CN106389205A - Mouthwash with sodium copper chlorophyllin - Google Patents
Mouthwash with sodium copper chlorophyllin Download PDFInfo
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- CN106389205A CN106389205A CN201610928857.9A CN201610928857A CN106389205A CN 106389205 A CN106389205 A CN 106389205A CN 201610928857 A CN201610928857 A CN 201610928857A CN 106389205 A CN106389205 A CN 106389205A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4993—Derivatives containing from 2 to 10 oxyalkylene groups
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/604—Alkylpolyglycosides; Derivatives thereof, e.g. esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/26—Optical properties
- A61K2800/262—Transparent; Translucent
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Abstract
The invention belongs to the technical field of daily-use chemical products and relates to mouthwash with sodium copper chlorophyllin. The mouthwash with sodium copper chlorophyllin comprises 1.5-2.5% of arabian jasmine flower extracts, 0.5-1.5% of lotus leaf extracts, 0.01-0.3% of the sodium copper chlorophyllin, 0.5-1.5% of alkyl glycoside, 0.4-1.0% of tween-80, 5-10% of humectant, 0.01-0.1% of sweetening agent, 0.01-0.1% of preservative, 5-10% of ethyl alcohol, and the balance water. The mouthwash stable in system and simple to prepare is capable of cleaning mouth cavities and refreshing breath, is capable of effectively relieving gingivitis and gingival bleeding and can be widely applied.
Description
Technical field
The invention belongs to household chemicals technical field is and in particular to a kind of mouthwash containing sodium copper chlorophyllin.
Background technology
Development with economic society and the continuous improvement of living standard, the oral health consciousness of people greatly enhances, mouth
Chamber care product also gradually develops into multiple care products such as toothpaste, tooth patch, mouthwash by single toothpaste.People consume purpose
Also it is changed into health care and the prevention in oral cavity by single oral cleaning.Mouthwash as a kind of oral health care product, because it is convenient
Property is gradually widely used in people's daily life.
Mouthwash basic function is to clean tooth, fresh breath, reaches the purpose keeping oral cleaning, and with people
The transformation of consumption purpose, proposes more requirements to mouthwash, also add some auxiliary prevention oral cavity diseases in addition to cleaning the teeth
Disease, has the function of nursing role to oral cavity.In recent years, the rise of natural and environmental protection concept, using natural drug, particularly China
Chinese herb medicine is applied in mouthwash the emphasis being Developing and research and development as active component.
Meanwhile, in order that mouthwash has good outward appearance, promote people's consumption it will usually add edible in mouthwash
Pigment, the food coloring commonly used at present is phyllins class, mainly includes chlorophyll paste and sodium copper chlorophyllin.Pasty state
Chlorophyll is chlorophyll magnesium sodium salt, and it is insoluble in water, and stability is also poor, is easily caused product variable color, therefore applies fewer and feweri.
Sodium copper chlorophyllin (CAS：Water solubility 65963-40-8) and stability are all good compared with chlorophyll magnesium sodium salt, its strong coloring force, color
Pool is beautiful, but still poor to light, heat endurance, and its aqueous solution is in emerald green clear liquid, when with the presence of calcium ion or molten
Liquid pH value then has Precipitation when being less than 6, strongly limit the application of sodium copper chlorophyllin；And it is used for because structure limits it
The effect of dyeing is primarily served in oral care implement, and fraction of anti-inflammatory, deodorant, anastalsis.Chinese patent application
CN103751031A discloses a kind of gargle containing antibacterial peptide and sodium copper chlorophyllin, and it includes antibacterial peptide, chlorophyll copper sodium
Salt, menthol, gallic acid, borneol, ethanol and essence.But its well do not solve sodium copper chlorophyllin to light, heat
Instability problem, does not also play the anti-inflammatory of sodium copper chlorophyllin, deodorant, anastalsis well.
Content of the invention
In order to overcome the deficiencies in the prior art, it is an object of the invention to provide a kind of gargling containing sodium copper chlorophyllin
Water, cleanable oral cavity fresh breath, effectively alleviate gingivitis, bleeding gums simultaneously, and improve the steady of sodium copper chlorophyllin
Qualitative.
To achieve these goals, technical scheme is as follows：
A kind of mouthwash containing sodium copper chlorophyllin, is grouped into by the group of following percentage by weight meter：Jasmine is extracted
Thing 1.5～2.5%, Lotus Leafextract 0.5～1.5%, sodium copper chlorophyllin 0.01～0.3%, APG 0.5～1.5%,
Tween-80 0.4～1.0%, NMF 5～10%, sweetener 0.01～0.1%, preservative 0.01～0.1%, ethanol 5～
10%, balance of water.
