CN105873569B - 用于化疗剂、核酸和光敏剂的递送或共递送的纳米级载体 - Google Patents

用于化疗剂、核酸和光敏剂的递送或共递送的纳米级载体 Download PDF

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CN105873569B
CN105873569B CN201480072258.0A CN201480072258A CN105873569B CN 105873569 B CN105873569 B CN 105873569B CN 201480072258 A CN201480072258 A CN 201480072258A CN 105873569 B CN105873569 B CN 105873569B
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sirna
ncp
lipid
cisplatin
porphyrin
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CN105873569A (zh
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林文斌
何春柏
刘德敏
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University of Chicago
University of North Carolina at Chapel Hill
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CN201480072258.0A 2013-11-06 2014-11-06 用于化疗剂、核酸和光敏剂的递送或共递送的纳米级载体 Active CN105873569B (zh)

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US201361900698P 2013-11-06 2013-11-06
US61/900,698 2013-11-06
PCT/US2014/064388 WO2015069926A1 (en) 2013-11-06 2014-11-06 Nanoscale carriers for the delivery or co-delivery of chemotherapeutics, nucleic acids and photosensitizers

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CN105873569B true CN105873569B (zh) 2020-07-28

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US (2) US10517822B2 (enExample)
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US11246877B2 (en) 2016-05-20 2022-02-15 The University Of Chicago Nanoparticles for chemotherapy, targeted therapy, photodynamic therapy, immunotherapy, and any combination thereof
US11826426B2 (en) 2017-08-02 2023-11-28 The University Of Chicago Nanoscale metal-organic layers and metal-organic nanoplates for x-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof
US11872311B2 (en) 2011-07-08 2024-01-16 The University Of North Carolina At Chapel Hill Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders

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WO2014066834A1 (en) * 2012-10-26 2014-05-01 The University Of Chicago Synergistic combination of immunologic inhibitors for the treatment of cancer
WO2015149068A1 (en) 2014-03-28 2015-10-01 The University Of Chicago Chiral ligand-based metal-organic frameworks for broad-scope asymmetric catalysis
US10647733B2 (en) 2014-03-28 2020-05-12 The University Of Chicago Metal-organic frameworks containing nitrogen-donor ligands for efficient catalytic organic transformations
US10806694B2 (en) 2014-10-14 2020-10-20 The University Of Chicago Nanoparticles for photodynamic therapy, X-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof
EP3206987B2 (en) 2014-10-14 2024-07-24 The University of Chicago Nanoparticles for photodynamic therapy, x-ray induced photodynamic therapy, radiotherapy, chemotherapy, immunotherapy, and any combination thereof
AU2015230812A1 (en) * 2015-09-25 2017-04-13 The University Of Sydney Treatment and prevention of adrenocortical carcinoma
US10953393B2 (en) 2015-10-12 2021-03-23 The University Of Chicago Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations
WO2017192573A1 (en) 2016-05-02 2017-11-09 Massachusetts Institute Of Technology Nanoparticle conjugates of highly potent toxins and intraperitoneal administration of nanoparticles for treating or imaging cancer
EP3474987A4 (en) 2016-08-18 2020-01-08 The University of Chicago METAL CATALYSTS SUPPORTED BY A METAL OXIDE AND ABUNDANT IN THE EARTH FOR HIGHLY EFFICIENT ORGANIC TRANSFORMATIONS
WO2018067431A1 (en) * 2016-10-03 2018-04-12 Purdue Research Foundation Re-sensitizing drug-resistant cancer cells by combinational therapy
CN108318311B (zh) * 2017-01-15 2022-01-18 复旦大学 一种硬骨特异性钙质荧光染色方法及其应用
CN106947010B (zh) * 2017-04-06 2018-12-11 哈尔滨工业大学 一种利用光引发raft聚合原位诱导自组装制备蛋白质基纳米粒子的方法
CN107142281A (zh) * 2017-06-07 2017-09-08 东华大学 聚酰胺‑胺树状大分子与纳米金颗粒的复合物作为非病毒载体进行基因转染的应用方法
CN109554397A (zh) * 2017-09-26 2019-04-02 广州宏柯源生物科技有限公司 纳米颗粒及其制备方法
CN107753946B (zh) * 2017-10-23 2020-11-27 福州大学 一种适配体修饰的靶向载药纳米粒及其制备方法与应用
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CN111526857B (zh) * 2017-12-21 2023-07-04 H&A帕玛科株式会社 利用金属-有机骨架材料和纳米纤维素的用于透皮递送的复合物
US20190314324A1 (en) 2018-04-13 2019-10-17 The University Of Chicago Combination of micheliolide derivatives or nanoparticles with ionizing radiation and checkpoint inhibitors for cancer therapy
CN108619511B (zh) * 2018-04-20 2020-12-15 山东大学 一种基于阿糖胞苷小分子前药的金属有机框架载药系统的制备方法和应用
CN108794532A (zh) * 2018-05-18 2018-11-13 东北林业大学 脑磷脂类似物、制备方法及用途
CN111110846B (zh) * 2018-10-30 2021-07-23 国家纳米科学中心 一种金属-核酸纳米颗粒及其制备方法和用途
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