CN103393839A - Traditional Chinese medicine formula capable of improving breeding production property of female rabbits and preparation method thereof - Google Patents
Traditional Chinese medicine formula capable of improving breeding production property of female rabbits and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine formula capable of improving breeding production property of female rabbits and a preparation method thereof, mainly aiming at solving the problems that due to the reduction of habitus, the produced female rabbits are difficult to mate, low in farrowing rate, liable to have hypovitaminosis, malnutrition, enterotoxaemia and mastitis and further cause low survival rate of newborn rabbits. The traditional Chinese medicine formula is prepared by adopting the following traditional Chinese medicinal materials in parts by weight: 15 parts of radix astragali, 15 parts of rhizoma atractylodis macrocephalae, 15 parts of radix scutellariae, 12.5 parts of fructus lycii, 12.5 parts of radix salviae miltiorrhizae, 10 parts of herba epimedii, 10 parts of eucommia ulmoide and 10 parts of liquorice. The preparation method comprises the steps of respectively drying the traditional Chinese medicinal materials, then grinding by using a microgrinder, a filtering with a 200-mesh sieve, and mixing according to the proportion. The traditional Chinese medicine formula has the advantages of achieving the effects of invigorating spleen and supplementing qi, reinforcing the kidney and protecting the liver so as to nourish the fetus, clearing away the heat and soothing the nerves and removing toxin and enhancing the miscarriage prevention, and is capable of improving the breeding rate and farrowing rate of female rabbits, enhancing lactation rate, increasing the postpartum weight gain rate, the birth weight and weaning weight of newborn rabbits, promoting the survival rate of the newborn rabbits and improving the blood biochemical index.
Description
Technical field
The present invention relates to Chinese prescription that improves female rabbit propagation production performance and preparation method thereof, belong to the livestock reproduction production field.
Background technology
The world man number of animals raised rabbit year surpasses 1,500,000,000, and wherein meat rabbit accounts for 94%, and the hair rabbit accounts for 5.8%.At present, China has become in the world first supports rabbit big country, in 2010, has reached the output of 75.0 ten thousand tons, apparently higher than other countries
[1].In production practices, find, the survival rate of young rabbit is relevant with system, the milk matter of female rabbit to a great extent with health status.Female rabbit just contains a large amount of antibody and trace element in Ruzhong, and young rabbit in time eats sufficient colostrum can strengthen autoimmunity, reduces the generation of disease, improves survival rate.And female rabbit is all raised in cages in production process, and the hypomotility of female rabbit causes female rabbit spleen and stomach function to weaken, and deficiency of qi and blood causes female rabbit body constitution to descend, and easily suffers from avitaminosis, muscular dystrophy, enterotoxemia and mastitis.These diseases have three harm greatly: the first, easily cause female rabbit miscarriage, fetal anomaly, stillborn fetus, change tire or infertile
[2]The second, easily make age of sucking young rabbit suffer from common disease, as Huang urine disease, colibacillosis, young rabbit pyaemia septica etc., cause even death of growth retardation; The 3rd, be difficult to guarantee the health status of female rabbit, thereby affect the quality of lactation amount and the female rabbit colostrum of female rabbit, make the survival rate of young rabbit can not be guaranteed.So the survival rate of the rabbit that female rabbit farrows of a health the survival rate of female rabbit the farrow rabbit more poor than body constitution of the same age usually is high.In production practices, adopt added the methods such as vitamin, trace element in right amount in feedstuff except Drug therapy, with expectation, by improving Abwehrkraft des Koepers, supplementary enough vitamin and trace element, the effect of adjusting mitigation stressor, Gastrointestinal motility adjustment, antiinflammatory etc., be used for improving female rabbit physiological function, thereby improve the body constitution of female rabbit and young rabbit, improve the fertility performance of female rabbit.
