CN106306371A - Nanoscale traditional Chinese medicine feed additive facilitating promotion of oestrus of dams and preparation method of nanoscale traditional Chinese medicine feed additive - Google Patents
Nanoscale traditional Chinese medicine feed additive facilitating promotion of oestrus of dams and preparation method of nanoscale traditional Chinese medicine feed additive Download PDFInfo
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- CN106306371A CN106306371A CN201610080166.8A CN201610080166A CN106306371A CN 106306371 A CN106306371 A CN 106306371A CN 201610080166 A CN201610080166 A CN 201610080166A CN 106306371 A CN106306371 A CN 106306371A
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Abstract
The invention provides a nanoscale traditional Chinese medicine feed additive facilitating promotion of oestrus of dams and a preparation method of the nanoscale traditional Chinese medicine feed additive. The nanoscale traditional Chinese medicine feed additive is prepared from the following components in percentage by weight: 15-25% of Chinese mugwort stored for one year or long, 20-50% of leonurus artemisia, 3-5% of radix angelica sinensis, 20%-33% of calcium chloride, 15%-28% of glucose, 22%-28% of yeast cell walls, 0.05% of a mildewproof agent and a carrier (montmorillonite powder). The method for preparing the nanoscale traditional Chinese medicine feed additive comprises the following steps of firstly calibrating a platform scale, and collecting corresponding raw materials; accurately weighing the raw materials according to the formula, adding the weighed raw materials to a mixing machine in the sequence that large raw materials are firstly added, and then small raw materials are added, and performing thorough mixing; then performing dustless homogenizing treatment; and enabling fine materials to enter a packing working procedure for packing, then performing checking and accepting and performing warehousing.
Description
Technical field
The present invention relates to a kind of nanoscale Chinese medicine feed additive being conducive to raising female animal to oestrus and preparation method thereof.Belong to the technical field of animal and veterinary
Background technology
Along with pig industry from traditional, scattered feeding manner to scale, batch production development, the height of culture benefit is key problem of concern, and the biggest obstacle of current aquaculture development is that female animal Oestrus rate is low, still birth rate is high, farrowing is few.Reason is mainly by feed mold, and the feed nutrition that the factor such as environmental stress causes is too low or nutrition is unbalanced causes.The present invention is directed to these situations develop product that a kind of efficient regulation breeding stock oestruses-, can effectively solve problem above, improve breeding stock reproductive performance, extend the service life of breeding stock.This increases benefit for numerous raisers and reduces the key of cost.
When brood matron occurs without and oestruses phenomenon, first have to difference situation, treat respectively, i.e. to older or suffer from chronic genital diseases, again without Seed practical value should carry out eliminate process；The thinnest to the growth of livestock, the bad female animal of nutriture should be by regulating the way of daily ration, and the nutrient substance that supply is sufficient particularly should meet the needs of its protein, energy and vitamin, promotees its full development and enters and normally oestrus；Can also calculate and grasp the estrus time that the next one is likely to occur, and note observing according to upper calving, farrowing, a lambing time, breed in good time；Young female animal can not be bred too early, after female animal body maturation must be waited, it could be carried out rutting
If the female animals such as cow, sow, ewe are affected by factors such as physiology, nutrition, disease, ages, frequently can lead to atypical estrus, as do not found in time, conscientiously identify, diagnoses and treatment, it will be delayed breeding, make brood matron can not bring benefit to raiser as scheduled.Therefore the nanoscale Chinese medicine preparation that research raising female animal oestruses has important practical significance.
Summary of the invention
It is an object of the invention to provide a kind of nanoscale Chinese medicine feed additive being conducive to raising female animal to oestrus and preparation method thereof.For improving crush efficiency and effect, the present invention uses high-speed impact power and shearing force, makes material be extruded by medium in mill tube, kneading and tear act on, and greatly shortens grinding time, improves crush efficiency；Simultaneously being fluidization because of material and each granule has identical stress, its own viscous effect can make finished product be formed to be uniformly dispersed and the cloud of micro-particles of accurate Composite, increase degree of compaction and improve bioavailability, improving Crushing of Ultrafine effect and technology.Play natural Chinese medicine and the Synergistic of functional additive, the feature of harmonizing simultaneously, be beneficial to improve female animal and oestrus.
