CN106389223A - Violate seaweed containing multi sugar combination and respective use thereof - Google Patents
Violate seaweed containing multi sugar combination and respective use thereof Download PDFInfo
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- CN106389223A CN106389223A CN201611013549.XA CN201611013549A CN106389223A CN 106389223 A CN106389223 A CN 106389223A CN 201611013549 A CN201611013549 A CN 201611013549A CN 106389223 A CN106389223 A CN 106389223A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention discloses violate seaweed containing multi sugar combination and respective use thereof, whose purpose is to provide combination of moisturizing and anti wrinkling functions with effect of skin surface forming natural water lock shield, raising skin water content, improving skin elasticity and texture fiber, and softening skin; whose technique scheme comprises by weight: 0.5-10 parts of seaweed multi sugar, 5-50 parts of nerve amide polymer, 5-60 parts of celosia seed extract; the invention yet relates to the seaweed containing multi sugar combination respective use, and belongs to the technical field of cosmetics.
Description
Technical field
The present invention relates to a kind of compositionss, specifically, it is to be related to a kind of compositionss containing Porphyra Polysaccharide, the present invention also relates to
And the application of said composition；Belong to cosmetic field.
Background technology
Temperature change and pressure that air-conditioning, environmental pollution, Seasonal conversion etc. bring, and skin aging, metabolism slow down
Factor all can cause skin excessive water run off, make skin coarse, dim mute, formed dry stricture of vagina, cause many skin problems.Prevent skin
Skin excessive water runs off, and for the health keeping skin barrier function and skin, or even skin beauty outward appearance is all extremely important
's.
Reduce, in order to reach, the purpose that excessive water scatters and disappears, add moisturizing ingredient generally in skin-protection product.Conventional guarantor
Wet composition can be divided into enclosed type, moistening or moisture absorption type two big class.
Enclosed type moisturizing ingredient is the insoluble lipid material of a class, including mineral oil, wax class, silicone oil, plant with dynamic
The fat in thing source and wax, fatty acid, esters, phospholipid and cholesterol, these compositions are by keratodermatitis lipid material
Supplement, form the lubricant film layer that a surface adds, horny layer is wrapped up, the moisture in skin is stopped by sealing process
Lose, prevent moisture evaporation, so that moisture constantly diffuses into horny layer by skin nexine, make horny layer keep certain containing
The water yield.
Moistening or moisture absorption type moisturizing ingredient are that a class is similar to nature moisturizing factor in epidermis and human body protein, polysaccharide etc.
Macromolecular substances, be a kind of moisture added body.Wherein with polysaccharide and ceramide, hyaluronic acid as representative.These compositions lead to
Cross pore to enter inside skin, or carry moisture, or the moisture of not yet loss in skin is wrapped up, so that moisture in skin is obtained
To retain.
After smearing moisture absorption type moisturizing ingredient, the water content of corneocyte rises, and corneocyte is softened, and is conducive to
Nutrient substance is merged with the hydrone in corneocyte, subsequently into skin corium.
Enclosed type moisturizing ingredient easily causes skin allergy, and then, those skilled in the art are placed on moisture absorption type to protect energy
In the research of wet composition, to meet the demand to skin protection safety for the consumer.In recent years, by natural and synthetic source moisture absorption
Type moisturizing ingredient compounding use is increasingly becoming the new direction of cosmetic industry research, but at present will be natural and synthetic source
The product that moisture absorption type moisturizing ingredient compounds can only improve the water content of skin mostly, in moisturizing water lock, improves skin elasticity and anti-
The also very big rooms for improvement of aspect such as wrinkle.
Content of the invention
For the problems referred to above, it is an object of the invention to provide one kind can form water lock barrier in skin surface, improve skin
Water content, improves skin elasticity and texture, makes skin become soft, has moisturizing and the compositionss of crease-resistant effect.
For this reason, first technical scheme that the present invention provides is such：
A kind of compositionss containing Porphyra Polysaccharide, main inclusion following weight parts component：0.5-10 part Porphyra Polysaccharide, 5-50 part
Ceramide polymer, 5-60 part Herba Celosiae argenteae seed extract.
Further, above-mentioned a kind of compositionss containing Porphyra Polysaccharide, described compositionss also include 0.2-10 part Ba Er
Dry lettuce tongue leaf extract.
Further, above-mentioned a kind of compositionss containing Porphyra Polysaccharide, described compositionss also include 0.5-8 part algaroba
Seed extract.
