CN106072559A - A kind of health product for protecting the liver and its preparation method and application - Google Patents

A kind of health product for protecting the liver and its preparation method and application Download PDF

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CN106072559A
CN106072559A CN201610498274.7A CN201610498274A CN106072559A CN 106072559 A CN106072559 A CN 106072559A CN 201610498274 A CN201610498274 A CN 201610498274A CN 106072559 A CN106072559 A CN 106072559A
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weight portion
raw material
liver
fine powder
obtains
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傅志勇
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The present invention relates to a kind of health product for protecting the liver and its preparation method and application, described health product use multiple natural food materials as raw material, Pleurotus eryngii in raw material components, Auricularia, Fructus Lycii play the effect of lowering fat and protecting liver jointly, in addition Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis play regulation blood fat, effect of blood pressure lowering jointly, add Caulis et Folium Tritici aestivi extract, yeast rich in selenium, guar gum and Folium Pini extract further as effect component;Above-mentioned each raw material components coordinates compatibility, mutual gain, jointly plays the effect of protecting liver and expelling toxin, hypertension and hyperlipemia, treating both the principal and secondary aspects of a disease, good effect, and natural food materials and has no side effect, and discharges toxin, improve immunity while alleviating burden of liver.

Description

A kind of health product for protecting the liver and its preparation method and application
Technical field
The invention belongs to technical field of pharmaceuticals, be specifically related to a kind of health product for protecting the liver and preparation method thereof and answer With.
Background technology
Hepatopathy refers to the acute and chronic hepatopathy that viral hepatitis, fatty liver, alcoholic liver and other cause of disease cause.Except disease Outside poison infects, various damage hepar damnifications caused by liver factor, all it may happen that the Fibrotic disease of hepatic necrosis, inflammation secondary Reason feature.Hepatic injury is not an independent name of disease, but a kind of pathological change, is the common pathologic basis of various hepatopathy.
Chemistry and drug induced injury are the livers caused with factors such as chemotoxic substances such as carbon tetrachloride, D-Gal amine Dirty acute and chronic damage.Hepatic fibrosis refer to hepatocyte necrose, inflammatory stimulus time, the extracellular base such as collagen protein in liver The hypertrophy of matter and degraded disequilibrium, and then cause the pathological process of fibrous connective tissue abnormal deposition in liver, the lighter is referred to as Fibrosis, severe one and then make the reconstruction of lobules of liver structure, pseudolobuli and tuberosity be formed, referred to as liver cirrhosis.Owing to hepatic fibrosis is formed Mechanism is extremely complex, has cause of disease multiformity, progress gradually changeable, a feature such as the most intractable, and western medicine often just for In a certain respect or a certain link, it is difficult to obtain satisfied effect.Therefore, develop new hepatic and there is important application valency Value.
Summary of the invention
In order to solve the problems referred to above that prior art exists, the invention provides one and can effectively alleviate burden of liver, row Go out toxin, good effect, have no side effect for health product of protecting the liver and its preparation method and application.
The technical solution adopted in the present invention is:
A kind of health product for protecting the liver, raw material components includes:
Caulis et Folium Tritici aestivi extract 15-25 weight portion, Rhizoma amorphophalli 15-25 weight portion, yeast rich in selenium 2-8 weight portion, Pleurotus eryngii 15-25 Weight portion, guar gum 15-25 weight portion, thunderbolt fruit 2-8 weight portion, Semen Castaneae 2-8 weight portion, Rhizoma Solani tuber osi 10-20 weight portion, black wood Ear 10-20 weight portion, Fructus Lycii 10-20 weight portion, Folium Pini extract 5-15 weight portion, Rhizoma Phragmitis 5-15 weight portion.
The raw material components of the most described health product for protecting the liver includes: Caulis et Folium Tritici aestivi extract 18-22 weight Part, Rhizoma amorphophalli 18-22 weight portion, yeast rich in selenium 4-6 weight portion, Pleurotus eryngii 18-22 weight portion, guar gum 18-22 weight portion, thunderclap Thunderbolt fruit 4-6 weight portion, Semen Castaneae 4-6 weight portion, Rhizoma Solani tuber osi 12-16 weight portion, Auricularia 12-16 weight portion, Fructus Lycii 12-16 weight Part, Folium Pini extract 8-12 weight portion, Rhizoma Phragmitis 8-12 weight portion.
