CN100515443C - Medicine for treating gynecological inflammation disease and its preparation process - Google Patents
Medicine for treating gynecological inflammation disease and its preparation process Download PDFInfo
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Abstract
The invention relates to a medicament for treating gynaecologic inflammations and process for preparation, wherein the raw materials include (by weight portions) cnidium fruit 40-80 parts, flavescent sophora root 40-75 parts, rheum officinale 10-30 parts, astragalus root 0-60 parts, Chinese angelica root 10-50 parts, Chinese mugwort leaf 30-60 parts, panicled swallowwort root 20-60 parts, yellow corktree bark 30-60 parts, borneol 1-8 parts and azone 2-5 parts.
Description
Technical field
The present invention relates to medicine field, particularly a kind ofly be used for the treatment of gynaecological inflammation disease medicine (being called for short woman's cleaning) and preparation method thereof with what natural plants Chinese medicine was raw material and four kinds of chemical polymer substances as adjuvant.
Background technology
Gynecological inflammation is a kind of commonly encountered diseases, and frequently-occurring disease is perplexing female patient for a long time, serious harm they healthy, even give on their soul and also bring huge shade and wound.The patient usually feels the pain of itching in the affected part, abnormal flavour is arranged, and uneasy in either sitting or lying also causes infectious fever sometimes, influences operate as normal study.A lot of DeGrains in the existing medicine, some of them also contain the hormone composition, though can the respite symptom, " curing the symptoms, not the disease ", outbreak repeatedly easily.Owing to contain the hormone composition, side effect is big, so unsuitable long-term large tracts of land is used.And general chemical drugs costs an arm and a leg, and brings heavy economic pressures to the patient.
Summary of the invention
Technical problem to be solved by this invention is: based on understanding and the Therapeutic Principle of China's traditional Chinese medical science medical science to the treatment gynaecological inflammation disease, provide a kind of and can effectively treat gynecological inflammation, toxic and side effects is little again, and is different from not significantly woman's cleaning of drawback and preparation method thereof of Chinese medicine dosage form curative effect in the past.
The present invention solves its technical problem and adopts following technical scheme:
A kind of treatment gynaecological inflammation disease medicine provided by the invention, by weight, its combination formula comprises following raw material: 40～80 parts of Fructus Cnidiis, 40～75 parts of Radix Sophorae Flavescentiss, 10～30 parts of Radix Et Rhizoma Rhei, 0～60 part of the Radix Astragali, 10～50 parts of Radix Angelicae Sinensis, 30～60 parts of Folium Artemisiae Argyis, 20～60 parts of Radix Cynanchi Paniculatis, 30～60 parts of Cortex Phellodendris, 1～8 part of Borneolum Syntheticum, 2～5 parts of azones.
Above-mentioned medicine, by weight, its combination formula can also comprise four kinds of chemical polymer substances as adjuvant, that is: surfactant benzene benzyl bromine ammonium is 0.2～0.8 part, film former PVP3～8 part, 2～8 parts of quaternized vinylpyrrolidones, 1～5 part in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium.
The method of the above-mentioned treatment gynaecological inflammation disease of preparation provided by the invention medicine, its step comprises: raw material is pressed formula proportion mix, add 10～20 times of decoctings and boiled 3～4 hours; After the filtration, medicinal residues are added 8～10 times of water decocted again 1～2 hour; Merging filtrate, concentrated filtrate; Press formula proportion again and add adjuvant; Through stirring, filtration, canned and add gas disposal, promptly get described treatment gynaecological inflammation disease medicine then.
The present invention compares with Chinese medicine, and its beneficial effect is:
One. employed primary raw material is a natural plants Chinese medicine, meets traditional Chinese medical science combination formula theory, and the chemical macromolecule adjuvant of interpolation makes it be different from traditional form of Chinese drug, better efficacy.
