CN106132978A - 一种生物聚合物衍生物的合成方法,该生物聚合物衍生物及其用途 - Google Patents

一种生物聚合物衍生物的合成方法,该生物聚合物衍生物及其用途 Download PDF

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Publication number
CN106132978A
CN106132978A CN201580009721.1A CN201580009721A CN106132978A CN 106132978 A CN106132978 A CN 106132978A CN 201580009721 A CN201580009721 A CN 201580009721A CN 106132978 A CN106132978 A CN 106132978A
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Prior art keywords
biopolymer
chitosan
modifier
molecule
derivative
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Pending
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CN201580009721.1A
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English (en)
Chinese (zh)
Inventor
W·巴尔
I·扎维沙
T·弗龙奇兹科
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Institute of Biochemistry and Biophysics, Polish Academy of Sciences
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Institute of Biochemistry and Biophysics, Polish Academy of Sciences
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Priority claimed from PL407258A external-priority patent/PL235482B1/pl
Priority claimed from PL407257A external-priority patent/PL234156B1/pl
Application filed by Institute of Biochemistry and Biophysics, Polish Academy of Sciences filed Critical Institute of Biochemistry and Biophysics, Polish Academy of Sciences
Publication of CN106132978A publication Critical patent/CN106132978A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/10—Peptides being immobilised on, or in, an organic carrier the carrier being a carbohydrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
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    • A61K38/063—Glutathione
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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D105/00—Coating compositions based on polysaccharides or on their derivatives, not provided for in groups C09D101/00 or C09D103/00
    • C09D105/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B23/00—Obtaining nickel or cobalt
    • C22B23/04—Obtaining nickel or cobalt by wet processes
    • C22B23/0453—Treatment or purification of solutions, e.g. obtained by leaching
    • C22B23/0461—Treatment or purification of solutions, e.g. obtained by leaching by chemical methods
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B3/00—Extraction of metal compounds from ores or concentrates by wet processes
    • C22B3/20—Treatment or purification of solutions, e.g. obtained by leaching
    • C22B3/44—Treatment or purification of solutions, e.g. obtained by leaching by chemical processes
    • A—HUMAN NECESSITIES
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    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/51—Chelating agents
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    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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CN201580009721.1A 2014-02-19 2015-02-19 一种生物聚合物衍生物的合成方法,该生物聚合物衍生物及其用途 Pending CN106132978A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PLP.407257 2014-02-19
PL407258A PL235482B1 (pl) 2014-02-19 2014-02-19 Sposób syntezy pochodnej chitozanu, pochodna chitozanu otrzymana tym sposobem, kompozycja kosmetyczna zawierająca pochodną chitozanu i zastosowanie pochodnej chitozanu
PL407257A PL234156B1 (pl) 2014-02-19 2014-02-19 Pochodna polioligosacharydu, chitation i kompozycja farmaceutyczna zawierająca chitation do zastosowania do zapobiegania alergii wywołanej metalami ciężkimi
PLP.407258 2014-02-19
PCT/PL2015/000023 WO2015126269A1 (en) 2014-02-19 2015-02-19 Method for synthesis of a biopolymer derivative, a biopolymer derivative and its use

Publications (1)

Publication Number Publication Date
CN106132978A true CN106132978A (zh) 2016-11-16

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CN201580009721.1A Pending CN106132978A (zh) 2014-02-19 2015-02-19 一种生物聚合物衍生物的合成方法,该生物聚合物衍生物及其用途

