CN106333891A - Anti-inflammation and pain-alleviating toothpaste and preparation method thereof - Google Patents
Anti-inflammation and pain-alleviating toothpaste and preparation method thereof Download PDFInfo
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- CN106333891A CN106333891A CN201610858584.5A CN201610858584A CN106333891A CN 106333891 A CN106333891 A CN 106333891A CN 201610858584 A CN201610858584 A CN 201610858584A CN 106333891 A CN106333891 A CN 106333891A
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- toothpaste
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- inflammatory analgetic
- pomelo peel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
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Abstract
The invention discloses an anti-inflammation and pain-alleviating toothpaste and a preparation method of the anti-inflammation and pain-alleviating toothpaste and belongs to the technical field of daily chemical product processing. The anti-inflammation and pain-alleviating toothpaste comprises the following ingredients in parts by weight: 10-20 parts of a friction agent, 30-50 parts of a humectant, 10-20 parts of a shaddock peel extract, 10-20 parts of a Chinese herbal medicine additive, 1-5 parts of a surfactant, 1-2 parts of a thickening agent, 1-2 parts of a sweetening agent and 1-2 parts of a preservative. Active ingredients are extracted from shaddock peel; the prepared extract is added to the toothpaste; the cleaning ability of the toothpaste is improved; ophioglossum vulgatum in the Chinese herbal medicine additive has the effects of clearing away heat and toxic materials, diminishing swelling and alleviating pain and can treat oral diseases; solani nigri herba has the effects of inhibiting bacteria, promoting blood circulation and diminishing the swelling; and the shaddock peel extract, the Chinese herbal medicine additive and mint are added to the toothpaste at the same time, so that the prepared toothpaste has the strong cleaning ability and the effects of diminishing inflammation, alleviating pain, protecting gingivae and refreshing breath.
Description
[technical field]
The present invention relates to chemical product processing technique field is and in particular to a kind of anti-inflammatory analgetic toothpaste and preparation method thereof.
[background technology]
Tooth is mainly used in laboratory rodent chow and helps pronunciation, and the integrality of tooth also has very big shadow to the looks of people simultaneously
Ring, because the support of tooth and alveolar bone, Arch width and occluding relation is normal, just the face that can make one and lip and cheek seem
Plentiful.When people are in speech and smile, neat and pure white tooth, just can manifest health and the beauty of people.On the contrary, if tooth
Bow growth is abnormal, and teeth arrangement disorder is uneven, and face will seem inharmonious；If absence of tooth is too many, lip and cheek
Lose support and be recessed, the face that will make one presents a weathered appearance and becomes thin.Therefore protect the shape of tooth and integrality seems outstanding
It is important.
Because people needs by oral cavity dietary intake daily, easily breed bacteria in oral cavity, causes various oral problem, mouth
Being attached in dental surface and teeth space mainly due to swill of chamber problem, leads to the amount reproduction of bacterium, simultaneously bacterium
Corrosion tooth, the secretion of generation forms hard tartar, is difficult to remove, and the gas that the food of bacterium decomposition simultaneously produces causes mouth
Smelly, the breeding of bacterium or edible irritable food etc. all can cause swelling and aching of gum, bleeding and oral lesions etc., have a strong impact on people's
Oral health and personal image, the therefore cleaning to tooth and oral cavity, improve oral environment and are very important.
Toothpaste is the cleaning agent of people's daily cleaning tooth, can be attached to the tartar on tooth with effective cleaning, have strong
Tooth protects effect that gum keeps oral cleaning, for various oral problem, prepares the toothpaste of difference in functionality, often adds in toothpaste
Various compositions obtain the toothpaste with difference in functionality, are required with the routine use meeting people.Chinese herbal medicine is widely present in nature
In boundary, raw material is easy to get and harmless, adds the medicinal herb componentses with difference in functionality in toothpaste, can be with effectively treatment mouth
Chamber health problem, and can be utilized the natural faint scent of plant to improve oral environment.
Pomelo peel contains the compound of parents' molecular chaperones, and it is similar with the composition of the surfactant in washing agent, tool
Have the ability that good decontamination is deoiled, by soak, these compositions can be allowed fully to be separated out, pomelo peel also contain naringin,
Essential oil, pigment etc., it is fungi-proofing to have an anti-inflammatory, has protective effect to skin.
[content of the invention]
It is an object of the invention to: for above-mentioned problem, provide a kind of anti-inflammatory analgetic toothpaste and preparation method thereof,
By adding pomelo peel extract and the medicinal herb componentses with anti-inflammatory analgetic, the toothpaste cleaning dirt-removing power of preparation in toothpaste
By force, there is the effect of anti-inflammatory analgetic simultaneously, using rear breath freshening.
