CN105999155A - Traditional Chinese medicine for treating thin endometrium - Google Patents
Traditional Chinese medicine for treating thin endometrium Download PDFInfo
- Publication number
- CN105999155A CN105999155A CN201610423601.2A CN201610423601A CN105999155A CN 105999155 A CN105999155 A CN 105999155A CN 201610423601 A CN201610423601 A CN 201610423601A CN 105999155 A CN105999155 A CN 105999155A
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- chinese medicine
- endometrium
- radix
- thin
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Abstract
The invention discloses traditional Chinese medicine for treating thin endometrium. The traditional Chinese medicine is mainly prepared from radix codonopsis, semen euryales, cornu cervi degelatinatum, fructus psoraleae, herba cistanches, rhizoma dioscoreae, pulp of cornus, radix salviae miltiorrhizae, caulis spatholobi, common ginger, trogopterus dung processed with wine and radix glycyrrhizae preparata. The formula composed of raw material medicine tonifies the kidney, activates blood, replenishes essence and cultivates cells, therefore, thickness of endometrium of females is enhanced, the menstrual blood volume is increased, capability of gestating babies of females is improved, and clinical treatment efficiency of the traditional Chinese medicine is 97.78%.
Description
Technical field
The present invention relates to a kind of treat the Chinese medicine that endometrium is thin, belong to technical field of Chinese medicines.
Background technology
Cyclic Human Endometrium thickness can reflect inner membrance functional status, and endometrium is sufficiently bred and turned with the inside secretory phase
Change is one of precondition of embryo's successful implantation.Measure endometrium thickness by B ultrasonic and can reflect intimal proliferation situation, be
Membrane stage essential condition in clinical judgment.Endometrium is thin is women common disease, it is considered that women have the most female
Under functions of hormones, when doing ultrasonic examination, endometrium can not reach the thickness of 8 millimeters to be judged as endometrium thin.
Endometrium is thin main and the age, history of artificial abortion, intrauterine surgical history, genital tuberculosis, the use of ART related drugs,
Inducing protocal, gene pleiomorphism etc. is relevant, and its mechanism predominantly estrogen receptor reduces, and damage causes endometrium reparation to hinder
Hinder.Clinically some patient to show as unknown cause endometrium thin, there are some researches show that possibility increases with endometrial blood flow resistance,
The down-regulated expression of VEGF, thus Endometrial blood flow reduces relevant.The common symptom that endometrium is thin has row
Menstrual period are short, hypomenorrhea or amenorrhea, color is light red, have dizziness and tinnitus concurrently, the symptom such as waist soreness, talalgia.
Medicine or other treatment measure are mainly taked in the treatment that endometrium is thin at present.Drug therapy is usually estrogen, low dosage
Aspirin, Combined Pentoxifylline vitamin E, sildenafil citrate, granular cell colony stimulating factor, growth hormone
Deng, generally there is side effect and untoward reaction in said medicine.Other treatment measure mainly includes imitative bioelectric stimulation, and stem cell is controlled
Treat.Said method still lacks a large amount of clinical trial certificate, needs further further investigated.Therefore treatment by Chinese herbs is because it is green, without secondary
Act on, control the advantages such as difficulty in relapse after healing, more and more paid attention to.
Summary of the invention
Instant invention overcomes above-mentioned the deficiencies in the prior art, it is provided that a kind of treat the Chinese medicine that endometrium is thin.This Chinese medicine is with 12
Taste Chinese prescription, invigorating kidney, promoting blood circulation, replenishing essence training born of the same parents, thus strengthen the endometrium thickness of women, increase menstrual blood volume, improve female
The ability breeding fetus of property.
The technical scheme is that and a kind of treat the Chinese medicine that endometrium is thin, it is characterized in that, mainly former by following weight parts
Material medicine is made: Radix Codonopsis 10～20 parts, Semen Euryales 10～20 parts, Cornu Cervi Degelatinatum 10～20 parts, Fructus Psoraleae 10～20 parts, Herba Cistanches
10～20 parts, Rhizoma Dioscoreae 20～30 parts, Fructus Corni 10～20 parts, Radix Salviae Miltiorrhizae 10～20 parts, Caulis Spatholobi 10～20 parts, Rhizoma Zingiberis Preparatum 5～
10 parts, wine Oletum Trogopterori 10～20 parts, Radix Glycyrrhizae Preparata 5～10 parts.