Realize the technical scheme that foregoing invention purpose takes as follows:
The present invention provides a kind of being conducive to improve the nanoscale Chinese medicine feed additive that female animal oestruses, and is made up of as following weight percent following component: Chen Ai 15-25%, Herba Leonuri 20-50%, Radix Angelicae Sinensis 3-5%, calcium chloride 20%-33%, glucose 15%-28%, yeast cell wall 22%-28%, antifungus agent 0.05%, carrier (montmorillonite powder).
A kind of being conducive to of the present invention improves the nanoscale Chinese medicine feed additive that female animal oestruses, and needed raw material component can commercially be buied.
Described Chen Ai is and is Chinese mugwort, Chinese mugwort punt-pole, and Compositae herbaceos perennial, China's majority area has, the wildest.Stem, leaf contain aromatic oil, as far back as the 17th century, Chinese mugwort the most just can be used as perfumery raw material, be also used to kill. as additive, for brew Artemisia absinihium L beer worm and prevention and elimination of disease and pests.Regulate the flow of vital energy blood, by cold-damp；Warming the meridian, hemostasis, antiabortive.Control trusted subordinate's cold type of pain, convulsion of having loose bowels, chronic dysentery, tell nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.Folium Artemisiae Argyi has another name called Artemisia argyi, Artemisia argyi Levl. et Van. var. argyi cv. Qiai, Radix Artemisia ordosicae, and nature and flavor are bitter, pungent, warm, enters spleen, liver, kidney channel.Energy dispelling cold and removing dampness, warming the meridian for stopping bleeding.It is applicable to that deficient cold type is hemorrhage and stomachache, has obvious curative effects for women's deficiency and coldness menoxenia, stomachache, metrorrhagia, be a kind of gynecological good medicine.The most just the when of Folium Artemisiae Argyi listing, Folium Artemisiae Argyi can be cooked Chinese mugwort Ci dessert, is processed into various cuisine and medicated diet.Antibacterial action: moxa roll sootiness still can reduce the antibacterial of burn wound.Cavia porcellus tuberculosis is after moxibustion treatment, and progression of disease is relatively slow, and pathological changes is relatively light, especially becomes apparent from the course of disease later stage；In addition can also strengthen reticuloendothelial cell phagocytosis reaction, but the degree strengthened when animal acquired immunity notable；The phagocytosis function of Cavia porcellus RE system cell is consistent with the tuberculosis of internal organs, and when liver, spleen are damaged by disease, phagocytosis function i.e. declines.It addition, also have antifungic action, antiasthmatic effect, choleretic effect, suppression platelet aggregation, anastalsis, to the effect in gastrointestinal tract and uterus, to Cardiovascular System, anti-allergic effects etc..
Described Herba Leonuri, Herba Leonuri, have another name called:, motherwort, Herba Leonuri, nine Rhizoma Paridis, the Muscovitum base of a fruit careless, gloomy, Classification system: Leonurus artemisia, for Labiatae, mother wort plant, summer-flowering.Its dry aerial parts are conventional Chinese medicine, and most of China area is all produced, and give birth to or endure cream and use.1 year or biennial herb whole nation most area all have distribution, are born in hill wasteland, ridge, meadow etc..Plucking when the non-standard-sized sheet of riotous growth flower in summer, acrid in the mouth is bitter, cool, invigorates blood circulation, silts of dispelling, regulating menstruation, disappear water, treats menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Herba Leonuri has inducing diuresis to remove edema, shrinks the effect of uterus effect, is that ancient Chinese medicine doctor is for treating gynopathic key medicine.Herba Leonuri can all herbal medicine, effective ingredient is Herba Leonuri element, and Herba Leonuri is containing multiple alkaloid and benzoic acid, the potassium chloride etc. such as leonurine, stachydrine, leonuridine, leonurinine.Motherwort formulation has the effect of excited animal uterus, similar to pituitrin, and Herba Leonuri extractum and decoct have strong and lasting excitation to uterus, not only can strengthen its contractility, can improve its tensity and shrinkage factor simultaneously.