A kind of method preparing the described health product for protecting the liver, comprises the steps:
(1) weigh described Pleurotus eryngii, Auricularia and Fructus Lycii, be dried respectively, after pulverization process, obtain each raw material Fine powder;Carry out the fine powder of described each raw material being sufficiently mixed uniformly, obtain the first mixed material;
(2) in described first mixed material, add 5-10 times of quality water to decoct, obtain decoction liquor;By described decoction Liquid carries out filtering, concentrating successively, obtains the first concentrate that relative density is 1.1-1.3g/ml, is entered by described first concentrate Row is dried, pulverizes, and obtains the first premix material, stand-by;
(3) weigh described Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis successively, be dried respectively, after pulverization process, Fine powder to each raw material;The fine powder of described each raw material is sufficiently mixed, obtains the second mixed material;
(4) in described second mixed material, add the ethanol of 6-9 times of volume and 40-80 DEG C of reflux, extract, 1-2h, return Extracting solution is obtained after receiving ethanol;Carrying out described extracting solution successively filtering, concentrating, obtaining relative density is 1.2-1.4g/ml's Second concentrate, is dried described second concentrate, pulverizes, and obtains the second premix material, stand-by;
(5) weigh described Caulis et Folium Tritici aestivi extract, yeast rich in selenium, guar gum and Folium Pini extract successively, do respectively After dry, pulverization process, obtain the fine powder of each raw material;The fine powder of described each raw material is sufficiently mixed, obtains the 3rd mixture Material;
(6) in described 3rd mixed material, add the ethanol of 2-7 times of volume and 60-90 DEG C of reflux, extract, 1-4h, return Extracting solution is obtained after receiving ethanol;Carrying out described extracting solution successively filtering, concentrating, obtaining relative density is 1.3-1.6g/ml's 3rd concentrate, is dried described 3rd concentrate, pulverizes, and obtains the 3rd premix material, stand-by;
(7) described for step (2) the first premix material, described second premix material of step (4) and step (6) the 3rd premix material are entered Row is sufficiently mixed uniformly, obtains described for the health product protected the liver.
In step (1), the granularity of described each raw material fine powder is 110-130 mesh.
In step (2), described decoction repeats three times, the decoction liquor of three gained is merged;The time every time decocted It is 30-60min;
In step (2), the temperature carrying out described concentration is 70-90 DEG C, carries out described dry temperature and is 110-130 DEG C, Carrying out the described dry time is 0.5-1.5h.
In step (3), the granularity of the fine powder of described each raw material is 80-110 mesh.
In step (4), the volume fraction of the ethanol of addition is 85-95%;The temperature carrying out described concentration is 60-80 DEG C, Carrying out described dry temperature and be 100-120 DEG C, carrying out the described dry time is 1-2h.
In step (5), the granularity of the fine powder of described each raw material is 120-150 mesh.
In step (6), the volume fraction of the ethanol of addition is 75-85%;The temperature carrying out described concentration is 40-60 DEG C, Carrying out described dry temperature and be 80-100 DEG C, carrying out the described dry time is 2-4h.
Described health product are for preparing the application in food with effect of hepatic protection.
For the ease of understanding the present invention, below the raw material in the present invention and drug effect are further elaborated.
Caulis et Folium Tritici aestivi extract, Caulis et Folium Tritici aestivi is the Semen Tritici aestivi of a kind of uniqueness, it is possible to produce concentrates marennin, organized enzyme, ties up him Life and other important nutrient.Caulis et Folium Tritici aestivi contains abundant chlorophyll, vitamin A, vitamin C, vitamin E and vitamin B Race, and mineral calcium, magnesium, phosphorus, ferrum, selenium, and super antioxidant SOD, fiber and useful ferment.Chlorophyll and erythrocytic structure Become quite similar, difference be chlorophyllous central element be magnesium, and the central element of hemoglobin is ferrum, therefore green at picked-up leaf After element can quick synthetic hemoglobin, therefore Caulis et Folium Tritici aestivi is otherwise known as " green blood ".
Rhizoma amorphophalli, makees again mill taro, and Araeceae mill taro belongs to herbaceos perennial, and ancient Chinese is also known as goblin taro.Since ancient times Rhizoma amorphophalli just has the title of " removing intestinal sand ".Rhizoma amorphophalli is grown under sparse woods, is useful basic food, to edible animal acid food mistake Many people, collocation is eaten Rhizoma amorphophalli, can be reached food acid, soda balance.Additionally, Rhizoma amorphophalli also has horizontal blood sugar lowering, blood fat reducing, fall Pressure, dissipate poison, skin care, promote blood circulation, lose weight, relieving constipation, appetizing etc. multi-functional.
Yeast rich in selenium is exactly addition selenium element during culture yeasts, has absorbed selenium, make selenium during yeast growth Protein and polysaccharide organic in yeast body are combined and are converted into biological selenium, thus eliminate chemistry selenium (such as sodium selenite) to people The toxicity of body and the intestines and stomach stimulate, and enable that selenium is more efficient, be more safely absorbed by the body utilization.Yeast rich in selenium is also so far Till domestic the most efficiently, the selenium-replenishing preparation that equalizes most of the safest, nutrition.