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Country Link
US (1) US20170056508A1 (cg-RX-API-DMAC7.html)
EP (1) EP3107941B1 (cg-RX-API-DMAC7.html)
JP (1) JP2017513962A (cg-RX-API-DMAC7.html)
KR (1) KR20160122828A (cg-RX-API-DMAC7.html)
CN (1) CN106132978A (cg-RX-API-DMAC7.html)
AU (1) AU2015219586A1 (cg-RX-API-DMAC7.html)
BR (1) BR112016018758B1 (cg-RX-API-DMAC7.html)
CA (1) CA2938964A1 (cg-RX-API-DMAC7.html)
CL (1) CL2016002063A1 (cg-RX-API-DMAC7.html)
DK (1) DK3107941T3 (cg-RX-API-DMAC7.html)
EA (1) EA201691655A1 (cg-RX-API-DMAC7.html)
IL (1) IL247393A0 (cg-RX-API-DMAC7.html)
MX (1) MX2016010696A (cg-RX-API-DMAC7.html)
SG (2) SG10201806997QA (cg-RX-API-DMAC7.html)
WO (1) WO2015126269A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109569240A (zh) * 2018-12-14 2019-04-05 山东汇之蓝环保科技有限公司 高效脱硝离子液及其使用方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109847572A (zh) * 2018-12-24 2019-06-07 深圳市寰保化工科技有限公司 一种微生物气泡液及其制备方法和应用
JP7587928B2 (ja) * 2020-05-15 2024-11-21 株式会社 資生堂 金属アレルギー原因物質ブロック剤
CN113521110B (zh) * 2021-07-12 2023-04-07 深圳零一生命科技有限责任公司 一种缓释抗逆性益生菌晶球及其制备方法
CN113842464B (zh) * 2021-09-24 2023-07-04 江苏贝美医疗科技有限公司 一种类风湿因子吸附材料及其制备方法与应用
AR130056A1 (es) * 2022-08-02 2024-10-30 Kannar Earth Science Ltd Composiciones y métodos para controlar patógenos de plantas que incluyen nematodos
CN116036358B (zh) * 2022-12-29 2026-02-06 南京大学 一种三维打印抗菌水凝胶材料及其制备方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101759812A (zh) * 2009-12-28 2010-06-30 中国药科大学 一种新型仿穿膜肽结构的壳聚糖衍生物
CN102133433A (zh) * 2011-03-09 2011-07-27 中国人民解放军军事医学科学院基础医学研究所 一种可注射性心肌组织工程产品及其制备方法
CN103266153A (zh) * 2013-06-17 2013-08-28 江西科技师范大学 一种改性壳聚糖的生产方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992009636A1 (en) 1990-11-30 1992-06-11 Baker Cummins Dermatologicals, Inc. Skin protective compositions and method of inhibiting skin irritation
CA2126132A1 (en) 1994-06-17 1995-12-18 Witold Neugebauer Peptide synthesis on chitosan
JP4008977B2 (ja) * 1997-01-27 2007-11-14 株式会社キレスト技研 キトサン誘導体及びその製法並びに金属イオン吸着剤
US20070299034A1 (en) * 2002-02-12 2007-12-27 Marie-France Versali Cell wall derivatives, their preparation process, and use thereof
DE10338110A1 (de) 2003-08-15 2005-03-10 Biomet Deutschland Gmbh Mit Chitosan beschichteter metallischer Gegenstand sowie Verfahren zu dessen Herstellung
RU2357738C2 (ru) 2007-07-09 2009-06-10 Государственное образовательное учреждение высшего профессионального образования "КРАСНОЯРСКАЯ ГОСУДАРСТВЕННАЯ МЕДИЦИНСКАЯ АКАДЕМИЯ ФЕДЕРАЛЬНОГО АГЕНТСТВА ПО ЗДРАВООХРАНЕНИЮ И СОЦИАЛЬНОМУ РАЗВИТИЮ" Способ профилактики платиноза кожи
CA2869821C (en) * 2011-06-13 2018-06-19 Rival, Societe En Commandite N,n,n-trialkylaminopolymers, methods of their preparation and uses thereof
PL233402B1 (pl) * 2012-08-03 2019-10-31 Inst Biochemii I Biofizyki Polskiej Akademii Nauk Sposób oczyszczania ścieków o wysokiej zawartości metali, zwłaszcza srebra i miedzi
CN104012839B (zh) * 2014-05-19 2016-04-06 中国人民解放军军事医学科学院基础医学研究所 保健品制备用壳聚糖-多肽复合物及其制备方法
CN104387503A (zh) * 2014-12-11 2015-03-04 湖南科技大学 壳聚糖-还原型谷胱甘肽聚合物的制备方法及其应用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101759812A (zh) * 2009-12-28 2010-06-30 中国药科大学 一种新型仿穿膜肽结构的壳聚糖衍生物
CN102133433A (zh) * 2011-03-09 2011-07-27 中国人民解放军军事医学科学院基础医学研究所 一种可注射性心肌组织工程产品及其制备方法
CN103266153A (zh) * 2013-06-17 2013-08-28 江西科技师范大学 一种改性壳聚糖的生产方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
宋江选等: "改性壳聚糖在重金属离子吸附方面的研究进展", 《化工时刊》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109569240A (zh) * 2018-12-14 2019-04-05 山东汇之蓝环保科技有限公司 高效脱硝离子液及其使用方法

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