CN113662103A - Composition for improving reproductive performance of female rabbits and application and method thereof - Google Patents
Composition for improving reproductive performance of female rabbits and application and method thereof Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/50—Feeding-stuffs specially adapted for particular animals for rodents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/02—Breeding vertebrates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Environmental Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Birds (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Physiology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a composition for improving reproductive performance of female rabbits and application and a method thereof, and firstly provides a composition for improving reproductive performance of female rabbits, which comprises the following components: methionine iron, chlorogenic acid and angelica; the mass ratio of the methionine iron, the chlorogenic acid and the angelica is 60-100:150-250: 250-350. The invention also discloses application of the composition for improving the reproductive performance of the female rabbits in female rabbit reproduction. And a method for improving the reproductive performance of female rabbits, which comprises the following steps: the composition for improving the reproductive performance of the female rabbits is added to the female rabbits for more than 10-14 days, and the addition amount is 400-700g/1000 kg. The composition of methionine iron, chlorogenic acid and angelica is added into the daily ration of the female rabbit, so that the reproductive performance of the female rabbit is improved, the hemoglobin content in the blood of the female rabbit is increased, and the anemia condition of the female rabbit is improved.
Description
Technical Field
The invention relates to the technical field of female rabbit breeding improvement, and particularly relates to a composition for improving female rabbit breeding performance, and application and a method thereof.
Background
At present, the rabbit breeding industry enters a large-scale and intensive breeding mode, particularly, a 42-day or 49-day mode is adopted in a breeding mode, and female rabbits can be bred in a high-strength breeding state. The breeding production mode puts higher requirements on the body condition of the breeding female rabbits, if the body condition of the breeding female rabbits is weaker, the breeding performance of the breeding female rabbits is reduced, the utilization period of the breeding female rabbits is shortened, and the breeding economic benefit is damaged.
Iron is a major mineral element involved in enzymes involved in oxygen transport and metabolism. Iron deficiency can lead to a blockage of hemoglobin production and anemia in the animal.
Blood transportation oxygen and nutrients, which are information conductors, participate in the regulation of body fluids; hormones (e.g., estradiol, follitropin, prolactin, growth hormone, etc.), enzymes, vitamins, etc., are transported to the appropriate target organs of the animal by means of the blood. Once the animal has anemia, the above physiological functions are affected, which means that reproduction, production performance is reduced, and even diseases occur.
Blood is an indispensable component in animals and human bodies, and plays an extremely important buffering role in balancing contradictions between organisms and environments. The hemoglobin content in blood is related to the body resistance and can change along with the change of the health and physiological state of the animal body. Higher hemoglobin concentration is beneficial to oxygen transfer, immune function improvement and metabolism capability enhancement. Hemoglobin is the most predominant carrier for oxygen and carbon dioxide in the body.
On people and animals, the hemoglobin content in blood is a reliable index for evaluating the anemia condition of an organism, and the method has the characteristics of easiness in determination and the like, can effectively know the anemia condition of the animals by detecting the hemoglobin content in the blood of the animals, and master the healthy physiological condition of the animals. In pigs, when the hemoglobin concentration value is lower than 90g/L, anemia can be judged, the hemoglobin concentration value is 90-110g/L, subclinical anemia can be judged, and the optimal hemoglobin concentration value of the organism is higher than 110 g/L.
Under normal conditions, the value of the rabbit hemoglobin concentration is 100-150 g/L. According to investigation, in the culture production, the hemoglobin content of the multiparous female rabbit is about 90g/L, the multiparous female rabbit is in an anemia state, and the reproductive performance is reduced. Therefore, the problem of anemia of the multiparous female rabbits is solved through a scientific method, the reproductive performance of the multiparous female rabbits is improved, and the method has very important value and significance.
