concentration is 50-60% by proportioning After soaking 24-48 hours in essence, place into vacuum desiccator and be dried, obtain the crystalline powder of green-yellow, powder is put Enter in pallet and spread out, be placed under ultraviolet germicidal lamp after irradiating 30-60 minutes, form adjuvant powder.
Preferably, the step(4)During soft material is produced, by proportioning by main ingredient powder, auxiliary powder, adjuvant powder, charcoal The alcohol for being well mixed and adding that concentration is 8-10% in container is put into, adjustment humidity of materials is 20-30%, and maintenance storage temperature is 25-30 DEG C, sealed storage forms soft material after 24-48 hours.
Preferably, the step(5)In being granulated and drying, moisture is reduced to 3% ~ 5% in the dry particle.
In preparation method, step(2)In, cordate houttuynia, wormwood be put into 90-100 DEG C of water scald boil 2-5 minutes after take out, put Enter in pallet and spread out, be placed under illumination firing equipment and heat, and transparent membrane is coverd with tray upper surface, maintenance illumination temperature is 40-45 DEG C, after continuing 1-2 as a child, remove transparent membrane, after continuing illumination 20-30 minutes, can effectively get rid of fish raw meat Toxicity in grass, wormwood, then again by can further get rid of toxicity therein after the mediation of charcoal and alcohol.
Step(3)During adjuvant is produced, fresh snake bile is put into the alcohol that concentration is 50-60% by proportioning and soaks 24- After 48 hours, place into vacuum desiccator and be dried, obtain the crystalline powder of green-yellow, powder is put into pallet and spread out Open, be placed under ultraviolet germicidal lamp after irradiating 30-60 minutes, form adjuvant powder, can effectively get rid of the poison in snake gall Property and parasite, by toxicity be converted to protein can improve drug effect and can promote aquatic biological growth.
This product is specifically used:Mix bait to feed, per 1kg body weight 0.1-02g 3 times a day, 5-7 days are used in conjunction in aquatic livestock.Sprinkle Spill, every 1 cubic metre of water body, aquatic livestock 0.3g, be used in conjunction 2.
Points for attention:1st, flowing water, cage culture etc. please take the circumstances into consideration dosage because of water body flow;When the 2nd, preventing saprolegniasis, branchiomycosis If being in a bad way, dosage can be taken the circumstances into consideration.
Storage:It is closed, moistureproof, high temperature-proof.
Using this product in static waters to aquatic product treatment of animals Experimental comparison's data with fungal disease:
By finding the true of a variety of aquatic product animals of this product including mould etc. for water mold, the gill after many experiments use Bacterium property disease has the effect of preferable really.
It should be noted that herein, term " comprising ", "comprising" or its any other variant are intended to non-row His property includes, so that process, method, article or equipment including a series of elements not only include those key elements, and And also include the other element being not expressly set out, or also include for this process, method, article or equipment institute inherently Key element.
Specific case used herein is set forth to the principle and embodiment of the present invention, the explanation of above example It is only intended to help the method and its core concept for understanding the present invention.Described above is only the preferred embodiment of the present invention, should When pointing out due to the finiteness of literal expression, and unlimited concrete structure objectively be present, for the common skill of the art For art personnel, under the premise without departing from the principles of the invention, some improvement, retouching or change can also be made, can also incited somebody to action Above-mentioned technical characteristic is combined by rights;These improve retouching, change or combination, or the not improved structure by invention Think and technical scheme directly applies to other occasions, be regarded as protection scope of the present invention.

Claims (7)

