CN104721582A

CN104721582A - Medicine for treating hypomenorrhea due to deficiency of kidney and preparation method thereof

Info

Publication number: CN104721582A
Application number: CN201510138147.1A
Authority: CN
Inventors: 李佃场
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-03-27
Filing date: 2015-03-27
Publication date: 2015-06-24

Abstract

The invention discloses a medicine for treating hypomenorrhea due to the deficiency of the kidney and a preparation method thereof. The medicine is prepared from the following medicinal raw materials: dried human placenta, eucommia bark, flastem milkvetch seeds, tokay, hairy antlers, sea horses, ursine seal testes and penes, prepared rhizome of adhesive rehmannias, dried longan pulp, cochinchinese asparagus roots, noble dendrobium stems, manyflower solomonseal rhizomes, barbary wolfberry fruits, glossy privet fruit, tortoise shells, rose flowers, gaulis aristolochiae, Danshen roots, twotooth achyranthes roots, suberect spatholobus stems, goat or sheep testes, dragonflies, Elaphurus Davidianus Milne-Edwards, greywhitehair raspberry fruits, air bladders of yellow croakers, freshwater sponge, wild groundnut seeds, cushaw stems, dahurian rose fruits and ford metalleaf roots. The medicine has the functions of nourishing the kidney, strengthening the essence, nourishing blood and regulating menstruation and is mainly used for treating hypomenorrhea due to the deficiency of the kidney. The medicine is prepared by integrating the concept of wholism with the treatment based on syndrome differentiation, can be used for improving the overall function, state and immunity of the human body, regulating qi and blood and improving the metabolism of blood, is targeted at hypomenorrhea due to the deficiency of the kidney, can take effect on the diseased part directly, is short in course of treatment, causes less adverse reactions, is safe and efficient, can be used selectively according to different clinical symptoms, can be applied conveniently and can be easily accepted by patients, and patients can not become resistant to the medicine.

Description

A kind ofly treat medicine of renal deficiency type hypomenorrhea and preparation method thereof

Technical field

The present invention relates to the medicinal preparation containing deriving from plant, animal or raw mineral materials, particularly a kind ofly treating medicine of renal deficiency type hypomenorrhea and preparation method thereof.

Background technology

Menstrual cycle is normal, through measuring obvious minimizing, even drop is namely clean, or shortening menstrual period less than two days, also lacking person, be called " hypomenorrhea " through amount.Also known as " a small amount of menses and menstruating unsmoothly ", " very few through measuring ", " through row pettiness ".

Namely only etiology and pathology: 1, menstrual cycle is normal, through measuring obvious minimizing, even drop be the diagnostic point of primary disease, often and delayed menstrual cycle seeing.2, some medicine can cause hypomenorrhea, as contraceptive, treatment chlorpromazine, antineoplastic agent, treatment endometriosis class medicine (as tamoxifen, danazol, nemestran etc.), in addition the medicine such as Radix Tripterygii Wilfordii tablet, bromocriptine also can cause spanomenorrhea, faces when examining and should inquire relevant medical history in detail.3, repeatedly artificial abortion operation or operation roughly, damage uterus basal layer inner membrance or uterine cavity are adhered, and all can cause hypomenorrhea, therefore also need inquiry abortion situation.Postpartum hemorrhage first shows hypomenorrhea sometimes, then amenorrhea.4, the situation of the simple hypomenorrhea of anovulatory functional bleeding is more rare, is the tendency of anovulation amenorrhea sometimes.Polycystic ovarian syndrome also shows hypomenorrhea, often accompanies delayed menstrual cycle, and body weight increases, and then hears warp.Premature ovarian failure person first shows hypomenorrhea, amenorrhea then.5, first hypomenorrhea companion delayed menstrual cycle person should get rid of miscarriage or ectopic pregnancy, and urine, blood pregnancy tests and B ultrasonic all can be differentiated.

Differential Diagnosis: 1, carefully inquire medical history: menstrual history in the past, whether menolipsis history, childbearing history, whether abortion's history, whether chronic disease or clothes affect the pharmacohistory of menstruation, whether gynaecopathia history etc.2, gynecologial examination: inside and outside genitals is with or without special abnormality situation, if be polycystic ovarian syndrome person, bilateral ovaries slightly increases; Endometriosis person side or bilateral ovaries increase, and in cystic, be adhered with uterus, body of uterus fixes hypsokinesis, isthmus uteri can be laid one's hand on and tuberosity.3, Visual quality (or both transvaginal ultrasonography): diagnosis miscarriage, ectopic pregnancy, endometriosis and polycystic ovarian syndrome, uterine cavity are adhered etc. and have reference value.4, blood Endocrinological inspection: inspection item, as T, PRL, FSH, LH, E2, P etc., has reference value disastrously to see relevant chapters and sections to diagnosis of polycystic ovary syndrome, premature ovarian failure, androgen-induced sterile rats etc.).As taking hormone medicine, blood endocrine can be affected and report the result.

Chinese medicine is thought, menstrual cycle is normal, and be obviously less than previously through measuring, menstrual period were less than 2 days, even drop and clean person, claims " hypomenorrhea ", also known as " a small amount of menses and menstruating unsmoothly, very few through measuring ".

Etiology and pathogenesis: dominant mechanism is damage of essence insufficiency of blood, insufficiency of vital energy and blood is appointed in punching, or cold coagulation stasis blocking, and punching appoints QI and blood not smooth, and sea of blood spill-over is few and cause.Common typing is suffered from a deficiency of the kidney, blood deficiency, cold in blood and blood stasis.One, suffer from a deficiency of the kidney: natural endowment is not enough, or exhaustion due to sexual indulgence prolonged illness, damage kidney qi, or have an abortion time and again, wound essence consumption gas, deficiency of the kidney, deficiency of kidney-QI, virtual loss is appointed in punching, and sea of blood spill-over is few, then causes Hypomenorrhea.Two, blood deficiency: number is hindered in blood, serious disease prolonged illness, deficiency of nutrient QI and blood, or improper diet and overtiredness, excessive thinking, damage temper, insufficiency of the spleenization source is not enough, qi-blood deficiency of chong-ren, and sea of blood spill-over is few, causes through row amount few.Three, cold in blood: in puerperal in menstrual period, experience cold-evil, or eating cold and uncooked food excessively, cold-evil lies prostrate and appoints in punching, and blood is for cold stagnant, and run not smooth, sea of blood spill-over is few, causes through row amount few.Four, blood stasis: puerperal in menstrual period, when remaining blood is unclean, internal injury caused by excess of seven emotions, qi depression to blood stasis, or experience pathogen, evil and blood agglomeration, the stagnant punching of the stasis of blood is appointed, and QI-blood circulation is not smooth, and sea of blood spill-over is few, causes through row amount few.

Differentiation of symptoms and signs for classification of syndrome: one, renal deficiency type main syndromes: few through carrying out amount, namely clean within the next few days, or namely drop stops, and color is light dim, and matter is rare, waist soreness, dizziness and tinnitus, frequent micturition, light red tongue, thin fur, deep-thready pulse.Two, blood-deficiency type main syndromes: few through carrying out amount, namely clean within the next few days, or namely drop stops, and light red through color, matter is rare, dizziness and blurred vision, palpitation and insomnia, and skin does not moisten, shallow complexion, light red tongue, thin fur, thready pulse without strength.Three, blood-cold type main syndromes: few through row amount, color is dim red, cold and pain in the lower abdomen, pain alleviated while getting warmth, aversion to cold and cold limbs, and complexion is bluish white, and tongue is dim, and tongue is white, deep and tense pulse.Four, blood stasis type main syndromes: puckery few through row, color purple is black has block, lower abdomen twinge tenderness, alleviation of pain after under clot, or distending pain in the chest and hypochondrium, and purplish tongue is dim, or has the purple point of ecchymosis, and hesitant pulse is strong.

Western medical treatment hypomenorrhea selects hormone, Progesterone, antibiotic etc, and types of drugs is less, and therapeutic scheme limits to, and the course for the treatment of is longer, brings certain psychological burden and stress etc. to patient.Clinical market needs one effectively can treat hypomenorrhea, and untoward reaction is less, and the new drug of short treating period is to meet clinical demand.

Chinese medicine hypomenorrhea, with a long history, through continuous investigation and the discussion of ancient Chinese medicine doctor, put into practice by diagnosis and treatment, have accumulated many effective treatment sides medicine, for research today and treatment hypomenorrhea provide example.Chinese medicine utilizes Traditional Chinese medical theory, payes attention to the combination at Overall View and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, is improving animal economy functional condition, improves overall immunity, regulate QI and blood, while improving plasma metabolism, for different clinical symptoms, selectivity medication, targeting is comparatively strong, and drug effect is gone directly focus, short treating period, untoward reaction is few, not easily produces drug resistance, safely, effectively, cost price is low, and route of administration is convenient, patient is easy to accept, and can carry out market development, meet clinical demand.

Summary of the invention

Technical problem to be solved by this invention is, provides one and has the kidney invigorating and essence nourishing, and effect of nourishing blood for regulating menstruation cures mainly the medicine of hypomenorrhea nephrasthenia syndrome; The present invention utilizes Traditional Chinese medical theory, payes attention to the combination at Overall View and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, is improving animal economy functional condition, improve overall immunity, regulate QI and blood, while improving plasma metabolism, for different clinical symptoms, selectivity medication, targeting is stronger, drug effect is gone directly focus, short treating period, and untoward reaction is few, not easily produce drug resistance, safely, effectively, cost price is low, route of administration is convenient, and patient is easy to accept.

