CN108522853A - Application of the eucommia leaf extract in preparing the feed addictive for improving female rabbit reproductive performance - Google Patents

Application of the eucommia leaf extract in preparing the feed addictive for improving female rabbit reproductive performance Download PDF

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Publication number
CN108522853A
CN108522853A CN201810747803.1A CN201810747803A CN108522853A CN 108522853 A CN108522853 A CN 108522853A CN 201810747803 A CN201810747803 A CN 201810747803A CN 108522853 A CN108522853 A CN 108522853A
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CN
China
Prior art keywords
female rabbit
eucommia leaf
leaf extract
eucommia
reproductive performance
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Pending
Application number
CN201810747803.1A
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Chinese (zh)
Inventor
李金宝
曹爱智
娄倩倩
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Shandong Long Chang Animal Health-Care Product Co Ltd
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Shandong Long Chang Animal Health-Care Product Co Ltd
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Priority to CN201810747803.1A priority Critical patent/CN108522853A/en
Publication of CN108522853A publication Critical patent/CN108522853A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/111Aromatic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/121Heterocyclic compounds containing oxygen or sulfur as hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/50Feeding-stuffs specially adapted for particular animals for rodents

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides application of the eucommia leaf extract in preparing the feed addictive for improving female rabbit reproductive performance.The present invention is using New Zealand mother rabbit as research object, study influence of the eucommia leaf extract to its reproductive performance, eucommia leaf extract provided by the invention contains Cortex Eucommiae chlorogenic acid, eucommia bark flavone and eucommia bark polycose, has effects that antibacterial, resisting stress, anti-oxidant, removing free radical, promotes intestinal beneficial bacterium proliferation, improves immunity of organisms and promote heat and prevent miscarriage.The present invention shows that eucommia leaf extract is added in Brood doe daily ration can significantly improve female rabbit reproductive performance, increase economic benefit by experimental studies results.

