CN105816700A - 一种外敷治疗烫烧伤软膏 - Google Patents

一种外敷治疗烫烧伤软膏 Download PDF

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CN105816700A
CN105816700A CN201610176456.2A CN201610176456A CN105816700A CN 105816700 A CN105816700 A CN 105816700A CN 201610176456 A CN201610176456 A CN 201610176456A CN 105816700 A CN105816700 A CN 105816700A
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黄钰雯
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Abstract

本发明公开了一种外敷治疗烫烧伤软膏,其由质量份的以下原料组成:轮藻15~20份、紫珠10~15份、大蓟5~10份、芦荟3~5份、紫草3~5份、五倍子2~5份、大黄3~5份、芦苇1~5份、铁皮石斛2~7份、氮酮1~2份、麻油200~250份、蜂蜡20~30份、对羟基苯甲酸乙酯0.01~1份。本发明原料为纯天然的中草药,无毒副作用,将多种中草药复配,具有止血凉血、清热解毒、活血化瘀、消肿敛疮、养阴生津等功效,对烫烧伤的治疗有显著效果。

Description

一种外敷治疗烫烧伤软膏
技术领域
本发明涉及药品技术领域,具体涉及一种外敷治疗烫烧伤软膏。
背景技术
烫烧伤是指由于热力或热液体所引起的组织损害,主要是指皮肤或粘膜的损害,严重者可伤及皮下组织。烫烧伤存在着创面疼痛、进行性坏死、易感染、瘢痕愈合等四大难题。近代中医文献认为烫烧伤是因热所致,热盛则内腐,以致肌肤腐烂,外毒有内功的可能,故认为除热外还有毒,其病因机制还是热毒,治疗上多采用清热解毒的中药外用试剂或方药,但烧烫伤症中的“热”与一般的温热病的“火、热”不尽相同,烫烧伤主要侵犯中焦,多为阳明实热之证,热邪为病耗阴损气,但烧烫伤有伤口,必有淤血凝滞,伤口多腐肉脓血,故一般烫烧伤的治疗原则应该包括以下治则:清热解毒、养阴生津、益气理脾、活血除淤、托里排脓。
发明内容
本发明的目的在于,针对现有技术,提供一种外敷治疗烫烧伤软膏。
为实现上述目的,本发明采取以下技术方案:一种外敷治疗烫烧伤软膏,其由质量份的以下原料组成:轮藻15~20份、紫珠10~15份、大蓟5~10份、芦荟3~5份、紫草3~5份、五倍子2~5份、大黄3~5份、芦苇1~5份、铁皮石斛2~7份、氮酮1~2份、麻油200~250份、蜂蜡20~30份、对羟基苯甲酸乙酯0.01~1份。
优选的,一种外敷治疗烫烧伤软膏由质量份的以下原料组成:轮藻18份、紫珠12份、大蓟8份、芦荟4份、紫草4份、五倍子4份、大黄4份、芦苇4份、铁皮石斛5份、氮酮1份、麻油200份、蜂蜡20份、对羟基苯甲酸乙酯0.05份。
其制备方法为:将轮藻、紫珠、大蓟、紫草、五倍子、大黄、芦苇、芦荟、铁皮石斛浸泡于10~12倍质量的80~85%乙醇溶液浸泡4h,加热回流提取三次,静置、过滤、将滤液减压回收乙醇,浓缩、在温度为70~80℃、气压为0.05Mpa下真空干燥,再进行超微粉碎成浸膏粉备用,称取质量份的麻油加热至80~82℃,加入质量份的蜂蜡熔融、过滤备用;取质量份的羟基苯甲酸乙酯和氮酮,加入乙醇溶解,再加入麻油、蜂蜡熔融液中搅拌均匀,加热至无醇味,加入上述各药粉,搅拌至冷凝。
其中,轮藻具有疏风清热、利湿止咳,可治愈风热感冒,烫烧伤等症。
其中,芦荟具有泻火、解毒、化瘀、杀虫等功效,还具有杀菌、抗炎作用,芦荟浆汁对皮肤创伤、烧伤以及x线局部照射均有保护作用。
其中,大黄主要的药用成分为蒽醌,芪、萘衍生物、鞣质及游离没食子酸、桂皮酸、酯类等,具有清热解毒、抗菌消炎、泻火凉血的功效。
其中,芦苇具有清热生津、除烦镇呕、清凉解毒、防脑炎、止血解毒等功效。
其中,大蓟性凉,味甘,苦,具有凉血止血、祛瘀消肿的功效。
其中,紫草味苦,性寒,具有凉血活血,清热解毒。
其中,五倍子,胃酸、涩,性寒,具有敛肺降火、涩肠止泻,敛汗止血,收湿敛疮的功效,可用于便血痔血、外伤出血、臃肿疮毒、皮肤湿烂。
其中,铁皮石斛,味甘,性微寒,具有生津养胃,滋阴清热,抗炎消炎,增强免疫功能等功效。
其中,氮酮为皮肤渗透助剂,麻油、对羟甲苯丙酸乙酯、蜂蜡混合共溶为油液,为本发明的药物基质。
本发明的有益效果是:本发明原料为纯天然的中草药,无毒副作用,将多种中草药复配,具有止血凉血、清热解毒、活血化瘀、消肿敛疮、养阴生津等功效,对烫烧伤的治疗有显著效果。
具体实施方式
下面结合具体实施例,对本发明进一步的说明。
实施例1
一种外敷治疗烫烧伤软膏由质量份的以下原料组成:轮藻18份、紫珠12份、大蓟8份、芦荟4份、紫草4份、五倍子4份、大黄4份、芦苇4份、铁皮石斛5份、氮酮1份、麻油200份、蜂蜡20份、对羟基苯甲酸乙酯0.05份。
其制备方法为:将轮藻、紫珠、大蓟、紫草、五倍子、大黄、芦苇、芦荟、铁皮石斛浸泡于11倍质量的82%乙醇溶液中,浸泡4h,加热回流提取三次,静置、过滤、将滤液减压回收乙醇,浓缩、在温度为75℃、气压为0.05Mpa下真空干燥,再进行超微粉碎成浸膏粉备用,称取质量份的麻油加热至81℃,加入质量份的蜂蜡熔融、过滤备用;取质量份的羟基苯甲酸乙酯和氮酮,加入乙醇溶解,再加入麻油、蜂蜡熔融液中搅拌均匀,加热至无醇味,加入上述各药粉,搅拌至冷凝。
实施例2
一种外敷治疗烫烧伤软膏由质量份的以下原料组成:轮藻20份、紫珠15份、大蓟10份、芦荟5份、紫草5份、五倍子5份、大黄5份、芦苇5份、铁皮石斛7份、氮酮2份、麻油250份、蜂蜡30份、对羟基苯甲酸乙酯1份。
其制备方法为:将轮藻、紫珠、大蓟、紫草、五倍子、大黄、芦苇、芦荟、铁皮石斛浸泡于12倍质量的85%乙醇溶液中,浸泡4h,加热回流提取三次,静置、过滤、将滤液减压回收乙醇,浓缩、在温度为80℃、气压为0.05Mpa下真空干燥,再进行超微粉碎成浸膏粉备用,称取质量份的麻油加热至82℃,加入质量份的蜂蜡熔融、过滤备用;取质量份的羟基苯甲酸乙酯和氮酮,加入乙醇溶解,再加入麻油、蜂蜡熔融液中搅拌均匀,加热至无醇味,加入上述各药粉,搅拌至冷凝。
实施例3
一种外敷治疗烫烧伤软膏由质量份的以下原料组成:轮藻15份、紫珠10份、大蓟5份、芦荟3份、紫草3份、五倍子2份、大黄3份、芦苇1份、铁皮石斛2份、氮酮1份、麻油200份、蜂蜡20份、对羟基苯甲酸乙酯0.01份。
进一步的,本发明的用于风热感冒的冲剂的制备方法为:将轮藻、紫珠、大蓟、紫草、五倍子、大黄、芦苇、芦荟、铁皮石斛浸泡于10倍质量的80%乙醇溶液中,浸泡4h,加热回流提取三次,静置、过滤、将滤液减压回收乙醇,浓缩、在温度为70℃、气压为0.05Mpa下真空干燥,再进行超微粉碎成浸膏粉备用,称取质量份的麻油加热至80℃,加入质量份的蜂蜡熔融、过滤备用;取质量份的羟基苯甲酸乙酯和氮酮,加入乙醇溶解,再加入麻油、蜂蜡熔融液中搅拌均匀,加热至无醇味,加入上述各药粉,搅拌至冷凝。