In the animal body, 65% of iron exists in blood, and 70% -75% of iron exists in the form of hemoprotein, mainly including hemoglobin, myoglobin and partial enzyme. It has been found in a number of studies that iron in the feed is released by the action of gastric acid and pepsin and reduced to ferrous iron, the site of absorption of which by the animal is mainly in the duodenum. The iron in the heme compound need not be released from the conjugate, can be directly absorbed by intestinal cells in the form of porphyrin iron, and the ferrous organic compounds are more easily absorbed in the intestinal tract.
Iron is one of the essential trace elements for animals to maintain life and grow, and is widely involved in various life activities in vivo. Exogenous iron is added into the feed in the livestock production, and mainly inorganic iron is used as the main material. However, the inorganic iron has low absorption and utilization rate, so trace element resource waste and environmental pollution are often caused in actual production, and meanwhile, the inorganic iron is easy to cause oxidative stress damage to organisms in the absorption process to influence the production performance of animals.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides a composition for improving the reproductive performance of female rabbits and application and a method thereof.
In order to achieve the purpose, the technical scheme adopted by the invention for solving the technical problems is as follows: the composition for improving the reproductive performance of the female rabbits comprises the following components: methionine iron, chlorogenic acid and angelica; the mass ratio of the methionine iron, the chlorogenic acid and the angelica is 60-100:150-250: 250-350.
Further, the composition for improving the reproductive performance of the female rabbits is characterized in that the mass ratio of the methionine iron to the chlorogenic acid to the angelica is 80:200: 300.
Furthermore, the mesh number of the angelica is 250-350 meshes.
The composition for improving the reproductive performance of the female rabbits is applied to the reproduction of the female rabbits.
The composition for improving the reproductive performance of the female rabbits is applied to daily ration for feeding the female rabbits.
A method for improving reproductive performance of female rabbits comprises the following steps: the composition for improving the reproductive performance of the female rabbits is added to the female rabbits for more than 10-14 days, and the addition amount is 400-700g/1000 kg.
Further, the amount of the additive was 580g/1000 kg.
The iron methionine is an amino acid chelated iron, and iron ions are combined with amino acids in a coordination bond form to form a chelate with a cyclic structure; compared with inorganic iron salts and simple organic acid iron salts, the amino acid chelated iron has the advantages of high bioavailability, good chemical stability, environmental protection and the like.
Chlorogenic acid is an important bioactive substance, and has antibacterial, antiviral, liver protecting, gallbladder function promoting, antitumor, blood pressure lowering, blood lipid reducing, free radical scavenging, and central nervous system exciting effects. Chlorogenic acid is an effective phenolic antioxidant, and has higher antioxidant capacity than caffeic acid, tocopherol (vitamin E), ascorbic acid (vitamin C), etc. Chlorogenic acid contains a certain amount of R-OH groups, can form hydrogen radicals with antioxidant effect to eliminate activity of DPPH radicals, hydroxyl radicals and superoxide anions, and inhibit oxidation of low density lipoprotein, thereby protecting tissue from damage due to oxidation. Chlorogenic acid has important effects in scavenging free radicals in vivo, and maintaining normal structure and function of body cells. The addition of chlorogenic acid in the feed has positive effects on animal physiological health, and simultaneously the antioxidant effect of the feed can effectively prevent Fe in animal intestinal tract2+To Fe3+The oxidation of (2) is beneficial to the absorption of iron.
Radix Angelicae sinensis has effects of regulating blood and qi, replenishing blood, stopping bleeding, and regulating menstruation. Modern medical research shows that the angelica can effectively improve the anti-hypoxia capability of an organism and increase the blood flow of the periphery of the organism, thereby reducing the blockage of blood vessels of the organism and improving the peripheral microcirculation. Meanwhile, the angelica has certain hematopoietic function and can promote the organism to generate red blood cells and hemoglobin, the main bioactive substance of the angelica is angelica polysaccharide, and the other biological effective components of the angelica, such as ferulic acid, decocted acid, gland claim and the like, can improve the hematopoietic function of the organism to a certain degree. After the Chinese angelica is subjected to superfine grinding treatment, the cell wall is broken, the absorption of effective components is facilitated, and the pharmacological effect of the Chinese angelica is exerted.