Described Radix Angelicae Sinensis Radix Angelicae Sinensis, (formal name used at school: Angelica sinensis) call dry return, the Qin which, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis, Radix Angelicae Sinensis, Radix Angelicae Sinensis body, contain that Radix Angelicae Sinensis, Radix Angelicae Sinensis be bent, Radix Angelicae Gigatis, perennial herb, high 0.4-1 rice.The month at florescence 6-7, really the phase 7-9 month.China's nineteen fifty-seven introduces a fine variety Radix Levistici Officinalis from Europe.Main product the southeast of Gansu, many with Minxian County yield, quality is good, is secondly that Yunnan, Sichuan, Shaanxi, Hubei etc. save, is cultivation.Some provinces and regions domestic introducing and planting the most.Its root can be used as medicine, and is one of the most frequently used Chinese medicine.There is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, anti-old, immune effect anticancer, anti-ageing.
Described calcium chloride calcium chloride is inorganic compound, a kind of salt being made up of chlorine element and calcium constituent, for typical ion-type halogenide.Character is white, hard fragment or granule.Micro-hardship, tasteless.Calcium chloride has prominent absorbability and low desorption temperature to ammonia, has great application prospect in terms of synthesis ammonia adsorbing separation.But stable porous material it is not easily formed due to calcium chloride, little with the contact area of gas ammonia, and easily expand during Adsorption and desorption, lump, therefore it is allowed to be difficult to be put to actual application in this respect.Calcium chloride is supported on high surface area carrier, the contact area of calcium chloride and gas ammonia can be greatly improved.Existing correlational study shows, calcium chloride supports the compound adsorbent prepared on molecular sieve has more preferable absorption property and stability than single adsorption agent.Calcium chloride, a kind of salt being made up of chlorine element and calcium constituent, chemical formula is CaCl2.It is typical ion-type halogenide, is white solid under room temperature.Its common application includes the saline used by refrigeration plant, road ice melting agent and desiccant.Because it the most easily absorbs moisture generation deliquescence [5], so anhydrous calcium chloride must hermetically storing in a reservoir.Calcium chloride and hydrate and solution thereof all have important using value in many aspects such as food manufacturing, construction material, medical science and biologys.
Described Glucose Glucose sugar (Glucose) (chemical formula C6H12O6) is also called glucose, corn sugar, referred to as glucose.English another name: Dextrose, Cornsugar, Grapesugar, Bloodsugar.Being that distributed in nature is the widest and of paramount importance a kind of monosaccharide, it is a kind of polyhydroxy aldehyde.Pure glucose is clear crystal, and pleasantly sweet but sweet taste is not so good as sucrose (common people cannot taste sweet taste), soluble in water, is slightly soluble in ethanol, insoluble in ether.Aqueous solution optically-active to the right, therefore belongs to " dextrose ".Glucose has critical role in field of biology, is energy source and the metabolism intermediate product of living cells, i.e. biological main energy supply material.Plant can produce glucose by photosynthesis.In candy making industry and field of medicaments extensive application.
The thickness of described yeast cell wall is 0.1～0.3 μm, and weight accounts for the 18%～30% of dry cell weight, is mainly made up of, containing a small amount of protein, fat, mineral D-glucosan and D-mannan two class polysaccharide.About glucosan and the mannan of equivalent accounts for the 85% of cell wall dry weight.When, after cell ageing, cell wall weight can double.Although it has certain toughness, but its tenacity makes the shape that yeast holding is special.Its chemical composition is more special, is mainly made up of yeast cellulose, and its structure is similar to sandwich.Outer layer is mannan, accounts for the 40%～45% of cell wall dry weight.Intermediate layer is one layer of protein molecule, accounts for the 10% of cell wall dry weight.Presented in some of which is the enzyme to combine with cell wall.Internal layer is glucosan.Yeast cell wall itself is the slightly solubility material that cell obtains after multiple enzyme enzymolysis, the product obtained after being collected by centrifugal method.Cell wall itself is rich in abundant somatomedin, such as: sterol, unsaturated chain fatty acid, oleic acid and Palmic acid etc., these materials can promote that cell permeability of the membrane adjusts, and promotes the Fermentation of yeast cells.
