CN103393839B - A kind of Chinese prescription and preparation method thereof improving female rabbit breeding production performance - Google Patents

A kind of Chinese prescription and preparation method thereof improving female rabbit breeding production performance Download PDF

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CN103393839B
CN103393839B CN201310293943.3A CN201310293943A CN103393839B CN 103393839 B CN103393839 B CN 103393839B CN 201310293943 A CN201310293943 A CN 201310293943A CN 103393839 B CN103393839 B CN 103393839B
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parts
chinese medicine
rabbit
radix
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CN103393839A (en
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舒刚
明志友
赵小玲
符华林
明佳星
曹飞
吕程
张伟
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SICHUAN RONGZHOU ANIMAL PHARMACEUTICAL Co Ltd
Sichuan Agricultural University
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SICHUAN RONGZHOU ANIMAL PHARMACEUTICAL Co Ltd
Sichuan Agricultural University
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Abstract

The invention discloses a kind of Chinese prescriptions and preparation method thereof for improving female rabbit and breeding production performance, mainly it is to solve to produce above female rabbit constitution decline at present to cause breeding difficulty, farrowing rate low, it is susceptible to suffer from vitamin-deficiency, muscular dystrophy, enterotoxemia and mammitis, the problem for causing young rabbit survival rate low.It is prepared using following Chinese medicine:15 parts by weight of Radix Astragali, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, 15 parts by weight of radix scutellariae, 12.5 parts by weight of matrimony vine, 12.5 parts by weight of Radix Salviae Miltiorrhizae, 10 parts by weight of Herba Epimedii, 10 parts by weight of Cortex Eucommiae, 10 parts by weight of Radix Glycyrrhizae.Above-mentioned Chinese medicine is dried respectively, is then crushed using pulverizing mill, after crossing 200 sieves, is mixed according to aforementioned proportion.Advantage be the present invention can strengthening the spleen and replenishing qi, reinforce the kidney liver protection with nourishing the fetus member, heat clearing and tranquillizing detoxify, the effect of enhancing tocolysis, female rabbit breeding rate, farrowing rate can be allowed to improve, increase lactation rate, postpartum rate of body weight gain and young rabbit birth weight, weaning weight is set to increase, the survival rate of young rabbit is improved, and improves blood parameters.