Description

Eucommia leaf extract is in preparing the feed addictive for improving female rabbit reproductive performance Application
Technical field
The invention belongs to animal feed additive technical fields, and in particular to eucommia leaf extract is being prepared for improving mother Application in the feed addictive of rabbit reproductive performance.
Background technology
Rabbit reproductive capacity is that rabbit produces the most important first purpose, and female rabbit reproductive capacity is directly related to the height of production level Low and economic benefit quality, therefore it is enlarged reproduction and the basis increased economic efficiency to improve reproductive capacity.
From eucommia leaf extract is extracted by natural folium cortex eucommiae, to various pathogens and infection of the upper respiratory tract Causative virus etc. With significant inhibiting effect.Extracorporeal bacteria inhibitor test shows can be to staphylococcus aureus, beta streptococcus, Escherichia coli There is good inhibiting effect with typhoid bacillus etc..In addition can also strengthen immunity, remove free radical and other effects.In addition, flavones, Polysaccharide isoreactivity ingredient, it is different to immune system, internal system, central nervous system, the circulatory system and urinary system The adjustment effect of degree.
Invention content
The object of the present invention is to provide eucommia leaf extracts to prepare the feed addition for improving female rabbit reproductive performance Application in agent.Using New Zealand mother rabbit as research object, influence of the research eucommia leaf extract to its reproductive performance is the present invention Effectiveness of the eucommia leaf extract in terms of improving female rabbit reproductive capacity provides scientific basis.
For achieving the above object, the present invention is achieved by the following scheme:
The present invention provides application of the eucommia leaf extract in preparing the additive for improving female rabbit reproductive performance.
Further:The eucommia leaf extract contains following components:Cortex Eucommiae chlorogenic acid 3%-8%, eucommia bark flavone 8%- 16% and eucommia bark polycose 20%-40%.
Further:The preparation method of the eucommia leaf extract includes the following steps:It takes folium cortex eucommiae to be extracted with water, extracts 55-65 DEG C of temperature, extraction time 2-4h, is then filtered, and filtrate is taken to be concentrated in vacuo to proportion 1.2 at 60 DEG C, through spraying The eucommia leaf extract is made in drying tower spray drying.
Further:Additive amount of the eucommia leaf extract in female rabbit daily ration is 150g/t-250g/t.
Further:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the nest production for significantly improving female rabbit is living young Number.
Further:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the weigth at birth of female rabbit is significantly improved.
Further:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the 21 age in days nests of female rabbit are significantly improved Weight.
Further:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the 30 age in days nests of female rabbit are significantly improved Weight.
Further:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the farrowing rate of female rabbit is significantly improved.
Compared with prior art, it advantages of the present invention and has the technical effect that:Eucommia leaf extract provided by the invention is containing Du Secondary chlorogenic acid, eucommia bark flavone and eucommia bark polycose have antibacterial, resisting stress, anti-oxidant, remove free radical, promote intestinal beneficial bacterium Proliferation improves immunity of organisms, the effect of promoting heat and prevent miscarriage.The present invention is shown by experimental studies results in Reproductive Female Eucommia leaf extract is added in rabbit daily ration can significantly improve female rabbit reproductive performance, increase economic benefit.
Specific implementation mode
Further detailed description is done to technical scheme of the present invention with reference to specific embodiment.
Embodiment 1
1 material and method
Selection, grouping and the experimental period of 1.1 experiment rabbits
Select age and weight close, the first-born is normal, the New Zealand mother rabbit 120 of genital tract health after childbirth, random point It is rented for control group and experiment, every group 60, every group of 3 repetitions, it is each to repeat 20.Control group fed basal diet, test group The same basal diet of feeding addition 200g/t eucommia leaf extracts.Experiment is since after the first-born childbirth, the wean of the second fetus rabbit When terminate, 105 days experimental periods.
1.2 test periods, place and trial target
Test period:2 months 21-June 5 in 2014,105 days experimental periods.
Test site:Sichuan Agricultural University's teaching and scientific research warren.
The preparation method of the eucommia leaf extract includes the following steps:Folium cortex eucommiae is taken to be extracted with water, Extracting temperature 55-65 DEG C, then extraction time 2-4h is filtered, filtrate is taken (to select this temperature extraction, it is possible to reduce the damage of chlorogenic acid at 60 DEG C Lose, and recovery rate highest) be concentrated in vacuo to proportion 1.2 (be concentrated to the solution of this proportion, the time used in spray drying is most short, because For chlorogenic acid pyrolytic, the spray drying used time is short, and chlorogenic acid moment spray drying is not lost, and energy saving) spray-dried tower The eucommia leaf extract is made in spray drying.
Eucommia leaf extract obtained contains:Chlorogenic acid 5%, eucommia bark polycose 20%, eucommia bark flavone 8%, by quality ratio.
1.3 experimental design
It is designed using single-factor random experiment, the feed of feeding is identical with trophic level, control group fed basal diet, examination Test a group addition 200g/t eucommia leaf extracts.
1.4 Diet Formulas and trophic level
1 Diet Formula of table and trophic level
1.5 feeding managements are measured with experiment
Every morning 8 cleanings, 9 points start to feed.Free choice feeding and free water.
Start to feed after the childbirth of the first tire of female rabbit, the wean of 30 age in days of young rabbit, postweaning estrus breeding.Using spontaneous estrus, Human assistance is bred.The rabbit of heat breeds in 15 days after wean, still continues to breed in 15 days if returning feelings after breeding, after 15 days not It breeds again.Abortion situation is observed during experiment, measures nest litter size, the number of live birth, death toll, weigth at birth, 21 ages in days Litter weight and 30 age in days litter weights.
2 testing indexs
2.1 nest litter sizes
Nest litter size:Litter size of the nascent per nest, including stillborn foetus, monster.
2.2 the number of live birth
The number of live birth:Young number living in 12 hours nascent per nest.
2.3 weigth at birth
Weigth at birth:The total weight of young number living in 12 hours nascent per nest.
2.421 age in days litter weight
21 age in days litter weights:Total weight of 21 ages in days per nest rabbit (containing rabbit is entrusted one's child to the care of sb.).
2.530 age in days litter weight
30 age in days litter weights:Total weight of 30 ages in days per nest rabbit.
2.6 farrowing rate
Farrowing rate=farrowing mother rabbit number/breeding season internal reference matches female rabbit number.
2.7 young rabbit survival rate
Young rabbit number/nascent total young rabbit number living always living when young rabbit survival rate=30 age in days.
3 statistical analyses
It is for statistical analysis using SPASS softwares, carry out one-way analysis of variance with ANOVA.
4 results and analysis
2 reproductive performance of table compares
Note:Same column data alphabet difference person indicates significant difference (p < 0.05)
The experimental results showed that:Test group items reproductive performance is superior to control group, the number of live birth of test group, just Raw litter weight, 21 age in days litter weights, 30 age in days litter weights, farrowing rate are all remarkably higher than control group (p < 0.05).Test group farrowing rate compares 8.4% is improved according to group, the number of live birth improves 0.9/nest.
Eucommia leaf extract chlorogenic acid containing Cortex Eucommiae, eucommia bark flavone and eucommia bark polycose have antibacterial, resisting stress, anti-oxidant, clearly Except free radical, the effect of promoting intestinal beneficial bacterium proliferation, improve immunity of organisms, promote heat and prevent miscarriage.This result of study table Bright, eucommia leaf extract is added in Brood doe daily ration can significantly improve female rabbit reproductive performance, increase economic benefit, it is proposed that female Eucommia leaf extract additive amount is 200g/t in rabbit daily ration.
The above embodiments are merely illustrative of the technical solutions of the present invention, rather than is limited;Although with reference to aforementioned reality Applying example, invention is explained in detail, for those of ordinary skill in the art, still can be to aforementioned implementation Technical solution recorded in example is modified or equivalent replacement of some of the technical features;And these are changed or replace It changes, the spirit and scope for claimed technical solution of the invention that it does not separate the essence of the corresponding technical solution.