Chinese medicine has peculiar advantage and significant curative effect with its distinctive advantage to this disease.In practice, apply the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Scutellariae, Fructus Lycii, Radix Salviae Miltiorrhizae, Herba Epimedii, the Cortex Eucommiae, Radix Glycyrrhizae female rabbit of feeding, demonstrate in clinical female rabbit propagation production performance is had to the incomparable advantage of chemicals and significant effect.The raising of female rabbit is raises in cages, its hypomotility, and spleen and stomach function weakens, deficiency of qi and blood.Deficiency of spleen-QI can be eaten less or not eat, and deficiency of both QI and blood can not the nutrition uterus, even the debility of CHONG and REN meridians causes frequent fetal movement.The Radix Astragali, Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI in side; Fructus Lycii, Radix Salviae Miltiorrhizae, Herba Epimedii, the Cortex Eucommiae are reinforced the kidney and are protected the liver with fetus nourishing unit; Because rabbit body temperature is higher, heat radiation is not enough, adds Radix Scutellariae heat clearing away calmness again, with the Rhizoma Atractylodis Macrocephalae, with using, strengthens antiabortive effect; The Radix Glycyrrhizae QI invigorating and in, coordinating the actions of various ingredients in a prescription, above 8 flavor Chinese medicines bring out the best in each other, treating both the principal and secondary aspects of a disease, not only can warming the kidney and strengthening the spleen, promoting blood flow to regulate menstruation, warm palace progestogenic, nourishing blood and preventing abortion, can also improve female rabbit resistance against diseases, promotes the effects such as lactogenic.This product has the characteristics such as cost is lower, easy to use, and effect is remarkable.
At present, Chinese medicine is widely used in foster rabbit produces, and producer produces mainly with pharmacopeia regulation prescription.Rabbit is main with form of Chinese drug mainly with powder, mainly Chinese medicine to be pulverized to general oral powder according to certain requirement should pass through 80～100 mesh sieves, but, because the medicine smashing fineness is inadequate, at intestinal, often can not discharge fully effective ingredient and delay treating time.Adopt Chinese crude drug to carry out after micronization crosses 300 mesh sieves, the particle size range of Chinese medicine is the 45um left and right, at the contained effective substance of this scope endoparticle Chinese medicine, with Chinese medicine decoction pieces, Chinese medicine preparation, compare, will the variation on obvious molecular structure can not occur, the change that can not cause Chinese medicine attribute, pharmacodynamic properties and function to cure mainly, herbal medicine efficacy and the stable basic guarantee that provides are provided.Simultaneously, Chinese medicine is crushed to the 45um left and right and has made cell rupture, active ingredient in the breaking cellular wall cell can all directly be absorbed by animal, and most cells are complete in general pulverized particles and decoction pieces, its particle is comprised of several, the even more cell of dozens of, in cell effectively the stripping of medicinal component need pass several even dozens of cell wall and just can enter in animal body, then by animal, absorbed, and quite a few Cell Component can not pass cell wall and enter in animal body, and this part can only be thrown away in vain.Therefore, the active ingredient emission of ultrafine Chinese herb and disengage speed, the amount of active ingredient of absorbing the drug in unit interval all can be higher than the Chinese medicinal powder that Ordinary pulverization method obtains, the kind of the medicament effective component that it disengages is also complete than Ordinary pulverization method, the drug effect time can significantly shorten, more comprehensively, action intensity is higher in effect.Medicine enter after animal body at first will be in body the effect of profitable strain, because the micro-powder of Chinese herbs particle is little, the effect meeting of profitable strain more rapidly, stronger, value and concentration through the product of flora effect can obviously improve, this also is of value to the absorption of animal, improve absorption intensity, the amount of the Chinese medicine that we use also greatly reduces.
Summary of the invention
The present invention relates to a kind of Chinese prescription that improves female rabbit propagation production performance and preparation method thereof, it is characterized in that raising according to female rabbit is to raise in cages, its hypomotility, spleen and stomach function weakens, deficiency of qi and blood; Deficiency of spleen-QI can be eaten less or not eat, and deficiency of both QI and blood can not the nutrition uterus, even the debility of CHONG and REN meridians causes the situation of frequent fetal movement, according to Chinese veterinarian's traditional theory with warming the kidney and strengthening the spleen, promoting blood flow to regulate menstruation, warm palace progestogenic, nourishing blood and preventing abortion, the principle of heat-clearing and toxic substances removing is carried out prescription.And, by the following weight raw material Radix Astragali 15 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, Radix Scutellariae 15 weight portions, Fructus Lycii 12.5 weight portions, Radix Salviae Miltiorrhizae 12.5 weight portions, Herba Epimedii 10 weight portions, the Cortex Eucommiae 10 weight portions, Radix Glycyrrhizae 10 weight portions, carry out the micropowder that the micropowder pulverization becomes 45 μ m left and right sizes.Prescription energy of the present invention invigorating the spleen and benefiting QI, reinforcing the kidney protects the liver with fetus nourishing unit, heat clearing and tranquillizing detoxifcation, strengthens antiabortive effect, can also strengthen and can also improve female rabbit resistance against diseases, promotes lactogenic, the survival rate of the young rabbit of promotion.Prescription effectively avoided using the chemical classes drug side effect large, residual shortcoming is arranged, improved powder spice effect, absorption difference and the large problem of use amount, can reach the purpose of rapid onset.