In summary, the invention has the following advantages:
1. compared with inorganic iron, the amino acid chelate iron has the advantages of high bioavailability, good chemical stability and the like, and the iron methionine added into the feed can effectively meet the requirement of high-strength breeding female rabbits on trace element iron and effectively solve the problem of iron-deficiency anemia, wherein the biological effect of the iron methionine is particularly obvious. Only Fe can be absorbed in intestinal tract of rabbit2+. Chlorogenic acid is an important bioactive substance, is effective in resisting oxidation, and can effectively prevent Fe in animal intestinal tract2+To Fe3+Is beneficial to Fe in methionine iron2+The chlorogenic acid also has the effects of eliminating in-vivo free radicals and maintaining the normal structure and function of somatic cells, and the addition of the chlorogenic acid has positive effects on the physiological health of the rabbits. The angelica has the effects of regulating blood and qi, enriching blood and the like, and can effectively improve the blood flow at the periphery of the organism, thereby reducing the blockage of blood vessels of the organism, improving the microcirculation at the periphery and promoting the organism to generate red blood cells and hemoglobin; the increase of hemoglobin can increase Fe in methionine iron absorbed by intestinal tract2+The anemia is more fully utilized, and the problem of anemia is better solved; the improvement of the peripheral blood flow of the body is more beneficial to the transportation of nutrient substances and the reproductive physiology of animals.
2. The application of the methionine iron effectively solves the problem of bioavailability of iron by animals; chlorogenic acid and methionine iron are used in combination to prevent Fe2+To Fe3+Oxidation of (2) to ensure Fe in methionine iron2+The absorption of the nutrient substances can ensure that the organism is healthier and is beneficial to the digestion and absorption of the nutrient substances; radix Angelicae sinensis promotes hemoglobin production, and is suitable for high Fe2+The absorption capacity can fully and effectively solve the problem of anemia, the improvement of the peripheral blood flow of the organism is more beneficial to the transportation of nutrient substances, the absorption and utilization of the nutrient substances by the breeding female rabbits are ensured, and the good body condition of the breeding female rabbits is maintained. Methionine iron is transferred to the fetus through the placenta, and the absorption of the fetus to methionine is increased while the iron is absorbed by the fetus, so that the nutrition loss of the female rabbit is prevented, and the normal body condition of the bred female rabbit is maintained.
3. The composition of the invention is added into the daily ration of female rabbits, so that the hemoglobin content of the female rabbits can be maintained above 100g/L, and the problem of anemia of the breeding female rabbits (the hemoglobin content is above 100 g/L) can be effectively solved; the oestrus rate, the mating rate and the farrowing rate of the breeding female rabbits can be effectively improved; can obviously improve the individual weight of the newborn rabbit at birth, the litter weight, the individual weight of 21-day-old rabbits, the litter weight of 21-day-old rabbits, the individual weight of 35-day-old weaning rabbits and the litter weight of 35-day-old weaning rabbits. Therefore, the composition and the method for improving the reproductive performance of the female rabbits can obviously improve the reproductive production performance of the female rabbits, and have good academic value and wide market application prospect.
Detailed Description
Example 1
A composition for improving reproductive performance of female rabbits comprises the following components: methionine iron, chlorogenic acid and angelica; the mass ratio of the methionine iron to the chlorogenic acid to the angelica is 60:150: 250. The mesh number of Chinese angelica is 250 meshes.
The application of the composition for improving the reproductive performance of the female rabbits in the reproduction of the female rabbits comprises the following steps: feeding the composition added with the composition for improving the reproductive performance of the female rabbits for more than 10 days, wherein the addition amount is 400g/1000 kg.
Example 2
A composition for improving reproductive performance of female rabbits comprises the following components: methionine iron, chlorogenic acid and angelica; the mass ratio of the methionine iron to the chlorogenic acid to the angelica is 80:200: 300. The mesh number of Chinese angelica is 300 meshes.
