CN106266789A - Slimming medicine for external use and preparation method thereof - Google Patents

Slimming medicine for external use and preparation method thereof Download PDF

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Publication number
CN106266789A
CN106266789A CN201610864690.4A CN201610864690A CN106266789A CN 106266789 A CN106266789 A CN 106266789A CN 201610864690 A CN201610864690 A CN 201610864690A CN 106266789 A CN106266789 A CN 106266789A
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weight portion
weight
raw material
external use
material components
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叶秋晗
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Guangzhou Kang Qimei Biotechnology Industry Ltd
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Guangzhou Kang Qimei Biotechnology Industry Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535—Perilla (beefsteak plant)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964—Anemarrhena
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/8994—Coix (Job's tears)
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Abstract

The present invention relates to a kind of slimming medicine for external use and preparation method thereof, raw material components by weight, including Radix Et Rhizoma Rhei 30 70 weight portion, Folium Perillae 20 30 weight portion, Flos Carthami 15 35 weight portion, Fructus Crataegi 20 40 weight portion, Semen Cassiae 10 20 weight portion, Herba Apocyni veneti 30 50 weight portion, the Rhizoma Anemarrhenae 20 35 weight portion, mentha leave 10 30 weight portion, Semen Coicis 15 35 weight portion, Flos Lonicerae 15 25 weight portion, Pericarpium Citri Reticulatae 5 10 weight portion, lemon grass (Cymbopogon citratus) 25 40 weight portion.Preparation method: carry out extracting standby by Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave supercritical fluid；Raw material components in addition to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave is shredded, after vacuum drying, product is mixed by the weight ratio of 8:2 with extraction quintessence oil.The slimming medicine for external use that the present invention provides, pass through hot compress, the efficacy of a drug is allowed to enter human body from SHENJUE acupoint, act on the waist and belly of noxious dampness fat alluvial, toxin expelling desilting, naturally weight reducing, easy to use, effect rapidly, without bounce-back and have no side effect, avoid the infringement to human stomach's function that oral drugs bring simultaneously.

Description

Slimming medicine for external use and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of slimming medicine for external use and preparation method thereof.
Background technology
In recent years, along with growth in the living standard, the nutriture of people is improved, and " person of putting on weight " day by day increases；With This along with the female consumer endless pursuit to slender and graceful in stature, loses weight and is increasingly becoming whole people's behavior simultaneously；Because obesity is not only Affect the work of people, life, attractive in appearance, and drastically influence the healthy of people.
For this demand of consumer, the various fat-reducing modes on market are applied and are given birth to: eat appetrol, perform an operation, joint Food.In appetrol, a large amount of illegal drugs added drastically influence the healthy of people, targeting while poor stability Differing from, easily rebound, fat-reducing effect is unsatisfactory；And operative therapy price is high and to risk height, is unfavorable for that health is good for Health；Bantingism makes people can not obtain the nutrient substance needed for health in time, and the cost of fat-reducing damages health in time.Therefore, Need the banting of a kind of safe without toxic side effect badly, to solve consumer demand.
Summary of the invention
For defect of the prior art, the invention provides a kind of slimming medicine for external use and preparation method thereof, use External application is lost weight, toxin expelling desilting, naturally weight reducing, easy to use, effect rapidly, without rebounding and having no side effect, avoid mouth simultaneously The infringement to human intestines and stomach's function that thing of taking medicine brings.
For achieving the above object, the present invention provides the techniques below scheme to be:
First aspect, the present invention provides a kind of slimming medicine for external use, raw material components by weight, including Radix Et Rhizoma Rhei 30- 70 weight portions, Folium Perillae 20-30 weight portion, Flos Carthami 15-35 weight portion, Fructus Crataegi 30-60 weight portion, Semen Cassiae 10-20 weight portion, sieve Cloth fiber crops 30-50 weight portion, Rhizoma Anemarrhenae 20-35 weight portion, mentha leave 10-30 weight portion, Semen Coicis 15-35 weight portion, Flos Lonicerae 20-35 Weight portion, Pericarpium Citri Reticulatae 5-10 weight portion and lemon grass (Cymbopogon citratus) 25-40 weight portion.
Radix Et Rhizoma Rhei is bitter, cold, has effects such as attacking stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances；It is used for excess-heat just Stomachache secret, stagnant, dysentery are not well, jaundice due to damp-heat.Folium Perillae has effect of relieving exterior syndrome and dispelling cold, relieving QI stagnancy in the stomach；Its diaphoresis power is relatively strong, available In wind and cold table disease, see aversion to cold, heating, the disease such as lossless.Flos Carthami is pungent, warm, has promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contribute to controlling through Close, the side of body twinge of the stagnant stomachache of dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stasis of blood, breast, traumatic injury, skin infection swell and ache curative effect.Fructus Crataegi has fall Blood fat, blood pressure, heart tonifying, arrhythmia etc. act on, and are also the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting, to breast simultaneously The diseases such as diaphragm spleen is full, hernia, blood stasis, amenorrhea have good curative effect；It improves pepsin activity, promotes the digestion of protein；Mountain Short, bristly hair or beard sour in the mouth can stimulate gastric mucosa to promote gastric secretion；Lipase in Fructus Crataegi can promote the digestion of fat；And Fructus Crataegi is to gastrointestinal fortune Dynamic function has regulation effect, and the gastrointestinal smooth muscle of spasticity is had inhibitory action, and the smooth muscle of relaxed state is had excitement Effect.Semen Cassiae contains multivitamin and abundant aminoacid, fat, carbohydrate etc.；It has clearing away liver-fire, dispels the wind The effects such as wet, tonifying kidney and improving eyesight, can make that blood pressure is normal, free movement of the bowels, old eye are not spent, and can be treated constipation due to dry stool, help smoothly Defecation.Herba Apocyni veneti property sweetness and bitterness, cool, relieve inflammation or internal heat, blood pressure lowering, heart tonifying, the effect of diuresis；Cure mainly suppressing the hyperactive liver to calm the nerves, clearing away heat and promoting diuresis, for liver-yang Dizziness, palpitation and insomnia, edema oliguria；Hypertension, neurasthenia, nephritis edema.The Rhizoma Anemarrhenae is bitter, cold；There is clearing away heat-fire, grow Effect that the moon is moisturized；Curing mainly calentura excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat quenches one's thirst, dryness of the intestine constipation；The Rhizoma Anemarrhenae can excess-heat clearly, Again can reducing the asthenic fever.Mentha leave can dispel the wind with stomach invigorating, eliminates the phlegm, function of gallbladder promoting, spasmolytic, improves cat fever, throat, swells and ache, and eliminates Have a headache, have a toothache, feel sick and feel；Can be used in the medicine of anti-inflammation detumescence.Semen Coicis, property slightly sweet flavor is slightly cold, and has inducing diuresis to remove edema, spleen invigorating to go The effects such as wet, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus.Flos Lonicerae, has heat-clearing and toxic substances removing, loosening bowel to relieve constipation, effect of slight of stature abdomen.Pericarpium Citri Reticulatae acrid in the mouth and Micro-hardship, temperature, enter spleen, lung meridian；In reasonable controlled atmosphere, drying dampness to eliminate phlegm effect, can be used for treating stagnation of QI in spleen and stomach, distension and fullness in the abdomen, big constipation Knot.Lemon grass (Cymbopogon citratus) has stomach invigorating, diuresis, prevents anemia and skin care, spleen-and-stomach-invigorating, the effect dispelling flatulence, help digest；Its Glycerin contributes to women skin maintenance and is used；And it contains substantial amounts of vitamin C, it it is the good merchantable brand of cosmetology；Can regulation Fat secretion, blood circulation promoting.Use Radix Et Rhizoma Rhei 30-70 weight portion, Folium Perillae 20-30 weight portion, Flos Carthami 15-35 weight portion, mountain Short, bristly hair or beard 30-60 weight portion, Semen Cassiae 10-20 weight portion, Herba Apocyni veneti 30-50 weight portion, Rhizoma Anemarrhenae 20-35 weight portion, mentha leave 10-30 Weight portion, Semen Coicis 15-35 weight portion, Flos Lonicerae 20-35 weight portion, Pericarpium Citri Reticulatae 5-10 weight portion and lemon grass (Cymbopogon citratus) 25-40 weight portion The slimming medicine for external use prepared for raw material, selects the valuable ingredient of Chinese medicine containing active skull cap components, prescription proportioning science, does not adds Add any Western medicine hormonal components, safe without toxic side effect, have well combustion fat blood fat reducing, relieve inflammation or internal heat, effect of relieving constipation；By its hot compress When SHENJUE acupoint, after it penetrates skin, act on the drug receptor of the fat cell surfaces of local, play the slimming exercise of medicine Effect；Then medicine entrance blood circulation, thus stimulating Qi of meridian, qualcomm meridian, promote QI-blood circulation, improve enterokinesia dynamics, increase The excretion of lipid matter, reaches effect of fat-reducing combustion fat eliminating that defecation is smooth, while abdominal distention.The weight reducing that the present invention provides subtracts Fertile medicine for external use is without oral, thus avoids the infringement to human intestines and stomach's function of the conventional oral appetrol；It passes through external application Reach the purpose of Weight-reducing and lipid-lowering, the intestines and stomach will not be caused stimulation and burden.
