CN104740458A - Pruritus treating traditional Chinese medicine composition - Google Patents

Abstract

The present invention belongs to the field of traditional Chinese medicine preparations, and relates to a pruritus treating traditional Chinese medicine composition, which is characterized in that the bulk drugs for preparing the effective components comprise, by weight, 10-30 parts of sophora flavescens ait, 10-25 parts of cortex dictamni, 5-15 parts of cortex phellodendri, 10-30 parts of atractylodes lancea, 5-10 parts of angelica dahurica, 5-15 parts of scutellaria baicalensis, 5-20 parts of cnidium monnieri, 5-15 parts of saposhnikovia divaricata, 5-15 parts of periostracum cicadae, 2-10 parts of coptis chinensis, 10-30 parts of stemona japonica, 10-30 parts of fructus kochiae, 10-25 parts of herba siegesbeckiae, 10-20 parts of lemna minor, 10-20 parts of fructus xanthii, and 0.1-2 parts of borneol. The pruritus treating traditional Chinese medicine composition of the present invention has characteristics of compatibility of various drugs and complement effect, has effects of patient body function regulating, blood nourishing, qi benefitting, endogenous wind-evil treating, itching relieving, efficacy synergy effect, and no obvious side effect, and provides effects of pathogen eliminating, healthy qi supporting and itching relieving for pruritus.

Description

A kind of Chinese medicine composition for the treatment of skin pruritus

Technical field

The present invention relates to a kind of medicine for the treatment of skin pruritus, particularly relating to a kind of take vegetable Chinese herbal medicine as the Chinese medicine composition of the treatment skin pruritus that raw material is made.

Background technology

Skin pruritus is the commonly encountered diseases of department of dermatologry, and main manifestations is for only having skin pruritus and without constitutional skin lesion, and treatment relative difficulty, easily recurs.Pruritus is one of main subjective symptoms of multiple dermatosis, and pruritic skin mainly comprises skin pruritus, neurodermatitis, papular urticaria, chronic eczema, tinea manus and pedis, scabies, prurigo nodularis and dermatitis aestivale etc.Because the itching skin disease cause of disease is complicated, inducement is more, is department of dermatologry common clinical, frequently-occurring disease, account for Dermatology Outpatient Department patient's more than 80%, bring great misery to patient, quality of life obviously declines, in the prior art, the Western medicine for the treatment of skin pruritus, generally all adopts and applies medicinal lotion or ointment or oral medicine, although drug effect is significantly rapid containing the outer of artificial hormone, alleviate pruritis to a certain extent, but be easier to tolerance, relapse rate is high, and normal with certain side effect.Particularly easily there is the phenomenons such as pigementation, telangiectasis and keratodermatitis thicken in outer agents area of wiping, and clinical efficacy is still unsatisfactory.The Chinese medicine for oral administration of some treatment skin pruritus, although determined curative effect after taking, relapse rate are low, it is slowly effective.

Object of the present invention is exactly the technical deficiency existed for existing treatment skin pruritus disease, provides a kind of Chinese medicine composition of special-purpose for treating skin itching, cheap, effectively can effect a radical cure skin pruritus, make it no longer recur.

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of skin pruritus, it is characterized in that, the crude drug making effective ingredient by following weight parts is: Radix Sophorae Flavescentis 10-30 part, Cortex Dictamni 10-25 part, Cortex Phellodendri 5-15 part, Rhizoma Atractylodis 10-30 part, Radix Angelicae Dahuricae 5-10 part, Radix Scutellariae 5-15 part, Fructus Cnidii 5-20 part, Radix Saposhnikoviae 5-15 part, Periostracum Cicadae 5-15 part, Rhizoma Coptidis 2-10 part, Radix Stemonae 10-30 part, Fructus Kochiae 10-30 part Herba Siegesbeckiae 10-25 part, Herba Spirodelae 10-20 part, Fructus Xanthii 10-20 part, Borneolum Syntheticum 0.1-2 part.

The Chinese medicine composition of the Cutaneous pruritus of above-mentioned treatment, makes unguentum or liquid preparation according to existing pharmaceutical manufacturing.

