CN106214532A - There is compositions of control oil bacteriostasis efficacy and preparation method thereof - Google Patents
There is compositions of control oil bacteriostasis efficacy and preparation method thereof Download PDFInfo
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Abstract
nullThe present invention relates to a kind of compositions with control oil bacteriostasis efficacy，Its formula includes each component of following mass percent: PEG 20 methyl sesquistearate 0.8%～3.0%、Isooctadecanol isostearate 1.0%～5.0%、Methyl sesquistearate 1.0%～2.0%、Isononyl isononanoate 2.0%～6.0%、Glycerol 2.0%～8.0%、Hyaluronate sodium 0.02%～0.1%、Thickening agent 0.08%～0.3%、Octyl group succinic acid aluminum starch 0.5%～3.0%、Propylene glycol 0.8%～5.0%、Anti-sensitizer 0.1%～0.3%、Biopol β 2.0%～5.0%、Glucosan 1.0%～3.0%、Radix Hamamelidis Mollis extracting solution 1.0%～5.0%、Surplus is deionized water.The present invention provides the compositions with control oil bacteriostasis efficacy can persistently control skin oil and fat secretion, the unnecessary oils and fats of skin secretion can be absorbed simultaneously, have good antibacterial bacteriostatic effect, it is not necessary to add preservative, it is a high safety, product without any side effects.
Description
Technical field
The invention belongs to cosmetic field, be specifically related to a kind of compositions with substantially control oil bacteriostasis efficacy and system thereof
Preparation Method.
Background technology
Sebum be by skin inside sebocyte cell generate, be secreted into the oil of skin surface.Prove after deliberation, sebum
Composition approximately as the triglyceride of about 57% or fatty acid, the wax ester of about 23%, the Squalene of about 12%, the steroid of about 3%
Alcohol ester, 1～the cholesterol of 2%.Particularly in heat, the summer of high humidity, the metabolism of human body self can be accelerated, body
Interior sweat gland, sebaceous gland activity can be strengthened, and cause the secretion of sebum to get more and more, and too much sebum is distributed in skin surface, just
Pore can be blocked, cause cutin the thickest, form acne, the dermatosis such as seborrheic dermatitis.
The people of oily skin, the secretion of sebaceous gland is more vigorous, and facial perception is greasy, the most easy to clean.Corse sweat pore is usual
Owing to hormone in vivo parasecretion, pressure are excessive and environmental pollution, cleaning the reason such as are not carried out and caused.Along with the age
The appearance of the problem such as growth, environmental pollution, computer radiate, operating pressure are increasing, thus skin is caused many bad shadows
Ringing, the people of mixed skin gets more and more, and except groups of people are born mixed skin, some people is from neutral skin
Skin or oily skin are transformed into mixed skin.The formation of Combination or oily skin is precisely due to skin oil and fat supersecretion is made
Becoming, fat secretion is too much, and the oils and fats support that pore can be stacked is big.Additionally, with advancing age, skin gradually loses bullet
Property, perifollicolar lacks supporting construction, is also easy to make pore seem bigger；Corse sweat pore is puzzlement oiliness and mixing skin
Greatest problem.
In the cosmetics of existing control oils, in order to control or regulate sebum secretion, a class uses some oil suction powder to become
Point, these powder have the structure of hollow, it is possible to the excess oil on upper absorption skin largely, such as: nylon powder, nitrogen
Change boron powder, Talcum, silicon dioxide, polymethyl methacrylate etc.；These composition major parts are synthetic ingredient or mineralogical composition,
In addition to absorbing unnecessary sebum, it is difficult to there is further effect.Another big class is through chemical action, and it can reduce
The quantity of skin activity sebum body of gland, it is possible to reduce the fat secretion ability of skin activity sebaceous gland, thus reach oil-control
Excessive secretion.The control oil product of both types, owing to effect is more single, its control oil less effective, the most antibacterial
Effect, the skin overdrying that life-time service even can produce, or become the most soft situation.
It addition, in order to reach preferable removing acnes and controlling oil effect, often there is interpolation in the anti-acne product of Cosmetic Market
Hormone, antibiotic and some other disabling limit the use of composition, and these situations are very universal, and product uses and there is potential safety hazard.
Summary of the invention
In order to solve the above-mentioned problems in the prior art, the present invention provides a kind of control oil with natural origin antibacterial
The compositions of effect, said composition can persistently control skin oil and fat secretion, can absorb the unnecessary oils and fats of skin secretion simultaneously,
There is good antibacterial bacteriostatic effect, it is not necessary to add preservative.