It is to say, the slimming medicine for external use that the present invention provides, use external application fat-reducing, by hot compress, allow the efficacy of a drug from god Cave of fainting enters human body, acts on the waist and belly of noxious dampness fat alluvial, toxin expelling desilting, naturally weight reducing, easy to use, effect is rapid, Without rebounding and having no side effect, avoid the infringement to human stomach's function that oral drugs bring simultaneously.
In the further embodiment of the present invention, also include: Herba Pogostemonis 5-10 weight portion, Radix Bupleuri 8-15 weight portion and reed Luxuriant growth 15-30 weight portion.
In the further embodiment of the present invention, it is made up of following raw material components: Radix Et Rhizoma Rhei 40-65 weight portion, Folium Perillae 23- 29 weight portions, Flos Carthami 19-30 weight portion, Fructus Crataegi 35-58 weight portion, Semen Cassiae 13-18 weight portion, Herba Apocyni veneti 33-45 weight portion, Rhizoma Anemarrhenae 25-30 weight portion, mentha leave 15-25 weight portion, Semen Coicis 20-30 weight portion, Flos Lonicerae 23-30 weight portion, Pericarpium Citri Reticulatae 6-9 weight Amount part, lemon grass (Cymbopogon citratus) 29-38 weight portion, Herba Pogostemonis 7-9 weight portion, Radix Bupleuri 10-13 weight portion and Aloe 18-25 weight portion.
In the further embodiment of the present invention, it is made up of following raw material components: Radix Et Rhizoma Rhei 55 weight portion, Folium Perillae 27 weight Part, Flos Carthami 23 weight portion, Fructus Crataegi 45 weight portion, Semen Cassiae 15 weight portion, Herba Apocyni veneti 39 weight portion, the Rhizoma Anemarrhenae 29 weight portion, Herba Menthae Leaf 18 weight portion, Semen Coicis 25 weight portion, Flos Lonicerae 27 weight portion, Pericarpium Citri Reticulatae 9 weight portion, lemon grass (Cymbopogon citratus) 35 weight portion, Herba Pogostemonis 8 weight Part, Radix Bupleuri 12 weight portion and Aloe 23 weight portion.
In the further embodiment of the present invention, it is made up of following raw material components: Radix Et Rhizoma Rhei 43 weight portion, Folium Perillae 23 weight Part, Flos Carthami 29 weight portion, Fructus Crataegi 37 weight portion, Semen Cassiae 17 weight portion Herba Apocyni veneti 40 weight portion, the Rhizoma Anemarrhenae 30 weight portion, mentha leave 25 weight portions, Semen Coicis 23 weight portion, Flos Lonicerae 28 weight portion, Pericarpium Citri Reticulatae 7 weight portion, lemon grass (Cymbopogon citratus) 35 weight portion, Herba Pogostemonis 9 weight portion, Radix Bupleuri 10 weight portion and Aloe 25 weight portion.
Second aspect, the present invention provides the preparation method of a kind of slimming medicine for external use, comprises the following steps: by each raw material Component cleans, dry rear cutout is broken to 3-30 mesh；Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave supercritical by chopping to 3-30 mesh Fluid extracts；Wherein, the temperature of extraction is 43 DEG C-47 DEG C, and pressure is 13.50MPa-18.50MPa, and the time of extraction is 2h-3h；It is centrifuged separating under conditions of rotating speed is 2500-3800r/min by the product after extraction, takes supernatant；Wherein, The time of centrifugation is 5min-10min；By the chopping in addition to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave to 3-30 purpose other Raw material components is heated to reflux 2.5h-4.5h after mixing by the weight ratio of 1:3-1:5 with ethyl acetate under conditions of 58 DEG C-68 DEG C Rear filtration, takes filtrate；Being 0.1Pa-0.08Pa in vacuum after being mixed with filtrate by supernatant, temperature is the bar of 65 DEG C-75 DEG C 100min-200min it is dried under part；Product after dry 100min-200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Each raw material components is cleaned, dries rear cutout and be broken to 3-30 mesh, because active component is extracted in each raw material components Ratio and the degree of grinding of effective percentage and each raw material components there is the biggest relation, by each raw material components to 3-30 mesh, permissible The many active component in each raw material components is leached of most effective and most probable.Using supercritical fluid is 43 DEG C-47 in temperature DEG C, pressure is 13.50MPa-18.50MPa and extraction time is to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and Herba Menthae under conditions of 2h-3h Effective ingredient in leaf extracts, and in each raw material components, active ingredient has special dissolution in supercritical fluid, Under selected parameter, each raw material components is effectively extracted, i.e. can be to greatest extent by each raw material components under low temperature state In active substance propose, and the activity of each active substance will not be destroyed；Applicant finds through great many of experiments: be 43 in temperature DEG C-47 DEG C, pressure 13.50MPa-18.50MPa and extraction time are to utilize supercritical extraction technique pair under conditions of 2h-3h The Pericarpium Citri Reticulatae of the present invention, Flos Carthami, Herba Apocyni veneti and mentha leave extract, and can make the slimming medicine action effect finally prepared More preferably, can more effectively penetrate into skin and play effect of combustion fat blood fat reducing.Product after extracting is 2500-at rotating speed The centrifugation of 5min-10min, the active substance that will extract under high-speed separation state is carried out under conditions of 3800r/min Separate with other impurity components, thus obtain rich in the supernatant of effective ingredient in Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave；Will Chopping in addition to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave presses 1:3-1:5's to other raw material components of 3-30 purpose and ethyl acetate Filter after being heated to reflux 2.5h-4.5h under conditions of 58 DEG C-68 DEG C after weight ratio mixing, take filtrate；Use ethyl acetate pair Chopping to other raw material components of 3-30 purpose in addition to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave carry out the extraction of effective ingredient, have Imitate constituents extraction rate height and the performance of each effective ingredient can be kept to greatest extent；Applicant finds through great many of experiments: will Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave carry out supercritical fluid extraction；By its in addition to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave He carries out ethyl acetate extraction by raw material components, the drug effect of slimming medicine for external use finally prepared can be made more preferable, permeate skin Skin after-burning fat fat reducing effect is higher, and the speed of action during use is faster and without any side effects to human body.By supernatant Being 0.1Pa-0.08Pa in vacuum after mixing with filtrate, temperature is dried 100min-200min under conditions of being 65 DEG C-75 DEG C； Pressure under vacuum condition is consistently lower than atmospheric pressure, and gas molecula number is few, and density is low, and oxygen content is low, so that dry During dry, the working substance mass-energy in each extract preferably keeps primary characteristic；And, its homogeneous heating, from inside to outside to respectively Active substance in extract heats simultaneously, and the internal-external temperature difference of each active substance is the least, will not produce in conventional heating The situation that existing interior external heat is inconsistent, thus do not interfere with the drug effect of the slimming medicine for external use prepared；In vacuum it is 0.1Pa-0.08Pa, temperature is dried 100min-200min under conditions of being 65 DEG C-75 DEG C, can make in supernatant and filtrate Active substance is the driest, and makes best its original character of holding of each active substance.By the product after dry 100min-200min Thing is mixed by the weight ratio of 8:2 with extraction quintessence oil；According to the weight ratio of 8:2, dried product is mixed with extraction quintessence oil, can The permeability of the slimming medicine for external use of the present invention is strengthened while effective ingredient activity in not affecting each raw material components, from And it is more conducive to skin absorption so that the slimming medicine for external use of the present invention, when hot compress is on skin, after it penetrates skin, more Quickly permeate in fat cell surfaces, play the effect of weight reducing of medicine；Then medicine enter blood circulation, be transported to away to The adipose cell at medicine position, thus reach the effect of fat-reducing.