Optimum ratio: Radix Codonopsis 15 parts, Semen Euryales 15 parts, Cornu Cervi Degelatinatum 15 parts, Fructus Psoraleae 15 parts, Herba Cistanches 12 parts, Rhizoma Dioscoreae
24 parts, Fructus Corni 15 parts, Radix Salviae Miltiorrhizae 18 parts, Caulis Spatholobi 18 parts, Rhizoma Zingiberis Preparatum 6 parts, wine Oletum Trogopterori 15 parts, Radix Glycyrrhizae Preparata 6 parts.
If patient has a sleepless night, Radix Polygalae 6 parts, Arillus Longan 10 parts can be added on the basis of former side.
Preparation and instructions of taking: soak by water, every day 1 dose, take at twice sooner or later.
Above-mentioned raw materials medicine addition can also prepare various customary adjuvant required during different dosage form further, as excipient, correctives,
Binding agents etc. are prepared as any conventional oral formulations with conventional method of Chinese medicinal, as granule, pill, capsule,
Tablet, oral liquid etc..It is preferably granule.
Preferably, the preparation method of granule of the present invention is:
(1) Radix Codonopsis, Fructus Psoraleae, Herba Cistanches, Fructus Corni, Radix Salviae Miltiorrhizae and wine Oletum Trogopterori are added 70% alcohol heating reflux and extracts 2
Secondary, each 0.5～1 hour；United extraction liquid, after 200 eye mesh screens filter, adds heat extraction ethanol, obtains extracting solution；
(2) then by remaining 6 taste Chinese medicines (Semen Euryales, Cornu Cervi Degelatinatum, Rhizoma Dioscoreae, Caulis Spatholobi, Rhizoma Zingiberis Preparatum and Radix Glycyrrhizae Preparata) and step (1)
Medicinal residues merge, boiling 2 times, decoct 0.5～1.5 hour every time；Merge decoction liquor, after 200 eye mesh screens filter,
Obtain decoction liquor；
(3) extracting solution of combining step (1) and the decoction liquor of step (2), the heated relative density that is concentrated into is 1.20～1.30
The thick paste of (60 DEG C), is subsequently adding the cane sugar powder mix homogeneously of 1～3 times of quality, after (be suitably added during soft material processed through pelletizing
A small amount of 70% ethanol), be dried, screening after, be distributed into bag.
It is considered herein that: the thin traditional Chinese medical science " hypomenorrhea ", " infertile " category of belonging to of endometrium, "Fu Qingzhu works on obstetric" proposes
" go out all kidneys through water " " through this in kidney ", illustrate menstruation to need under the regulation of kidney and produce.Professor Luo Yuankai discusses the product of menstruation
During life, propose "-uterus is appointed in kidney-sky decyl-punching " Reproductive Axis, fill Sheng, whole body internal organs, gas what kidney qi, menses, punching were appointed
Blood, meridians mating reaction under, uterus periodically hides the result let out and produce.If kidney qi is weak, kidney qi thanks to exhausts, and menses is difficult to secrete
Extremely, rushing wantonly two arteries and veins and be difficult to fill Sheng, uterus loses supports, and the source of menses is deficient, then hypomenorrhea.Therefore inventors believe that this disease is treated
Palpus invigorating kidney, promoting blood circulation, replenishing essence training born of the same parents.
Side of the present invention solves as follows:
Monarch drug: Radix Codonopsis, Semen Euryales, Cornu Cervi Degelatinatum.Radix Codonopsis has strengthening spleen and tonifying lung, enriches blood, the effect promoted the production of body fluid.Semen Euryales kind energy supplementing the kidney to control the nocturnal,
And have the effect of spleen invigorating.Cornu Cervi Degelatinatum reinforcing the kidney and supporting YANG, has the property of convergence, has the merit of unsmoothing the sperm and stopping bleeding sore.Insufficiency of the spleen then QI and blood biochemistry is weary
Source, the then debility of CHONG and REN meridians of suffering from a deficiency of the kidney, three medicines are monarch drug altogether, kidney and spleen invigorating, then QI and blood foot, and punching is appointed solid.
Ministerial drug: Fructus Psoraleae, Herba Cistanches, Rhizoma Dioscoreae, Fructus Corni.Fructus Psoraleae has kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, warming spleen and stopping diarrha merit.