Further, above-mentioned a kind of compositionss containing Porphyra Polysaccharide, described compositionss are by following components in parts by weight
Composition：2-8 part Porphyra Polysaccharide, 10-30 part ceramide polymer, 10-30 part Herba Celosiae argenteae seed extract, 2-5 part Balkan lettuce tongue
Leaf extract, 2-4 part algaroba seed extract.
Further, the preparation method of described Porphyra Polysaccharide is as follows：
1) Thallus Porphyrae dry product is ground into 20-40 mesh coarse powder, adds 95% ethanol of coarse powder weight 5-10 times amount overnight to soak
Remove fat, filter, discard filtrate, collect filtering residue and repeat immersion process twice；
2) will be through step 1) remove fat after filtering residue washed 2-3 time with distilled water immersion, remove water colo(u)r and algae indigo plant egg
In vain；
3) to step 2) it is initially charged filtering residue weight 5-10 times distilled water in the filtering residue that obtains, freeze 10-16h at -10 DEG C, then
Thaw, repeat above-mentioned freeze and thaw operation twice, filter, respectively collection filtrate A and filtering residue；
4) will be through step 3) process the distilled water immersion 2-4h of the filtering residue that obtains filtering residue weight 40-60 times, in temperature 30-
50 DEG C, under conditions of ultrasonic power 300-600W, after extracting 40-80min, filter, repeat above-mentioned distilled water immersion and ultrasonic carry
Extract operation, filters, and merges the filtrate extracted twice, obtains liquor B；
5) by step 3) the filtrate A that obtains and step 4) liquor B that obtains merges, and is first evaporated to the 1/2 of original volume,
Again with 1:1 equal-volume adds 5% solution of trichloroacetic acid, stands 1-3h, centrifugation, takes supernatant, adjusts pH to 6.5-7.0, then plus
Enter 95% ethanol of supernatant volume 2-4 times amount, soaked overnight, precipitate is done through vacuum freezing after absolute ethanol washing 2-4 time
Dry.
Further, above-mentioned a kind of compositionss containing Porphyra Polysaccharide, described Porphyra Polysaccharide is water front temple Porphyra Polysaccharide.
Last technical scheme that the present invention provides is the above-mentioned compositionss containing Porphyra Polysaccharide as skin care product additive
Application.
Compared with prior art, the technical scheme that the present invention provides has following technological merit：
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides are by natural moisture absorption type moisturizing ingredient Porphyra Polysaccharide and people
The moisture absorption type moisturizing ingredient ceramide polymer phase of work synthesis combines, and forms water lock barrier in skin surface, prevents moisture from dissipating
Lose, maintain and adjust the water content of skin, improve skin elasticity and texture simultaneously, make skin become soft and smooth and be more rich in tension force；
Additionally, two kinds of moisture absorption type moisturizing ingredient again with other natural component Herba Celosiae argenteae seed extracts, Balkan lettuce tongue leaf extract and Chang Jiao
Bean seed extract carries out scientific compatibility, effectively improves moisturizing and anti-wrinkle effect.
Specific embodiment
With reference to specific embodiment, the claim of the present invention is described in further detail, but do not constitute right
Any restriction of the present invention.
It should be noted that the raw material employed in the technical scheme of present invention offer, unless otherwise specified, all by often
Rule means are prepared or are bought by commercial channel.
Ceramide polymer purchases that (i.e. Ke Sifa international trade Shanghai company limited, I NC I is entitled in Ke Sifa
Glycerol amide ethanol methyl acrylate/stearyl alcohol methacrylate copolymer)；Herba Celosiae argenteae seed extract is purchased in Xi'an Tianrui
Bioisystech Co., Ltd；Balkan lettuce tongue leaf extract is purchased and is praised business (Chinese) company limited, algaroba seed in big Chang Hua
Extract is purchased in Guangzhou Rong Dao Chemical Co., Ltd..
Embodiment 1
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：The front temple of 0.5g water is purple
Dish polysaccharide, 50g ceramide polymer, 5g Herba Celosiae argenteae seed extract.
Embodiment 2
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：10g Porphyra Polysaccharide,
5g ceramide polymer, 60g Herba Celosiae argenteae seed extract.
Embodiment 3
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：5g Porphyra Polysaccharide,
20g ceramide polymer, 30g Herba Celosiae argenteae seed extract.