In the further embodiment of the present invention, described supercritical fluid is CO2。
In the further embodiment of the present invention, the temperature of extraction is 46 DEG C, and pressure is 15.45MPa；It is heated to reflux Temperature is 63 DEG C, and the time being heated to reflux is 3.5h.
In the further embodiment of the present invention, each raw material components is shredded to 20 mesh.
Accompanying drawing explanation
Fig. 1 is the flow chart of the preparation method of the slimming medicine for external use in the embodiment of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing, the embodiment of technical solution of the present invention is described in detail.Following example are only used for Technical scheme is more clearly described, is therefore only used as example, and the protection model of the present invention can not be limited with this Enclose.
The present invention provides a kind of slimming medicine for external use, raw material components by weight, including: Radix Et Rhizoma Rhei 30-70 weight portion, Folium Perillae 20-30 weight portion, Flos Carthami 15-35 weight portion, Fructus Crataegi 30-60 weight portion, Semen Cassiae 10-20 weight portion, Herba Apocyni veneti 30-50 Weight portion, Rhizoma Anemarrhenae 20-35 weight portion, mentha leave 10-30 weight portion, Semen Coicis 15-35 weight portion, Flos Lonicerae 20-35 weight portion, old Skin 5-10 weight portion and lemon grass (Cymbopogon citratus) 25-40 weight portion.
Radix Et Rhizoma Rhei is bitter, cold, has effects such as attacking stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances；It is used for excess-heat just Stomachache secret, stagnant, dysentery are not well, jaundice due to damp-heat.Folium Perillae has effect of relieving exterior syndrome and dispelling cold, relieving QI stagnancy in the stomach；Its diaphoresis power is relatively strong, available In wind and cold table disease, see aversion to cold, heating, the disease such as lossless.Flos Carthami is pungent, warm, has promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contribute to controlling through Close, the side of body twinge of the stagnant stomachache of dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stasis of blood, breast, traumatic injury, skin infection swell and ache curative effect.Fructus Crataegi has fall Blood fat, blood pressure, heart tonifying, arrhythmia etc. act on, and are also the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting, to breast simultaneously The diseases such as diaphragm spleen is full, hernia, blood stasis, amenorrhea have good curative effect；It improves pepsin activity, promotes the digestion of protein；Mountain Short, bristly hair or beard sour in the mouth can stimulate gastric mucosa to promote gastric secretion；Lipase in Fructus Crataegi can promote the digestion of fat；And Fructus Crataegi is to gastrointestinal fortune Dynamic function has regulation effect, and the gastrointestinal smooth muscle of spasticity is had inhibitory action, and the smooth muscle of relaxed state is had excitement Effect.Semen Cassiae contains multivitamin and abundant aminoacid, fat, carbohydrate etc.；It has clearing away liver-fire, dispels the wind The effects such as wet, tonifying kidney and improving eyesight, can make that blood pressure is normal, free movement of the bowels, old eye are not spent, and can be treated constipation due to dry stool, help smoothly Defecation.Herba Apocyni veneti property sweetness and bitterness, cool, relieve inflammation or internal heat, blood pressure lowering, heart tonifying, the effect of diuresis；Cure mainly suppressing the hyperactive liver to calm the nerves, clearing away heat and promoting diuresis, for liver-yang Dizziness, palpitation and insomnia, edema oliguria；Hypertension, neurasthenia, nephritis edema.The Rhizoma Anemarrhenae is bitter, cold；There is clearing away heat-fire, grow Effect that the moon is moisturized；Curing mainly calentura excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat quenches one's thirst, dryness of the intestine constipation；The Rhizoma Anemarrhenae can excess-heat clearly, Again can reducing the asthenic fever.Mentha leave can dispel the wind with stomach invigorating, eliminates the phlegm, function of gallbladder promoting, spasmolytic, improves cat fever, throat, swells and ache, and eliminates Have a headache, have a toothache, feel sick and feel；Can be used in the medicine of anti-inflammation detumescence.Semen Coicis, property slightly sweet flavor is slightly cold, and has inducing diuresis to remove edema, spleen invigorating to go The effects such as wet, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus.Flos Lonicerae, has heat-clearing and toxic substances removing, loosening bowel to relieve constipation, effect of slight of stature abdomen.Pericarpium Citri Reticulatae acrid in the mouth and Micro-hardship, temperature, enter spleen, lung meridian；In reasonable controlled atmosphere, drying dampness to eliminate phlegm effect, can be used for treating stagnation of QI in spleen and stomach, distension and fullness in the abdomen, big constipation Knot.Lemon grass (Cymbopogon citratus) has stomach invigorating, diuresis, prevents anemia and skin care, spleen-and-stomach-invigorating, the effect dispelling flatulence, help digest；Its Glycerin contributes to women skin maintenance and is used；And it contains substantial amounts of vitamin C, it it is the good merchantable brand of cosmetology；Can regulation Fat secretion, blood circulation promoting.Use Radix Et Rhizoma Rhei 30-70 weight portion, Folium Perillae 20-30 weight portion, Flos Carthami 15-35 weight portion, mountain Short, bristly hair or beard 30-60 weight portion, Semen Cassiae 10-20 weight portion, Herba Apocyni veneti 30-50 weight portion, Rhizoma Anemarrhenae 20-35 weight portion, mentha leave 10-30 Weight portion, Semen Coicis 15-35 weight portion, Flos Lonicerae 20-35 weight portion, Pericarpium Citri Reticulatae 5-10 weight portion and lemon grass (Cymbopogon citratus) 25-40 weight portion The slimming medicine for external use prepared for raw material, selects the valuable ingredient of Chinese medicine containing active skull cap components, prescription proportioning science, does not adds Add any Western medicine hormonal components, safe without toxic side effect, have well combustion fat blood fat reducing, relieve inflammation or internal heat, effect of relieving constipation；Applied When target fat-reducing position, after it penetrates skin, act on the drug receptor of the fat cell surfaces of local, play subtracting of medicine Fertile effect；Then medicine entrance blood circulation, thus stimulating Qi of meridian, qualcomm meridian, promote QI-blood circulation, improve enterokinesia dynamics, Increase the excretion of lipid matter, reach effect of fat-reducing combustion fat eliminating that defecation is smooth, while abdominal distention.It is thin that the present invention provides Body fat-reducing medicine for external use, without oral, by hot compress, allow the efficacy of a drug enter human body from SHENJUE acupoint, acts on the waist abdomen of noxious dampness fat alluvial Portion, toxin expelling desilting, naturally weight reducing, thus avoid the infringement to human intestines and stomach's function of the conventional oral appetrol；It passes through external application I.e. can reach the purpose of Weight-reducing and lipid-lowering, the intestines and stomach will not be caused stimulation and burden.
