CN105796974A - Feed additive for treating self-biting disease of minks and preparation method thereof - Google Patents
Feed additive for treating self-biting disease of minks and preparation method thereof Download PDFInfo
- Publication number
- CN105796974A CN105796974A CN201610280844.5A CN201610280844A CN105796974A CN 105796974 A CN105796974 A CN 105796974A CN 201610280844 A CN201610280844 A CN 201610280844A CN 105796974 A CN105796974 A CN 105796974A
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- parts
- radix
- feed additive
- mink
- self
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Landscapes
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a feed additive for treating self-biting disease of minks and a preparation method thereof. The feed additive is prepared from the following ingredients: acanthopanax root, mothers of pearl, dens draconis, goat horns, Ludisia discolor, radix paeoniae rubra, cynanchum atratum, spina gleditsiae, eucalyptus leaves, citrus aurantium, red roses, flowers of silktree albizzia, Cortex Sophorae, radix astragali, red halloysite, honey, pine needle meal, shrimp meal, rice bran, silkworm chrysalis, fish scale and olive oil. The feed additive disclosed by the invention can be used for effectively treating canine distemper of the minks and is low in drug residue, good in treatment effect, high in cure rate and low in toxic or side effects, the cure recovery period is shortened, the food intake of the minks is increased, the use is convenient, and the economic benefit of farmers is increased.
Description
Technical field
The present invention relates to a kind of feed additive, be specifically related to a kind of feed additive treating Mink Self-Biting Disease, the preparation method that the invention still further relates to this feed additive.
Background technology
Standard mink skin is the fur coat of a kind of preciousness, and kind color is varied, expensive, has the laudatory title of " king of fur coat ".From the quality of standard mink skin and value, its utilization rate is also above the big capillary skin such as Vulpes, raccoon fur, and especially domestic market potentiality are very big.Standard mink skin is straight and upright with its pin hair, flexibly magnificent, fine hair is abundant, warmth retention property is strong, dermatotome is frivolous, pliable and tough solid and famous, be the primary raw material skin making clothes, collar, medicated cap, cuff and decorations mouth, utilize face relatively wide, demand is also big.And the big capillary skin such as Vulpes, raccoon fur, owing to lint relatively standard mink skin is slightly long, magnificent not as good as standard mink skin, domestic market is not suitable for overcoat processed, and is only suitable for making the ornaments such as collar, cuff, tippet, therefore utilization rate relatively standard mink skin is low.As can be seen here, the development prospect of the little capillary skin animal based on mink is better than the big capillary skin animal such as Vulpes, Nyctereutes procyonoides.
Self-biting disease is a kind of chronic disease being feature with regular excitement, oneself health part that bites that food meat fur-bearing animal occurs.At excitation time, ill domestic animal often bites certain position of oneself health, stings bad fur, and severe patient may result in septicemia, finally dead because of extreme exhaustion.Because of the generation of self-biting disease, result in the destruction of mink hide, grade decline, it has also become one of outstanding problem in mink farming industry.Current people are clear not enough to the pathogenesis of self-biting disease, and There are many different versions of a story for Chinese scholars.Therefore the classification of this disease is defined also without clear and definite.Recent year thinks that Nutrition and Metabolism disease, nervous system disease, viral infectious cause more.In addition, after mink rear quarters is wet by water or disinfectant immersion, cold wind is attacked and is produced skin allergy, and mink rear quarters, afterbody occur that scabies and ill also can the bringing out of skin are stung certainly.
Summary of the invention
It is an object of the invention to provide a kind of feed additive treating Mink Self-Biting Disease and preparation method thereof, the feed additive of the present invention can effectively treat mink canine distemper, medicine is residual few, good effect, cure rate is high, and toxic and side effects is low, shorten and recover convalescent period, improve mink dietary amount, easy to use, improve the economic benefit of raiser.
To achieve these goals, present invention provide the technical scheme that
A kind of feed additive treating Mink Self-Biting Disease, is made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 20-30 part, Concha Margaritifera 10-20 part, Dens Draconis 9-15 part, Cornu Naemorhedi 4-10 part, Herba Ludisiae Discoloris 6-10 part, Radix Paeoniae Rubra 6-12 part, Radix Cynanchi Atrati 10-15 part, Spina Gleditsiae 6-10 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 5-15 part, Citrus aurantium L. var. amara Engl. 3-9 part, Flos Rosae Rugosae 4-10 part, Flos Albiziae 5-10 part, Cortex sophorae 8-16 part, Radix Astragali 10-20 part, Halloysitum Rubrum 8-12 part, Mel 8-16 part, pine needle powder 8-12 part, shrimp meal 10-20 part, Testa oryzae 4-10 part, Pupa bombycis 5-9 part, fish scale 4-8 part, olive oil 3-7 part.
Further, a kind of feed additive treating Mink Self-Biting Disease, is made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 20 parts, Concha Margaritifera 10 parts, Dens Draconis 9 parts, Cornu Naemorhedi 4 parts, Herba Ludisiae Discoloris 6 parts, Radix Paeoniae Rubra 6 parts, Radix Cynanchi Atrati 10 parts, Spina Gleditsiae 6 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 5 parts, Citrus aurantium L. var. amara Engl. 3 parts, Flos Rosae Rugosae 4 parts, Flos Albiziae 5 parts, Cortex sophorae 8 parts, the Radix Astragali 10 parts, Halloysitum Rubrum 8 parts, Mel 8 parts, pine needle powder 8 parts, shrimp meal 10 parts, 4 parts of Testa oryzae, Pupa bombycis 5 parts, 4 parts of fish scale, 3 parts of olive oil.
Further, a kind of feed additive treating Mink Self-Biting Disease, is made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 30 parts, Concha Margaritifera 20 parts, Dens Draconis 15 parts, Cornu Naemorhedi 10 parts, Herba Ludisiae Discoloris 10 parts, Radix Paeoniae Rubra 12 parts, Radix Cynanchi Atrati 15 parts, Spina Gleditsiae 10 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 15 parts, Citrus aurantium L. var. amara Engl. 9 parts, Flos Rosae Rugosae 10 parts, Flos Albiziae 10 parts, Cortex sophorae 16 parts, the Radix Astragali 20 parts, Halloysitum Rubrum 12 parts, Mel 16 parts, pine needle powder 12 parts, shrimp meal 20 parts, 10 parts of Testa oryzae, Pupa bombycis 9 parts, 8 parts of fish scale, 7 parts of olive oil.