Embodiment 4
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：6g water front temple Thallus Porphyrae
Polysaccharide, 10g ceramide polymer, 20g Herba Celosiae argenteae seed extract, 0.2g Balkan lettuce tongue leaf extract.
Embodiment 5
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：4g Porphyra Polysaccharide,
25g ceramide polymer, 25g Herba Celosiae argenteae seed extract, 10g Balkan lettuce tongue leaf extract.
Embodiment 6
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：7g water front temple Thallus Porphyrae
Polysaccharide, 15g ceramide polymer, 15g Herba Celosiae argenteae seed extract, 0.5g algaroba seed extract.
Embodiment 7
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：3g Porphyra Polysaccharide,
40g ceramide polymer, 40g Herba Celosiae argenteae seed extract, 8g algaroba seed extract.
Embodiment 8
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：8g water front temple Thallus Porphyrae
Polysaccharide, 10g ceramide polymer, 30g Herba Celosiae argenteae seed extract, 2g Balkan lettuce tongue leaf extract, 4g algaroba seed extract.
Embodiment 9
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：2g Porphyra Polysaccharide,
30g ceramide polymer, 10g Herba Celosiae argenteae seed extract, 5g Balkan lettuce tongue leaf extract, 2g algaroba seed extract.
Embodiment 10
A kind of compositionss containing Porphyra Polysaccharide that the present invention provides, are grouped into by following weight array：8g Porphyra Polysaccharide,
10g ceramide polymer, 30g Herba Celosiae argenteae seed extract, 2g Balkan lettuce tongue leaf extract, 4g algaroba seed extract.
The preparation method of Thallus Porphyrae (the water front temple Thallus Porphyrae) polysaccharide of the offer in embodiment 1 to 10 is as follows：
1) Thallus Porphyrae (or water front temple Thallus Porphyrae) dry product is ground into 20-40 mesh (preferably 30 mesh) coarse powder, adds coarse powder weight
95% ethanol of 5-10 (preferably 8 times amount) times amount overnight soaks fat, filters, and discards filtrate, collects filtering residue and repeats immersion process
Twice；
2) will be through step 1) remove fat after filtering residue washed 2-3 time with distilled water immersion, remove water colo(u)r and algae indigo plant egg
In vain；
3) to step 2) it is initially charged filtering residue weight 5-10 times (preferably 8 times amount) distilled water in the filtering residue that obtains, freeze at -10 DEG C
Knot 10-16h (preferably 12h), then thaws, repeat above-mentioned freeze and thaw operation twice, filter, respectively collection filtrate A and filtering residue；
4) will be through step 3) process the distilled water immersion 2- of the filtering residue that obtains filtering residue weight 40-60 times (preferably 30 times amount)
4h (preferably 3h), under conditions of temperature 30-50 DEG C (preferably 40 DEG C), ultrasonic power 300-600W (preferably 400W), extracts 40-
After 80min (preferably 40min), filter, repeat above-mentioned distilled water immersion and supersound extraction operation, filter, merging is extracted twice
Filtrate, obtains liquor B；
5) by step 3) the filtrate A that obtains and step 4) liquor B that obtains merges, and is first evaporated to the 1/2 of original volume,
Again with 1:1 equal-volume adds 5% solution of trichloroacetic acid, standing 1-3h (preferably 2h), centrifugation, takes supernatant, adjusts pH to 6.5-
7.0, add 95% ethanol of supernatant volume 2-4 times amount (preferably 3 times amount), soaked overnight, precipitate is washed through dehydrated alcohol
Vacuum lyophilization after washing 2-4 time.
The method that 1 to 10 any one group of compositions of embodiment are applied as skin care product additive is first by Thallus Porphyrae (Shui Qiansi
Thallus Porphyrae) after polysaccharide is uniformly dispersed with a small amount of deionized water dissolving, adds after other materials are uniformly mixed, be added directly to
In skin care item substrate, stir, addition is the 0.5-8% of skin care item gross weight.
Because water front temple Porphyra Polysaccharide is the giant molecule that a kind of molecular weight is about 29MDa, length is about 8 μm, is generation
One of maximum natural polymer in boundary, can form the nanoscale epithelium of exquisiteness on skin, as the barrier of skin, permissible
Stop water loss, make skin from outside stimuluss simultaneously, there is high water-retaining property (5 times of hyaluronic acid), skin can be strengthened
The elasticity of skin, also has functions that crease-resistant simultaneously, can evoke the antigen-reactive in epidermis and corium, and suppression conduction is struvite thin
The histamine release of intracellular cytokine, relaxes allergic dermatitises symptom.
