CN103919704A - Anti-aging essence - Google Patents
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- CN103919704A CN103919704A CN201410176978.3A CN201410176978A CN103919704A CN 103919704 A CN103919704 A CN 103919704A CN 201410176978 A CN201410176978 A CN 201410176978A CN 103919704 A CN103919704 A CN 103919704A
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Abstract
The invention discloses anti-aging essence, and relates to the field of processing technology of cosmetics in daily-use chemical industry. The anti-aging essence is prepared from the following raw materials: A components: polyethylene glycol, propylene glycol, glycerin and butylene glycol; B components: camellia oil, hydrogenated castor oil, C12-20 alkyl glucoside, glyceryl stearate and octadecanol; C components: methyl paraben, Casson and imidazolidinyl urea; D components: coenzyme Q10, squalane and sodium pyrrolidonecarboxylate; E components: saxifrage extracting solution, centella extracting solution; citric acid; the balance of deionized water, and 100 parts of raw materials are provided in total; the preparation process is as follows: (1) mixing the A components; (2) mixing the B components; (3) mixing the A components and the B components; (4) mixing the A components, the B components and the C components; (5) mixing all raw materials; (6) aging. The anti-aging essence both has a good moisturizing and nourishing effect and has an anti-aging function, and is suitable for crowds with different skins and anti-aging demands.
Description
Technical field
The present invention relates to the cosmetics processing technique field in daily-use chemical industry, particularly a kind of defying age essence.
Technical background
Skin aging is a progressive physiological process, is also the result of the various factors comprehensive functions such as heredity, environment, social mentality.Along with the raising of people's living standard, more and more higher to the functional requirement of skin care item, the skin care item that possess defying age effect also emerge in an endless stream.Essence, is a kind of skin care item that are added with concentrated high nutritional labeling, according to the specific aim of its formula, have anti-ageing, crease-resistant, compact, moisturizing, Bearberry Extract.Special profit as instant in the Est é e Lauder in the fashionable world is repaired elite, the compound elite of sisley polywater, the perfect essence of Jason Natural esterification C whitening anti-aging etc.In these product compositions, added multiple concentrated elite, also added more antiseptic simultaneously, the especially easily antiseptic of sensitization, as dibenzylatiooluene and benzyl alcohol.Therefore, seek safer, milder, more effective skin care item are very urgent.As Chinese patent (number of patent application is 201210455923.7) " a kind of Aloe essential liquid ", it is by forming by the raw material of proportion by weight below: plant essence liquid 70%-80%, aloe juice 2%-4%, arbutin 0.5%-1%, glycerol 1%-3%, Herba Centellae 1.5%-3%, hyaluronic acid 0.2%-0.5%, collagen protein 0.1%-0.5%, vitamin e 0.2%-0.5%, amino acid 0.2%-0.5%, all the other are glycerol; This invention can be dredged the pore that is obstructed, and bactericidal antiphlogistic supplements the required moisture of skin, strengthens cell viability and elasticity comprehensively, increases tight skin density, removes the dim metabolite of epidermis.
Technology contents
The object of the present invention is to provide a kind of existing good moisturizing, moisturizing effect, there is again the skin-protection product of senile-resistant efficacy.