Further, a kind of feed additive treating Mink Self-Biting Disease, is made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 25 parts, Concha Margaritifera 15 parts, Dens Draconis 12 parts, Cornu Naemorhedi 7 parts, Herba Ludisiae Discoloris 8 parts, Radix Paeoniae Rubra 9 parts, Radix Cynanchi Atrati 12 parts, Spina Gleditsiae 8 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, Citrus aurantium L. var. amara Engl. 6 parts, Flos Rosae Rugosae 7 parts, Flos Albiziae 8 parts, Cortex sophorae 12 parts, the Radix Astragali 15 parts, Halloysitum Rubrum 10 parts, Mel 12 parts, pine needle powder 10 parts, shrimp meal 15 parts, 7 parts of Testa oryzae, Pupa bombycis 7 parts, 6 parts of fish scale, 5 parts of olive oil.
Fang Zhong:
Radix Et Caulis Acanthopanacis Senticosi: medicinal part is the root of Araliaceae Radix Et Caulis Acanthopanacis Senticosi, rhizome or stem and leaf.Mildly bitter flavor, pungent, warm in nature.Return spleen, kidney, heart channel.Replenishing kidney, strengthening waist, benefiting vital QI for tranquillizing, promoting blood circulation to remove obstruction in the collateral.Main kidney deficiency and bodily weakness, soreness of the waist and knees, children's's walking retardation in children, insufficiency of the spleen weak, deficiency of vital energy edema, inappetence, insomnia and dreamful sleep, forgetful, thoracic obstruction pain, anemofrigid-damp arthralgia, treating swelling and pain by traumatic injury.For deficiency of spleen-YANG and kidneyYANG, body void is weak, inappetence, soreness of waist and knee joint, insomnia and dreamful sleep；Concha Margaritifera: basis, medicine source is the shell of Unionidae animal hydriopsis cumingii, cristaria plicata or Pteriidae animal Pteria martensii Dunker.Salty, cold.Return liver, heart channel.Suppressing the hyperactive liver, YANG hyperactivity suppressing, calm the nerves, arresting convulsion, hemostasis.Control dizziness, tinnitus, cardiopalmus, have a sleepless night, demented, infantile convulsion, spit blood, epistaxis, metrorrhagia；Dens Draconis: for for ancient times mammal as if the fossil of tooth of class, rhinoceros class, Hippocampal cortex etc..Sweet puckery, cool.Enter the heart, Liver Channel.Tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, stop blooding astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Controlling infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen, and tells nosebleed and has blood in stool, and bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time；Cornu Naemorhedi: for cattle and sheep section horn.Salty in the mouth, cold in nature.GUIXIN, Liver Channel." Jilin Chinese herbal medicine ": " calm, bring down a fever, improving eyesight, hemostasis.Control pediatric epilepsy scared, headache, puerperal abdonimal pain, dysmenorrhoea.”；Herba Ludisiae Discoloris: medicinal part is the herb of the orchid family blood aspidistra platymiscium blood aspidistra.Sweet in the mouth, cool in nature.Return lung, spleen channel.Removing heat from blood, hemostasis, nourishing YIN and moistening the lung.Spit blood for pulmonary tuberculosis, neurasthenia；Radix Paeoniae Rubra: medicinal part is ranunculaceae plant Radix Paeoniae Rubra or the dry root of river Radix Paeoniae Rubra.Bitter in the mouth, cold nature.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection；Radix Cynanchi Atrati: bitter salty, cold.Enter lung, stomach, kidney channel.Clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment.For pathogenic warmth wound battalion heating, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, puerperal fever due to deficiency of blood, pyretic stranguria, stranguria with blood, swollen ulcer drug.Knife injury；Spina Gleditsiae: medicinal part is the dry Spina jujubae of leguminous plant Fructus Gleditsia.Acrid in the mouth, warm in nature.Return liver, stomach warp.Detumescence poison holding, evacuation of pus, parasite killing.For carbuncle from the beginning of or difficulty in discharging of pus；External treatment scabies leprosy；Folium eucalypti globueli (Eucalyptus globulus Labill.): medicinal part is the leaf of myrtle Eucalyptus globulus Labill.Bitter, acrid, cold.Return lung, stomach, spleen, Liver Channel.Dispelling wind to relieve the exterior syndrome, heat-clearing and toxic substances removing, killing parasites for relieving itching.Cure mainly flu, high heat headache, lung-heat cough with asthma, pertussis, abdominal distention, dysentery of suffering from diarrhoea, ancylostome filaricide, malaria, rheumatalgia, ulcerative carbuncle toxic swelling, eczema scabies, burn and scald, traumatic hemorrhage；Citrus aurantium L. var. amara Engl.: medicinal part is the alabastrum of Folium Symplocoris Caudatae profit plant Citrus aurantium L. var. amara Engl.." pharmacognosy ": " sweet micro-hardship.”；Promoting the circulation of QI to alleviate the stagnation in middle-JIAO, helps digestion, and reduces phlegm.For the vexed distending pain of chest and abdomen, accumulation of food in the stomach and intes tine due to indigestion, phlegm retention, proctoptosis, soothing the liver, stomach function regulating, regulate the flow of vital energy.Control painful abdominal mass in the heart vexed, abdominal distention, vomiting, few food；Flos Rosae Rugosae: medicinal part is the dry flower of rosaceous plant Flos Rosae Rugosae.Hardship sweet, micro-, temperature.Return liver, spleen channel.Promoting QI circulation for relieving depression, and blood, pain relieving.For stomachache due to hyperactive liver-QI attacking the stomach, lack of appetite vomiting and nausea, menoxenia, fall and flutter the pain of injury；Flos Albiziae: medicinal part is the dry inflorescence of leguminous plant Herba Albiziae.Nature and flavor are sweet, flat.Shu Yu, regulate the flow of vital energy, calm the nerves, active, nourish blood, YIN nourishing kidney, clear away heart-fire improving eyesight.Control pent-up uncomfortable in chest, insomnia, forgetful, acute conjunctivitis, can settling five organs, and will, improving healthy complexion, have keep fit preferably, calm, the effect calming the nerves, improve looks, be the neurasthenic good merchantable brand for the treatment of.Having clearing away summer-heat, face-beautifying and spot-removing such as relieves the effect of alcohol at the effect；Cortex sophorae: basis, medicine source is the phloem of the bark of leguminous plant Chinese scholartree or root bark." property of medicine opinion ": " bitter in the mouth, nontoxic." " detailed outline ": " and bitter, flat, nontoxic." expelling wind and removing dampness, reducing swelling and alleviating pain.Control in outside ailment said due to cold or exposure, orthotonus, numbness of the skin, calentura aphtha, ulcerative gingivitis, sore throat, discharging fresh blood stool, cellulitis, hemorrhoid, rotten skin ulcer.Pudendum is itched bitterly, soup, burning hot wound；The Radix Astragali: medicinal part is the dry root of leguminous plant Radix Astagali or Radix Astragali.Sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and bursts for a long time and does not hold back, and blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst, chronic nephritis proteinuria, diabetes；Halloysitum Rubrum: for silicates mineral halloysites race halloysite, main containing four water aluminium silicate.Sweet in the mouth, acid, puckery, warm in nature.Return large intestine, stomach warp.Astringing intestine to stop diarrhea, hemostasis, promoting tissue regeneration and ulcer healing.For chronic diarrhea chronic dysentery, fecal blood, bleeding not during menses；External treatment skin infection is burst for a long time and is not held back, and eczema pus is contaminated；Mel: the honey that this product is Apidae insecticide apis cerana or apis mellifera Linnaeus is made.Sweet, flat.Return lung, spleen, large intestine channel.Invigorating middle warmer, moisturizes, pain relieving, removing toxic substances.For gastral cavity abdomen void pain, dryness of the lung dry cough, dryness of the intestine constipation；External treatment skin infection is not held back, burn due to hot liquid or fire.