Pharmacology analysis

Radix Sophorae Flavescentis: heat clearing away, dampness, parasite killing.Control toxic-heat and blood stasis, discharging fresh blood stool, jaundice, leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, mange malignant boil, erosion of vulva pruritus due to damp pathogen, scrofula, scald.

Cortex Dictamni: dispel the wind, dampness, heat clearing away, removing toxic substances.Control wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.

Cortex Phellodendri: heat clearing away, dampness, pathogenic fire purging, removing toxic substances.Control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice ， flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, leucorrhea with red and white discharge, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.

Rhizoma Atractylodis: spleen invigorating, dampness, resolving depression, wards off dirty.Control wet Sheng and be stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, and seasonal epidemic pathogens is caught a cold, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.

The Radix Angelicae Dahuricae: dispel the wind, dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.

Radix Scutellariae: removing the relative excess fire, except damp and hot, hemostasis, antiabortive.Control high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tell, be defeated in battle, collapse, leak, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.

Fructus Cnidii: warming the kidney to activate YANG, dispels the wind, dampness, parasite killing.Control impotence in male, scrotum pruritus due to damp pathogen, woman's leukorrhagia pudendal pruritus, cold uterus is infertile, rheumatic arthralgia, scabies eczema.

Radix Saposhnikoviae: deliver, dispels the wind, and victory is wet, pain relieving.Control affection of exogenous wind-cold, headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint is ached, and extremity contraction is anxious, tetanus.

Periostracum Cicadae: loose wind heat, lung qi dispersing, determines convulsion.Control affection due to external wind and heat, cough hoarseness, measles is sent out not smooth thoroughly, rubella pruritus, pediatric epilepsy scared, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.

Rhizoma Coptidis: pathogenic fire purging, dampness, removing toxic substances, parasite killing.Row pyretic toxicity when controlling, typhoid fever, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, and lung knot is pressed, and tells, is defeated in battle, hematochezia, quench one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.

The Radix Stemonae: gentle lung qi, cough-relieving, parasite killing.Control cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema.

The Fructus Kochiae: diuresis, clearing away damp-heat.Control dysuria, gonorrhea, leukorrhagia, hernia, rubella, sore, scabies, pudendum pruritus due to damp pathogen.

Herba Siegesbeckiae: remove rheumatism, strong muscles and bones, heat-clearing and toxic substances removing.For rheumatic arthralgia, apoplexy, hemiplegia, weakness of the waist and knees, ulcer swells and ache, rubella eczema pruritus etc.

Herba Spirodelae: diaphoresis, dispels the wind, row water, heat clearing away, removing toxic substances.Row calentura when controlling, macule is not saturating, wind heat urticaria, skin pruritus, edema, the difficulty in urination, skin ulcer tinea, and erysipelas is scalded.

Fructus Xanthii: loose wind, pain relieving, damp eliminating, parasite killing.Control headche due to wind-cold, nasal sinusitis, toothache, anemofrigid-damp arthralgia, limb pain twin, mange, pruritus.

Borneolum Syntheticum: logical all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain.Control apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is nebula film also, enterobiasis.

The invention has the beneficial effects as follows, all medicine compatibilities of the present invention, bring out the best in each other, the physical function of scalable patient, and nourishing blood and invigorating qi, relieves dizziness, high fever, infantile convulsions, epilepsy, etc. antipruritic, drug effect synergism, non-evident effect, serve the antipruritic effect of righting of getting rid of evils to skin pruritus.

The clinical observation for the treatment of by Chinese herbs skin pruritus of the present invention.

Physical data

Clinical observation material is totally 50 examples, wherein, male 27 example, women 23 example, age 18-30 year 8 examples, 31-40 year 9 examples, 41-50 year 15 examples, more than 50 years old 18 is routine.

Diagnostic criteria

General skin pruritus: skin is itched without determining place or general property skin pruritus by the whole body, and night attaches most importance to, xerosis cutis, and scratch is obvious;

Limitation skin pruritus: gargalesthesia is confined to a certain position of health more, affected part sees that due to long-term pruritus infiltration is plump, lichenification and eczematization;

Deficiency of YIN wind contains disease diagnosis

Primary symptom: 1, skin pruritus, becoming severe at night and/or rise one after another;

2, red tongue or partially red, Artemusia lactiflora Wall. or flower stripping;

3, skin is scorching hot and/or dry.