For realizing its object, the technical solution used in the present invention is a kind of defying age essence of invention:
(i) be, to be prepared from by following raw material by weight:
A component: Polyethylene Glycol 6-9 part, propylene glycol 4-8 part, glycerol 5-12 part, butanediol 1-3 part;
B component: Oleum Camelliae 4-6 part, castor oil hydrogenated 1-4 part, C12-20 alkyl androstanediol 1-5 part, glycerol stearic acid 1-5 part, octadecanol 0.5-3 part;
C component: methyl hydroxybenzoate 0.05-0.15 part, Kazon 0.2-0.4 part, imidazolidinyl urea 0.2-0.3 part;
D component: coenzyme Q10 0.1-0.5 part, squalane 1-3 part, pyrrolidone sodium carboxylate 1-7 part;
E component: Herba Saxifragae extracting solution 12-20 part, Herba Centellae extracting solution 6-12 part;
Citric acid: 0.01-0.1 part;
Surplus is deionized water, adds up to 100 parts;
(ii), its preparation process is as follows:
1., A component is mixed: all raw materials of A component are joined in deionized water, stir 2-4min with the rotating speed of 2000r/min, then, be heated to 70-80 DEG C by the programming rate of 2-4 DEG C/min, maintenance 8-12min, becomes A component compound, for subsequent use;
2., B component is mixed: by all raw material mix homogeneously of B component, stir 2-4min with the rotating speed of 2000r/min, then, be heated to 60-80 DEG C by the programming rate of 2-4 DEG C/min, maintenance 8-12min, becomes B component compound, for subsequent use;
3., AB group is mixed: A component compound for subsequent use is mixed with B component compound, rotating speed with 500r/min under 60-80 DEG C of condition stirs, pre-emulsification 10-20min, then, with the speed slow cooling of 1-2 DEG C/min during to 50-70 DEG C, stir 5-10min with the rotating speed of 3000r/min again, more successively after 20-40MPa high pressure homogenize 5-10min, 5-15Mpa low pressure homogenizing 5-10min process, vacuum outgas under 0.1-0.5Mpa condition, become AB component compound, for subsequent use;
4., ABC organizes mixing: it is 50-70 DEG C that AB component compound for subsequent use is kept to temperature, adds all raw materials of C component under constant temperature, and mix homogeneously becomes ABC group compound, for subsequent use;
5., entirely mix: ABC group compound for subsequent use is cooled to 40-60 DEG C from the 50-70 DEG C of speed with 1-2 DEG C/min, add all raw materials of D component and E component, add again citric acid to regulate pH value to 6-7, then, stir and be cooled to 25-35 DEG C with the speed of 1000r/min, become full batch mixing, for subsequent use;
6., ageing: full batch mixing for subsequent use is placed to ageing 25-35h at 20-25 DEG C, defying age essence.
The technical scheme of its optimization is to be prepared from by following raw material by weight:
A component: 6 parts of Polyethylene Glycol, 7 parts of propylene glycol, 12 parts of glycerol, 1 part of butanediol;
B component: 4 parts of Oleum Camelliae, 1 part of castor oil hydrogenated, 1 part of C12-20 alkyl androstanediol, 2 parts of glycerol stearic acid, 1.5 parts of octadecanol;
C component: 0.05 part of methyl hydroxybenzoate, 0.2 part of Kazon, 0.3 part of imidazolidinyl urea;
D component: 0.1 part of coenzyme Q10,2.5 parts of squalanes, 3 parts of pyrrolidone sodium carboxylates;
E component: 16 parts of Herba Saxifragae extracting solution, 10 parts of Herba Centellae extracting solution;
Citric acid: 0.02 part;
Surplus is deionized water, adds up to 100 parts.
Described Oleum Camelliae is commercially available refining Oleum Camelliae.Also can adopt following method to be prepared from: by commercially available refining Oleum Camelliae, be heated to 45-55 DEG C, constant temperature keeps 15-25min; Then, be cooled to 3-5 DEG C, growing the grain 10-15h; Under 0-4 DEG C of cryogenic conditions, vacuum filtration, isolates liquid fat and solid lipid again, collects the liquid fat of gained, is required Oleum Camelliae.
Described Herba Saxifragae extracting solution is that Herba Saxifragae herb deionized water is cleaned up, and squeezes its juice, gained after filtering.Also can be prepared from as follows: Herba Saxifragae herb deionized water is cleaned up, squeeze its juice, after filtration, obtain respectively filtrate A and residual filtering residue; In residual filtering residue, add the ethanol that 1.5-2.5 times of weight, volumetric concentration are 45-55% again, soak at normal temperatures and pressures 10-15 hour, filter, obtain soak; Again soak is adopted to the method for concentrating under reduced pressure, be concentrated into the half of original volume, obtain liquor B; Merging filtrate A and liquor B, be required Herba Saxifragae extracting solution.Above-mentioned Herba Saxifragae used is to adopt fresh Herba Saxifragae herb.
Described Herba Centellae extracting solution is that Herba Centellae is cleaned up, and adds pure water according to the part by weight of solid-liquid ratio 1:5, boils and extracts 1 hour, gained after filtering.Also can be prepared from as follows: Herba Centellae deionized water is cleaned up, add deionized water according to the part by weight of solid-liquid ratio 1:10-20, be heated to 90-110 DEG C, constant temperature extracts 1-3 hour, filter, respectively extracting solution and filtering residue; Press again the part by weight of solid-liquid ratio 1:10-20, in filtering residue, add deionized water, boil and extract 0.5-2 hour, filter, obtain secondary raffinate; Merge extracted twice liquid, and adopt the method for vacuum concentration, be concentrated into the half of original volume, be required Herba Centellae extracting solution.