For solving the problems of the technologies described above, the invention provides a kind of medicine for the treatment of hypomenorrhea nephrasthenia syndrome, wherein, described medicine comprises following raw medicinal material: Placenta Hominis, the Cortex Eucommiae, Semen Astragali Complanati, Gecko, Cornu Cervi Pantotrichum, Hippocampus, Testis et penis callorhini, Radix Rehmanniae Preparata, Arillus Longan, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati, Fructus Lycii, Fructus Ligustri Lucidi, Carapax Et Plastrum Testudinis, Flos Rosae Rugosae, Herba Aristolochiae, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Caulis Spatholobi, Testis Caprae seu Ovis, Aeschna melanictera, Carnis Elaphuri davidiani, Fructus rubi tephrodis, Air Bladder pseudosciaenae seu Acipenser, Spongilla, Semen glycines sojae, Caulis Cucurbitae, rose hip, Radix Phyllagathis fordii.

In described medicine, the ratio of weight and number of each raw medicinal material is: Placenta Hominis 10-23 weight portion, Cortex Eucommiae 10-20 weight portion, Semen Astragali Complanati 15-22 weight portion, Gecko 10-19 weight portion, Cornu Cervi Pantotrichum 12-26 weight portion, Hippocampus 10-18 weight portion, Testis et penis callorhini 10-20 weight portion, Radix Rehmanniae Preparata 13-24 weight portion, Arillus Longan 15-27 weight portion, Radix Asparagi 10-20 weight portion, Herba Dendrobii 14-25 weight portion, Rhizoma Polygonati 10-20 weight portion, Fructus Lycii 12-20 weight portion, Fructus Ligustri Lucidi 12-26 weight portion, Carapax Et Plastrum Testudinis 10-18 weight portion, Flos Rosae Rugosae 15-30 weight portion, Herba Aristolochiae 13-27 weight portion, Radix Salviae Miltiorrhizae 10-24 weight portion, Radix Achyranthis Bidentatae 12-24 weight portion, Caulis Spatholobi 10-20 weight portion, Testis Caprae seu Ovis 10-18 weight portion, Aeschna melanictera 10-18 weight portion, Carnis Elaphuri davidiani 10-20 weight portion, Fructus rubi tephrodis 12-18 weight portion, Air Bladder pseudosciaenae seu Acipenser 10-24 weight portion, Spongilla 12-25 weight portion, Semen glycines sojae 10-20 weight portion, Caulis Cucurbitae 14-27 weight portion, rose hip 10-23 weight portion and Radix Phyllagathis fordii 10-20 weight portion.

In described medicine, the ratio of weight and number of each raw medicinal material is: Placenta Hominis 15-23 weight portion, Cortex Eucommiae 15-20 weight portion, Semen Astragali Complanati 18-22 weight portion, Gecko 14-19 weight portion, Cornu Cervi Pantotrichum 12-20 weight portion, Hippocampus 14-18 weight portion, Testis et penis callorhini 15-20 weight portion, Radix Rehmanniae Preparata 13-20 weight portion, Arillus Longan 15-20 weight portion, Radix Asparagi 15-20 weight portion, Herba Dendrobii 14-20 weight portion, Rhizoma Polygonati 15-20 weight portion, Fructus Lycii 18-20 weight portion, Fructus Ligustri Lucidi 12-20 weight portion, Carapax Et Plastrum Testudinis 10-13 weight portion, Flos Rosae Rugosae 25-30 weight portion, Herba Aristolochiae 13-20 weight portion, Radix Salviae Miltiorrhizae 15-24 weight portion, Radix Achyranthis Bidentatae 18-24 weight portion, Caulis Spatholobi 15-20 weight portion, Testis Caprae seu Ovis 15-18 weight portion, Aeschna melanictera 14-18 weight portion, Carnis Elaphuri davidiani 15-20 weight portion, Fructus rubi tephrodis 15-18 weight portion, Air Bladder pseudosciaenae seu Acipenser 15-24 weight portion, Spongilla 12-20 weight portion, Semen glycines sojae 15-20 weight portion, Caulis Cucurbitae 14-20 weight portion, rose hip 16-23 weight portion and Radix Phyllagathis fordii 16-20 weight portion.

In described medicine, the ratio of weight and number of each raw medicinal material is: Placenta Hominis 13 weight portion, the Cortex Eucommiae 14 weight portion, Semen Astragali Complanati 15 weight portion, Gecko 10 weight portion, Cornu Cervi Pantotrichum 26 weight portion, Hippocampus 10 weight portion, Testis et penis callorhini 10 weight portion, Radix Rehmanniae Preparata 24 weight portion, Arillus Longan 27 weight portion, Radix Asparagi 12 weight portion, Herba Dendrobii 25 weight portion, Rhizoma Polygonati 12 weight portion, Fructus Lycii 14 weight portion, Fructus Ligustri Lucidi 26 weight portion, Carapax Et Plastrum Testudinis 18 weight portion, Flos Rosae Rugosae 15 weight portion, Herba Aristolochiae 27 weight portion, Radix Salviae Miltiorrhizae 12 weight portion, Radix Achyranthis Bidentatae 13 weight portion, Caulis Spatholobi 12 weight portion, Testis Caprae seu Ovis 13 weight portion, Aeschna melanictera 12 weight portion, Carnis Elaphuri davidiani 12 weight portion, Fructus rubi tephrodis 12 weight portion, Air Bladder pseudosciaenae seu Acipenser 12 weight portion, Spongilla 25 weight portion, Semen glycines sojae 14 weight portion, Caulis Cucurbitae 27 weight portion, rose hip 13 weight portion and Radix Phyllagathis fordii 14 weight portion.

In described medicine, the ratio of weight and number of each raw medicinal material is: Placenta Hominis 23 weight portion, the Cortex Eucommiae 20 weight portion, Semen Astragali Complanati 22 weight portion, Gecko 19 weight portion, Cornu Cervi Pantotrichum 20 weight portion, Hippocampus 18 weight portion, Testis et penis callorhini 20 weight portion, Radix Rehmanniae Preparata 20 weight portion, Arillus Longan 20 weight portion, Radix Asparagi 20 weight portion, Herba Dendrobii 20 weight portion, Rhizoma Polygonati 20 weight portion, Fructus Lycii 20 weight portion, Fructus Ligustri Lucidi 20 weight portion, Carapax Et Plastrum Testudinis 13 weight portion, Flos Rosae Rugosae 30 weight portion, Herba Aristolochiae 20 weight portion, Radix Salviae Miltiorrhizae 24 weight portion, Radix Achyranthis Bidentatae 24 weight portion, Caulis Spatholobi 20 weight portion, Testis Caprae seu Ovis 18 weight portion, Aeschna melanictera 18 weight portion, Carnis Elaphuri davidiani 20 weight portion, Fructus rubi tephrodis 18 weight portion, Air Bladder pseudosciaenae seu Acipenser 24 weight portion, Spongilla 20 weight portion, Semen glycines sojae 20 weight portion, Caulis Cucurbitae 20 weight portion, rose hip 23 weight portion and Radix Phyllagathis fordii 20 weight portion.

For solving the problems of the technologies described above, present invention also offers a kind of preparation method for the treatment of the medicine of hypomenorrhea, when the dosage form of described medicine is capsule, its preparation method is:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 80 ~ 90%, reflux 2 ~ 4 hours, extracts, and filters acquisition first extracting solution; It is the ethanol of 80 ~ 90% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;

3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing, obtain capsule by described capsule 's content.

When the dosage form of described medicine is oral solutions, its preparation method is:

The first step, Placenta Hominis, the Cortex Eucommiae and Semen Astragali Complanati are mixed, add relative to mixture 2 times ~ 4 times amount determining alcohol be 65% ~ 75% alcohol reflux 2 times ~ 4 times, each 2 hours ~ 3 hours, filter, filtrate merges, and reclaims ethanol, being concentrated into 80 DEG C of relative densities is the mastic of 1.20 ~ 1.22, for subsequent use;

Second step, is mixed in proportion described for residue raw medicinal material, adds relative to mixture 2 ~ 4 times of water gagings, boils 2 ~ 4 hours, and filter, being concentrated into 80 DEG C of relative densities is the mastic of 1.22 ~ 1.23;

3rd step, the described mastic mixing that the first step, second step are obtained, 65 DEG C ~ 75 DEG C reduced vacuum dryings, get dry extract powder;

4th step, is added ethanol in the described dried cream powder that the 3rd step is obtained, and obtains containing alcohol mastic, and the described alcohol content containing alcohol mastic is 65% ~ 70%; Carry out chilling treatment, precipitation process, filtration treatment, recovery Ethanol Treatment by described successively containing alcohol mastic, obtain dealcoholysis mastic, wherein, the chilling treatment time is 30 ~ 40 hours;

5th step, adds cane sugar powder, active carbon by described dealcoholysis mastic, carries out heat treated, filtration treatment, dilution process successively, obtain semi-finished product; The weight ratio of described dealcoholysis mastic and described cane sugar powder is 1: 0.1 ~ 0.3; The weight ratio of described dealcoholysis mastic and described active carbon is 1: 0.001 ~ 0.002; The time of described heat treated is 30 ~ 40 minutes, and temperature is 100 DEG C ~ 110 DEG C;

6th step, the more described semi-finished product that the 5th step obtains are carried out filtration treatment, embedding process, sterilization treatment successively, obtain described drug oral liquor.