As the preferred embodiment of the present invention, the described mouthwash containing sodium copper chlorophyllin is by following percentage by weight
The group of meter is grouped into：Jasmine flower extract 2.0%, Lotus Leafextract 1.0%, sodium copper chlorophyllin 0.1%, APG
1.0%th, Tween-80 0.8%, NMF 8%, sweetener 0.06%, preservative 0.05%, ethanol 6%, balance of water.
Further, the preparation method of described jasmine flower extract is as follows：Take Jasmine, add its weight 3～5 times amount
Water, heating and refluxing extraction 2～3h, filters, filtrate relative density at vacuum-concentrcted is to 60 DEG C is 1.10～1.20 leaching
Cream, the vacuum dried prepared jasmine flower extract of medicinal extract.
Further, the preparation method of described Lotus Leafextract is as follows：Take lotus leaf, add the water of its weight 3～5 times amount,
Heating and refluxing extraction 2～3h, filters, filtrate relative density at vacuum-concentrcted is to 60 DEG C is 1.10～1.20 medicinal extract,
The vacuum dried prepared Lotus Leafextract of medicinal extract.
Further, described NMF is at least one in glycerine, sorbierite and propane diols.
Further, described sweetener is at least one in xylitol, D-sorbite and Aspartame.
Further, described preservative is epsilon-polylysine.
Accordingly, the preparation method of the above-mentioned mouthwash containing sodium copper chlorophyllin specifically includes following steps：
S1, take Jasmine, add the water of its weight 3～5 times amount, heating and refluxing extraction 2～3h, filter, filtrate is in vacuum
It is evaporated to the medicinal extract that relative density at 60 DEG C is 1.10～1.20, the vacuum dried prepared jasmine flower extract of medicinal extract, standby
With；
S2, take lotus leaf, add the water of its weight 3～5 times amount, heating and refluxing extraction 2～3h, filter, filtrate subtracts in vacuum
Press and be concentrated into the medicinal extract that relative density at 60 DEG C is 1.10～1.20, the vacuum dried prepared Lotus Leafextract of medicinal extract, standby；
S3, the jasmine flower extract taking formula ratio, Lotus Leafextract, sodium copper chlorophyllin, APG, Tween-80, guarantor
Humectant, sweetener, preservative, the mixing of second alcohol and water, stir, mouthwash containing sodium copper chlorophyllin are obtained.
In technical solution of the present invention, described jasmine flower extract is spent by being dried of Oleaceae gelsemium shrub plant jasmine
It is obtained through water extraction, Lotus Leafextract is obtained through water extraction by the dried leaf of nymphaeaceae plant lotus.
Sodium copper chlorophyllin has certain anti-inflammatory, deodorant, anastalsis, but the consumption in mouthwash is low due to it,
So action effect is inconspicuous.Jasmine and lotus leaf have functions that certain anti-inflammation, clearing heat and detoxicating, and all carry order
The delicate fragrance of people's pleasure, inventor is tentatively used Jasmine and lotus leaf to compound as raw material and sodium copper chlorophyllin to gargle to improve
The anti-inflammatory of saliva, deodorant and anastalsis, for stablizing of guarantee system, the present invention use the water extract of Jasmine and lotus leaf with
Sodium copper chlorophyllin is compounded, studied and tested by continuous, present invention determine that jasmine flower extract, Lotus Leafextract
With the consumption proportion of sodium copper chlorophyllin, under this proportioning, mouthwash of the present invention has substantially to gingivitis, bleeding gums and halitosis
Mitigation, and surprisingly jasmine flower extract, the combination of Lotus Leafextract can significantly improve chlorophyll to allow people
The stability of copper sodium so that mouthwash of the present invention remain in that after placing 18 months under the conditions of room temperature, natural lighting beautiful
Emerald green clear state.
Therefore, compared with prior art, advantage of the invention is that：
(1) present invention contains the mouthwash of sodium copper chlorophyllin with jasmine flower extract, Lotus Leafextract and copper chlorophyll
Sodium salt compounds as active component, cleanable oral cavity fresh breath, effectively alleviates the oral cavities such as gingivitis, bleeding gums simultaneously and asks
Topic.