They are two years old. except effectively treating the various common gynecologic inflammation, the vaginitis that pathogenic bacteria, virus, cleaning vaginal secretions and the infection of interior pudendum that unclean sexual intercourse is propagated causes, urethritis, cervical erosion, pruritus vulvae, leucorrhea abnormal, eczema, vagina abnormal flavour, sexually transmitted disease (STD) etc. all have effects such as stronger sterilization, antiinflammatory and sterilization.
They are three years old. have the YAOJING of choosing, and good effect, attention whole structure and partial result are taken into account, instant effect, the cure rate height has no side effect, and takes safety, and processing technology is simple, and cost is low.
Its four, when using this medicine, can produce fine foam in affected part moment, foam leave the back rapidly formation can slowly discharge the medical releasing film of drug effect, and be close to the affected part, to reach better therapeutic.
In a word, woman's cleaning provided by the invention can reach the purpose of effective treatment gynaecological inflammation disease, have cheapness, easy to use, evident in efficacy, antipruritic, pain relieving, antiviral, antiallergic and have no side effect, and preparation technology is simple.
The specific embodiment
The invention provides the clean medicine of a kind of woman evident in efficacy and easy to use, and the preparation method of this medicine.
The invention will be further described below in conjunction with embodiment, but do not limit the present invention.
One. be used for the clean medicine of woman of gynaecological inflammation disease
Example 1. by weight, the combination formula of the clean medicine of woman is:
40～80 parts of Fructus Cnidiis, 40～75 parts of Radix Sophorae Flavescentiss, 10～30 parts of Radix Et Rhizoma Rhei, 0～60 part of the Radix Astragali, 10～50 parts of Radix Angelicae Sinensis, 30～60 parts of Folium Artemisiae Argyis, 20～60 parts of Radix Cynanchi Paniculatis, 30～60 parts of Cortex Phellodendris, 1～8 part of Borneolum Syntheticum, 2～5 parts of azones.
Example 2. is on the basis of example 1, and the combination formula of the clean medicine of woman also has adjuvant:
Four kinds of chemical polymer substances: 0.2～0.8 part of surfactant benzene benzyl bromine ammonium, film former PVP3～8 part, 2～8 parts of quaternized vinylpyrrolidones, 1～5 part in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium.
Example 3. by weight, the combination formula of the clean medicine of woman is made up of following raw material: 60 parts of Fructus Cnidiis, 55 parts of Radix Sophorae Flavescentiss, 20 parts of Radix Et Rhizoma Rhei, 50 parts of the Radixs Astragali, 30 parts of Radix Angelicae Sinensis, 45 parts of Folium Artemisiae Argyis, 40 parts of Radix Cynanchi Paniculatis, 40 parts of Cortex Phellodendris, 6 parts of Borneolum Syntheticums, 4 parts of azones; 0.5 part of surfactant benzene benzyl bromine ammonium, film former PVP5 part, 6 parts of quaternized vinylpyrrolidones, 3 parts in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium.
Above-mentioned raw materials and adjuvant are all commercially available.The effect and the synergism of its primary raw material and main additives are summarized as follows:
Fructus Cnidii: natural plants Chinese medicine is the mature fruit of samphire Fructus Cnidii; Hot, bitter, temperature is gone into kidney channel; Warming the kidney to invigorate YANG is arranged, the effect of removing dampness and killing parasites; Be used for the treatment of impotence due to deficiency of the kidney clinically, the woman is sterile, pudendum pruritus due to damp pathogen, scabies, diseases such as stubborn dermatitis.
Radix Sophorae Flavescentis: natural plants Chinese medicine is the root of leguminous plant Radix Sophorae Flavescentis; Hardship, cold.Go into the heart, liver, small intestinal, large intestine, stomach warp; Heat clearing and damp drying is arranged, the effect of wind dispelling insecticide; Be used for the treatment of damp-heat diarrhea clinically, jaundice, leucorrhea with red and white discharge, pudendal pruritus, whole body pruritus due to wind pathogen, scabies stubborn dermatitis, diseases such as leprosy.
