CN104147559A - Traditional Chinese medicine preparation for treating gynecological endometritis - Google Patents
Traditional Chinese medicine preparation for treating gynecological endometritis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating gynecological endometritis. The traditional Chinese medicine preparation is prepared from the following medicinal raw materials in parts by weight: 25-30 parts of dayflower, 5-8 parts of astragalus, 3-5 parts of cyperus rotundus, 3-5 parts of cistanche, 3-5 parts of raspberry, 25-30 parts of angelica sinensis, 25-30 parts of poria cocos, 25-30 parts of white paeony root, 20-30 parts of motherwort, 20-25 parts of dendrobe, 5-8 parts of Chinese ladiestresses root or herb, 5-8 parts of rhizoma corydalis, 1-5 parts of rhizome of rehmannia, 1-5 parts of rhizoma atractylodis, 8-12 parts of rhizoma zingiberis, 1-5 parts of ligusticum wallichii, 1-5 parts of sargentgloryvine stem, 1-5 parts of the seed of Chinese dodder, 1-3 parts of honeysuckle stem, 1-3 parts of corydalis tuber, 3-5 parts of solanum lyratum, 3-5 parts of Chinese violet, 3-5 parts of honeysuckle, 3-8 parts of Houttuynia cordata, 8-12 parts of moutan bark, 8-12 parts of radix fici simplicissimae and 8-12 parts of Licorice Roots Northwest Origin. The traditional Chinese medicine preparation is used for effectively treating the endometritis, has a good effect of preventing the endometritis, does not have any toxic or side effect and is convenient to take.
Description
Technical field
The present invention relates to Chinese medicine preparation technical field, relate in particular to a kind of Chinese medicine preparation for the treatment of gynecological's endometritis.
Background technology
Endometritis is that the endometrium structure generation inflammatory that a variety of causes causes changes.Uterine cavity has good drain condition and Endarterectomy periodically, makes the few chance of inflammation stay in for a long time endometrium, but as acute stage inflammation treatment not thorough, or often there is the source of infection, can repeatedly show effect.Chronic endometritis is the common cause that causes miscarriage.The clinical symptoms of endometritis mainly contains: (1) pelvic cavity region pain: occur that at menstruation tempus intercalare hypogastric region falling pain and lumbosacral region ache.(2) leucorrhoea grow in quantity: due to inner membrance glandular secretion increase.Be generally thin water sample, faint yellow, be sanguinous leukorrhea sometimes.Senile endometrium inflammation is purulent leukorrhea, and often containing a small amount of blood.In the time of pyometra, secretions is purulence companion stink.(3) menorrhagia: menstrual period rule and through blood volume multiplication, the phase significant prolongation of bleeding.Irregular bleeding is more rare.(4) dysmenorrhea: be more common in nullipara female, but serious dysmenorrhea person is rare, may excessively thicken due to inner membrance, hinders and organizes normal regression necrosis, stimulates due to the excessive spastic contraction in uterus.
At present, the mode of clinical drug therapy mainly contains: (1) palace intracavitary administration: the mode that can adopt palace intracavitary administration to married patient, before operation, first investigate thoroughly uterus size and location with bimanual examination, after vulvovaginal sterilization, the detection uterine cavity degree of depth, sterilizing catheter is sent into uterine cavity from palace mouth, to be less than uterine cavity degree of depth 0.5cm, by selected medicine, slowly inject uterine cavity through catheter, all enter after uterine cavity until medicinal liquid, extract catheter, flat sleeping or high l～2 hour of buttocks, every day 1 time, stop using menstrual period, makes medicine directly act on affected area.(2) antibiotic therapy clear up uterine cavity: betide childbirth or postabortal endometritis, as it is residual to be suspected to have placenta tissue, should using the antibiotic while, removed immediately, in the time that antibiotic reaches doses, inflammation and is controlled, can the row dilatation and curettage, in case inflammation diffusion.If when there is active hemorrhage in uterus, can in a large amount of antibiotic situations of application, clear up uterine cavity.
Said medicine drug treatment mode is comparatively complicated, takes effect slow and can not reach the object for the treatment of both the principal and secondary aspects of a disease, and curative effect has much room for improvement.
Summary of the invention
The object of the invention is for the deficiencies in the prior art provide that one is taken simply, instant effect, good effect, and can reach the Chinese medicine preparation of the treatment gynecological endometritis of the object for the treatment of both the principal and secondary aspects of a disease.
The object of the invention is provides a kind of preparation method simply to treat the preparation method of the Chinese medicine preparation of gynecological's endometritis for the deficiencies in the prior art.
The present invention is achieved through the following technical solutions.
A kind of Chinese medicine preparation for the treatment of gynecological's endometritis, it is characterized in that: by weight, it comprises the medicinal raw material of following weight portion: Herba Commelinae 25-30 part, Radix Astragali 5-8 part, Rhizoma Cyperi 3-5 part, Herba Cistanches 3-5 part, Fructus Rubi 3-5 part, Radix Angelicae Sinensis 25-30 part, Poria 25-30 part, Radix Paeoniae Alba 25-30 part, Herba Leonuri 20-30 part, Herba Dendrobii 20-25 part, Radix seu Herba Spiranthis Lanceae 5-8 part, Rhizoma Corydalis 5-8 part, Radix Rehmanniae 1-5 part, Rhizoma Atractylodis 1-5 part, Rhizoma Zingiberis 8-12 part, Rhizoma Chuanxiong 1-5 part, Caulis Sargentodoxae 1-5 part, Semen Cuscutae 1-5 part, Caulis Lonicerae 1-3 part, Rhizoma Corydalis 1-3 part, Herba Solani Lyrati 3-5 part, Herba Violae 3-5 part, Flos Lonicerae 3-5 part, Herba Houttuyniae 3-8 part, Cortex Moutan 8-12 part, Herba Fici Simplicissimae 8-12 part, Radix Glycyrrhizae 8-12 part.
Wherein, by weight, it comprises the medicinal raw material of following weight portion: Herba Commelinae 25-27 part, Radix Astragali 7-8 part, Rhizoma Cyperi 3-4 part, Herba Cistanches 4-5 part, Fructus Rubi 3-4 part, Radix Angelicae Sinensis 25-27 part, Poria 28-30 part, Radix Paeoniae Alba 25-26 part, Herba Leonuri 25-30 part, Herba Dendrobii 20-22 part, Radix seu Herba Spiranthis Lanceae 5-6 part, Rhizoma Corydalis 7-8 part, Radix Rehmanniae 1-3 part, Rhizoma Atractylodis 1-3 part, Rhizoma Zingiberis 8-10 part, Rhizoma Chuanxiong 1-3 part, Caulis Sargentodoxae 3-5 part, Semen Cuscutae 1-3 part, Caulis Lonicerae 1-2 part, Rhizoma Corydalis 1-2 part, Herba Solani Lyrati 3-4 part, Herba Violae 4-5 part, Flos Lonicerae 4-5 part, Herba Houttuyniae 6-8 part, Cortex Moutan 11-12 part, Herba Fici Simplicissimae 8-10 part, Radix Glycyrrhizae 8-9 part.