(2) mouthwash that the present invention contains sodium copper chlorophyllin is in beautiful emerald green, and system clear, steady
Fixed, safety, with Jasmine delicate fragrance, need not additionally add essence；The preparation method of mouthwash of the present invention is simple simultaneously, and condition can
Control, process stabilizing, can industrialized production, be conducive to popularization and application.
Specific embodiment
Further describe the present invention below by way of specific embodiment, but the present invention is not limited only to following examples.?
In the scope of the present invention or without departing from present disclosure, spirit and scope, to Golden flower moisturizing of the present invention essence
Magnificent liquid carries out being suitably modified, replaces effect identical component, it will become apparent to those skilled in the art that they are all
It is deemed to be included within the scope of the present invention.
Embodiment 1, the present invention contain the mouthwash of sodium copper chlorophyllin
Formula：Jasmine flower extract 1.5kg, Lotus Leafextract 0.5kg, sodium copper chlorophyllin 0.01kg, APG
0.5kg, Tween-80 0.4kg, glycerine 5kg, xylitol 0.01kg, epsilon-polylysine 0.01kg, ethanol 5kg, deionized water is mended
Sufficient 100kg.
Preparation method：
S1, take Jasmine, add the water of its weight 3 times amount, heating and refluxing extraction 2h, filter, filtrate is dense in vacuum decompression
It is reduced to the medicinal extract that relative density at 60 DEG C is 1.10, the vacuum dried prepared jasmine flower extract of medicinal extract, standby；
S2, take lotus leaf, add the water of its weight 3 times amount, heating and refluxing extraction 2h, filter, filtrate is in vacuum-concentrcted
To at 60 DEG C, relative density is 1.10 medicinal extract, the vacuum dried prepared Lotus Leafextract of medicinal extract, standby；
S3, the jasmine flower extract taking formula ratio, Lotus Leafextract, sodium copper chlorophyllin, APG, Tween-80, sweet
Oil, xylitol, epsilon-polylysine, the mixing of second alcohol and water, stir, mouthwash containing sodium copper chlorophyllin are obtained.
Embodiment 2, the present invention contain the mouthwash of sodium copper chlorophyllin
Formula：Jasmine flower extract 2.5kg, Lotus Leafextract 1.5kg, sodium copper chlorophyllin 0.3kg, APG
1.5kg, Tween-80 1.0kg, sorbierite 10kg, D-sorbite 0.1kg, epsilon-polylysine 0.1kg, ethanol 10kg, deionization
Water supplies 100kg.
Preparation method：
S1, take Jasmine, add the water of its weight 5 times amount, heating and refluxing extraction 3h, filter, filtrate is dense in vacuum decompression
It is reduced to the medicinal extract that relative density at 60 DEG C is 1.20, the vacuum dried prepared jasmine flower extract of medicinal extract, standby；
S2, take lotus leaf, add the water of its weight 5 times amount, heating and refluxing extraction 3h, filter, filtrate is in vacuum-concentrcted
To at 60 DEG C, relative density is 1.20 medicinal extract, the vacuum dried prepared Lotus Leafextract of medicinal extract, standby；
S3, the jasmine flower extract taking formula ratio, Lotus Leafextract, sodium copper chlorophyllin, APG, Tween-80, mountain
Pears alcohol, D-sorbite, epsilon-polylysine, the mixing of second alcohol and water, stir, mouthwash containing sodium copper chlorophyllin are obtained.
Embodiment 3, the present invention contain the mouthwash of sodium copper chlorophyllin
Formula：Jasmine flower extract 1.5kg, Lotus Leafextract 1.5kg, sodium copper chlorophyllin 0.2kg, APG
0.5kg, Tween-80 1.0kg, propane diols 6kg, Aspartame 0.1kg, epsilon-polylysine 0.05kg, ethanol 8kg, deionized water
Supply 100kg.
Preparation method：
S1, take Jasmine, add the water of its weight 3 times amount, heating and refluxing extraction 3h, filter, filtrate is dense in vacuum decompression
It is reduced to the medicinal extract that relative density at 60 DEG C is 1.10, the vacuum dried prepared jasmine flower extract of medicinal extract, standby；
S2, take lotus leaf, add the water of its weight 5 times amount, heating and refluxing extraction 2h, filter, filtrate is in vacuum-concentrcted
To at 60 DEG C, relative density is 1.20 medicinal extract, the vacuum dried prepared Lotus Leafextract of medicinal extract, standby；
S3, the jasmine flower extract taking formula ratio, Lotus Leafextract, sodium copper chlorophyllin, APG, Tween-80, third
Glycol, Aspartame, epsilon-polylysine, the mixing of second alcohol and water, stir, mouthwash containing sodium copper chlorophyllin are obtained.