The application of the composition for improving the reproductive performance of the female rabbits in the reproduction of the female rabbits comprises the following steps: feeding the composition added with the composition for improving the reproductive performance of the female rabbits for more than 12 days at the addition of 580g/1000 kg.
Example 3
A composition for improving reproductive performance of female rabbits comprises the following components: methionine iron, chlorogenic acid and angelica; the mass ratio of the methionine iron, the chlorogenic acid and the angelica is 100:250: 350. The number of meshes of Dang Gui is 350 meshes.
The application of the composition for improving the reproductive performance of the female rabbits in the reproduction of the female rabbits comprises the following steps: feeding the composition added with the composition for improving the reproductive performance of the female rabbits for more than 14 days, wherein the addition amount is 700g/1000 kg.
Experimental example 1
Selecting 120 healthy and disease-free new zealand female rabbits with the age of 180-day plus 200 days, randomly dividing the rabbits into 4 groups, feeding the rabbits in a single cage in each group with 30 animals in each group, feeding the rabbits in a single cage with 6 animals in each group, feeding the rabbits in a test 1 group, a test 2 group, a test 3 group and a control group (the test design is shown in table 1) in each group with 5 animals in each group, feeding corresponding daily rations 14 days before the first breeding cycle in the test starting time, adopting a 49-day breeding mode (18-day breeding after production and natural mating), weaning the rabbits in 35 days, wherein the test period is three continuous breeding cycles, and ending the test when the rabbits in the third breeding cycle are 35 days in the weaning time. The composition and nutritional level of the diet are shown in table 2. All test animals were housed in the same rabbit hutch and were fed freely and had automatic drinking. Other feeding management and immunization programs were performed as normal procedures.
1000kg of mixture consists of 80g of methionine iron, 150g of chlorogenic acid and 250g of angelica, wherein the angelica is sieved by a 300-mesh sieve and prepared into the ultrafine powder.
TABLE 1 design of the experiments
TABLE 2 basic diet composition and Nutrition level (air-dried basis)
Note: 1) the premix can provide per kilogram of complete feed: 120Mg of Cu, 90Mg of Zn, 30Mg of Mn, 150Mg of Mg, 4000IU of VA, 31000 IU of VD, 50Mg of VE and 1Mg of choline.
Note 2) digestion energy is calculated, the remainder are found.
And (3) carrying out reproductive performance measurement on the test animal, and simultaneously measuring the hemoglobin content in blood at different time points:
the determination of the reproductive performance index shows that: oestrus rate, mating rate, farrowing rate, litter size born alive, litter weight born alive, individual weight born alive, litter size 21 days old (representing lactation), individual weight 21 days old, litter size 35 days old, individual weight 35 days old per breeding cycle.
And (3) hemoglobin content determination: on the test start day, the first breeding period, the second breeding period, the third breeding period and the test end day (corresponding to time points 1, 2, 3, 4 and 5), 5ml of blood is collected from the ear artery, and the blood is measured by a full-automatic blood cell analyzer.
Statistical analysis: after the test data are processed by Excel2013 software, SPSS16.0 statistical software is adopted for variance analysis, multiple comparisons are carried out by a Duncan method, the result is expressed by 'mean value plus or minus standard error', and P <0.05 is used as a difference significance judgment standard.
The above-mentioned reproductive performance and hemoglobin measurement results are shown in tables 3 and 4, respectively.
TABLE 3 Effect of reproductive Performance in three reproductive cycles
| Group of | Estrus rate/%) | Proportion of the whole | Farrowing rate/%) |
| Test 1 group | 77.78a | 72.22a | 70.00a |
| Test 2 groups | 86.67b | 84.44b | 83.33b |
| Test 3 groups | 90.00b | 86.67b | 86.67b |
| Control group | 72.22a | 67.78a | 66.67a |
Note: in Table 3, the data in the same column are marked with different lower case letters to indicate significant difference (P <0.05), and the same or no letters to indicate insignificant difference (P > 0.05).