Self-biting disease is a kind of common chronic disease of mink, and disease is characterized by that suffering from ermine presents periodicity excitement, and bite autologous certain position.The lighter bites fur, makes hide degradation；Severe one, because of recurrent exerbation, tears muscle secondary infection, often dead because of body constitution exhaustion and septicemia.Main clinical symptoms is disease beast fever, and individual event is turn-taked, and stings a certain position of oneself health or tail biting bar, or stings buttocks, and some cases also sting sole or abdominal tissues, and send ear-piercing shriek.Biting off by hair, destroy the integrity of skin, severe patient bites tail point off, tears muscle, causes docking, blood.Recurrent exerbation, stimulates sensitivity to external world, often because environmental stimuli causes fever to show effect.Sometimes break by the teeth root of the tail, knee joint, sole and abdominal tissues, often cause death because of the infection of severe trauma.Indivedual excitation times also sting cage net.Present invention applicant, by research to cause of disease disease, adopts differential diagnosis in tcm therapy, by tranquillizing and allaying excitement, clearing away heat and cooling blood, disinfection, dispersing the stagnated live-QI to relieve the stagnation of QI, expelling pus and promoting granulation the rule for the treatment of treat Mink Self-Biting Disease.
Fang Zhong, Radix Et Caulis Acanthopanacis Senticosi benefiting vital QI for tranquillizing, promoting blood circulation to remove obstruction in the collateral, Concha Margaritifera suppressing the hyperactive liver, YANG hyperactivity suppressing, calm the nerves, arresting convulsion, hemostasis, Dens Draconis tranquillizing the mind by relieving convulsion, promoting tissue regeneration and ulcer healing, Cornu Naemorhedi is calm, brings down a fever, improving eyesight, hemostasis, this four Chinese medicine share the effect with replenishing QI to invigorate the spleen, tranquillizing and allaying excitement, and the nerve making mink disorderly is inhibited and recovers normal function, block that affected part is neural conducts pessimal stimulation to maincenter, first make mink stop from stinging property from injury behavior, be principal agent altogether；Herba Ludisiae Discoloris cooling blood for hemostasis, nourishing YIN and moistening the lung, Radix Paeoniae Rubra clearing away heat and cooling blood, eliminating stasis to stop pain, Radix Cynanchi Atrati clearing away heat and cooling blood, detoxification sore treatment, Spina Gleditsiae detumescence poison holding, evacuation of pus parasite killing, Folium eucalypti globueli (Eucalyptus globulus Labill.) dispelling wind to relieve the exterior syndrome, heat-clearing and toxic substances removing, killing parasites for relieving itching, play effect of clearing away heat and cooling blood, warming middle-JIAO to relieve pain, disinfection altogether, dispel internal excess-fire, cleanse the heat of internal organs antipruritic, the disinfection that relieves the pain, alleviate the neural pain of affected part and pruritus, block affected part neural to maincenter conduction pessimal stimulation, be ministerial drug altogether；Citrus aurantium L. var. amara Engl. promoting the circulation of QI to alleviate the stagnation in middle-JIAO, Flos Rosae Rugosae promoting QI circulation for relieving depression and blood, pain relieving, Flos Albiziae Shu Yu, regulate the flow of vital energy, calm the nerves, active, nourish blood, YIN nourishing kidney, clear away heart-fire improving eyesight, this four Chinese medicine compatibility has dispersing the stagnated live-QI to relieve the stagnation of QI, the effect calmed the nerves of regulating the flow of vital energy, QI and blood in health is given defeated the letting out of operation come, by correcting internal body of gland abnormal secretion, adjusts smooth temperament and interest, make mink peace and quiet calm the nerves, be adjuvant drug altogether；Cortex sophorae expelling wind and removing dampness, reducing swelling and alleviating pain, Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation, Halloysitum Rubrum hemostasis, promoting tissue regeneration and ulcer healing, Mel invigorating middle warmer is moisturized, analgesic antidotal, antipruritic hemostasis, expelling pus and promoting granulation with treat mink because scabbing from the affected part stinging generation, infecting, the disease such as suppuration, promote fur regeneration, altogether for making medicine.Inventive formulation has been also added with pine needle powder, shrimp meal, Testa oryzae, Pupa bombycis, fish scale, Fructus Canarii albi wet goods composition, wherein, pine needle powder can detoxify parasite killing, eliminate stagnation of QI due to dyspepsia, promote mink restoration ecosystem, strengthen premunition, shrimp meal is added in feedstuff can food calling mink diet, Testa oryzae strengthening the spleen and stomach, swelling diuretic, and containing some unsaturated fatty acids, Pupa bombycis can help digestion and regulate the flow of vital energy, improve feedstuff mouthfeel, promote mink feed, fish scale contains rich in protein, fat and multivitamin, olive oil can improve mink digestive system function, it is beneficial to mink to digest and assimilate, also there is food calling effect.