Pleurotus eryngii, has another name called pleurotus eryngii, and the fragrance having Semen Armeniacae Amarum because of it and bacterial context plumpness are gained the name such as the mouthfeel of Carnis Haliotidis.It is Exploitation cultivation in recent years successfully integrates edible, medicinal, the Rare edible fungus new varieties of dietetic therapy.Pleurotus eryngii is nutritious, The mineral such as rich in proteins, carbohydrate, vitamin and calcium, magnesium, copper, zinc, can improve immune function of human body, to human body There is the effects such as anticancer, blood fat reducing, intestine moistening stomach and beauty treatment.
Guar gum is a kind of nonionic galactomannan extracted from the endosperm of leguminous plant Guar beans, melon That locust beam gum and derivant thereof have preferable water solublity, and present the highest viscosity under low quality mark.Guar gum system is by melon Endosperm fraction after the seed peeling degerming of your bean adds water after cleaning, drying and crushing, carry out pressurized hydrolysis again after with 20% Ethanol precipitates, and is dried, pulverizes and obtain after centrifugation.Commercially available glue generally white, to the free-pouring powder of fawn, connects The most odorless, also without other any abnormal flavour, typically contain the polysaccharide of 75%~85%, the protein of 5%~6%, the fibre of 2%~3% Dimension and the ash of 1%.
Thunderbolt fruit, originates from Philippine than the Cole peninsula, is a kind of senior nut.Thunderbolt fruit shell is somewhat like Fructus Canarii albi shell, uses Caramel or the kernel of butter parch, the most crisp the most fragrant but also sweet, mouthfeel to be much better than relatively common Semen Armeniacae Amarum, Fructus anacardii.Fruit contains thunderbolt There are 17 kinds of aminoacid including 8 kinds of aminoacid of needed by human, rich in mineral such as Gao Meng, calcium, phosphorus, potassium, vitamin, recklessly The Multiple components such as Radix Raphani cellulose protein.Unsaturated fatty acids be mainly olein (44.4~59.6%) and Palmic acid (32.6~ 38.2%), be easily absorbed by the body digestion, good for health.Thunderbolt fruit primary efficacy is for improving memory, regulation blood fat, delaying Senility of humanbody looks improving and the skin nourishing.
Semen Castaneae, abundant unsaturated fatty acid contained in Semen Castaneae and vitamin, hypertension, coronary heart disease and tremulous pulse can be prevented and treated The diseases such as hardening.Also have the mineral such as the most high sugar, fat, protein, calcium, phosphorus, ferrum, potassium, and vitamin C, B1, B2 etc., Building body is had to be used.
Rhizoma Solani tuber osi, has another name called Rhizoma Solani tuber osi, rich in starch, pectin, protein, potassium, citric acid, vitamin B, C dietary fiber.Often food Rhizoma Solani tuber osi building body, the potassium in Rhizoma Solani tuber osi is possible to prevent hypertension.Because when human body has too much taken the photograph salt timesharing, and internal sodium can be partially Height, potassium is not enough.Rhizoma Solani tuber osi is the optimal source of potassium.Vitamin C in Rhizoma Solani tuber osi, not only with health role to brain cell, and Blood cholesterol can also be reduced, make blood vessel have elasticity, prevent arteriosclerosis.
Auricularia, Auricularia containing the element such as protein, fat, polysaccharide and calcium, phosphorus, ferrum and carotene, vitamin B1, Vitamin B2, nicotinic acid etc., the also nutrient Han phospholipid, sterin etc..Polysaccharide physical ability in Auricularia decomposes tumor, improves the immunity of people Power, has good antitumaous effect.And this polysaccharide body also has dredging vascellum, removes the effect of cholesterol in blood vessel, so Can with blood sugar lowering, blood fat reducing, prevent thrombosis, prevention cerebrovascular disease occur.Lecithin matter in Auricularia, has brain cell Nutrition, therefore Auricularia is good supplementing the brain food.Auricularia also have nourishing moisturize, the food therapy effect of the stomach reinforcing that nourishes blood, so It it is the health food of various modern civilization diseases such as hypertension, heart disease, cancer patient.
Fructus Lycii, rich in lycium barbarum polysaccharide, lycium barbarum polysaccharide is a kind of water soluble polysaccharide, is that in Fructus Lycii, topmost activity becomes Point, relative molecular mass is 68-200, there is now a lot of research show lycium barbarum polysaccharide have promotion immunity, defying age, antitumor, Remove free radical, resisting fatigue, radioprotective, protect the liver, reproductive function protection and the effect such as improvement.
Folium Pini extract, extracts from the needle of pinaster, owing to extract is rich in Flavonoid substances, multivitamin, amino Acid and mineral, have relatively strong antioxidant action.Folium Pini extract can obviously reduce the three quasi-tradition food that fire-cure, pickle and ferment Carcinogenic risk, be natural anti-gene mutation food.
Rhizoma Phragmitis, for the rhizome of phragmites communis, Rhizoma Phragmitis decocting liquid can clearing away heat and promoting diuresis, jaundice eliminating, hepatoprotective, to reducing transaminase and recovering liver function Can there is good result.
Caulis et Folium Tritici aestivi extract of the present invention, yeast rich in selenium, guar gum, Folium Pini extract are commercially available prod.
