CN105899192B - 药物递送用载体、偶联物及含有这些成分的组合物以及它们的施予方法 - Google Patents
药物递送用载体、偶联物及含有这些成分的组合物以及它们的施予方法 Download PDFInfo
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- CN105899192B CN105899192B CN201480063806.3A CN201480063806A CN105899192B CN 105899192 B CN105899192 B CN 105899192B CN 201480063806 A CN201480063806 A CN 201480063806A CN 105899192 B CN105899192 B CN 105899192B
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910638349.0A CN110302394A (zh) | 2013-11-22 | 2014-11-21 | 药物递送用载体、偶联物及含有这些成分的组合物以及它们的施予方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013-242347 | 2013-11-22 | ||
| JP2013242347 | 2013-11-22 | ||
| JP2014096935 | 2014-05-08 | ||
| JP2014-096935 | 2014-05-08 | ||
| PCT/JP2014/005856 WO2015075942A1 (ja) | 2013-11-22 | 2014-11-21 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910638349.0A Division CN110302394A (zh) | 2013-11-22 | 2014-11-21 | 药物递送用载体、偶联物及含有这些成分的组合物以及它们的施予方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105899192A CN105899192A (zh) | 2016-08-24 |
| CN105899192B true CN105899192B (zh) | 2019-08-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480063806.3A Expired - Fee Related CN105899192B (zh) | 2013-11-22 | 2014-11-21 | 药物递送用载体、偶联物及含有这些成分的组合物以及它们的施予方法 |
| CN201910638349.0A Pending CN110302394A (zh) | 2013-11-22 | 2014-11-21 | 药物递送用载体、偶联物及含有这些成分的组合物以及它们的施予方法 |
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| EP3072506B1 (en) * | 2013-11-22 | 2022-04-20 | The University of Tokyo | Carrier for drug delivery and conjugate, composition containing same, and method for administering same |
| JP6797415B2 (ja) * | 2015-07-02 | 2020-12-09 | 国立大学法人 東京大学 | 薬剤送達用キャリア及びこれを含む組成物 |
| EP3492512A4 (en) * | 2016-07-30 | 2020-04-08 | Nippon Kayaku Kabushiki Kaisha | NEW POLYMER DERIVATIVES, AND NEW POLYMER DERIVATIVE IMAGING PROBE USING SAID NEW POLYMER DERIVATIVES |
| JP7043078B2 (ja) * | 2016-09-23 | 2022-03-29 | 国立大学法人 東京医科歯科大学 | 血液脳関門通過型ヘテロ2本鎖核酸 |
| US11364259B2 (en) * | 2016-12-27 | 2022-06-21 | The University Of Tokyo | MRNA functionalization method |
| WO2018207864A1 (ja) * | 2017-05-11 | 2018-11-15 | 公益財団法人川崎市産業振興財団 | 脳への薬剤送達用のキャリアおよびこれを含んでなる組成物 |
| JPWO2019009434A1 (ja) * | 2017-07-06 | 2020-07-02 | 学校法人京都薬科大学 | 薬物送達用高分子ミセル |
| JP2019069933A (ja) * | 2017-10-05 | 2019-05-09 | 公益財団法人川崎市産業振興財団 | 体内における薬物動態を制御する組成物 |
| WO2019181946A1 (ja) | 2018-03-19 | 2019-09-26 | 国立大学法人東京医科歯科大学 | 毒性が軽減した核酸 |
| JPWO2019240223A1 (ja) * | 2018-06-13 | 2021-07-01 | 公益財団法人川崎市産業振興財団 | 数平均分子量が3kDa〜10kDaであるPEGブロックとカチオン性ポリマーとのブロックコポリマーと、アンチセンスオリゴヌクレオチドとを含む、ポリイオンコンプレックスミセル |
| JPWO2020116635A1 (ja) * | 2018-12-07 | 2021-10-21 | 国立大学法人 東京大学 | 輸送担体を用いた環状化合物の送達 |
| JP7600101B2 (ja) | 2019-04-26 | 2024-12-16 | 公益財団法人川崎市産業振興財団 | 抗体の抗原結合性断片を脳へ送達するための方法および組成物 |
| WO2020230793A1 (ja) * | 2019-05-13 | 2020-11-19 | 国立大学法人東京大学 | 血中からの中空ナノ粒子の脳への移行制御技術 |
| WO2021193393A1 (en) * | 2020-03-26 | 2021-09-30 | Kawasaki Institute Of Industrial Promotion | A method of administering a nanoparticle |