The technical purpose of the present invention is achieved through the following technical solutions:
The compositions with control oil bacteriostasis efficacy of the present invention, its formula includes each component of following mass percent:
PEG-20 methyl sesquistearate 0.8%～3.0%, isooctadecanol isostearate 1.0%～5.0%, methyl Portugal
Sugar sesquistearate 1.0%～2.0%, isononyl isononanoate 2.0%～6.0%, glycerol 2.0%～8.0%, hyaluronic acid
Sodium 0.02%～0.1%, thickening agent 0.08%～0.3%, octyl group succinic acid aluminum starch 0.5%～3.0%, propylene glycol 0.8%
～5.0%, anti-sensitizer 0.1%～0.3%, Biopol β 2.0%～5.0%, glucosan 1.0%～3.0%, Radix Hamamelidis Mollis extract
Liquid 1.0%～5.0%, surplus are deionized water.
Preferably, the Particle size requirements of described octyl group succinic acid aluminum starch is: 95%～99% passes through 100 mesh sieves.
Wherein, described Biopol β buys to Qi company of Austria of the U.S., and the modified Portugal that this water-soluble products derives from Rhizoma amorphophalli root is sweet
Dew polysaccharide and the activity extract of black bark of willow, can regulate facial glossy and suppress the microorganism species causing acne to generate.Pungent
Base succinic acid aluminum starch (hereinafter referred to as DRY FLO PC) is to buy to Akzo Nobel N.V., is hydrophobic through degenerative treatments
Property degeneration starch, be applicable to various personal care product, it is provided that fine and smooth soft and smooth, the velvety sensation that uses, can be by
It is widely used in various talcum powder and spats powder, becomes talcous " natural " sub.Radix Hamamelidis Mollis is the sky that U.S. FDA is assert
So, efficient astringent.The leaf of Radix Hamamelidis Mollis and bark contain 8～10% tannic acid (mainly by hamameli tannin and Galla Turcica (Galla Helepensis)
Tannin etc. form), there is releiving, restrain and haemostatic effect.
Further, described formula includes each component of following mass percent: PEG-20 methyl sesquialter stearic acid
Ester 0.8%～1.0%, isooctadecanol isostearate 2.0%～5.0%, methyl sesquistearate 1.0%～
2.0%, isononyl isononanoate 2.0%～3.0%, glycerol 5.0%～8.0%, hyaluronate sodium 0.02%～0.05%, thickening
Agent 0.08%～0.3%, octyl group succinic acid aluminum starch 2.0%～3.0%, propylene glycol 3.0%～5.0%, anti-sensitizer 0.1%～
0.3%, Biopol β 2.0%～3.0%, glucosan 2.0%～3.0%, Radix Hamamelidis Mollis extracting solution 1.0%～3.0%, surplus are
Deionized water.
Further, its formula includes each component of following mass percent to the present invention: PEG-20 methyl times semihard
Fat acid ester 1.0%～3.0%, isooctadecanol isostearate 1.0%～5.0%, methyl sesquistearate 1.2%～
2.0%, isononyl isononanoate 2.0%～6.0%, glycerol 2.0%～5.0%, hyaluronate sodium 0.05%～0.10%, thickening
Agent 0.1%～0.3%, octyl group succinic acid aluminum starch 0.5%～3.0%, propylene glycol 0.8%～5.0%, anti-sensitizer 0.2%～
0.3%, Biopol β 2.0%～5.0%, glucosan 1.0%～3.0%, Radix Hamamelidis Mollis extracting solution 3.0%～5.0%, surplus are
Deionized water.
Specifically, during described thickening agent is xanthan gum, carbomer, cellulose thickener, carrageenan one or both with
On combination.
Specifically, the one during described anti-sensitizer is bisabolol, Rhizoma Zingiberis Recens extract, glycyrrhizic acid dipotassium, allantoin or two
Plant above combination.
Another technical purpose of the present invention is to provide a kind of method preparing the above-mentioned compositions with control oil bacteriostasis efficacy, bag
Include following steps:
1). by the PEG-20 methyl sesquistearate of formula ratio, isooctadecanol isostearate, methyl times
Semi-solid fat acid esters, isononyl isononanoate are sequentially added in emulsifying pot, open stirring, be warming up to 70～80 DEG C, insulation 10～
15min, as A group component；
2). by the xanthan gum of formula ratio, hyaluronate sodium glycerol moistening, then add deionized water, stir and be warming up to
70～80 DEG C, insulation 10～15min is to being completely dissolved, as B group component；The mixing speed of emulsifying pot be maintained at 25～30 turns/
Min, sucks B phase vacuum in described emulsifying pot, high speed homogenization 8～10min, is cooled to 40～45 DEG C；
3). octyl group succinic acid aluminum starch is added in propylene glycol, stirs, as C group component, be subsequently adding emulsifying pot
In；
4). will add successively as the bisabolol of D group component, phenoxyethanol, Biopol β, glucosan, Radix Hamamelidis Mollis extracting solution
Enter in emulsifying pot, stir to being completely dispersed uniformly, be down to discharging when 35～40 DEG C.