Defying age essence of the present invention, the main raw material(s) adopting comprises:
A, Polyethylene Glycol: i.e. PEG-600 is a kind of water-soluble polymer of nonionic, stable chemical nature, in the present invention as lubricant and wetting agent;
B, propylene glycol: coordinate as wetting agent with glycerol in the present invention;
C, glycerol: i.e. glycerol, in the present invention as wetting agent;
D, butanediol: having another name called 1,3-dihydroxy butane, is the one of polyhydric alcohol, in the present invention as wetting agent and solvent;
E, glyceryl stearate: in the present invention as emulsifying agent;
F, Oleum Camelliae: faint yellow transparent liquid, it is the oils and fats that is squeezed gained by the kernel (Camellia oleifera Abel) of oil tea section plant oil tea, containing more than 85% unsaturated fatty acid, is the effective ingredient in the present invention, uses as softening agent;
G, castor oil hydrogenated: can promote dispersed in product of oil phase maintenance composition, in the present invention as solubilizing agent;
H, C12-20 alkyl androstanediol: a kind of non-ionic surface active agent of low stimulation, uses as emulsifying agent, emulsion stabilizer in the present invention;
I, octadecanol: be the base stock of cosmetics cream frost, emulsion, there is the effect of thickening Emulsion, use as emulsion stabilizer in the present invention;
J, citric acid: in order to prepare buffer solution, keep the pH value of astringent system stable, in the present invention as buffer agent;
K, coenzyme Q10: be a kind of powerful antioxidant; can suppress lipid peroxidation; reduce the generation of free radical; protection SOD active center and structure thereof are avoided Free radicals injury; improve the enzymatic activitys such as the interior SOD of body; the apoptosis of inhibited oxidation stress induction, has the effect of significant antioxidation, slow down aging.
L, squalane: the Squalene extracting from deepwater shark liver makes through hydrogenation, have good antioxygenic property, the good affine skin of energy, and hypoallergenic and low stimulation, and can accelerate the absorption of skin to other active component;
M, pyrrolidone sodium carboxylate (PCA-Na): claiming again sodium pyroglutamate, is the main component of nature moisturizing factor NMF in skin, has very strong moisture-keeping function, long-term moisture retention is strong, to skin as mild as a dove, in the present invention as wetting agent;
N, Kazon: be called for short isothiazolone, soluble in water and low-carbon alcohols, the best pH value 4-8 that uses, toxicity is low, has advantages of that antibacterial action is in extensive range and antibacterial effect is strong, and to be used in conjunction with effect better with methyl hydroxybenzoate;
O, methyl hydroxybenzoate: have another name called methyl parahydroxybenzoate, for white crystalline powder or colourless crystallization, be soluble in alcohol, ether and acetone, have phenolic hydroxyl structure, and antibacterium performance is superior;
P, imidazolidinyl urea: white powder, very easily water-soluble, in the present invention as antiseptic;
Q, Herba Saxifragae extracting solution: extract from saxifragaceae plant Herba Saxifragae (Saxifraga stolonifera Curt.), micro-bitter, acrid, cold, dispels the wind, heat clearing away, removing pathogenic heat from blood and toxic substance from the body.
R, Herba Centellae extracting solution: extract from samphire Herba Centellae (Centella asiatica (L.) Urban) nature and flavor: bitter, acrid, cold, return liver,spleen,kidney warp, energy heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Herba Centellae extracting solution contains abundant asiaticoside (Asiaticoside), there are the important function such as the collagenocyte of promotion is synthetic and neovascularity generates, the growth of stimulation granulation, and there is certain anti-oxidation function, can suppress free radical activity, improve skin blood circulation, promote skin cell regeneration.
Defying age essence of the present invention, Oleum Camelliae and moisturizing composition pyrrolidone sodium carboxylate are added, and adopt coenzyme Q10, squalane, Herba Saxifragae extracting solution and Herba Centellae extracting solution are main defying age composition, pin on the one hand moisture of skin, increase skin elasticity, in the present invention, be added with coenzyme Q10 on the other hand, can penetrate into the oxidation reaction that skin growth layer weakens photon, under the assistance of fertility alcohol, can start specific phosphorylated tyrosine kinases, prevent the oxidative damage of DNA, suppress the expression of application on human skin fibroblast Collagenase under irradiation under ultraviolet ray, protection skin avoids damage, smear the skin care item that contain coenzyme Q10, can increase the absorption of cell to coenzyme Q10, thereby reduce the formation of wrinkle, the anti-oxidation function that Herba Saxifragae extracting solution and Herba Centellae extracting solution possess, can delaying skin aging.Therefore, defying age essence of the present invention, not only has good moisturizing, moisturizing effect, and the defying age ability that it is powerful also can provide for skin is anti-ageing power endlessly.
