CN105727128A - Traditional Chinese medicinal prescription for treating gastric cancer and preparation method of traditional Chinese medicinal prescription - Google Patents
Traditional Chinese medicinal prescription for treating gastric cancer and preparation method of traditional Chinese medicinal prescription Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicinal prescription for treating gastric cancer and a preparation method of the traditional Chinese medicinal prescription. The traditional Chinese medicinal prescription is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 2-3 parts of seed of garden balsam, 5-10 parts of rhizoma paridis chinensis, 5-10 parts of American ginseng, 5-10 parts of panax notoginseng powder, 5-15 parts of roasted rhizoma atractylodis macrocephalae, 3-5 parts of radix actinidiae chinensis, 2-3 parts of fructus camptothecae, 2-3 parts of smilacis chinae rhizoma, 3-5 parts of rhizoma corydalis, 2-3 parts of rhizoma cyperi, 3-5 parts of katsumade galangal seed, 2-3 parts of fructus polygoni orientalis, 10-20 parts of raw radix astragali, 3-5 parts of rhizoma galangae, 3-5 parts of dandelion, 3-5 parts of fructus amomi, 2-3 parts of radix paeoniae alba and 3-5 parts of liquorice root. Since the traditional Chinese medicines are effective on nourishing yin and promoting secretion of body fluid, strengthening body resistance, relieving swelling and eliminating stagnation, the traditional Chinese medicinal prescription disclosed by the invention can inhibit tumor breeding, control spread and transfer of the gastric cancer and boost immunity of patients; and in addition, the traditional Chinese medicinal prescription is capable of relieving pain and eliminating tumor, relieving pain in the patients and saving patients' lives.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly to a kind of Chinese medicine formula treating gastric cancer and preparation method thereof.
Background technology
Gastric cancer ranks first in the various malignant tumor of China.Early gastric cancer majority patient's non-evident sympton, a few peoples have Nausea and vomiting or the digestive symptoms of similar Peptic Ulcers.Pain is with to lose weight be the modal clinical symptoms of advanced gastric carcinoma.The digestive symptoms that patient Chang You is comparatively clear and definite, as epigastric discomfort, feed after glutted, along with sb.'s illness took a turn for the worse progress increase the weight of for Upper abdominal pain, appetite decline, weak.The symptoms such as late gastric cancer patient often may occur in which anemia, becomes thin, malnutrition even cachexia.
For the treatment of gastric cancer, current I, II phase gastric cancer, based on surgical radical treatment excision, postoperative II phase gastric cancer is it is contemplated that carry out chemotherapy and treatment by Chinese herbs；III phase gastric cancer is striven for making radical excision, if really can not make radical correction, makes palliative resection；IV phase gastric cancer and without obvious metastasis person, wherein some cases can make radical surgery or palliative resection, it is impossible to excision person make short circuit operation, postoperative employing chemotherapeutic treatment.But all defective property of method of operation and chemotherapeutic treatment, operative treatment is the means of local treatment, like water off a duck's back for the tumor cell transferred in blood or its hetero-organization；Chemotherapy can effectively hinder cancerous cell, but can kill normal cell again simultaneously and cause that the immunologic function of patient is suppressed, and more complication occurs, brings very big damage to patient body.Chinese patent (CN102861193A) discloses a kind of Chinese medicine treating gastric cancer, there is the effect of dispersing swelling and dissipating binds, detoxicating and fighting cancer, but it is effective only for Vitro Tumor experiment and mouse experiment, the therapeutic effect of actual patient is remained to be discussed, treatment cycle does not explain yet, and actual popularization has certain restriction.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine formula treating gastric cancer and preparation method thereof, by the YIN nourishing and the production of body fluid promoting of Chinese medicine, strengthening the body resistance, dispersing swelling and dissipating binds effect, it is suppressed that tumor propagation, control tumor diffusion transfer, enhancing immunity, and can pain relieving dispersing tumor, alleviate patient's misery, save patients ' lives.
The present invention provides a kind of Chinese medicine formula treating gastric cancer, formulated by the raw material of Chinese medicine of following parts by weight: Semen Impatientis 2～3 parts, Rhizoma Paridis 5～10 parts, Radix Panacis Quinquefolii 5～10 parts, Radix Notoginseng powder 5～10 parts, Rhizoma Atractylodis Macrocephalae (parched) 5～15 parts, Radix Actinidiae Chinensis 3～5 parts, Fructus Camptothecae Acuminatae 2～3 parts, Rhizoma Smilacis Chinensis 2～3 parts, Rhizoma Corydalis 3～5 parts, Rhizoma Cyperi 2～3 parts, Semen Alpiniae Katsumadai 3～5 parts, Fructus Polygoni Orientalis 2～3 parts, Radix Astragali 10～20 parts, Rhizoma Alpiniae Officinarum 3～5 parts, Herba Taraxaci 3～5 parts, Fructus Amomi 3～5 parts, the Radix Paeoniae Alba 2～3 parts, 3～5 parts of Radix Glycyrrhizae.