Claims (9)

1. application of the eucommia leaf extract in preparing the additive for improving female rabbit reproductive performance.
2. eucommia leaf extract according to claim 1 answering in preparing the additive for improving female rabbit reproductive performance With, it is characterised in that:The eucommia leaf extract contains following components:Cortex Eucommiae chlorogenic acid 3%-8%, eucommia bark flavone 8%-16% and Du Secondary polysaccharide 20%-40%.
3. eucommia leaf extract according to claim 1 answering in preparing the additive for improving female rabbit reproductive performance With, it is characterised in that:The preparation method of the eucommia leaf extract includes the following steps:Folium cortex eucommiae is taken to be extracted with water, extraction temperature 55-65 DEG C of degree, then extraction time 2-4h is filtered, filtrate is taken to be concentrated in vacuo to proportion 1.2 at 60 DEG C, dry through spraying The eucommia leaf extract is made in dry tower spray drying.
4. eucommia leaf extract according to claim 1 answering in preparing the additive for improving female rabbit reproductive performance With, it is characterised in that:Additive amount of the eucommia leaf extract in female rabbit daily ration is 150g/t-250 g/t.
5. eucommia leaf extract according to claim 1 answering in preparing the additive for improving female rabbit reproductive performance With, it is characterised in that:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the number of live birth of female rabbit is significantly improved.
6. eucommia leaf extract according to claim 1 answering in preparing the additive for improving female rabbit reproductive performance With, it is characterised in that:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the weigth at birth of female rabbit is significantly improved.
7. eucommia leaf extract according to claim 1 answering in preparing the additive for improving female rabbit reproductive performance With, it is characterised in that:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the 21 age in days litter weights of female rabbit are significantly improved.
8. eucommia leaf extract according to claim 1 answering in preparing the additive for improving female rabbit reproductive performance With, it is characterised in that:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the 30 age in days litter weights of female rabbit are significantly improved.
9. eucommia leaf extract according to claim 1 answering in preparing the additive for improving female rabbit reproductive performance With, it is characterised in that:After adding 200g/t eucommia leaf extracts in female rabbit daily ration, the farrowing rate of female rabbit is significantly improved.
CN201810747803.1A 2018-07-09 2018-07-09 Application of the eucommia leaf extract in preparing the feed addictive for improving female rabbit reproductive performance Pending CN108522853A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113662103A (en) * 2021-08-26 2021-11-19 四川省畜牧科学研究院 Composition for improving reproductive performance of female rabbits and application and method thereof
CN114009591A (en) * 2021-12-17 2022-02-08 湖南德诺健康产业集团有限公司 Natural feed additive for improving growth performance and meat quality of livestock and poultry and application thereof

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CN102228133A (en) * 2011-06-15 2011-11-02 曹爱智 Folium cortex eucommiae extract and application thereof
CN103393839A (en) * 2013-07-05 2013-11-20 四川农业大学 Traditional Chinese medicine formula capable of improving breeding production property of female rabbits and preparation method thereof
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CN105767563A (en) * 2016-03-11 2016-07-20 四川农业大学 Feed for reducing immature-rabbit diarrhea diseases and feeding method of immature rabbit thereof
CN106721367A (en) * 2016-11-28 2017-05-31 四川农业大学 Improve mixed feed of female rabbit reproductive performance and preparation method thereof and method for breeding
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CN102228133A (en) * 2011-06-15 2011-11-02 曹爱智 Folium cortex eucommiae extract and application thereof
CN103393839A (en) * 2013-07-05 2013-11-20 四川农业大学 Traditional Chinese medicine formula capable of improving breeding production property of female rabbits and preparation method thereof
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CN105767563A (en) * 2016-03-11 2016-07-20 四川农业大学 Feed for reducing immature-rabbit diarrhea diseases and feeding method of immature rabbit thereof
CN106721367A (en) * 2016-11-28 2017-05-31 四川农业大学 Improve mixed feed of female rabbit reproductive performance and preparation method thereof and method for breeding
CN107865190A (en) * 2017-12-12 2018-04-03 四川农业大学 Improve meat rabbit growth performance and the mixed feed of weaning period son's rabbit survival rate and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113662103A (en) * 2021-08-26 2021-11-19 四川省畜牧科学研究院 Composition for improving reproductive performance of female rabbits and application and method thereof
CN114009591A (en) * 2021-12-17 2022-02-08 湖南德诺健康产业集团有限公司 Natural feed additive for improving growth performance and meat quality of livestock and poultry and application thereof

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