Defying age essence of the present invention, detection index and the functional evaluation of its product (taking embodiment five as sample) are as follows:
One, sanitary index and sense organ physical and chemical index
The every sanitary index of defying age essence of the present invention and organoleptic indicator all meet the standard of QB/T2660-2004 astringent after testing.
Following table 1 is sanitary index and the sense organ physical and chemical index of defying age essence of the present invention.
The sanitary index of table 1 defying age essence of the present invention and sense organ physical and chemical index
Two, functional evaluation
1, evaluate principle
ORAC is the abbreviation of oxyradical absorbability (Oxygen Radical Absorption Capacity), and oxyradical absorbability is called again oxidation resistance.ORAC reaction is an oxidizing process that classical hydrogen atom shifts.Under experimental condition, the AAPH of a part loses a part nitrogen, generates two molecule AAPH free radicals (1).In air, AAPH free radical and the oxygen reaction of generation, generate metastable peroxy radical ROO (2).The degree that weakens of fluorescent agent shows that peroxy radical is to its destructiveness.Under the condition that has antioxidant content to exist, ROO obtains a hydrogen atom from antioxidant content, generates ROOH and a stable antioxidant free radical ArO (3).
R-N＝N-R→2R·+N
2 (1)
R·+O2→ROO· (2)
ROO·+ArOH→ArO·+ROOH (3)
Set two groups of contrasts, the Free Radical contrast (+AAPH) when not adding the FL fluorescence Natural Attenuation contrast (AAPH) of free radical and thering is no antioxidant.The oxidation resistance of sample and fluorescence decline curve under Free Radical to delay part area directly related.
2, measurement result
Area poor under the fluorescence decline curve of Free Radical when adding fluorescence decline curve area under defying age essence of the present invention effect and existing without defying age essence of the present invention, the protected area that the decay part area Net AUC of fluorescence quenching curve is antioxidant.The oxygen radical removing ability ORAC value of antioxidant, is called again the ORAC of antioxidant, is to draw compared with the protected area of fluorescence decline curve and the protected area of standard antioxygen material.ORAC value is with Trolox equivalent/μ mol, and μ mol Trolox equivalent/ml and μ mol Trolox equivalent/mg expresses.Its computing formula is:
ORAC value=[(AUC
sample-AUC+
aAPH)/AUG
trolox-AUC+
aAPH] × (molarity of Trolox/molarity of sample)
The ORAC value result of defying age essence of the present invention is 12 μ mol TE/ml.
3, in-vitro evaluation
Defying age essence of the present invention, its senile-resistant efficacy, through in-vitro evaluation (in vitro) test, proves that it has antioxidative effect.
Defying age essence of the present invention, in-vitro evaluation test is as follows:
(i), test crowd
(1), the age is between 25-40 year;
, healthy, rule of life;
(3), without dermatosis and allergies.
According to mentioned above principle, determine testing crew 40 people,
(ii), test method
(1), skin moisture content assay method:
Test environment temperature is 25 DEG C, and relative humidity (Relative Humidity) is 60-90%, and before measuring, 10min exposes tested position, allows examinee keep tranquil simultaneously.On the forearm of left and right, respectively mark the square Experimental Area of 4 4cm × 4cm, and Experimental Area is numbered to X1, X2, X3, X4, Y1, Y2, Y3, Y4, left arm is as the test section of smearing defying age essence of the present invention, and the symmetrical region of right arm is blank district, uses the mixture of A, B, C component.Use moisture of skin analyzer difference determination test region 5 times, record result; According to 1ml/cm
2consumption smear this money essence and be massaged into gently after absorption, in the time of 15min, 30min, 60min, 120min and 240min, use moisture of skin tester to measure respectively, test out keratodermatitis moisture content value (representing with a.u.), and record test result.In order better to evaluate the data obtained, introduce the concept of skin moisture-keeping increase rate, be about to each difference that detects moisture content value while using the moisture content value that records after product with spread product not, moisture content value during divided by spread product not, the result obtaining is skin moisture-keeping increase rate.Use different time points moisture of skin percentage change after this money essence by calculating, can well evaluate product and whether there is moisture retention and moistening effect.