It is preferred that be that the raw material of Chinese medicine by following parts by weight is formulated: Semen Impatientis 3 parts, Rhizoma Paridis 8 parts, Radix Panacis Quinquefolii 6 parts, Radix Notoginseng powder 6 parts, Rhizoma Atractylodis Macrocephalae (parched) 8 parts, Radix Actinidiae Chinensis 4 parts, Fructus Camptothecae Acuminatae 5 parts, Rhizoma Smilacis Chinensis 3 parts, Rhizoma Corydalis 3 parts, Rhizoma Cyperi 2 parts, Semen Alpiniae Katsumadai 4 parts, Fructus Polygoni Orientalis 2 parts, Radix Astragali 15 parts, Rhizoma Alpiniae Officinarum 4 parts, Herba Taraxaci 4 parts, Fructus Amomi 4 parts, the Radix Paeoniae Alba 3 parts, 4 parts of Radix Glycyrrhizae.
Preparation method is made up of following steps: weigh raw material of Chinese medicine by above-mentioned weight portion, adds cold water, did not have medical material 2～5cm, and soaked 1～2 hour；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 20～40min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged.
Pharmacology analysis:
Semen Impatientis: micro-hardship, pungent, temperature, slightly poisonous；Return spleen, Liver Channel.Function relieves internal heat the detumescence of anticancer, scattered silt.Removing blood stasis softening the hard mass, removing food stagnancy.For abdominal mass mass in the abdomen, amenorrhea, dysphagic.Drug sensitive test proves that it is to gastric lymphosarcoma sensitizing cells；Sarcoma-37 there is inhibitory action.
Rhizoma Paridis: hardship is slightly cold mild toxicity, enters Liver Channel.Function heat-clearing and toxic substances removing, reducing swelling and alleviating pain, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. and determine convulsion；Curing mainly digestive tract carcinoma, pulmonary carcinoma, the cerebral tumor and malignant lymphoma, clinic is used for the stagnant malignant lymphoma of pyretic toxicity harmony, pulmonary carcinoma, nasopharyngeal carcinoma, the cerebral tumor and digestive system tumor such as gastric cancer, the esophageal carcinoma, hepatocarcinoma etc..
Radix Panacis Quinquefolii: cool in nature, sweet in the mouth, micro-hardship.Function boosting qi and nourishing yin, clearing away heat and promoting production of body fluid；For deficiency of vital energy yin deficiency, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, and dry mouth larynx is done.Lung benefiting is cloudy, clear asthenic fire, promoting the production of body fluid to quench thirst.Controlling deficiency of the lung chronic cough, lose blood, dry throat and mouth, deficiency-heat is tired of tired.
Radix Notoginseng powder: sweet in the mouth, micro-hardship, warm in nature, return lung, stomach, the heart, liver, large intestine channel.Function hemostasis dissipating blood stasis, subduing swelling and relieving pain, hemopoietic of enriching blood.Curing mainly obstruction of qi in the chest and cardialgia, blood stasis amenorrhea, lump in the abdomen, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, and spits blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, treating swelling and pain by traumatic injury, sore and toxic etc..Radix Notoginseng can be led to and can be mended, and can dissipate and can receive.
Rhizoma Atractylodis Macrocephalae (parched): bitter in the mouth, sweet, warm in nature, return spleen, stomach warp.Function invigorating the spleen and benefiting QI, dampness diuretic, strengthening superficial resistance to stop perspiration, antiabortive.Can treating insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, spontaneous sweating due to deficiency of QI, phlegm retention edema, dysuria, and arthralgia chiefly caused by damp pathogen is ached and frequent fetal movement.Modern pharmacological research is reported, the Rhizoma Atractylodis Macrocephalae has hepatic cholagogic, anti-gastric-ulcer, diuresis, raising immunologic function, antitumor, calmness, blood pressure lowering, blood sugar lowering, anticoagulant, resisting pathogenic microbes, the effect such as antiabortive, strong.
Radix Actinidiae Chinensis: function heat-clearing and toxic substances removing, clearing away heat-damp and promoting diuresis, preventing tumor is anticancer, expelling wind and removing dampness, diuresis is stopped blooding, and removing toxic substances and promoting subsidence of swelling cures mainly the diseases such as dyspepsia, vomiting, rheumatic arthralgia, rheumatic ostalgia, Alimentary Tract Cancer, digestive tract tumor, carbuncle and ulcer furuncle, rheumatic ostalgia and jaundice.