It is a further object of the present invention to provide a kind of nanoscale Chinese medicine feed additive being conducive to raising female animal to oestrus and preparation method thereof, comprise the steps:
1, the micronizing of the most various raw materials, different qualities according to various Chinese medicines, sophistication, uses high frequency vibration, make the various Chinese medicine high acceleration by medium in mill tube clash into, learn from each other by exchanging views, extrude, the effect such as cutting, reaches preferable crushing effect in very short time
2, then carry out school to claim, get corresponding raw material；Formulation content is less than the additive (including: various Chinese medicines, glucose, antifungus agent etc.) of 10 kilograms in per ton and adds Component Vectors, individually premixes by drum mixer.Typically it is diluted to the pre-mixing agent of 10%.
3, Chen Ai, Herba Leonuri, Radix Angelicae Sinensis, calcium chloride, glucose, yeast cell wall, antifungus agent, carrier (montmorillonite powder) are accurately weighed according to above-mentioned formula.Deng according to the biggest raw material, the order of rear little raw material, add in mixer, be sufficiently mixed；
4, carry out dustlessization homogenizing to process；
5, each stage material puts into premixing machine, and intermediate period is about one minute, and total incorporation time is 15-20 minute；
6, then powder enters packaging process packaging, final acceptance, warehouse-in.
The invention has the beneficial effects as follows: compound method of the present invention is raw materials used commercially available in market, and this method is simple and easy to operate, be suitable for large-scale production.
A kind of being conducive to using compound method of the present invention to prepare improves the nanoscale Chinese medicine feed additive that female animal oestruses, advantage the most following aspects:
1, it is an object of the invention to the compound use by plurality of Chinese, regulation female animal intestinal health, improve embryo quality, reduce the negative effect of stress, reduce forage poisoning element toxic action, strengthen female animal immunity, thus female animal physiological function is systematically regulated from integral level, improve the sub-health state of female animal, thus improve the Oestrus rate of female animal, and increase female animal service life..
2. add composite mildewproof mildew removing agent green, natural, be inherently eliminated the female animal that feed mold causes and oestrus obstacle disease.
3. in the present invention, motherwort formulation has the effect of excited animal uterus, similar to pituitrin, and Herba Leonuri extractum and decoct have strong and lasting excitation to uterus, not only can strengthen its contractility, can improve its tensity and shrinkage factor simultaneously.
4., owing to using superfine communication technique, product palatability is preferable, can be remarkably reinforced feedstuff palatability, for any threadiness, high tenacity, high rigidity or have the material of certain moisture content to be all suitable for by micronizing.Cryptogam needs to break the Chinese medicine of cell wall, and its sporoderm-broken rate is higher than 98%.Adapt to dry type and case of wet attrition simultaneously.Water, ethanol or other liquid can be added during case of wet attrition.
5. if cost consideration, its price is relatively low, and yield is high, and safety, and product uses in plant, and the Oestrus rate of female animal is close to more than 98%, and economic benefit improves more than 30%.
Therefore, all raw materials of the present invention be all high-quality, efficiently, safely, have no side effect.It it is the product of the pure green promoting oestrus of sow.
Accompanying drawing is compound method process chart detailed description of the invention of the present invention.
Fig. 1 is superfine comminution system, the main Chen Ai to the present invention, Herba Leonuri, the uses high frequency vibration of Radix Angelicae Sinensis, make the various Chinese medicine high acceleration by medium in mill tube clash into, learn from each other by exchanging views, extrude, the effect such as cutting, in very short time, reach preferable crushing effect
In Fig. 1: 1, crushing system, 2, cyclone collector, 3, pulse dust collector, 4, blower fan
Fig. 2 is the structural representation of patent drum mixer mixer of the present invention.All raw materials mainly for the present invention the most uniformly mix.
In Fig. 2: the platform scale (raw material metering) of 1.500kg, 2. blanking hole, 3. cross material screen, 4. dog-house pulse dust collector, 5. bucket elevator, 6. vibrosieve, 7. surge bunker, 8. additive small powder mouth, 9. leaf band Horizontal helical mixer, 10. finished bin, 11. conveying worms, 12. finished product packings, 13. sealing sewing machines, the platform scale (finished product metering) of 14.100kg, 15. discharging opening pulse dust collectors, 16. helical ribbon type cone-type mixers, 17. air compressors
The present invention is further detailed explanation with specific embodiment below in conjunction with the accompanying drawings.