The preparation method that it is a further object of the present invention to provide a kind of feed additive treating Mink Self-Biting Disease, described preparation method comprises the following steps:
(1) after being burnt by Cornu Naemorhedi, carry out micronizing, obtain Cornu Naemorhedi superfine powder；
(2) being put by Radix Paeoniae Rubra in preheating parch container, heat with slow fire, fry to color burn, taking-up is dried in the air cool, standby；
(3) after Concha Margaritifera, Halloysitum Rubrum coarse pulverization, 0.5h will be heated under high temperature, be then put in quenching in cold water, then be ground pulverizing, cross 80 mesh sieves, obtain admixed finepowder；
(4) after Dens Draconis being cleaned up, it is fired in crucible and is popular in, take out, cool with grinding pulverizing into powder and crossing 80 mesh sieves, standby；
(5) by Radix Et Caulis Acanthopanacis Senticosi, Herba Ludisiae Discoloris, Radix Cynanchi Atrati, Spina Gleditsiae, Folium eucalypti globueli (Eucalyptus globulus Labill.), Citrus aurantium L. var. amara Engl., Flos Rosae Rugosae, Flos Albiziae, Cortex sophorae, the Radix Astragali and step (2) process after Radix Paeoniae Rubra weigh by proportioning and mix after, grind to 80 orders, add step (3), (4) admixed finepowder obtained respectively, Dens Draconis powder mix homogeneously, gross weight is designated as 1 part, add 3 parts of sterilized water, 0.5 part of ethanol, 1h is soaked at 50 ± 5 DEG C, then said medicine and liquid are collectively disposed in microwave extracting tank and extract, control microwave frequency is 1000-1600MHz, microwave power is 80-200W/L, carry out microwave radiation, then the operating pressure in extractor is stepped up to 0.15-0.3MPa in 5-10min, microwave irradiation time amounts to 20-30min；
(6) after the extract of step (3) being decompressed, filter, reclaim ethanol, collect filtrate, by filtrate spray drying, and cross 100 order mesh screens, obtain Chinese medicine extract；
(7) by fish scale clean dry, then fish scale and Pupa bombycis are ground, with pine needle powder, shrimp meal, Testa oryzae, olive oil, Mel, step (6) gained Chinese medicine extract mix, be uniformly mixed, obtain the feed additive of described treatment Mink Self-Biting Disease.
Further, step (3) described microwave frequency is 1400MHz, and microwave power is 150W/L.
Further, the operating pressure in extractor is stepped up to 0.2MPa by step (3) in 5-10min.
Further, the described microwave irradiation time of step (3) amounts to 25min.
Using method: by the feed additive of the present invention with normal feedstuff with 1:(10-20) ratio mix homogeneously after throw something and feed, one day three times；Preferably, throw something and feed after the feed additive of the present invention is mixed homogeneously with the ratio of 1:15 with normal feedstuff, one day three times.
In the preparation method of the present invention, after Concha Margaritifera, Halloysitum Rubrum coarse pulverization, heating under high temperature, be then put in cold water quenching and be ground pulverizing again so that it is can be easier crushed, and grinding particle size is little and uniform, the utilization rate of active components in Ore be high；nullWith without sterilized water after medicine is pulverized、The mixed liquor of ethanol soaks 1h at 50 ± 5 DEG C，Sterilized water can be made、The cell interior that toluene and ethanol molecule crush well into cell wall，Fully infiltrate medical material，Make medical material when microwave extracting，Microwave heating makes solvent sterilized water、Toluene and ethanol absorb microwave energy and produce substantial amounts of thermal energy，Temperature in born of the same parents is made to increase rapidly，Cell membrane and cell wall are broken through by pressure further that produce，Form some small holes，Until there is crackle in cell surface，Solvent is made to enter cell interior more fully，Microwave can also promote that the molecule in solvent quickly rotates and moves，Especially water、These polar molecules of ethanol can produce moment under microwave action to be intensified，Produce the vibration of key、Tear and interparticle friction and collision，And it is quickly generated a large amount of heat energy，Strong in cell interior penetration power，Cell is promoted to continue to break，The effective ingredient in Cell sap and medicine is made quickly to overflow and diffuse in solvent，Substantially reduce the extraction time of effective ingredient，Drastically increase extraction efficiency，And microwave heating is uniform，Belong to intraor extracellular to heat simultaneously，Avoid thermograde during traditional extraction heating，Medical material heated time is short，Be conducive to the extraction of effective ingredient in medical material.Additionally microwave extracting can extract the effective ingredient in medical material in high volume, and solvent load is less than traditional handicraft simultaneously, facilitates in subsequent step and extract concentration is purified, save the time, improves production efficiency.
Beneficial effects of the present invention:
(1) for Mink Self-Biting Disease, have studied a kind of feed additive, this feed additive with the addition of some Chinese medicine ingredients, imparts effect of this feed additive tranquillizing and allaying excitement, clearing away heat and cooling blood, disinfection, dispersing the stagnated live-QI to relieve the stagnation of QI, expelling pus and promoting granulation, can effectively treat Mink Self-Biting Disease.Radix Et Caulis Acanthopanacis Senticosi benefiting vital QI for tranquillizing, promoting blood circulation to remove obstruction in the collateral, Concha Margaritifera suppressing the hyperactive liver, YANG hyperactivity suppressing, calms the nerves, arresting convulsion, hemostasis, Dens Draconis tranquillizing the mind by relieving convulsion, promoting tissue regeneration and ulcer healing, Cornu Naemorhedi is calm, bring down a fever, improving eyesight, hemostasis, this four Chinese medicine share the effect with replenishing QI to invigorate the spleen, tranquillizing and allaying excitement, and the nerve making mink disorderly is inhibited and recovers normal function, blocks affected part neural to maincenter conduction pessimal stimulation, first make mink stop from stinging property from injury behavior, be principal agent altogether；Herba Ludisiae Discoloris cooling blood for hemostasis, nourishing YIN and moistening the lung, Radix Paeoniae Rubra clearing away heat and cooling blood, eliminating stasis to stop pain, Radix Cynanchi Atrati clearing away heat and cooling blood, detoxification sore treatment, Spina Gleditsiae detumescence poison holding, evacuation of pus parasite killing, Folium eucalypti globueli (Eucalyptus globulus Labill.) dispelling wind to relieve the exterior syndrome, heat-clearing and toxic substances removing, killing parasites for relieving itching, play effect of clearing away heat and cooling blood, warming middle-JIAO to relieve pain, disinfection altogether, dispel internal excess-fire, cleanse the heat of internal organs antipruritic, the disinfection that relieves the pain, alleviate the neural pain of affected part and pruritus, block affected part neural to maincenter conduction pessimal stimulation, be ministerial drug altogether；Citrus aurantium L. var. amara Engl. promoting the circulation of QI to alleviate the stagnation in middle-JIAO, Flos Rosae Rugosae promoting QI circulation for relieving depression and blood, pain relieving, Flos Albiziae Shu Yu, regulate the flow of vital energy, calm the nerves, active, nourish blood, YIN nourishing kidney, clear away heart-fire improving eyesight, this four Chinese medicine compatibility has dispersing the stagnated live-QI to relieve the stagnation of QI, the effect calmed the nerves of regulating the flow of vital energy, QI and blood in health is given defeated the letting out of operation come, by correcting internal body of gland abnormal secretion, adjusts smooth temperament and interest, make mink peace and quiet calm the nerves, be adjuvant drug altogether；Cortex sophorae expelling wind and removing dampness, reducing swelling and alleviating pain, Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation, Halloysitum Rubrum hemostasis, promoting tissue regeneration and ulcer healing, Mel invigorating middle warmer is moisturized, analgesic antidotal, antipruritic hemostasis, expelling pus and promoting granulation with treat mink because scabbing from the affected part stinging generation, infecting, the disease such as suppuration, promote fur regeneration, altogether for making medicine.