The dosage form of medicine can be: sugar coated tablet, film coated tablet, enteric coated tablet, hard capsule, soft capsule, oral liquid, suck agent, granule, electuary, honey pill agent, powder, sublimed preparation, solution, injection, suppository, plaster, syrup, powder, liniment, enema and patch.

The invention has the beneficial effects as follows: Chinese medicine of the present invention has the kidney invigorating and essence nourishing, effect of nourishing blood for regulating menstruation, cure mainly hypomenorrhea nephrasthenia syndrome.The present invention utilizes Traditional Chinese medical theory, payes attention to the combination at Overall View and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, is improving animal economy functional condition, improve overall immunity, regulate QI and blood, while improving plasma metabolism, for different clinical symptoms, selectivity medication, targeting is stronger, drug effect is gone directly focus, short treating period, and untoward reaction is few, not easily produce drug resistance, safely, effectively, cost price is low, route of administration is convenient, and patient is easy to accept.

Detailed description of the invention

Hypomenorrhea, returns at " menoxenia " category in the doctor's work before gold dollar.It is cold coagulation that Plain Questions of Huangdi's Internal Classic head carries its pathogenesis, and by later age, doctor is followed.Chinese Zhang Zhongjing " Medical Treasures of the Golden Chamber " is called " menstrual disorders "; Sui. Chao Yuanfang (550-630 A.D.) " General Treatise on the Cause and Symptoms of Diseases " row " unsmooth menorrhea time "; From golden Liu Wansu, hypomenorrhea is begun there is independent discussion.Through continuous investigation and the discussion of ancient Chinese medicine doctor, gradually perfect to the understanding of primary disease.Sick position highlights spleen kidney, born of the same parents are dirty, punching is appointed, highlight cold coagulation in pathogenesis, heat is burnt, blood deficiency, blood stasis, phlegm-damp, treatment upper with deficiency syndrome should be treated by tonifying method, puckery then lead to for rule for the treatment of, have blood-supplementing blood-nourishing, clearing away heat and cooling blood, warming the meridian and activating blood circulation accordingly, a different method for the treatment of such as to invigorate blood circulation of eliminating the phlegm.Put into practice by diagnosis and treatment, have accumulated many effective treatment sides medicine, for research today and treatment hypomenorrhea provide example.

Therefore, treatment hypomenorrhea nephrasthenia syndrome, the present invention is with the kidney invigorating and essence nourishing, nourishing blood for regulating menstruation is primary treatment principle, selects prescription: Placenta Hominis, the Cortex Eucommiae, Semen Astragali Complanati, Gecko, Cornu Cervi Pantotrichum, Hippocampus, Testis et penis callorhini, Radix Rehmanniae Preparata, Arillus Longan, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati, Fructus Lycii, Fructus Ligustri Lucidi, Carapax Et Plastrum Testudinis, Flos Rosae Rugosae, Herba Aristolochiae, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Caulis Spatholobi, Testis Caprae seu Ovis, Aeschna melanictera, Carnis Elaphuri davidiani, Fructus rubi tephrodis, Air Bladder pseudosciaenae seu Acipenser, Spongilla, Semen glycines sojae, Caulis Cucurbitae, rose hip, Radix Phyllagathis fordii.

Wherein, Placenta Hominis, the Cortex Eucommiae, Semen Astragali Complanati, Gecko, Cornu Cervi Pantotrichum, Hippocampus, Testis et penis callorhini, Testis Caprae seu Ovis, Aeschna melanictera, Carnis Elaphuri davidiani, Fructus rubi tephrodis, Air Bladder pseudosciaenae seu Acipenser, Spongilla, Semen glycines sojae, Caulis Cucurbitae support kidney benefit essence; Radix Rehmanniae Preparata, Arillus Longan, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati, Fructus Lycii, Fructus Ligustri Lucidi, Carapax Et Plastrum Testudinis, rose hip, Radix Phyllagathis fordii nourishing kidney, enrich and benefit essence and blood; Flos Rosae Rugosae, Herba Aristolochiae replenishing QI to invigorate the spleen, regulating QI to relieve pain; Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Caulis Spatholobi promoting blood flow to regulate menstruation.Full side's compatibility is rigorous, QI invigorating, spleen invigorating, supports kidney, regulating menstruation, benefiting essence-blood.

Now each taste medicine is described below:

Placenta Hominis: sweet, salty, warm; Enter lung, the heart, kidney channel.Supplement to the Herbal: " main QI and blood weakness and emaciation, married woman strains, and it is black that skin is blackened in face, all diseases gradually thin worried person in abdomen." modern medicine study thinks, Placenta Hominis is containing protein, sugar, calcium, vitamin, immune factor, estrogen, gravidity assisting ketone, steroid hormone, promoting sexual gland hormone, thyroliberin etc., mammary gland can be promoted, uterus, vagina, the growth of testis, also facilitation is had to thyroid, clinically be used for the treatment of uterine hypoplasia, metratrophia, myometritis, functional menolipsis, metrorrhagia, milk deficiency etc., all there is significant curative effect, to pulmonary tuberculosis, bronchial asthma, anemias etc. also have good effect, grind oral or coloclysis into powder and can prevent measles or mitigation symptoms.Also certain curative effect is had to portal cirrhotic ascites and schistosomicide end-age cirrhosis ascites.

The Cortex Eucommiae: sweet in the mouth, micro-pungent, warm in nature, enters liver, kidney channel." beautiful Chinese catalpa medicine solution ": " liver and kidney tonifying, nourishing muscle and tendon bone go to joint to wet excessive.Control soreness of waist and knee joint, the contracture of lower limb foot." Shennong's Herbal: " main pain along the spinal column, invigorating middle warmer benefit vital essence, hard muscles and bones, Qiang Zhi, except wet, dribbling urination of itching under the moon." " property of medicine opinion ": " control the cold buttocks lumbago of kidney, waist disease people is empty and stiffness of the body is straight, and wind is also.Waist unfavorable adding and use it." Cortex Eucommiae has invigorating the liver and kidney, bone and muscle strengthening, rubbish in purged body; strengthen human body cell substance metabolism; prevent muscle skeleton aging, balanced human's blood pressure, decomposer inner cholesterol; reduce body fat; recover blood vessel elasticity, diuresis heat clearing away, broad-spectrum antiseptic; stimulating central nervous system, improve leukocyte pharmacological action.The leaf of the Cortex Eucommiae and skin contain the nutritional labelings such as protein, fat, vitamin and mineral.Cortex Eucommiae free amino acid is few, a small amount of protein contained, be with most foodstuff like adequate proteins, namely can be hydrolyzed 8 seed amino acids detected needed by human.The Cortex Eucommiae has regulating action in various degree to immune system, hormonal system, central nervous system, blood circulation and urinary system, the excited Pituitary Adrenalcortical system of Cortex Eucommiae energy, adrenal cortex reinforcing function.Zoopery shows, the Cortex Eucommiae contain a kind of promote human body skin, skeleton, protein collagen in muscle the special composition of composition and decomposition, have and promote metabolism, prevent the function that fails.

Semen Astragali Complanati: warm in nature, sweet in the mouth, " Bencao Congxin ": " the kidney invigorating, reinforcing YIN-essence, benefit essence, improving eyesight.Control leukorrhagia, anal fistula, cloudy Huang, performance controlling nocturnal emission with astringent drugs." " book on Chinese herbal medicine asks former ": " control consumptive lung disease, kidney is cold, frequent micturition, incontinence of urine, improving eyesight, longue meat." there is temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination, the effect of improving eyesight, for impotence due to deficiency of the kidney, seminal emission premature ejaculation, frequent micturition, or leukorrhagia, soreness of the waist and knees, lumbago; Deficiency of the liver and kindey, blurred vision order is dark, the cards such as visual deterioration.

Gecko: salty, flat.Return lung, kidney channel.Invigorating the lung and the kidney, helping inspiration to relieve asthma, supporing yang benefit essence.For cough due to deficiency of the lung, suffer from a deficiency of the kidney and breathe heavily, asthenia is breathed with cough.This product double enter lung kidney two warp, being longer than tonifying the lung gas, helping kidney yang, Dingchuan coughs, is the good merchantable brand that Zhiduo County plants deficiency syndrome and breathes with cough.

Cornu Cervi Pantotrichum: sweet, salty, temperature.Return kidney, Liver Channel.Invigorating kidney-YANG, mends marrow, bone and muscle strengthening, adjusts punching to appoint, holder sore.Cure mainly diseases such as suffering from a deficiency of the kidney, dizzy, deaf, order is dark, sexual impotence, spermatorrhea, cold womb are infertile, weakness and emaciation, Mental fatigue, fear of cold, spinal column cold type of pain, muscles and bones flaccidity are soft, bleeding not during menses, carbuncle of yin nature are not held back and prolonged illness is deficient.Cornu Cervi Pantotrichum contains aminoacid, lecithin, vitamin and the trace element etc. abundanter than Radix Ginseng.Cornu Cervi Pantotrichum is warm in nature and not dry, has and rouses oneself and improve body function, to patient after asthenia universalis, prolonged illness, have good health-care effect.Cornu Cervi Pantotrichum can improve cellular immunization and the humoral immune function of body, promotes lymphocytic conversion, has the effect of immunopotentiating agent.It can increase body defence capability to external world, the immunologic balance in control agent and avoid disease to occur and promote wound healing, sick body rehabilitation, thus plays strengthening body, to antidotal effect.