Herba Cistanches sweet in the mouth can be mended, and sweet temperature is supporing yang, and matter profit is nourished, salty to enter kidney, for kidney-replenishing, the good medicine of benefiting essence-blood.Rhizoma Dioscoreae has gas cloudy
Giving young employees remedial-courses in general knowledge and vocational skills, the dirty effect with benefit of spleen, lung, kidney three.Fructus Corni is warm in nature and the driest, mends and the highest, liver and kidney tonifying, can benefit essence, again
Can be supporing yang, for the key medicine of flat nourishing YIN sun.Said medicine tonifying liver spleen benefiting essence-blood, is ministerial drug altogether.The monarch and his subjects' phase 5, kidney tonifying, essence replenishing, temperature
Kidney is supporing yang.
Adjuvant drug: Radix Salviae Miltiorrhizae, Caulis Spatholobi, Rhizoma Zingiberis Preparatum, Oletum Trogopterori.Radix Salviae Miltiorrhizae promoting tissue regeneration by removing blood stasis and just do not hinder, stagnated blood, reinforcing the heart blood can be broken.Chicken
Caulis seu Radix Schisandrae Henryi is bitter and the driest, temperature and the strongest, promoting the circulation of blood dissipating blood stasis, menstruction regulating and pain relieving, character eases up, blood tonification effect of holding concurrently again.Rhizoma Zingiberis Preparatum has warming the meridian only
The merit of blood, " book on Chinese herbal medicine must be joined ": " Rhizoma Zingiberis Preparatum is kept and do not walked ... warming the liver warp, can go to dislike tissue regeneration promoting, make Yin grows while yang is generating ... ".Wine Oletum Trogopterori
There is promoting blood circulation and stopping pain, effect of removing stasis to stop bleeding.Medicine-feeding play blood circulation promoting and blood stasis dispelling altogether, go dislike tissue regeneration promoting effect, close " the kidney invigorating need to be invigorated blood circulation " it
Say, be adjuvant drug altogether.
Make medicine: Radix Glycyrrhizae Preparata coordinating the actions of various ingredients in a prescription.
Each raw material and effect
Radix Codonopsis: sweet in the mouth, property is flat, returns spleen, lung meridian, has strengthening spleen and tonifying lung, enriches blood, the effect promoted the production of body fluid." book on Chinese herbal medicine justice " meaning " is mended
Spleen nourishing the stomach, the lung moistening and production of body fluid promoting, gas in strong fortune, this is mutually the most remote with Radix Ginseng ".
Semen Euryales: Semen Euryales is sweet puckery, convergence, kind can supplementing the kidney to control the nocturnal, and have the effect of spleen invigorating, Shennong's Herbal say its " ... invigorating middle warmer,
Benefit vital essence ... ".
Cornu Cervi Degelatinatum: salty in the mouth, warm in nature, return liver, kidney channel.Function: reinforcing the kidney and supporting YANG, has the property of convergence, has unsmoothing the sperm and stopping bleeding sore
Merit.
Fructus Psoraleae: bitter in the mouth, pungent, warm in nature, return kidney, spleen channel.There are kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, warming spleen and stopping diarrha merit, " book on Chinese herbal medicine
Confucian classics " say: " Fructus Psoraleae, energy warming the kidney, raw sun in the moon, the key medicine of excessive fire benefit soil is also ".
Herba Cistanches: sweet in the mouth can be mended, and sweet temperature is supporing yang, matter profit is nourished, salty to enter kidney, for kidney-replenishing, the good medicine of benefiting essence-blood.
Rhizoma Dioscoreae: sweet in the mouth, property is put down.Having reinforcing both QI and YIN, the dirty effect with benefit of spleen, lung, kidney three, Shennong's Herbal says that it can " be mended
In, physical strength profiting, long muscle ".
Fructus Corni: Fructus Corni acid, tepor, matter profit, it is warm in nature and the driest, mends and the highest, liver and kidney tonifying, can benefit essence, again
Can be supporing yang, for the key medicine of flat nourishing YIN sun." property of medicine opinion " calls its " only the moon, water was indefinite, the kidney invigorating gas, Xing Yangdao, replenishing essence marrow ... ".
Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold, GUIXIN, pericardium, Liver Channel.Promoting tissue regeneration by removing blood stasis and just do not hinder, stagnated blood, reinforcing the heart blood can be broken." solar corona
Son book on Chinese herbal medicine " Yan Qineng " nourish blood sedate ... granulation promoting is put on flesh ... broken stagnated blood, mends new hemopoietic, peaceful tire, and fall stillborn fetus ... ".
Caulis Spatholobi: bitter in the mouth, micro-sweet, warm in nature, return Liver and kidney warp.Bitter and the driest, temperature and the strongest, promoting the circulation of blood dissipating blood stasis, menstruction regulating and pain relieving,
Character is eased up, blood tonification effect of holding concurrently again.