(2) inventive formulation has been also added with pine needle powder, shrimp meal, Testa oryzae, Pupa bombycis, fish scale, Fructus Canarii albi wet goods composition, wherein, pine needle powder can detoxify parasite killing, eliminate stagnation of QI due to dyspepsia, promote mink restoration ecosystem, strengthen premunition, shrimp meal is added in feedstuff can food calling mink diet, Testa oryzae strengthening the spleen and stomach, swelling diuretic, and containing some unsaturated fatty acids, Pupa bombycis can help digestion and regulate the flow of vital energy, improve feedstuff mouthfeel, promote mink feed, fish scale contains rich in protein, fat and multivitamin, olive oil can improve mink digestive system function, it is beneficial to mink to digest and assimilate, also there is food calling effect.
(3) in the preparation method of the present invention, after Concha Margaritifera, Halloysitum Rubrum coarse pulverization, heat under high temperature, then it is put in cold water quenching and is ground again pulverizing, making it can be easier crushed, and grinding particle size is little and uniform, the utilization rate of active components in Ore be high；nullWith without sterilized water after medicine is pulverized、The mixed liquor of ethanol soaks 1h at 50 ± 5 DEG C，Sterilized water can be made、The cell interior that toluene and ethanol molecule crush well into cell wall，Fully infiltrate medical material，Make medical material when microwave extracting，Microwave heating makes solvent sterilized water、Toluene and ethanol absorb microwave energy and produce substantial amounts of thermal energy，Temperature in born of the same parents is made to increase rapidly，Cell membrane and cell wall are broken through by pressure further that produce，Form some small holes，Until there is crackle in cell surface，Solvent is made to enter cell interior more fully，Microwave can also promote that the molecule in solvent quickly rotates and moves，Especially water、These polar molecules of ethanol can produce moment under microwave action to be intensified，Produce the vibration of key、Tear and interparticle friction and collision，And it is quickly generated a large amount of heat energy，Strong in cell interior penetration power，Cell is promoted to continue to break，The effective ingredient in Cell sap and medicine is made quickly to overflow and diffuse in solvent，Substantially reduce the extraction time of effective ingredient，Drastically increase extraction efficiency，And microwave heating is uniform，Belong to intraor extracellular to heat simultaneously，Avoid thermograde during traditional extraction heating，Medical material heated time is short，Be conducive to the extraction of effective ingredient in medical material.Additionally microwave extracting can extract the effective ingredient in medical material in high volume, and solvent load is less than traditional handicraft simultaneously, facilitates in subsequent step and extract concentration is purified, save the time, improves production efficiency.
(4) each component of the feed additive of the treatment Mink Self-Biting Disease of the present invention is environmental protection raw material, mink is nontoxic, do not contain chemical drugs or antibiotic, mix feeding mink in the normal feedstuff of mink in use, the therapeutic effect of the mink suffering from self-biting disease is good, effective percentage is high, promote the fast quick-recovery of mink, shorten and recover convalescent period, promote the fur regeneration of mink affected part, be conducive to the sustainable health development of mink farming industry, improve the economic benefit of raiser.
Detailed description of the invention
Below in conjunction with embodiments of the invention, technical scheme is clearly and completely described.
Embodiment 1
A kind of feed additive treating Mink Self-Biting Disease, is made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 20 parts, Concha Margaritifera 10 parts, Dens Draconis 9 parts, Cornu Naemorhedi 4 parts, Herba Ludisiae Discoloris 6 parts, Radix Paeoniae Rubra 6 parts, Radix Cynanchi Atrati 10 parts, Spina Gleditsiae 6 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 5 parts, Citrus aurantium L. var. amara Engl. 3 parts, Flos Rosae Rugosae 4 parts, Flos Albiziae 5 parts, Cortex sophorae 8 parts, the Radix Astragali 10 parts, Halloysitum Rubrum 8 parts, Mel 8 parts, pine needle powder 8 parts, shrimp meal 10 parts, 4 parts of Testa oryzae, Pupa bombycis 5 parts, 4 parts of fish scale, 3 parts of olive oil.
The preparation method of the feed additive of described treatment Mink Self-Biting Disease, described preparation method comprises the following steps:
(1) after being burnt by Cornu Naemorhedi, carry out micronizing, obtain Cornu Naemorhedi superfine powder；
(2) being put by Radix Paeoniae Rubra in preheating parch container, heat with slow fire, fry to color burn, taking-up is dried in the air cool, standby；
(3) after Concha Margaritifera, Halloysitum Rubrum coarse pulverization, 0.5h will be heated under high temperature, be then put in quenching in cold water, then be ground pulverizing, cross 80 mesh sieves, obtain admixed finepowder；
(4) after Dens Draconis being cleaned up, it is fired in crucible and is popular in, take out, cool with grinding pulverizing into powder and crossing 80 mesh sieves, standby；
(5) by Radix Et Caulis Acanthopanacis Senticosi, Herba Ludisiae Discoloris, Radix Cynanchi Atrati, Spina Gleditsiae, Folium eucalypti globueli (Eucalyptus globulus Labill.), Citrus aurantium L. var. amara Engl., Flos Rosae Rugosae, Flos Albiziae, Cortex sophorae, the Radix Astragali and step (2) process after Radix Paeoniae Rubra weigh by proportioning and mix after, grind to 80 orders, add step (3), (4) admixed finepowder obtained respectively, Dens Draconis powder mix homogeneously, gross weight is designated as 1 part, add 3 parts of sterilized water, 0.5 part of ethanol, 1h is soaked at 50 ± 5 DEG C, then said medicine and liquid are collectively disposed in microwave extracting tank and extract, control microwave frequency is 1000MHz, microwave power is 80W/L, carry out microwave radiation, then the operating pressure in extractor is stepped up to 0.3MPa in 5-10min, microwave irradiation time amounts to 30min；
(6) after the extract of step (3) being decompressed, filter, reclaim ethanol, collect filtrate, by filtrate spray drying, and cross 100 order mesh screens, obtain Chinese medicine extract；
(7) by fish scale clean dry, then fish scale and Pupa bombycis are ground, with pine needle powder, shrimp meal, Testa oryzae, olive oil, Mel, step (6) gained Chinese medicine extract mix, be uniformly mixed, obtain the feed additive of described treatment Mink Self-Biting Disease.