(2), skin elasticity assay method:
Tester 40 people, on the forearm of left and right, respectively mark the square Experimental Area of 4 4cm × 4cm, and by Experimental Area numbering, left arm is as the test section of smearing defying age essence of the present invention, the symmetrical region of right arm is blank district, uses the mixture of A, B, C component.Smear this money essence according to the consumption of 1ml/cm and be massaged into gently after absorption, in the time of 30min, 60min, 120min, 240min and 480min, use skin elasticity tester to measure respectively test section and check plot.In order to evaluate better the data of gained, introduce the concept of skin elasticity increase rate, be about to each the poor of skin elasticity value while using the skin elasticity value that records after product with spread product not that detect, then skin elasticity value during divided by spread product not, acquired results is skin elasticity value increase rate.Use the percentage ratio of this money essence in different time points skin skin elasticity value by calculating, can evaluate well product and whether there is the skin elasticity of maintenance effect.
(3), result of the test
Table 2 skin test result
As shown in Table 2, use defying age essence of the present invention, can improve significantly the moisturizing rate of skin, and there is the effect that improves skin elasticity.Therefore, defying age essence of the present invention, has good moist maintenance to use to skin.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.Explanation is below the mode exemplifying, but protection scope of the present invention is not limited to this.
Embodiment mono-:
The defying age essence of the present embodiment, its preparation process comprises:
(i), raw material is prepared
1, get the raw materials ready: take off respectively by weight row raw material for standby:
A component: 6 parts of Polyethylene Glycol, 4 parts of propylene glycol, 9 parts of glycerol, 1 part of butanediol;
B component: 4 parts of Oleum Camelliae, 2 parts of castor oil hydrogenated, 3 parts of C12-20 alkyl androstanediol, 1 part of glycerol stearic acid, 0.5 part of octadecanol;
C component: 0.05 part of methyl hydroxybenzoate, 0.2 part of Kazon, 0.2 part of imidazolidinyl urea;
D component: 0.1 part of coenzyme Q10,1 part of squalane, 1 part of pyrrolidone sodium carboxylate;
E component: 12 parts of Herba Saxifragae extracting solution, 6 parts of Herba Centellae extracting solution;
Citric acid: 0.02 part;
Surplus is deionized water, adds up to 100 parts;
2, raw material processing
1., Oleum Camelliae processing: by commercially available refining Oleum Camelliae, be heated to 50 DEG C, constant temperature keeps 20min; Then, be cooled to 4 DEG C, growing the grain 12h; Under 0-4 DEG C of cryogenic conditions, vacuum filtration, isolates liquid fat and solid lipid again, collects the liquid fat of gained, is required Oleum Camelliae, for subsequent use;
2., Herba Saxifragae extracting solution preparation: deionized water for Herba Saxifragae herb (fresh) (note: this deionized water is not counted in raw material total amount) is cleaned up, squeeze its juice, after filtration, obtain respectively filtrate A and residual filtering residue; In residual filtering residue, add the ethanol that 2 times of weight, volumetric concentration are 50% again, soak at normal temperatures and pressures 12 hours, filter, obtain soak; Again soak is adopted to the method for concentrating under reduced pressure, be concentrated into the half of original volume, obtain liquor B; Merging filtrate A and liquor B, be required Herba Saxifragae extracting solution, for subsequent use;
3., Herba Centellae extracting solution preparation: deionized water for Herba Centellae (dry product) (note: this deionized water is not counted in raw material total amount) is cleaned up, part by weight according to solid-liquid ratio 1:15 adds deionized water, be heated to 100 DEG C, constant temperature extracts 2 hours, filter, respectively extracting solution and filtering residue; Press again the part by weight of solid-liquid ratio 1:15, in filtering residue, add deionized water, boil and extract 1 hour, filter, obtain secondary raffinate; Merge extracted twice liquid, and adopt the method for vacuum concentration, be concentrated into the half of original volume, be required Herba Centellae extracting solution, for subsequent use;
(ii), its preparation process is as follows:
1., A component is mixed: all raw materials of A component are joined in deionized water, stir 3min with the rotating speed of 2000r/min, then, be heated to 70-80 DEG C by the programming rate of 3 DEG C/min, maintenance 10min, becomes A component compound, for subsequent use;
2., B component is mixed: by all raw material mix homogeneously of B component, stir 3min with the rotating speed of 2000r/min, then, be heated to 60-80 DEG C by the programming rate of 3 DEG C/min, maintenance 10min, becomes B component compound, for subsequent use;
3., AB group is mixed: A component compound for subsequent use is mixed with B component compound, rotating speed with 500r/min under 80 DEG C of conditions stirs, pre-emulsification 15min, then, with the speed of 1-2 DEG C/min from 80 DEG C of slow coolings to 70 DEG C, stir 5min with the rotating speed of 3000r/min again, more successively after 20MPa high pressure homogenize 5min, 5Mpa low pressure homogenizing 5min process, vacuum outgas under 0.5Mpa condition, become AB component compound, for subsequent use;
4., ABC organizes mixing: AB component compound for subsequent use is cooled to 60 DEG C from 70 DEG C, adds all raw materials of C component, mix homogeneously, becomes ABC group compound, for subsequent use;
5., entirely mix: ABC for subsequent use group compound is cooled to 50 DEG C from 60 DEG C, adds all raw materials of D component and E component, then add citric acid to regulate pH value to 6-7, then, stir and be cooled to 25-35 DEG C with the speed of 1000r/min, become full batch mixing, for subsequent use;
6., ageing: full batch mixing for subsequent use is placed to ageing 30h at 20-25 DEG C, defying age essence.
