CN105902611A - Preparation method of kudzuvine root medicinal slices applicable to diarrhea disease of spleen deficiency - Google Patents
Preparation method of kudzuvine root medicinal slices applicable to diarrhea disease of spleen deficiency Download PDFInfo
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- CN105902611A CN105902611A CN201610406127.2A CN201610406127A CN105902611A CN 105902611 A CN105902611 A CN 105902611A CN 201610406127 A CN201610406127 A CN 201610406127A CN 105902611 A CN105902611 A CN 105902611A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Alternative & Traditional Medicine (AREA)
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Abstract
The invention discloses a preparation method of kudzuvine root medicinal slices applicable to a diarrhea disease of spleen deficiency. The method comprises the following steps of purifying, cooking, sized dicing, microwaves, bran manufacturing and screening. The obtained kudzuvine root is slightly yellow and uniform in color, free of focal spot and fragrant, and a water alcohol extract, general flavone, puerarin and the like are increased to different extents compared with a traditional preparation method; compared with a traditional wheat bran frying method, the puerarin content is improved by 11%, the general flavone content is improved by 13%, the quality of medicinal slices is stable, and the curative effect on the diarrhea disease of spleen deficiency is good.
Description
Technical field
The present invention relates to Chinese crude drug manufacture field, be specifically related to the concocting method of a kind of Radix Puerariae decoction pieces being applicable to diarrhea due to hypofunction of the spleen disease.
Background technology
Radix Puerariae is the dry root of legume pueraria lobata.Radix Puerariae is good at expelling pathogenic factors from muscles for reducing heat, rash, promotes the production of body fluid.It is used for thirsty, the measles of calentura etc..The disperse function of roasted RADIX PUERARIAE is mitigated, and enhances diarrhea-relieving function, is used for damp-heat dysentery, diarrhea due to hypofunction of the spleen.As Qing Dynasty doctor Zhang Bingcheng is sayed in " book on Chinese herbal medicine is just read ", " simmer ripe, dissipating property completely without, i.e. entered intestinal, the table of not all right negative and positive by stomach, but enter sun bright in, the lucid yang sending up is use, and also the stewing such as Rhizoma Cimicifugae is ripe, i.e. liter and do not dissipate, can be with intestines strengthening and diarrhea checking ear.Radix Puerariae is simmered big gun at bran and is processed in technique, and traditional heating means are parches, but the effective content of drug effect components of Radix Puerariae that this method is concocted is relatively low, and effect can not meet requirement.
Summary of the invention
It is an object of the invention to provide the concocting method of a kind of Radix Puerariae decoction pieces being applicable to diarrhea due to hypofunction of the spleen disease, high for the effective component extraction rate in Radix Puerariae.
For realizing object above, the present invention is achieved by the following technical programs:
The concocting method of a kind of Radix Puerariae decoction pieces being applicable to diarrhea due to hypofunction of the spleen disease, comprises the following steps:
1) only make: fresh Radix Puerariae is cleaned, remove the earth on surface, sandstone and non-medicinal effects；
2) decoct: the Radix Puerariae after step 1) only being made is placed in herbal medicine immersion tank, it is added thereto to equipped with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Fructus Mume, the Chinese medicine accessory package of Poria, add water to exceed material liquid surface 10cm, soak 20-30min, decoct 1-2h, Chinese medicine accessory package is taken out, continue little fire and decoct until fried these receipts of liquid-based are done, take out Radix Puerariae, cooling；
3) pelletizing: by step 2) decoct after Radix Puerariae be cut into little side's grain；
4) microwave: add the ethanol solution of 70%, ultrasonic 5-10min in the Radix Puerariae after step 3) pelletizing, then put it into and carry out microwave heating 3-5min in microwave oven；
5) bran system: add Testa Tritici, mix homogeneously in the Radix Puerariae after step 4) microwave, bake；
6) sieve: after having baked, be cooled to room temperature, sieve, Testa Tritici is separated with Radix Puerariae, to obtain final product.
Preferably, in described step 1) Chinese medicine accessory package, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Fructus Mume, the mass ratio of Poria are 6:7:5:6:4:7.
Preferably, in described step 1), the mass ratio of Radix Puerariae and Chinese medicine accessory package is 3-4:2.