Secondary disease: 1, scratch is innumerable or in lichenification;

2, dysphoria with smothery sensation;

3, dry throat and mouth;

4, difficulty in defecation;

5, stringy and thready pulse or stringy and thready pulse number.

Using method

Every day 3 times, Traditional Chinese medicine composition paste of the present invention or liquid preparation being applied in affected part, 15 days is a course for the treatment of, general 2-3 course for the treatment of.

Efficacy assessment standard

Clinical recovery: pruritus disappears completely, other clinical pathological changes transference cures;

Effective: pruritis disappears substantially, secondary skin obviously improves;

Effective: pruritus alleviates, meeting inducement by chance has endurable gargalesthesia, and diseased region reduces, and skin is light red or red, and secondary skin lesion makes moderate progress;

Invalid: pruritus and secondary skin lesion improve not obvious.

Efficacy result

Recovery from illness 28 example, accounts for 56%, and effective 12 examples, account for 24%, and effective 6 examples, account for 12%, and invalid 4 examples, account for 8%, total effective rate reaches 92%.

Model case

Season, man, 61 years old.Patient often feel over nearly 3 months the whole body pruritus, with two lower limb for work, when night undresses or meet wind and cold time more so, grab rear skin adularescent vestige and without welt occur, external hormones ointment gram takes a turn for the better slightly, but does not heal always.Within nearly one week, carry out gargalesthesia and increase the weight of and go to a doctor.Look into: whole body skin shows slightly dry, without former skin lesion, only has a small amount of scratch.Body of the tongue is light red, white and thin fur, stringy pulse slow.Adopt ointment of the present invention to be applied to affected part, after two weeks, during further consultation, gargalesthesia obviously alleviates.

Wang, female, 70 years old.Patient often feels whole body pruritus over nearly 2 years, autumn and winter increases the weight of.Various desensitizer, vitamin drug for oral administration etc., and external hormones ointment, poor effect.Over nearly 2 months, pruritus day by day increases the weight of, impact sleep, and agitation is not peaceful, and asthenia is indigestion and loss of appetite, is hard and dry.Look into: whole body xerosis cutis, have more scratch, partial skin is slightly plump.Body of the tongue is light red, has ecchymosis, and tongue is white, deep-thready pulse.Adopt ointment of the present invention to be applied to affected part, after one month, during further consultation, gargalesthesia obviously alleviates, and scratch reduces, and defecates modulated.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take Radix Sophorae Flavescentis 30 parts, Cortex Dictamni 25 parts, Cortex Phellodendri 15 parts, Rhizoma Atractylodis 30 parts, the Radix Angelicae Dahuricae 10 parts, Radix Scutellariae 15 parts, Fructus Cnidii 20 parts, Radix Saposhnikoviae 15 parts, Periostracum Cicadae 15 parts, Rhizoma Coptidis 10 parts, the Radix Stemonae 30 parts, the Fructus Kochiae 30 parts of Herba Siegesbeckiae 25 parts, 20 parts, Herba Spirodelae, Fructus Xanthii 20 parts, Borneolum Syntheticum 2 parts, makes unguentum or liquid preparation according to existing pharmaceutical methods.

Embodiment 2

Preferably take Radix Sophorae Flavescentis 20 parts, Cortex Dictamni 15 parts, Cortex Phellodendri 10 parts, Rhizoma Atractylodis 20 parts, the Radix Angelicae Dahuricae 8 parts, Radix Scutellariae 10 parts, Fructus Cnidii 15 parts, Radix Saposhnikoviae 10 parts, Periostracum Cicadae 15 parts, Rhizoma Coptidis 8 parts, the Radix Stemonae 20 parts, the Fructus Kochiae 20 parts of Herba Siegesbeckiae 20 parts, 15 parts, Herba Spirodelae, Fructus Xanthii 15 parts, Borneolum Syntheticum 1 part, makes unguentum or liquid preparation according to existing pharmaceutical methods.