Beneficial effects of the present invention:
Compared with commercially available oil control and acne removal product, control oil component that present invention uses natural origin, that safety is high,
Through scientific and reasonable collocation, showing obvious performance advantage at aspects such as controlling oily, antibacterial, anti-acne, skinfeel, experiment shows,
This product high safety, without any side effects.The present invention have control oil bacteria inhibiting composition hinge structure have with
Under feature:
1, the compositions of the control oil bacteriostasis efficacy of the present invention can reduce the greasy feeling of the formula such as emulsion, cream, oil wax, can have
Effect absorbs the excess oil on skin, has significantly control oil effect, can reduce the growth of antibacterial simultaneously.
2, the compositions of the control oil bacteriostasis efficacy of the present invention uses the natural origin control antibacterial component of oil, and its mildness is the most excellent
In salicylate, it is possible to promote that the renewal of epidermis cell, suppression cause the skin flora that acne is formed, have the most antibacterial dispelling
Pox effect.It can also reduce the surface tension of oils and fats, promotes it to be dispersed into fine oil droplets, and these little oil droplets are dispersed in skin
Skin surface, can visually weaken the greasy feeling even eliminating skin.
3, owing to the compositions of the control oil bacteriostasis efficacy of the present invention with the addition of, there is antibacterial action component, so can in product
With without preservative, the safety of product is the highest.
4, the compositions of the control oil bacteriostasis efficacy of the present invention contains the multiple functional component releived and repair, beneficially pox print flesh
The reparation of skin.
Detailed description of the invention
The natural control antibacterial elite Biopol β of oil of the present invention, this water-soluble products derives from the modified Portugal manna of Rhizoma amorphophalli root
Polysaccharide and the activity extract of black bark of willow, can regulate microorganism species that is facial glossy and that suppress to cause acne, be that solution is many
The up-to-date breakthrough of oily skin.Glucomannan is the heteropolysaccharide of high molecular, is made up of glucose and mannose.And Rhizoma amorphophalli root
Powder extracts, rich in glucomannan, is the splendid source of carbohydrate.By a series of distinctive chemical reactions, by alkane
Base sulfonate chain is grafted onto on the branched group of polysaccharide molecule, improves the structure of this carbohydrate, formed the most hydrophilic but also
The molecule of oleophylic.
Biopol β contains black bark of willow extracting solution, and black bark of willow extracting solution contains natural beta-hydroxy acid active substance,
But not having the zest of salicylate, black bark of willow extracting solution is as gentle analgesic, and preservative and antiinflammatory make
With having the longest history.Verified, it can promote that the renewal of epidermis cell, suppression cause the skin bacteria that acne is formed
Group.It can reduce the surface tension of oils and fats, promotes it to be dispersed into fine oil droplets.These little oil droplets are dispersed in skin table
Face, can visually weaken the greasy feeling even eliminating skin.When cosmetics, it can control sebum on a skin surface
Flowing, alleviate greasy outward appearance, make dermal sensation salubrious.And the natural salicylic acid activity contained by black bark of willow extracting solution
Thing, then have renewal cell and antibacterial function, simultaneously almost without stimulation.
Octyl group succinic acid aluminum starch is bought to Akzo Nobel N.V., and its name of product is Dry Flo PC, and it is freely
Flowing, young thin particle size (Particle size requirements is: 95%～99% by the sieve of 100 mesh), sufficiently small particle diameter make it have
There is sensation soft, velvety, there is hydrophobicity and water proofing property.It can significantly reduce the greasy feeling of emulsion, cream and ointment.
It absorbs unnecessary oils and fats and moisture content from face and health, it is provided that the most smooth a kind of skinfeel.
In order to make the object, technical solutions and advantages of the present invention definitely, below the preferred embodiments of the present invention are entered
The description that row is detailed.In the embodiment of the present invention weight of each component can be kilogram or kilogram.
Below by way of specific example, the present invention is further elaborated, but the present invention is not limited to this specific examples.