Claims (2)

1.一种外敷治疗烫烧伤软膏,其特征在于,其由质量份的以下原料组成:轮藻15~20份、紫珠10~15份、大蓟5~10份、芦荟3~5份、紫草3~5份、五倍子2~5份、大黄3~5份、芦苇1~5份、铁皮石斛2~7份、氮酮1~2份、麻油200~250份、蜂蜡20~30份、对羟基苯甲酸乙酯0.01~1份。
2.根据权利要求1所述的一种外敷治疗烫烧伤软膏,其特征在于,其制备方法为:将轮藻、紫珠、大蓟、紫草、五倍子、大黄、芦苇、芦荟、铁皮石斛进浸泡于10~12倍质量的80~85%乙醇溶液中,浸泡4h,加热回流提取三次,静置、过滤、将滤液减压回收乙醇,浓缩、在温度为70~80℃、气压为0.05Mpa下真空干燥,再进行超微粉碎成浸膏粉备用,称取质量份的麻油加热至80~82℃,加入质量份的蜂蜡熔融、过滤备用;取质量份的羟基苯甲酸乙酯和氮酮,加入乙醇溶解,再加入麻油、蜂蜡熔融液中搅拌均匀,加热至无醇味,加入上述各药粉,搅拌至冷凝。
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1985899A (zh) * 2006-12-26 2007-06-27 刘永敦 一种治疗烧烫伤的外用药物及其制备方法
CN102100772A (zh) * 2011-01-18 2011-06-22 纪俊兴 烫烧伤软膏

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1985899A (zh) * 2006-12-26 2007-06-27 刘永敦 一种治疗烧烫伤的外用药物及其制备方法
CN102100772A (zh) * 2011-01-18 2011-06-22 纪俊兴 烫烧伤软膏

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GOALAHEAD: "中国烧伤大全(梁勇才编著)", 《爱问共享资料HTTP://ISHARE.IASK.SINA.COM.CN/F/9048409.HTML》 *
张猛等: "轮藻培养条件初探", 《广东农业科》 *

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