Radix Et Rhizoma Rhei: natural plants Chinese medicine, return big bitter Great Cold through: go into foot lunar (spleen), brothers' yangming syncope the moon (big the intestines and stomach pericardium liver) blood system; Following effect is arranged: (1) its property is floating, and it is not kept with walking and not heavy, if steeping in wine also can cause paramount branch.(2) in order to cleansing the intestines and stomach, following dryness accumulated in the stomach and intestine and remove stagnant heat.(3) go the water expectorant, the detumescence of erosion pus can push away Chen Zhixin; Disease when being used for the treatment of typhoid fever clinically, fever and delirium, warm subtertian malaria, dysentery is red white, the stomachache pain in the abdomen, the jaundice edema, lump in the abdomen prolonged fluid-retention dyspepsia, trusted subordinate's feeling of fullness, constipation and anuresis, hematemesis and epistaxis, blood closes blood depletion, damage hematocele, all excess-heat, diseases such as the blood fire second of the three ten-day periods of the hot season.
The Radix Astragali: natural plants Chinese medicine is the dry root of leguminous plant Radix Astagali or Radix Astragali; Slightly warm in nature, sweet in the mouth; The effect that invigorating QI to consolidate the body surface resistance, hidroschesis detoxification, granulation promoting, diuresis, detumescent are arranged; It is weak to be used for the treatment of the deficiency of vital energy clinically, sinking of QI of middle-JIAO, and the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diseases such as diabetes.
Radix Angelicae Sinensis: natural plants Chinese medicine is the root of umbelliferae angelica; Sweet, hot, temperature.Go into liver, the heart, spleen channel; Tonifying blood and regulating menstruation is arranged, the effect of promoting blood circulation and stopping pain; Be used for menoxenia clinically, dysmenorrhea, amenorrhea, metrorrhagia, blood deficiency is weak, traumatic injury, stasis of blood pain, carbuncle stasis pain, puerperal the stasis of blood stomachache that stagnates, disease such as rheumatic arthralgia and meridians are unfavorable.
Folium Artemisiae Argyi: natural plants Chinese medicine is the leaf of Compositae herbaceos perennial Chinese mugwort; Toil is given birth to temperature, ripe heat, the property of pure sun; The exhausted Yuanyang of hanging down is arranged back, and logical 12 warps are walked three the moon, the blood of regulating the flow of vital energy, and by cold-damp, all blood is ended, warming middle-JIAO dissipating depression of QI, the effect that regulating menstruation is antiabortive in warm uterus; Be mainly used in treatment clinically and tell the nosebleed metrorrhagia and leukorrhagia, the stomachache cold-dysentery, cramp caused by acute vomiting and diarrhea kills Serpentis and controls tinea.
Radix Cynanchi Paniculati: natural plants Chinese medicine is the root and rhizome of grey plant Radix Cynanchi Paniculati of dream Japonica section; Suffering, temperature.Return liver, stomach warp; Dispelling wind and removing obstruction in the collateral is arranged, pain relieving, antipruritic, the effect of removing toxic substances and promoting subsidence of swelling; Be used for the treatment of rheumatic arthralgia clinically, abdominal pain, toothache, the tumbling down pain of injury, eczema, rubella pruritus, stubborn dermatitis, diseases such as venom.
Cortex Phellodendri: natural plants Chinese medicine, remove the bark of crust for the yellow tiller of cloud savoury herb or Clausena lansium (Lour.) Skeels number; Hardship, cold.Go into kidney, bladder, large intestine channel; Heat clearing and damp drying is arranged, eliminating fire and detoxication, the effect of clearind deficient heat; Be used for damp-heat dysentery, jaundice due to damp-heat clinically, the puckery pain of dribbling urination, leucorrhea with red and white discharge, pudendum swells and ache, sufficient swelling and pain in knee, it is soft unable to wither, pathopyretic ulcer, eczema, fever due to yin deficiency, diseases such as emission.