Wherein, by weight, it comprises the medicinal raw material of following weight portion: Herba Commelinae 28-30 part, Radix Astragali 5-6 part, Rhizoma Cyperi 4-5 part, Herba Cistanches 3-4 part, Fructus Rubi 4-5 part, Radix Angelicae Sinensis 28-30 part, Poria 25-27 part, Radix Paeoniae Alba 27-30 part, Herba Leonuri 20-25 part, Herba Dendrobii 23-25 part, Radix seu Herba Spiranthis Lanceae 7-8 part, Rhizoma Corydalis 5-6 part, Radix Rehmanniae 4-5 part, Rhizoma Atractylodis 4-5 part, Rhizoma Zingiberis 10-12 part, Rhizoma Chuanxiong 4-5 part, Caulis Sargentodoxae 1-2 part, Semen Cuscutae 4-5 part, Caulis Lonicerae 2-3 part, Rhizoma Corydalis 2-3 part, Herba Solani Lyrati 4-5 part, Herba Violae 3-4 part, Flos Lonicerae 3-4 part, Herba Houttuyniae 3-5 part, Cortex Moutan 8-10 part, Herba Fici Simplicissimae 11-12 part, Radix Glycyrrhizae 10-12 part.
Preferably, by weight, it comprises the medicinal raw material of following weight portion: Herba Commelinae 27-29 part, Radix Astragali 6-7 part, Rhizoma Cyperi 4-5 part, Herba Cistanches 3-4 part, Fructus Rubi 3-4 part, Radix Angelicae Sinensis 27-29 part, Poria 27-29 part, Radix Paeoniae Alba 26-28 part, Herba Leonuri 23-26 part, Herba Dendrobii 22-24 part, Radix seu Herba Spiranthis Lanceae 6-7 part, Rhizoma Corydalis 6-7 part, Radix Rehmanniae 3-4 part, Rhizoma Atractylodis 2-3 part, Rhizoma Zingiberis 9-10 part, Rhizoma Chuanxiong 3-4 part, Caulis Sargentodoxae 2-4 part, Semen Cuscutae 3-4 part, Caulis Lonicerae 2-3 part, Rhizoma Corydalis 2-3 part, Herba Solani Lyrati 3-4 part, Herba Violae 3-4 part, Flos Lonicerae 4-5 part, Herba Houttuyniae 5-7 part, Cortex Moutan 9-10 part, Herba Fici Simplicissimae 9-10 part, Radix Glycyrrhizae 9-10 part.
Further, by weight, also comprise the Herba Lycopi of 1-5 weight portion and the Herba Taraxaci of 1-5 weight portion.
Further, by weight, also comprise the Radix Salviae Miltiorrhizae of 3-8 weight portion.
Further, by weight, it also comprises the Radix Picriae felterrae of 1-5 weight portion.
Further, by weight, it also comprises the Cortex Cinnamomi of 10-15 weight portion.
Herba Commelinae sweet in the mouth, micro-hardship, cold in nature.Energy heat clearing away, removing toxic substances, diuresis.For the good medicine of swelling diuretic, heat-clearing and toxic substances removing, in addition to hordeolum, pharyngitis, tonsillitis, cervical erosion, the Agkistrodon halys good efficacy of having bitten.Function cures mainly: row water, heat clearing away, removing heat from blood, removing toxic substances.Harness the river swollen, beriberi, dysuria, flu, erysipelas, parotitis, icterohepatitis, hematodiarrhoea, malaria, epistaxis, hematuria, metrorrhagia, leucorrhea, laryngopharynx swelling and pain, carbuncle furuncle.
The medicinal history of existing more than 2000 year so far of the Radix Astragali, it has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
The Rhizoma Cyperi resolving depression of regulating the flow of vital energy; Menstruction regulating and pain relieving; Antiabortive.Main distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.Kidney-replenishing; Benefiting essence-blood; Intestine moistening road.
The main kidney yang deficiency of Herba Cistanches; The sexual impotence of asthenia of essence and blood; Seminal emission; Nebulousurine; The frequent micturition heeltap; Lumbago flaccidity of the lower limbs; Tinnitus order flower; Menstruation is spread out the phase; Infertility; Dryness of the intestine constipation.
Fructus Rubi invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, improving eyesight, impotence and premature ejaculation, emission and spermatorrhea, cold womb is infertile, and leukorrhagia is rare clearly, frequent micturition incontinence of urine, blurred vision is dark, early whitening of beard and hair.
Radix Angelicae Sinensis sweet in the mouth; Pungent; Bitter; Warm in nature, return liver; The heart; Spleen channel, has and enriches blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize effect of laxation, can be used for all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.Radix Angelicae Sinensis regulates the effect of body's immunity, cosmetology effect, the effect of invigorating blood circulation of enriching blood, antibacterial, arteriosclerosis effect.Radix Angelicae Sinensis all has antibacterial action to external dysentery, typhoid fever, paratyphoid fever, escherichia coli, diphtheria corynebacterium, vibrio cholera and A, B Hemolytic streptococcus etc.External can be accelerated rabbit ear wound healing, and contrafluxion, leukocyte and fiber are infiltrated, and newborn epithelium regeneration has hemostasis and strengthens peripheral circulation effect local organization.Illustrate that Radix Angelicae Sinensis has antibacterial, antiinflammation.
Poria meridian distribution of property and flavor: sweet, light, flat.GUIXIN, spleen, kidney channel.Poria has promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, the anticancer effect that relieves internal heat, and the property of medicine is gentle, dampness removing and do not hinder healthy energy, can control dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, the disease such as forgetful.Contained pachymic acid has enhancing immunity, prevents hepatic necrosis, the effect such as antibacterial.In addition, the main component in Poria is pachyman, and content is very high, and various bacteria is had to inhibitory action; Can many-sided immunologic function be regulated.
The Radix Paeoniae Alba is cool in nature, and bitter in the mouth acid, is slightly cold, and has the easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing is received the effect such as antiperspirant, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction anxious, dysentery stomachache, spontaneous sweating, metrorrhagia, is with inferior disease.That paeoniflorin has is antibacterial, antipyretic, antiinflammatory, increase coronary flow, improve the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjusting blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.