Hippocampus: Gan Wen.There is effect of kidney invigorating and YANG supporting, warm promoting blood circulation, tranquillizing and allaying excitement, mass dissipating and swelling eliminating, relaxing muscles and tendons and activating QI and blood in the collateral, relieving cough and asthma.Hippocampus is warm in nature supporing yang, can promoting the flow of QI-blood by warming the meridian, effect of invigorating blood circulation again, cure mainly suffer from a deficiency of the kidney, sexual impotence, the enuresis.Hippocampus is the rare Chinese medicine that a kind of economic worth is higher, has the medicinal functions such as building body, kidney invigorating and YANG supporting, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic, tranquillizing and allaying excitement, relieving cough and asthma, particularly more effective for the neural disease for the treatment of.Hippocampus, except mainly for the manufacture of except various synthetic drug, can also directly take to be healthy and strong and cure the disease.Hippocampus can strengthen mice anoxia enduring, reduces the activity of monoamine oxidase, MAO, reduces lipid peroxidation body content in vivo.In addition, various Hippocampus extract all has the effect of calcium channel blocker.By blocking Ca2+ influx, reach effect of neuroprotective unit.

Testis et penis callorhini: salty in the mouth, hot in nature, returns liver.Warming the kidney tonifying YANG, benefit essence mends marrow.Control deficient impairment caused by overstrain, sexual impotence essence declines, premature ejaculation, waist knee flaccidity, trusted subordinate's pain.One, tonifying YANG YIN nourishing, kidney-supplementing liver-boosting, endocrine regulation.Its whip is put down, and enters liver the kidney invigorating.Be applicable to because of diseases such as sexual impotence, premature ejaculation, sexual disorder and the insomnia and dreamful sleep caused by the groan kidney deficiency such as damage of kidney-YIN, insufficiency of kidney-YANG, dizzy forgetful, soreness of waist and knee, neurasthenia and immunologic hypofunctions; Two, blood yiqi.Hemoglobin in Testis et penis callorhini and hemoglobin high, be applicable to blood deficiency gas weak person; Three, skin care skin Caring.Containing a large amount of viscous protein in Testis et penis callorhini, there is slow down aging, keep the function of elasticity of skin and moisture; Four, bone and muscle strengthening.Testis et penis callorhini is the kidney invigorating treasure, and kidney by force then can bone and muscle strengthening.

Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature, enters liver, kidney channel, Compendium of Material Medica: " fill out bone marrow, longue meat, promoting generation of vital essence and blood.Tonifying five ZANG-organs internal injury is not enough, and promoting blood circulation, sharp knowledge, black beard and hair, man's five kinds of strain and seven kinds of impairment, woman's damaging the spleen and stomach threatened abortion, irregular menorrhea, tire produces all kinds of diseases and ailments." there is YIN nourishing of enriching blood, beneficial essence fills out the effect of marrow, for blood deficiency and yellow complexion; Dizzy, cardiopalmus, insomnia, menoxenia, collapses more than; Hepatic and renal YIN deficiency, night sweat, sufficient knee joint pain, soreness of the waist and knees, Hiccough and deaf, the head is dim-sighted, and seminal emission sexual impotence, infertility, menoxenia, metrostaxis, early whitening of beard and hair, quenches one's thirst, the cards such as dyspnea with rapid and short breath of suffering from a deficiency of the kidney.

Arillus Longan: " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " nourishing blood to tranquillize the mind, long intelligence arresting sweating, appetizing strengthening the spleen." " Quanzhou book on Chinese herbal medicine ": " tonifying YANG QI invigorating, tonifying the spleen and stomach.Control married woman's puerperal edema, deficiency of vital energy edema, diarrhea due to hypofunction of the spleen.Invigorating the heart and spleen, " nourishing blood to tranquillize the mind.For insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion.Contained by Arillus Longan, sugar amount is very high, is the monosaccharide of absorption easy to digest, can be directly absorbed by the body, thus weak anemia, worn with age, weakness due to chronic disease, often eating a little Arillus Longan is have benefiting action very much; Women puerperal, Arillus Longan is also that food mended in important tune.Because iron content and vitamin B2 are very abundant, uterine contraction and the sagging sense of palace body can be alleviated., anemia weak for women puerperal, body void etc., then available Arillus Longan adds Radix Angelicae Sinensis, Fructus Lycii, Fructus Jujubae (enucleation) several stewed chickens.Or every day eats Arillus Longan boiled egg, can promoting blood flow to regulate menstruation, promote antisecosis.

Radix Asparagi: cold in nature, sweet and slightly bitter taste; Enter liver, lung, kidney channel." property of medicine opinion ": " main lung qi cough with dyspnea, pant short anxious, heat extraction, leads to kidney qi, treats the raw carbuncle vomiting pus of consumptive lung disease, controls scabies humida, only quench one's thirst, apoplexy of reducing phlegm and internal heat, should take for a long time." " Japan hanako materia medica ": " beneficial skin, improving healthy complexion, mends five kinds of strain and seven kinds of impairment, controls lung qi and cough, expectorant, migratory arthralgia pyretic toxicity, urticaria, unhappy haematemesis for relieving palpitation, moistening five ZANG-organs." to general benign breast tumor, especially breast lobule hyperplasia, no matter Tumor size, prove effective rapidly, great majority can obtain healing.Have and calm the nerves, nourish heart, lung moistening, tonification, nourishing kidney, the curative effect such as blood pressure lowering and loosening bowel to relieve constipation.Decoct in vitro tests all has bacteriostasis in various degree to anthrax bacillus, A type and beta hemolytic streptococcus, diphtheria corynebacterium, diphtheroid, Diplococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, Staphylococcus albus and bacillus subtilis.

Herba Dendrobii: cold nature, sweet in the mouth, returns stomach, kidney channel, has reinforcing stomach reg fluid, effect of nourishing YIN and clearing away heat.Cure mainly cloudy impairment of body fluid to lose, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, the cards such as poor vision.Herba Dendrobii can significantly improve superoxides discrimination China enzyme (SOD) level, reduces lipid peroxide (LPO), regulates brain monoaminergic transmitters level, suppresses similar monoamine oxidase, MAO (MAO), play the effect of slow down aging.Herba Dendrobii contains lactone component, has the condensation of blood circulation promoting and blood stasis dispelling, blood vessel dilating and antiplatelet, and treatment embolic occlusion pulse tube is scorching, cerebral thrombosis, the effects such as arteriosclerotic obliteration.The luxuriant and rich with fragrance class extracted in Herba Dendrobii and bibenzyl material, have the effect of anti-pulmonary carcinoma, adenocarcinoma ovaries and promyelocitic leukemia.Herba Dendrobii has excitation to intestinal tube, and shrinkage amplitude can be made to increase.Pharmacological testing shows, oral Herba Dendrobii decoct can promote gastric secretion, helps digest.

Rhizoma Polygonati: sweet in the mouth, property is put down, and enters lung, spleen, kidney channel, there is enriching qi and yin, spleen invigorating lung moistening, effect of enriching kidney essence, for taste deficiency of qi and yin, lack of appetite is unable, lung-dryness syndrome due to deficiency of YIN, the few expectorant of dry cough, dry cough expectorant is few, polydipsia of quenching one's thirst, weakness of the spleen and stomach, deficiency of spleen-QI or deficiency of spleen-YIN, quenching one's thirst of yin asthenia generating intrinsic heat, the card such as deficiency of kidney essence, impotence and seminal emission, dizziness and tinnitus, blurred vision dim eyesight.

Fructus Lycii: sweet is flat.Enter liver, kidney, lung meridian." Treatise on Dietetic Therapy ": " hard muscle is always resistance to, and except wind, tonification muscles and bones, the beneficial people of energy, removes asthenia." control hepatic and renal YIN deficiency, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, impotence and seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.The effects such as lycium barbarum polysaccharide has Promote immunity, defying age, antitumor, scavenging free radicals, resisting fatigue, radioprotective, protects the liver, reproductive function protection and improvement.Carotene is the main active of wolfberry pigment, has antioxidation and as the important physiological function of the synthesis precursor etc. of vitamin A.Mouse gavaging Fructus Lycii water extract or intramuscular injection alcohol extract and lycium barbarum polysaccharide, the phagocytic function of the macrophage that is improved, strengthens the effect of serum lysozyme, improves tiring of anti-sheep red blood cell (SRBC) antibody in serum.Wolfberry fruit extract significantly and lastingly can reduce rat blood sugar, increase carbohydrate tolerance, and toxicity is less.

Fructus Ligustri Lucidi: sweet in the mouth, hardship, be slightly cold, enters liver, kidney channel, has strong liver kidney tonifying, the effect of clearing away heat to improve acuity of vision, is mainly used in treating hepatic and renal YIN deficiency, and the head loses foster dizzy tinnitus, the symptoms such as yin asthenia generating intrinsic heat.This product energy tonifying liver kidney yin, but the efficacy of a drug is gentle, slowly must get effect.Compendium of Material Medica is recorded: " to insult winter verdant for this wood, has the behaviour that chastity is kept, therefore with Fructus Ligustri Lucidi shape it ... to put wax insect time near, therefore be commonly called as wax tree." Fructus Ligustri Lucidi can promote leukocyte, strengthens effect of immunologic function, has stronger inhibitory action to staphylococcus aureus, dysentery bacterium.Modern medicine study proves, Fructus Ligustri Lucidi includes ursolic acid, mannitol, glucose, fatty wet goods, has heart tonifying, diuresis and hepatoprotective effect, the leukopenia quantity caused because of chemotherapy can be made to raise, and have inhibitory action to staphylococcus aureus, escherichia coli.

