CN105816462A - 可可碱的药物组合及其在治疗中的用途 - Google Patents
可可碱的药物组合及其在治疗中的用途 Download PDFInfo
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- CN105816462A CN105816462A CN201610214436.XA CN201610214436A CN105816462A CN 105816462 A CN105816462 A CN 105816462A CN 201610214436 A CN201610214436 A CN 201610214436A CN 105816462 A CN105816462 A CN 105816462A
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- agent
- theobromine
- pseudoephedrine
- effective amount
- therapeutically effective
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- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0921805.8 | 2009-12-14 | ||
| GBGB0921805.8A GB0921805D0 (en) | 2009-12-14 | 2009-12-14 | Drug composition and its use in therapy |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800570306A Division CN102740843A (zh) | 2009-12-14 | 2010-12-14 | 可可碱与解充血剂的组合及其用于治疗咳嗽的用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105816462A true CN105816462A (zh) | 2016-08-03 |
Family
ID=41667045
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610214436.XA Pending CN105816462A (zh) | 2009-12-14 | 2010-12-14 | 可可碱的药物组合及其在治疗中的用途 |
| CN2010800570306A Pending CN102740843A (zh) | 2009-12-14 | 2010-12-14 | 可可碱与解充血剂的组合及其用于治疗咳嗽的用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800570306A Pending CN102740843A (zh) | 2009-12-14 | 2010-12-14 | 可可碱与解充血剂的组合及其用于治疗咳嗽的用途 |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP2512464A1 (https=) |
| JP (2) | JP2013513651A (https=) |
| CN (2) | CN105816462A (https=) |
| AU (1) | AU2010332494B2 (https=) |
| BR (1) | BR112012014161A2 (https=) |
| CA (1) | CA2784214C (https=) |
| CO (1) | CO6541630A2 (https=) |
| EC (1) | ECSP12012132A (https=) |
| GB (1) | GB0921805D0 (https=) |
| IL (1) | IL220383A (https=) |
| MX (1) | MX343222B (https=) |
| NZ (1) | NZ600243A (https=) |
| PE (1) | PE20121537A1 (https=) |
| PH (1) | PH12012501203A1 (https=) |
| RU (1) | RU2564904C2 (https=) |
| SG (2) | SG10201408377QA (https=) |
| UA (1) | UA105944C2 (https=) |
| WO (1) | WO2011073646A1 (https=) |
| ZA (1) | ZA201204293B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201111485D0 (en) * | 2011-07-05 | 2011-08-17 | Biocopea Ltd | Drug composition and its use in therapy |
| US10016437B2 (en) | 2009-06-16 | 2018-07-10 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| US9314465B2 (en) | 2009-06-16 | 2016-04-19 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| GB0910375D0 (en) | 2009-06-16 | 2009-07-29 | Biocopea Ltd | Drug composition and its use in therapy |
| US9308211B2 (en) | 2009-06-16 | 2016-04-12 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995007103A1 (en) * | 1993-09-07 | 1995-03-16 | The Procter & Gamble Company | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive |
| HUP9700654A2 (hu) | 1997-03-26 | 1999-09-28 | Dezső Korbonits | Teobromin tartalmú köhögéscsillapító készítmények |
| US6417206B1 (en) * | 2001-01-26 | 2002-07-09 | Medpointe Healthcare Inc. | Antitussive/antihist aminic/decongestant compositions |
| JP2002308761A (ja) * | 2001-04-09 | 2002-10-23 | Taisho Pharmaceut Co Ltd | 風邪用咳止め薬 |
| JP2003128549A (ja) * | 2001-08-15 | 2003-05-08 | Rohto Pharmaceut Co Ltd | 粘膜適用組成物 |
| JP4377564B2 (ja) * | 2002-05-02 | 2009-12-02 | ロート製薬株式会社 | 内服用組成物 |
| RU2311919C2 (ru) * | 2002-12-30 | 2007-12-10 | Каунсел Оф Сайнтифик Энд Индастриал Рисерч | Разработка противокашлевой и смягчающей горло травяной композиции |
| US20040202677A1 (en) * | 2003-04-10 | 2004-10-14 | Hopkins Kevin J. | Method of enhanced regional body fat reduction |