Ceramide polymer is the both effectiveness material of the structure design imitating ceramide, and its network structure can be
Skin horny layer forms the thin film of resistance to water and high flexibility, has good affinity to skin, gives skin barrier function,
There is the hygroscopicity more superior than synthesis ceramide, natural ceramide, skin elasticity and texture can also be improved simultaneously, make
Skin becomes soft and smooth and is more rich in tension force.
Above two composition and Herba Celosiae argenteae seed extract, Balkan lettuce tongue leaf extract and algaroba seed extract scientific compatibility
Afterwards, water lock barrier can be formed in skin surface, effectively improve the water content of skin, make skin become soft, promote skin pair
The absorption of nutrient substance, has moisturizing and crease-resistant effect.
A kind of compositionss containing Porphyra Polysaccharide of present invention offer, in order to better illustrate advantages of the present invention, are provided
Efficacy test：
First, zest test
In order to verify the zest of the present invention, the test sample of embodiment of the present invention 1-10 preparation is sent to third party's detection
Detection skin irritation, to each test sample all with the continuous skin irritation test of 6 Embryo Gallus domesticus, and the going out of the Embryo Gallus domesticus of test group
Blood, blood coagulation and the blood vessel time of melting are above 300 minutes.Result shows, the test sample of above-described embodiment preparation is calculated
Stimulation scoring be zero, illustrate the embodiment of the present invention 1-10 preparation test sample be nonirritant product.
2nd, efficacy test
(1) with regard to the comparative example of efficacy test
Comparative example 1
Contain only emulsion matrix.
Comparative example 2
The a certain commercially available moisturizer bought.
Comparative example 3
Without ceramide polymer, remaining is same as Example 8.
Comparative example 4
Without Porphyra Polysaccharide, remaining is same as Example 8.
(2) with regard to the preparation of test sample
First, by the compositionss of embodiment 2,4,6,8,10, comparative example 3 and comparative example 4, it is added separately to emulsion matrix
In, make moisturizer.
Wherein：The mass ratio 4 of compositionss and emulsion matrix:96.
Described emulsion matrix is moisturizer substrate commonly used in the art, based on emulsion matrix gross mass 100g, each group
Divide and its weight percent such as table 1：
Table 1
Technique：1) A phase is heated with stirring to 80 DEG C about, standby；2) first the deionized water in B phase is heated to 80-90 DEG C,
It is subsequently adding B phase clout, stirring and dissolving homogenizing is to no granule, add the good A phase of pretreatment, after homogenizing 3-5min, insulation
Stirring froth breaking, is cooled to 45 DEG C about, adds C phase, stirs, be cooled to 35 DEG C and obtain final product emulsion matrix.
2nd, moisture test
1st, test population：90 experimenters, age 20-60 year, sex is random, is divided into 9 groups, every group of 10 people.
2nd, method of testing：
Select experimenter's left and right arm cycle labeling successively：Tested region samples group and blank region；Technical staff
Using moisture content of skin test Corneometer CM825 measurement, average, be designated as blank value.Clear through clear water in experimenter
Washed Test sites use sample after 15 minutes, throw off and pat recipient site.Experimenter continuously use cosmetics 0.5h,
After 1h, 2h, 4h, 6h, use moisture content of skin test Corneometer CM825 to measure 5 times by technical staff, average.
Count the numerical value recording, analyze its moisture of skin Changing Pattern.
Test result is shown in Table 2：
Table 2 moisture test result
As can be seen from Table 2, after the moisturizer using interpolation embodiment 10 and 8 compositionss, its moisture is higher than other
The moisturizer of embodiment 2,4,6 preparation and commercially available moisturizer, illustrate in Porphyra Polysaccharide (or water front temple Porphyra Polysaccharide), nerve
On the basis of amide polymer, Herba Celosiae argenteae seed extract are worked in coordination with, work in coordination with Balkan lettuce tongue leaf extract, algaroba seed extract,
The moistening effect reaching is best；The moisture of comparative example 3 and 4 moisturizers is significantly lower than the guarantor of embodiment 2,4,6,8,10 preparation
Wet breast, illustrates that in the present invention, the ceramide polymer adding and Porphyra Polysaccharide rise emphatically in the moistening effect of this compositions
The effect wanted.