Borneolum Syntheticum: be the process of resin product of Dipterocarpaceae plant Borneolum Syntheticum; Hot, bitter, be slightly cold.Go into the heart, spleen, lung meridian; There is analepsia to have one's ideas straightened out, the effect of clearing away heat to alleviate pain.Be used for the treatment of the coma convulsion clinically and faint, skin infection scabies, aphtha, laryngalgia, diseases such as ophthalmic.
Azone: colourless extremely little yellow transparent oily liquids, be dissolved in organic solvents such as ethanol, ether, cyclohexane, petroleum ether, water insoluble, mainly, have potentiation significantly after the interpolation as permeation-promoter.
Film former PVP: a kind of water soluble polymer resin, be white powder or clear solution, odorless, tasteless, nonhygroscopic, water soluble, ethanol and anhydrous alcohols have good caking property, hygroscopicity, film property and surface activity.
Above Fructus Cnidii has warming the kidney to invigorate YANG, and the effect of removing dampness and killing parasites is sterile to the woman, and pudendum pruritus due to damp pathogen etc. has good curative effect; Radix Sophorae Flavescentis has heat clearing and damp drying, the effect of wind dispelling insecticide, and to leucorrhea with red and white discharge, pudendal pruritus, whole body pruritus due to wind pathogen, the scabies stubborn dermatitis has good curative effect; This two flavors medicine share then and brings out the best in each other, and the effect high-tensile strength is grand, is monarch drug altogether.Radix Et Rhizoma Rhei can be gone the water expectorant, and the detumescence of erosion pus pushes away Chen Zhixin, and is red white to dysentery, the stomachache pain in the abdomen, and the jaundice edema has good curative effect; The Radix Astragali has the effect of invigorating QI to consolidate the body surface resistance, hidroschesis detoxification, granulation promoting, diuresis, detumescent; Radix Angelicae Sinensis has tonifying blood and regulating menstruation, the effect of promoting blood circulation and stopping pain; This three flavors medicine can be assisted the Fructus Cnidii removing dampness and killing parasites, helps the Radix Sophorae Flavescentis wind dispelling insecticide, is combined into ministerial drug.Folium Artemisiae Argyi has back the exhausted Yuanyang of hanging down, and logical 12 warps are walked three the moon, the blood of regulating the flow of vital energy, and by cold-damp, all blood is ended, warming middle-JIAO dissipating depression of QI, the effect that regulating menstruation is antiabortive in warm uterus; Radix Cynanchi Paniculati has dispelling wind and removing obstruction in the collateral, and pain relieving is antipruritic, the effect of removing toxic substances and promoting subsidence of swelling; Cortex Phellodendri has heat clearing and damp drying, eliminating fire and detoxication, the effect of clearind deficient heat; Treating blood disorders of regulating the flow of vital energy of this three flavor medicine, an antalgesic-antipruritic, an eliminating fire and detoxication is adjuvant drug altogether.Borneolum Syntheticum has analepsia to have one's ideas straightened out, and the effect of clearing away heat to alleviate pain is messenger drug.So employed composition of raw materials meets traditional Chinese medical science combination formula theory among the present invention, and has the YAOJING of choosing, coordinate mutually between each single medicinal material, realized the characteristics of taking into account of whole structure and partial result; The additives that added make the present invention be different from traditional form of Chinese drug, thereby reach better therapeutic.
This medicine is the milky foam-like material, uses and form transparent film rapidly behind the affected part.
Two. be used for the preparation method of the clean medicine of woman of gynaecological inflammation disease
1. the preparation method of the clean medicine of woman may further comprise the steps:
(1) raw material is mixed in proportion, adds 10～20 times of decoctings and boiled 3～4 hours;
(2) after the filtration, medicinal residues are added 8～10 times of water decocted again 1～2 hour;
(3) merging filtrate, concentrated filtrate;
(4) add adjuvant again by formula proportion;
(5) then through stirring, filtration, canned and add gas disposal, promptly get described treatment gynaecological inflammation disease medicine.
Described raw material and adjuvant, its composition and proportioning are seen the explanation of the clean medicine of aforesaid woman.