| WO2021207382A1 (en) * | 2020-04-08 | 2021-10-14 | The Johns Hopkins University | D-glucose and its analogs as tracers to assess the glucose transporter function |
| US20250073349A1 (en) | 2021-05-10 | 2025-03-06 | Kawasaki Institute Of Industrial Promotion | Antibody having reduced binding affinity for antigen |
| JP2024536844A (ja) * | 2021-09-25 | 2024-10-08 | ヌタリア リミテッド | 処置様式のための標的封入戦略 |
| WO2023210233A1 (ja) * | 2022-04-27 | 2023-11-02 | 国立大学法人東海国立大学機構 | 糖連結ポリヌクレオチド |
| WO2025221757A1 (en) * | 2024-04-15 | 2025-10-23 | Board Of Regents, The University Of Texas System | Carbohydrate-polymer conjugates for tunable protein binding on the blood brain barrier and methods of use |
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| BRPI0619605B8 (pt) | 2005-12-12 | 2021-05-25 | Hoffmann La Roche | composições compreendendo moléculas de anticorpos contra amilóide beta4 com glicosilação na região variável, usos das mesmas, método de preparação de uma molécula de anticorpo, e kit |
| US8765172B2 (en) * | 2007-12-10 | 2014-07-01 | Epitarget As | Acoustically sensitive drug delivery particles comprising non-lamellar forming lipids |
| EP2382994A1 (en) * | 2010-04-26 | 2011-11-02 | Maurizio Victor Cattaneo | Ligand targeted nanocapsules for the delivery of RNAi and other agents |
| JP5843763B2 (ja) | 2010-05-21 | 2016-01-13 | 国立研究開発法人科学技術振興機構 | 物質内包ベシクル及びその製造方法 |
| EP3072506B1 (en) * | 2013-11-22 | 2022-04-20 | The University of Tokyo | Carrier for drug delivery and conjugate, composition containing same, and method for administering same |
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| CN102256952A (zh) * | 2008-12-19 | 2011-11-23 | 伊莱利利公司 | 用作葡萄糖激酶激活剂的芳基环丙基乙酰胺衍生物 |
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| Blood-brain barrier glucose transporter:effects of hypo- and hyperglycemia revisited;SIMPSON IA.et al.;<<Journal of Neurochemistry>>;19991231;第72卷;第4823-4824页 * |
| Design, synthesis and biological evaluation of multivalent glucosides with high affinity as ligands for brain targeting liposomes;QU B.et al.;<<European Journal of Medicinal Chemistry>>;20131120;第72卷;文章摘要,第110-115页 * |
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| CN105899192A (zh) | 2016-08-24 |
| JP2017105802A (ja) | 2017-06-15 |
| US9937263B2 (en) | 2018-04-10 |
| JP6086566B2 (ja) | 2017-03-01 |
| JPWO2015075942A1 (ja) | 2017-03-16 |
| EP3072506B1 (en) | 2022-04-20 |
| EP3072506A1 (en) | 2016-09-28 |
| CA2931056C (en) | 2023-02-28 |
| JP6782415B2 (ja) | 2020-11-11 |
| US10912838B2 (en) | 2021-02-09 |
| CN110302394A (zh) | 2019-10-08 |
| CA2931056A1 (en) | 2015-05-28 |
| EP3072506A4 (en) | 2017-10-11 |
| US20160287714A1 (en) | 2016-10-06 |
| JP2019194220A (ja) | 2019-11-07 |
| WO2015075942A1 (ja) | 2015-05-28 |
| US20180185501A1 (en) | 2018-07-05 |
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