Fructus Camptothecae Acuminatae: cold in nature, bitter in the mouth, puckery, poisonous.Function is anticancer, eliminating stagnation, removing blood stasis, for kinds of tumors, such as gastric cancer, intestinal cancer, chorionic epithelioma, lymphosarcoma etc..
Rhizoma Smilacis Chinensis: expelling wind and removing dampness, removing toxicity for eliminating carbuncles.Main air pain of dampness syndrome, stranguria with turbid discharge, leukorrhagia, have loose bowels, dysentery, carbuncle sore tumefacting virus, stubborn dermatitis, burn and scald；Removing toxic substances, wind dispelling, skin ulcer section key medicine, there is a diaphoresis, wind dispelling, diuresis and control gonorrhea, cancer, the function of diabetes. wherein better with gastric cancer and esophageal carcinoma effect；Leaf is mashed lemma and is controlled malignant boil.
Rhizoma Corydalis: warm in nature, acrid in the mouth is bitter, enters the heart, spleen, liver, lung, is the quality goods of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, is especially world-famous for effect of pain relieving.Li Shizhen (1518-1593 A.D.) concludes Rhizoma Corydalis in Compendium of Material Medica " invigorate blood circulation, regulate the flow of vital energy, pain relieving, diuresis " four large effects, and praises highly Rhizoma Corydalis " can the stagnation of QI in promoting the circulation of blood, stasis in gas, therefore specially control upper and lower all pains all over the body ".
Rhizoma Cyperi: sweet in the mouth, is slightly cold, nontoxic；Enter liver, tri-jiao channel.Function is regulated the flow of vital energy resolving depression, and menstruction regulating and pain relieving is antiabortive；Curing mainly distending pain over the hypochondrium, mammary swelling is educated, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea；Abdominal pain during menstruation；Bleeding not during menses；Frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Semen Alpiniae Katsumadai: pungent, temperature；Return lung meridian, spleen channel, stomach warp.Function removing dampness disappears painful abdominal mass, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving；Cure mainly for turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, uncomfortable in chest not hungry, cold-damp vomiting, chest and abdomen swelling and pain, food stagnation does not disappear.
Fructus Polygoni Orientalis: salty in the mouth, is slightly cold, nontoxic；Enter liver, stomach, spleen three warp.Function heat clearing away, softening the hard mass.Repercussive removing mass, invigorating spleen to remove dampness.Controlling flank disease to amass, dropsy, have a stomach-ache, lack of appetite abdominal distention, acute catarrhal conjunctivitis, skin ulcer swells, scrofula.
Radix Astragali: sweet in the mouth, slightly warm in nature, return spleen, lung meridian, enter edema caused by disorder of QI, can rise and can drop.Effect tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, line water detumescence, detoxification granulation promoting.Cure mainly internal injury overstrain, spiritlessness and weakness, diarrhea due to hypofunction of the spleen, cough due to deficiency of the lung, visceroptosis, failure of the spleen to keep the blood flowing within the vessels hemorrhage, spontaneous perspiration, night sweat etc..Ancient books " book on Chinese herbal medicine warp " is stated: " complement sun, fills space between skin and muscles, control impairment caused by overstrain, longue meat." " book on Chinese herbal medicine converge with speech " say: " tonifying the lung spleen invigorating, defends arresting sweating in fact, fortune of dispeling the wind poison." " in inner feelings ginseng west record medicine " state: " kind diuresis ", " kind control disabled wilted limbs." modern pharmacological research report, the Radix Astragali be significantly improved immunologic function, protection cardiac muscle, protect and improve hemopoietic system, antioxidation, defying age, antitumor, diuresis are protected kidney, are regulated the effect such as blood glucose, nervous system regulation, antibacterial, antiviral and facilitating digestion function.
Rhizoma Alpiniae Officinarum: nature and flavor temperature pungent, big, nontoxic.Returning spleen, stomach warp, function warming stomach for dispelling cold, help digestion pain relieving, cures mainly coldness and pain in the epigastrium, gastrofrigid vomiting, belch acid regurgitation.It it is the adjuvant drug for we.
Herba Taraxaci: sweet in the mouth, micro-hardship, cold in nature, return liver, stomach, kidney channel.Function heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dehumidify diuresis.Cure mainly the ulcerative carbuncle toxic swelling that all pyretic toxicity are caused, mumps, scrofula；The pharyngalgia that pathogenic heat is caused, conjunctival congestion, gastralgia, dysentery, jaundice, frequent micturition dysurea, cancer of the esophagus cancerous protuberance, worm venom etc..