Rhizoma Zingiberis Preparatum: bitter, puckery, warm in nature.Return spleen, Liver Channel.There is the merit of warming the meridian for stopping bleeding, " book on Chinese herbal medicine must be joined ": " Rhizoma Zingiberis Preparatum is kept and is not walked ...
Warming the liver warp, can go to dislike tissue regeneration promoting, make Yin grows while yang is generating ... ".Rhizoma Zingiberis Preparatum is that Rhizoma Zingiberis is fried to surface duskiness, interior forms in brown color.
Wine Oletum Trogopterori: bitter, salty, sweet, warm in nature, return Liver Channel.There is promoting blood circulation and stopping pain, effect of removing stasis to stop bleeding.FAECES TROGOPTERORI with yellow rice wine: take
Clean Oletum Trogopterori is put in pot, heats with slow fire, fries to there being stink smell to overflow, when yellow skin is black, takes out immediately, uniformly sprays quantitatively while hot
Yellow wine, spreads out and dries.Oletum Trogopterori every 100kg yellow wine 15kg.
Radix Glycyrrhizae Preparata: sweet is flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: spleen reinforcing stomach function regulating, Yiqi and vein recovery.Empty for taste
Weak, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse, Radix Aconiti Lateralis Preparata poison can be solved.Radix Glycyrrhizae Preparata: extracting liquorice sheet, fries to yellow to deeply according to processed with honey method
Yellow, takes out time tack-free, dries in the air cool.
Full side plays the kidney invigorating and essence nourishing altogether, the effect of promoting blood circulation for tissue regeneration, then essence and blood foot, and born of the same parents can train, and tire is pregnant to be into.
The invention has the beneficial effects as follows: the present invention is with above-mentioned crude drug prescription, invigorating kidney, promoting blood circulation, replenishing essence training born of the same parents, thus strengthens women
Endometrium thickness, increase menstrual blood volume, improve the ability breeding fetus of women, its clinical treatment effective percentage is 97.78%.
Detailed description of the invention
Below in conjunction with clinical data and model case, its effect is described.
Embodiment 1
Formula (unit: g): Radix Codonopsis 15, Semen Euryales 15, Cornu Cervi Degelatinatum 15, Fructus Psoraleae 15, Herba Cistanches 12, Rhizoma Dioscoreae 24, mountain cornel
Meat 15, Radix Salviae Miltiorrhizae 18, Caulis Spatholobi 18, Rhizoma Zingiberis Preparatum 6, wine Oletum Trogopterori 15, Radix Glycyrrhizae Preparata 6.
Preparation and instructions of taking: soak by water, every day 1 dose, take at twice sooner or later.
Below in conjunction with clinical data and model case, its effect is described.
1. clinical data
Choosing the first visit time is 2014 01 month to 2015 01 month, my institute's Out-patient Clinic of Department of Gynecology endometrium thin patient 89 example, suffers from
Person's disease sees Hypomenorrhea or amenorrhea, light through color, and soreness of the waist and knees is infertile, light red tongue, white and thin fur, deep-thready pulse.It is randomly divided into observation
Organizing 45 examples, in age 24-48 year, the course of disease 2 months to 20 years, average 5.24 ± 3.33 years, advanced age 15, example, had artificial abortion
History 27 example, intrauterine surgical history 30 example, genital tuberculosis history 10 example.Matched group 44 example, age 23-49 year, the course of disease 3
The moon, average 5.54 ± 5.0 years, advanced age 14, example, had history of artificial abortion 25 example, intrauterine surgical history 28 example, genitals to 20 years
Tuberculosis history 10 example.
2. method
2.1 Therapeutic Method
Matched group: oral progynova, every day 1 time, each 1mg, serve on 6 months.Observation group is administered orally Chinese medicine of the present invention, often
Day potion, point takes for twice sooner or later, takes 6 months.If patient fully recovers in advance during this period, i.e. withdrawal, the longest treatment
Time is 6 months.Continue after two groups of drug withdrawals to observe 6 months.
2.2. observation index
(1) before and after observing treatment, menstrual blood volume improves situation: menstrual blood volume how much criterion is with reference to artificial satellite's version clinic high medical education teaching material
8th edition " obstetrics and gynecology ".
(2) endometrium thickness change before and after treatment is observed；
(3) record untoward reaction.
2.3 statistical method
All data SPSS12.0for windows software kits carry out x2Inspection.