1、Embodiment 1～3 and the formula of compositions of reference examples 1
The formula of table 1 compositions
2. the preparation technology of the compositions of embodiment 1～3
1) raw material of A group component is sequentially added in emulsifying pot, open stirring, be warming up to 70～80 DEG C, insulation 10～
15min。
2) deionized water is added in aqueous phase pot, by the xanthan gum in B group component, hyaluronate sodium glycerol moistening, so
In rear addition aqueous phase pot, open stirring, be warming up to 80 DEG C, be incubated 10min, until being completely dissolved.
3) mixing speed of emulsifying pot is maintained at 30 turns/min, by vacuum, B group component is sucked emulsifying pot, at a high speed
(2500 revs/min～3000 revs/min) homogenizing 8min, starts cooling, is down to 45 DEG C.
4) the Dry Flo PC of component C is added in propylene glycol, stir, add in emulsifying pot.
5) D group component being sequentially added into emulsifying pot successively, stirring, until being completely dispersed uniformly, is down to when 35～40 DEG C go out
Material, it is qualified to check, discharging fill.
The preparation method of reference examples 1 is identical with the preparation method of embodiment 1～3.
3. measure of merit
The compositions with control oil bacteriostasis efficacy of the present invention, by following three performance tests:
One, antibiotic effect evaluation
Antibiotic effect is tested: test basis and the method for analysis: survey by EU criteria USP51, BP2002XVI C antibacterial efficacy
Examination measures cosmetics and supports the efficiency of resisting microbial contamination, asks for an interview table 2～5.
Table 2 embodiment 1 antibiotic effect is tested
Table 3 embodiment 2 antibiotic effect is tested
Table 4 embodiment 3 antibiotic effect is tested
Table 5 conclusion criterion
Experimental result: the antibacterial system of embodiment 1～3 is tested by challenge, microorganism is had the strongest by this antibacterial system
Press down and kill effect, product is difficult to the pollution of microorganism when producing, storing and use.
Two, human skin patch
The compositions with control oil bacteriostasis efficacy of the present invention contains natural black bark of willow extracting solution and modified starch, formula
In without any chemical preservative, product has the safety of height, and product has passed through human body skin patch test, test side
Method and result show as follows:
Evaluation methodology:
1.1 tested materials: embodiment 1～3, reference examples 1 (commercially available control olein China breast).
1.2 negative controls: blank.
1.3 experimenters: totally 25 people, male 12 people, female 13 people, age 18～30 years old, meet experimenter and volunteer inclusion criteria.
Speckle method for testing: select qualified speckle examination device, with closed patch test method, by tested material about 0.02ml～
0.025ml is applied in speckle examination device, and external special adhesive tape is pasted on experimenter's forearm song side, removes tested material, in going after 24 hours
Except 30min after tested material speckle examination device, after impression disappears, observe dermoreaction, by " cosmetics health specification " (version in 2007)
Dermoreaction grade scale records its result.
1.4 evaluation of result: record reaction result by table 6 (skin adverse reaction grade scale).
Table 6 skin adverse reaction grade scale
Result of the test is shown in Table 7:
Table 7 cosmetics human skin patch result
Result above shows: in embodiment 1～3,25 subjects skin's the most negative (grading system: 0 grade).
According to " cosmetics health specification " (version in 2007) human body skin class patch test criterion, sample is bad instead without skin to human body
Should, embodiment all has good safety.Reference examples 1 has 2 example 1 order reactions, and the safety of product is not good enough.
Three, long-acting oil control effect experimental
Choosing 120 oiliness or the volunteer of mixed skin, the age was 18～40 one full year of life, is divided into 4 groups, often organizes 30 people.
Using method: the use time is surrounding, twice daily by patented product of the present invention (embodiment 1～3) and reference examples 1
(commercially available control olein China breast) spreads upon the forehead left and right sides of experimenter, cosmetic obtained in each embodiment of relative analysis respectively
The control oil effect of product.Wherein, described control oil effect is glossy, the improvement situation of corse sweat pore, blackhead of face, and result see table
8:
Experimental result: the compositions with control oil bacteriostasis efficacy of embodiment 1～3 does not all find to stimulate during on probation
Property and allergic phenomena.Reference examples 1 has 2 volunteers the situation of allergy occur.Experiment results proved, each product pair of embodiment 1～3
The improvement degree of face glossy, corse sweat pore, blackhead is apparently higher than matched group 1.
Obviously, the above embodiment of the present invention is only for clearly demonstrating example of the present invention, and is not right
The restriction of embodiments of the present invention.For those of ordinary skill in the field, the most also may be used
To make other changes in different forms.Here cannot all of embodiment be given exhaustive.Every belong to this
What bright technical scheme was extended out obviously changes or changes the row still in protection scope of the present invention.