2. the specific embodiment of the preparation method of the clean medicine of woman:
The preparation method one of the clean medicine of example 1. woman
(1) weighing (weight portion): 60 parts of Fructus Cnidiis, 55 parts of Radix Sophorae Flavescentiss, 20 parts of Radix Et Rhizoma Rhei, 50 parts of the Radixs Astragali, 30 parts of Radix Angelicae Sinensis, 45 parts of Folium Artemisiae Argyis, 40 parts of Radix Cynanchi Paniculatis, 40 parts of Cortex Phellodendris, 6 parts of Borneolum Syntheticums, 4 parts of azones.
(2) preparation: the raw material that takes by weighing is mixed in proportion, adds 15 times of decoctings and boiled 3.5 hours; After the filtration, medicinal residues are added 9 times of water arrows boiled merging filtrate, concentrated filtrate 1.5 hours; Add 0.5 part of surfactant benzene benzyl bromine ammonium, film former PVP5 part, 6 parts of quaternized vinylpyrrolidones, 3 parts in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium; Through stirring, filter then, canned, aerating promptly gets the clean medicine of woman.
The preparation method two of the clean medicine of example 2. woman
(1) weighing (weight portion): 80 parts of Fructus Cnidiis, 75 parts of Radix Sophorae Flavescentiss, 30 parts of Radix Et Rhizoma Rhei, 60 parts of the Radixs Astragali, 50 parts of Radix Angelicae Sinensis, 60 parts of Folium Artemisiae Argyis, 60 parts of Radix Cynanchi Paniculatis, 60 parts of Cortex Phellodendris, 8 parts of Borneolum Syntheticums, 5 parts of azones.
(2) preparation: the raw material that takes by weighing is mixed in proportion, adds 20 times of decoctings and boiled 4 hours; After the filtration, medicinal residues are added 10 times of water arrows boiled merging filtrate 2 hours, concentrated filtrate, add 0.8 part of surfactant benzene benzyl bromine ammonium, film former PVP5 part, 8 parts of quaternized vinylpyrrolidones, 5 parts in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium, through stirring, filter, canned, aerating promptly gets the clean medicine of woman.
The preparation method three of the clean medicine of example 3. woman
(1) weighing (weight portion): 40 parts of Fructus Cnidiis, 40 parts of Radix Sophorae Flavescentiss, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Radix Angelicae Sinensis, 30 parts of Folium Artemisiae Argyis, 20 parts of Radix Cynanchi Paniculatis, 30 parts of Cortex Phellodendris, 1 part of Borneolum Syntheticum, 2 parts of azones.
(2) preparation: the raw material that takes by weighing is mixed in proportion, adds 20 times of decoctings and boiled 4 hours; After the filtration, medicinal residues are added 10 times of water arrows boiled merging filtrate 2 hours, concentrated filtrate, add 0.2 part of surfactant benzene benzyl bromine ammonium, film former PVP3 part, 2 parts of quaternized vinylpyrrolidones, 1 part in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium, through stirring, filter, canned, aerating promptly gets the clean medicine of woman.
The preparation method four of the clean medicine of example 4. woman
(1) weighing (weight portion): 70 parts of Fructus Cnidiis, 60 parts of Radix Sophorae Flavescentiss, 25 parts of Radix Et Rhizoma Rhei, 40 parts of Radix Angelicae Sinensis, 55 parts of Folium Artemisiae Argyis, 50 parts of Radix Cynanchi Paniculatis, 45 parts of Cortex Phellodendris, 4.5 parts of Borneolum Syntheticums, 3.5 parts of azones.
(2) preparation: the raw material that takes by weighing is mixed in proportion, adds 20 times of decoctings and boiled 4 hours; After the filtration, medicinal residues are added 10 times of water arrows boiled merging filtrate 2 hours, concentrated filtrate, add 0.2 part of surfactant benzene benzyl bromine ammonium, film former PVP7 part, 2 parts of quaternized vinylpyrrolidones, 4.5 parts in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium, through stirring, filter, canned, aerating promptly gets the clean medicine of woman.