As can be seen from table 3, in the aspect of oestrus rate, 77.78%, 86.67%, 90.00%, and 72.22% are respectively observed in the test groups 1, 2, and 3 and the control group, the test groups 2 and 3 are significantly higher than the test group 1 and the control group (P <0.05), the difference between the test group 1 and the control group is not significant (P > 0.05), and the difference between the test group 2 and the test group 3 is not significant (P > 0.05); in the aspect of the matching rate, the test 1, the test 2, the test 3 and the control group are 72.22%, 84.44%, 86.67% and 67.78% respectively, the test 2 and the test 3 are obviously higher than the test 1 and the control group (P <0.05), the difference between the test 1 and the control group is not significant (P > 0.05), and the difference between the test 2 and the test 3 is not significant (P > 0.05); in the aspect of farrowing rate, 70.00%, 83.33%, 86.67% and 66.67% are respectively used for the test groups 1, 2 and 3 and the control group, the test groups 2 and 3 are significantly higher than the test group 1 and the control group (P <0.05), the difference between the test group 1 and the control group is not significant (P > 0.05), and the difference between the test group 2 and the test group 3 is not significant (P > 0.05).
TABLE 4 Effect of different early mating months ages on the Productivity of three reproductive cycle young rabbits
| Item | Test 1 group | Test 2 groups | Test 3 groups | Control group |
| Litter size/unit | 8.11±1.19 | 8.24±1.25 | 8.42±1.38 | 7.94±1.07 |
| Number born alive/litter | 7.95±1.08 | 8.17±1.19 | 8.34±1.24 | 7.77±0.98 |
| Weight of newborn nest/g | 437.24±47.77a | 466.12±46.21b | 517.12±51.02b | 419.54±42.35a |
| Weight of newborn individual/g | 54.95±2.46a | 57.21±2.62b | 61.98±3.38c | 53.98±2.55a |
| 21-day-old live litter/stick | 7.58±0.84 | 7.91±0.87 | 8.11±1.12 | 7.41±0.78 |
| 21 day old litter weight/g | 2412.57±259.44a | 2573.92±264.74b | 2702.91±285.11b | 2335.21±238.98a |
| Individual weight/g for 21-day-old | 317.82±22.17a | 325.32±22.94b | 333.21±25.47b | 315.14±21.67a |
| 35 days old live larva/larva | 7.24±0.85 | 7.65±0.99 | 7.84±1.02 | 7.15±0.76 |
| 35 day old litter weight/g | 5262.17±531.18a | 5848.92±596.87b | 6103.12±621.46b | 5120.12±521.27a |
| 35 age in days individual weight/g | 726.73±21.11a | 764.51±25.04b | 778.38±27.04b | 720.19±20.31a |
Note: in Table 4, the data in the same row are marked with different lower case letters to indicate that the difference is significant (P <0.05), and the same or no letters to indicate that the difference is not significant (P > 0.05).