Preferably, also include: Herba Pogostemonis 5-10 weight portion, Radix Bupleuri 8-15 weight portion and Aloe 15-30 weight portion.
Herba Pogostemonis property is pungent, tepor, has eliminating turbid pathogen with aromatics and middle preventing or arresting vomiting, delivers the effect of expelling summer-heat；Can be used for treat turbid damp obstructing in middle-JIAO, The vomiting of gastral cavity painful abdominal mass, heat-damp in summer exterior syndrome, hygropyrexia from the beginning of, heating asthenia, uncomfortable in chest relax, cold-damp close summer-heat, stomachache vomit and diarrhoea.Radix Bupleuri nature and flavor are bitter, micro- Cold, return liver, gallbladder meridian；Have reconciling superficies and interior, effect of soothing the liver yang invigorating；Can be used for alternate attack of chill and fever, stagnation of QI due to depression of the liver and sternal rib pain etc.. Aloe has the effect of pathogenic fire purging, removing toxic substances, blood stasis dispelling, parasite killing；Can be used for treating constipation, nebulousurine, hematuria, carbuncle furuncle and phyma poison etc., and have and kill Let out under bacterium antiinflammatory, moistening beauty treatment, stomach invigorating, the effect of the defying age that detoxifies.
It addition, for the slimming medicine for external use of the present invention, the specialized designs of the present invention slimming of the preparation present invention The method of medicine for external use:
Fig. 1 is the flow chart of the slimming method for preparing externally applied in the embodiment of the present invention, as it is shown in figure 1, a kind of power Profit requires the preparation method of the slimming medicine for external use described in any one of 1-5, comprises the following steps:
S101: each raw material components is cleaned, dries rear cutout and be broken to 3-30 mesh.Wherein, each raw material components is shredded to 20 mesh.
Each raw material components is cleaned, dries rear cutout and be broken to 3-30 mesh, because active component is extracted in each raw material components Ratio and the degree of grinding of effective percentage and each raw material components there is the biggest relation, by each raw material components to 3-30 mesh, permissible The many active component in each raw material components is leached of most effective and most probable.
S102: Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and the mentha leave supercritical fluid of chopping to 3-30 mesh are extracted；Its In, the temperature of extraction is 43 DEG C-47 DEG C, and pressure is 13.50MPa-18.50MPa, and the time of extraction is 2h-3h.Wherein, described Supercritical fluid is CO2；The temperature of extraction is 46 DEG C, and pressure is 15.45MPa.
S103: be centrifuged separating under conditions of rotating speed is 2500-3800r/min by the product after extraction, take supernatant Liquid；Wherein, the time of centrifugation is 5min-10min.
Using supercritical fluid is 43 DEG C-47 DEG C in temperature, and pressure is 13.50MPa-18.50MPa and extraction time is Under conditions of 2h-3h, the effective ingredient in Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave is extracted, in each raw material components effectively Composition has special dissolution in supercritical fluid, effectively extracts each raw material components, i.e. under selected parameter To greatest extent the active substance in each raw material components can be proposed under low temperature state, and each active substance will not be destroyed Activity；Applicant finds through great many of experiments: be 43 DEG C-47 DEG C in temperature, when pressure 13.50MPa-18.50MPa and extraction Between for utilizing supercritical extraction technique that Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and the mentha leave of the present invention are extracted under conditions of 2h-3h Take, the slimming medicine action effect finally prepared can be made more preferable, can more effectively penetrate into skin and play combustion fat fall Effect of fat.Product after extraction is carried out under conditions of rotating speed is 2500-3800r/min centrifugal point of 5min-10min From, under high-speed separation state, the active substance extracted is separated with other impurity components, thus obtain rich in Pericarpium Citri Reticulatae, red The supernatant of effective ingredient in flower, Herba Apocyni veneti and mentha leave.
S104: by the chopping in addition to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave to other raw material components of 3-30 purpose and acetic acid Ethyl ester filters after being heated to reflux 2.5h-4.5h under conditions of 58 DEG C-68 DEG C after mixing by the weight ratio of 1:3-1:5, takes filtrate. Wherein, the temperature being heated to reflux is 63 DEG C, and the time being heated to reflux is 3.5h.
By the chopping in addition to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave to other raw material components of 3-30 purpose and ethyl acetate Filter after being heated to reflux 2.5h-4.5h under conditions of 58 DEG C-68 DEG C after mixing by the weight ratio of 1:3-1:5, take filtrate；Use Ethyl acetate to except Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti with mentha leave in addition to chopping effectively become to other raw material components of 3-30 purpose Point extraction, extraction ratio is high and does not interferes with the performance of each effective ingredient；Applicant finds through great many of experiments: by Pericarpium Citri Reticulatae, red Flower, Herba Apocyni veneti and mentha leave carry out supercritical fluid extraction by other raw material groups in addition to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave Point carry out ethyl acetate extraction, the drug effect of slimming medicine for external use finally prepared can be made more preferable, skin permeation after-burning fat Fat reducing effect is higher, and the speed of action during use is faster and without any side effects to human body.
S105: being 0.1Pa-0.08Pa in vacuum after being mixed with filtrate by supernatant, temperature is the condition of 65 DEG C-75 DEG C Under be dried 100min-200min.
Being 0.1Pa-0.08Pa in vacuum after being mixed with filtrate by supernatant, temperature is dry under conditions of being 65 DEG C-75 DEG C Dry 100min-200min；Pressure under vacuum condition is consistently lower than atmospheric pressure, and gas molecula number is few, and density is low, oxygen content It is low, so that the working substance mass-energy in each extract preferably keeps primary characteristic in dry run；And, its heating is all Even, from inside to outside the active substance in each extract is heated simultaneously, the internal-external temperature difference of each active substance is the least, will not produce The situation that in raw conventional heating, the interior external heat of appearance is inconsistent, thus do not interfere with the medicine of the slimming medicine for external use prepared Effect；Being 0.1Pa-0.08Pa in vacuum, temperature is dried 100min-200min under conditions of being 65 DEG C-75 DEG C, can make supernatant Active substance in liquid and filtrate is the driest, and makes best its original character of holding of each active substance.
S106: the product after dry 100min-200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.To be dried Product after 100min-200min is mixed by the weight ratio of 8:2 with extraction quintessence oil；According to the weight ratio of 8:2 by dried product Thing mixes with extraction quintessence oil, and the weight reducing that can strengthen the present invention in need not thinking each raw material components while effective ingredient activity subtracts The permeability of fertile medicine for external use, thus it is more conducive to skin absorption so that the action time of medicine of the present invention is more rapid.