The invention have the benefit that
1, the health product for protecting the liver of the present invention, use multiple natural food materials as raw material, in raw material components Pleurotus eryngii, Auricularia, Fructus Lycii play the effect of lowering fat and protecting liver jointly, and Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis are altogether in addition With playing regulation blood fat, effect of blood pressure lowering, Caulis et Folium Tritici aestivi extract, yeast rich in selenium, guar gum and Folium Pini extract add further Effect of strong hepatoprotective;Above-mentioned each raw material components coordinates compatibility, mutual gain, jointly plays the effect of protecting liver and expelling toxin, hypertension and hyperlipemia, Treating both the principal and secondary aspects of a disease, good effect, and natural food materials have no side effect, and discharge toxin, improve immunity while alleviating burden of liver.
2, the preparation method of the health product for protecting the liver of the present invention, by with Pleurotus eryngii, Auricularia and Fructus Lycii For raw material, carry out successively decocting, filter, concentrate, be dried, pulverize and obtain the first premix material, by with Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis, as raw material, carry out alcohol extraction successively, filter, concentrate, are dried, pulverize and obtain the second premix material;By with Semen Tritici aestivi Grass extract, yeast rich in selenium, guar gum and Folium Pini extract as raw material, carry out successively alcohol extraction, filter, concentrate, be dried, powder Broken obtain the 3rd premix material, carry out being sufficiently mixed uniformly, finally by the first premix material, the second premix material, the 3rd premix material afterwards Preparing in described health product, the effective ingredient of above-mentioned various raw materials is able to maximum reservation, and effect is worked in coordination with performance, had hepatoprotective Toxin expelling, the effect of hypertension and hyperlipemia, treating both the principal and secondary aspects of a disease, good effect, and natural food materials have no side effect, while alleviating burden of liver Discharge toxin, improve immunity.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail, represents 1g with 1 weight portion in following example.
Embodiment 1
The present embodiment provides a kind of health product for protecting the liver, and raw material components includes:
Caulis et Folium Tritici aestivi extract 15 weight portion, Rhizoma amorphophalli 25 weight portion, yeast rich in selenium 2 weight portion, Pleurotus eryngii 25 weight portion, Guar Locust beam gum 15 weight portion, thunderbolt fruit 8 weight portions, Semen Castaneae 2 weight portion, Rhizoma Solani tuber osi 20 weight portion, Auricularia 10 weight portion, Fructus Lycii 20 weight Amount part, Folium Pini extract 5 weight portion, Rhizoma Phragmitis 15 weight portion.
A kind of method preparing the described health product for protecting the liver, comprises the steps:
(1) weigh described Pleurotus eryngii, Auricularia and Fructus Lycii, be dried respectively, after pulverization process, obtain granularity and be The fine powder of the 110 each raw materials of purpose;Carry out the fine powder of described each raw material being sufficiently mixed uniformly, obtain the first mixed material;
(2) in described first mixed material, add 5 times of quality water and be heated to boiling the most with high heat, then slow fire decocts 30min, obtains decoction liquor;Described decoction liquor being filtered, filtrate concentrates at 70 DEG C, and obtaining relative density is 1.1g/ First concentrate of ml, after described first concentrate is dried 1.5h at 110 DEG C, pulverizes, obtains the first premix material, treat With;
(3) weigh described Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis successively, be dried respectively, after pulverization process, The fine powder of the 80 each raw materials of purpose it is to granularity;The fine powder of described each raw material is sufficiently mixed, obtains the second mixed material;
(4) in described second mixed material, add the ethanol (volume fraction is 85%) of 6 times of volumes, return at 40 DEG C afterwards Stream extracts 2h, obtains extracting solution after reclaiming ethanol;After being filtered by described extracting solution, filtrate concentrates at 60 DEG C, obtains Relative density is second concentrate of 1.2g/ml, after described second concentrate is dried 2h at 100 DEG C, pulverizes, obtains the Two premix material, stand-by;
(5) weigh described Caulis et Folium Tritici aestivi extract, yeast rich in selenium, guar gum and Folium Pini extract successively, do respectively After dry, pulverization process, obtain granularity and be the fine powder of the 120 each raw materials of purpose;The fine powder of described each raw material is sufficiently mixed, Obtain the 3rd mixed material;
(6) in described 3rd mixed material, add the ethanol (volume fraction is 75%) of 2 times of volumes, return at 60 DEG C afterwards Stream extracts 4h, obtains extracting solution after reclaiming ethanol;Being filtered by described extracting solution, filtrate concentrates at 40 DEG C, obtains phase To the 3rd concentrate that density is 1.3g/ml, after described 3rd concentrate is dried 4h at 80 DEG C, pulverizes, obtain the 3rd Premix material, stand-by;
(7) described for step (2) the first premix material, described second premix material of step (4) and step (6) the 3rd premix material are entered Row is sufficiently mixed uniformly, obtains described for the health product protected the liver.