Description

A kind of Chinese prescription and preparation method thereof improving female rabbit breeding production performance
Technical field
The present invention relates to the Chinese prescriptions and preparation method thereof for improving female rabbit breeding production performance, belong to livestock reproduction production Field.
Background technology
Man of the world rabbit year number of animals raised is more than 1,500,000,000, and wherein meat rabbit accounts for about 94%, and hair rabbit accounts for 5.8%.Currently, China is As the first Yang Tu big countries in the world, in the yield that 2010 have reached 75.0 ten thousand tons, hence it is evident that be higher than other countries[1].It is producing It is found in practice, the survival rate and health status of young rabbit are largely related with the system of female rabbit, milk matter.Contain in female rabbit colostrum There are a large amount of antibody and trace element, young rabbit eats sufficient colostrum in time can enhance autoimmunity, reduce the generation of disease, improve Survival rate.And female rabbit is all cage in production process, the lack of exercise of female rabbit, and female rabbit spleen and stomach function is caused to weaken, deficiency of qi and blood, Cause female rabbit constitution to decline, is susceptible to suffer from vitamin-deficiency, muscular dystrophy, enterotoxemia and mammitis.These diseases have three big Harm:First, it easily causes female rabbit miscarriage, fetal anomaly, stillborn foetus, change tire or infertile[2];Second, easily suffer from nursing period son rabbit Common disease, such as yellow urine disease, colibacillosis, young rabbit pyaemia septica, cause growth retardation even dead;Third is difficult To ensure the health status of female rabbit, to influence female rabbit lactation amount and female rabbit colostrum quality so that the survival rate of young rabbit obtains Less than guarantee.So the survival rate of healthy a farrowed rabbit of female rabbit female farrowed rabbit of rabbit usually more poor than constitution of the same age Survival rate is high.In production practice, it is mostly used other than drug therapy and adds the side such as vitamin, trace element in right amount in feed Method, to be expected that by raising Abwehrkraft des Koepers, the enough vitamin of supplement and trace element, adjust and mitigate stressor effect, adjusting Gastrointestinal motility, it is anti-inflammatory the effects that improve female rabbit physiological function, so as to improve the constitution of female rabbit and young rabbit, improve the production of female rabbit Performance.
Chinese medicine has peculiar advantage and significant curative effect with its distinctive advantage to the disease.Using Radix Astragali, Rhizoma Atractylodis Macrocephalae, Huang in practice A kind of reed mentioned in ancient books, matrimony vine, Radix Salviae Miltiorrhizae, Herba Epimedii, Cortex Eucommiae, Radix Glycyrrhizae carry out feeding female rabbit, and being shown in clinical has female rabbit breeding production performance The incomparable advantage of chemicals and significant effect.The raising of female rabbit is cage, lack of exercise, and spleen and stomach function subtracts It is weak, deficiency of qi and blood.Deficiency of spleen-QI then can be eaten or not eat, deficiency of vital energy and blood less, and nutrition uterus is unable to, even the debility of chong and ren channels, leads to tire Dynamic uneasiness.Radix Astragali, Rhizoma Atractylodis Macrocephalae strengthening the spleen and replenishing qi in side;The fruit of Chinese wolfberry, Radix Salviae Miltiorrhizae, Herba Epimedii, Cortex Eucommiae reinforce the kidney liver protection with nourishing the fetus member;Again because of rabbit The effect of body temperature is higher, and heat dissipation is insufficient, then adds radix scutellariae heat-clearing calmness, the tocolysis with enhancing same with Rhizoma Atractylodis Macrocephalae;Radix Glycyrrhizae QI invigorating is adjusted in With all medicines, the above 8 taste Chinese medicine brings out the best in each other, treating both manifestation and root cause of disease, not only can be with warming kidney and strengthening spleen, promoting blood circulation for regulating menstruation, warm the womb progestogenic, blood-nourishing peace Tire, moreover it is possible to improve female rabbit disease resistance, promote lactation and other effects.The product has cost relatively low, easy to use, significant effect etc. Feature.
Currently, Chinese medicine is widely used in foster rabbit produces, producer is mostly produced with States Pharmacopoeia specifications prescription.Rabbit Chinese medicine For type mostly based on powder, Chinese medicine is mainly crushed general oral powder according to certain requirement should be by 80~100 mesh Sieve tends not to adequately to release active ingredient and delay treating time but since drug smashing fineness is inadequate in enteron aisle.It adopts It was carried out after being micronized 300 mesh sieve with Chinese medicine, the particle size range of Chinese medicine is 45um or so, within this range contained by particle Chinese medicine Compared with traditional Chinese medicine medicine materical crude slice, Chinese medicine preparation the variation on apparent molecular structure will not occur for effective substance, no The change that can lead to Chinese medicine attribute, pharmacodynamic properties and major function provides basic guarantee for herbal medicine efficacy and stabilization.Meanwhile Chinese medicine, which is crushed to 45um or so, has made cell rupture, and the effective ingredient in broken cells can all directly be absorbed by animal, And most cells are complete in general pulverized particles and medicine materical crude slice, particle is by the even more groups of cells of several, dozens of At, in cell the dissolution of effective medicinal component