When the defying age essence of the present embodiment uses, suitablely after clean face skin, use astringent, then get appropriate defying age essence and be applied on the face, pat gently and promote to absorb.Notice that each use should not be excessive, also should not in the irritated situation of skin, use.
Embodiment bis-:
The defying age essence of the present embodiment, its preparation process comprises:
(i), raw material is prepared
1, get the raw materials ready: take off respectively by weight row raw material for standby:
A component: 7 parts of Polyethylene Glycol, 6 parts of propylene glycol, 8 parts of glycerol, 1.5 parts of butanediols;
B component: 4.5 parts of Oleum Camelliae, 2 parts of castor oil hydrogenated, 4 parts of C12-20 alkyl androstanediol, 2.5 parts of glycerol stearic acid, 1.5 parts of octadecanol;
C component: 0.08 part of methyl hydroxybenzoate, 0.3 part of Kazon, 0.2 part of imidazolidinyl urea;
D component: 0.2 part of coenzyme Q10,1.75 parts of squalanes, 3 parts of pyrrolidone sodium carboxylates;
E component: 15 parts of Herba Saxifragae extracting solution, 8 parts of Herba Centellae extracting solution;
Citric acid: 0.03 part;
Surplus is deionized water, adds up to 100 parts;
Other is identical with embodiment mono-.
Embodiment tri-:
The defying age essence of the present embodiment, its preparation process comprises:
(i), raw material is prepared
1, get the raw materials ready: take off respectively by weight row raw material for standby:
A component: 8 parts of Polyethylene Glycol, 8 parts of propylene glycol, 6.5 parts of glycerol, 2 parts of butanediols;
B component: 5 parts of Oleum Camelliae, 3 parts of castor oil hydrogenated, 5 parts of C12-20 alkyl androstanediol, 3.5 parts of glycerol stearic acid, 2.5 parts of octadecanol;
C component: 0.11 part of methyl hydroxybenzoate, 0.4 part of Kazon, 0.3 part of imidazolidinyl urea;
D component: 0.3 part of coenzyme Q10,2.5 parts of squalanes, 5 parts of pyrrolidone sodium carboxylates;
E component: 18 parts of Herba Saxifragae extracting solution, 10 parts of Herba Centellae extracting solution;
Citric acid: 0.02 part;
Surplus is deionized water, adds up to 100 parts;
Other is identical with embodiment mono-.
Embodiment tetra-:
The defying age essence of the present embodiment, its preparation process comprises:
(i), raw material is prepared
1, get the raw materials ready: take off respectively by weight row raw material for standby:
A component: 9 parts of Polyethylene Glycol, 8 parts of propylene glycol, 5 parts of glycerol, 3 parts of butanediols;
B component: 6 parts of Oleum Camelliae, 4 parts of castor oil hydrogenated, 5 parts of C12-20 alkyl androstanediol, 5 parts of glycerol stearic acid, 3 parts of octadecanol;
C component: 0.15 part of methyl hydroxybenzoate, 0.4 part of Kazon, 0.3 part of imidazolidinyl urea;
D component: 0.5 part of coenzyme Q10,3 parts of squalanes, 7 parts of pyrrolidone sodium carboxylates;
E component: 20 parts of Herba Saxifragae extracting solution, 12 parts of Herba Centellae extracting solution;
Citric acid: 0.01 part;
Surplus is deionized water, adds up to 100 parts;
Other is identical with embodiment mono-.