Embodiment 2
A kind of feed additive treating Mink Self-Biting Disease, is made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 30 parts, Concha Margaritifera 20 parts, Dens Draconis 15 parts, Cornu Naemorhedi 10 parts, Herba Ludisiae Discoloris 10 parts, Radix Paeoniae Rubra 12 parts, Radix Cynanchi Atrati 15 parts, Spina Gleditsiae 10 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 15 parts, Citrus aurantium L. var. amara Engl. 9 parts, Flos Rosae Rugosae 10 parts, Flos Albiziae 10 parts, Cortex sophorae 16 parts, the Radix Astragali 20 parts, Halloysitum Rubrum 12 parts, Mel 16 parts, pine needle powder 12 parts, shrimp meal 20 parts, 10 parts of Testa oryzae, Pupa bombycis 9 parts, 8 parts of fish scale, 7 parts of olive oil.
The preparation method of the feed additive of described treatment Mink Self-Biting Disease, described preparation method comprises the following steps:
(1) after being burnt by Cornu Naemorhedi, carry out micronizing, obtain Cornu Naemorhedi superfine powder；
(2) being put by Radix Paeoniae Rubra in preheating parch container, heat with slow fire, fry to color burn, taking-up is dried in the air cool, standby；
(3) after Concha Margaritifera, Halloysitum Rubrum coarse pulverization, 0.5h will be heated under high temperature, be then put in quenching in cold water, then be ground pulverizing, cross 80 mesh sieves, obtain admixed finepowder；
(4) after Dens Draconis being cleaned up, it is fired in crucible and is popular in, take out, cool with grinding pulverizing into powder and crossing 80 mesh sieves, standby；
(5) by Radix Et Caulis Acanthopanacis Senticosi, Herba Ludisiae Discoloris, Radix Cynanchi Atrati, Spina Gleditsiae, Folium eucalypti globueli (Eucalyptus globulus Labill.), Citrus aurantium L. var. amara Engl., Flos Rosae Rugosae, Flos Albiziae, Cortex sophorae, the Radix Astragali and step (2) process after Radix Paeoniae Rubra weigh by proportioning and mix after, grind to 80 orders, add step (3), (4) admixed finepowder obtained respectively, Dens Draconis powder mix homogeneously, gross weight is designated as 1 part, add 3 parts of sterilized water, 0.5 part of ethanol, 1h is soaked at 50 ± 5 DEG C, then said medicine and liquid are collectively disposed in microwave extracting tank and extract, control microwave frequency is 1600MHz, microwave power is 200W/L, carry out microwave radiation, then the operating pressure in extractor is stepped up to 0.15MPa in 5-10min, microwave irradiation time amounts to 20min；
(6) after the extract of step (3) being decompressed, filter, reclaim ethanol, collect filtrate, by filtrate spray drying, and cross 100 order mesh screens, obtain Chinese medicine extract；
(7) by fish scale clean dry, then fish scale and Pupa bombycis are ground, with pine needle powder, shrimp meal, Testa oryzae, olive oil, Mel, step (6) gained Chinese medicine extract mix, be uniformly mixed, obtain the feed additive of described treatment Mink Self-Biting Disease.
Embodiment 3
A kind of feed additive treating Mink Self-Biting Disease, is made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 25 parts, Concha Margaritifera 15 parts, Dens Draconis 12 parts, Cornu Naemorhedi 7 parts, Herba Ludisiae Discoloris 8 parts, Radix Paeoniae Rubra 9 parts, Radix Cynanchi Atrati 12 parts, Spina Gleditsiae 8 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, Citrus aurantium L. var. amara Engl. 6 parts, Flos Rosae Rugosae 7 parts, Flos Albiziae 8 parts, Cortex sophorae 12 parts, the Radix Astragali 15 parts, Halloysitum Rubrum 10 parts, Mel 12 parts, pine needle powder 10 parts, shrimp meal 15 parts, 7 parts of Testa oryzae, Pupa bombycis 7 parts, 6 parts of fish scale, 5 parts of olive oil.
The preparation method of the feed additive of described treatment Mink Self-Biting Disease, described preparation method comprises the following steps:
(1) after being burnt by Cornu Naemorhedi, carry out micronizing, obtain Cornu Naemorhedi superfine powder；
(2) being put by Radix Paeoniae Rubra in preheating parch container, heat with slow fire, fry to color burn, taking-up is dried in the air cool, standby；
(3) after Concha Margaritifera, Halloysitum Rubrum coarse pulverization, 0.5h will be heated under high temperature, be then put in quenching in cold water, then be ground pulverizing, cross 80 mesh sieves, obtain admixed finepowder；
(4) after Dens Draconis being cleaned up, it is fired in crucible and is popular in, take out, cool with grinding pulverizing into powder and crossing 80 mesh sieves, standby；
(5) by Radix Et Caulis Acanthopanacis Senticosi, Herba Ludisiae Discoloris, Radix Cynanchi Atrati, Spina Gleditsiae, Folium eucalypti globueli (Eucalyptus globulus Labill.), Citrus aurantium L. var. amara Engl., Flos Rosae Rugosae, Flos Albiziae, Cortex sophorae, the Radix Astragali and step (2) process after Radix Paeoniae Rubra weigh by proportioning and mix after, grind to 80 orders, add step (3), (4) admixed finepowder obtained respectively, Dens Draconis powder mix homogeneously, gross weight is designated as 1 part, add 3 parts of sterilized water, 0.5 part of ethanol, 1h is soaked at 50 ± 5 DEG C, then said medicine and liquid are collectively disposed in microwave extracting tank and extract, control microwave frequency is 1300MHz, microwave power is 150W/L, carry out microwave radiation, then the operating pressure in extractor is stepped up to 0.2MPa in 5-10min, microwave irradiation time amounts to 25min；
(6) after the extract of step (3) being decompressed, filter, reclaim ethanol, collect filtrate, by filtrate spray drying, and cross 100 order mesh screens, obtain Chinese medicine extract；
(7) by fish scale clean dry, then fish scale and Pupa bombycis are ground, with pine needle powder, shrimp meal, Testa oryzae, olive oil, Mel, step (6) gained Chinese medicine extract mix, be uniformly mixed, obtain the feed additive of described treatment Mink Self-Biting Disease.
Embodiment 4
A kind of feed additive treating Mink Self-Biting Disease, is made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 30 parts, Concha Margaritifera 10 parts, Dens Draconis 12 parts, Cornu Naemorhedi 4 parts, Herba Ludisiae Discoloris 6 parts, Radix Paeoniae Rubra 9 parts, Radix Cynanchi Atrati 12 parts, Spina Gleditsiae 8 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, Citrus aurantium L. var. amara Engl. 9 parts, Flos Rosae Rugosae 7 parts, Flos Albiziae 8 parts, Cortex sophorae 10 parts, the Radix Astragali 12 parts, Halloysitum Rubrum 8 parts, Mel 8 parts, pine needle powder 8 parts, shrimp meal 15 parts, 7 parts of Testa oryzae, Pupa bombycis 7 parts, 6 parts of fish scale, 5 parts of olive oil.