Three. the using method of the clean medicine of woman
The using method of this medicine is very simple, and is specific as follows: with warm water cleaning pudendum place, then this medicine is sprayed or the inflammation part that is infused in the patient gets final product, every night once, one bottle is a course of treatment.This medicine can be treated can form the medical releasing film that can slowly discharge drug effect rapidly after foam leaves in inflammation part moment generation fine foam, and tight obedient in inflammation part, thereby can reach better therapeutic.
Four. the curative effect of the clean medicine of woman
By the present invention having been carried out system's clinical observation of 903 examples, prove that the present invention has good curative effect.In the 903 routine cases, select cervicitis and vaginitis 124 examples altogether, trichomonal vaginitis 225 examples, cervical erosion 161 examples, pudendal pruritus, leukorrhagia 393 examples, wherein minimum 17 years old of age, maximum 53 years old, the course of disease is the shortest 30 days, and was the longest 18 months.
Therapeutic Method: with warm water cleaning pudendum place, then this medicine is sprayed or is infused in patient's inflammation part, every night once, one bottle is a course of treatment.
Curative effect judging standard:
Recurrence: recur after one month after the drug withdrawal;
Effectively: medication sx two courses of treatment, one of reuse gets nowhere the course of treatment;
Produce effects: a medication transference cure course of treatment;
Recovery from illness: two to six courses of treatment of medication, recover normal person.
Therapeutic outcome: simple property cervicitis produce effects 45 people, account for 93.75%, effective 3 people account for 6.25%; Cervicitis merges vaginitis produce effects 61 people, accounts for 80.3%, and effective 15 people account for 19.7%.Trichomonal vaginitis 209 people that fully recover account for 92.9%, and effective 16 people account for 7.1%, recur 22 people, account for 9.8%.Cervical erosion 145 people that fully recover account for 90.1%, and effective 16 people account for 9.9%.Pudendal pruritus, leukorrhagia 362 people that fully recover account for 92.1%, and effective 31 people account for 7.9%.
Clinical observation result illustrates that medicine provided by the invention has good effect really for the treatment gynecological inflammation.
Claims (6)
1. treat the gynaecological inflammation disease medicine for one kind, it is characterized in that by weight its combination formula comprises following raw material: 40～80 parts of Fructus Cnidiis, 40～75 parts of Radix Sophorae Flavescentiss, 10～30 parts of Radix Et Rhizoma Rhei, 0～60 part of the Radix Astragali, 10～50 parts of Radix Angelicae Sinensis, 30～60 parts of Folium Artemisiae Argyis, 20～60 parts of Radix Cynanchi Paniculatis, 30～60 parts of Cortex Phellodendris, 1～8 part of Borneolum Syntheticum, 2～5 parts of azones.
2. treatment gynaecological inflammation disease medicine according to claim 1, it is characterized in that by weight, its combination formula also comprises the i.e. four kinds of chemical polymer substances of adjuvant: 0.2～0.8 part of surfactant benzene benzyl bromine ammonium, film former PVP3～8 part, 2～8 parts of quaternized vinylpyrrolidones, 1～5 part in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium.
3. treatment gynaecological inflammation disease medicine according to claim 1 is characterized in that by weight its combination formula is made up of following raw material: 60 parts of Fructus Cnidiis, 55 parts of Radix Sophorae Flavescentiss, 20 parts of Radix Et Rhizoma Rhei, 50 parts of the Radixs Astragali, 30 parts of Radix Angelicae Sinensis, 45 parts of Folium Artemisiae Argyis, 40 parts of Radix Cynanchi Paniculatis, 40 parts of Cortex Phellodendris, 6 parts of Borneolum Syntheticums, 4 parts of azones, 0.5 part of surfactant benzene benzyl bromine ammonium, film former PVP5 part, 6 parts of quaternized vinylpyrrolidones, 3 parts in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium.