Embodiment five:
The defying age essence of the present embodiment, its preparation process comprises:
(i), raw material is prepared
1, get the raw materials ready: take off respectively by weight row raw material for standby:
A component: 6 parts of Polyethylene Glycol, 7 parts of propylene glycol, 12 parts of glycerol, 1 part of butanediol;
B component: 4 parts of Oleum Camelliae, 1 part of castor oil hydrogenated, 1 part of C12-20 alkyl androstanediol, 2 parts of glycerol stearic acid, 1.5 parts of octadecanol;
C component: 0.05 part of methyl hydroxybenzoate, 0.2 part of Kazon, 0.3 part of imidazolidinyl urea;
D component: 0.1 part of coenzyme Q10,2.5 parts of squalanes, 3 parts of pyrrolidone sodium carboxylates;
E component: 16 parts of Herba Saxifragae extracting solution, 10 parts of Herba Centellae extracting solution;
Citric acid: 0.02 part;
Surplus is deionized water, adds up to 100 parts;
Other is identical with embodiment mono-.
Defying age essence of the present invention, the crowd who is suitable for different skin quality, all ages and classes uses.
Claims (5)
1. a defying age essence, is characterized in that:
(i) be, to be prepared from by following raw material by weight:
A component: Polyethylene Glycol 6-9 part, propylene glycol 4-8 part, glycerol 5-12 part, butanediol 1-3 part;
B component: Oleum Camelliae 4-6 part, castor oil hydrogenated 1-4 part, C12-20 alkyl androstanediol 1-5 part, glycerol stearic acid 1-5 part, octadecanol 0.5-3 part;
C component: methyl hydroxybenzoate 0.05-0.15 part, Kazon 0.2-0.4 part, imidazolidinyl urea 0.2-0.3 part;
D component: coenzyme Q10 0.1-0.5 part, squalane 1-3 part, pyrrolidone sodium carboxylate 1-7 part;
E component: Herba Saxifragae extracting solution 12-20 part, Herba Centellae extracting solution 6-12 part;
Citric acid: 0.01-0.1 part;
Surplus is deionized water, adds up to 100 parts;
(ii), its preparation process is as follows:
1., A component is mixed: all raw materials of A component are joined in deionized water, stir 2-4min with the rotating speed of 2000r/min, then, be heated to 70-80 DEG C by the programming rate of 2-4 DEG C/min, maintenance 8-12min, becomes A component compound, for subsequent use;
2., B component is mixed: by all raw material mix homogeneously of B component, stir 2-4min with the rotating speed of 2000r/min, then, be heated to 60-80 DEG C by the programming rate of 2-4 DEG C/min, maintenance 8-12min, becomes B component compound, for subsequent use;
3., AB group is mixed: A component compound for subsequent use is mixed with B component compound, rotating speed with 500r/min under 60-80 DEG C of condition stirs, pre-emulsification 10-20min, then, with the speed slow cooling of 1-2 DEG C/min during to 50-70 DEG C, stir 5-10min with the rotating speed of 3000r/min again, more successively after 20-40MPa high pressure homogenize 5-10min, 5-15Mpa low pressure homogenizing 5-10min, vacuum outgas under 0.1-0.5Mpa condition, become AB component compound, for subsequent use;
4., ABC organizes mixing: it is 50-70 DEG C that AB component compound for subsequent use is kept to temperature, adds all raw materials of C component under constant temperature, and mix homogeneously becomes ABC group compound, for subsequent use;
5., entirely mix: ABC group compound for subsequent use is cooled to 40-60 DEG C from the 50-70 DEG C of speed with 1-2 DEG C/min, add all raw materials of D component and E component, add again citric acid to regulate pH value to 6-7, then, stir and be cooled to 25-35 DEG C with the speed of 1000r/min, become full batch mixing, for subsequent use;
6., ageing: full batch mixing for subsequent use is placed to ageing 25-35h at 20-25 DEG C, defying age essence.