Embodiment 2
The present embodiment provides a kind of health product for protecting the liver, and raw material components includes:
Caulis et Folium Tritici aestivi extract 25 weight portion, Rhizoma amorphophalli 15 weight portion, yeast rich in selenium 8 weight portion, Pleurotus eryngii 15 weight portion, Guar Locust beam gum 25 weight portion, thunderbolt fruit 2 weight portions, Semen Castaneae 8 weight portion, Rhizoma Solani tuber osi 10 weight portion, Auricularia 20 weight portion, Fructus Lycii 10 weight Amount part, Folium Pini extract 15 weight portion, Rhizoma Phragmitis 5 weight portion.
A kind of method preparing the described health product for protecting the liver, comprises the steps:
(1) weigh described Pleurotus eryngii, Auricularia and Fructus Lycii, be dried respectively, after pulverization process, obtain granularity and be The fine powder of the 130 each raw materials of purpose;Carry out the fine powder of described each raw material being sufficiently mixed uniformly, obtain the first mixed material;
(2) in described first mixed material, add 10 times of quality water and be heated to boiling the most with high heat, then slow fire decocts 30min, obtains decoction liquor;Described decoction liquor being filtered, filtrate concentrates at 90 DEG C, and obtaining relative density is 1.3g/ First concentrate of ml, after described first concentrate is dried 0.5h at 130 DEG C, pulverizes, obtains the first premix material, treat With;
(3) weigh described Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis successively, be dried respectively, after pulverization process, The fine powder of the 110 each raw materials of purpose it is to granularity;The fine powder of described each raw material is sufficiently mixed, obtains the second mixture Material;
(4) in described second mixed material, add the ethanol (volume fraction is 95%) of 9 times of volumes, return at 80 DEG C afterwards Stream extracts 1h, obtains extracting solution after reclaiming ethanol;After being filtered by described extracting solution, filtrate concentrates at 80 DEG C, obtains Relative density is second concentrate of 1.4g/ml, after described second concentrate is dried 1h at 120 DEG C, pulverizes, obtains the Two premix material, stand-by;
(5) weigh described Caulis et Folium Tritici aestivi extract, yeast rich in selenium, guar gum and Folium Pini extract successively, do respectively After dry, pulverization process, obtain granularity and be the fine powder of the 150 each raw materials of purpose;The fine powder of described each raw material is sufficiently mixed, Obtain the 3rd mixed material;
(6) in described 3rd mixed material, add the ethanol (volume fraction is 85%) of 7 times of volumes, return at 90 DEG C afterwards Stream extracts 1h, obtains extracting solution after reclaiming ethanol;Being filtered by described extracting solution, filtrate concentrates at 60 DEG C, obtains phase To the 3rd concentrate that density is 1.6g/ml, after described 3rd concentrate is dried 2h at 100 DEG C, pulverizes, obtain the 3rd Premix material, stand-by;
(7) described for step (2) the first premix material, described second premix material of step (4) and step (6) the 3rd premix material are entered Row is sufficiently mixed uniformly, obtains described for the health product protected the liver.
Embodiment 3
The present embodiment provides a kind of health product for protecting the liver, and raw material components includes:
Caulis et Folium Tritici aestivi extract 18 weight portion, Rhizoma amorphophalli 22 weight portion, yeast rich in selenium 4 weight portion, Pleurotus eryngii 22 weight portion, Guar Locust beam gum 18 weight portion, thunderbolt fruit 6 weight portions, Semen Castaneae 4 weight portion, Rhizoma Solani tuber osi 16 weight portion, Auricularia 12 weight portion, Fructus Lycii 16 weight Amount part, Folium Pini extract 8 weight portion, Rhizoma Phragmitis 12 weight portion.
