CN101700369B - Combination of medicines for treating gastric and intestinal cancer - Google Patents
Combination of medicines for treating gastric and intestinal cancer Download PDFInfo
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- CN101700369B CN101700369B CN2009102307174A CN200910230717A CN101700369B CN 101700369 B CN101700369 B CN 101700369B CN 2009102307174 A CN2009102307174 A CN 2009102307174A CN 200910230717 A CN200910230717 A CN 200910230717A CN 101700369 B CN101700369 B CN 101700369B
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a combination of medicines for treating gastric and intestinal cancer, which is prepared by the repeated verifications of clinical trails and conforms to the theory of traditional Chinese medical science. arctium lappa, white turnip, carrot, asparagus and aspongopus are taken as main medicines to clear heat, detoxify, resist cancer and eliminate evil; oldenlandia diffusa, hericium erinaceus and the like are taken as adjuvants to strengthen the effects of heat clearing and detoxification; airpotato yam rhizome, wild cordyceps sinensis and the like are utilized to tonify qi and nourish the stomach, warm meridians and relieve pain; and dindygulen peperomia herb, seaweed, royal jelly, musk and the like are used to tonify spleen and stomach, strengthen spleen and tonify lung and moisten intestines. The combination of medicines for treating stomach and intestine cancer of the invention has double effectiveness of health care, namely benefiting vital energy and nourishing the stomach, and reducing the harm to the stomach and intestine mucous membrane; the traditional Chinese medicine are selected to directly kill cancer cells and prevent neovascularization so that the cancer cells can not obtain enough supply of nutrition, the combination of medicines has unique effect for various stomach cancer patients, has incomparable wonderful effect compared with the modern medicines, and fundamentally relieves the plainness of the patients.
Description
Technical field
The present invention relates to a kind of Chinese medicine, a kind of specifically composition of medicine for the treatment of gastric and intestinal cancer.
Background technology
Human primary gastrointestinal cancers is the malignant tumor of digestive tract of seeing at most, and China belongs to the human primary gastrointestinal cancers district occurred frequently, and is wherein the highest with the Northwest.The recall rate of primary disease has the trend that increases year by year.Human primary gastrointestinal cancers was mainly in more than 40 years old, and 41-60 year person accounts for 2/3rds, and men and women's ratio is about 3.6: 1.The Therapeutic Method of human primary gastrointestinal cancers mainly contains operation, chemicotherapy and Chinese medicine clinically, and is the Therapeutic Principle with the combination of Chinese and Western medicine.
The treatment of early stage human primary gastrointestinal cancers is based on excision, if excision fully, the patient has the possibility that obtains long term survival, but a series of complication can appear in most of patients after surgery, and the patient of recurrence does not occupy the minority yet, therefore, the patient should carry out aftertreatment at the used after operation Chinese medicine, can alleviate the probability of recurrence on the one hand, suppresses recessive cancerous cell, can accelerate the recovery of patient body function on the other hand, alleviate post-operative complication.
The probability of middle and advanced stage human primary gastrointestinal cancers operation is little, also only is palliative local excision even if can perform the operation, and clinically, the comprehensive means of chemicotherapy associating Chinese medicine is adopted in the treatment of middle and advanced stage human primary gastrointestinal cancers more, with abundant advantage in conjunction with each Therapeutic Method.Chemicotherapy all has comparatively directly inhibitory action to cancerous cell, but the two also can cause damage to the human immune system, most of patients is after the radiotherapy of carrying out one period or chemotherapy, leukopenia can appear, bone marrow depression, alopecia, a series of symptoms such as weak, physical function seriously descends, and it is dead that excessive and irrational treatment can cause about 15% patient with advanced cancer to quicken, to treatment carry out smoothly unfavorable.Therefore, the middle and advanced stage gastrointestinal cancer patients should be treated in conjunction with Chinese medicine, the advantage of Chinese traditional treatment human primary gastrointestinal cancers is can strengthen on the one hand the therapeutic effect of chemicotherapy, improve its sensitivity, on the one hand can alleviate the damage of chemicotherapy, make that treatment is smooth function of human body, effect than simple western medical treatment for good, patient's life quality is higher, and life span is also longer.