Preferably, in described step 4), supersonic frequency is 30-50KHz.
Preferably, in described step 4), microwave frequency is 1500-2000MHz.
Preferably, baked temperature 110-130 DEG C in described step 5), baking time 60-90min.
Beneficial effect: the present invention is by Radix Puerariae and Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Chinese crude drugs such as the Radix Aucklandiae decoct together, it is favorably improved the active ingredient of Radix Puerariae, strengthen its invigorating spleen and reinforcing stomach, the effect of sending up the lucid YANG, by microwave again after ultrasonic for Radix Puerariae, cell is had breaking cellular wall effect, it is beneficial to the extraction of active substance, the present invention concocts the micro-Huang of Radix Puerariae color and luster obtained, uniformly, without focal spot, there is fragrance, its water alcohol extract, total flavones, more traditional concocting method such as puerarin all has raising in various degree, compared to tradition Testa Tritici frying production method, puerarin content improves 11%, general flavone content improves 13%, prepared slice quality is stable, good therapeutic effect is had for diarrhea due to hypofunction of the spleen disease.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that, described embodiment is a part of embodiment of the present invention rather than whole embodiments.Based on the embodiment in the present invention, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, broadly fall into the scope of protection of the invention.
Embodiment
1
:
The concocting method of a kind of Radix Puerariae decoction pieces being applicable to diarrhea due to hypofunction of the spleen disease, comprises the following steps:
1) only make: fresh Radix Puerariae is cleaned, remove the earth on surface, sandstone and non-medicinal effects；
2) decoct: the Radix Puerariae after step 1) only being made is placed in herbal medicine immersion tank, being added thereto to Chinese medicine accessory package, the mass ratio of Radix Puerariae and Chinese medicine accessory package is 3:2, equipped with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Fructus Mume, Poria in Chinese medicine accessory package, its mass ratio is 6:7:5:6:4:7, in herbal medicine immersion tank, add water to exceed material liquid surface 10cm, soak 25min, decoct 1.5h, Chinese medicine accessory package is taken out, continue little fire to decoct until fried these receipts of liquid-based are done, take out Radix Puerariae, cooling；
3) pelletizing: by step 2) decoct after Radix Puerariae be cut into little side's grain；
4) microwave: adding the ethanol solution of 70%, ultrasonic 7min in the Radix Puerariae after step 3) pelletizing, supersonic frequency is 40KHz, then puts it into and carry out microwave heating 4min in microwave oven, and microwave frequency is 1800MHz；
5) bran system: add Testa Tritici, mix homogeneously, baking time 80min under conditions of 120 DEG C in the Radix Puerariae after step 4) microwave；
6) sieve: after having baked, be cooled to room temperature, sieve, Testa Tritici is separated with Radix Puerariae, to obtain final product.
Embodiment
2
:
The concocting method of a kind of Radix Puerariae decoction pieces being applicable to diarrhea due to hypofunction of the spleen disease, comprises the following steps:
1) only make: fresh Radix Puerariae is cleaned, remove the earth on surface, sandstone and non-medicinal effects；
2) decoct: the Radix Puerariae after step 1) only being made is placed in herbal medicine immersion tank, being added thereto to Chinese medicine accessory package, the mass ratio of Radix Puerariae and Chinese medicine accessory package is 2:1, equipped with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Fructus Mume, Poria in Chinese medicine accessory package, its mass ratio is 6:7:5:6:4:7, in herbal medicine immersion tank, add water to exceed material liquid surface 10cm, soak 20min, decoct 1h, Chinese medicine accessory package is taken out, continue little fire to decoct until fried these receipts of liquid-based are done, take out Radix Puerariae, cooling；
3) pelletizing: by step 2) decoct after Radix Puerariae be cut into little side's grain；
4) microwave: adding the ethanol solution of 70%, ultrasonic 5min in the Radix Puerariae after step 3) pelletizing, supersonic frequency is 50KHz, then puts it into and carry out microwave heating 3min in microwave oven, and microwave frequency is 2000MHz；
5) bran system: add Testa Tritici, mix homogeneously, baking time 90min under conditions of 110 DEG C in the Radix Puerariae after step 4) microwave；
6) sieve: after having baked, be cooled to room temperature, sieve, Testa Tritici is separated with Radix Puerariae, to obtain final product.