Embodiment 4, the present invention contain the mouthwash of sodium copper chlorophyllin
Formula：Jasmine flower extract 2.0kg, Lotus Leafextract 1.0kg, sodium copper chlorophyllin 0.1kg, APG
1.0kg, Tween-80 0.8kg, sorbierite 8kg, xylitol 0.06kg, epsilon-polylysine 0.05kg, ethanol 6kg, deionized water
Supply 100kg.
Preparation method：
S1, take Jasmine, add the water of its weight 4 times amount, heating and refluxing extraction 2h, filter, filtrate is dense in vacuum decompression
It is reduced to the medicinal extract that relative density at 60 DEG C is 1.20, the vacuum dried prepared jasmine flower extract of medicinal extract, standby；
S2, take lotus leaf, add the water of its weight 4 times amount, heating and refluxing extraction 2h, filter, filtrate is in vacuum-concentrcted
To at 60 DEG C, relative density is 1.20 medicinal extract, the vacuum dried prepared Lotus Leafextract of medicinal extract, standby；
S3, the jasmine flower extract taking formula ratio, Lotus Leafextract, sodium copper chlorophyllin, APG, Tween-80, mountain
Pears alcohol, xylitol, epsilon-polylysine, the mixing of second alcohol and water, stir, mouthwash containing sodium copper chlorophyllin are obtained.
Comparative example 1,
Formula：Jasmine flower extract 3.0kg, sodium copper chlorophyllin 0.15kg, APG 1.0kg, Tween-80
0.8kg, sorbierite 8kg, xylitol 0.06kg, epsilon-polylysine 0.05kg, ethanol 6kg, deionized water supplies 100kg.Preparation
Method reference implementation example 4.
Compared with Example 4, this comparative example does not contain Lotus Leafextract, and improves jasmine flower extract and copper chlorophyll
Sodium salt consumption, but both constant rates.
Comparative example 2,
Formula：Lotus Leafextract 3.0kg, sodium copper chlorophyllin 0.3kg, APG 1.0kg, Tween-80 0.8kg, mountain
Pears alcohol 8kg, xylitol 0.06kg, epsilon-polylysine 0.05kg, ethanol 6kg, deionized water supplies 100kg.Preparation method reference
Embodiment 4.
Compared with Example 4, this comparative example does not contain jasmine flower extract, and improves Lotus Leafextract and copper chlorophyll
Sodium salt consumption, but both constant rates.
Comparative example 3,
Formula：Jasmine flower extract 2.0kg, Lotus Leafextract 1.0kg, APG 1.0kg, Tween-80 0.8kg, mountain
Pears alcohol 8kg, xylitol 0.06kg, epsilon-polylysine 0.05kg, ethanol 6kg, deionized water supplies 100kg.Preparation method reference
Embodiment 4.
Compared with Example 4, this comparative example does not contain sodium copper chlorophyllin.
Comparative example 4,
Formula：Sodium copper chlorophyllin 0.1kg, APG 1.0kg, Tween-80 0.8kg, sorbierite 8kg, xylitol
0.06kg, epsilon-polylysine 0.05kg, ethanol 6kg, deionized water supplies 100kg.Preparation method reference implementation example 4.
Compared with Example 4, this comparative example does not contain jasmine flower extract and Lotus Leafextract.
Test example one, the present invention contain the irritation test of the mouthwash of sodium copper chlorophyllin
Eye irritation is checked：Select healthy adult white rabbit 3 (eyes check), gently pull open rabbit one branch hole
The palpebra inferior of eyeball, by tested material 0.1mL, (2) instill in conjunctival sac, make upper and lower eyelid passively close 1s, to prevent tested material
Lose.Opposite side eyes are not processed as own control.Observed with magnifying glass after 1h, result see table 1.
Table 1 mouthwash excitant contrast experiment
From upper table 1, the present invention contains the mouthwash nonirritant of sodium copper chlorophyllin.
Test example two, the present invention contain the application effect of the mouthwash of sodium copper chlorophyllin
(1) remission effect to gingivitis, bleeding gums
Invite and suffer from gingivitis, volunteer 96 people of bleeding gums, be randomly divided into 8 groups, every group of 12 people, try out respectively and implement
The mouthwash that example 1～4, comparative example 1～4 are obtained, respectively uses 1 time sooner or later, and each 20ml contains 30s～60s.Result see table 2.