1. a kind of aquatic products Chinese herbal medicine for the treatment of fungal disease, it is characterised in that it presses the raw material of following mass fraction proportioning It is made:Radix Isatidis 60-120 parts, honeysuckle 40-80 parts, fritillaria thunbergii 30-70 parts, Chinese gall 10-20 parts, cordate houttuynia 15-25 parts, Wormwood 4-12 parts, lotus leaf 5-15 parts, cicada slough 3-9 parts, snake gall 1-5 parts, charcoal 1-5 parts;
A kind of described aquatic products includes following preparation process with the preparation method of the Chinese herbal medicine for the treatment of fungal disease:
(1)Main ingredient is produced:Radix Isatidis, honeysuckle, fritillaria thunbergii, Chinese gall, cicada slough, the lotus leaf of fresh dried are chosen by proportioning, is put Enter and main ingredient powder is made after being crushed in pulverizer;
(2)Auxiliary is produced:By proportioning choose fresh dried cordate houttuynia, wormwood be put into 90-100 DEG C of water scald boil 2-5 minutes after Take out, be put into pallet and spread out, be placed under illumination firing equipment and heat, and transparent membrane is coverd with tray upper surface, maintain light It is 40-45 DEG C according to temperature, after continuing 1-2 hours, removes transparent membrane, after then being crushed by pulverizer, auxiliary powder is made;
(3)Adjuvant is produced:Fresh snake bile is put into vacuum desiccator by proportioning and is dried, obtains the crystallization of green-yellow Powder, powder is put into pallet and spread out, be placed under ultraviolet germicidal lamp after irradiating 30-60 minutes, form adjuvant powder;
(4)Soft material is produced:Main ingredient powder, auxiliary powder, adjuvant powder, charcoal are put into container by proportioning and is well mixed and adds Enter the alcohol that concentration is 8-10%, adjustment humidity of materials is 20-30%, forms soft material;
(5)It is granulated and dries:Soft material is put into comminutor and is granulated, forms wet grain;The wet grain is placed in 50-60 DEG C of light Dried according in drying box, form dry particle.
2. the Chinese herbal medicine of a kind of aquatic products treatment fungal disease according to claim 1, it is characterised in that it is by by such as The raw material of lower mass fraction proportioning is made:80 parts of Radix Isatidis, 60 parts of honeysuckle, 50 parts of fritillaria thunbergii, 15 parts of Chinese gall, cordate houttuynia 20 Part, 8 parts of wormwood, 10 parts of lotus leaf, 6 parts of cicada slough, 3 parts of snake gall, 3 parts of charcoal.
A kind of 3. Chinese herbal medicine of aquatic products treatment fungal disease according to claim 1, it is characterised in that the step (1)During main ingredient is produced, the main ingredient powder diameter is 40-50 μm.
A kind of 4. Chinese herbal medicine of aquatic products treatment fungal disease according to claim 1, it is characterised in that the step (2)During auxiliary is produced, by proportioning choose fresh dried cordate houttuynia, wormwood be put into 90-100 DEG C of water scald boil 2-5 minutes after take Go out, be put into pallet and spread out, be placed under illumination firing equipment and heat, and transparent membrane is coverd with tray upper surface, maintain illumination Temperature is 40-45 DEG C, after continuing 1-2 hours, removes transparent membrane, after continuing illumination 20-30 minutes, then passes through pulverizer powder After broken, auxiliary powder is made.
A kind of 5. Chinese herbal medicine of aquatic products treatment fungal disease according to claim 1, it is characterised in that the step (3)During adjuvant is produced, fresh snake bile is put into the alcohol that concentration is 50-60% after immersion 24-48 hours by proportioning, then It is put into vacuum desiccator and is dried, obtains the crystalline powder of green-yellow, powder is put into pallet and spread out, be placed in ultraviolet After irradiating 30-60 minutes under bactericidal lamp, adjuvant powder is formed.
A kind of 6. Chinese herbal medicine of aquatic products treatment fungal disease according to claim 1, it is characterised in that the step (4)During soft material is produced, main ingredient powder, auxiliary powder, adjuvant powder, charcoal are put into by proportioning and is well mixed and adds in container Concentration is 8-10% alcohol, and adjustment humidity of materials is 20-30%, and it is 25-30 DEG C to maintain storage temperature, and sealed storage 24-48 is small When after form soft material.
A kind of 7. Chinese herbal medicine of aquatic products treatment fungal disease according to claim 1, it is characterised in that the step (5)In being granulated and drying, moisture is reduced to 3% ~ 5% in the dry particle.
CN201610945488.4A 2016-10-26 2016-10-26 A kind of aquatic products Chinese herbal medicine for the treatment of fungal disease and preparation method thereof Active CN106421319B (en)

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