Bred first 10 days and the success of female rabbit started to add this Chinese prescription to young rabbit wean after conceived on the 15th day, every female rabbit is used 0.5 gram every day.
Advantage of the present invention: the Radix Astragali, Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI in side; Fructus Lycii, Radix Salviae Miltiorrhizae, Herba Epimedii, the Cortex Eucommiae are reinforced the kidney and are protected the liver with fetus nourishing unit; Because rabbit body temperature is higher, heat radiation is not enough, adds the Radix Scutellariae heat clearing and tranquillizing again, with the Rhizoma Atractylodis Macrocephalae, with using, strengthens antiabortive effect; The Radix Glycyrrhizae QI invigorating and in, coordinating the actions of various ingredients in a prescription, above 8 the flavor Chinese medicines bring out the best in each other, treating both the principal and secondary aspects of a disease, not only can strengthen invigorating the spleen and benefiting QI, nourishing blood and preventing abortion, can also improve female rabbit resistance against diseases, promotes female rabbit galactopoiesis, the raising young rabbit survival rate.Simultaneously, this prescription has the characteristics such as source is easy to get, cost is lower, easy to use, effect is remarkable.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is described in detail.
Embodiment 1
According to the Radix Astragali 15 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, Radix Scutellariae 15 weight portions, Fructus Lycii 12.5 weight portions, Radix Salviae Miltiorrhizae 12.5 weight portions, Herba Epimedii 10 weight portions, the Cortex Eucommiae 10 weight portions, the Radix Glycyrrhizae 10 weight portions Chinese herbal medicine of weighing; For example, get Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 15g, Radix Scutellariae 15g, Fructus Lycii 12.5g, Radix Salviae Miltiorrhizae 12.5g, Herba Epimedii 10g, Cortex Eucommiae 10g, Radix Glycyrrhizae 10g, carry out the micropowder pulverization and become the 45 big or small micropowders in μ m left and right, mix the pack sealing standby, obtain the Chinese prescription that the present invention improves female rabbit propagation production performance.
This product is (1) fineness: 95% should be by No. 9 sieves.(2) body colour: be the brown color powder; Gas delicate fragrance, mildly bitter flavor.Dry, pine is dredged, mix homogeneously, and color and luster is consistent.(3) storage: general powder is answered airtight storage, contains the powder that volatile oil or moisture absorption are strong and answers sealed type storage.(4) uniformity: get appropriate powder, be placed on glossy paper and tile approximately 5 square centimeters, its surface is flattened, observe at bright place, present uniform color and luster, without decorative pattern and mottle.(5) moisture inspection: be no more than 9%.
Embodiment 2
48 of the female rabbits of healthy adult, 2.5 kilograms of left and right of body weight, be divided into 4 groups at random, every group of 3 repetitions, each repeats 4.Wherein all groups are used same basic daily ration, control group fed basal diet; The loose fowl of common Chinese is freely organized and (contains the Radix Astragali, Radix Codonopsis, Radix Rehmanniae Preparata, smashing fineness 60 mesh sieves) every rabbit feed every day 1.2 grams, chemical medicine stress element organize (containing vitamin A. D. E) every rabbit feed every day 0.2 gram, certainly intend the Chinese prescription group, bred first 10 days and the success of female rabbit started to add to young rabbit wean after conceived on the 15th day, every rabbit 0.5 gram of feeding every day.Preliminary trial period, enter experimental period after finishing, and experimental period is 65d, is set as the rear 25d wean of young rabbit birth, and female rabbit also freely drinks water and searches for food.After off-test, obtain following result:
(1) female rabbit breeding, farrowing situation
Have table 1 to find out, the matched group breeding rate is minimum, and the other drug group is higher than matched group.Litter size relatively, is intended the Chinese prescription group maximum certainly, and matched group is minimum.