Herba Leonuri enters the heart, liver, urinary bladder channel, have invigorate blood circulation, effect of blood stasis dispelling, regulating menstruation, the water that disappears.Cure mainly and control menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Herba Leonuri decoct, water logging or ethanol extract and Herba Leonuri total alkali all have excitation to the uterus of the many animals such as Cavia porcellus, rabbit, cat, dog.Experimental results show that: Herba Leonuri decoct, to unpregnancy, early pregnancy, late pregnancy or isolated rabbit in puerperal uterus, all has excitation.Herba Leonuri infusion (1: 4) to being permitted the skin pathogenicity funguses such as blue achorion, ulotrichy microspore's tinea bacterium, epidermophyton rubrum, star-shaped nocardia, all has inhibitory action in various degree in vitro.
Herba Dendrobii reinforcing stomach reg fluid, nourishing YIN and clearing away heat, Herba Dendrobii has the function of nourishing YIN and benefiting blood, can the kidney invigorating amass essence, nourishing stomach-YIN, physical strength profiting; Replenishing YIN and removing heat, reinforcing stomach reg fluid.Cure mainly cloudy impairment of body fluid and lose, xerostomia excessive thirst, lack of appetite is retched, burning pain in the epigastrium, the order of suffering from a deficiency of the kidney is dark, visual deterioration, cataract is blind, the flaccidity syndrome and arthralgia syndrome of suffering from a deficiency of the kidney, waist foot weakness.In Herba Dendrobii, contain and have abundant polysaccharose substance.Experimental results show that dendrobium polysaccharide has the effect that strengthens immunologic function, can strengthen the phagocytic activity of peritoneal macrophage to chicken red blood cell.
Radix seu Herba Spiranthis Lanceae nature and flavor: sweetness and bitterness, flat.Function cures mainly: tonifying YIN heat clearing away, nourishing the lung to arrest cough.Weak after curing the disease, yin asthenia generating intrinsic heat, cough is spitted blood, dizziness, the soreness of waist, seminal emission, stranguria with turbid discharge leukorrhagia, skin infection carbuncle.
Rhizoma Corydalis is warm in nature, and acrid in the mouth hardship enters the heart, spleen, liver, lung, is the quality goods of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, is especially world-famous for effect of pain relieving.Li Shizhen (1518-1593 A.D.) is concluded Rhizoma Corydalis in Compendium of Material Medica " invigorate blood circulation, regulate the flow of vital energy, pain relieving, diuresis " four large effects, and praises highly Rhizoma Corydalis " stagnation of QI in energy promoting the circulation of blood, stasis in gas, therefore specially control upper and lower all pains all over the body ".
Radix Rehmanniae meridian distribution of property and flavor, sweet, cold.GUIXIN, liver, kidney channel.(1) the existing anastalsis of the Radix Rehmanniae, has again blood coagulation resisting function.(2) antifungic action: Radix Rehmanniae water logging agent has inhibitory action to the growth of the multiple funguses such as trichophyton mentagrophytes, Gypsum Fibrosum sample microspore tinea bacterium, ulotrichy microspore's tinea bacterium and Du's big belly microspore tinea bacterium difficult to understand.(3) Radix Rehmanniae that affects of Endocrine has the inhibitory action of antagonism dexamethasone to Pituitary Adrenal cortex system, and can promote the synthetic of adrenocortical hormone.
Rhizoma Atractylodis acrid in the mouth, hardship, warm in nature; Return spleen, stomach warp; Virtue is strong dry loose, can rise and can fall, and walks and does not keep; Have drying damp and strengthening spleenly, ward off dirtyization turbid, expelling wind and cold, effect of improving eyesight; Cure mainly the spleen and stomach being stranded by dampness, gastral cavity painful abdominal mass abdominal distention, vomiting and nausea is had loose bowels, leukorrhagia stranguria with turbid discharge, pestilence, communicable subtropical diseases, malaria, cholera, rheumatism exogenous, cold-damp damp arthralgia, beriberi, flaccidity, nyctalopia.
Rhizoma Zingiberis is the dry product of Rhizoma Zingiberis Recens.Acrid in the mouth, hot in nature.Return spleen, stomach, the heart, lung meridian.Warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention.Cure mainly coldness and pain in the epigastrium, vomit, have loose bowels, YANG-depletion faint contrary, cold fluid-retention is breathed with cough, arthralgia due to cold-dampnes.
Rhizoma Chuanxiong is a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, the up top, mountain peak that reaches; Enter again blood system, the descending sea of blood that reaches.Blood circulation promoting and blood stasis dispelling effect is extensive, the various diseases of suitable stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.
Caulis Sargentodoxae, nature and flavor hardship, flat.There is the eliminating carbuncle of relieving internal heat, promoting blood circulation to remove obstruction in the collateral, the effect of wind dispelling insecticide.Control acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, injury from falling down.
Semen Cuscutae, abnormal smells from the patient is pungent, sweet, flat nontoxic.The kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones that is applicable to deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.
Caulis Lonicerae, sweet, cold.Attach to the lung and stomach meridians.Heat-clearing and toxic substances removing, dispelling wind dredging collateral.For epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, rheumatism pyretic arthralgia, redness and swelling of joints burning pain.
Rhizoma Corydalis, Papaveraceae, Corydalis perennial herb, another name: Rhizoma Corydalis, corydalis tuber, rhizoma corydalis, Rhizoma Corydalis.China's traditional medicine.Mainly originate in Zhejiang and Jiangsu.Its tuber (Rhizoma Corydalis Decumbentis), containing multiple alkaloids such as corydaline, protopines, through making powder or fluid-acet-extract etc., cures mainly all pains of trusted subordinate's waist knee joint; Menoxenia; Lump in the abdomen; Metrorrhagia; Puerperal blood faints; Lochiorrhea; Traumatic injury.There are analgesia, calmness, syngignoscism.
Herba Solani Lyrati, hardship, flat.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, anticancer.Herb: for cold, fever, icterohepatitis, cholecystitis, cholelithiasis, cancer, uterine erosion, leucorrhea, oedema due to nephritis; Carbuncle furuncle and phyma poison is controlled in external.Root: for rheumatic arthritis.
Herba Violae taste bitter, acrid, cold.GUIXIN, lung meridian.There is heat-clearing and toxic substances removing, removing heat from blood detumescence, the effect of clearing away heat-damp and promoting diuresis, cures mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.
Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times.The sweet cold fragrance of its property, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, and for various febrile diseases, as fever of the body, dermexanthesis, send out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, all effect is remarkable.