Illustrate below in conjunction with detailed description of the invention:
Embodiment one
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 55 weight portions, Folium Perillae 27 weight portion, Flos Carthami 23 weight portion, Fructus Crataegi 45 weight portion, Semen Cassiae 15 weight portion, Herba Apocyni veneti 39 weight Part, the Rhizoma Anemarrhenae 29 weight portion, mentha leave 18 weight portion, Semen Coicis 25 weight portion, Flos Lonicerae 27 weight portion, Pericarpium Citri Reticulatae 9 weight portion, lemon grass (Cymbopogon citratus) 35 weight portions, Herba Pogostemonis 8 weight portion, Radix Bupleuri 12 weight portion and Aloe 23 weight portion.
By above-mentioned raw materials component, the preparation method of the slimming medicine for external use of present invention offer is provided, prepares slimming Medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 20 mesh；By chopping to the Pericarpium Citri Reticulatae of 20 mesh, Flos Carthami, Herba Apocyni veneti and thin Folium Nelumbinis supercritical CO2Extract；Wherein, the temperature of extraction is 46 DEG C, and pressure is 15.45MPa, and the time of extraction is 3h； It is centrifuged separating 10min under conditions of rotating speed is 3500r/min by the product after extraction, takes supernatant；Will be except Pericarpium Citri Reticulatae, red Chopping outside flower, Herba Apocyni veneti and mentha leave presses the weight ratio of 1:5 at 63 DEG C to other raw material components of 20 purposes and ethyl acetate Under the conditions of be heated to reflux after 3.5h filtering, take filtrate；Being 0.1Pa in vacuum after being mixed with filtrate by supernatant, temperature is 70 200min it is dried under conditions of DEG C；Product after dry 200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Embodiment two
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 43 weight portions, Folium Perillae 23 weight portion, Flos Carthami 29 weight portion, Fructus Crataegi 37 weight portion, Semen Cassiae 17 weight portion, Herba Apocyni veneti 40 weight Part, the Rhizoma Anemarrhenae 30 weight portion, mentha leave 25 weight portion, Semen Coicis 23 weight portion, Flos Lonicerae 28 weight portion, Pericarpium Citri Reticulatae 7 weight portion, lemon grass (Cymbopogon citratus) 35 weight portions, Herba Pogostemonis 9 weight portion, Radix Bupleuri 10 weight portion and Aloe 25 weight portion.
By above-mentioned raw materials component, the preparation method of the slimming medicine for external use of present invention offer is provided, prepares slimming Medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 20 mesh；By chopping to the Pericarpium Citri Reticulatae of 20 mesh, Flos Carthami, Herba Apocyni veneti and thin Folium Nelumbinis supercritical CO2Extract；Wherein, the temperature of extraction is 46 DEG C, and pressure is 15.45MPa, and the time of extraction is 3h； It is centrifuged separating 10min under conditions of rotating speed is 3500r/min by the product after extraction, takes supernatant；Will be except Pericarpium Citri Reticulatae, red Chopping outside flower, Herba Apocyni veneti and mentha leave presses the weight ratio of 1:5 at 63 DEG C to other raw material components of 20 purposes and ethyl acetate Under the conditions of be heated to reflux after 3.5h filtering, take filtrate；Being 0.1Pa in vacuum after being mixed with filtrate by supernatant, temperature is 70 200min it is dried under conditions of DEG C；Product after dry 200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Embodiment three
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 30 weight portions, Folium Perillae 30 weight portion, Flos Carthami 15 weight portion, Fructus Crataegi 60 weight portion, Semen Cassiae 10 weight portion, Herba Apocyni veneti 30 weight Part, the Rhizoma Anemarrhenae 35 weight portion, mentha leave 10 weight portion, Semen Coicis 35 weight portion, Flos Lonicerae 20 weight portion, Pericarpium Citri Reticulatae 10 weight portion and lemon Lemon grass 40 weight portions.
By above-mentioned raw materials component, the preparation method of the slimming medicine for external use of present invention offer is provided, prepares slimming Medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 30 mesh；By chopping to the Pericarpium Citri Reticulatae of 30 mesh, Flos Carthami, Herba Apocyni veneti and thin Folium Nelumbinis supercritical CO2Extract；Wherein, the temperature of extraction is 43 DEG C, and pressure is 13.50MPa, and the time of extraction is 2h； It is centrifuged separating 5min under conditions of rotating speed is 2500r/min by the product after extraction, takes supernatant；Will be except Pericarpium Citri Reticulatae, red Chopping outside flower, Herba Apocyni veneti and mentha leave presses the weight ratio of 1:3 at 63 DEG C to other raw material components of 30 purposes and ethyl acetate Under the conditions of be heated to reflux after 2.5h filtering, take filtrate；Being 0.08Pa in vacuum after being mixed with filtrate by supernatant, temperature is 65 100min it is dried under conditions of DEG C；Product after dry 100min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Embodiment four
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 70 weight portions, Folium Perillae 20 weight portion, Flos Carthami 35 weight portion, Fructus Crataegi 30 weight portion, Semen Cassiae 20 weight portion, Herba Apocyni veneti 50 weight Part, the Rhizoma Anemarrhenae 20 weight portion, mentha leave 30 weight portion, Semen Coicis 15 weight portion, Flos Lonicerae 35 weight portion, Pericarpium Citri Reticulatae 5 weight portion and lemon Lemon grass 25 weight portions.
By above-mentioned raw materials component, the preparation method of the slimming medicine for external use of present invention offer is provided, prepares slimming Medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 3 mesh；Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and Herba Menthae by chopping to 3 mesh Leaf supercritical CO2Extract；Wherein, the temperature of extraction is 47 DEG C, and pressure is 18.50MPa, and the time of extraction is 3h；Will Product after extraction is centrifuged separating 10min under conditions of rotating speed is 3800r/min, takes supernatant；Will be except Pericarpium Citri Reticulatae, red Chopping outside flower, Herba Apocyni veneti and mentha leave to other raw material components of 3 purposes and ethyl acetate presses the bar that the weight ratio of 1:5 is at 68 DEG C Filter after being heated to reflux 4.5h under part, take filtrate；Being 0.09Pa in vacuum after being mixed with filtrate by supernatant, temperature is 75 DEG C Under conditions of be dried 200min；Product after dry 200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Embodiment five
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 65 weight portions, Folium Perillae 23 weight portion, Flos Carthami 30 weight portion, Fructus Crataegi 35 weight portion, Semen Cassiae 18 weight portion, Herba Apocyni veneti 45 weight Part, the Rhizoma Anemarrhenae 25 weight portion, mentha leave 25 weight portion, Semen Coicis 20 weight portion, Flos Lonicerae 30 weight portion, Pericarpium Citri Reticulatae 6 weight portion, lemon grass (Cymbopogon citratus) 29 weight portions, Herba Pogostemonis 7 weight portion, Radix Bupleuri 13 weight portion and Aloe 18 weight portion.