3 results
3.1 recoveries from illness: menstrual blood volume has recovered normal, endometrium thickness is recovered normally, and other clinical symptoms thoroughly disappear, and stop
Through amount without reducing after medicine.Effective: hyper-menorrhea 1/3rd, or menstrual blood volume is more than 20ml, endometrium thickness increase but not
Reaching normal, other clinical symptoms disappear substantially.Effective: menstrual blood volume increases the most a little, endometrium thickness is slightly improved,
Other clinical symptoms make moderate progress, and in drug withdrawal 3 months, symptom does not increases the weight of.Invalid: endometrium thickness is without improving or thinner, main
Wanting symptom unchanged or deteriorate, localized variation has and increases the weight of trend.
3.2 liang of group Clinical efficacy comparisons
Two groups of patient clinical comparitive study the results are shown in Table 1.
1 liang of table group patient clinical comparitive study [n (%)]
| Group | n | Recovery from illness | Effective | Effectively | Invalid | Total effective rate |
| Observation group | 45 | 12(26.67) | 18(40) | 14(31.11) | 1(2.22) | 97.78% |
| Matched group | 44 | 4(9.09) | 16(36.36) | 12(27.27) | 12(27.27) | 72.73% |
P ＜ 0.05 is compared with matched group.
Before and after 3.3 liang of group treatments, menstrual blood volume improves situation
Before and after patient's (except amenorrhea patients) treatment, the therapeutic outcome of menstrual blood volume change is shown in Table 2.
Before and after 2 liang of table group patient treatment, menstrual blood volume improves situation (n)
P ＜ 0.05 is compared with matched group.
3.4 untoward reaction
There are 13 example untoward reaction in matched group, and incidence rate is 29.55%, and observation group has no adverse reaction.
3.5 follow up a case by regular visits to recurrence
Following up a case by regular visits to after drug withdrawal 6 months, 5 examples are recurred in observation group, and relapse rate is 11.11%.Matched group recurs 23 examples, relapse rate 52.27%.
It can thus be seen that the thin determined curative effect for the treatment of by Chinese herbs endometrium (total effective rate 97.78%) of the present invention, have no side effect, more after
Relapse rate is extremely low.
Two, model case
Model case 1: Lee, female is 24 years old, unmarried.
December in 2015 first visit on the 20th.Readme Hypomenorrhea more than 10 years, exacerbation of symptoms in this year, menstrual blood volume is the most obvious
Reducing, 2 days the cleanest.Disease is seen: 14 years old 2-3/30-35 days, Hypomenorrhea, and the light matter of color is dilute, painless warp, lassitude loin and legs, dizzy
Tinnitus, complexion is dark dim, and light red tongue is dim, white and thin fur, deep-thready pulse.LMP:2015 December 1 day.G0.B ultrasonic prompting uterus
And double accessory district shows no obvious abnormalities, interior thickness 0.5cm.Being diagnosed as hypomenorrhea, card belongs to deficiency of kidney-essence, controls suitable kidney tonifying, essence replenishing.
Give the prescription therapeutic of embodiments of the invention 1, be decocted in water for oral dose, potion on the one, divides and sooner or later takes for twice.
Two examine: on January 1st, 2016.Stating this menstrual blood volume to increase earlier above, soreness of the waist and knees, the symptom such as dizziness and tinnitus substantially alleviates.
Immediate cause operating pressure is big, insomnia occurs.Then on the basis of former side, Radix Polygalae 6g, Arillus Longan 10g are added.
Three examine: on February 3rd, 2016.Stating this menstrual blood volume showed increased earlier above, color is scarlet, matter can, soreness of the waist and knees, dizzy
The symptoms such as tinnitus disappear substantially, and sleep quality is obviously improved, and endometrium thickness recovers normal.The prescription of embodiment 1 is with 10 doses
To consolidate curative effect.
Follow up a case by regular visits to so far, hyper-menorrhea, 5-6 days are clean, chromaticness can, painless warp and other are uncomfortable.
Model case 2: slowly certain, female, 30 years old, married.
First visit on January 5 in 2016.Because peritubal adhesions is in Hospital in Shandong row IVF, the thin cancellation of postfactor Endometrium
This cycle transplants, previously 2 history of artificial abortion, 1 history of medical abortion.Menstruation rule, 14 years old 3/28-30 days, amount was few, color
Light, matter can, slight dysmenorrhea, fear cold limb cool, clear urine in large amounts, light red tongue, tongue is white, thready pulse.LMP:2015 December 20 days.