Herba Houttuyniae acrid in the mouth, cold, can heat-clearing and toxic substances removing, detumescence treats skin ulcer, promoting urination to remove dampness, clearing away heat to cure dysentery, invigorating the stomach and promoting digestion, be the lung abscess suffered from, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc. with controlling excess-heat, pyretic toxicity, damp, disease heat.Modern pharmacology experiment shows, the effects such as that this product has is antibacterial, antiviral, raising immunity of organisms, diuresis.
Cortex Moutan clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Rheumatism pyretic arthralgia.
Herba Fici Simplicissimae strengthening the spleen and tonifying the lung; Circulation of qi promoting dampness removing; Relaxing muscles and tendons and activating QI and blood in the collateral; Herba Fici Simplicissimae has the merit of strengthening the spleen and tonifying the lung, circulation of qi promoting dampness removing, relaxing muscles and tendons and activating QI and blood in the collateral, the disease such as the traditional Chinese medical science in area, the south of the Five Ridges or ethnic groups doctor among the people is usually used in treating that insufficiency of the spleen edema, lack of appetite are unable, pulmonary tuberculosis cough, night sweat, leukorrhagia, puerperal agalactia, menoxenia, rheumatic arthralgia, edema.
Radix Glycyrrhizae nature and flavor are sweet, flat, GUIXIN, lung, spleen, stomach warp, and function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Herba Lycopi's slightly warm in nature, bitter in the mouth, pungent.Blood circulation promoting and blood stasis dispelling, line water detumescence.For menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis stomachache, edema.
Herba Taraxaci, sweet, micro-hardship, cold.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
Radix Salviae Miltiorrhizae has promoting blood circulation to remove blood stasis, detumescence hemostasis, anti-inflammatory analgetic, menstruction regulating and pain relieving, coronary artery dilator, improve myocardial ischemia situation, reduce blood pressure, calm the nerves with all worries set aside, blood sugar lowering and the effect such as antibacterial, to menoxenia, amenorrhea dysmenorrhea, hematogenous blockage, traumatic injury, skin infection swell and ache, the disease such as vexed insomnia, angina pectoris has certain curative effect.Containing TANSHINONES, be robustness emmenagogue, there are blood stasis dispelling, tissue regeneration promoting, invigorate blood circulation, the effectiveness such as regulating menstruation, be gynecological's key medicine, cure mainly metrorrhagia, menoxenia, blood stasis, stomachache, dysmenorrhoea, amenorrhea, mausoleum pain.
Radix Picriae felterrae is bitter, cool.Enter the heart, liver, stomach, large intestine four warps.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, appetite-stimulating indigestion-relieving.For cold anemopyretic, laryngopharynx swelling and pain, dysentery, venom, traumatic injury, stomachache, dyspepsia.
Cortex Cinnamomi, complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, cold extremities faint pulse, YANG-depletion collapse, stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea lump in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.
Treat a preparation method for the Chinese medicine preparation of gynecological's endometritis, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 2cm ~ 3cm, soak 1.5-2h, take out medical material and put in extraction filling, decoct with water three times; Add for the first time the water of 8 times ~ 12 times of amounts of the gross weight of medical material, decoct 3h ~ 4h, collect decoction liquor for the first time, filter; Add for the second time the water that the 6-10 of the gross weight of medical material doubly measures, decoct 1.5h ~ 2h, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 0.5 hour ~ 1.5 hours, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to Chinese medicine preparation.
Wherein, described Chinese medicine preparation is tablet, capsule, granule, pill, powder, unguentum, oral liquid; According to prior art, Chinese medicine extract is made to above-mentioned Chinese medicine preparation.
compared with prior art, the present invention has following beneficial effect:
(1) Chinese medicine preparation for the treatment of gynecological's endometritis of the present invention, both Herba Commelinae, Herba Solani Lyrati, Herba Violae, Flos Lonicerae, Herba Houttuyniae, Radix Glycyrrhizae of heat-clearing and toxic substances removing, dampness removing leukorrhagia stopping, blood-activating analgetic etc. had been contained, contain again Radix Angelicae Sinensis, Rhizoma Corydalis, the Radix Rehmanniae, Herba Leonuri, Semen Cuscutae of warming the kidney to activate YANG, dispelling cold and removing dampness etc., composite by above-mentioned medicinal raw material, performance coordinative role, the Chinese medicine preparation making, heat-clearing and toxic substances removing, dampness removing blood stasis dispelling, warming the kidney to activate YANG, anti-inflammatory analgetic, take stopgap measures and effect a permanent cure, therapeutic effect is obvious, and healing time is short, and is difficult for recurrence more afterwards.Chinese medicine preparation for the treatment of gynecological's endometritis of the present invention, not only can effectively treat endometritis, and determined curative effect, also has good preventive effect to endometritis, have no side effect, and taking convenience.
(2) preparation method of the Chinese medicine preparation for the treatment of of the present invention gynecological endometritis is simple, and raw material is easy to get, and is applicable to industry and promotes, and has good economic benefit and social benefit widely.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in detail.
embodiment 1
A kind of Chinese medicine preparation for the treatment of gynecological's endometritis, by weight, it comprises the medicinal raw material of following weight portion: 25 parts of Herba Commelinaes, 8 parts of the Radixs Astragali, 3 parts of Rhizoma Cyperi, 5 parts of Herba Cistanches, 3 parts of Fructus Rubies, 30 parts of Radix Angelicae Sinensis, 25 parts, Poria, 30 parts of the Radix Paeoniae Albas, 20 parts of Herba Leonuris, 25 parts of Herba Dendrobiis, 5 parts of Radix seu Herba Spiranthis Lanceae, 8 parts of Rhizoma Corydalis, 1 part, the Radix Rehmanniae, 5 parts of Rhizoma Atractylodis, 8 parts of Rhizoma Zingiberiss, 5 parts of Rhizoma Chuanxiongs, 1 part of Caulis Sargentodoxae, 5 parts of Semen Cuscutae, 1 part of Caulis Lonicerae, 3 parts of Rhizoma Corydalis, 3 parts of Herba Solani Lyratis, 5 parts of Herba Violaes, 3 parts of Flos Loniceraes, 8 parts of Herba Houttuyniae, 8 parts of Cortex Moutans, 12 parts of Herba Fici Simplicissimae, 8 parts of Radix Glycyrrhizae.