Summary of the invention
The objective of the invention is to overcome the defective that exists in the prior art, a kind of composition of medicine for the treatment of gastric and intestinal cancer is provided.
Medicine of the present invention forms by the clinic tests and repeated verification configuration, meets the theory of Chinese medicine.With Fructus Arctii, white turnip, Radix Dauci Sativae, Germinatus Phragmitis, Aspongopus heat-clearing and toxic substances removing, anticancer eliminating evil be principal agent, be that accessory drugs is strengthened heat-clearing and toxic substances removing, anticancer effect with Herba Hedyotidis Diffusae, leaf of white turnip, Folium Dauci Sativae, Hericium erinaceus (Bull. Ex Fr.) Pers.; With Rhizoma Dioscoreae Bulbiferae, Herba Lobeliae Chinensis, Rhizoma Cimicifugae, the nourishing the stomach of wild cordyceps QI invigorating, antalgic; With spleen reinforcing stomach function regulating such as Herba Senecionis nudicaulis, Bombyx Batryticatus, Herba Peperomiae Dindygulensis, Herba Peperomiae Dindygulensis, Sargassum, Lac regis apis, Moschus, spleen invigorating lung benefiting, intestine moistening.The present invention keeps healthy to gastrointestinal mucosa infringement double effects from QI invigorating nourishing the stomach, minimizing and starts with, select the direct kill cancer cell of Chinese medicine medicine for use, the blocking-up new vessels generates, make cancerous cell can not obtain the prescribing adequate nutrition supply, various patients with gastric cancer had unique curative effect, the unrivaled miraculous effects of modern medicines are arranged, fundamentally removed patient's misery.
The medicine pharmacology of the present invention and the property of medicine:
Fructus Arctii:
[meridian distribution of property and flavor] suffering, hardship is trembled with fear into meridian of Hand-TAI YIN.
[function cures mainly] heat of dispeling the wind, the detumescence poison.Control the pathogenic wind toxic swelling of the face, dizziness, throat heat is swollen, toothache, carbuncle skin ulcer scabies is quenched one's thirst in cough.
White turnip:
[meridian distribution of property and flavor] sweet in the mouth, suffering, cool in nature are gone into lung, stomach, lung, large intestine channel.
[function cures mainly] has clearing away heat and promoting production of body fluid, cooling blood for hemostasis, therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, relieving dyspepsia, appetite promoting and the spleen strengthening, pleasant expectorant effect.Be mainly used in diseases such as abdominal distention is stopped eating, stomachache, cough, abundant expectoration.
Radix Dauci Sativae:
[meridian distribution of property and flavor] nature and flavor sweet in the mouth, property is flat.
[function] function strengthening the spleen to promote digestion, tonifying liver make eye bright, heat-clearing and toxic substances removing, rash, sending down the abnormal ascending QI cough-relieving.Being used for infantile malnutrition, measles, nyctalopia, constipation, hypertension, gastrointestinal upset, full stifling expands etc.
Germinatus Phragmitis:
[pharmacology value] 1, help to stabilize the blood pressure blood fat reducing; 2, help to suppress cardiovascular disease; 3, help prevention and anticancer; 4, help to prevent and treat senile constipation, diuresis is recovered from fatigue; 5, help to suppress and resist viral bacterium; 6, help the health invigorating allaying tiredness.