Additionally, after the moisturizer prepared using embodiment 10, its moisture situation is combined relatively lower than using embodiment 8
The moisturizer of thing preparation, illustrates that the moistening effect of the water front temple Porphyra Polysaccharide of preparation in this compositions is optimal, better than Porphyra Polysaccharide.
3rd, barrier function test
This test uses percutaneous moisture loss (TEWL) to evaluate the power of skin barrier function.Protective layer of skin is better, moisture content
Content is higher, and the numerical value of skin moisture loss TEWL is lower.
1st, test population：90 experimenters, age 20-60 year, sex is random, is divided into 9 groups, every group of 10 people.
2nd, method of testing：
A. detect first three sky it is desirable to experimenter can not smear any cosmetics, visit in the 1st day TEWL with CK MPA580
Head test 5 times, averages.
B. require experimenter that above-mentioned for 0.1g test sample is applied in about 4cm2Skin on, sooner or later each once, continuously make
With 28 days, disable within the 29th, 30 days product, the 31st day measurement TEWL.
Test result is shown in Table 3：
Table 3 barrier function test result
As can be seen from Table 2, after the moisturizer using interpolation embodiment 10 and 8 compositionss, its skin moisture loss TEWL
Value, less than the moisturizer of other embodiments 2,4,6 preparation and commercially available moisturizer, illustrates in Porphyra Polysaccharide (or water front temple Thallus Porphyrae
Polysaccharide), ceramide polymer, Herba Celosiae argenteae seed extract work in coordination with the basis of, carry with Balkan lettuce tongue leaf extract, algaroba seed
Take thing to work in coordination with, skin barrier function can be effectively increased, reduce scattering and disappearing of moisture of skin；Using the TEWL after embodiment 10 moisturizer
Value is also relatively higher than the moisturizer using the preparation of embodiment 8 compositionss, and the water front temple Porphyra Polysaccharide of preparation in this compositions is described
Effect in setting up skin barrier function is better than Porphyra Polysaccharide.
Additionally, after the moisturizer prepared using comparative example 3 and 4, its TEWL value is higher than embodiment 2,4,6,8,10 preparation
Moisturizer, illustrates that in the present invention, the ceramide polymer adding and Porphyra Polysaccharide can help this compositions preferably to increase skin
Barrier function, plays more preferable water lock effect.
4th, anti-wrinkle effect test
1st, test population：Mean age be 35-50 year 90 women, facial skin elasticity and texture poor, be divided into 9
Group, every group of 10 people.
2nd, method of testing：
(1) first skin elasticity tester (Cutometer dual MPA580) determination experiment portion is used by technical staff
The skin elasticity numerical value before cosmetics is smeared in position, is measured using skin image analysis system (Skin Visiometer SV600)
Test sites smear cosmetics before skin texture degree, every survey five times, average.
(2) every group of experimenter smears test sample in left face, sooner or later smears twice daily, and right face is comparison, does not smear examination
Sample.During experiment, any other cosmetics can not be smeared by experimenter face.
(3) every group of experimenter is continuously using test sample after two months, tests skin elasticity numerical value and skin texture degree
Value, surveys five times for every, averages.
(4) count the numerical value that every group of subject position records every time, analyze its skin elasticity and texture change rule
Rule, so that it is determined that crease-resistant effect.The results are shown in Table shown in 4 and table 5.
Table 4 skin elasticity test result
Table 5 skin texture degree test result
Result above shows, using adding after the moisturizer of embodiment 10 and 8 compositionss, its skin elasticity and texture
Rate of change is significantly higher than the moisturizer of other embodiments 2,4,6 preparation and commercially available moisturizer, illustrates in Porphyra Polysaccharide (or water
Front temple Porphyra Polysaccharide), ceramide polymer, Herba Celosiae argenteae seed extract work in coordination with the basis of, with Balkan lettuce tongue leaf extract, length
Carob seed extract is worked in coordination with, and can be effectively improved skin elasticity and texture, play crease-resistant effect；And embodiment 10 moisturizer
Skin elasticity and texture rate of change also relatively lower than the moisturizer prepared using embodiment 8 compositionss, illustrate using this
In compositionss, the anti-wrinkle effect of water front temple Porphyra Polysaccharide preferably, is higher than the anti-wrinkle effect of general Porphyra Polysaccharide.
Additionally, after the moisturizer prepared using comparative example 3 and comparative example 4, the rate of change of its skin elasticity and texture is low
In the moisturizer of embodiment 2,4,6,8,10 preparation, illustrate that in the present invention, the ceramide polymer adding and Porphyra Polysaccharide can be helped
Help this compositions preferably to improve skin elasticity and texture, play more preferable anti-wrinkle effect.