The preparation method of the feed additive of described treatment Mink Self-Biting Disease, described preparation method comprises the following steps:
(1) after being burnt by Cornu Naemorhedi, carry out micronizing, obtain Cornu Naemorhedi superfine powder；
(2) being put by Radix Paeoniae Rubra in preheating parch container, heat with slow fire, fry to color burn, taking-up is dried in the air cool, standby；
(3) after Concha Margaritifera, Halloysitum Rubrum coarse pulverization, 0.5h will be heated under high temperature, be then put in quenching in cold water, then be ground pulverizing, cross 80 mesh sieves, obtain admixed finepowder；
(4) after Dens Draconis being cleaned up, it is fired in crucible and is popular in, take out, cool with grinding pulverizing into powder and crossing 80 mesh sieves, standby；
(5) by Radix Et Caulis Acanthopanacis Senticosi, Herba Ludisiae Discoloris, Radix Cynanchi Atrati, Spina Gleditsiae, Folium eucalypti globueli (Eucalyptus globulus Labill.), Citrus aurantium L. var. amara Engl., Flos Rosae Rugosae, Flos Albiziae, Cortex sophorae, the Radix Astragali and step (2) process after Radix Paeoniae Rubra weigh by proportioning and mix after, grind to 80 orders, add step (3), (4) admixed finepowder obtained respectively, Dens Draconis powder mix homogeneously, gross weight is designated as 1 part, add 3 parts of sterilized water, 0.5 part of ethanol, 1h is soaked at 50 ± 5 DEG C, then said medicine and liquid are collectively disposed in microwave extracting tank and extract, control microwave frequency is 1400MHz, microwave power is 120W/L, carry out microwave radiation, then the operating pressure in extractor is stepped up to 0.23MPa in 5-10min, microwave irradiation time amounts to 25min；
(6) after the extract of step (3) being decompressed, filter, reclaim ethanol, collect filtrate, by filtrate spray drying, and cross 100 order mesh screens, obtain Chinese medicine extract；
(7) by fish scale clean dry, then fish scale and Pupa bombycis are ground, with pine needle powder, shrimp meal, Testa oryzae, olive oil, Mel, step (6) gained Chinese medicine extract mix, be uniformly mixed, obtain the feed additive of described treatment Mink Self-Biting Disease.
Feed additive effect test of the present invention
Contrast experiment 1
Test site is selected in mink farming field, Qingdao, in order to verify the therapeutic effect of the present invention, the mink suffering from self-biting disease is tested, and test water ermine extent is basically identical, and the state of an illness is: fever, individual event is turn-taked, sting a certain position of oneself health or tail biting bar, or sting buttocks, what have also stings sole or abdominal tissues, and sends ear-piercing shriek.Biting off by hair, destroy the integrity of skin, severe patient bites tail point off, tears muscle, causes docking, blood.Recurrent exerbation, stimulates sensitivity to external world, often because environmental stimuli causes fever to show effect.Sometimes break by the teeth root of the tail, knee joint, sole and abdominal tissues, often cause death because of the infection of severe trauma.
Being divided into 6 groups, often group 20, often group processes as follows:
Matched group: use chlorpromazine hydrochloride 13g, breast strong calcium 0.25g, compound vitamin B 0.05g, be mixed in normal feedstuff after grinding mixing and feed, every day three times, until mink recovery from illness.
Experiment A group: Chinese medicine preparation prepared by the embodiment of the present invention 1 is ground into after powder is mixed homogeneously with the ratio of 1:20 with normal feedstuff and throws something and feeds, every day three times, until mink recovery from illness.
Experiment B group: Chinese medicine preparation prepared by the embodiment of the present invention 2 is ground into after powder is mixed homogeneously with the ratio of 1:10 with normal feedstuff and throws something and feeds, every day three times, until mink recovery from illness.
Experiment C group: Chinese medicine preparation prepared by the embodiment of the present invention 3 is ground into after powder is mixed homogeneously with the ratio of 1:15 with normal feedstuff and throws something and feeds, every day three times, until mink recovery from illness.
Experiment D group: Chinese medicine preparation prepared by the embodiment of the present invention 4 is ground into after powder is mixed homogeneously with the ratio of 1:13 with normal feedstuff and throws something and feeds, every day three times, until mink recovery from illness.
Experimental result is in Table 1:
The feed additive of table 1 present invention therapeutic effect to Mink Self-Biting Disease
Test result indicate that: self-biting disease is had significant therapeutic effect by the feed additive of the treatment Mink Self-Biting Disease of the present invention, when using the feed additive treatment Mink Self-Biting Disease of the present invention, mink Health restoration speed is fast, 2 days minks of medication are namely without from stinging behavior, mental restoration is normal, feeds 5-7 days and can recover, is snapped illing skin quickly-healing, fur regenerates, and its effective percentage is up to more than 95%.
The above is the preferred embodiment of the present invention; its object is to allow person skilled in the art understand present invention and to be carried out; should be understood that; for those skilled in the art; under the premise without departing from the principles of the invention; can also making some improvements and modifications, these improvements and modifications are also considered as protection scope of the present invention.
Claims (8)
1. the feed additive treating Mink Self-Biting Disease, it is characterized in that, it is made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 20-30 part, Concha Margaritifera 10-20 part, Dens Draconis 9-15 part, Cornu Naemorhedi 4-10 part, Herba Ludisiae Discoloris 6-10 part, Radix Paeoniae Rubra 6-12 part, Radix Cynanchi Atrati 10-15 part, Spina Gleditsiae 6-10 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 5-15 part, Citrus aurantium L. var. amara Engl. 3-9 part, Flos Rosae Rugosae 4-10 part, Flos Albiziae 5-10 part, Cortex sophorae 8-16 part, Radix Astragali 10-20 part, Halloysitum Rubrum 8-12 part, Mel 8-16 part, pine needle powder 8-12 part, shrimp meal 10-20 part, Testa oryzae 4-10 part, Pupa bombycis 5-9 part, fish scale 4-8 part, olive oil 3-7 part.
2. a kind of feed additive treating Mink Self-Biting Disease as claimed in claim 1, it is characterized in that, be made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 20 parts, Concha Margaritifera 10 parts, Dens Draconis 9 parts, Cornu Naemorhedi 4 parts, Herba Ludisiae Discoloris 6 parts, Radix Paeoniae Rubra 6 parts, Radix Cynanchi Atrati 10 parts, Spina Gleditsiae 6 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 5 parts, Citrus aurantium L. var. amara Engl. 3 parts, Flos Rosae Rugosae 4 parts, Flos Albiziae 5 parts, Cortex sophorae 8 parts, the Radix Astragali 10 parts, Halloysitum Rubrum 8 parts, Mel 8 parts, pine needle powder 8 parts, shrimp meal 10 parts, 4 parts of Testa oryzae, Pupa bombycis 5 parts, 4 parts of fish scale, 3 parts of olive oil.