G3A3.Gynecologial examination: pudendum is grown normal, and vagina is unobstructed, and cervix uteri is smooth, uterus normal in size, without tenderness, double accessory district
No abnormality seen.B ultrasonic prompting uterus and double accessory district show no obvious abnormalities, interior thickness 0.6cm.Card belongs to insufficiency of kidney-YANG, controls suitable the kidney invigorating
Supporing yang, replenishing essence training born of the same parents.Give the prescription therapeutic of embodiments of the invention 1, be decocted in water for oral dose, potion on the one, divides and sooner or later takes for twice.
Two examine: on February 5th, 2016.State hyper-menorrhea, be afraid of cold, the symptom such as clear urine in large amounts alleviates, remaining without uncomfortable.B ultrasonic
Show endometrium 0.8cm.Continue with 14 doses in top.
Three examine: on February 19th, 2016.Menstrual blood volume showed increased, is afraid of cold, the transference cure such as clear urine in large amounts, without uncomfortable.B
Surpass and show endometrium 1.0cm.Continue with 14 doses in top.
Follow up a case by regular visits to so far, successful pregnancies after graft.
Model case 3: Zheng, female is 29 years old, married.
First visit on January 1 in 2016.Marry more than 1 year, do not practise contraception unpregnancy so far, delayed menstrual cycle, 16 years old 2-3/40-45 days,
Amount is few, and color is light, and leucorrhea amount is many at ordinary times, and the cold limb of abdomen is trembled with fear, and libido is indifferent, and complexion is dark dim, light red tongue, white, slippery and moist fur, deep-thready pulse.LMP:
On December 31st, 2015.G0.In October, 2015 is shown in the court row HSG: bilateral salpingo is unobstructed.Gynecologial examination: outer
Cloudy growth is normal, and vagina is unobstructed, and cervix uteri is smooth, uterus normal in size, without tenderness, double accessory district no abnormality seen.B ultrasonic is pointed out
Uterus and double accessory district show no obvious abnormalities, interior thickness 0.4cm.Being diagnosed as insufficiency of kidney-YANG infertility, card belongs to insufficiency of kidney-YANG, controls preferably
Reinforcing the kidney and supporting YANG, replenishing essence training born of the same parents.Give the prescription therapeutic of embodiments of the invention 1, be decocted in water for oral dose, potion on the one, point morning and evening twice
Take.Non-medication in menstrual period.
Two examine: on January 15th, 2016.Stating leucorrhea to reduce earlier above, symptom of being afraid of cold substantially alleviates, and the same branch of a family quality is improved,
Light red tongue, tongue is white, thready pulse.B ultrasonic shows inner membrance 0.7cm.Top is continued with 20 doses, B ultrasonic dynamic monitoring endometrium thickness and follicle
Growth promoter situation, and guides the same branch of a family.
Three examine: on February 4th, 2016.Stating menstrual blood volume showed increased earlier above, color is scarlet, and the cold limb of abdomen is trembled with fear, the symptoms such as libido is indifferent
Disappear, without uncomfortable.Continue with 20 doses to consolidate curative effect in top, B ultrasonic dynamic monitoring endometrium thickness and Follicular growth situation,
And guide the same branch of a family.
The four diagnostic methods: on April 1st, 2016.Test oneself urine HCG+, have a blood test and show: E2:325P:35 β HCG:6000.
B ultrasonic shows: visit and gestation sac 1.20 × 0.80 × 0.70cm in uterine cavity.Visit and yolk sac, do not visit and tire bud.Ultrasonic diagnosis: early pregnancy
(meeting 5+ pregnant week).
Following up a case by regular visits to so far, fetal development is normal.
Embodiment 2
Formula (unit: g): Radix Codonopsis 18, Semen Euryales 18, Cornu Cervi Degelatinatum 18, Fructus Psoraleae 18, Herba Cistanches 12, Rhizoma Dioscoreae 25, mountain cornel
Meat 18, Radix Salviae Miltiorrhizae 20, Caulis Spatholobi 20, Rhizoma Zingiberis Preparatum 8, wine Oletum Trogopterori 18, Radix Glycyrrhizae Preparata 8.
Preparation and instructions of taking: soak by water, every day 1 dose, take at twice sooner or later.