By above-mentioned raw materials component, the preparation method of the slimming medicine for external use of present invention offer is provided, prepares slimming Medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 10 mesh；By chopping to the Pericarpium Citri Reticulatae of 10 mesh, Flos Carthami, Herba Apocyni veneti and thin Folium Nelumbinis supercritical CO2Extract；Wherein, the temperature of extraction is 44 DEG C, and pressure is 16.50MPa, and the time of extraction is 2.5h；It is centrifuged separating 8min under conditions of rotating speed is 3000r/min by the product after extraction, takes supernatant；Will be except old Chopping outside skin, Flos Carthami, Herba Apocyni veneti and mentha leave presses the weight ratio of 1:4 60 to other raw material components of 10 purposes and ethyl acetate Filter after being heated to reflux 3.5h under conditions of DEG C, take filtrate；It is 0.08Pa in vacuum after supernatant is mixed with filtrate, temperature 150min it is dried under conditions of being 70 DEG C；Product after dry 150min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Embodiment six
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 40 weight portions, Folium Perillae 29 weight portion, Flos Carthami 19 weight portion, Fructus Crataegi 58 weight portion, Semen Cassiae 13 weight portion, Herba Apocyni veneti 33 weight Part, the Rhizoma Anemarrhenae 30 weight portion, mentha leave 15 weight portion, Semen Coicis 30 weight portion, Flos Lonicerae 23 weight portion, Pericarpium Citri Reticulatae 9 weight portion, lemon grass (Cymbopogon citratus) 38 weight portions, Herba Pogostemonis 10 weight portion, Radix Bupleuri 8 weight portion and Aloe 30 weight portion.
By above-mentioned raw materials component, the preparation method of the slimming medicine for external use of present invention offer is provided, prepares slimming Medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 25 mesh；By chopping to the Pericarpium Citri Reticulatae of 25 mesh, Flos Carthami, Herba Apocyni veneti and thin Folium Nelumbinis supercritical CO2Extract；Wherein, the temperature of extraction is 46 DEG C, and pressure is 17.50MPa, and the time of extraction is 2.5h；It is centrifuged separating 7min under conditions of rotating speed is 3500r/min by the product after extraction, takes supernatant；Will be except old Chopping outside skin, Flos Carthami, Herba Apocyni veneti and mentha leave presses the weight ratio of 1:3 65 to other raw material components of 25 purposes and ethyl acetate Filter after being heated to reflux 3h under conditions of DEG C, take filtrate；Being 0.1Pa in vacuum after being mixed with filtrate by supernatant, temperature is 120min it is dried under conditions of 73 DEG C；Product after dry 120min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
It addition, for the advantage of preparation method highlighting the slimming medicine for external use that the present invention provides further, carry out with Lower contrast experiment:
Comparative example one
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 55 weight portions, Folium Perillae 27 weight portion, Flos Carthami 23 weight portion, Fructus Crataegi 45 weight portion, Semen Cassiae 15 weight portion, Herba Apocyni veneti 39 weight Part, the Rhizoma Anemarrhenae 29 weight portion, mentha leave 18 weight portion, Semen Coicis 25 weight portion, Flos Lonicerae 27 weight portion, Pericarpium Citri Reticulatae 9 weight portion, lemon grass (Cymbopogon citratus) 35 weight portions, Herba Pogostemonis 8 weight portion, Radix Bupleuri 12 weight portion and Aloe 23 weight portion.
By above-mentioned raw materials component, prepare slimming medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 20 mesh；To shred to the 20 each raw material components of purpose and ethyl acetate Filter after being heated to reflux 3.5h by the weight ratio of 1:5 under conditions of 63 DEG C, take filtrate；It is 0.1Pa by filtrate in vacuum, temperature Degree is dried 200min under conditions of being 70 DEG C；Product after dry 200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Comparative example two
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 55 weight portions, Folium Perillae 27 weight portion, Flos Carthami 23 weight portion, Fructus Crataegi 45 weight portion, Semen Cassiae 15 weight portion, Herba Apocyni veneti 39 weight Part, the Rhizoma Anemarrhenae 29 weight portion, mentha leave 18 weight portion, Semen Coicis 25 weight portion, Flos Lonicerae 27 weight portion, Pericarpium Citri Reticulatae 9 weight portion, lemon grass (Cymbopogon citratus) 35 weight portions, Herba Pogostemonis 8 weight portion, Radix Bupleuri 12 weight portion and Aloe 23 weight portion.
By above-mentioned raw materials component, prepare slimming medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 20 mesh；By chopping to 20 purpose each raw material components supercritical CO2 Extract；Wherein, the temperature of extraction is 46 DEG C, and pressure is 15.45MPa, and the time of extraction is 3h；Product after extraction is existed Rotating speed is to be centrifuged under conditions of 3500r/min separating 10min, takes supernatant；It is 0.1Pa by supernatant in vacuum, temperature Degree is dried 200min under conditions of being 70 DEG C；Product after dry 200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Comparative example three
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 55 weight portions, Folium Perillae 27 weight portion, Flos Carthami 23 weight portion, Fructus Crataegi 45 weight portion, Semen Cassiae 15 weight portion, Herba Apocyni veneti 39 weight Part, the Rhizoma Anemarrhenae 29 weight portion, mentha leave 18 weight portion, Semen Coicis 25 weight portion, Flos Lonicerae 27 weight portion, Pericarpium Citri Reticulatae 9 weight portion, lemon grass (Cymbopogon citratus) 35 weight portions, Herba Pogostemonis 8 weight portion, Radix Bupleuri 12 weight portion and Aloe 23 weight portion.
By above-mentioned raw materials component, prepare slimming medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 20 mesh；By chopping to the Pericarpium Citri Reticulatae of 20 mesh, Flos Carthami, Herba Apocyni veneti and thin Folium Nelumbinis supercritical CO2Extract；Wherein, the temperature of extraction is 40 DEG C, and pressure is 12.50MPa, and the time of extraction is 3h； It is centrifuged separating 10min under conditions of rotating speed is 3500r/min by the product after extraction, takes supernatant；Will be except Pericarpium Citri Reticulatae, red Chopping outside flower, Herba Apocyni veneti and mentha leave presses the weight ratio of 1:5 at 55 DEG C to other raw material components of 20 purposes and ethyl acetate Under the conditions of be heated to reflux after 3.5h filtering, take filtrate；Being 0.1Pa in vacuum after being mixed with filtrate by supernatant, temperature is 70 200min it is dried under conditions of DEG C；Product after dry 200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Comparative example four
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 55 weight portions, Folium Perillae 27 weight portion, Flos Carthami 23 weight portion, Fructus Crataegi 45 weight portion, Semen Cassiae 15 weight portion, Herba Apocyni veneti 39 weight Part, the Rhizoma Anemarrhenae 29 weight portion, mentha leave 18 weight portion, Semen Coicis 25 weight portion, Flos Lonicerae 27 weight portion, Pericarpium Citri Reticulatae 9 weight portion, lemon grass (Cymbopogon citratus) 35 weight portions, Herba Pogostemonis 8 weight portion, Radix Bupleuri 12 weight portion and Aloe 23 weight portion.
By above-mentioned raw materials component, prepare slimming medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 20 mesh；By chopping to the Pericarpium Citri Reticulatae of 20 mesh, Flos Carthami, Herba Apocyni veneti and thin Folium Nelumbinis supercritical CO2Extract；Wherein, the temperature of extraction is 50 DEG C, and pressure is 19.50MPa, and the time of extraction is 3h； It is centrifuged separating 10min under conditions of rotating speed is 3500r/min by the product after extraction, takes supernatant；Will be except Pericarpium Citri Reticulatae, red Chopping outside flower, Herba Apocyni veneti and mentha leave presses the weight ratio of 1:5 at 70 DEG C to other raw material components of 20 purposes and ethyl acetate Under the conditions of be heated to reflux after 3.5h filtering, take filtrate；Being 0.1Pa in vacuum after being mixed with filtrate by supernatant, temperature is 70 200min it is dried under conditions of DEG C；Product after dry 200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
Comparative example five
The present invention provides a kind of slimming medicine for external use, and raw material components by weight, is made up of following raw material components: big Yellow 55 weight portions, Folium Perillae 27 weight portion, Flos Carthami 23 weight portion, Fructus Crataegi 45 weight portion, Semen Cassiae 15 weight portion, Herba Apocyni veneti 39 weight Part, the Rhizoma Anemarrhenae 29 weight portion, mentha leave 18 weight portion, Semen Coicis 25 weight portion, Flos Lonicerae 27 weight portion, Pericarpium Citri Reticulatae 9 weight portion, lemon grass (Cymbopogon citratus) 35 weight portions, Herba Pogostemonis 8 weight portion, Radix Bupleuri 12 weight portion and Aloe 23 weight portion.