[nutritive value] 1, homovitamin, high-cellulose, high protein 2, low sugar, low fat 3, a great number of elements that contains multiple needed by human and trace element
[health-care effect] 1, cancer-resisting effect can suppress the topoisomerase enzymatic activity, directly kill cancerous cell, and the destruction of cancer cells telomerase makes the cancerous cell can not multiple fission and wither it, activates the antioncogene adjustment signal, transfer cell growth normalization.2, to the therapeutical effect of cardiovascular disease, Germinatus Phragmitis can suppress hypertension, prevents sclerosis of blood vessels, blood fat reducing and cholesterol.3, to human immune system's influence, Germinatus Phragmitis can reduce circulating immune complex CIC content, can produce thymosin, promotes the generation of T cell, thereby improves immunologic function, regulates immunologic mechanism.4, the effect aspect defying age can reduce the lipid peroxide of human organ, the content of LOP, thereby the activity slow down aging of raising superoxide dismutase SOD.
Aspongopus:
[meridian distribution of property and flavor] property is salty, hot, warm; Return stomach, liver, large intestine channel;
[effect] anticancer, the promoting the circulation of QI pain relieving that relieves internal heat.
Herba Hedyotidis Diffusae:
[meridian distribution of property and flavor] bitter but sweet flavor, warm in nature, nontoxic.Go into the heart, liver, spleen three warps.
[function cures mainly] hyoscine has the function of heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.Cure mainly diseases such as malignant tumor, appendicitis, hepatitis, bronchitis, tonsillitis, laryngitis, urinary system infection, pelvic inflammatory disease, adnexitis; Furuncle carbuncle, venom are controlled in external.The clinical multiple cancers such as gastric cancer, the esophageal carcinoma, intestinal cancer, uterus carcinoma, nasopharyngeal carcinoma that are used for the treatment of of modern Chinese medicine.
Leaf of white turnip
[nutritive value] contains abundant bata-carotene, and vitamin A content is 140IU in per 100 gram Folium Raphani, is more than three times of commensurability broccoli 400IU; And the content of calcium be per 300 the gram contain 210 milligrams, be 4 times of 55 milligrams of commensurability Herba Spinaciaes; Vitamin B1 Duos 60% than Semen Sojae Preparatum; 2 of vitamin betas are two times of beef.Can be used for clearing away lung-heat, sharp liver.
Folium Dauci Sativae:
[meridian distribution of property and flavor] property is sweet flat, returns lung heart spleen channel,
[function cures mainly] has the therapeutic method to keep the adverse QI flowing downwards, heat-clearing and toxic substances removing, the effect of invigorating middle warmer peace internal organs.Cure mainly dysphoria with smothery sensation, constipation, sensation of oppression over the chest with shortness of breath, poliomyelitis, dyspepsia, nyctalopia etc.
Hericium erinaceus (Bull. Ex Fr.) Pers.:
[meridian distribution of property and flavor] property is flat, sweet in the mouth; Return board, stomach, kidney channel.
[function cures mainly] sharp the five internal organs, aid digestion, have and be good for the stomach, tonify deficiency, anticancer, the effect of kidney tonifying essence; Cure mainly diseases such as anorexia and loose stool, gastric and duodenal ulcers, neurasthenia, esophageal carcinoma, gastric cancer, dizzy, sexual impotence; The edible Hericium erinaceus (Bull. Ex Fr.) Pers. of old person has the effect of nourishing and fit keeping function.
Rhizoma Dioscoreae Bulbiferae:
[meridian distribution of property and flavor] is bitter, hot, cold.Slightly poisonous.
[function cures mainly] removing toxic substances and promoting subsidence of swelling, dissipating phlegm and resolving masses, cooling blood for hemostasis.Be used for thyromegaly, tuberculous lymphadenitis, laryngopharynx swelling and pain is spitted blood, spitting of blood, pertussis, cancerous protuberance; Furuncle is controlled in external.
Herba Lobeliae Chinensis:
[meridian distribution of property and flavor] is hot, light, cool; Return liver, stomach, kidney, small intestine meridian.
[drug effect] relieve internal heat anticancer, diuretic heat clearing away, treat the skin ulcer detumescence.