As can be seen from Table 4, the litter sizes of the test groups 1, 2 and 3 and the control group are 8.11, 8.24, 8.42 and 7.94 respectively, the test groups 1, 2 and 3 are higher than the control group, and the difference of 0 among the four groups is not significant (P is more than 0.05); in terms of number of born alive offspring, the test groups 1, 2 and 3 and the control group are respectively 7.95, 8.17, 8.34 and 7.77, the test groups 1, 2 and 3 are higher than the control group, and the difference among the four groups is not significant (P is more than 0.05). The weights of the primary litter of the test group 1, the test group 2, the test group 3 and the control group are 437.24g, 466.12g, 517.12g and 419.54g respectively, the weights of the test group 2 and the control group 3 are obviously higher than those of the test group 1 and the control group (P is less than 0.05), and the difference between the test group 2 and the control group 3 is not significant (P is more than 0.05); the initial individual weights of the test 1, the test 2, the test 3 and the control group are respectively 54.95g, 57.21g, 61.98g and 53.98g, the test 3 group is obviously higher than other test groups (P is less than 0.05), and the control group is obviously lower than the test 2 and the control group (P is less than 0.05). The number of live litter of 21-day-old in the test 1, 2, 3 and control groups is respectively 7.58, 7.91, 8.11 and 7.41, the difference among the groups is not significant (P is more than 0.05), the weight of 21-day-old litter of the test 1, 2, 3 and control groups is respectively 2412.57g, 2573.92g, 2702.91g and 2335.21g, the difference among the test 2 and 3 groups is significantly higher than that of the test 1 group and that of the control group (P is less than 0.05), and the difference among the test 2 and 3 groups is not significant (P is more than 0.05); the individual weights of the test 1 group, the test 2 group, the test 3 group and the control group at 21 days are 317.82g, 325.32g, 333.21g and 315.14g respectively, the weight of the test 2 group and the control group is obviously higher than that of the test 1 group and that of the control group (P is less than 0.05), and the difference between the test 2 group and the control group is not significant (P is more than 0.05). The number of 35-day-old live larvae in the test groups 1, 2 and 3 and the control group is respectively 7.24g, 7.65g, 7.84g and 7.15g, and the difference among the groups is not significant (P is more than 0.05); the nest weights of the test 1 group, the test 2 group, the test 3 group and the control group are 5262.17g, 5848.92g, 6103.12g and 5120.12g respectively, the test 2 group and the test 3 group are obviously higher than those of the test 1 group and the control group (P is less than 0.05), and the difference between the test 2 group and the control group is not significant (P is more than 0.05); the individual weights of the test 1, the test 2, the test 3 and the control group at 35 days are 726.73g, 764.51g, 778.38g and 720.19g respectively, the weights of the test 2 and the control group are obviously higher than those of the test 1 and the control group (P is less than 0.05), and the difference between the test 2 and the control group is not significant (P is more than 0.05).
TABLE 5 mean hemoglobin content Change in female rabbits
Note: in table 5, the data in the same column are marked with different lower case letters to show significant difference (P > 0.05), and the same or no letter to show insignificant difference (P > 0.05); the data from the same row indicated significant differences (P > 0.05) by number, and no or the same number indicated insignificant differences (P > 0.05).
As can be seen from Table 5, at time 1 (day of start of the experiment), the hemoglobin contents of the test groups 1, 2 and 3 and the control group were 88.38g/L, 91.12g/L, 90.27g/L and 89.03g/L, respectively, and the difference between the groups was not significant (P > 0.05); at the time point 2 (the mating day of the first breeding cycle), the hemoglobin contents of the test group 1, the test group 2, the test group 3 and the control group are 98.37g/L, 105.38g/L, 112.34g/L and 95.67g/L respectively, the hemoglobin contents of the test group 2 and the control group 3 are obviously higher than those of the test group 1 and the control group (P is less than 0.05), and the difference between the test group 2 and the control group 3 is not significant (P is more than 0.05); at time point 3 (second breeding cycle mating day), the hemoglobin contents of the test 1, the test 2, the test 3 and the control group are respectively 96.82g/L, 103.54g/L, 109.63g/L and 88.47g/L, the control group is obviously lower than the test 1, the test 2 and the test 3 (P is less than 0.05), the test 2 and the test 3 are obviously higher than the test 1 (P is less than 0.05), and the difference between the test 2 and the test 3 is not obvious (P is more than 0.05); at time point 4 (third breeding cycle mating day), the hemoglobin contents of the test 1, the test 2, the test 3 and the control group are 94.31g/L, 102.82g/L, 106.37g/L and 85.62g/L respectively, the hemoglobin contents of the control group are obviously lower than those of the test 1, the test 2 and the test 3 (P is less than 0.05), the hemoglobin contents of the test 2 and the control group are obviously higher than those of the test 1 (P is less than 0.05), and the difference between the test 2 and the test 3 is not significant (P is more than 0.05); at time point 5 (test end date), the hemoglobin contents of the test groups 1, 2 and 3 and the control group are 93.98g/L, 102.01g/L, 105.98g/L and 86.37g/L respectively, the hemoglobin contents of the test groups 2 and 3 are obviously higher than those of the test group 1 and the control group (P is less than 0.05), the difference between the test group 1 and the control group is not significant (P is more than 0.05), and the difference between the test group 2 and the control group 3 is not significant (P is more than 0.05).