A kind of method preparing the described health product for protecting the liver, comprises the steps:
(1) weigh described Pleurotus eryngii, Auricularia and Fructus Lycii, be dried respectively, after pulverization process, obtain granularity and be The fine powder of the 120 each raw materials of purpose;Carry out the fine powder of described each raw material being sufficiently mixed uniformly, obtain the first mixed material;
(2) in described first mixed material, add 8 times of quality water and be heated to boiling the most with high heat, then slow fire decocts 30min, obtains decoction liquor;Described decoction liquor being filtered, filtrate concentrates at 80 DEG C, and obtaining relative density is 1.2g/ First concentrate of ml, after described first concentrate is dried 1h at 120 DEG C, pulverizes, obtains the first premix material, stand-by;
(3) weigh described Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis successively, be dried respectively, after pulverization process, The fine powder of the 90 each raw materials of purpose it is to granularity;The fine powder of described each raw material is sufficiently mixed, obtains the second mixed material;
(4) in described second mixed material, add the ethanol (volume fraction is 90%) of 8 times of volumes, return at 60 DEG C afterwards Stream extracts 1.5h, obtains extracting solution after reclaiming ethanol;After being filtered by described extracting solution, filtrate concentrates at 70 DEG C, To the second concentrate that relative density is 1.3g/ml, after described second concentrate is dried 1.5h at 110 DEG C, pulverize, To the second premix material, stand-by;
(5) weigh described Caulis et Folium Tritici aestivi extract, yeast rich in selenium, guar gum and Folium Pini extract successively, do respectively After dry, pulverization process, obtain granularity and be the fine powder of the 130 each raw materials of purpose;The fine powder of described each raw material is sufficiently mixed, Obtain the 3rd mixed material;
(6) in described 3rd mixed material, add the ethanol (volume fraction is 80%) of 5 times of volumes, return at 75 DEG C afterwards Stream extracts 2h, obtains extracting solution after reclaiming ethanol;Being filtered by described extracting solution, filtrate concentrates at 50 DEG C, obtains phase To the 3rd concentrate that density is 1.4g/ml, after described 3rd concentrate is dried 3h at 90 DEG C, pulverizes, obtain the 3rd Premix material, stand-by;
(7) described for step (2) the first premix material, described second premix material of step (4) and step (6) the 3rd premix material are entered Row is sufficiently mixed uniformly, obtains described for the health product protected the liver.
Embodiment 4
The present embodiment provides a kind of health product for protecting the liver, and raw material components includes:
Caulis et Folium Tritici aestivi extract 22 weight portion, Rhizoma amorphophalli 18 weight portion, yeast rich in selenium 6 weight portion, Pleurotus eryngii 18 weight portion, Guar Locust beam gum 22 weight portion, thunderbolt fruit 4 weight portions, Semen Castaneae 6 weight portion, Rhizoma Solani tuber osi 12 weight portion, Auricularia 16 weight portion, Fructus Lycii 12 weight Amount part, Folium Pini extract 12 weight portion, Rhizoma Phragmitis 8 weight portion.
A kind of method preparing the described health product for protecting the liver, comprises the steps:
(1) weigh described Pleurotus eryngii, Auricularia and Fructus Lycii, be dried respectively, after pulverization process, obtain granularity and be The fine powder of the 115 each raw materials of purpose;Carry out the fine powder of described each raw material being sufficiently mixed uniformly, obtain the first mixed material;
(2) in described first mixed material, add 7 times of quality water and be heated to boiling the most with high heat, then slow fire decocts 30min, obtains decoction liquor;Described decoction liquor being filtered, filtrate concentrates at 75 DEG C, and obtaining relative density is 1.2g/ First concentrate of ml, after described first concentrate is dried 1h at 120 DEG C, pulverizes, obtains the first premix material, stand-by;
(3) weigh described Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis successively, be dried respectively, after pulverization process, The fine powder of the 100 each raw materials of purpose it is to granularity;The fine powder of described each raw material is sufficiently mixed, obtains the second mixture Material;
(4) in described second mixed material, add the ethanol (volume fraction is 90%) of 7 times of volumes, return at 60 DEG C afterwards Stream extracts 1.5h, obtains extracting solution after reclaiming ethanol;After being filtered by described extracting solution, filtrate concentrates at 70 DEG C, To the second concentrate that relative density is 1.3g/ml, after described second concentrate is dried 1.5h at 110 DEG C, pulverize, To the second premix material, stand-by;
(5) weigh described Caulis et Folium Tritici aestivi extract, yeast rich in selenium, guar gum and Folium Pini extract successively, do respectively After dry, pulverization process, obtain granularity and be the fine powder of the 140 each raw materials of purpose;The fine powder of described each raw material is sufficiently mixed, Obtain the 3rd mixed material;
(6) in described 3rd mixed material, add the ethanol (volume fraction is 78%) of 5 times of volumes, return at 75 DEG C afterwards Stream extracts 2h, obtains extracting solution after reclaiming ethanol;Being filtered by described extracting solution, filtrate concentrates at 50 DEG C, obtains phase To the 3rd concentrate that density is 1.4g/ml, after described 3rd concentrate is dried 3h at 90 DEG C, pulverizes, obtain the 3rd Premix material, stand-by;
(7) described for step (2) the first premix material, described second premix material of step (4) and step (6) the 3rd premix material are entered Row is sufficiently mixed uniformly, obtains described for the health product protected the liver.
Embodiment 5
The present embodiment provides a kind of health product for protecting the liver, and raw material components includes:
Caulis et Folium Tritici aestivi extract 20 weight portion, Rhizoma amorphophalli 20 weight portion, yeast rich in selenium 5 weight portion, Pleurotus eryngii 20 weight portion, Guar Locust beam gum 20 weight portion, thunderbolt fruit 5 weight portions, Semen Castaneae 5 weight portion, Rhizoma Solani tuber osi 14 weight portion, Auricularia 14 weight portion, Fructus Lycii 14 weight Amount part, Folium Pini extract 10 weight portion, Rhizoma Phragmitis 10 weight portion.