By above-mentioned raw materials component, prepare slimming medicine for external use:
Each raw material components is cleaned, dries rear cutout and be broken to 20 mesh；By chopping to the Pericarpium Citri Reticulatae of 20 mesh, Flos Carthami, Herba Apocyni veneti and thin Folium Nelumbinis supercritical CO2Extract；Wherein, the temperature of extraction is 46 DEG C, and pressure is 19.50MPa, and the time of extraction is 3h； It is centrifuged separating 10min under conditions of rotating speed is 3500r/min by the product after extraction, takes supernatant；Will be except Pericarpium Citri Reticulatae, red Chopping outside flower, Herba Apocyni veneti and mentha leave presses the weight ratio of 1:5 at 63 DEG C to other raw material components of 20 purposes and ethyl acetate Under the conditions of be heated to reflux after 3.5h filtering, take filtrate；Being 0.1Pa in vacuum after being mixed with filtrate by supernatant, temperature is 70 200min it is dried under conditions of DEG C；Product after dry 200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
The slimming medicine for external use embodiment of the present invention one to embodiment six, comparative example one to comparative example five obtained is logical Cross function assessment test come its effect of weight reducing of system evaluation:
One, toxicity test
The white mice selecting body weight to be 18-22g 20 (each 10 of male and female), takes the slimming medicine for external use 10g of the present invention, adds Deionized water makes concentrated solution 20ml, and every white mice gives concentrated solution 0.5ml gavage, every day twice；Observe 20 days, white mice The most healthy existence, without any side effects；Anatomic observation hemogram, liver function, each organs and tissues state, compare with normal white mice Zero difference.It is demonstrated experimentally that the slimming medicine for external use that the present invention provides is nontoxic.
Two, sensitivity test
Selecting the white rabbit 20 (each 10 of male and female) of 2-3kg, family's rabbit back unhairing exposes exocuticle, unhairing scope 5cm × 5cm, takes slimming medicine for external use 15g of the present invention, spreads upon on the exocuticle of rabbit, every day twice；Observe 20 days, be spaced 10 Reform after it hypersensitive test, observe after twice test, exocuticle does not finds erythema；Rabbit appetite, breathing, the equal nothing of the colour of skin Any exception.Thus proving, the outer used time dermoreaction of the slimming medicine for external use that the present invention provides is normal, without sensitization phenomenon.
Three, clinical trial
Administering mode: after cleaning skin, the slimming medicine for external use taking 0.1-0.3g is coated at SHENQUE acupoint, and presses gently Rub 15s-30s；Once a day, within 5 days, it is a course for the treatment of.
The international standard formulated according to WHO:
Normal adult standard body weight: (height cm-100cm) × 90%=standard body weight (kg).Wherein, overweight: body weight The 10% of the body weight that is above standard；Mild Obesity: the 20% of the body weight that is above standard；Central obesity: the 30% of the body weight that is above standard；Weight Degree obesity: the 50% of the body weight that is above standard.
The fat volunteer 3600 in call-up age 18-70 year；Wherein, Mild Obesity, central obesity and severe simple obesity are each 1100；Specifically, all kinds of volunteers are divided into 12 groups, the most often group include Mild Obesity person 100, central obesity person 100 Name and severe obesity 100；Wherein, the weight reducing of first group to the 6th group difference trial edition inventive embodiments one to embodiment six Fat-reducing medicine for external use；7th group of every day takes 2 commercially available green source of students diet teas；8th group to the 11st group try out comparative example one to The medicine that comparative example five obtains.After the slimming medicine for external use 5 days that trial edition invention provides, observed result.And with the 7th group of clothes Comparing by the using effect of 5 days green source of students diet teas, concrete condition is as shown in the table.
Bariatrician standard is divided into effective, effective and invalid；30% is reduced before effective finger weight ratio medication；Effectively refer to body 15% is reduced before anharmonic ratio medication；Before and after invalid finger medication, body weight is almost without change.
As can be seen here, the effective percentage of the slimming medicine for external use that the present invention provides is up to 100%；Wherein obvious effective rate is up to More than 90%, the obvious effective rate of the most commercially available green source of students diet tea about 40%；Additionally, by comparative example one to comparative example five Obvious effective rate, it can be seen that use the setting of extracting method of the test parameters that the present invention provides, the weight reducing prepared can be made The obvious effective rate of fat-reducing medicine for external use increases substantially.And, the slimming medicine for external use of the present invention, during application, is showed no red The phenomenons such as swollen, allergy；As a kind of pure natural without the slimming medicine for external use of hormonal substance, which obviate conventional commercial and be administered orally Slimming medicine detrimental effect that gastrointestinal function is caused, use outer application mode, easy to use, effect is rapidly.Meanwhile, to taking 3600 volunteers of slimming medicine of the present invention are tracked paying close attention to 1 year, find that obesity symptom is without bounce-back.
Certainly, situation about enumerating except embodiment one to embodiment six, the percentage by weight of other raw material components, supercritical Temperature that the type of fluid, extraction temperature, pressure and time, the rotating speed of centrifugation and time, ethyl acetate are heated to reflux and Time, vacuum drying temperature and and pulverize other mesh numbers also possible.Simply arrange in embodiment one to embodiment six In the case of act, more can effectively achieve the purpose of fat-reducing, act on the rapidest.And, applicant is sent out by substantial amounts of experiment Existing, use the special parameter in the raw material components of embodiment one and two and percentage by weight and preparation process, for preparing is thin The obvious effective rate of body fat-reducing medicine for external use is higher, and fat-reducing effect is more preferable.
The slimming medicine for external use that the present invention provides, by hot compress, allows the efficacy of a drug enter human body from SHENJUE acupoint, acts on noxious dampness The waist and belly of fat alluvial, toxin expelling desilting, naturally weight reducing, easy to use, effect rapidly, without rebounding and having no side effect, simultaneously Avoid the infringement to human stomach's function that oral drugs bring.
In the description of this specification, reference term " embodiment ", " some embodiments ", " example ", " specifically show Example " or the description of " some examples " etc. means to combine this embodiment or example describes specific features, structure, material or spy Point is contained at least one embodiment or the example of the present invention.In this manual, to the schematic representation of above-mentioned term not Identical embodiment or example must be directed to.And, the specific features of description, structure, material or feature can be in office One or more embodiments or example combine in an appropriate manner.Additionally, in the case of the most conflicting, the skill of this area The feature of the different embodiments described in this specification or example and different embodiment or example can be tied by art personnel Close and combination.
Although above it has been shown and described that embodiments of the invention, it is to be understood that above-described embodiment is example Property, it is impossible to being interpreted as limitation of the present invention, those of ordinary skill in the art within the scope of the invention can be to above-mentioned Embodiment is changed, revises, replaces and modification.