Carapax Et Plastrum Testudinis: salty, sweet, is slightly cold; Return liver, kidney, heart channel.Compendium of Material Medica: " reinforcing the heart, the kidney invigorating, to enrich blood, all with yin nourishing also ... see Carapax Et Plastrum Testudinis and lead all diseases, all genus deficiency of YIN blood is weak." nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, reinforcing the heart of nourishing blood.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, has a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and muscles and bones flaccidity is soft, has a guilty conscience forgetful.Certain contraction is had to Isolated Rat Uterus during decoct high concentration; Inhibitory action is had to Bacillus tuberculosis; The continuous gavage of Carapax Et Plastrum Testudinis decoct has impact to rat hormonal system in 6 days.Carapax Et Plastrum Testudinis can improve animal " deficiency of YIN " and demonstrate,prove pathology animal functional status, makes it to recover normal; Immunologic function can be strengthened; There is the effect of two-ways regulation DNA synthetic ratio; All excitation is had in vitro and Uterus in vivo; Have antipyretic, enrich blood, sedation; Still there is anticoagulation, increase coronary flow and improve the effects such as hypoxia-bearing capability; Colla Plastri Testudinis has certain effect promoting leukocyte count.

Flos Rosae Rugosae: warm in nature, sweet and slightly bitter taste, returns liver spleen channel.Supplementary Amplifications of the Compendium of Materia Medica: " and blood, promoting the circulation of blood, regulates the flow of vital energy.Control migratory arthralgia." " book on Chinese herbal medicine is new again ": " the strongly fragrant gas of soothing liver-QI gallbladder, spleen invigorating pathogenic fire reducing.Control cold type of pain in abdomen, gastral cavilty is long-pending cold, and holding concurrently can removing blood stasis." promoting the circulation of QI, promoting the circulation of blood, control migratory arthralgia, loose tired pain relieving.Flos Rosae Rugosae and Herb have convergence, can be used for woman in menstrual period too much, and leucorrhea with red and white discharge and enteritis, dysentery, the red half of intestinal are hemorrhage.To regulate the flow of vital energy resolving depression and blood dissipating blood stasis.Cure mainly stomachache due to hyperactive liver-QI attacking the stomach, new lingering pathogenic wind numbness, spitting of blood of spitting blood, menoxenia, leucorrhea with red and white discharge, dysentery, acute mastitis, toxic swelling.Containing 300 various chemical components in Flos Rosae Rugosae, as the alcohol of fragrance, aldehyde, fatty acid, phenol and containing the oil of essence and fat, to wake up stomach with easing the affected liver in normal food Flos Rosae Rugosae goods, have a respite and invigorate blood circulation, looks improving and the skin nourishing, make us refreshing refreshing.

Herba Aristolochiae: bitter, temperature; Enter liver,spleen,kidney warp." Bencao Tujing ": " Xie Fenglao.Herba Ephedrae then cures the wound cold diaphoresis, with Radix Et Rhizoma Rhei with taking gas." " book on Chinese herbal medicine is new again ": " removing heat from blood and promoting blood circulation, removes wind dampness removing, walks meridians, doublely controls the swollen pain of waist lower limb." circulation of qi promoting removing dampness, promoting blood circulation and stopping pain.Treat for stomachache, colicky, edema during pregnancy, puerperal, vim and vigour were suffered from abdominal pain, rheumatalgia.Promoting flow of QI and blood, pain relieving, diuresis.Edema during pregnancy, breast is suffered from abdominal pain, colic, rheumatalgia.Herba Aristolochiae, gas is invigorated blood circulation, and controls the medicine of all pains also.The gas of the person, suitable then peaceful, the inverse then vexed work of pain.As Young " side of directing at " Herba Aristolochiae controls the brachialgia of expectorant note, gas stays colic, and abdominal mass is gathered, and renal mass is suffered from abdominal pain, and puerperal, vim and vigour were suffered from abdominal pain, and he is as edema during pregnancy, edema over the face tachypnea, man's wind labor, and chronic cough is not healed, and knows and controls it with this medicine, peace of invariably getting into bed.Gai Weiqi is good at popular vim and vigour therefore also.See book discuss and cure mainly, only belong to the diseases such as pregnant edema during pregnancy, stomachache, wind consumptive disease, in his disease then not and here.Its reason controlled i.e., also only because bitter in the mouth master is in catharsis, warm in nature being led to lives, therefore passage of invigorating blood circulation, and makes water without unfavorable, and wind removes invariably, blood work invariably, and pain to be controlled therefore also all invariably with swollen.

Radix Salviae Miltiorrhizae: bitter in the mouth, cold in nature, enters the heart, Liver Channel, has the effect of blood circulation promoting and blood stasis dispelling, promoting tissue regeneration by removing blood stasis, removing heat from blood mind calming, be mainly used in the ambition of stagnation of QI and blood, the twinge of the breast side of body, sensation of oppression over the chest with shortness of breath, abdominal distention; The menoxenia of women's disharmony between QI and blood, dysmenorrhoea amenorrhea; Stagnation of QI-blood, the symptoms such as trusted subordinate's pain, Radix Salviae Miltiorrhizae can reduce as interior fat and testis peripheral adipose, alleviates insulin secretion and glycometabolic Random early Detection.Strengthen myocardial contraction, improve cardiac function, do not increase myocardial oxygen consumption.Coronary artery dilating, increases myocardial flow; Expansion peripheral blood vessel, blood flow increases; Cerebral blood flow declines, and improves plasmin activity; Extend bleeding and cotting time; Anticoagulant (improve cAMP level in platelet and suppress TXA2 synthesis); Improve hemorheological properties (blood viscosity reduction, erythrocyte electrophoretic time are shortened).

Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is put down; Return liver, kidney channel." Japan hanako materia medica ": " control waist knee joint soft timid cold weak, broken crux, evacuation of pus pain relieving, puerperal cardiac and abdominal pain blood fortune, fall tire, tonifying YANG." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " control furuncle, carbuncle, apply affected part.Also can have an abortion.Food is simmered, energy improving eyesight with Carnis Sus domestica." there is invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, ignite (blood) is descending, effect of inducing diuresis for treating stranguria syndrome, the inclined nourishing the liver and kidney of Radix Achyranthis Bidentatae merit, strong waist knee joint: the soreness of bones and muscles, the lumbocrural pain that cause for deficiency of the liver and kindey.Radix Cyathulae is with promoting blood circulation to restore menstrual flow, and wind-damp dispelling is good at: for blood stasis amenorrhea and rheumatalgia.This moral character is apt to descending, and fire and the top of specially controlling inflammation are hemorrhage, therefore is usually used in the disease such as conjunctival congestion, pharyngeal swelling, haematemesis, epistaxis of hyperactivity of deficient fire or heat in blood upper punch.The traditional Chinese medical science is thought, its property bitter but sweet flavor acid is flat, has promoting blood circulation to restore menstrual flow, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, draws effect that blood (fire) is descending, be usually used in the gynaecopathia such as amenorrhea, dysmenorrhea, menoxenia, puerperal abdonimal pain for the treatment of stagnation of blood stasis, traumatic injury, the soreness of waist and knee joint of suffering from a deficiency of the kidney, weakness of the lower extremities, hematuria; dysuria, the cards such as the headache that Urethra astringent pain and burning hot upper inflammation cause, dizzy, haematemesis, epistaxis.

Caulis Spatholobi: nature and flavor are bitter, sweet, temperature.Return liver, kidney channel.Can relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation.Main numb hand and foot; Quadriplegia; Rheumatic arthralgia; Women has through uncomfortable; Dysmenorrhea; Amenorrhea.Function: enrich blood, invigorates blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.This product is containing formoononetin, ononin, prunusetin., A Fuluomoxin, cajinin, licochalcone, isoliquiritigenin, tetrahydroxy chalcone derivative, Daidezin, 7-hydroxy-11,12-(methylenedioxy)coumestan, 9-O-methoxyl group coumestrol, 3,7-dihydroxy-6-melonia flavonol, epicatechin, protocatechuic acid, freidelin-3b-alcohol, b-sitosterol, daucosterol and 7-ketone group-b-sitosterol.Pharmacological action: to the effect of hemopoietic system; To the effect of blood coagulation, fibrinolytic; Suppress heart and the effect of reducing blood pressure; Antitumaous effect; To the adjustment of lipid metabolism.

Testis Caprae seu Ovis: nature and flavor are sweet; Salty; Warm in nature.Return through kidney channel.Function cures mainly the kidney invigorating; Benefit essence; Supporing yang.Main deficiency of kidney essence; Lumbar and back pain; Sexual impotence is sombre; Seminal emission; Spermatorrhea; Stranguria with turbid discharge; Leukorrhagia; Quench one's thirst; Frequent micturition; Hernia; Painful and swollen testis.

Aeschna melanictera: all there is distribution national the greater part.Concoct " Japan hanako materia medica ": " be used as medicine wing foot, fries with good." nature and flavor 1. " not Lu ": " be slightly cold." 2. " Japan hanako materia medica ": " is cool, nontoxic." function cures mainly kidney tonifying reinforcing YIN-essence.Control emission due to deficiency of the kidney, sexual impotence.1. " not Lu ": " reinforcing YIN-essence is essence only." 2. " Japan hanako materia medica ": " tonifying YANG, warming the kidney." 3. " conventional glossary of Herbs and Drugs among the people ": " endogenous wind stopping is relieving convulsion." 4. " Luchuan book on Chinese herbal medicine ": " controls impotence of suffering from a deficiency of the kidney."