Treat a preparation method for the Chinese medicine preparation of gynecological's endometritis, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 2cm, soak 1.5, take out medical material and put in extraction filling, decoct with water three times; 8 times of water of doubly measuring that add for the first time the gross weight of medical material, decoct 4h, collect decoction liquor for the first time, filter; Add for the second time the water of 6 times of amounts of the gross weight of medical material, decoct 1.5h ~ 2h, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 1.5 hours, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to Chinese medicinal tablet preparation.
embodiment 2
A kind of Chinese medicine preparation for the treatment of gynecological's endometritis, by weight, it comprises the medicinal raw material of following weight portion: 25 parts of Herba Commelinaes, 8 parts of the Radixs Astragali, 3 parts of Rhizoma Cyperi, 5 parts of Herba Cistanches, 3 parts of Fructus Rubies, 27 parts of Radix Angelicae Sinensis, 28 parts, Poria, 25 parts of the Radix Paeoniae Albas, 25 parts of Herba Leonuris, 20 parts of Herba Dendrobiis, 5 parts of Radix seu Herba Spiranthis Lanceae, 7 parts of Rhizoma Corydalis, 1 part, the Radix Rehmanniae, 1 part of Rhizoma Atractylodis, 8 parts of Rhizoma Zingiberiss, 1 part of Rhizoma Chuanxiong, 3 parts of Caulis Sargentodoxae, 1 part of Semen Cuscutae, 2 parts of Caulis Loniceraes, 1 part of Rhizoma Corydalis, 3 parts of Herba Solani Lyratis, 4 parts of Herba Violaes, 4 parts of Flos Loniceraes, 6 parts of Herba Houttuyniae, 11 parts of Cortex Moutans, 8 parts of Herba Fici Simplicissimae, 8 parts of Radix Glycyrrhizae.
Treat a preparation method for the Chinese medicine preparation of gynecological's endometritis, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 2.5cm ~ 3cm, soak 1.6h, take out medical material and put in extraction filling, decoct with water three times; Add for the first time the water of 9 times of amounts of the gross weight of medical material, decoct 3.8h, collect decoction liquor for the first time, filter; Add for the second time the water of 7 times of amounts of the gross weight of medical material, decoct 1.8h, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 1.3 hours, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to Chinese medicinal capsule agent formulation.
embodiment 3
A kind of Chinese medicine preparation for the treatment of gynecological's endometritis, by weight, it comprises the medicinal raw material of following weight portion: 27 parts of Herba Commelinaes, 7 parts of the Radixs Astragali, 4 parts of Rhizoma Cyperi, 4 parts of Herba Cistanches, 4 parts of Fructus Rubies, 25 parts of Radix Angelicae Sinensis, 30 parts, Poria, white 26 parts, 30 parts of Herba Leonuri, 22 parts of Herba Dendrobiis, 6 parts of Radix seu Herba Spiranthis Lanceae, 8 parts of Rhizoma Corydalis, 3 parts, the Radix Rehmanniae, 3 parts of Rhizoma Atractylodis, 10 parts of Rhizoma Zingiberiss, 3 parts of Rhizoma Chuanxiongs, 5 parts of Caulis Sargentodoxae, 3 parts of Semen Cuscutae, 1 part of Caulis Lonicerae, 2 parts of Rhizoma Corydalis, 4 parts of Herba Solani Lyratis, 5 parts of Herba Violaes, 5 parts of Flos Loniceraes, 8 parts of Herba Houttuyniae, 12 parts of Cortex Moutans, 10 parts of Herba Fici Simplicissimae, 9 parts of Radix Glycyrrhizae.
Treat a preparation method for the Chinese medicine preparation of gynecological's endometritis, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 2.6cm, soak 1.7h, take out medical material and put in extraction filling, decoct with water three times; Add for the first time the water of 10 times of amounts of the gross weight of medical material, decoct 3.6h, collect decoction liquor for the first time, filter; Add for the second time the water of 8 times of amounts of the gross weight of medical material, decoct 1.7h, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 1.2 hours, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to Chinese medicinal granule agent formulation.
embodiment 4
A kind of Chinese medicine preparation for the treatment of gynecological's endometritis, by weight, it comprises the medicinal raw material of following weight portion: 28 parts of Herba Commelinaes, 6 parts of the Radixs Astragali, 4 parts of Rhizoma Cyperi, 4 parts of Herba Cistanches, 4 parts of Fructus Rubies, 30 parts of Radix Angelicae Sinensis, 25 parts, Poria, 30 parts of the Radix Paeoniae Albas, 20 parts of Herba Leonuris, 25 parts of Herba Dendrobiis, 7 parts of Radix seu Herba Spiranthis Lanceae, 6 parts of Rhizoma Corydalis, 4 parts, the Radix Rehmanniae, 5 parts of Rhizoma Atractylodis, 10 parts of Rhizoma Zingiberiss, 5 parts of Rhizoma Chuanxiongs, 1 part of Caulis Sargentodoxae, 5 parts of Semen Cuscutae, 2 parts of Caulis Loniceraes, 3 parts of Rhizoma Corydalis, 4 parts of Herba Solani Lyratis, 4 parts of Herba Violaes, 3 parts of Flos Loniceraes, 5 parts of Herba Houttuyniae, 8 parts of Cortex Moutans, 12 parts of Herba Fici Simplicissimae, 10 parts of Radix Glycyrrhizae.
Treat a preparation method for the Chinese medicine preparation of gynecological's endometritis, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 2cm ~ 3cm, soak 1.5-2h, take out medical material and put in extraction filling, decoct with water three times; Add for the first time the water of 8 times ~ 12 times of amounts of the gross weight of medical material, decoct 3h ~ 4h, collect decoction liquor for the first time, filter; Add for the second time the water that the 6-10 of the gross weight of medical material doubly measures, decoct 1.5h ~ 2h, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 0.5 hour ~ 1.5 hours, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to Chinese medicine preparation.
Wherein, described Chinese medicine preparation is tablet, capsule, granule, pill, powder, unguentum, oral liquid; According to prior art, Chinese medicine extract is made to above-mentioned Chinese medicine preparation.
embodiment 5
A kind of Chinese medicine preparation for the treatment of gynecological's endometritis, by weight, it comprises the medicinal raw material of following weight portion: 29 parts of Herba Commelinaes, 5 parts of the Radixs Astragali, 5 parts of Rhizoma Cyperi, 3 parts of Herba Cistanches, 5 parts of Fructus Rubies, 29 parts of Radix Angelicae Sinensis, 26 parts, Poria, 28 parts of the Radix Paeoniae Albas, 23 parts of Herba Leonuris, 24 parts of Herba Dendrobiis, 7 parts of Radix seu Herba Spiranthis Lanceae, 6 parts of Rhizoma Corydalis, 5 parts, the Radix Rehmanniae, 4 parts of Rhizoma Atractylodis, 12 parts of Rhizoma Zingiberiss, 4 parts of Rhizoma Chuanxiongs, 2 parts of Caulis Sargentodoxae, 4 parts of Semen Cuscutae, 3 parts of Caulis Loniceraes, 2 parts of Rhizoma Corydalis, white 4-5 part, 3 parts of Herba Violaes, 4 parts of Flos Loniceraes, 3 parts of Herba Houttuyniae, 9 parts of Cortex Moutans, 11 parts of Herba Fici Simplicissimae, 11 parts of Radix Glycyrrhizae, 1 part of Herba Lycopi, 5 parts of Herba Taraxacis.