Fructus Amomi: warm in nature, acrid in the mouth；Enter spleen, stomach warp；Function cures mainly in circulation of qi promoting tune, and stomach function regulating is amusing；Control stomachache painful abdominal mass swollen, anorexia dyspepsia, dysphagic vomiting, diarrhea due to cold pathogen cold-dysentery, gestation fetal movement.
Radix Glycyrrhizae: sweet in the mouth, property is put down；Enter spleen, stomach, lung meridian；Function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, clear throat, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
The Chinese medicine of the present invention, by the YIN nourishing and the production of body fluid promoting of Chinese medicine, strengthening the body resistance, dispersing swelling and dissipating binds effect, it is suppressed that tumor propagation, control tumor diffusion transfer, enhancing immunity, and can pain relieving dispersing tumor, alleviate patient's misery, save patients ' lives.
Outcome measure:
Effective: body constitution strengthens, limbs are strong, and abdominal discomfort disappears, and tumor stomach tumor body reduces, and other position has no nascent tumor,
Effective: body constitution strengthens, and tumor stomach has no increase, and other position has no nascent tumor；
Invalid: symptom is unchanged, tumor stomach tumor body increases, or nascent tumor occurs in other position.
Therapeutic outcome: treat 197 patients with gastric cancer, 1 month is a course for the treatment of, 1 day for oral administration 1 dose, take at twice.Use 2 the course for the treatment of present invention Chinese medicine after, effective 188 examples, account for 95.4%, effective 8 examples, account for 4.1%, invalid 1 example, account for 0.5%.
Attached a few example case is described further:
Case 1: Ma, female, 60 years old, because of epigastrium distending pain, sleep was severely impacted here and seeks medical advice, and gastroscopic observation and biopsy pathology are diagnosed as cancer at the bottom of cardia stomach.Exploratory laparotomy finding, tumor stomach is about 10cm × 8cm × 7cm size, fixes with pancreas adhesion, and the transfer of mesentery, peritoneum multiple nodules shape, do not do any excision and close abdomen.Then give Chinese medicine of the present invention to treat, effective after 2 courses for the treatment of, tumor disappearance after half a year, follow up a case by regular visits to half a year without recurrence.
Case 2: Hu, man, 46 years old, because occurring that gastral cavilty portion is uncomfortable without obvious inducement, is interrupted and takes the medicines such as motilium without improvement, and have gradually and increase the weight of to come here and seek medical advice.Gastroscopy shows that gastric cancer involves cardia；Taking pathology and show a little adenocarcinoma tissue of body of stomach (low differentiation), brushing piece finds cancerous cell, then gives medicine of the present invention, effective after using 2 courses for the treatment of, effective after 3 courses for the treatment of, follows up a case by regular visits to 1 year tumor without increasing phenomenon.
Detailed description of the invention
Embodiment 1:
A kind of Chinese medicine formula treating gastric cancer, formulated by the raw material of Chinese medicine of following parts by weight: Semen Impatientis 3 parts, Rhizoma Paridis 8 parts, Radix Panacis Quinquefolii 6 parts, Radix Notoginseng powder 6 parts, Rhizoma Atractylodis Macrocephalae (parched) 8 parts, Radix Actinidiae Chinensis 4 parts, Fructus Camptothecae Acuminatae 5 parts, Rhizoma Smilacis Chinensis 3 parts, Rhizoma Corydalis 3 parts, Rhizoma Cyperi 2 parts, Semen Alpiniae Katsumadai 4 parts, Fructus Polygoni Orientalis 2 parts, Radix Astragali 15 parts, Rhizoma Alpiniae Officinarum 4 parts, Herba Taraxaci 4 parts, Fructus Amomi 4 parts, the Radix Paeoniae Alba 3 parts, 4 parts of Radix Glycyrrhizae.
Preparation method is that preparation method is made up of following steps: weigh raw material of Chinese medicine by above-mentioned weight portion, adds cold water, did not have medical material 3cm, and soaked 1.5 hours；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 30min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged.