Claims (9)

1. a slimming medicine for external use, it is characterised in that raw material components by weight, including:
Radix Et Rhizoma Rhei 30-70 weight portion, Folium Perillae 20-30 weight portion, Flos Carthami 15-35 weight portion, Fructus Crataegi 30-60 weight portion, Semen Cassiae 10- 20 weight portions, Herba Apocyni veneti 30-50 weight portion, Rhizoma Anemarrhenae 20-35 weight portion, mentha leave 10-30 weight portion, Semen Coicis 15-35 weight portion, Flos Lonicerae 20-35 weight portion, Pericarpium Citri Reticulatae 5-10 weight portion and lemon grass (Cymbopogon citratus) 25-40 weight portion.
Slimming medicine for external use the most according to claim 1, it is characterised in that also include:
Herba Pogostemonis 5-10 weight portion, Radix Bupleuri 8-15 weight portion and Aloe 15-30 weight portion.
Slimming medicine for external use the most according to claim 2, it is characterised in that be made up of following raw material components:
Radix Et Rhizoma Rhei 40-65 weight portion, Folium Perillae 23-29 weight portion, Flos Carthami 19-30 weight portion, Fructus Crataegi 35-58 weight portion, Semen Cassiae 13- 18 weight portions, Herba Apocyni veneti 33-45 weight portion, Rhizoma Anemarrhenae 25-30 weight portion, mentha leave 15-25 weight portion, Semen Coicis 20-30 weight portion, Flos Lonicerae 23-30 weight portion, Pericarpium Citri Reticulatae 6-9 weight portion, lemon grass (Cymbopogon citratus) 29-38 weight portion, Herba Pogostemonis 7-9 weight portion, Radix Bupleuri 10-13 weight Part and Aloe 18-25 weight portion.
Slimming medicine for external use the most according to claim 3, it is characterised in that be made up of following raw material components:
Radix Et Rhizoma Rhei 55 weight portion, Folium Perillae 27 weight portion, Flos Carthami 23 weight portion, Fructus Crataegi 45 weight portion, Semen Cassiae 15 weight portion, Herba Apocyni veneti 39 weight portions, the Rhizoma Anemarrhenae 29 weight portion, mentha leave 18 weight portion, Semen Coicis 25 weight portion, Flos Lonicerae 27 weight portion, Pericarpium Citri Reticulatae 9 weight portion, Lemon grass (Cymbopogon citratus) 35 weight portion, Herba Pogostemonis 8 weight portion, Radix Bupleuri 12 weight portion and Aloe 23 weight portion.
Slimming medicine for external use the most according to claim 3, it is characterised in that be made up of following raw material components:
Radix Et Rhizoma Rhei 43 weight portion, Folium Perillae 23 weight portion, Flos Carthami 29 weight portion, Fructus Crataegi 37 weight portion, Semen Cassiae 17 weight portion, Herba Apocyni veneti 40 weight portions, the Rhizoma Anemarrhenae 30 weight portion, mentha leave 25 weight portion, Semen Coicis 23 weight portion, Flos Lonicerae 28 weight portion, Pericarpium Citri Reticulatae 7 weight portion, Lemon grass (Cymbopogon citratus) 35 weight portion, Herba Pogostemonis 9 weight portion, Radix Bupleuri 10 weight portion and Aloe 25 weight portion.
6. the preparation method of the slimming medicine for external use described in an any one of claim 1-5, it is characterised in that include following Step:
Each raw material components is cleaned, dries rear cutout and be broken to 3-30 mesh；
Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and the mentha leave supercritical fluid of chopping to 3-30 mesh are extracted；Wherein, extraction Temperature is 43 DEG C-47 DEG C, and pressure is 13.50MPa-18.50MPa, and the time of extraction is 2h-3h；
It is centrifuged separating under conditions of rotating speed is 2500-3800r/min by the product after extraction, takes supernatant；Wherein, from The time that the heart separates is 5min-10min；
By the chopping in addition to Pericarpium Citri Reticulatae, Flos Carthami, Herba Apocyni veneti and mentha leave to other raw material components of 3-30 purpose with ethyl acetate by 1: Filter after being heated to reflux 2.5h-4.5h under conditions of 58 DEG C-68 DEG C after the weight ratio mixing of 3-1:5, take filtrate；
Being 0.1Pa-0.08Pa in vacuum after being mixed with filtrate by supernatant, temperature is dried under conditions of being 65 DEG C-75 DEG C 100min-200min；
Product after dry 100min-200min is mixed by the weight ratio of 8:2 with extraction quintessence oil.
7. according to the preparation method of the above-mentioned slimming medicine for external use of claim 6, it is characterised in that:
Described supercritical fluid is CO2。
8. according to the preparation method of the above-mentioned slimming medicine for external use of claim 6, it is characterised in that:
The temperature of extraction is 46 DEG C, and pressure is 15.45MPa；
The temperature being heated to reflux is 63 DEG C, and the time being heated to reflux is 3.5h.
9. according to the preparation method of the above-mentioned slimming medicine for external use of claim 6, it is characterised in that:
Each raw material components is shredded to 20 mesh.
CN201610864690.4A 2016-09-29 2016-09-29 Slimming medicine for external use and preparation method thereof Pending CN106266789A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106963861A (en) * 2017-05-31 2017-07-21 宋志文 One kind fat-reducing dissipates
CN107183249A (en) * 2017-06-22 2017-09-22 厦门花沐春电子商务有限公司 Cleaning toxin, recuperating astriction and body-building disappear the health preserving tea and preparation method thereof of fat
CN107823357A (en) * 2017-11-23 2018-03-23 谭建军 A kind of green fat-reducing patch and preparation method thereof
CN108434314A (en) * 2018-04-24 2018-08-24 刘晓华 A kind of formula and application method of slimming
CN109010786A (en) * 2018-11-07 2018-12-18 云南魔瘦商贸有限公司 A kind of weight-losing plant powder and preparation method thereof
CN113181295A (en) * 2021-05-08 2021-07-30 莫超勇 Externally-applied traditional Chinese medicine powder with weight-losing effect and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432548A (en) * 2013-08-29 2013-12-11 张丽景 External use medicine for slimming
CN105288362A (en) * 2014-07-03 2016-02-03 河南省永传医药科技有限公司 Slimming traditional Chinese medicine honeyed pill
CN105796708A (en) * 2016-03-24 2016-07-27 长沙佰顺生物科技有限公司 Slimming and weight losing healthcare product

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432548A (en) * 2013-08-29 2013-12-11 张丽景 External use medicine for slimming
CN105288362A (en) * 2014-07-03 2016-02-03 河南省永传医药科技有限公司 Slimming traditional Chinese medicine honeyed pill
CN105796708A (en) * 2016-03-24 2016-07-27 长沙佰顺生物科技有限公司 Slimming and weight losing healthcare product

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106963861A (en) * 2017-05-31 2017-07-21 宋志文 One kind fat-reducing dissipates
CN107183249A (en) * 2017-06-22 2017-09-22 厦门花沐春电子商务有限公司 Cleaning toxin, recuperating astriction and body-building disappear the health preserving tea and preparation method thereof of fat
CN107823357A (en) * 2017-11-23 2018-03-23 谭建军 A kind of green fat-reducing patch and preparation method thereof
CN108434314A (en) * 2018-04-24 2018-08-24 刘晓华 A kind of formula and application method of slimming
CN109010786A (en) * 2018-11-07 2018-12-18 云南魔瘦商贸有限公司 A kind of weight-losing plant powder and preparation method thereof
CN113181295A (en) * 2021-05-08 2021-07-30 莫超勇 Externally-applied traditional Chinese medicine powder with weight-losing effect and preparation method thereof

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