Rhizoma Cimicifugae:
[meridian distribution of property and flavor] is sweet, hot, cool; Return spleen, stomach, large intestine channel.
[drug effect] relieve internal heat anticancer, rash is analgesic, doctor's skin ulcer eliminating carbuncle.
Wild cordyceps:
[nature and flavor] are sweet, temperature.[return through] goes into lung, kidney two warps.
[curing mainly] tonifying deficiency, beneficial vital essence, relieving cough and resolving phlegm, phlegm retention is breathed heavily and is coughed, and the dyspnea due to deficiency consumptive disease is coughed, spitting of blood, spontaneous sweating, impotence and seminal emission, soreness of waist and knee joint, prolonged deficiency is not multiple after being ill.
Herba Senecionis nudicaulis:
[nature,taste and action] sweet light cold.Heat-clearing and toxic substances removing moistens dryness and relieve cough, dissipating blood stasis for subsidence of swelling
[curing mainly usage] 1, exogenous high fever, the heatstroke fever; 2, cough due to lung-heat; 3, treating swelling and pain by traumatic injury.
Bombyx Batryticatus:
[nature and flavor] are hot salty, and are flat.1. " herbal classic ": salty in the mouth is flat.2. " not Lu ": suffering, flat, nontoxic.3. " property of medicine opinion ": tepor, slightly poisonous.
[return through] goes into liver, lung, stomach warp.1. " detailed outline ": the yin, yang of fainting is bright.2. " Thunder God is concocted the property of medicine and is separated ": go into the heart, liver, spleen, lung four warps.
[curing mainly] expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Control apoplectic aphasia, infantile convulsion, wind syndrome of head, acute throat trouble.Sore throat, scrofula tuberculosis.Wind skin ulcer urticaria, erysipelas, mastitis.1. " herbal classic ": main pediatric epilepsy scared night cry, go three worms, Mie Hei über, the cloudy infections disease of man.2. " not Lu ": woman's metrorrhagia be red white, puerperal surplus pain, all skin ulcer cicatrixs of going out.It does not seal furuncle and swells, and root ought go out certainly.3. " property of medicine opinion ": control locked mouth, diaphoresis, housewife people's metrorrhagia hematochezia is more than.4. " Japan hanako materia medica ": control apoplectic aphasia, and a wind cutting disease, convulsive seizure induced by terror in children, man's pudendal pruritus pain, woman's leukorrhagia.5. " Bencao Tujing ": control apoplexy, acute inflammation of the throat is smash the sieve smalls, the filling of Rhizoma Zingiberis Recens nature juice accent.6. " medicine origin ": all wind between the peeling skin.7. " detailed outline ": the wind-phlegm tuberculosis of loosing, scrofula, wind syndrome of head, wind worm toothache, skin wind skin ulcer, erysipelas is had an itch, intermittent fever due to phlegm crux, married woman's galactostasis, metrorrhagia hematochezia, children's's infantile malnutrition erosion squama body, all incised wounds, the furuncle wind hemorrhoid that swell.8. " book on Chinese herbal medicine just ": control the erosion of children's's infantile malnutrition, ulcer of gums, congenital deformity of the tongue, swollen and rigid tongue.9. " beautiful Chinese catalpa medicine is separated ": active stimulating the menstrual flow, wind dispelling is opened numbness.Control the headache thoracic obstruction, locked mouth is had a toothache, urticaria wind scabies; Burning is ground the wine clothes, and the stranguria with blood metrorrhagia is controlled on the broken top of the carbuncle of bursting again.
Herba Peperomiae Dindygulensis:
[meridian distribution of property and flavor]: sweet, suffering, cold.1. " choosing of Yunnan Chinese herbal medicine ": " hot light, flat." 2. " choosing of Simao, Yunnan Chinese herbal medicine ": " cool in nature, lightly seasoned." go into lung, spleen, liver, kidney channel
[effect]: clearing heat and moistening lung, invigorating the spleen and replenishing QI.