Table 1 fowl is smooth, stress element, certainly intend the impact of prescription on female rabbit breeding rate, litter size
(2) impact of each medicine on female rabbit lactation amount
As shown in Table 2, each is organized 14d and reaches the lactogenic peak, then is and downward trend, and it is not remarkable that 1-21d respectively organizes difference, and during 25d, certainly intends Chinese drug-treated group and matched group, fowl and freely organize difference extremely significantly (P<0.01), improves 146.83%, 68.1%.Chinese drug-treated group group lactation amount is all higher in each stage from intending.
Table 2 fowl is smooth, stress element, certainly intend the impact of prescription Chinese medicine on female rabbit lactation amount
Annotate: different capitalization difference extremely significantly (P<0.01) in same column, different lower case significant differences (P<0.05), not marking-up is female or same letter difference not significantly (P>0.05) arranged; Lower same.
(3) fowl smooth, stress element, certainly intend the impact of prescription Chinese medicine on young rabbit body weight, survival rate
As shown in Table 3, during 1d, matched group and fowl are freely organized difference extremely significantly (P<0.01), and stress element group significant difference (P<0.05); From intending Chinese drug-treated group and matched group significant difference (P<0.05), improve 11.82%.During 21d, matched group and fowl are intended Chinese drug-treated group significant difference (P<0.05) freely, certainly, certainly intend Chinese drug-treated group and improve 4.86% than matched group; During 25d, matched group and fowl are intended Chinese drug-treated group difference extremely significantly (P<0.01) freely, certainly, certainly intend Chinese drug-treated group and improve 10.44% than matched group, certainly intend Chinese drug-treated group and fowl smooth, stress element organize also difference extremely remarkable (P<0.01).The survival rate comparison, matched group is intended Chinese drug-treated group significant difference (P<0.05) with oneself, certainly intends Chinese drug-treated group and improves than matched group, 67.30%.
Table 3 fowl is smooth, stress element, certainly intend the impact of prescription Chinese medicine on young rabbit body weight and survival rate
(4) 2.3 fowl are smooth, stress element, certainly intend the impact of prescription Chinese medicine on female rabbit body weight change
As shown in Table 4, the antenatal difference not remarkable (P>0.05) of respectively organizing.Puerperal, certainly intend Chinese drug-treated group rate of body weight gain and other 3 groups of differences extremely significantly (P<0.01), certainly intend Chinese drug-treated group and improve 41.67 times than matched group; During wean, also significant difference (P<0.05), certainly intend Chinese drug-treated group and improve 1.93 times than matched group.
Table 4 fowl is smooth, stress element, certainly intend the impact of prescription Chinese medicine on female rabbit body weight
(5) fowl smooth, stress element, certainly intend the impact of prescription Chinese medicine on female rabbit biochemical indicator
As shown in Table 5, certainly intend Chinese drug-treated group glutamic oxaloacetic transaminase, GOT and matched group significant difference (P<0.05), certainly intend Chinese drug-treated group and reduce by 13.14% than matched group; It is not remarkable that glutamate pyruvate transaminase is respectively organized difference, stress organize, certainly intend Chinese drug-treated group T-CHOL and matched group significant difference (P<0.05) by element, from intending Chinese drug-treated group, than matched group, reduce by 52.56%, triglyceride is significant difference (P<0.05) more also, certainly intends Chinese drug-treated group and reduces by 21.79% than matched group.
Table 5 fowl is smooth, stress element, certainly intend the impact of prescription Chinese medicine on female rabbit biochemical indicator
With matched group, relatively add from intending lactation amount that the prescription Chinese medicine utmost point significantly improved female rabbit, puerperal rate of body weight gain and young rabbit birth weight, weaning weight (P<0.01), significantly improve the survival rate (P<0.05) of young rabbit, and significantly reduced the content of glutamic oxaloacetic transaminase, GOT, T-CHOL, triglyceride (P<0.05) in serum.From plan prescription Chinese medicine, can significantly improve the propagation production performance of female rabbit.