Carnis Elaphuri davidiani: nature and flavor are sweet; Warm in nature.Return through spleen; Kidney channel.Function cures mainly invigorating middle warmer gas; Kidney tonifying essence; Bone and muscle strengthening; Blood circulation regulating.Main asthenia is not enough; Waist foot is weak; Puerperal exposure to wind is empty.

Fructus rubi tephrodis: the sweet acid of nature and flavor, temperature.1. " herbal classic ": " acid, flat." 2. " not Lu ": " be salty, nontoxic." 3. " feeding habits book on Chinese herbal medicine ": " sweet acid, slight fever." function cures mainly invigorating the liver and kidney, urine reducing.Zhiduo County urinates, the vertigo.1. " herbal classic ": " long cloudy order is hard, and strong will times power, has son for main settling five organs, beneficial vital essence." 2. " not Lu ": " treats sudden and violent apoplexy, and fever of the body is frightened." 3. Tang Materia Medica:, " resistance to cold-damp, good color." 4. " daily book on Chinese herbal medicine ": " urine reducing, black and white is sent out." 5. " medical center bun is wanted ": " tonifying the lung, cold removing."

Air Bladder pseudosciaenae seu Acipenser: nature and flavor are sweet is flat.1. " Haiyao Bencao, Oversea Materia Medica ": " nontoxic." 2. " detailed outline ": " is sweet, flat, nontoxic." " bladder glue, Gan Xian is flat, nontoxic." 3. " book on Chinese herbal medicine is newly organized ": " sweet in the mouth, temperature." returning through " book on Chinese herbal medicine is newly organized ": " enters kidney." function cures mainly the kidney invigorating and essence nourishing, nourishes muscle arteries and veins, hemostasis, dissipating blood stasis, detumescence.Control spermatorrhea of suffering from a deficiency of the kidney, puerperal puerperal tetanus, tetanus, spit blood, metrorrhagia, wound hemorrhage, hemorrhoid.1. supplement to the Herbal: " incarnation is prolonged does not go out person for main bamboo wood, and get four limits in white deposited skin ulcer, namely meat is rotten goes out thorn." 2. " Haiyao Bencao, Oversea Materia Medica ": " main eczema of the ear, the erosion of vulva, hemorrhoid, and ashing is used." 3. principle of Correct Diet: " and alcoholizing take it, and disappear tetanus." 4. " detailed outline ": " fish glue, only injured blood goes out incessantly; Bladder glue, charred medicinal herb with its property retained, control married woman difficult labour, puerperal tetany caused by wind pathogen, tetanus convulsion, preventing or arresting vomiting blood, dissipating blood stasis blood, detumescence poison." 5. " book on Chinese herbal medicine is newly organized ": " mends lean blood." 6. " book on Chinese herbal medicine asks former ": " nourishing muscle and tendon arteries and veins, determines hands war, controlling nocturnal emission with astringent drugs."

Spongilla: nature and flavor " detailed outline ": " sweet, temperature, nontoxic." function cures mainly Yiyang arresting seminal emission.Control sexual impotence, seminal emission, nebulousurine, leukorrhagia, incontinence of urine, eczema scrotum.1. " Elementary Medicine ": " main sun declines impotence." 2. " detailed outline ": " secret essence in Yiyang, treats true strength void exhausted, impotence, seminal emission, the heeltap, and nebulousurine is as fat, and incontinence of urine, pruritus due to damp pathogen under capsule, woman's YIN-cold cold belt, enters ball and fall apart and sit soup use."

Semen glycines sojae: nature and flavor are sweet is cool.1. " book on Chinese herbal medicine converges and says ": " sweet-bitter flavor is salty, and gas is trembled with fear, nontoxic." 2. " book on Chinese herbal medicine is through separating ": " gas is put down, and sweet in the mouth is nontoxic." 3. " Chinese herbal medicine is commonly used in Shanghai ": " is sweet, is slightly cold." return through 1. " herbal classic is met former ": " enters kidney channel blood system." 2. " book on Chinese herbal medicine is through separating ": " enters lung meridian, spleen meridian." function cures mainly liver and kidney tonifying, removing toxic substances of dispeling the wind.Control and cloudy lose blurred vision, lumbago due to renal deficiency, night sweat, bones and muscles pain, puerperal puerperal tetanus, infant malnutrition.1. " book on Chinese herbal medicine converges and says ": " separate interior-heat to quench one's thirst, only night sweat due to yin deficiency." 2. essentials of Matea Medica: " per morning, saline gulped down or saline is cooked, the kidney invigorating." 3. " book on Chinese herbal medicine is through separating ": " is raw grinds painting carbuncle." 4. " Shen Shi efficacious prescriptions ": " suppressing the hyperactive liver fire.Control infantile malnutrition, order disease." 5. " BAICAO mirror ": " white subcutaneous ulcer of harnessing the Yellow River." 6. " thing parent states and sees ": " tonifying five ZANG-organs, in benefit, helps the twelve regular channels, in tune, and warm the intestines and stomach, relaxing muscles and tendons." 7. " detailed outline is picked up any lost article from the road ": " strengthening bone and muscle, only night sweat, invigorating kidney, promoting blood circulation, improving eyesight benefit essence.Liquor takes, and separates crow, attached poison." 8. " book on Chinese herbal medicine is new again ": " spleen invigorating is except wind, inducing diuresis and reducing edema." 9. " decoction pieces is newly joined ": " supports lung suppressing the hyperactive liver, refresh oneself." 10. " Chinese herbal medicine is commonly used in Shanghai ": " suppressing the hyperactive liver, improving eyesight, has again strong effect.Control dizzy order flower."

Caulis Cucurbitae: nature and flavor " book on Chinese herbal medicine is new again ": " sweet-bitter flavor, cold nature is nontoxic." returning through " book on Chinese herbal medicine is new again ": " enters liver, spleen two warp." function cures mainly lung heat clearing, stomach function regulating, dredging collateral.Control pulmonary tuberculosis low grade fever, stomachache, menoxenia, scald.1. " book on Chinese herbal medicine is new again ": " suppressing the hyperactive liver and easing the stomach, the meridian dredging, sharp blood vessels, kidney nourishing water.Treating the liver wind, and blood nourishes blood, regulating menstruation is regulated the flow of vital energy, and doublely removes all wind." 2. " Chinese herbal medicine is commonly used in Shanghai ": " heat clearing away.Control pulmonary tuberculosis low grade fever."

Rose hip: nature and flavor acid; Bitter; Temperature.Return through liver; Spleen; Stomach; Urinary bladder channel.Function cures mainly strengthening the spleen to promote digestion; Promoting blood flow to regulate menstruation; Astringing lung-QI and relieving cough.Main dyspepsia; Inappetence; Abdominal distention; Diarrhoea; Menoxenia; Dysmenorrhea; Atherosclerosis; The cough of lung knot.

Radix Phyllagathis fordii: property mildly bitter flavor; Sweet; Cool in nature.Gui Jing returns liver; The heart; Urinary bladder channel.Function cures mainly nourishing blood for regulating menstruation.Main blood deficiency and yellow complexion; Menoxenia; Amenorrhea; Dysmenorrhea; Leukorrhagia.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Embodiment 1 capsule

Placenta Hominis 13g, Cortex Eucommiae 14g, Semen Astragali Complanati 15g, Gecko 10g, Cornu Cervi Pantotrichum 26g, Hippocampus 10g, Testis et penis callorhini 10g, Radix Rehmanniae Preparata 24g, Arillus Longan 27g, Radix Asparagi 12g, Herba Dendrobii 25g, Rhizoma Polygonati 12g, Fructus Lycii 14g, Fructus Ligustri Lucidi 26g, Carapax Et Plastrum Testudinis 18g, Flos Rosae Rugosae 15g, Herba Aristolochiae 27g, Radix Salviae Miltiorrhizae 12g, Radix Achyranthis Bidentatae 13g, Caulis Spatholobi 12g, Testis Caprae seu Ovis 13g, Aeschna melanictera 12g, Carnis Elaphuri davidiani 12g, Fructus rubi tephrodis 12g, Air Bladder pseudosciaenae seu Acipenser 12g, Spongilla 25g, Semen glycines sojae 14g, Caulis Cucurbitae 27g, rose hip 13g and Radix Phyllagathis fordii 14g.

Its preparation method is:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 4 times is the ethanol of 90%, reflux 4 hours, extracts, and filters acquisition first extracting solution; It is the ethanol of 90% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 times again, reflux 1 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 2 hours, pulverize, sieve, obtain 400 object micropowders;

3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15:0.5, incapsulate in housing, obtain capsule by described capsule 's content.

Embodiment 2 oral solutions

Placenta Hominis 23g, Cortex Eucommiae 20g, Semen Astragali Complanati 22g, Gecko 19g, Cornu Cervi Pantotrichum 20g, Hippocampus 18g, Testis et penis callorhini 20g, Radix Rehmanniae Preparata 20g, Arillus Longan 20g, Radix Asparagi 20g, Herba Dendrobii 20g, Rhizoma Polygonati 20g, Fructus Lycii 20g, Fructus Ligustri Lucidi 20g, Carapax Et Plastrum Testudinis 13g, Flos Rosae Rugosae 30g, Herba Aristolochiae 20g, Radix Salviae Miltiorrhizae 24g, Radix Achyranthis Bidentatae 24g, Caulis Spatholobi 20g, Testis Caprae seu Ovis 18g, Aeschna melanictera 18g, Carnis Elaphuri davidiani 20g, Fructus rubi tephrodis 18g, Air Bladder pseudosciaenae seu Acipenser 24g, Spongilla 20g, Semen glycines sojae 20g, Caulis Cucurbitae 20g, rose hip 23g and Radix Phyllagathis fordii 20g.