need guiding through several or even dozens of cell wall could enter animal body in, then by Animal absorbs, and quite a few Cell Component can not possibly enter across cell wall in animal body, this part can only be in vain It throws away.Therefore, it the effective ingredient emission of ultrafine Chinese herb and disengages speed, absorbs the amount of medicament effective component all in the unit interval Can be higher than the herb powder that Ordinary pulverization method is obtained, the type of the medicament effective component disengaged is also than Ordinary pulverization side Method is complete, and the drug effect time can significantly shorten, and acts on more comprehensively, action intensity higher.Drug enter after animal body first have to through The effect of internal profitable strain, since micro-powder of Chinese herbs particle is small, the effect of profitable strain can be rapider, stronger, makees through flora The magnitude and concentration of product can significantly improve, this is also advantageous for the absorption of animal, improve absorption intensity, what we used The amount of Chinese medicine also greatly reduces.
Invention content
The present invention relates to a kind of Chinese prescriptions and preparation method thereof for improving female rabbit and breeding production performance, it is characterized in that according to The raising of female rabbit is cage, lack of exercise, spleen and stomach function decrease, deficiency of qi and blood;Deficiency of spleen-QI then can be eaten or not eat, gas less Anemia is damaged, and nutrition uterus is unable to, even the debility of chong and ren channels, the case where leading to fetal irritability, according to Chinese veterinarian's traditional theory with warm kidney Invigorating the spleen, promoting blood circulation for regulating menstruation, warm the womb progestogenic, nourishing blood and preventing abortion, clearing heat and detoxicating principle carry out prescription.And by following weight raw material Radix Astragali 15 Parts by weight, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, 15 parts by weight of radix scutellariae, 12.5 parts by weight of matrimony vine, 12.5 parts by weight of Radix Salviae Miltiorrhizae, 10 weight of Herba Epimedii Part, 10 parts by weight of Cortex Eucommiae, 10 parts by weight of Radix Glycyrrhizae, carrying out micro mist pulverization becomes the micro mist of 45 μm or so sizes.Prescription of the present invention The effect of energy strengthening the spleen and replenishing qi, liver protection of reinforcing the kidney are detoxified with nourishing the fetus member, heat clearing and tranquillizing, enhanced tocolysis, can also enhance can also improve mother Rabbit disease resistance, the survival rate for promoting lactation, promoting young rabbit.Prescription effectively avoid it is big using chemical classes drug side-effect, There is the shortcomings that residual, improves powder spice effect, absorption difference and the big problem of usage amount, the mesh of rapid-onset can be reached 's.
Breeding starts to young rabbit to wean on the 15th day after being successfully pregnant with female rabbit within first 10 days adds this Chinese prescription, every female rabbit 0.5 gram is used daily.
Advantages of the present invention:Radix Astragali, Rhizoma Atractylodis Macrocephalae strengthening the spleen and replenishing qi in side;The fruit of Chinese wolfberry, Radix Salviae Miltiorrhizae, Herba Epimedii, Cortex Eucommiae reinforce the kidney liver protection with Nourishing the fetus member;The effect of again because rabbit body temperature is higher, heat dissipation is insufficient, then adds radix scutellariae heat clearing and tranquillizing, the tocolysis with enhancing same with Rhizoma Atractylodis Macrocephalae; Radix Glycyrrhizae QI invigorating and in, coordinating the drug actions of a prescription, the above 8 taste Chinese medicine brings out the best in each other, treating both manifestation and root cause of disease, can not only enhance strengthening the spleen and replenishing qi, blood-nourishing Tocolysis, moreover it is possible to improve female rabbit disease resistance, promote female rabbit galactosis, improve the survival rate of young rabbit.Meanwhile the prescription has The features such as source is easy to get, cost is relatively low, easy to use, significant effect.
Specific implementation mode
Below in conjunction with specific embodiment, the present invention is described in detail.
Embodiment 1
According to 15 parts by weight of Radix Astragali, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, 15 parts by weight of radix scutellariae, 12.5 parts by weight of matrimony vine, 12.5 weight of Radix Salviae Miltiorrhizae Amount part, 10 parts by weight of Herba Epimedii, 10 parts by weight of Cortex Eucommiae, 10 parts by weight of Radix Glycyrrhizae are weighed Chinese herbal medicine;For example, taking Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 15g, radix scutellariae 15g, matrimony vine 12.5g, Radix Salviae Miltiorrhizae 12.5g, Herba Epimedii 10g, Cortex Eucommiae 10g, Radix Glycyrrhizae 10g, carrying out micro mist pulverization becomes The micro mist of 45 μm or so sizes, mixing pack sealing is spare to improve the Chinese prescription that female rabbit breeds production performance to get the present invention.
This product is (1) fineness:95% should be sieved by No. 9.(2) body colour:For brownish-yellow powder;Gas faint scent, mildly bitter flavor.It is dry Dry, loose to dredge, is uniformly mixed, color and luster is consistent.(3) it stores:General powder answers closed storage, containing the strong powder of volatile oil or moisture absorption It should be sealed and stored.(4) uniformity:Suitable powder is taken, is placed in glossy paper and tiles about 5 square centimeters, its surface is flattened, Bright place's observation, is presented uniform color and luster, no decorative pattern and color spot.(5) moisture inspection:No more than 9%.