To achieve these goals, the technical solution used in the present invention is as follows: a kind of anti-inflammatory analgetic toothpaste, including weighing as follows
The component of amount number: rubbing agent 10-20 part, NMF 30-50 part, pomelo peel extract 10-20 part, Chinese herb feed additive 10-
20 parts, surfactant 1-5 part, thickener 1-2 part, sweetener 1-2 part and preservative 1-2 part.
Described Chinese herb feed additive is made up of the raw material of following weight portion: one leaf grass 50-100 part, black nightshade grass 50-100 part,
Peppermint 50-100 part and water 100-200 part.
Described pomelo peel extract is to be immersed in after blending in the water of 1-1.5 times of weight by shaddock green-skinned, through anti-
The liquid that after multiple freeze-thaw process, squeeze and filter obtains.
Described rubbing agent includes egg-shell meal, oyster shell whiting, calcium carbonate, calcium monohydrogen phosphate, calcium pyrophosphate, silica and hydroxide
One of aluminium or two or more compositions.
Described NMF includes one of glycerine, sorbierite, xylitol, polyethylene glycol and water or two or more combinations
Thing.
Described surfactant is sodium lauryl sulfate or 2- acyloxy key sodium sulfonate.
Described thickener includes carboxymethylcellulose calcium, deer horn pectin, hydroxyethyl cellulose, xanthans, guar gum and angle fork
One of glue or two or more compositions.
Described sweetener is cyclohexylamine sulfonic acid sodium and/or saccharin sodium.
Described preservative is sorbic acid sylvite and/or Sodium Benzoate.
Present invention also offers a kind of preparation method of described anti-inflammatory analgetic toothpaste, comprise the steps:
(1) pomelo peel is removed white portion and take shaddock green-skinned；It is immersed in 1-1.5 after shaddock green-skinned is blended
In the water of times weight, under conditions of -50 DEG C to -20 DEG C, freeze 40-60 minute, take out defrosting 15- in 40-60 DEG C of water-bath
30 minutes, after freeze-thaw processes 3-4 time repeatedly, squeezing, filtration obtained final product pomelo peel extract；
(2) 50-100 part one leaf grass, 50-100 part black nightshade grass and 50-100 part peppermint are put in 100-200 part water, lead to
Cross pulper to smash, filter taking juice, as Chinese herb feed additive；
(3) by 30-50 part NMF, 10-20 part pomelo peel extract, 10-20 part Chinese herb feed additive, 1-5 part surface
Activating agent, 1-2 part thickener, 1-2 part sweetener and 1-2 part preservative put in reactor mix and blend 0.5-1 at room temperature
Hour, add stirring 1-2 hour under 10-20 part rubbing agent room temperature, transfer to grinding machine for grinding 1-2 hour, obtain sticky
The toothpaste of fine and smooth lotion, the as present invention.
In sum, due to employing technique scheme, the invention has the beneficial effects as follows: the present invention passes through repeatedly repeatedly
Freezing, defrosting and expressing process extract to the active ingredient in pomelo peel, so that the cell membrane in pomelo peel is destroyed, its
Active ingredient fully leaches, and improves the recovery rate of pomelo peel extract.The pomelo peel extracting extract is added to simultaneously
In toothpaste, improve the cleaning capacity of toothpaste；Pomelo peel extract also have anti-inflammatory fungi-proofing, protection skin effect；Chinese herbal medicine
A leaf grass in additive has clearing heat and detoxicating and swelling and pain relieving effect, can treat oral disease, black nightshade grass have antibacterial and
Activating blood circulation and reducing swelling acts on；Pomelo peel extract, Chinese herb feed additive and peppermint are added the work producing Synergistic in toothpaste simultaneously
With the toothpaste cleaning capacity of preparation is strong, and has anti-inflammatory analgetic, protection gum and fresh breath effect.
[specific embodiment]
With reference to specific embodiment, technical scheme is made with the explanation carrying out further.
Comparative example 1
(1) 50 part of one leaf grass, 50 parts of black nightshade grass and 50 portions of peppermints are put into 100 parts of water and smashed in pulper, filter to take
Juice, as Chinese herb feed additive；
(2) by 50 parts of glycerine, 20 parts of Chinese herb feed additives, 5 parts of sodium lauryl sulfates, 2 parts of carboxymethylcellulose calciums, 1 part of ring
Hexylamine sodium sulfonate and 2 parts of sorbic acid sylvite put in reactors mix and blend 1 hour at room temperature, add 10 parts of egg shell powders and
Stir 2 hours under 10 parts of calcium carbonate room temperatures, transfer to grinding machine for grinding 2 hours, obtain sticky exquisiteness lotion, the as present invention
The toothpaste of embodiment.