[curing mainly]: control carbuncle furuncle, edema, traumatic injury, asthma, tuberculosis.
Sargassum:
[nature and flavor with return through] are bitter, salty, and are cold.Return liver, stomach, kidney channel.
[function with cure mainly] hard masses softening and resolving, expectorant, diuretic.Be used for goiter, scrofula, painful and swollen testis, phlegm retention edema.
Lac regis apis:
[nature and flavor] sweet acid, flat.
[function cures mainly] nourishing, strong, the liver benefiting, spleen invigorating.Weak after curing the disease, infantile malnutrition, old asthenia, infectious hepatitis, hypertension, rheumatic arthritis, duodenal ulcer.
Moschus:
[meridian distribution of property and flavor] acrid in the mouth, temperature.GUIXIN, spleen channel.
[function cures mainly] refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain.Be used for the calentura coma, the apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, the attacked by pestiferous factors stupor, amenorrhea ， WEIJIA, the difficult labour stillborn fetus, trusted subordinate's sudden pain, the carbuncle scrofula, laryngopharynx swelling and pain falls and pounces on the pain of injury, the arthralgia pain numbness.
A kind of composition of medicine for the treatment of gastric and intestinal cancer of the present invention is to be formed by following weight parts raw material of Chinese medicine compatibility:
Fructus Arctii 6-12 part, white turnip 6-12 part, Radix Dauci Sativae 6-12 part, Germinatus Phragmitis 6-12 part, Aspongopus 6-12 part, Herba Hedyotidis Diffusae 4-9 part, Folium Raphani 4-9 part, Folium Dauci Sativae 4-9 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 4-9 part, Rhizoma Dioscoreae Bulbiferae 3-8 part, Herba Lobeliae Chinensis 3-8 part, Rhizoma Cimicifugae 3-8 part, wild cordyceps 3-8 part, Herba Senecionis nudicaulis 1-5 part, Bombyx Batryticatus 1-5 part, Herba Peperomiae Dindygulensis 1-5 part, Sargassum 1-5 part, Lac regis apis 1-5 part, Moschus 1-5 part;
Preparation method:
(1) plant extraction liquid: Fructus Arctii, white turnip, Radix Dauci Sativae, Germinatus Phragmitis, leaf of white turnip, Folium Dauci Sativae screening, clean adding distil water were soaked 2 hours according to formula proportion, wear into pasty state with fiberizer, add Lac regis apis and be heated to and boil 10-20 minute, being filtered to room temperature, to make plant extraction liquid standby;
(2) according to formula proportion with in Herba Hedyotidis Diffusae, Rhizoma Dioscoreae Bulbiferae, Herba Lobeliae Chinensis, Rhizoma Cimicifugae, Herba Peperomiae Dindygulensis, Herba Senecionis nudicaulis, wild cordyceps, 2 times of water gagings of immersion 40-60 minute, decocted 1-2 hour, 1 times of water gaging of medicinal residues adding was fried in shallow oil 15 minutes after the filtrate, the filtrate waste, the plant extraction liquid of twice filtrate and preparation method 1 merged decoct, be concentrated into the dry grinding of thick paste after bake to 300-400 order fine powder;
(3) press formula proportion with Aspongopus, Hericium erinaceus (Bull. Ex Fr.) Pers., Bombyx Batryticatus, Sargassum, Lac regis apis, Moschus screening, putting into pressure cooker steamed 20-40 minute in 150-180 ℃, be cooled to room temperature, spread covering to place under the sunlight with black cloth on the bamboo mat and dry, it is standby to be ground into 300-400 purpose fine powder;
(4), with the fine powder mix homogeneously that preparation method 2,3 obtains, seal after 72 hours divide encapsulated.