Treat a preparation method for the Chinese medicine preparation of gynecological's endometritis, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 2.8cm, soak 1. 6h, take out medical material and put in extraction filling, decoct with water three times; Add for the first time the water of 10 times of amounts of the gross weight of medical material, decoct 3.5h, collect decoction liquor for the first time, filter; Add for the second time the water of 9 times of amounts of the gross weight of medical material, decoct 1.6, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 1 hour, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to medicine pill preparation.
embodiment 6
A kind of Chinese medicine preparation for the treatment of gynecological's endometritis, by weight, it comprises the medicinal raw material of following weight portion: 27 parts of Herba Commelinaes, 7 parts of the Radixs Astragali, 4 parts of Rhizoma Cyperi, 4 parts of Herba Cistanches, 3 parts of Fructus Rubies, 29 parts of Radix Angelicae Sinensis, 27 parts, Poria, 28 parts of the Radix Paeoniae Albas, 23 parts of Herba Leonuris, 24 parts of Herba Dendrobiis, 6 parts of Radix seu Herba Spiranthis Lanceae, 7 parts of Rhizoma Corydalis, 3 parts, the Radix Rehmanniae, 3 parts of Rhizoma Atractylodis, 9 parts of Rhizoma Zingiberiss, 4 parts of Rhizoma Chuanxiongs, 2 parts of Caulis Sargentodoxae, 4 parts of Semen Cuscutae, 2 parts of Caulis Loniceraes, 3 parts of Rhizoma Corydalis, 3 parts of Herba Solani Lyratis, 4 parts of Herba Violaes, 4 parts of Flos Loniceraes, 7 parts of Herba Houttuyniae, 9 parts of Cortex Moutans, 10 parts of Herba Fici Simplicissimae, 9 parts of Radix Glycyrrhizae, 5 parts of Radix Salviae Miltiorrhizaes.
Treat a preparation method for the Chinese medicine preparation of gynecological's endometritis, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 2.8cm, soak 1.8, take out medical material and put in extraction filling, decoct with water three times; Add for the first time the water of 11 times of amounts of the gross weight of medical material, decoct 4h, collect decoction liquor for the first time, filter; Add for the second time the water of 9 times of amounts of the gross weight of medical material, decoct 2h, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 1.5 hours, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to Chinese powder medicine preparation.
embodiment 7
A kind of Chinese medicine preparation for the treatment of gynecological's endometritis, by weight, it comprises the medicinal raw material of following weight portion: 29 parts of Herba Commelinaes, 6 parts of the Radixs Astragali, 5 parts of Rhizoma Cyperi, 3 parts of Herba Cistanches, 4 parts of Fructus Rubies, 27 parts of Radix Angelicae Sinensis, 29 parts, Poria, 26 parts of the Radix Paeoniae Albas, 26 parts of Herba Leonuris, 22 parts of Herba Dendrobiis, 7 parts of Radix seu Herba Spiranthis Lanceae, 6 parts of Rhizoma Corydalis, 4 parts, the Radix Rehmanniae, 2 parts of Rhizoma Atractylodis, 10 parts of Rhizoma Zingiberiss, 3 parts of Rhizoma Chuanxiongs, 4 parts of Caulis Sargentodoxae, 3 parts of Semen Cuscutae, 3 parts of Caulis Loniceraes, 2 parts of Rhizoma Corydalis, 4 parts of Herba Solani Lyratis, 3 parts of Herba Violaes, 5 parts of Flos Loniceraes, 5 parts of Herba Houttuyniae, 10 parts of Cortex Moutans, 9 parts of Herba Fici Simplicissimae, 10 parts of Radix Glycyrrhizae, 3 parts of Radix Picriae felterrae.
Treat a preparation method for the Chinese medicine preparation of gynecological's endometritis, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 3cm, soak 1.5h, take out medical material and put in extraction filling, decoct with water three times; 8 times of water of doubly measuring that add for the first time the gross weight of medical material, decoct 4h, collect decoction liquor for the first time, filter; Add for the second time the water of 10 times of amounts of the gross weight of medical material, decoct 2h, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 0.5 hour, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to Chinese medicinal ointment preparation.
embodiment 8
A kind of Chinese medicine preparation for the treatment of gynecological's endometritis, by weight, it comprises the medicinal raw material of following weight portion: 28 parts of Herba Commelinaes, 6.5 parts of the Radixs Astragali, 4.5 parts of Rhizoma Cyperi, 3.5 parts of Herba Cistanches, 3.5 parts of Fructus Rubies, 28 parts of Radix Angelicae Sinensis, 28 parts, Poria, 27 parts of the Radix Paeoniae Albas, 25 parts of Herba Leonuris, 23 parts of Herba Dendrobiis, 6.5 parts of Radix seu Herba Spiranthis Lanceae, 6.5 parts of Rhizoma Corydalis, 3.5 parts, the Radix Rehmanniae, 2.5 parts of Rhizoma Atractylodis, 9.5 parts of Rhizoma Zingiberiss, 3.5 parts of Rhizoma Chuanxiongs, 3 parts of Caulis Sargentodoxae, Semen Cuscutae 3.5-4 part, 2.5 parts of Caulis Loniceraes, 2.5 parts of Rhizoma Corydalis, 3.5 parts of Herba Solani Lyratis, 3.5 parts of Herba Violaes, 4.5 parts of Flos Loniceraes, 6 parts of Herba Houttuyniae, 9.5 parts of Cortex Moutans, 9.5 parts of Herba Fici Simplicissimae, 9.5 parts of Radix Glycyrrhizae, 3 parts of Herba Lycopi, 3 parts of Herba Taraxacis, 5 parts of Radix Salviae Miltiorrhizaes, 3 parts of Radix Picriae felterrae, 13 parts of Cortex Cinnamomis.