Embodiment 1
(1) pomelo peel is removed white portion and take shaddock green-skinned；It is immersed in 1 times of weight after shaddock green-skinned is blended
In the water of amount, freezing under the conditions of -50 DEG C was taken out after 40 minutes, thawed 15 minutes in 60 DEG C of water-bath, freeze-thaw repeatedly
After processing 3 times, squeezing, filtration obtain final product pomelo peel extract；
(2) 50 part of one leaf grass, 50 parts of black nightshade grass and 50 portions of peppermints are put into 100 parts of water and smashed in pulper, filter to take
Juice, as Chinese herb feed additive；
(3) by 30 parts of glycerine, 20 parts of pomelo peel extracts, 20 parts of Chinese herb feed additives, 5 parts of sodium lauryl sulfates, 2 parts of carboxylics
Methylcellulose, 1 part of cyclohexylamine sulfonic acid sodium and 2 parts of sorbic acid sylvite put in reactors mix and blend 1 hour at room temperature, plus
Enter and stir 2 hours under 10 parts of egg shell powders and 10 parts of calcium carbonate room temperatures, transfer to grinding machine for grinding 2 hours, obtain sticky thin
The toothpaste of greasy lotion, the as embodiment of the present invention.
In the embodiment of the present invention, also choosing 50 respectively has swelling and aching of gum and the patient of tartar to use the embodiment of the present invention
With the toothpaste of comparative example, as shown in table 1 using statistics after 5 days.
Table 1: choose 50 patients having swelling and aching of gum and tartar respectively and use the embodiment of the present invention and comparative example toothpaste
Effect
By contrasting the embodiment of the present invention and comparative example using effect, the embodiment of the present invention after addition pomelo peel extract
Cleaning effect is substantially better than the comparative example without pomelo peel extract, and has synergy to swelling and aching of gum effect.
Comparative example 2
(1) pomelo peel is removed white portion and take shaddock green-skinned；Shaddock green-skinned is blended and is immersed in 1.5 times of weights
In the water of amount, freeze 60 minutes under the conditions of -20 DEG C, take out and thaw 30 minutes in 40 DEG C of water-bath, repeatedly at freeze-thaw
After reason 4 times, squeezing, filtration obtain final product pomelo peel extract；
(2) 100 part of one leaf grass and 100 portions of peppermints are put into 130 parts of water and smashed in pulper, filter taking juice, as
Chinese herb feed additive；
(3) by 50 parts of polyethylene glycol, 15 parts of pomelo peel extracts, 15 parts of Chinese herb feed additives, 1 part of 2- acyloxy key sulfonic acid
Sodium, 1 part of hydroxyethyl cellulose, 2 parts of saccharin sodiums and 1 part of Sodium Benzoate put in reactor mix and blend 1 hour at room temperature, plus
Enter and stir 1.5 hours under 15 parts of oyster shell whiting room temperatures, transfer to grinding machine for grinding 1.5 hours, obtain sticky exquisiteness lotion, as
The toothpaste of the embodiment of the present invention.
Embodiment 2
(1) pomelo peel is removed white portion and take shaddock green-skinned；Shaddock green-skinned is blended and is immersed in 1.5 times of weights
In the water of amount, freeze 60 minutes under the conditions of -20 DEG C, take out and thaw 30 minutes in 40 DEG C of water-bath, repeatedly at freeze-thaw
After reason 4 times, squeezing, filtration obtain final product pomelo peel extract；
(2) 100 part of one leaf grass, 100 parts of black nightshade grass and 100 portions of peppermints are put into 200 parts of water and smashed in pulper, filter
Taking juice, as Chinese herb feed additive；
(3) by 50 parts of polyethylene glycol, 15 parts of pomelo peel extracts, 15 parts of Chinese herb feed additives, 1 part of 2- acyloxy key sulfonic acid
Sodium, 1 part of hydroxyethyl cellulose, 2 parts of saccharin sodiums and 1 part of Sodium Benzoate put in reactor mix and blend 1 hour at room temperature, plus
Enter and stir 1.5 hours under 15 parts of oyster shell whiting room temperatures, transfer to grinding machine for grinding 1.5 hours, obtain sticky exquisiteness lotion, as
The toothpaste of the embodiment of the present invention.