Embodiment 2:
A kind of Chinese medicine formula treating gastric cancer, formulated by the raw material of Chinese medicine of following parts by weight: Semen Impatientis 2 parts, Rhizoma Paridis 10 parts, Radix Panacis Quinquefolii 5 parts, Radix Notoginseng powder 10 parts, Rhizoma Atractylodis Macrocephalae (parched) 5 parts, Radix Actinidiae Chinensis 5 parts, Fructus Camptothecae Acuminatae 2 parts, Rhizoma Smilacis Chinensis 3 parts, Rhizoma Corydalis 3 parts, Rhizoma Cyperi 3 parts, Semen Alpiniae Katsumadai 3 parts, Fructus Polygoni Orientalis 3 parts, Radix Astragali 10 parts, Rhizoma Alpiniae Officinarum 5 parts, Herba Taraxaci 3 parts, Fructus Amomi 5 parts, the Radix Paeoniae Alba 2 parts, 5 parts of Radix Glycyrrhizae.
Preparation method is that preparation method is made up of following steps: weigh raw material of Chinese medicine by above-mentioned weight portion, adds cold water, did not have medical material 5cm, and soaked 1 hour；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 40min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged.
Embodiment 3:
A kind of Chinese medicine formula treating gastric cancer, formulated by the raw material of Chinese medicine of following parts by weight: Semen Impatientis 3 parts, Rhizoma Paridis 5 parts, Radix Panacis Quinquefolii 10 parts, Radix Notoginseng powder 5 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Radix Actinidiae Chinensis 3 parts, Fructus Camptothecae Acuminatae 3 parts, Rhizoma Smilacis Chinensis 2 parts, Rhizoma Corydalis 5 parts, Rhizoma Cyperi 2 parts, Semen Alpiniae Katsumadai 5 parts, Fructus Polygoni Orientalis 2 parts, Radix Astragali 20 parts, Rhizoma Alpiniae Officinarum 3 parts, Herba Taraxaci 5 parts, Fructus Amomi 3 parts, the Radix Paeoniae Alba 3 parts, 3 parts of Radix Glycyrrhizae.
Preparation method is that preparation method is made up of following steps: weigh raw material of Chinese medicine by above-mentioned weight portion, adds cold water, did not have medical material 2cm, and soaked 2 hours；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 20min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged.
Below the present invention is described in detail, the above, it is only the preferred embodiments of the invention, when the scope of the present invention can not be limited, namely all done impartial change according to the application scope and modify, all should still belong in covering scope of the present invention.
Claims (3)
1. the Chinese medicine formula treating gastric cancer, it is characterised in that formulated by the raw material of Chinese medicine of following parts by weight: Semen Impatientis 2～3 parts, Rhizoma Paridis 5～10 parts, Radix Panacis Quinquefolii 5～10 parts, Radix Notoginseng powder 5～10 parts, Rhizoma Atractylodis Macrocephalae (parched) 5～15 parts, Radix Actinidiae Chinensis 3～5 parts, Fructus Camptothecae Acuminatae 2～3 parts, Rhizoma Smilacis Chinensis 2～3 parts, Rhizoma Corydalis 3～5 parts, Rhizoma Cyperi 2～3 parts, Semen Alpiniae Katsumadai 3～5 parts, Fructus Polygoni Orientalis 2～3 parts, Radix Astragali 10～20 parts, Rhizoma Alpiniae Officinarum 3～5 parts, Herba Taraxaci 3～5 parts, Fructus Amomi 3～5 parts, the Radix Paeoniae Alba 2～3 parts, 3～5 parts of Radix Glycyrrhizae.
2. the Chinese medicine formula treating gastric cancer as claimed in claim 1, it is characterised in that formulated by the raw material of Chinese medicine of following parts by weight: Semen Impatientis 3 parts, Rhizoma Paridis 8 parts, Radix Panacis Quinquefolii 6 parts, Radix Notoginseng powder 6 parts, Rhizoma Atractylodis Macrocephalae (parched) 8 parts, Radix Actinidiae Chinensis 4 parts, Fructus Camptothecae Acuminatae 5 parts, Rhizoma Smilacis Chinensis 3 parts, Rhizoma Corydalis 3 parts, Rhizoma Cyperi 2 parts, Semen Alpiniae Katsumadai 4 parts, Fructus Polygoni Orientalis 2 parts, Radix Astragali 15 parts, Rhizoma Alpiniae Officinarum 4 parts, Herba Taraxaci 4 parts, Fructus Amomi 4 parts, the Radix Paeoniae Alba 3 parts, 4 parts of Radix Glycyrrhizae.
3. the method for the preparation Chinese medicine formula treating gastric cancer as claimed in claim 1, it is characterised in that be made up of following steps: weigh raw material of Chinese medicine by above-mentioned weight portion, add cold water, do not have medical material 2～5cm, and soaked 1～2 hour；Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 20～40min to；After cooked, leach medicine juice and decoct as head；Medicinal residues repeat the above steps is decocted, after cooked, the medicine juice of twice decoction is merged.
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