Additionally, follow-up is carried out after using test sample 1 week, 2 weeks, 3 weeks and 4 weeks to above-mentioned each group experimenter, all instead
Reflect no ill symptomses in use, after use, the symptoms such as facial sufferings, redness, edema, inflammation do not occur yet, occasionally have face
Portion's prurituss, rubescent easy allergy experimenter are reacted after the test sample prepared using this compositions, and prurituss and redness obtain
Take a turn for the better to obvious, illustrate that the compositionss of the present invention have safety, and can effectively alleviate phenomena of cutaneous irritation.
In sum, the present invention Porphyra Polysaccharide, ceramide polymer, Herba Celosiae argenteae seed extract work in coordination with the basis of, with
Balkan lettuce tongue leaf extract, algaroba seed extract are worked in coordination with, and form water lock barrier in skin surface, prevent moisture loss, dimension
Hold and adjust the water content of skin, improve skin elasticity and texture simultaneously, make skin become soft and smooth and be more rich in tension force, there is guarantor
Wet and crease-resistant effect；Moreover it is possible to effectively alleviate phenomena of cutaneous irritation.
Claims (7)
1. a kind of compositionss containing Porphyra Polysaccharide are it is characterised in that mainly include following weight parts component：0.5-10 part Thallus Porphyrae is many
Sugar, 5-50 part ceramide polymer, 5-60 part Herba Celosiae argenteae seed extract.
2. a kind of compositionss containing Porphyra Polysaccharide according to claim 1 are it is characterised in that described compositionss also include
0.2-10 part Balkan lettuce tongue leaf extract.
3. a kind of compositionss containing Porphyra Polysaccharide according to claims 1 or 2 are it is characterised in that described compositionss
Also include 0.5-8 part algaroba seed extract.
4. a kind of compositionss containing Porphyra Polysaccharide according to claim 1 are it is characterised in that described compositionss are by following
The group of weight portion is grouped into：2-8 part Porphyra Polysaccharide, 10-30 part ceramide polymer, 10-30 part Herba Celosiae argenteae seed extract, 2-5
Part Balkan lettuce tongue leaf extract, 2-4 part algaroba seed extract.
5. a kind of compositionss containing Porphyra Polysaccharide according to claim 1 are it is characterised in that the preparation of described Porphyra Polysaccharide
Method is as follows：
1) Thallus Porphyrae dry product is ground into 20-40 mesh coarse powder, adds 95% ethanol of coarse powder weight 5-10 times amount overnight to soak fat,
Filter, discard filtrate, collect filtering residue and repeat immersion process twice；
2) will be through step 1) remove fat after filtering residue washed 2-3 time with distilled water immersion, remove water colo(u)r and phycocyanin；
3) to step 2) it is initially charged filtering residue weight 5-10 times distilled water in the filtering residue that obtains, freeze 10-16h at -10 DEG C, then solve
Freeze, repeat above-mentioned freeze and thaw operation twice, filter, respectively collection filtrate A and filtering residue；
4) will be through step 3) process the distilled water immersion 2-4h of the filtering residue that obtains filtering residue weight 40-60 times, in temperature 30-50
DEG C, under conditions of ultrasonic power 300-600W, after extracting 40-80min, filter, repeat above-mentioned distilled water immersion and supersound extraction
Operation, filters, and merges the filtrate extracted twice, obtains liquor B；
5) by step 3) the filtrate A that obtains and step 4) liquor B that obtains merges, and is first evaporated to the 1/2 of original volume, then with
1:1 equal-volume adds 5% solution of trichloroacetic acid, stands 1-3h, centrifugation, takes supernatant, adjusts pH to 6.5-7.0, adds
95% ethanol of supernatant volume 2-4 times amount, soaked overnight, precipitate is through vacuum lyophilization after absolute ethanol washing 2-4 time.
6. a kind of compositionss containing Porphyra Polysaccharide according to claim 1 are it is characterised in that described Porphyra Polysaccharide is water
Front temple Porphyra Polysaccharide.
7. a kind of compositionss containing Porphyra Polysaccharide described in claim 1 are as the application of skin care product additive.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611013549.XA CN106389223A (en) | 2016-11-18 | 2016-11-18 | Violate seaweed containing multi sugar combination and respective use thereof |
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