Test 1, time points 1, 2, 3, 4, 5, hemoglobin contents of 88.38g/L, 98.37g/L, 96.82g/L, 94.31g/L, 93.98g/L, respectively, were significantly higher at time point 2 and time point 3 than at other time points (P < 0.05); test 2, time points 1, 2, 3, 4, 5, hemoglobin contents of 91.12g/L, 105.38g/L, 103.54g/L, 102.82g/L, 102.01g/L, respectively, time point 1, hemoglobin content significantly lower than other time points (P < 0.05); test 3, time points 1, 2, 3, 4, 5, hemoglobin contents of 90.27g/L, 112.34g/L, 109.63g/L, 106.37g/L, 105.98g/L, respectively, were significantly lower at time point 1 than at other time points (P < 0.05); the control group, time points 1, 2, 3, 4, 5, had a hemoglobin content of 89.03g/L, 95.67g/L, 88.47g/L, 85.62g/L, 86.37g/L, respectively, with the highest hemoglobin content at time point 2, but the differences between the time points were not significant (P > 0.05).
In conclusion, a certain amount of methionine iron, chlorogenic acid and angelica sinensis compound is added into the female rabbit feed, so that the hemoglobin content of the female rabbits with high propagation can be remarkably increased and maintained at more than 100g/L, and anemia symptoms of the female rabbits with high propagation can be effectively prevented and treated. The content of hemoglobin in the female rabbit is increased, the immunity of the body is improved, the health and physiological state of the body of the female rabbit is actively improved, the metabolic capability is enhanced, and the oestrus rate and the mating rate are improved. The improvement of the body health of the female rabbit can be reflected by the production performance of the newborn rabbit, the female rabbit can transfer methionine iron to a fetus through a placenta, the absorption of amino acid is increased while the iron is absorbed by the fetus, and the individual weight of the birth of the female rabbit is obviously improved; the litter weight of 21 days represents the lactation capacity of the female rabbit, and the research result shows that the addition of a certain amount of iron methionine, chlorogenic acid and angelica can obviously improve the lactation capacity of the female rabbit and can improve the weaned individual weight and the litter weight of the young rabbit.
While the present invention has been described in detail with reference to the specific embodiments thereof, it should not be construed as limited by the scope of the present patent. Various modifications and changes may be made by those skilled in the art without inventive step within the scope of the appended claims.
Claims (7)
1. The composition for improving the reproductive performance of female rabbits is characterized by comprising the following components: methionine iron, chlorogenic acid and angelica; the mass ratio of the methionine iron, the chlorogenic acid and the angelica is 60-100:150-250: 250-350.
2. The composition for improving reproductive performance of a female rabbit according to claim 1, wherein the mass ratio of methionine iron, chlorogenic acid and angelica sinensis is 80:200: 300.
3. The composition for improving reproductive performance of a female rabbit as claimed in claim 1, wherein the mesh number of said Angelica sinensis is 250-350 mesh.
4. Use of a composition according to any one of claims 1 to 3 for increasing reproductive performance in female rabbits.
5. Use of a composition according to any one of claims 1 to 3 for increasing reproductive performance of female rabbits in a daily ration for female rabbits.
6. A method for improving reproductive performance of female rabbits is characterized by comprising the following steps: feeding the composition for improving the reproductive performance of the female rabbits, which is added according to any one of claims 1 to 3, for more than 10-14 days, wherein the addition amount is 400-700g/1000 kg.
7. The method for improving reproductive performance of female rabbits according to claim 1, wherein the addition amount is 580g/1000 kg.
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