In the embodiment of the present invention, also choosing 50 respectively has swelling and aching of gum and the patient of tartar to use the embodiment of the present invention
With the toothpaste of comparative example, as shown in table 2 using statistics after 5 days.
Table 2: choose 50 patients having swelling and aching of gum and tartar respectively and use the embodiment of the present invention and comparative example toothpaste
Effect
By contrasting the embodiment of the present invention and comparative example using effect, after adding black nightshade grass, the embodiment of the present invention is to improving tooth
The effect that gum swells and ache is substantially better than the comparative example without black nightshade grass, and has synergy to cleaning effect.
Comparative example 3
(1) pomelo peel is removed white portion and take shaddock green-skinned；Shaddock green-skinned is blended and is immersed in 1.2 times of weights
In the water of amount, freeze 50 minutes under the conditions of -40 DEG C, take out and thaw 20 minutes in 50 DEG C of water-bath, repeatedly at freeze-thaw
After reason 4 times, squeezing, filtration obtain final product pomelo peel extract；
(2) 80 part of one leaf grass and 80 portions of peppermints are put into 100 parts of water and are smashed in pulper, filter taking juice, as in
Chinese herbal medicine additive agent；
(3) by 40 parts of xylitols, 18 parts of pomelo peel extracts, 18 parts of Chinese herb feed additives, 4 parts of 2- acyloxy key sulfonic acid
Sodium, 2 parts of deer horn pectin, 1 part of saccharin sodium and 2 parts of Sodium Benzoates put in reactors mix and blend 1 hour at room temperature, add 15
Stir 1 hour under part aluminium hydroxide room temperature, transfer to grinding machine for grinding 1 hour, obtain sticky exquisiteness lotion, the as present invention
The toothpaste of embodiment.
Embodiment 3
(1) pomelo peel is removed white portion and take shaddock green-skinned；Shaddock green-skinned is blended and is immersed in 1.2 times of weights
In the water of amount, freeze 50 minutes under the conditions of -40 DEG C, take out and thaw 20 minutes in 50 DEG C of water-bath, repeatedly at freeze-thaw
After reason 4 times, squeezing, filtration obtain final product pomelo peel extract；
(2) 80 part of one leaf grass, 80 parts of black nightshade grass and 80 portions of peppermints are put into 150 parts of water and smashed in pulper, filter to take
Juice, as Chinese herb feed additive；
(3) by 40 parts of xylitols, 18 parts of pomelo peel extracts, 18 parts of Chinese herb feed additives, 4 parts of 2- acyloxy key sulfonic acid
Sodium, 2 parts of deer horn pectin, 1 part of saccharin sodium and 2 parts of Sodium Benzoates put in reactors mix and blend 1 hour at room temperature, add 15
Stir 1 hour under part aluminium hydroxide room temperature, transfer to grinding machine for grinding 1 hour, obtain sticky exquisiteness lotion, the as present invention
The toothpaste of embodiment.
In the embodiment of the present invention, also choosing 50 respectively has swelling and aching of gum and the patient of tartar to use the embodiment of the present invention
With the toothpaste of comparative example of the present invention, as shown in table 3 using statistics after 5 days.
Table 3: choose 50 patients having swelling and aching of gum and tartar respectively and use the embodiment of the present invention and comparative example toothpaste
Effect
By contrasting the embodiment of the present invention and comparative example using effect, after adding a leaf grass, the embodiment of the present invention is to improving tooth
The effect that gum swells and ache is substantially better than the comparative example without a leaf grass, and has synergy to cleaning effect.
Result is used from the comparative example of various embodiments of the present invention, in the situation less than a week using toothpaste of the present invention
Under, the swelling and aching of gum of patient and tartar are obviously improved, and illustrate that the toothpaste cleaning effect of the present invention is good, and swelling and aching of gum problem is improved
Effect is obvious.
Described above is the detailed description for the preferable possible embodiments of the present invention, but embodiment is not limited to this
Bright patent claim, the equal change being completed under the technical spirit suggested by all present invention or modification change, all should belong to
In the covered the scope of the claims of the present invention.
Claims (9)
1. a kind of anti-inflammatory analgetic toothpaste is it is characterised in that include the component of following parts by weight: rubbing agent 10-20 part, NMF
30-50 part, pomelo peel extract 10-20 part, Chinese herb feed additive 10-20 part, surfactant 1-5 part, thickener 1-2 part,
Sweetener 1-2 part and preservative 1-2 part；
Described Chinese herb feed additive is made up of the raw material of following weight portion: a leaf grass 50-100 part, black nightshade grass 50-100 part, peppermint
50-100 part and water 100-200 part.