Claims (7)
1. a compositions with control oil bacteriostasis efficacy, it is characterised in that its formula includes each group of following mass percent
Point: PEG-20 methyl sesquistearate 0.8%～3.0%, isooctadecanol isostearate 1.0%～5.0%, methyl
Glucose sesquistearate 1.0%～2.0%, isononyl isononanoate 2.0%～6.0%, glycerol 2.0%～8.0%, hyalomitome
Acid sodium 0.02%～0.1%, thickening agent 0.08%～0.3%, octyl group succinic acid aluminum starch 0.5%～3.0%, propylene glycol
0.8%～5.0%, anti-sensitizer 0.1%～0.3%, Biopol β 2.0%～5.0%, glucosan 1.0%～3.0%, gold thread
Prunus mume (sieb.) sieb.et zucc. extracting solution 1.0%～5.0%, surplus are deionized water.
The compositions with control oil bacteriostasis efficacy the most according to claim 1, it is characterised in that described octyl group succinic acid aluminum
The Particle size requirements of starch is: 95%～99% by the sieve of 100 mesh.
The most according to claim 1 and 2 have control oil bacteriostasis efficacy compositions, it is characterised in that its formula include as
Each component of lower mass percent: PEG-20 methyl sesquistearate 0.8%～1.0%, isooctadecanol isostearic acid
Ester 2.0%～5.0%, methyl sesquistearate 1.0%～2.0%, isononyl isononanoate 2.0%～3.0%, glycerol
5.0%～8.0%, hyaluronate sodium 0.02%～0.05%, thickening agent 0.08%～0.3%, octyl group succinic acid aluminum starch
2.0%～3.0%, propylene glycol 3.0%～5.0%, anti-sensitizer 0.1%～0.3%, Biopol β 2.0%～3.0%, glucosan
2.0%～3.0%, Radix Hamamelidis Mollis extracting solution 1.0%～3.0%, surplus are deionized water.
The most according to claim 1 and 2 have control oil bacteriostasis efficacy compositions, it is characterised in that its formula include as
Each component of lower mass percent: PEG-20 methyl sesquistearate 1.0%～3.0%, isooctadecanol isostearic acid
Ester 1.0%～5.0%, methyl sesquistearate 1.2%～2.0%, isononyl isononanoate 2.0%～6.0%, glycerol
2.0%～5.0%, hyaluronate sodium 0.05%～0.10%, thickening agent 0.1%～0.3%, octyl group succinic acid aluminum starch
0.5%～3.0%, propylene glycol 0.8%～5.0%, anti-sensitizer 0.2%～0.3%, Biopol β 2.0%～5.0%, Portugal gather
Sugar 1.0%～3.0%, Radix Hamamelidis Mollis extracting solution 3.0%～5.0%, surplus are deionized water.
The compositions with control oil bacteriostasis efficacy the most according to claim 3, it is characterised in that described thickening agent is xanthan
One or more combination in glue, carbomer, cellulose thickener, carrageenan.
The compositions with control oil bacteriostasis efficacy the most according to claim 3, it is characterised in that described anti-sensitizer is red not have
One or more combination in medicine alcohol, Rhizoma Zingiberis Recens extract, glycyrrhizic acid dipotassium, allantoin.
7. prepare the method that having as described in any one in claim 1～6 controls the compositions of oil bacteriostasis efficacy, its
It is characterised by, comprises the following steps:
1). by the PEG-20 methyl sesquistearate of formula ratio, isooctadecanol isostearate, methyl times semihard
Fat acid ester, isononyl isononanoate are sequentially added in emulsifying pot, open stirring, are warming up to 70～80 DEG C, are incubated 10～15min, make
For A group component；
2). by the xanthan gum of formula ratio, hyaluronate sodium glycerol moistening, then add deionized water, stir and be warming up to 70～
80 DEG C, insulation 10～15min is to being completely dissolved, as B group component；The mixing speed of emulsifying pot is maintained at 25～30 turns/min,
B phase vacuum is sucked in described emulsifying pot, high speed homogenization 8～10min, be cooled to 40～45 DEG C；
3). octyl group succinic acid aluminum starch is added in propylene glycol, stirs, as C group component, be subsequently adding in emulsifying pot；
4). will be sequentially added in emulsifying pot as the bisabolol of D group component, Biopol β, glucosan, Radix Hamamelidis Mollis extracting solution,
Stir to being completely dispersed uniformly, be down to discharging when 35～40 DEG C.
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