Table 2 uses gingivitis, bleeding gums evaluation result before and after mouthwash
Note：BOP% is the percentage that the site having bleeding after spy is examined accounts for the total site of full mouth.
From upper table 2：The gingivitis bleeding containing the mouthwash of sodium copper chlorophyllin for the embodiment of the present invention 1～4 refers to
Mark BOP% has clear improvement, and shows that mouthwash of the present invention has functions that more apparent to improve gingivitis, bleeding gums；Wherein implement
The BOP% target improvement of example 4 is the most obvious, is highly preferred embodiment of the present invention.Comparative example 1 does not contain Lotus Leafextract, and comparative example 2 is not
Containing jasmine flower extract, comparative example 3 does not contain sodium copper chlorophyllin, and comparative example 4 only contains sodium copper chlorophyllin, and its mouthwash is to gum
Inflammation bleeding index BOP% is not improved effect.
(2) remove halitosis effect
Not yet there is deodorant standard in China, borrows the standard of the direct sense of smell method of European Union SCCNFP, halitosis is divided Pyatyi.One
Level, no halitosis；Two grades of very slight halitosis；The slight halitosis of three-level；Level Four moderate halitosis；The strong halitosis of Pyatyi.
Invite 80 volunteers, be randomly divided into 8 groups, the mouthwash that embodiment 1～4 on probation, comparative example 1～4 are obtained respectively.
Test front 8 groups of volunteers to drink into 150ml beer, a garlic fried shredded pork and two small steamed buns.Gargled with cold boiling water after the meal, by commenting
Fragrant teacher detects oral peculiar smell, as benchmark.After 1 hour, with above-mentioned mouthwash 30 seconds, rest 30 minutes.Again by commenting fragrant teacher
Evaluation halitosis level, using result as the evaluation result except halitosis, result see table 3.
The each mouthwash deodorizing effect of table 3 is evaluated
The computational methods of halitosis integration：Σ stink rank × number of cases.
From upper table 3, halitosis integration is higher after the meal, and each group halitosis integrates indifference；Using the embodiment of the present invention 1～
After 4 mouthwashes, halitosis integration has obvious reduction, shows that mouthwash of the present invention effectively removes halitosis, wherein embodiment 4 except halitosis effect
Fruit is the most obvious, is highly preferred embodiment of the present invention.And comparative example 1～4 except halitosis DeGrain.
Test example three, the present invention contain the stability of the mouthwash of sodium copper chlorophyllin
1st, test material：The mouthwash that embodiment 1～4, comparative example 1～4 are obtained.
2nd, test method：Above-mentioned mouthwash is carried out with long term test, observes outward appearance and the color and luster of mouthwash.
3rd, result of the test：Result of the test is as shown in table 4 below.
The long-term test results of each mouthwash of table 4
As shown in Table 4：The mouthwash containing sodium copper chlorophyllin for the embodiment of the present invention 1～4 is in room temperature, natural lighting condition
Lower place 18 months after remain in that clear and beautiful emerald green, and comparative example 1～4 mouthwash began to after 3 months
Different degrees of muddiness or precipitation, oxidative phenomena occur, reflects mouthwash of the present invention and there is higher stability, can be effective
Holding mouthwash organoleptic indicator, extend product shelf-life.
Above-described embodiment only principle of the illustrative present invention and its effect, not for the restriction present invention.Any ripe
The personage knowing this technology all can carry out modifications and changes without prejudice under the spirit and the scope of the present invention to above-described embodiment.Cause
This, those of ordinary skill in the art is complete with institute under technological thought without departing from disclosed spirit such as
All equivalent modifications becoming or change, must be covered by the claim of the present invention.
Claims (8)
1. a kind of mouthwash containing sodium copper chlorophyllin is it is characterised in that be grouped into by the group of following percentage by weight meter：Jasmine
Jasmine flower extract 1.5～2.5%, Lotus Leafextract 0.5～1.5%, sodium copper chlorophyllin 0.01～0.3%, APG 0.5
～1.5%, Tween-80 0.4～1.0%, NMF 5～10%, sweetener 0.01～0.1%, preservative 0.01～0.1%,
Ethanol 5～10%, balance of water.