3. a kind of feed additive treating Mink Self-Biting Disease as claimed in claim 1, it is characterized in that, be made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 30 parts, Concha Margaritifera 20 parts, Dens Draconis 15 parts, Cornu Naemorhedi 10 parts, Herba Ludisiae Discoloris 10 parts, Radix Paeoniae Rubra 12 parts, Radix Cynanchi Atrati 15 parts, Spina Gleditsiae 10 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 15 parts, Citrus aurantium L. var. amara Engl. 9 parts, Flos Rosae Rugosae 10 parts, Flos Albiziae 10 parts, Cortex sophorae 16 parts, the Radix Astragali 20 parts, Halloysitum Rubrum 12 parts, Mel 16 parts, pine needle powder 12 parts, shrimp meal 20 parts, 10 parts of Testa oryzae, Pupa bombycis 9 parts, 8 parts of fish scale, 7 parts of olive oil.
4. a kind of feed additive treating Mink Self-Biting Disease as claimed in claim 1, it is characterized in that, be made up of each component of following parts by weight: Radix Et Caulis Acanthopanacis Senticosi 25 parts, Concha Margaritifera 15 parts, Dens Draconis 12 parts, Cornu Naemorhedi 7 parts, Herba Ludisiae Discoloris 8 parts, Radix Paeoniae Rubra 9 parts, Radix Cynanchi Atrati 12 parts, Spina Gleditsiae 8 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, Citrus aurantium L. var. amara Engl. 6 parts, Flos Rosae Rugosae 7 parts, Flos Albiziae 8 parts, Cortex sophorae 12 parts, the Radix Astragali 15 parts, Halloysitum Rubrum 10 parts, Mel 12 parts, pine needle powder 10 parts, shrimp meal 15 parts, 7 parts of Testa oryzae, Pupa bombycis 7 parts, 6 parts of fish scale, 5 parts of olive oil.
5. the preparation method of the feed additive of the treatment Mink Self-Biting Disease that a kind is treated described in any one of claim 1-4, it is characterised in that comprise the following steps:
(1) after being burnt by Cornu Naemorhedi, carry out micronizing, obtain Cornu Naemorhedi superfine powder；
(2) being put by Radix Paeoniae Rubra in preheating parch container, heat with slow fire, fry to color burn, taking-up is dried in the air cool, standby；
(3) after Concha Margaritifera, Halloysitum Rubrum coarse pulverization, 0.5h will be heated under high temperature, be then put in quenching in cold water, then be ground pulverizing, cross 80 mesh sieves, obtain admixed finepowder；
(4) after Dens Draconis being cleaned up, it is fired in crucible and is popular in, take out, cool with grinding pulverizing into powder and crossing 80 mesh sieves, standby；
(5) by Radix Et Caulis Acanthopanacis Senticosi, Herba Ludisiae Discoloris, Radix Cynanchi Atrati, Spina Gleditsiae, Folium eucalypti globueli (Eucalyptus globulus Labill.), Citrus aurantium L. var. amara Engl., Flos Rosae Rugosae, Flos Albiziae, Cortex sophorae, the Radix Astragali and step (2) process after Radix Paeoniae Rubra weigh by proportioning and mix after, grind to 80 orders, add step (3), (4) admixed finepowder obtained respectively, Dens Draconis powder mix homogeneously, gross weight is designated as 1 part, add 3 parts of sterilized water, 0.5 part of ethanol, 1h is soaked at 50 ± 5 DEG C, then said medicine and liquid are collectively disposed in microwave extracting tank and extract, control microwave frequency is 1000-1600MHz, microwave power is 80-200W/L, carry out microwave radiation, then the operating pressure in extractor is stepped up to 0.15-0.3MPa in 5-10min, microwave irradiation time amounts to 20-30min；
(6) after the extract of step (3) being decompressed, filter, reclaim ethanol, collect filtrate, by filtrate spray drying, and cross 100 order mesh screens, obtain Chinese medicine extract；
(7) by fish scale clean dry, then fish scale and Pupa bombycis are ground, with pine needle powder, shrimp meal, Testa oryzae, olive oil, Mel, step (1) prepare Cornu Naemorhedi superfine powder, step (6) gained Chinese medicine extract mix, it is uniformly mixed, obtains the feed additive of described treatment Mink Self-Biting Disease.
6. the preparation method of a kind of feed additive treating Mink Self-Biting Disease as claimed in claim 5, it is characterised in that step (5) described microwave frequency is 1400MHz, and microwave power is 150W/L.
7. the preparation method of a kind of feed additive treating Mink Self-Biting Disease as claimed in claim 5, it is characterised in that the operating pressure in extractor is stepped up to 0.2MPa in (5) by step in 5-10min.
8. the preparation method of a kind of feed additive treating Mink Self-Biting Disease as claimed in claim 5, it is characterised in that the described microwave irradiation time of step (5) amounts to 25min.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106721372A (en) * | 2016-12-07 | 2017-05-31 | 郑州仁宏医药科技有限公司 | It is a kind of to prevent feed medicament of beaver rabbit clostridium welchii disease and preparation method thereof |
| CN107034274A (en) * | 2017-04-13 | 2017-08-11 | 中国农业科学院特产研究所 | A kind of mink stings behavior diagnostic gene and its diagnostic method certainly |
| CN112602835A (en) * | 2020-12-08 | 2021-04-06 | 衡阳师范学院 | Feed additive for improving beef cattle fattening performance, preparation and use method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800376A (en) * | 2014-01-26 | 2015-07-29 | 天津嘉创生物科技有限公司 | Traditional Chinese medicinal oral liquid for treating mink self-biting disease and preparation method thereof |
-
2016
- 2016-04-29 CN CN201610280844.5A patent/CN105796974A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800376A (en) * | 2014-01-26 | 2015-07-29 | 天津嘉创生物科技有限公司 | Traditional Chinese medicinal oral liquid for treating mink self-biting disease and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106721372A (en) * | 2016-12-07 | 2017-05-31 | 郑州仁宏医药科技有限公司 | It is a kind of to prevent feed medicament of beaver rabbit clostridium welchii disease and preparation method thereof |
| CN107034274A (en) * | 2017-04-13 | 2017-08-11 | 中国农业科学院特产研究所 | A kind of mink stings behavior diagnostic gene and its diagnostic method certainly |
| CN107034274B (en) * | 2017-04-13 | 2020-12-29 | 中国农业科学院特产研究所 | Gene for diagnosing self-biting behavior of mink and diagnosis method thereof |
| CN112602835A (en) * | 2020-12-08 | 2021-04-06 | 衡阳师范学院 | Feed additive for improving beef cattle fattening performance, preparation and use method thereof |
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Application publication date: 20160727 |