Treat a preparation method for the Chinese medicine preparation of gynecological's endometritis, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 3cm, soak 1.5h, take out medical material and put in extraction filling, decoct with water three times; Add for the first time the water of 10 times of amounts of the gross weight of medical material, decoct 3h, collect decoction liquor for the first time, filter; Add for the second time the water of 9 times of amounts of the gross weight of medical material, decoct 2h, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 1 hour, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to extract oral liquid preparation.
the relevant toxicity test of the present invention, pharmacodynamics situation:
One, a kind of Chinese medicine preparation for the treatment of gynecological's endometritis of the present invention and preparation method thereof long term toxicity test
1, by Chinese medicine three class examination & approval requirements, with Chinese medicine preparation of the present invention, rat is carried out the long term toxicity test of continuous 28 days, and mice is carried out to acute toxicity test, result shows, the aspects such as general status, organ coefficient, routine blood test, blood parameters and the histopathology of Chinese medicine preparation of the present invention to animal have no obvious toxic reaction.
2, test objective: observe Chinese medicine preparation of the present invention rat is carried out to toxic reaction and the degree thereof that long-term gastric infusion produces, to determine the safety of clinical application.
3, test method
3.1 long term toxicity test
Rat and pig are carried out to long term toxicity test, choosing assorted is 25 of rat, body weight 85.3 ± 15.1g, male and female dual-purpose, points three groups, heavy dose of group gavages 0.72g/kg (for 15 times of clinical daily dose) every day, and small dose group gavages 0.36g/kg (for 7.5 times of clinical daily dose) every day, matched group gavages equal-volume normal saline, continuous 28 days every day.For the body weight gain of examination animal, hepatic and renal function, hemogram are showed no extremely, and main organs histological examination is similar to matched group, has no special.
3.2 medications: gavage medicine every day 1 time, continuous 28 days.
4, observing time: continuous 28 days.
5, observation index
After last administration, take a blood sample and make liver, renal function and hemogram checking next day to rat, cuts open and get thymus, spleen is weighed, and get internal organs major organs and do histological examination, with matched group comparison.
6, result
6.1 administration group growth curves are close with matched group, area under a curve and matched group there was no significant difference (P > 0.05).
Liver, renal function and the hemogram checking result of 6.2 administration groups are close with matched group, there are no extremely; Thymus, spleen weight and the matched group of administration group are close, there was no significant difference (P > 0.05).
6.3 hearts, lung, liver,kidney,spleen, adrenal gland, gastric tissue check similar to matched group, have no special.
7, evaluation of result
Long term toxicity test results suggest, Chinese medicine preparation of the present invention is without obvious toxic and side effects, therefore think by clinical plan dosage and to use Chinese medicine preparation of the present invention the course for the treatment of be safer.
Two, a kind of Chinese medicine preparation for the treatment of gynecological's endometritis of the present invention and preparation method thereof pharmacodynamics test
The Chinese medicine preparation of the treatment gynecological endometritis of Application Example 1 ~ 8 preparation, spy carries out clinical observation.
1, case selection: choose 2010 so far, use altogether the present invention to treat endometritis 956 examples.
2, Therapeutic Method: every day potion, point sooner or later take, within 20 days, be a course for the treatment of, can heal a general course for the treatment of, unhealed continues to take medicine, until fully recover.Take 2 the course for the treatment of state of an illness without improvement person, fail to respond to any medical treatment, discontinue medication.
3, curative effect judging standard and therapeutic outcome
3.1 curative effect judgements: endometritis: effective, clinical symptoms all disappears; Effectively, clinical symptoms improvement is invalid; Invalid, clinical symptoms is unchanged or increase the weight of.
3.2 efficacy result
| Case load | Effective effective | Effectively | Invalid | Total effective rate |
| 956 | 912 | 28 | 16 | 98.3% |
As can be seen here, the Chinese medicine preparation for the treatment of of the present invention gynecological endometritis has no side effect, and effective percentage reaches 98.3%, and healing person follows up a case by regular visits to 1 year, not recurrence; Take stopgap measures and effect a permanent cure, therapeutic effect is obvious, and healing time is short.
Finally should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention; but not limiting the scope of the invention; although the present invention has been done to explain with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; can modify or be equal to replacement technical scheme of the present invention, and not depart from essence and the scope of technical solution of the present invention.
Claims (10)
1. treat the Chinese medicine preparation of gynecological's endometritis for one kind, it is characterized in that: by weight, it comprises the medicinal raw material of following weight portion: Herba Commelinae 25-30 part, Radix Astragali 5-8 part, Rhizoma Cyperi 3-5 part, Herba Cistanches 3-5 part, Fructus Rubi 3-5 part, Radix Angelicae Sinensis 25-30 part, Poria 25-30 part, Radix Paeoniae Alba 25-30 part, Herba Leonuri 20-30 part, Herba Dendrobii 20-25 part, Radix seu Herba Spiranthis Lanceae 5-8 part, Rhizoma Corydalis 5-8 part, Radix Rehmanniae 1-5 part, Rhizoma Atractylodis 1-5 part, Rhizoma Zingiberis 8-12 part, Rhizoma Chuanxiong 1-5 part, Caulis Sargentodoxae 1-5 part, Semen Cuscutae 1-5 part, Caulis Lonicerae 1-3 part, Rhizoma Corydalis 1-3 part, Herba Solani Lyrati 3-5 part, Herba Violae 3-5 part, Flos Lonicerae 3-5 part, Herba Houttuyniae 3-8 part, Cortex Moutan 8-12 part, Herba Fici Simplicissimae 8-12 part, Radix Glycyrrhizae 8-12 part.
2. Chinese medicine preparation for the treatment of gynecological's endometritis according to claim 1, it is characterized in that: by weight, it comprises the medicinal raw material of following weight portion: Herba Commelinae 25-27 part, Radix Astragali 7-8 part, Rhizoma Cyperi 3-4 part, Herba Cistanches 4-5 part, Fructus Rubi 3-4 part, Radix Angelicae Sinensis 25-27 part, Poria 28-30 part, Radix Paeoniae Alba 25-26 part, Herba Leonuri 25-30 part, Herba Dendrobii 20-22 part, Radix seu Herba Spiranthis Lanceae 5-6 part, Rhizoma Corydalis 7-8 part, Radix Rehmanniae 1-3 part, Rhizoma Atractylodis 1-3 part, Rhizoma Zingiberis 8-10 part, Rhizoma Chuanxiong 1-3 part, Caulis Sargentodoxae 3-5 part, Semen Cuscutae 1-3 part, Caulis Lonicerae 1-2 part, Rhizoma Corydalis 1-2 part, Herba Solani Lyrati 3-4 part, Herba Violae 4-5 part, Flos Lonicerae 4-5 part, Herba Houttuyniae 6-8 part, Cortex Moutan 11-12 part, Herba Fici Simplicissimae 8-10 part, Radix Glycyrrhizae 8-9 part.