Instructions of taking: take with warm water half an hour ante cibum, takes 15g every day three times at every turn, warm water delivery service, and one month is a course of treatment, cure 2-3 the course of treatment.The avoid cold and uncooked food thing of pungent stimulation.
Consumption: 1 a, course of treatment (12 days); 2, general gastrointestinal disease one to two course of treatment; 3, three of serious gastrointestinal diseasies are more than the course of treatment; 4, five of human primary gastrointestinal cancers, the esophageal carcinoma, esophageal carcinoma patients that esophagitis, esophagitis three courses of treatment are above 5, pathological changes appears in gastrointestinal are more than the course of treatment; 6, above patient serve on two to six boxes and effect or alleviating pain can occur.
A kind of composition of medicine for the treatment of gastric and intestinal cancer of the present invention is to be formed by following weight parts raw material of Chinese medicine compatibility:
Fructus Arctii 8-10 part, white turnip 8-10 part, Radix Dauci Sativae 8-10 part, Germinatus Phragmitis 8-10 part, Aspongopus 8-10 part, Herba Hedyotidis Diffusae 6-8 part, Folium Raphani 6-8 part, Folium Dauci Sativae 6-8 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 6-8 part, Rhizoma Dioscoreae Bulbiferae 4-7 part, Herba Lobeliae Chinensis 4-7 part, Rhizoma Cimicifugae 4-7 part, wild cordyceps 4-7 part, Herba Senecionis nudicaulis 2-4 part, Bombyx Batryticatus 2-4 part, Herba Peperomiae Dindygulensis 2-4 part, Sargassum 2-4 part, Lac regis apis 2-4 part, Moschus 2-4 part.
A kind of composition of medicine for the treatment of gastric and intestinal cancer of the present invention is to be formed by following weight parts raw material of Chinese medicine compatibility:
9 parts of Fructus Arctiis, 9 parts of white turnips, 9 parts in Radix Dauci Sativae, 9 parts of Germinatus Phragmitiss, 9 parts of Aspongopuss, 7 parts of Herba Hedyotidis Diffusaes, 7 parts of Folium Raphani, 7 parts of Folium Dauci Sativaes, 7 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 5 parts of Rhizoma Dioscoreae Bulbiferaes, 5 parts of Herba Lobeliae Chinensis, 5 parts of Rhizoma Cimicifugaes, 5 parts of wild cordyceps, 3 parts of Herba Senecionis nudicauliss, 3 parts of Bombyx Batryticatus, 3 parts of Herba Peperomiae Dindygulensiss, 3 parts of Sargassums, 3 parts of Lac regis apis, 3 parts in Moschus.
The specific embodiment:
Embodiment 1:
Prescription: Fructus Arctii 6g, white turnip 6g, Radix Dauci Sativae 6g, Germinatus Phragmitis 6g, Aspongopus 6g, Herba Hedyotidis Diffusae 4g, Folium Raphani 4g, Folium Dauci Sativae 4g, Hericium erinaceus (Bull. Ex Fr.) Pers. 4g, Rhizoma Dioscoreae Bulbiferae 3g, Herba Lobeliae Chinensis 3g, Rhizoma Cimicifugae 3g, wild cordyceps 3g, Herba Senecionis nudicaulis 1g, Bombyx Batryticatus 1g, Herba Peperomiae Dindygulensis 1g, Sargassum 1g, Lac regis apis 1g, Moschus 1g;
Preparation method:
(1) plant extraction liquid: Fructus Arctii, white turnip, Radix Dauci Sativae, Germinatus Phragmitis, leaf of white turnip, Folium Dauci Sativae screening, clean adding distil water were soaked 2 hours according to formula proportion, wear into pasty state with fiberizer, add Lac regis apis and be heated to and boil 10-20 minute, being filtered to room temperature, to make plant extraction liquid standby;
(2) according to formula proportion with in Herba Hedyotidis Diffusae, Rhizoma Dioscoreae Bulbiferae, Herba Lobeliae Chinensis, Rhizoma Cimicifugae, Herba Peperomiae Dindygulensis, Herba Senecionis nudicaulis, wild cordyceps, 2 times of water gagings of immersion 40-60 minute, decocted 1-2 hour, 1 times of water gaging of medicinal residues adding was fried in shallow oil 15 minutes after the filtrate, the filtrate waste, the plant extraction liquid of twice filtrate and preparation method 1 merged decoct, be concentrated into the dry grinding of thick paste after bake to 300-400 order fine powder;
(3) press formula proportion with Aspongopus, Hericium erinaceus (Bull. Ex Fr.) Pers., Bombyx Batryticatus, Sargassum, Lac regis apis, Moschus screening, putting into pressure cooker steamed 20-40 minute in 150-180 ℃, be cooled to room temperature, spread covering to place under the sunlight with black cloth on the bamboo mat and dry, it is standby to be ground into 300-400 purpose fine powder;
(4), with the fine powder mix homogeneously that preparation method 2,3 obtains, seal after 72 hours divide encapsulated.