Embodiment 3
Formula (unit: g): Radix Codonopsis 12, Semen Euryales 12, Cornu Cervi Degelatinatum 12, Fructus Psoraleae 12, Herba Cistanches 10, Rhizoma Dioscoreae 22, mountain cornel
Meat 12, Radix Salviae Miltiorrhizae 15, Caulis Spatholobi 15, Rhizoma Zingiberis Preparatum 5, wine Oletum Trogopterori 12, Radix Glycyrrhizae Preparata.
Preparation and instructions of taking: soak by water, every day 1 dose, take at twice sooner or later.
Embodiment 4
Formula (weight portion): Radix Codonopsis 15, Semen Euryales 15, Cornu Cervi Degelatinatum 15, Fructus Psoraleae 15, Herba Cistanches 12, Rhizoma Dioscoreae 24, mountain cornel
Meat 15, Radix Salviae Miltiorrhizae 18, Caulis Spatholobi 18, Rhizoma Zingiberis Preparatum 6, wine Oletum Trogopterori 15, Radix Glycyrrhizae Preparata 6.
Preparation method:
(1) Radix Codonopsis, Fructus Psoraleae, Herba Cistanches, Fructus Corni, Radix Salviae Miltiorrhizae and wine Oletum Trogopterori are added 70% alcohol heating reflux and extracts 2
Secondary, each 40 minutes；United extraction liquid, after 200 eye mesh screens filter, adds heat extraction ethanol, obtains extracting solution；
(2) then by remaining 6 taste Chinese medicines (Semen Euryales, Cornu Cervi Degelatinatum, Rhizoma Dioscoreae, Caulis Spatholobi, Rhizoma Zingiberis Preparatum and Radix Glycyrrhizae Preparata) and step (1)
Medicinal residues merge, boiling 2 times, decoct 40 minutes every time；Merge decoction liquor, after 200 eye mesh screens filter, decocted
Boil liquid；
(3) extracting solution of combining step (1) and the decoction liquor of step (2), the heated relative density that is concentrated into is 1.25 (60 DEG C)
Thick paste, be subsequently adding the cane sugar powder mix homogeneously of 2 times of quality, be subsequently adding a small amount of 70% ethanol and make soft material, cross 14 mesh Buddhist nuns
Dragon sieve series grain；After wet grain drying, after sieve, retain the granule of 14-50 mesh, be then distributed into 10g every bag.
Instructions of taking: warm water is taken after mixing it with water, three times a day, one time 1 bag, within 30～60 minutes after meal, take.
Claims (7)
1. treat the Chinese medicine that endometrium is thin, it is characterized in that, be mainly made up of the crude drug of following weight parts: Radix Codonopsis 10～
20 parts, Semen Euryales 10～20 parts, Cornu Cervi Degelatinatum 10～20 parts, Fructus Psoraleae 10～20 parts, Herba Cistanches 10～20 parts, Rhizoma Dioscoreae 20～
30 parts, Fructus Corni 10～20 parts, Radix Salviae Miltiorrhizae 10～20 parts, Caulis Spatholobi 10～20 parts, Rhizoma Zingiberis Preparatum 5～10 parts, wine Oletum Trogopterori 10～
20 parts, Radix Glycyrrhizae Preparata 5～10 parts.
A kind of treat the Chinese medicine that endometrium is thin, it is characterized in that, mainly former by following weight parts
Material medicine is made: Radix Codonopsis 15 parts, Semen Euryales 15 parts, Cornu Cervi Degelatinatum 15 parts, Fructus Psoraleae 15 parts, Herba Cistanches 12 parts, Rhizoma Dioscoreae 24 parts,
Fructus Corni 15 parts, Radix Salviae Miltiorrhizae 18 parts, Caulis Spatholobi 18 parts, Rhizoma Zingiberis Preparatum 6 parts, wine Oletum Trogopterori 15 parts, Radix Glycyrrhizae Preparata 6 parts.
A kind of treat the Chinese medicine that endometrium is thin, it is characterized in that, by the crude drug of following weight parts
Make: Radix Codonopsis 15 parts, Semen Euryales 15 parts, Cornu Cervi Degelatinatum 15 parts, Fructus Psoraleae 15 parts, Herba Cistanches 12 parts, Rhizoma Dioscoreae 24 parts, mountain
Fructus Corni 15 parts, Radix Salviae Miltiorrhizae 18 parts, Caulis Spatholobi 18 parts, Rhizoma Zingiberis Preparatum 6 parts, wine Oletum Trogopterori 15 parts, Radix Glycyrrhizae Preparata 6 parts.