3. Chinese medicine preparation for the treatment of gynecological's endometritis according to claim 1, it is characterized in that: by weight, it comprises the medicinal raw material of following weight portion: Herba Commelinae 28-30 part, Radix Astragali 5-6 part, Rhizoma Cyperi 4-5 part, Herba Cistanches 3-4 part, Fructus Rubi 4-5 part, Radix Angelicae Sinensis 28-30 part, Poria 25-27 part, Radix Paeoniae Alba 27-30 part, Herba Leonuri 20-25 part, Herba Dendrobii 23-25 part, Radix seu Herba Spiranthis Lanceae 7-8 part, Rhizoma Corydalis 5-6 part, Radix Rehmanniae 4-5 part, Rhizoma Atractylodis 4-5 part, Rhizoma Zingiberis 10-12 part, Rhizoma Chuanxiong 4-5 part, Caulis Sargentodoxae 1-2 part, Semen Cuscutae 4-5 part, Caulis Lonicerae 2-3 part, Rhizoma Corydalis 2-3 part, Herba Solani Lyrati 4-5 part, Herba Violae 3-4 part, Flos Lonicerae 3-4 part, Herba Houttuyniae 3-5 part, Cortex Moutan 8-10 part, Herba Fici Simplicissimae 11-12 part, Radix Glycyrrhizae 10-12 part.
4. Chinese medicine preparation for the treatment of gynecological's endometritis according to claim 1, it is characterized in that: by weight, it comprises the medicinal raw material of following weight portion: Herba Commelinae 27-29 part, Radix Astragali 6-7 part, Rhizoma Cyperi 4-5 part, Herba Cistanches 3-4 part, Fructus Rubi 3-4 part, Radix Angelicae Sinensis 27-29 part, Poria 27-29 part, Radix Paeoniae Alba 26-28 part, Herba Leonuri 23-26 part, Herba Dendrobii 22-24 part, Radix seu Herba Spiranthis Lanceae 6-7 part, Rhizoma Corydalis 6-7 part, Radix Rehmanniae 3-4 part, Rhizoma Atractylodis 2-3 part, Rhizoma Zingiberis 9-10 part, Rhizoma Chuanxiong 3-4 part, Caulis Sargentodoxae 2-4 part, Semen Cuscutae 3-4 part, Caulis Lonicerae 2-3 part, Rhizoma Corydalis 2-3 part, Herba Solani Lyrati 3-4 part, Herba Violae 3-4 part, Flos Lonicerae 4-5 part, Herba Houttuyniae 5-7 part, Cortex Moutan 9-10 part, Herba Fici Simplicissimae 9-10 part, Radix Glycyrrhizae 9-10 part.
5. Chinese medicine preparation for the treatment of gynecological's endometritis according to claim 1, is characterized in that: by weight, also comprise the Herba Lycopi of 1-5 weight portion and the Herba Taraxaci of 1-5 weight portion.
6. Chinese medicine preparation for the treatment of gynecological's endometritis according to claim 1, is characterized in that: by weight, also comprise the Radix Salviae Miltiorrhizae of 3-8 weight portion.
7. the Chinese medicine preparation for the treatment of according to claim 1 gynecological endometritis, is characterized in that: by weight, it also comprises the Radix Picriae felterrae of 1-5 weight portion.
8. the Chinese medicine preparation for the treatment of according to claim 1 gynecological endometritis, is characterized in that: by weight, it also comprises the Cortex Cinnamomi of 10-15 weight portion.
9. a preparation method for the Chinese medicine preparation of the treatment gynecological endometritis described in claim 1 to 8 any one, is characterized in that, described preparation process is as follows:
(1) get the medicinal raw material of recipe quantity, clean roguing, dry, be ground into graininess medical material;
(2) more above-mentioned graininess medical material is added water and covers powder 2cm ~ 3cm, soak 1.5-2h, take out medical material and put in extraction filling, decoct with water three times; Add for the first time the water of 8 times ~ 12 times of amounts of the gross weight of medical material, decoct 3h ~ 4h, collect decoction liquor for the first time, filter; Add for the second time the water that the 6-10 of the gross weight of medical material doubly measures, decoct 1.5h ~ 2h, collect decoction liquor for the second time, filter; The water of 4 times of amounts of the gross weight that amount of water is medical material for the third time, decocts 0.5 hour ~ 1.5 hours, collects decoction liquor for the third time; Decoct by three times the decoction liquor making and merge, filter;
(3) at 55 DEG C, be evaporated to relative density 1.05, filter, obtain filtrate, the concentrated solution that while being concentrated into 90 DEG C, relative density is 1.10, makes Chinese medicine extract, for subsequent use;
(4) Chinese medicine extract is made to Chinese medicine preparation.
10. the preparation method of Chinese medicine preparation for the treatment of gynecological's endometritis according to claim 9, is characterized in that: described Chinese medicine preparation is tablet, capsule, granule, pill, powder, unguentum, oral liquid.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104826063A (en) * | 2015-05-15 | 2015-08-12 | 济南科纳信息科技有限公司 | Traditional Chinese medicine lotion for treating endometritis |
| CN105456531A (en) * | 2015-12-16 | 2016-04-06 | 韩秀敏 | Drug composition for treating yin deficiency and internal heat type pyometra and preparation method thereof |
| CN105999155A (en) * | 2016-06-15 | 2016-10-12 | 山东中医药大学附属医院 | Traditional Chinese medicine for treating thin endometrium |
| CN106075093A (en) * | 2016-08-24 | 2016-11-09 | 路明芳 | A kind of Chinese medicine treating pelvic inflammatory disease |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104826063A (en) * | 2015-05-15 | 2015-08-12 | 济南科纳信息科技有限公司 | Traditional Chinese medicine lotion for treating endometritis |
| CN105456531A (en) * | 2015-12-16 | 2016-04-06 | 韩秀敏 | Drug composition for treating yin deficiency and internal heat type pyometra and preparation method thereof |
| CN105999155A (en) * | 2016-06-15 | 2016-10-12 | 山东中医药大学附属医院 | Traditional Chinese medicine for treating thin endometrium |
| CN105999155B (en) * | 2016-06-15 | 2019-11-15 | 山东中医药大学附属医院 | It is a kind of to treat the thin Chinese medicine of endometrium |
| CN106075093A (en) * | 2016-08-24 | 2016-11-09 | 路明芳 | A kind of Chinese medicine treating pelvic inflammatory disease |
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