4. preparation method for the treatment of the gynaecological inflammation disease medicine is characterized in that may further comprise the steps:
(1) raw material is mixed, add 10～20 times of decoctings and boiled 3～4 hours; By weight, described raw material is 40～80 parts of Fructus Cnidiis, 40～75 parts of Radix Sophorae Flavescentiss, 10～30 parts of Radix Et Rhizoma Rhei, 0～60 part of the Radix Astragali, 10～50 parts of Radix Angelicae Sinensis, 30～60 parts of Folium Artemisiae Argyis, 20～60 parts of Radix Cynanchi Paniculatis, 30～60 parts of Cortex Phellodendris, 1～8 part of Borneolum Syntheticum, 2～5 parts of azones;
(2) after the filtration, medicinal residues are added 8～10 times of water decocted again 1～2 hour;
(3) merging filtrate, concentrated filtrate;
(4) by weight, add adjuvant again, that is: surfactant benzene benzyl bromine ammonium is 0.2～0.8 part, film former PVP3～8 part, 2～8 parts of quaternized vinylpyrrolidones, 1～5 part in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium;
(5) then through stirring, filtration, canned and add gas disposal, promptly get described treatment gynaecological inflammation disease medicine.
5. the preparation method of treatment gynaecological inflammation disease medicine according to claim 4 is characterized in that by weight, and the combination formula of described medicine is made up of following raw material: 60 parts of Fructus Cnidiis, 55 parts of Radix Sophorae Flavescentiss, 20 parts of Radix Et Rhizoma Rhei, 50 parts of the Radixs Astragali, 30 parts of Radix Angelicae Sinensis, 45 parts of Folium Artemisiae Argyis, 40 parts of Radix Cynanchi Paniculatis, 40 parts of Cortex Phellodendris, 6 parts of Borneolum Syntheticums, 4 parts of azones, 0.5 part of surfactant benzene benzyl bromine ammonium, film former PVP5 part, 6 parts of quaternized vinylpyrrolidones, 3 parts in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium.
6. the preparation method of treatment gynaecological inflammation disease medicine according to claim 4 is characterized in that: raw material adds 15 times of decoctings and boiled 3.5 hours after mixing; After the filtration, medicinal residues are added 9 times of decoctings boiled 1.5 hours; Merging filtrate, concentrated filtrate; By weight, add 0.5 part of surfactant benzene benzyl bromine ammonium again, film former PVP5 part, 6 parts of quaternized vinylpyrrolidones, 3 parts in emulsifying agent aliphatic alcohol polyethenoxy (10) ether hydroxy acid sodium; Through stirring, filtration, canned and add gas disposal, promptly get described treatment gynaecological inflammation disease medicine then.
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| EP2343065A4 (en) * | 2008-09-11 | 2012-09-19 | Qingdao Qiyuan Bio Technologies Co Ltd | The pharmaceutical composition containing ferulic acid and matrine compounds, the preparation and the use thereof |
| CN103623047A (en) * | 2013-12-13 | 2014-03-12 | 吴红霞 | Preparation method of gynecological external use medicament |
| CN109172705A (en) * | 2018-06-26 | 2019-01-11 | 佛山市可悦卫生用品科技有限公司 | A kind of women's health health Chinese medicine nursing pad and preparation method thereof |
| CN110680855B (en) * | 2019-11-25 | 2022-06-07 | 哈尔滨欧替药业有限公司 | Vaginal expansion suppository containing probiotics and traditional Chinese medicine composition and preparation method thereof |
| CN112263621A (en) * | 2020-11-06 | 2021-01-26 | 杭州纯源生物科技有限公司 | Preparation method of bacteriostatic liquid for private care |
| CN112972322A (en) * | 2020-12-28 | 2021-06-18 | 常栓 | External shower gel for preventing and treating fungal skin diseases and gynecological diseases based on traditional Chinese medicine materials and preparation and processing method thereof |
| CN112891483A (en) * | 2021-03-19 | 2021-06-04 | 王永静 | Pregnant gynaecology and obstetrics hip bath liquid medicine and preparation method thereof |
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