1, the micronizing of the most various raw materials.
2, secondly the various schools that carry out are claimed, get corresponding raw material；
3, formulation content additive (including various Chinese medicine, wandering agent, antifungus agent, antioxidant etc.) less than 10 kilograms in per ton, plus Component Vectors, individually premixes with helical ribbon type cone-type mixer.Typically it is diluted to the pre-mixing agent of 10%,
4, Chen Ai, Herba Leonuri, Radix Angelicae Sinensis, calcium chloride, glucose, yeast cell wall, antifungus agent, carrier (montmorillonite powder) etc. are accurately weighed according to above-mentioned formula, the raw material conversion formula proportion diluted weighs, according to the biggest raw material, the order of rear little raw material, add in leaf band Horizontal helical mixer, be sufficiently mixed；
5, carry out dustlessization homogenizing to process；
6, each stage material puts into leaf band Horizontal helical mixer, and intermediate period is about one minute, and total incorporation time is 15-20 minute；
7, then powder enters packaging process packaging, final acceptance, warehouse-in.
Above-described embodiment is only used as explanation of the invention, limits the present invention never in any form.The case of the technology that every employing is equal to the present invention or equivalent transformation is obtained is all within the scope of the present invention.
Claims (3)
1. the present invention provides a kind of being beneficial to improve nanoscale Chinese medicine feed additive of oestrusing of female animal and preparation method thereof, by following component group as following weight percent
Become: Chen Ai 15-25%, Herba Leonuri 20-50%, Radix Angelicae Sinensis 3-5%, calcium chloride 20%-33%, glucose 15%-28%, yeast cell wall 22%-28%,
Antifungus agent 0.05%, carrier (montmorillonite powder).
A kind of can being conducive in sow feed the most according to claim 1 improves the nanoscale Chinese medicine feed additive that female animal oestruses, and it is characterized in that: institute
State additive to be made up of by weight percentage following component: Chen Ai 15%, Herba Leonuri 20%, Radix Angelicae Sinensis 3%, calcium chloride 20%, glucose 15%, ferment
Blast cell wall 25%, antifungus agent 0.05%, carrier (montmorillonite powder) 2%.
3. a kind of nanoscale Chinese medicine feed additive that raising female animal can be conducive in sow feed to oestrus described in preparation claim 1 and preparation method thereof is:
First carry out micronizing, then various raw material schools are claimed, get corresponding raw material；Then according to above-mentioned formula accurately claims: Chen Ai, Herba Leonuri, Radix Angelicae Sinensis,
Calcium chloride, glucose, yeast cell wall, antifungus agent, carrier (montmorillonite powder).According to the biggest raw material, the order of rear little raw material, add mixer to
In be sufficiently mixed；Process next to that carry out dustlessization homogenizing；Powder enters packaging process, finally carries out an acceptance inspection, puts in storage.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102726621A (en) * | 2012-04-10 | 2012-10-17 | 安佑（中国）动物营养研发有限公司 | Functional feedstuff for solving dystocia and postpartum inflammations of sow |
| CN104027250A (en) * | 2014-04-25 | 2014-09-10 | 江苏华冠生物技术股份有限公司 | Active release processing method for Chinese herbal medicine raw materials |
| CN105125632A (en) * | 2015-09-28 | 2015-12-09 | 成都乾坤动物药业有限公司 | Traditional Chinese medicine composition for treating oestrus delay of female animals as well as preparation method and application of composition |
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2016
- 2016-02-05 CN CN201610080166.8A patent/CN106306371A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102726621A (en) * | 2012-04-10 | 2012-10-17 | 安佑（中国）动物营养研发有限公司 | Functional feedstuff for solving dystocia and postpartum inflammations of sow |
| CN104027250A (en) * | 2014-04-25 | 2014-09-10 | 江苏华冠生物技术股份有限公司 | Active release processing method for Chinese herbal medicine raw materials |
| CN105125632A (en) * | 2015-09-28 | 2015-12-09 | 成都乾坤动物药业有限公司 | Traditional Chinese medicine composition for treating oestrus delay of female animals as well as preparation method and application of composition |
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