Embodiment
3
:
The concocting method of a kind of Radix Puerariae decoction pieces being applicable to diarrhea due to hypofunction of the spleen disease, comprises the following steps:
1) only make: fresh Radix Puerariae is cleaned, remove the earth on surface, sandstone and non-medicinal effects；
2) decoct: the Radix Puerariae after step 1) only being made is placed in herbal medicine immersion tank, being added thereto to Chinese medicine accessory package, the mass ratio of Radix Puerariae and Chinese medicine accessory package is 3:2, equipped with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Fructus Mume, Poria in Chinese medicine accessory package, its mass ratio is 6:7:5:6:4:7, in herbal medicine immersion tank, add water to exceed material liquid surface 10cm, soak 30min, decoct 1.5h, Chinese medicine accessory package is taken out, continue little fire to decoct until fried these receipts of liquid-based are done, take out Radix Puerariae, cooling；
3) pelletizing: by step 2) decoct after Radix Puerariae be cut into little side's grain；
4) microwave: adding the ethanol solution of 70%, ultrasonic 10min in the Radix Puerariae after step 3) pelletizing, supersonic frequency is 30KHz, then puts it into and carry out microwave heating 5min in microwave oven, and microwave frequency is 1500MHz；
5) bran system: add Testa Tritici, mix homogeneously, baking time 60min under conditions of 130 DEG C in the Radix Puerariae after step 4) microwave；
6) sieve: after having baked, be cooled to room temperature, sieve, Testa Tritici is separated with Radix Puerariae, to obtain final product.
Embodiment
4
:
The concocting method of a kind of Radix Puerariae decoction pieces being applicable to diarrhea due to hypofunction of the spleen disease, comprises the following steps:
1) only make: fresh Radix Puerariae is cleaned, remove the earth on surface, sandstone and non-medicinal effects；
2) decoct: the Radix Puerariae after step 1) only being made is placed in herbal medicine immersion tank, being added thereto to Chinese medicine accessory package, the mass ratio of Radix Puerariae and Chinese medicine accessory package is 2:1, equipped with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Fructus Mume, Poria in Chinese medicine accessory package, its mass ratio is 6:7:5:6:4:7, in herbal medicine immersion tank, add water to exceed material liquid surface 10cm, soak 25min, decoct 2h, Chinese medicine accessory package is taken out, continue little fire to decoct until fried these receipts of liquid-based are done, take out Radix Puerariae, cooling；
3) pelletizing: by step 2) decoct after Radix Puerariae be cut into little side's grain；
4) microwave: adding the ethanol solution of 70%, ultrasonic 10min in the Radix Puerariae after step 3) pelletizing, supersonic frequency is 50KHz, then puts it into and carry out microwave heating 4min in microwave oven, and microwave frequency is 1700MHz；
5) bran system: add Testa Tritici, mix homogeneously, baking time 60min under conditions of 130 DEG C in the Radix Puerariae after step 4) microwave；
6) sieve: after having baked, be cooled to room temperature, sieve, Testa Tritici is separated with Radix Puerariae, to obtain final product.
To sum up, the embodiment of the present invention has the advantages that
It should be noted that, in this article, the relational terms of such as first and second or the like is used merely to separate an entity or operation with another entity or operating space, and not necessarily requires or imply the relation or sequentially that there is any this reality between these entities or operation.And, term " includes ", " comprising " or its any other variant are intended to comprising of nonexcludability, so that include that the process of a series of key element, method, article or equipment not only include those key elements, but also include other key elements being not expressly set out, or also include the key element intrinsic for this process, method, article or equipment.In the case of there is no more restriction, statement " including ... " key element limited, it is not excluded that there is also other identical element in including the process of described key element, method, article or equipment.