| US20060153926A1 (en) * | 2005-01-10 | 2006-07-13 | Bascom Charles C | Compositions, products and methods for controlling weight in a mammal |
| US20080003280A1 (en) * | 2006-06-26 | 2008-01-03 | Levine Brian M | Combination cough treatment compounds and method of treating common coughs |
| CN100518775C (zh) * | 2007-03-16 | 2009-07-29 | 邓丽菊 | 一种治疗咳喘的药物组合物及其制剂 |
-
2009
- 2009-12-14 GB GBGB0921805.8A patent/GB0921805D0/en not_active Ceased
-
2010
- 2010-12-14 AU AU2010332494A patent/AU2010332494B2/en not_active Ceased
- 2010-12-14 CA CA2784214A patent/CA2784214C/en not_active Expired - Fee Related
- 2010-12-14 UA UAA201208706A patent/UA105944C2/uk unknown
- 2010-12-14 RU RU2012129839/15A patent/RU2564904C2/ru not_active IP Right Cessation
- 2010-12-14 WO PCT/GB2010/052085 patent/WO2011073646A1/en not_active Ceased
- 2010-12-14 PH PH1/2012/501203A patent/PH12012501203A1/en unknown
- 2010-12-14 CN CN201610214436.XA patent/CN105816462A/zh active Pending
- 2010-12-14 SG SG10201408377QA patent/SG10201408377QA/en unknown
- 2010-12-14 MX MX2012006625A patent/MX343222B/es active IP Right Grant
- 2010-12-14 EP EP10795446A patent/EP2512464A1/en not_active Ceased
- 2010-12-14 CN CN2010800570306A patent/CN102740843A/zh active Pending
- 2010-12-14 SG SG2012043642A patent/SG181686A1/en unknown
- 2010-12-14 BR BR112012014161A patent/BR112012014161A2/pt not_active IP Right Cessation
- 2010-12-14 PE PE2012000813A patent/PE20121537A1/es not_active Application Discontinuation
- 2010-12-14 NZ NZ600243A patent/NZ600243A/xx not_active IP Right Cessation
- 2010-12-14 JP JP2012543902A patent/JP2013513651A/ja active Pending
-
2012
- 2012-06-12 EC ECSP12012132 patent/ECSP12012132A/es unknown
- 2012-06-12 CO CO12098537A patent/CO6541630A2/es unknown
- 2012-06-12 ZA ZA2012/04293A patent/ZA201204293B/en unknown
- 2012-06-13 IL IL220383A patent/IL220383A/en not_active IP Right Cessation
-
2015
- 2015-09-28 JP JP2015189231A patent/JP2016040279A/ja active Pending
Non-Patent Citations (2)
| Title |
|---|
| MINAMIZAWA K 等: "Effect of d-Pseudoephedrine on Cough Reflex and Its Mode of Action in Guinea Pigs", 《JOURNAL OF PHARMACOLOGICAL SCIENCE》 * |
| USMANI OS 等: "Theobromine ibhibits sensory nerve activation and cough", 《THE FASEB JOURNAL》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013513651A (ja) | 2013-04-22 |
| PH12012501203A1 (en) | 2012-11-05 |
| EP2512464A1 (en) | 2012-10-24 |
| SG10201408377QA (en) | 2015-02-27 |
| PE20121537A1 (es) | 2012-12-21 |
| NZ600243A (en) | 2013-07-26 |
| RU2012129839A (ru) | 2014-01-27 |
| SG181686A1 (en) | 2012-07-30 |
| ECSP12012132A (es) | 2012-09-28 |
| IL220383A0 (en) | 2012-08-30 |
| IL220383A (en) | 2017-01-31 |
| BR112012014161A2 (pt) | 2016-05-17 |
| AU2010332494A1 (en) | 2012-06-14 |
| JP2016040279A (ja) | 2016-03-24 |
| GB0921805D0 (en) | 2010-01-27 |
| ZA201204293B (en) | 2013-02-27 |
| CA2784214C (en) | 2018-01-09 |
| WO2011073646A1 (en) | 2011-06-23 |
| MX2012006625A (es) | 2012-10-05 |
| CN102740843A (zh) | 2012-10-17 |
| RU2564904C2 (ru) | 2015-10-10 |
| CO6541630A2 (es) | 2012-10-16 |
| CA2784214A1 (en) | 2011-06-23 |
| UA105944C2 (uk) | 2014-07-10 |
| MX343222B (es) | 2016-10-28 |
| AU2010332494B2 (en) | 2015-01-15 |
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| CB02 | Change of applicant information |
Address after: London, England Applicant after: INFIRST HEALTHCARE LIMITED Address before: London, England Applicant before: INFIRST HEALTHCARE LIMITED |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160803 |
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| RJ01 | Rejection of invention patent application after publication |