2. anti-inflammatory analgetic toothpaste according to claim 1 is it is characterised in that described pomelo peel extract is by shaddock green
Crust is immersed in the water of 1-1.5 times of weight after blending, the liquid that after processing through freeze-thaw repeatedly, squeezing, filtration obtain.
3. anti-inflammatory analgetic toothpaste according to claim 1 it is characterised in that described rubbing agent include egg-shell meal, oyster shell whiting,
One of calcium carbonate, calcium monohydrogen phosphate, calcium pyrophosphate, silica and aluminium hydroxide or two or more compositions.
4. anti-inflammatory analgetic toothpaste according to claim 1 is it is characterised in that described NMF includes glycerine, sorbierite, wood
One of sugar alcohol, polyethylene glycol and water or two or more compositions.
5. anti-inflammatory analgetic toothpaste according to claim 1 is it is characterised in that described surfactant is sodium lauryl sulfate
Or 2- acyloxy key sodium sulfonate.
6. anti-inflammatory analgetic toothpaste according to claim 1 it is characterised in that described thickener include carboxymethylcellulose calcium,
One of deer horn pectin, hydroxyethyl cellulose, xanthans, guar gum and carrageenan or two or more compositions.
7. anti-inflammatory analgetic toothpaste according to claim 1 it is characterised in that described sweetener be cyclohexylamine sulfonic acid sodium and/
Or saccharin sodium.
8. anti-inflammatory analgetic toothpaste according to claim 1 it is characterised in that described preservative be sorbic acid sylvite and/or
Sodium Benzoate.
9. a kind of preparation method of the anti-inflammatory analgetic toothpaste described in any one of claim 1 to 8 is it is characterised in that include as follows
Step:
(1) pomelo peel is removed white portion and take shaddock green-skinned；It is immersed in 1-1.5 times after shaddock green-skinned is blended to weigh
In the water of amount, under conditions of -50 DEG C to -20 DEG C, freeze 40-60 minute, take out defrosting 15-30 in 40-60 DEG C of water-bath and divide
Clock, after freeze-thaw processes 3-4 time repeatedly, squeezing, filtration obtain final product pomelo peel extract；
(2) 50-100 part one leaf grass, 50-100 part black nightshade grass and 50-100 part peppermint are put in 100-200 part water, by stirring
Broken machine is smashed, and filters taking juice, as Chinese herb feed additive；
(3) by 30-50 part NMF, 10-20 part pomelo peel extract, 10-20 part Chinese herb feed additive, 1-5 part surface-active
Agent, 1-2 part thickener, 1-2 part sweetener and 1-2 part preservative put in reactor mix and blend 0.5-1 hour at room temperature,
Add stirring 1-2 hour under 10-20 part rubbing agent room temperature, transfer to grinding machine for grinding 1-2 hour, obtain sticky exquisiteness cream
The toothpaste of body, the as present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610858584.5A CN106333891A (en) | 2016-09-27 | 2016-09-27 | Anti-inflammation and pain-alleviating toothpaste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610858584.5A CN106333891A (en) | 2016-09-27 | 2016-09-27 | Anti-inflammation and pain-alleviating toothpaste and preparation method thereof |
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| CN106333891A true CN106333891A (en) | 2017-01-18 |
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| CN201610858584.5A Pending CN106333891A (en) | 2016-09-27 | 2016-09-27 | Anti-inflammation and pain-alleviating toothpaste and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107320368A (en) * | 2017-06-23 | 2017-11-07 | 广州暨南生物医药研究开发基地有限公司 | A kind of adult's toothpaste of the ash containing Chinese mugwort and preparation method thereof |
| CN109350581A (en) * | 2017-12-26 | 2019-02-19 | 李文婷 | A kind of oral cavity nursing agent of anti-inflammatory whitening |
-
2016
- 2016-09-27 CN CN201610858584.5A patent/CN106333891A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 中华人民共和国国家质量监督检验检疫总局和中国国家标准化管理委员会: "《牙膏用原料规范》", 1 June 2009 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107320368A (en) * | 2017-06-23 | 2017-11-07 | 广州暨南生物医药研究开发基地有限公司 | A kind of adult's toothpaste of the ash containing Chinese mugwort and preparation method thereof |
| CN109350581A (en) * | 2017-12-26 | 2019-02-19 | 李文婷 | A kind of oral cavity nursing agent of anti-inflammatory whitening |
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Application publication date: 20170118 |