2. defying age essence according to claim 1, it is characterized in that being prepared from by following raw material by weight:
A component: 6 parts of Polyethylene Glycol, 7 parts of propylene glycol, 12 parts of glycerol, 1 part of butanediol;
B component: 4 parts of Oleum Camelliae, 1 part of castor oil hydrogenated, 1 part of C12-20 alkyl androstanediol, 2 parts of glycerol stearic acid, 1.5 parts of octadecanol;
C component: 0.05 part of methyl hydroxybenzoate, 0.2 part of Kazon, 0.3 part of imidazolidinyl urea;
D component: 0.1 part of coenzyme Q10,2.5 parts of squalanes, 3 parts of pyrrolidone sodium carboxylates;
E component: 16 parts of Herba Saxifragae extracting solution, 10 parts of Herba Centellae extracting solution;
Citric acid: 0.02 part;
Surplus is deionized water, adds up to 100 parts.
3. defying age essence according to claim 1 and 2, is characterized in that, described Oleum Camelliae is to be prepared from as follows: by commercially available refining Oleum Camelliae, be heated to 45-55 DEG C, constant temperature keeps 15-25min; Then, be cooled to 3-5 DEG C, growing the grain 10-15h; Under 0-4 DEG C of cryogenic conditions, vacuum filtration, isolates liquid fat and solid lipid again, collects the liquid fat of gained, is required Oleum Camelliae.
4. defying age essence according to claim 1 and 2, is characterized in that, described Herba Saxifragae extracting solution is to be prepared from as follows: Herba Saxifragae herb is cleaned up with deionized water, squeeze its juice, after filtration, obtain respectively filtrate A and residual filtering residue; In residual filtering residue, add the ethanol that 1.5-2.5 times of weight, volumetric concentration are 45-55% again, soak at normal temperatures and pressures 10-15 hour, filter, obtain soak; Again soak is adopted to the method for concentrating under reduced pressure, be concentrated into the half of original volume, obtain liquor B; Merging filtrate A and liquor B, be required Herba Saxifragae extracting solution.
5. defying age essence according to claim 1 and 2, it is characterized in that, described Herba Centellae extracting solution is to be prepared from as follows: Herba Centellae is cleaned up with deionized water, part by weight according to solid-liquid ratio 1:10-20 adds deionized water, be heated to 90-110 DEG C, constant temperature extracts 1-3 hour, filter, respectively extracting solution and filtering residue; Press again the part by weight of solid-liquid ratio 1:10-20, in filtering residue, add deionized water, boil and extract 0.5-2 hour, filter, obtain secondary raffinate; Merge extracted twice liquid, and adopt the method for vacuum concentration, be concentrated into the half of original volume, be required Herba Centellae extracting solution.
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| CN106333917A (en) * | 2016-10-09 | 2017-01-18 | 上海兰葹生物科技有限公司 | Dendrobium nobile skin regeneration promotion combination essence |
| CN106860083A (en) * | 2017-01-19 | 2017-06-20 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment anti-aging Essence |
| CN106860084A (en) * | 2017-01-19 | 2017-06-20 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment anti-aging Essence |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104523530A (en) * | 2015-01-09 | 2015-04-22 | 湖南新金浩茶油股份有限公司 | Anti-aging facial mask and preparation method thereof |
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| CN106333917A (en) * | 2016-10-09 | 2017-01-18 | 上海兰葹生物科技有限公司 | Dendrobium nobile skin regeneration promotion combination essence |
| CN106860083A (en) * | 2017-01-19 | 2017-06-20 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment anti-aging Essence |
| CN106860084A (en) * | 2017-01-19 | 2017-06-20 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment anti-aging Essence |
| CN106860258A (en) * | 2017-01-19 | 2017-06-20 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment anti-aging Essence |
| CN108078857A (en) * | 2018-01-22 | 2018-05-29 | 尹淑珍 | A kind of anti crease and anti senile old essence lotion and preparation method thereof |
| CN108498445A (en) * | 2018-06-26 | 2018-09-07 | 四川自然菲科技有限公司 | A kind of novel anti-aging type Essence |
| CN111166707A (en) * | 2020-01-19 | 2020-05-19 | 广州市柏姿生物科技有限公司 | Facial anti-aging repairing and nursing composition and preparation method and application thereof |
| CN111166707B (en) * | 2020-01-19 | 2022-04-22 | 广州市柏姿生物科技有限公司 | Facial anti-aging repairing and nursing composition and preparation method and application thereof |
| CN111700847A (en) * | 2020-07-22 | 2020-09-25 | 广州清淞泉生物科技有限公司 | Composition for treating dark eye circles by synergistic laser, eye essence and preparation method |
| CN111700847B (en) * | 2020-07-22 | 2020-12-22 | 广州杨森药业有限公司 | Composition for treating dark eye circles by synergistic laser, eye essence and preparation method |
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