2. as claimed in claim 1 the mouthwash containing sodium copper chlorophyllin it is characterised in that by following percentage by weight meter
Group is grouped into：Jasmine flower extract 2.0%, Lotus Leafextract 1.0%, sodium copper chlorophyllin 0.1%, APG 1.0%, tell
Temperature -800.8%, NMF 8%, sweetener 0.06%, preservative 0.05%, ethanol 6%, balance of water.
3. as claimed in claim 1 or 2 the mouthwash containing sodium copper chlorophyllin it is characterised in that described jasmine flower extract
Preparation method as follows：Take Jasmine, add the water of its weight 3～5 times amount, heating and refluxing extraction 2～3h, filter, filtrate exists
Vacuum-concentrcted relative density at 60 DEG C is 1.10～1.20 medicinal extract, and medicinal extract extracts by vacuum dried prepared Jasmine
Thing.
4. as claimed in claim 1 or 2 the mouthwash containing sodium copper chlorophyllin it is characterised in that described Lotus Leafextract
Preparation method is as follows：Take lotus leaf, add the water of its weight 3～5 times amount, heating and refluxing extraction 2～3h, filter, filtrate is in vacuum
It is evaporated to the medicinal extract that relative density at 60 DEG C is 1.10～1.20, the vacuum dried prepared Lotus Leafextract of medicinal extract.
5. as claimed in claim 1 or 2 the mouthwash containing sodium copper chlorophyllin it is characterised in that described NMF be glycerine,
At least one in sorbierite and propane diols.
6. the mouthwash containing sodium copper chlorophyllin as claimed in claim 1 or 2 is it is characterised in that described sweetener is wood sugar
At least one in alcohol, D-sorbite and Aspartame.
7. as claimed in claim 1 or 2 the mouthwash containing sodium copper chlorophyllin it is characterised in that described preservative is ε-poly-
Lysine.
8. as claimed in claim 1 or 2 the mouthwash containing sodium copper chlorophyllin preparation method it is characterised in that include with
Lower step：
S1, take Jasmine, add the water of its weight 3～5 times amount, heating and refluxing extraction 2～3h, filter, filtrate is in vacuum decompression
It is concentrated into the medicinal extract that relative density at 60 DEG C is 1.10～1.20, the vacuum dried prepared jasmine flower extract of medicinal extract, standby；
S2, take lotus leaf, add the water of its weight 3～5 times amount, heating and refluxing extraction 2～3h, filter, filtrate is dense in vacuum decompression
It is reduced to the medicinal extract that relative density at 60 DEG C is 1.10～1.20, the vacuum dried prepared Lotus Leafextract of medicinal extract, standby；
S3, take formula ratio jasmine flower extract, Lotus Leafextract, sodium copper chlorophyllin, APG, Tween-80, NMF,
Sweetener, preservative, the mixing of second alcohol and water, stir, mouthwash containing sodium copper chlorophyllin are obtained.
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| CN201610928857.9A CN106389205B (en) | 2016-10-31 | 2016-10-31 | A kind of mouthwash containing sodium copper chlorophyllin |
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| CN201610928857.9A CN106389205B (en) | 2016-10-31 | 2016-10-31 | A kind of mouthwash containing sodium copper chlorophyllin |
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| CN106389205B CN106389205B (en) | 2017-07-25 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107149571A (en) * | 2017-04-17 | 2017-09-12 | 廖华勇 | Jasmin general type mouthwash |
| CN107308058A (en) * | 2017-07-28 | 2017-11-03 | 张可池 | A kind of mouthwash containing sterculia nobilis's berry extract |
| CN112754980A (en) * | 2021-02-26 | 2021-05-07 | 西南医科大学附属中医医院 | Toothpaste with antibacterial effect and preparation method thereof |
| CN116211768A (en) * | 2023-03-17 | 2023-06-06 | 合肥贝壳派创新科技有限公司 | Tremella polysaccharide tooth cleaning care solution and preparation process thereof |
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| CN107149571A (en) * | 2017-04-17 | 2017-09-12 | 廖华勇 | Jasmin general type mouthwash |
| CN107308058A (en) * | 2017-07-28 | 2017-11-03 | 张可池 | A kind of mouthwash containing sterculia nobilis's berry extract |
| CN112754980A (en) * | 2021-02-26 | 2021-05-07 | 西南医科大学附属中医医院 | Toothpaste with antibacterial effect and preparation method thereof |
| CN116211768A (en) * | 2023-03-17 | 2023-06-06 | 合肥贝壳派创新科技有限公司 | Tremella polysaccharide tooth cleaning care solution and preparation process thereof |
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