A kind of method preparing the described health product for protecting the liver, comprises the steps:
(1) weigh described Pleurotus eryngii, Auricularia and Fructus Lycii, be dried respectively, after pulverization process, obtain granularity and be The fine powder of the 115 each raw materials of purpose;Carry out the fine powder of described each raw material being sufficiently mixed uniformly, obtain the first mixed material;
(2) in described first mixed material, add 7 times of quality water and be heated to boiling the most with high heat, then slow fire decocts 30min, obtains decoction liquor;Described decoction liquor being filtered, filtrate concentrates at 75 DEG C, and obtaining relative density is 1.2g/ First concentrate of ml, after described first concentrate is dried 1h at 120 DEG C, pulverizes, obtains the first premix material, stand-by;
(3) weigh described Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis successively, be dried respectively, after pulverization process, The fine powder of the 100 each raw materials of purpose it is to granularity;The fine powder of described each raw material is sufficiently mixed, obtains the second mixture Material;
(4) in described second mixed material, add the ethanol (volume fraction is 90%) of 7 times of volumes, return at 60 DEG C afterwards Stream extracts 1.5h, obtains extracting solution after reclaiming ethanol;After being filtered by described extracting solution, filtrate concentrates at 70 DEG C, To the second concentrate that relative density is 1.3g/ml, after described second concentrate is dried 1.5h at 110 DEG C, pulverize, To the second premix material, stand-by;
(5) weigh described Caulis et Folium Tritici aestivi extract, yeast rich in selenium, guar gum and Folium Pini extract successively, do respectively After dry, pulverization process, obtain granularity and be the fine powder of the 140 each raw materials of purpose;The fine powder of described each raw material is sufficiently mixed, Obtain the 3rd mixed material;
(6) in described 3rd mixed material, add the ethanol (volume fraction is 78%) of 5 times of volumes, return at 75 DEG C afterwards Stream extracts 2h, obtains extracting solution after reclaiming ethanol;Being filtered by described extracting solution, filtrate concentrates at 50 DEG C, obtains phase To the 3rd concentrate that density is 1.4g/ml, after described 3rd concentrate is dried 3h at 90 DEG C, pulverizes, obtain the 3rd Premix material, stand-by;
(7) described for step (2) the first premix material, described second premix material of step (4) and step (6) the 3rd premix material are entered Row is sufficiently mixed uniformly, obtains described for the health product protected the liver.
Experimental example
Clinical 100 example hepatopaths are applied these health product to observe by the present inventor, wherein minimum 35 years old of age, maximum 81 years old, male 50, women 50.
Application process: oral, every day 2-3 time, each 10-15g, one week is a course for the treatment of.
Efficacy assessment standard:
Curing: clinical efficacy is notable, liver function indices is normal, 68 examples.
Effective: clinical symptoms is controlled, liver function indices close to normal value, 27 examples.
Invalid: liver function indices is not improved 5 examples.
Total effective rate 95%.
Typical clinical case:
Solemn certain, 35 years old, man, patient often felt abdominal distention, weak, upper right abdomen severe pain or tenderness, has the disease such as heating, leukocytosis Shape, detects through B ultrasonic and liver function index, is diagnosed as moderate fatty liver, takes health product described in the embodiment of the present invention 13 treatment Journey, checks to hospital, and fatty liver disappears, and every liver function index recovers normal value, cures.
Huge certain, 55 years old, man, be addicted to drink, patient often feels limbs fatigue, and right shoulder and back ache is swollen, and feels very for no reason at all Tired, dizzy, detect through B ultrasonic and liver function index, be diagnosed as severe fatty liver, take health product 4 described in the embodiment of the present invention 2 The individual course for the treatment of, checking to hospital, fatty liver disappears, and every liver function index recovers normal value, cures.
High certain, 40 years old, female, patient's appetite declined, and often feels weak, feels sick, has the symptoms such as vomiting, stomachache, through liver function Can Indexs measure, be diagnosed as hepatitis A, take 2 courses for the treatment of of health product described in the embodiment of the present invention 3, check to hospital, every Liver function index recovers normal value, cures.
Zhang, 60 years old, female, patient have weak, sitophobia, feel sick, the symptom such as abdominal distention, hepatalgia, examine through liver function index Surveying, be diagnosed as hepatitis B, take 4 courses for the treatment of of health product described in the embodiment of the present invention 5, check to hospital, every liver function refers to Mark recovers normal value, cures.
The present invention is not limited to above-mentioned preferred forms, and anyone can show that under the enlightenment of the present invention other are various The product of form, no matter but in its shape or structure, make any change, every have same as the present application or akin skill Art scheme, within all falling within protection scope of the present invention.