Its preparation method is:

The first step, mixes Placenta Hominis, the Cortex Eucommiae and Semen Astragali Complanati, add relative to mixture 2 times amount determining alcohol be 65% alcohol reflux 4 times, each 2 hours, filter, filtrate merges, and reclaim ethanol, being concentrated into 80 DEG C of relative densities is the mastic of 1.20, for subsequent use;

Second step, is mixed in proportion described for residue raw medicinal material, adds relative to mixture 2 times of water gagings, boils 2 hours, and filter, being concentrated into 80 DEG C of relative densities is the mastic of 1.22;

3rd step, the described mastic mixing that the first step, second step are obtained, 65 DEG C of reduced vacuum dryings, get dry extract powder;

4th step, is added ethanol in the described dried cream powder that the 3rd step is obtained, and obtains containing alcohol mastic, and the described alcohol content containing alcohol mastic is 65%; Carry out chilling treatment, precipitation process, filtration treatment, recovery Ethanol Treatment by described successively containing alcohol mastic, obtain dealcoholysis mastic, wherein, the chilling treatment time is 30 hours;

5th step, adds cane sugar powder, active carbon by described dealcoholysis mastic, carries out heat treated, filtration treatment, dilution process successively, obtain semi-finished product; The weight ratio of described dealcoholysis mastic and described cane sugar powder is 1: 0.3; The weight ratio of described dealcoholysis mastic and described active carbon is 1: 0.002; The time of described heat treated is 40 minutes, and temperature is 110 DEG C;

Embodiment 3 honey refining pill

Placenta Hominis 23 weight portion, the Cortex Eucommiae 20 weight portion, Semen Astragali Complanati 22 weight portion, Gecko 19 weight portion, Cornu Cervi Pantotrichum 26 weight portion, Hippocampus 18 weight portion, Testis et penis callorhini 20 weight portion, Radix Rehmanniae Preparata 24 weight portion, Arillus Longan 27 weight portion, Radix Asparagi 20 weight portion, Herba Dendrobii 25 weight portion, Rhizoma Polygonati 20 weight portion, Fructus Lycii 20 weight portion, Fructus Ligustri Lucidi 26 weight portion, Carapax Et Plastrum Testudinis 18 weight portion, Flos Rosae Rugosae 30 weight portion, Herba Aristolochiae 27 weight portion, Radix Salviae Miltiorrhizae 24 weight portion, Radix Achyranthis Bidentatae 24 weight portion, Caulis Spatholobi 20 weight portion, Testis Caprae seu Ovis 18 weight portion, Aeschna melanictera 18 weight portion, Carnis Elaphuri davidiani 20 weight portion, Fructus rubi tephrodis 18 weight portion, Air Bladder pseudosciaenae seu Acipenser 24 weight portion, Spongilla 25 weight portion, Semen glycines sojae 20 weight portion, Caulis Cucurbitae 27 weight portion, rose hip 23 weight portion and Radix Phyllagathis fordii 20 weight portion.

Its preparation method is:

Step 1: by grind into powder after Cornu Cervi Pantotrichum, Semen glycines sojae and Testis Caprae seu Ovis distillation crystallization;

Step 2: get 95% soak with ethanol 1.5 hours, heating extraction 2 times that surplus stock medical material adds 2 times amount again, each 1.0 hours, filter to obtain extracting solution, merge extractive liquid, be the ultrafiltration post ultrafiltration of 74000 again through the molecular weight that dams, ultrafiltration decompression removing ethanol, during simmer down to 80 DEG C, relative density is the extractum of 1.13, becomes component 1;

Step 3: the medicinal residues that step 2 obtains add 2 times amount water soaking 1.0 hours, extracts 1 time, is the extractum of 1.1, as component 2 by relative density during extracting solution heating under reduced pressure simmer down to 85 DEG C for 1.0 hours;

Step 4: component 1, component 2 are mixed with the powder that step 1 obtains, adds and is twisted into honey refining pill relative to the Mel of mixture 2 times amount.

The toxicity test of medicine

Acute toxicity test: select white mouse 20, is divided into test group 10 and matched group 10 at random, test group 10 only with the capsule of the embodiment of the present invention 1 for object, give white mouse large enteral dispensing, observe 7 for 150 times of clinical consumption per day.All white mouse of result test group are strong deposits, and its activity, diet, hair, Excreta are no abnormal, have no toxic reaction, with matched group indifference.Irritation test is carried out to the white mouse vagina of test group and damaged skin, there are no irritative response and other untoward reaction.Toxicity test proves, this medicine does not have toxic action and untoward reaction, and clinical practice is safe and reliable.

Long term toxicity test: select NH mice 30, be divided into test group 15 and matched group 15 at random, the oral liquid of the embodiment of the present invention 2 is carried out gavage to 15 of test group mices, by 7.5ml, 15ml and 45ml crude drug/kg continuous use 12 weeks (1.0ml/100g body weight, every day 2 times) and drug withdrawal after 4 weeks, result shows: medicine of the present invention is to the hair of test group mice, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, the indexs such as blood fat all have no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 12 weeks and drug withdrawal are after 4 weeks, Organs of Mice is all without obviously changing.Illustrate that medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.

Clinical trial

Case selection: during choosing in April ,-2012 in April, 2011, the patient of the hypomenorrhea of my institute's diagnosis and treatment is 320 examples, is renal deficiency type.Wherein, less than 20 years old patient populations 80 people, 20-35 year patient populations 100 people, more than 35 years old patient populations 140 people.320 routine patient's course of disease more than 3 months person 100 examples, half a year, above person 130 was routine, more than 1 year 90 example.This 320 routine patient carried out random packet, is divided into treatment one group, treats two groups, treat three groups and randomized controlled treatment group, often organize each 80 people, test.

Diagnostic criteria:

1. menstrual cycle is normal, through measuring seldom, less than 30ml, even drop is namely clean.

2. primary disease should be differentiated mutually with early pregnancy menstruating on time after pregnancy.

3. get rid of the hypomenorrhea because tuberculosis causes.

4. few through carrying out amount, namely clean within the next few days, or namely drop stops, and color is light dim, and matter is rare, waist soreness, dizziness and tinnitus, frequent micturition, light red tongue, thin fur, deep-thready pulse.

Therapeutic Method:

Treat one group: this organizes 80 people, adopt the capsule agent of the embodiment of the present invention 1 to treat.In menstrual cycle the 5th day, each 1, every day twice, be used in conjunction 5 days courses for the treatment of.Treat that next menstrual cycle 5 days is a course for the treatment of again.Continue to carry out three courses for the treatment of.Observe latter 6 months for the treatment of.And follow up a case by regular visits to observation half a year with or without recurrence.

Treat two groups: this organizes 80 people, adopt the oral solutions of the embodiment of the present invention 2 to treat.In menstrual cycle the 5th day, each 15ml, every day twice, was used in conjunction 5 days courses for the treatment of.Treat that next menstrual cycle 5 days is a course for the treatment of again.Continue to carry out three courses for the treatment of.Observe latter 6 months for the treatment of.And follow up a case by regular visits to observation half a year with or without recurrence.

Treat three groups: this organizes 80 people, adopt the honey of the embodiment of the present invention 3 refining pill to treat.In menstrual cycle the 5th day, each 1 ball, every day twice, was used in conjunction 5 days courses for the treatment of.Treat that next menstrual cycle 5 days is a course for the treatment of again.Continue to carry out three courses for the treatment of.Observe latter 6 months for the treatment of.And follow up a case by regular visits to observation half a year with or without recurrence.

Matched group: this organizes 80 people, adopts QI and blood and capsule to treat.Oral, one time 4,2 times on the one, a menstrual cycle is a course for the treatment of, starts to take through the last week, continues to carry out 3 courses for the treatment of.Observe latter 6 months for the treatment of.And follow up a case by regular visits to observation half a year with or without recurrence.

The standard of curative effect evaluation:

Cure: recover normal through amount, maintain more than 3 months.

Take a turn for the better: through amount showed increased.Or recover normal through amount, but can not more than 3 months be maintained.

Do not heal: through cycle, unchanged through measuring.

Therapeutic outcome:

Table 1 is the treatment contrast for the treatment of by Chinese herbs group and western medicine group

As can be seen from Table 1, the healing number of three treatment groups is all higher than matched group, therefore, can learn, medicine of the present invention, in treatment renal deficiency type hypomenorrhea, good effect, determined curative effect, cure and improvement rate high.

Table 2 is the time contrast of the healing for the treatment of group and matched group and the sum of improvement:

Group	Number of cases	1st course for the treatment of	2nd course for the treatment of	3rd course for the treatment of
					Treat one group	80	50（62.5%)	20(25%)	10（12.5%）
Treat two groups	80	48（60%）	22（27.5%）	10（12.5%）
					Treat three groups	80	51（63.75%）	20（25%）	9（11.25%）
Matched group	65	10(15.38%)	20(30.77%)	35（53.85%）

As can be seen from Table 2, the healing of three treatment groups is compared with matched group with improvement number, and the short time just can occur curative effect.Can learn, medicine of the present invention, in treatment renal deficiency type hypomenorrhea, curative effect is fast, and rapid-action, treatment time is shorter.