Above example only in order to technical scheme to be described, is not intended to limit；Although the present invention being described in detail with reference to previous embodiment, it will be understood by those within the art that: the technical scheme described in foregoing embodiments still can be modified by it, or wherein portion of techniques feature is carried out equivalent；And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (6)
1. the concocting method of the Radix Puerariae decoction pieces being applicable to diarrhea due to hypofunction of the spleen disease, it is characterised in that comprise the following steps:
1) only make: fresh Radix Puerariae is cleaned, remove the earth on surface, sandstone and non-medicinal effects；
2) decoct: the Radix Puerariae after step 1) only being made is placed in herbal medicine immersion tank, it is added thereto to equipped with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Fructus Mume, the Chinese medicine accessory package of Poria, add water to exceed material liquid surface 10cm, soak 20-30min, decoct 1-2h, Chinese medicine accessory package is taken out, continue little fire and decoct until fried these receipts of liquid-based are done, take out Radix Puerariae, cooling；
3) pelletizing: by step 2) decoct after Radix Puerariae be cut into little side's grain；
4) microwave: add the ethanol solution of 70%, ultrasonic 5-10min in the Radix Puerariae after step 3) pelletizing, then put it into and carry out microwave heating 3-5min in microwave oven；
5) bran system: add Testa Tritici, mix homogeneously in the Radix Puerariae after step 4) microwave, bake；
6) sieve: after having baked, be cooled to room temperature, sieve, Testa Tritici is separated with Radix Puerariae, to obtain final product.
It is applicable to the concocting method of the Radix Puerariae decoction pieces of diarrhea due to hypofunction of the spleen disease the most as claimed in claim 1, it is characterised in that in described step 1) Chinese medicine accessory package, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Fructus Mume, the mass ratio of Poria are 6:7:5:6:4:7.
It is applicable to the concocting method of the Radix Puerariae decoction pieces of diarrhea due to hypofunction of the spleen disease the most as claimed in claim 1, it is characterised in that in described step 1), the mass ratio of Radix Puerariae and Chinese medicine accessory package is 3-4:2.
It is applicable to the concocting method of the Radix Puerariae decoction pieces of diarrhea due to hypofunction of the spleen disease the most as claimed in claim 1, it is characterised in that in described step 4), supersonic frequency is 30-50KHz.
It is applicable to the concocting method of the Radix Puerariae decoction pieces of diarrhea due to hypofunction of the spleen disease the most as claimed in claim 1, it is characterised in that in described step 4), microwave frequency is 1500-2000MHz.
It is applicable to the concocting method of the Radix Puerariae decoction pieces of diarrhea due to hypofunction of the spleen disease the most as claimed in claim 1, it is characterised in that baked temperature 110-130 DEG C in described step 5), baking time 60-90min.
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| CN201610406127.2A CN105902611A (en) | 2016-06-12 | 2016-06-12 | Preparation method of kudzuvine root medicinal slices applicable to diarrhea disease of spleen deficiency |
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| CN201610406127.2A CN105902611A (en) | 2016-06-12 | 2016-06-12 | Preparation method of kudzuvine root medicinal slices applicable to diarrhea disease of spleen deficiency |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107568735A (en) * | 2017-11-06 | 2018-01-12 | 德兴市宋氏葛业有限公司 | A kind of preparation method of superminiature kudzuvine root starch |
| CN110403977A (en) * | 2018-04-27 | 2019-11-05 | 江西江中中药饮片有限公司 | The preparation method and application of pueraria lobata micro mist |
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| CN1559528A (en) * | 2004-02-25 | 2005-01-05 | 江苏康缘药业股份有限公司 | Medicine for treating child diarrhea and its preparation method |
| CN102068522A (en) * | 2009-11-25 | 2011-05-25 | 冯科 | Medicinal composition for treating infantile diarrhea and preparation method thereof |
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2016
- 2016-06-12 CN CN201610406127.2A patent/CN105902611A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1559528A (en) * | 2004-02-25 | 2005-01-05 | 江苏康缘药业股份有限公司 | Medicine for treating child diarrhea and its preparation method |
| CN102068522A (en) * | 2009-11-25 | 2011-05-25 | 冯科 | Medicinal composition for treating infantile diarrhea and preparation method thereof |
Non-Patent Citations (2)
| Title |
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| 王和平等: "烘制麸葛根的实验研究", 《中成药》 * |
| 王文化 等: "浅谈半夏的炮制方法与临床药用", 《淮海医药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107568735A (en) * | 2017-11-06 | 2018-01-12 | 德兴市宋氏葛业有限公司 | A kind of preparation method of superminiature kudzuvine root starch |
| CN110403977A (en) * | 2018-04-27 | 2019-11-05 | 江西江中中药饮片有限公司 | The preparation method and application of pueraria lobata micro mist |
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Application publication date: 20160831 |