Claims (10)

1. one kind is used for the health product protected the liver, it is characterised in that raw material components includes:
Caulis et Folium Tritici aestivi extract 15-25 weight portion, Rhizoma amorphophalli 15-25 weight portion, yeast rich in selenium 2-8 weight portion, Pleurotus eryngii 15-25 weight Part, guar gum 15-25 weight portion, thunderbolt fruit 2-8 weight portion, Semen Castaneae 2-8 weight portion, Rhizoma Solani tuber osi 10-20 weight portion, Auricularia 10-20 weight portion, Fructus Lycii 10-20 weight portion, Folium Pini extract 5-15 weight portion, Rhizoma Phragmitis 5-15 weight portion.
Health product for protecting the liver the most according to claim 1, it is characterised in that raw material components includes: Caulis et Folium Tritici aestivi is extracted Thing 18-22 weight portion, Rhizoma amorphophalli 18-22 weight portion, yeast rich in selenium 4-6 weight portion, Pleurotus eryngii 18-22 weight portion, guar gum 18- 22 weight portions, thunderbolt fruit 4-6 weight portion, Semen Castaneae 4-6 weight portion, Rhizoma Solani tuber osi 12-16 weight portion, Auricularia 12-16 weight portion, Fructus Lycii Sub-12-16 weight portion, Folium Pini extract 8-12 weight portion, Rhizoma Phragmitis 8-12 weight portion.
3. the method for the health product for protecting the liver prepared described in claim 1 or 2, it is characterised in that include walking as follows Rapid:
(1) weigh described Pleurotus eryngii, Auricularia and Fructus Lycii, be dried respectively, after pulverization process, obtain the thin of each raw material Powder;Carry out the fine powder of described each raw material being sufficiently mixed uniformly, obtain the first mixed material;
(2) in described first mixed material, add 5-10 times of quality water to decoct, obtain decoction liquor;Described decoction liquor is depended on Secondary carrying out is filtered, concentrates, and obtains the first concentrate that relative density is 1.1-1.3g/ml, is done by described first concentrate Dry, pulverizing, obtains the first premix material, stand-by;
(3) weigh described Rhizoma amorphophalli, thunderbolt fruit, Semen Castaneae, Rhizoma Solani tuber osi and Rhizoma Phragmitis successively, be dried respectively, after pulverization process, obtain each The fine powder of raw material;The fine powder of described each raw material is sufficiently mixed, obtains the second mixed material;
(4) in described second mixed material, add the ethanol of 6-9 times of volume and 40-80 DEG C of reflux, extract, 1-2h, reclaim second Extracting solution is obtained after alcohol;Carry out described extracting solution successively filtering, concentrating, obtain that relative density is 1.2-1.4g/ml second Concentrate, is dried described second concentrate, pulverizes, and obtains the second premix material, stand-by;
(5) weigh described Caulis et Folium Tritici aestivi extract, yeast rich in selenium, guar gum and Folium Pini extract successively, be dried respectively, powder After broken process, obtain the fine powder of each raw material;The fine powder of described each raw material is sufficiently mixed, obtains the 3rd mixed material;
(6) in described 3rd mixed material, add the ethanol of 2-7 times of volume and 60-90 DEG C of reflux, extract, 1-4h, reclaim second Extracting solution is obtained after alcohol;Carry out described extracting solution successively filtering, concentrating, obtain that relative density is 1.3-1.6g/ml the 3rd Concentrate, is dried described 3rd concentrate, pulverizes, and obtains the 3rd premix material, stand-by;
(7) described for step (2) the first premix material, described second premix material of step (4) and step (6) the 3rd premix material are filled Point mix homogeneously, obtains described for the health product protected the liver.
Preparation method the most according to claim 3, it is characterised in that in step (1), the granularity of described each raw material fine powder is equal For 110-130 mesh.
Preparation method the most according to claim 3, it is characterised in that in step (2), described decoction repeats three times, The decoction liquor of three gained is merged;The time every time decocted is 30-60min;
In step (2), the temperature carrying out described concentration is 70-90 DEG C, carries out described dry temperature and is 110-130 DEG C, carries out The described dry time is 0.5-1.5h.
Preparation method the most according to claim 3, it is characterised in that in step (3), the granularity of the fine powder of described each raw material It is 80-110 mesh.
Preparation method the most according to claim 3, it is characterised in that in step (4), the volume fraction of the ethanol of addition is 85-95%;The temperature carrying out described concentration is 60-80 DEG C, carries out described dry temperature and is 100-120 DEG C, carries out described dry The dry time is 1-2h.
Preparation method the most according to claim 3, it is characterised in that in step (5), the granularity of the fine powder of described each raw material It is 120-150 mesh.
Preparation method the most according to claim 3, it is characterised in that in step (6), the volume fraction of the ethanol of addition is 75-85%;The temperature carrying out described concentration is 40-60 DEG C, carries out described dry temperature and is 80-100 DEG C, carries out described being dried Time be 2-4h.
10. the health product described in claim 1 or 2 are for preparing the application in food with effect of hepatic protection.
CN201610498274.7A 2016-06-29 2016-06-29 A kind of health product for protecting the liver and its preparation method and application Pending CN106072559A (en)

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