Embodiment 2
Healthy adult mother rabbit 48,2.5 kilograms or so of weight are randomly divided into 4 groups, and every group of 3 repetitions are each to repeat 4. Wherein all groups use same basic daily ration, control group fed basal diet;Common Chinese dissipates smooth group of fowl (containing Radix Astragali, Radix Codonopsis, ripe Ground, 60 mesh of smashing fineness sieve) 1.2 grams of the feeding daily of every rabbit, chemical drug stress plain group (containing vitamin A. D. E) every rabbit it is daily 0.2 gram of feeding, certainly quasi- Chinese prescription group, breeding start to the wean of young rabbit to add on the 15th day after being successfully pregnant with female rabbit within first 10 days, 0.5 gram of the feeding daily of every rabbit.Enter experimental period after preliminary trial period, experimental period 65d, 25d is disconnected after being set as young rabbit birth Milk, female rabbit and free water and feeding.Following result is obtained after the test:
(1) female rabbit breeding, farrowing situation
There is table 1 to find out, control group breeding rate is minimum, and other drugs group is higher than control group.Litter size compares, from quasi- Chinese medicine group Side's group is most, and control group is minimum.
1 fowl of table is smooth, stress it is plain, from quasi- influence of the prescription to female rabbit breeding rate, litter size
(2) influence of each drug to female rabbit lactation amount
As shown in Table 2, each group 14d reaches lactation peak, is then in again downward trend, and 1-21d each group differences are not notable, And when 25d, difference is freely organized with control group, fowl extremely significantly (P < 0.01), improve 146.83%, 68.1% from quasi- Chinese medicine group.From quasi- Chinese medicine group group lactation amount is all higher in each stage.
2 fowl of table is smooth, stress it is plain, from quasi- influence of the prescription Chinese medicine to female rabbit lactation amount
Note:Different capitalization differences are extremely notable (P < 0.01) in same column, different lowercase significant difference (P < 0.05), not marking-up is female or has same letter difference not notable (P > 0.05);Similarly hereinafter.
(3) fowl it is smooth, stress it is plain, from quasi- influence of the prescription Chinese medicine to young rabbit weight, survival rate
As shown in Table 3, when 1d, control group and fowl freely organize difference extremely significantly (P < 0.01), and stress element group significant difference (P < 0.05);From quasi- Chinese medicine group and control group significant difference (P < 0.05), 11.82% is improved.When 21d, control group and fowl are freely, certainly Quasi- Chinese medicine group significant difference (P < 0.05) improves 4.86% from quasi- Chinese medicine group than control group;When 25d, control group and fowl are freely, certainly Quasi- Chinese medicine group difference is extremely notable (P < 0.01), and 10.44% is improved than control group from quasi- Chinese medicine group, and from intending, Chinese medicine group is smooth with fowl, answers Also difference is extremely notable (P < 0.01) for hormone group.Survival rate compares, control group and certainly quasi- Chinese medicine group significant difference (P < 0.05), from Quasi- Chinese medicine group is improved than control group, and 67.30%.
3 fowl of table is smooth, stress it is plain, from quasi- influence of the prescription Chinese medicine to young rabbit weight and survival rate
(4) 2.3 fowl are smooth, stress it is plain, from quasi- influence of the prescription Chinese medicine to female rabbit changes of weight
As shown in Table 4, antenatal each group difference is not notable (P > 0.05).Postpartum, from quasi- Chinese medicine group rate of body weight gain and other 3 groups Difference extremely significantly (P < 0.01), from quasi- Chinese medicine group improves 41.67 times than control group;When wean, also significant difference (P < 0.05), From quasi- Chinese medicine group 1.93 times are improved than control group.
4 fowl of table is smooth, stress it is plain, from quasi- influence of the prescription Chinese medicine to female rabbit weight
(5) fowl it is smooth, stress it is plain, from quasi- influence of the prescription Chinese medicine to female rabbit biochemical indicator
As shown in Table 5, from quasi- Chinese medicine group glutamic-oxalacetic transaminease and control group significant difference (P < 0.05), from quasi- Chinese medicine group ratio Control group reduces by 13.14%;Glutamic-pyruvic transaminase each group difference is not notable, stress plain group, from quasi- Chinese medicine group total cholesterol and compare Group significant difference (P < 0.05) reduces by 52.56% from quasi- Chinese medicine group than control group, and triglycerides compares also significant difference (P < 0.05), 21.79% is reduced than control group from quasi- Chinese medicine group.
5 fowl of table is smooth, stress it is plain, from quasi- influence of the prescription Chinese medicine to female rabbit biochemical indicator
Addition significantly improves the lactation amount of female rabbit, postpartum rate of body weight gain and young rabbit from quasi- prescription Chinese medicine pole compared with the control group Birth weight, weaning weight (P < 0.01), significantly improve the survival rate (P < 0.05) of young rabbit, and significantly reduce millet straw in serum and turn The content (P < 0.05) of ammonia enzyme, total cholesterol, triglyceride.The breeding productivity of female rabbit can be significantly improved from quasi- prescription Chinese medicine Energy.
It should be understood that for those of ordinary skills, it can be modified or changed according to the above description, And all these modifications and variations should all belong to the protection domain of appended claims of the present invention.