Table 3 is the recurrence contrast of the healing for the treatment of group and matched group::

Group	Cure	Recurrence number	Relapse rate
				Treat one group	78	0	0%
Treat two groups	77	0	0%
				Treat three groups	78	0	0%
Matched group	60	5	8.33%

As can be seen from Table 3, compare after the recovery from illness of three treatment groups with matched group, recurrence number is few, and relapse rate is low.Can learn, medicine of the present invention, in treatment renal deficiency type hypomenorrhea, good effect, not easily recurs.

To sum up learn, medicine of the present invention is being treated in deficiency of the kidney type hypomenorrhea, good effect, and determined curative effect is rapid-action, not easily recurs.

Model case:

Patient Lee, female, 27 years old, married, be renal deficiency type hypomenorrhea in first visit on March 10 in 2012.Symptom is for few through carrying out amount, and namely clean within the next few days, color is light dim, and matter is rare, waist soreness, dizziness and tinnitus, frequent micturition, light red tongue, thin fur, deep-thready pulse.The oral solutions of the embodiment of the present invention 2 is adopted to treat.In menstrual cycle the 5th day, each 15ml, every day twice, was used in conjunction 5 days courses for the treatment of.Treat that next menstrual cycle 5 days is a course for the treatment of again.Continue to carry out three courses for the treatment of.Observe latter 6 months for the treatment of.All can meet the deadline after treatment and rise, menstrual blood volume is normal, and each symptom all disappears, and cures.Follow up a case by regular visits to half a year, do not recur again.

The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims

1. treat the medicine of renal deficiency type hypomenorrhea for one kind, it is characterized in that, described medicine comprises following raw medicinal material: Placenta Hominis, the Cortex Eucommiae, Semen Astragali Complanati, Gecko, Cornu Cervi Pantotrichum, Hippocampus, Testis et penis callorhini, Radix Rehmanniae Preparata, Arillus Longan, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati, Fructus Lycii, Fructus Ligustri Lucidi, Carapax Et Plastrum Testudinis, Flos Rosae Rugosae, Herba Aristolochiae, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Caulis Spatholobi, Testis Caprae seu Ovis, Aeschna melanictera, Carnis Elaphuri davidiani, Fructus rubi tephrodis, Air Bladder pseudosciaenae seu Acipenser, Spongilla, Semen glycines sojae, Caulis Cucurbitae, rose hip, Radix Phyllagathis fordii.

2. medicine according to claim 1, is characterized in that, in described medicine, the ratio of weight and number of each raw medicinal material is: Placenta Hominis 10-23 weight portion, Cortex Eucommiae 10-20 weight portion, Semen Astragali Complanati 15-22 weight portion, Gecko 10-19 weight portion, Cornu Cervi Pantotrichum 12-26 weight portion, Hippocampus 10-18 weight portion, Testis et penis callorhini 10-20 weight portion, Radix Rehmanniae Preparata 13-24 weight portion, Arillus Longan 15-27 weight portion, Radix Asparagi 10-20 weight portion, Herba Dendrobii 14-25 weight portion, Rhizoma Polygonati 10-20 weight portion, Fructus Lycii 12-20 weight portion, Fructus Ligustri Lucidi 12-26 weight portion, Carapax Et Plastrum Testudinis 10-18 weight portion, Flos Rosae Rugosae 15-30 weight portion, Herba Aristolochiae 13-27 weight portion, Radix Salviae Miltiorrhizae 10-24 weight portion, Radix Achyranthis Bidentatae 12-24 weight portion, Caulis Spatholobi 10-20 weight portion, Testis Caprae seu Ovis 10-18 weight portion, Aeschna melanictera 10-18 weight portion, Carnis Elaphuri davidiani 10-20 weight portion, Fructus rubi tephrodis 12-18 weight portion, Air Bladder pseudosciaenae seu Acipenser 10-24 weight portion, Spongilla 12-25 weight portion, Semen glycines sojae 10-20 weight portion, Caulis Cucurbitae 14-27 weight portion, rose hip 10-23 weight portion and Radix Phyllagathis fordii 10-20 weight portion.

3. medicine according to claim 1 and 2, is characterized in that, in described medicine, the ratio of weight and number of each raw medicinal material is: Placenta Hominis 15-23 weight portion, Cortex Eucommiae 15-20 weight portion, Semen Astragali Complanati 18-22 weight portion, Gecko 14-19 weight portion, Cornu Cervi Pantotrichum 12-20 weight portion, Hippocampus 14-18 weight portion, Testis et penis callorhini 15-20 weight portion, Radix Rehmanniae Preparata 13-20 weight portion, Arillus Longan 15-20 weight portion, Radix Asparagi 15-20 weight portion, Herba Dendrobii 14-20 weight portion, Rhizoma Polygonati 15-20 weight portion, Fructus Lycii 18-20 weight portion, Fructus Ligustri Lucidi 12-20 weight portion, Carapax Et Plastrum Testudinis 10-13 weight portion, Flos Rosae Rugosae 25-30 weight portion, Herba Aristolochiae 13-20 weight portion, Radix Salviae Miltiorrhizae 15-24 weight portion, Radix Achyranthis Bidentatae 18-24 weight portion, Caulis Spatholobi 15-20 weight portion, Testis Caprae seu Ovis 15-18 weight portion, Aeschna melanictera 14-18 weight portion, Carnis Elaphuri davidiani 15-20 weight portion, Fructus rubi tephrodis 15-18 weight portion, Air Bladder pseudosciaenae seu Acipenser 15-24 weight portion, Spongilla 12-20 weight portion, Semen glycines sojae 15-20 weight portion, Caulis Cucurbitae 14-20 weight portion, rose hip 16-23 weight portion and Radix Phyllagathis fordii 16-20 weight portion.

4. the medicine according to any one of claim 1-3, it is characterized in that, in described medicine, the ratio of weight and number of each raw medicinal material is: Placenta Hominis 13 weight portion, the Cortex Eucommiae 14 weight portion, Semen Astragali Complanati 15 weight portion, Gecko 10 weight portion, Cornu Cervi Pantotrichum 26 weight portion, Hippocampus 10 weight portion, Testis et penis callorhini 10 weight portion, Radix Rehmanniae Preparata 24 weight portion, Arillus Longan 27 weight portion, Radix Asparagi 12 weight portion, Herba Dendrobii 25 weight portion, Rhizoma Polygonati 12 weight portion, Fructus Lycii 14 weight portion, Fructus Ligustri Lucidi 26 weight portion, Carapax Et Plastrum Testudinis 18 weight portion, Flos Rosae Rugosae 15 weight portion, Herba Aristolochiae 27 weight portion, Radix Salviae Miltiorrhizae 12 weight portion, Radix Achyranthis Bidentatae 13 weight portion, Caulis Spatholobi 12 weight portion, Testis Caprae seu Ovis 13 weight portion, Aeschna melanictera 12 weight portion, Carnis Elaphuri davidiani 12 weight portion, Fructus rubi tephrodis 12 weight portion, Air Bladder pseudosciaenae seu Acipenser 12 weight portion, Spongilla 25 weight portion, Semen glycines sojae 14 weight portion, Caulis Cucurbitae 27 weight portion, rose hip 13 weight portion and Radix Phyllagathis fordii 14 weight portion.

5. the medicine according to any one of claim 1-4, it is characterized in that, in described medicine, the ratio of weight and number of each raw medicinal material is: Placenta Hominis 23 weight portion, the Cortex Eucommiae 20 weight portion, Semen Astragali Complanati 22 weight portion, Gecko 19 weight portion, Cornu Cervi Pantotrichum 20 weight portion, Hippocampus 18 weight portion, Testis et penis callorhini 20 weight portion, Radix Rehmanniae Preparata 20 weight portion, Arillus Longan 20 weight portion, Radix Asparagi 20 weight portion, Herba Dendrobii 20 weight portion, Rhizoma Polygonati 20 weight portion, Fructus Lycii 20 weight portion, Fructus Ligustri Lucidi 20 weight portion, Carapax Et Plastrum Testudinis 13 weight portion, Flos Rosae Rugosae 30 weight portion, Herba Aristolochiae 20 weight portion, Radix Salviae Miltiorrhizae 24 weight portion, Radix Achyranthis Bidentatae 24 weight portion, Caulis Spatholobi 20 weight portion, Testis Caprae seu Ovis 18 weight portion, Aeschna melanictera 18 weight portion, Carnis Elaphuri davidiani 20 weight portion, Fructus rubi tephrodis 18 weight portion, Air Bladder pseudosciaenae seu Acipenser 24 weight portion, Spongilla 20 weight portion, Semen glycines sojae 20 weight portion, Caulis Cucurbitae 20 weight portion, rose hip 23 weight portion and Radix Phyllagathis fordii 20 weight portion.

6. the medicine according to any one of claim 1-5, is characterized in that, when the dosage form of described medicine is capsule, its preparation method is:

7. the medicine according to any one of claim 1-5, is characterized in that, when the dosage form of described medicine is oral solutions, its preparation method is:

8. a preparation method for the medicine described in any one of claim 1-5, is characterized in that, the dosage form of described medicine is capsule, and its preparation method is:

9. a preparation method for the medicine described in any one of claim 1-5, is characterized in that, when the dosage form of described medicine is oral solutions, its preparation method is:

10. the medicine according to any one of claim 1-5, it is characterized in that, the dosage form of described medicine is: sugar coated tablet, film coated tablet, enteric coated tablet, hard capsule, soft capsule, oral liquid, suck agent, granule, electuary, honey pill agent, powder, sublimed preparation, solution, injection, suppository, plaster, syrup, powder, liniment, enema and patch.