CN105899495B - 用于治疗疼痛和其它病症的γ-氨基丁酸(GABA)类似物 - Google Patents
用于治疗疼痛和其它病症的γ-氨基丁酸(GABA)类似物 Download PDFInfo
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- CN105899495B CN105899495B CN201480069317.9A CN201480069317A CN105899495B CN 105899495 B CN105899495 B CN 105899495B CN 201480069317 A CN201480069317 A CN 201480069317A CN 105899495 B CN105899495 B CN 105899495B
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
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- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
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- Orthopedic Medicine & Surgery (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910061968.8A CN109721562A (zh) | 2013-12-18 | 2014-12-16 | 用于治疗疼痛和其它病症的γ-氨基丁酸(GABA)类似物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361917623P | 2013-12-18 | 2013-12-18 | |
| US61/917,623 | 2013-12-18 | ||
| PCT/EP2014/077937 WO2015091463A1 (en) | 2013-12-18 | 2014-12-16 | Gamma-aminobutyric acid (gaba) analogues for the treatment of pain and other disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910061968.8A Division CN109721562A (zh) | 2013-12-18 | 2014-12-16 | 用于治疗疼痛和其它病症的γ-氨基丁酸(GABA)类似物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105899495A CN105899495A (zh) | 2016-08-24 |
| CN105899495B true CN105899495B (zh) | 2019-02-19 |
Family
ID=52278595
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480069317.9A Active CN105899495B (zh) | 2013-12-18 | 2014-12-16 | 用于治疗疼痛和其它病症的γ-氨基丁酸(GABA)类似物 |
| CN201910061968.8A Pending CN109721562A (zh) | 2013-12-18 | 2014-12-16 | 用于治疗疼痛和其它病症的γ-氨基丁酸(GABA)类似物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910061968.8A Pending CN109721562A (zh) | 2013-12-18 | 2014-12-16 | 用于治疗疼痛和其它病症的γ-氨基丁酸(GABA)类似物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9663479B2 (https=) |
| EP (1) | EP3083572B1 (https=) |
| JP (1) | JP6491213B2 (https=) |
| KR (1) | KR102031334B1 (https=) |
| CN (2) | CN105899495B (https=) |
| AU (1) | AU2014364693B2 (https=) |
| CA (1) | CA2932050C (https=) |
| RU (1) | RU2679407C1 (https=) |
| WO (1) | WO2015091463A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6491213B2 (ja) * | 2013-12-18 | 2019-03-27 | ノヴァッセイ エスエー | 疼痛および他の障害の治療のためのガンマ−アミノ酪酸(gaba)類似体 |
| CN107667097B (zh) * | 2015-05-27 | 2021-02-12 | 诺瓦色生物公司 | 3-乙基双环[3.2.0]庚-3-烯-6-酮的对映体的分离 |
| CN110818582B (zh) * | 2019-11-20 | 2023-06-09 | 合肥拓锐生物科技有限公司 | 一种gaba类似物及其盐,及其合成方法、应用、药物 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1133045A (zh) * | 1993-04-01 | 1996-10-09 | 弗吉尼亚大学 | 作为止痛药和消炎药的7-氮杂双环[2,2,1]-庚烷和庚烯衍生物 |
| EP1199072A2 (en) * | 2000-10-17 | 2002-04-24 | Warner-Lambert Company | Method of treating cartilage damage |
| CN101878193A (zh) * | 2007-09-28 | 2010-11-03 | 第一三共株式会社 | 双环γ-氨基酸衍生物 |
| US20120329781A1 (en) * | 2003-09-12 | 2012-12-27 | Pfizer Inc | Combinations comprising alpha-2-delta ligands |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19508459A1 (de) * | 1995-03-09 | 1996-09-12 | Wacker Chemie Gmbh | Verfahren zur Herstellung von Alkylsilanen mit sperrigen Alkylresten |
| CN1131855C (zh) * | 1997-12-16 | 2003-12-24 | 沃尼尔·朗伯公司 | 1-取代-1-氨基甲基-环烷衍生物(=加巴喷丁类似物)、其制备及其在治疗神经病方面的用途 |
| WO2010079668A1 (ja) | 2009-01-08 | 2010-07-15 | 第一三共株式会社 | オレフィン化合物 |
| JP5557292B2 (ja) | 2009-03-26 | 2014-07-23 | 第一三共株式会社 | 二環性γ−アミノ酸誘導体の製造方法 |
| CN104755465A (zh) * | 2012-08-24 | 2015-07-01 | 武田药品工业株式会社 | 杂环化合物 |
| TWI635071B (zh) * | 2013-07-08 | 2018-09-11 | 第一三共股份有限公司 | 光學活性二環γ-胺基酸衍生物及其製造方法 |
| JP6491213B2 (ja) * | 2013-12-18 | 2019-03-27 | ノヴァッセイ エスエー | 疼痛および他の障害の治療のためのガンマ−アミノ酪酸(gaba)類似体 |
-
2014
- 2014-12-16 JP JP2016540644A patent/JP6491213B2/ja not_active Expired - Fee Related
- 2014-12-16 CN CN201480069317.9A patent/CN105899495B/zh active Active
- 2014-12-16 KR KR1020167019522A patent/KR102031334B1/ko active Active
- 2014-12-16 US US15/106,139 patent/US9663479B2/en active Active - Reinstated
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2016
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1133045A (zh) * | 1993-04-01 | 1996-10-09 | 弗吉尼亚大学 | 作为止痛药和消炎药的7-氮杂双环[2,2,1]-庚烷和庚烯衍生物 |
| EP1199072A2 (en) * | 2000-10-17 | 2002-04-24 | Warner-Lambert Company | Method of treating cartilage damage |
| US20120329781A1 (en) * | 2003-09-12 | 2012-12-27 | Pfizer Inc | Combinations comprising alpha-2-delta ligands |
| CN101878193A (zh) * | 2007-09-28 | 2010-11-03 | 第一三共株式会社 | 双环γ-氨基酸衍生物 |
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| CA2932050A1 (en) | 2015-06-25 |
| CA2932050C (en) | 2023-09-26 |
| WO2015091463A1 (en) | 2015-06-25 |
| EP3083572B1 (en) | 2019-02-13 |
| KR102031334B1 (ko) | 2019-10-11 |
| US9750720B2 (en) | 2017-09-05 |
| US9663479B2 (en) | 2017-05-30 |
| JP2017502020A (ja) | 2017-01-19 |
| KR20160095166A (ko) | 2016-08-10 |
| EP3083572A1 (en) | 2016-10-26 |
| US20160318885A1 (en) | 2016-11-03 |
| US20170071909A1 (en) | 2017-03-16 |
| CN109721562A (zh) | 2019-05-07 |
| AU2014364693A1 (en) | 2016-07-28 |
| AU2014364693B2 (en) | 2018-12-06 |
| CN105899495A (zh) | 2016-08-24 |
| JP6491213B2 (ja) | 2019-03-27 |
| RU2679407C1 (ru) | 2019-02-08 |
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