Claims (2)

1. a kind of Chinese medicine composition for improving female rabbit breeding production performance, which is characterized in that prepared using following Chinese medicine: 15 parts by weight of Radix Astragali, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, 15 parts by weight of radix scutellariae, 12.5 parts by weight of matrimony vine, 12.5 parts by weight of Radix Salviae Miltiorrhizae, Herba Epimedii 10 Parts by weight, 10 parts by weight of Cortex Eucommiae, 10 parts by weight of Radix Glycyrrhizae, are dried above-mentioned Chinese medicine, are then carried out using pulverizing mill respectively It crushes, after crossing 200 mesh sieve, is mixed according to aforementioned proportion.
2. a kind of preparation method for the Chinese medicine composition improving female rabbit breeding production performance, it is characterised in that:Radix Astragali 15 is taken respectively Parts by weight, 15 parts by weight of Rhizoma Atractylodis Macrocephalae, 15 parts by weight of radix scutellariae, 12.5 parts by weight of matrimony vine, 12.5 parts by weight of Radix Salviae Miltiorrhizae, 10 weight of Herba Epimedii Part, 10 parts by weight of Cortex Eucommiae, 10 parts by weight of Radix Glycyrrhizae are dried, and are then carried out reusing micro-powder crusher after thick grade crushing and are surpassed Crushing of Ultrafine reaches 45 μm, is mixed according to aforementioned proportion after crossing 300 mesh sieve.
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CN104082553A (en) * 2014-06-10 2014-10-08 芜湖县绿色草原兔业养殖专业合作社 Rabbit feed used in gestation period and preparation method thereof
CN104887821A (en) * 2015-06-25 2015-09-09 李春燕 Medicine for increasing rabbit reproduction rate
CN105941955A (en) * 2016-06-21 2016-09-21 山东新希望六和集团有限公司 Feed additive for female rabbit raising
CN108522853A (en) * 2018-07-09 2018-09-14 山东龙昌动物保健品有限公司 Application of the eucommia leaf extract in preparing the feed addictive for improving female rabbit reproductive performance
CN111053807A (en) * 2020-02-11 2020-04-24 内蒙古农业大学 Traditional Chinese medicine preparation for preventing and treating dog threatened abortion and preparation method thereof
CN112293575A (en) * 2020-10-26 2021-02-02 辽宁农业职业技术学院 Compound feed additive for improving reproductive performance of cashmere goat ewes and preparation method thereof

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CN102526552A (en) * 2010-12-09 2012-07-04 天津中敖生物科技有限公司 Traditional Chinese medicine composition with function of improving production performance of poultry, and preparation method thereof

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CN102526552A (en) * 2010-12-09 2012-07-04 天津中敖生物科技有限公司 Traditional Chinese medicine composition with function of improving production performance of poultry, and preparation method thereof

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