A kind of treat the Chinese medicine that endometrium is thin, it is characterized in that, by the crude drug of following weight parts
Make: Radix Codonopsis 15 parts, Semen Euryales 15 parts, Cornu Cervi Degelatinatum 15 parts, Fructus Psoraleae 15 parts, Herba Cistanches 12 parts, Rhizoma Dioscoreae 24 parts, mountain
Fructus Corni 15 parts, Radix Salviae Miltiorrhizae 18 parts, Caulis Spatholobi 18 parts, Rhizoma Zingiberis Preparatum 6 parts, wine Oletum Trogopterori 15 parts, Radix Glycyrrhizae Preparata 6 parts, Radix Polygalae 6 parts,
Arillus Longan 10 parts.
5. a kind of as described in any one in claim 1-4 treats the Chinese medicine that endometrium is thin, it is characterized in that, described Chinese medicine
For granule, pill, capsule, tablet, oral liquid.
A kind for the treatment of the Chinese medicine that endometrium is thin, it is characterized in that, described Chinese medicine is granule.
7. a kind of preparation method treating the thin Chinese medicine of endometrium described in claim 6, is characterized in that,
(1) Radix Codonopsis, Fructus Psoraleae, Herba Cistanches, Fructus Corni, Radix Salviae Miltiorrhizae and wine Oletum Trogopterori are added 70% alcohol heating reflux and extracts 2
Secondary, each 0.5～1 hour；United extraction liquid, after 200 eye mesh screens filter, adds heat extraction ethanol, obtains extracting solution；
(2) then the medicinal residues of remaining 6 taste Chinese medicines and step (1) are merged, boiling 2 times, decoct 0.5～1.5 every time
Hour；Merge decoction liquor, after 200 eye mesh screens filter, obtain decoction liquor；
(3) extracting solution of combining step (1) and the decoction liquor of step (2), heated when being concentrated into 60 DEG C relative density be
The thick paste of 1.20～1.30, is subsequently adding the cane sugar powder mix homogeneously of 1～3 times of quality, after through pelletizing, being dried, after screening,
It is distributed into bag.
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| CN107334900A (en) * | 2017-06-09 | 2017-11-10 | 王孟 | It is a kind of to treat thin infertile and amenorrhoea medicament of cause of endometrium and preparation method thereof |
| RU2655538C1 (en) * | 2017-07-17 | 2018-05-28 | федеральное государственное бюджетное образовательное учреждение высшего образования "Приволжский исследовательский медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО "ПИМУ" Минздрава России) | Method of endometrial dysfunction treatment |
| CN112426502A (en) * | 2020-12-11 | 2021-03-02 | 山东宏济堂制药集团股份有限公司 | Application of young chicken essence in treating thin endometrium |
| CN113018367A (en) * | 2021-03-16 | 2021-06-25 | 南京中医药大学 | Traditional Chinese medicine composition for treating thin endometrial hypomenorrhea and preparation method and application thereof |
| CN117860842A (en) * | 2024-03-13 | 2024-04-12 | 云南省中医医院(云南中医药大学第一附属医院) | Acupoint plaster for endometrial repair, and preparation method and application thereof |
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| CN107334900A (en) * | 2017-06-09 | 2017-11-10 | 王孟 | It is a kind of to treat thin infertile and amenorrhoea medicament of cause of endometrium and preparation method thereof |
| RU2655538C1 (en) * | 2017-07-17 | 2018-05-28 | федеральное государственное бюджетное образовательное учреждение высшего образования "Приволжский исследовательский медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО "ПИМУ" Минздрава России) | Method of endometrial dysfunction treatment |
| CN112426502A (en) * | 2020-12-11 | 2021-03-02 | 山东宏济堂制药集团股份有限公司 | Application of young chicken essence in treating thin endometrium |
| CN113018367A (en) * | 2021-03-16 | 2021-06-25 | 南京中医药大学 | Traditional Chinese medicine composition for treating thin endometrial hypomenorrhea and preparation method and application thereof |
| CN113018367B (en) * | 2021-03-16 | 2022-03-25 | 南京中医药大学 | Traditional Chinese medicine composition for treating thin endometrial hypomenorrhea and preparation method and application thereof |
| CN117860842A (en) * | 2024-03-13 | 2024-04-12 | 云南省中医医院(云南中医药大学第一附属医院) | Acupoint plaster for endometrial repair, and preparation method and application thereof |
| CN117860842B (en) * | 2024-03-13 | 2024-05-28 | 云南省中医医院(云南中医药大学第一附属医院) | Acupoint patch for endometrial repair and application thereof |
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