Should be understood that, for those of ordinary skills, can be improved according to the above description or conversion, and all these improve and conversion all should belong to the protection domain of claims of the present invention.
Claims (2)
1. a Chinese prescription that improves female rabbit propagation production performance, adopt following Chinese crude drug preparation: the Radix Astragali 15 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, Radix Scutellariae 15 weight portions, Fructus Lycii 12.5 weight portions, Radix Salviae Miltiorrhizae 12.5 weight portions, Herba Epimedii 10 weight portions, the Cortex Eucommiae 10 weight portions, Radix Glycyrrhizae 10 weight portions.Above-mentioned Chinese crude drug is dried respectively, then use pulverizing mill to pulverize, after crossing 200 sieves, according to aforementioned proportion, mix.
2. preparation that improves the Chinese prescription of female rabbit propagation production performance: get respectively the Radix Astragali 15 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, Radix Scutellariae 15 weight portions, Fructus Lycii 12.5 weight portions, Radix Salviae Miltiorrhizae 12.5 weight portions, Herba Epimedii 10 weight portions, the Cortex Eucommiae 10 weight portions, Radix Glycyrrhizae 10 weight portions and dry, then carry out after thick level is pulverized re-using micro-powder crusher and carry out micronizing, after crossing 300 sieves, reach 45 μ m left and right, according to aforementioned proportion, mix.
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Cited By (7)
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| CN103947880A (en) * | 2014-04-28 | 2014-07-30 | 江苏省农业科学院 | Functional compound premix for long hair rabbits |
| CN104082553A (en) * | 2014-06-10 | 2014-10-08 | 芜湖县绿色草原兔业养殖专业合作社 | Rabbit feed used in gestation period and preparation method thereof |
| CN104887821A (en) * | 2015-06-25 | 2015-09-09 | 李春燕 | Medicine for increasing rabbit reproduction rate |
| CN105941955A (en) * | 2016-06-21 | 2016-09-21 | 山东新希望六和集团有限公司 | Feed additive for female rabbit raising |
| CN108522853A (en) * | 2018-07-09 | 2018-09-14 | 山东龙昌动物保健品有限公司 | Application of the eucommia leaf extract in preparing the feed addictive for improving female rabbit reproductive performance |
| CN111053807A (en) * | 2020-02-11 | 2020-04-24 | 内蒙古农业大学 | Traditional Chinese medicine preparation for preventing and treating dog threatened abortion and preparation method thereof |
| CN112293575A (en) * | 2020-10-26 | 2021-02-02 | 辽宁农业职业技术学院 | Compound feed additive for improving reproductive performance of cashmere goat ewes and preparation method thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103947880A (en) * | 2014-04-28 | 2014-07-30 | 江苏省农业科学院 | Functional compound premix for long hair rabbits |
| CN103947880B (en) * | 2014-04-28 | 2015-12-09 | 江苏省农业科学院 | Functional hair rabbit compound premix |
| CN104082553A (en) * | 2014-06-10 | 2014-10-08 | 芜湖县绿色草原兔业养殖专业合作社 | Rabbit feed used in gestation period and preparation method thereof |
| CN104887821A (en) * | 2015-06-25 | 2015-09-09 | 李春燕 | Medicine for increasing rabbit reproduction rate |
| CN105941955A (en) * | 2016-06-21 | 2016-09-21 | 山东新希望六和集团有限公司 | Feed additive for female rabbit raising |
| CN108522853A (en) * | 2018-07-09 | 2018-09-14 | 山东龙昌动物保健品有限公司 | Application of the eucommia leaf extract in preparing the feed addictive for improving female rabbit reproductive performance |
| CN111053807A (en) * | 2020-02-11 | 2020-04-24 | 内蒙古农业大学 | Traditional Chinese medicine preparation for preventing and treating dog threatened abortion and preparation method thereof |
| CN112293575A (en) * | 2020-10-26 | 2021-02-02 | 辽宁农业职业技术学院 | Compound feed additive for improving reproductive performance of cashmere goat ewes and preparation method thereof |
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