Embodiment 3

Preferably take Radix Sophorae Flavescentis 10 parts further, Cortex Dictamni 10 parts, Cortex Phellodendri 5 parts, Rhizoma Atractylodis 10 parts, the Radix Angelicae Dahuricae 5 parts, Radix Scutellariae 5 parts, Fructus Cnidii 5 parts, Radix Saposhnikoviae 5 parts, Periostracum Cicadae 5 parts, Rhizoma Coptidis 2 parts, the Radix Stemonae 10 parts, the Fructus Kochiae 10 parts of Herba Siegesbeckiae 10 parts, 10 parts, Herba Spirodelae, Fructus Xanthii 10 parts, Borneolum Syntheticum 0.5 part, makes unguentum or liquid preparation according to existing pharmaceutical methods.

Claims (4)

1. treat a Chinese medicine composition for skin pruritus, it is characterized in that, the crude drug making effective ingredient by following weight parts is: Radix Sophorae Flavescentis 10-30 part, Cortex Dictamni 10-25 part, Cortex Phellodendri 5-15 part, Rhizoma Atractylodis 10-30 part, Radix Angelicae Dahuricae 5-10 part, Radix Scutellariae 5-15 part, Fructus Cnidii 5-20 part, Radix Saposhnikoviae 5-15 part, Periostracum Cicadae 5-15 part, Rhizoma Coptidis 2-10 part, Radix Stemonae 10-30 part, Fructus Kochiae 10-30 Fen ， Herba Siegesbeckiae 10-25 part, Herba Spirodelae 10-20 part, Fructus Xanthii 10-20 part, Borneolum Syntheticum 0.1-2 part.

2. a kind of Chinese medicine composition for the treatment of skin pruritus according to claim 1, it is characterized in that, the crude drug making effective ingredient by following weight parts is: Radix Sophorae Flavescentis 30 parts, Cortex Dictamni 25 parts, Cortex Phellodendri 15 parts, Rhizoma Atractylodis 30 parts, the Radix Angelicae Dahuricae 10 parts, Radix Scutellariae 15 parts, Fructus Cnidii 20 parts, Radix Saposhnikoviae 15 parts, Periostracum Cicadae 15 parts, Rhizoma Coptidis 10 parts, the Radix Stemonae 30 parts, the Fructus Kochiae 30 Fen ， Herba Siegesbeckiae 25 parts, 20 parts, Herba Spirodelae, Fructus Xanthii 20 parts, Borneolum Syntheticum 2 parts.

3. a kind of Chinese medicine composition for the treatment of skin pruritus according to claim 1, it is characterized in that, the crude drug making effective ingredient by following weight parts is: Radix Sophorae Flavescentis 20 parts, Cortex Dictamni 15 parts, Cortex Phellodendri 10 parts, Rhizoma Atractylodis 20 parts, the Radix Angelicae Dahuricae 8 parts, Radix Scutellariae 10 parts, Fructus Cnidii 15 parts, Radix Saposhnikoviae 10 parts, Periostracum Cicadae 15 parts, Rhizoma Coptidis 8 parts, the Radix Stemonae 20 parts, the Fructus Kochiae 20 Fen ， Herba Siegesbeckiae 20 parts, 15 parts, Herba Spirodelae, Fructus Xanthii 15 parts, Borneolum Syntheticum 1 part.

4. a kind of Chinese medicine composition for the treatment of skin pruritus according to claim 1, it is characterized in that, the crude drug making effective ingredient by following weight parts is: Radix Sophorae Flavescentis 10 parts, Cortex Dictamni 10 parts, Cortex Phellodendri 5 parts, Rhizoma Atractylodis 10 parts, the Radix Angelicae Dahuricae 5 parts, Radix Scutellariae 5 parts, Fructus Cnidii 5 parts, Radix Saposhnikoviae 5 parts, Periostracum Cicadae 5 parts, Rhizoma Coptidis 2 parts, the Radix Stemonae 10 parts, the Fructus Kochiae 10 Fen ， Herba Siegesbeckiae 10 parts, 10 parts, Herba Spirodelae, Fructus Xanthii 10 parts, Borneolum Syntheticum 0.5 part.