Instructions of taking: take with warm water half an hour ante cibum, takes 15g every day three times at every turn, warm water delivery service, and one month is a course of treatment, cure 2-3 the course of treatment.The avoid cold and uncooked food thing of pungent stimulation.
Consumption: 1 a, course of treatment (12 days); 2, general gastrointestinal disease one to two course of treatment; 3, three of serious gastrointestinal diseasies are more than the course of treatment; 4, five of human primary gastrointestinal cancers, the esophageal carcinoma, esophageal carcinoma patients that esophagitis, esophagitis three courses of treatment are above 5, pathological changes appears in gastrointestinal are more than the course of treatment; 6, above patient serve on two to six boxes and effect or alleviating pain can occur.
Embodiment 2:
Prescription: Fructus Arctii 8g, white turnip 8g, Radix Dauci Sativae 8g, Germinatus Phragmitis 8g, Aspongopus 8g, Herba Hedyotidis Diffusae 6g, Folium Raphani 6g, Folium Dauci Sativae 6g, Hericium erinaceus (Bull. Ex Fr.) Pers. 6g, Rhizoma Dioscoreae Bulbiferae 4g, Herba Lobeliae Chinensis 4g, Rhizoma Cimicifugae 4g, wild cordyceps 4g, Herba Senecionis nudicaulis 2g, Bombyx Batryticatus 2g, Herba Peperomiae Dindygulensis 2g, Sargassum 2g, Lac regis apis 2g, Moschus 2g;
Preparation method is identical with embodiment 1 with usage and dosage.
Embodiment 3:
Prescription: Fructus Arctii 9g, white turnip 9g, Radix Dauci Sativae 9g, Germinatus Phragmitis 9g, Aspongopus 9g, Herba Hedyotidis Diffusae 7g, Folium Raphani 7g, Folium Dauci Sativae 7g, Hericium erinaceus (Bull. Ex Fr.) Pers. 7g, Rhizoma Dioscoreae Bulbiferae 5g, Herba Lobeliae Chinensis 5g, Rhizoma Cimicifugae 5g, wild cordyceps 5g, Herba Senecionis nudicaulis 3g, Bombyx Batryticatus 3g, Herba Peperomiae Dindygulensis 3g, Sargassum 3g, Lac regis apis 3g, Moschus 3g;
Preparation method is identical with embodiment 1 with usage and dosage.
Embodiment 4:
Prescription: Fructus Arctii 10g, white turnip 10g, Radix Dauci Sativae 10g, Germinatus Phragmitis 10g, Aspongopus 10g, Herba Hedyotidis Diffusae 8g, Folium Raphani 8g, Folium Dauci Sativae 8g, Hericium erinaceus (Bull. Ex Fr.) Pers. 8g, Rhizoma Dioscoreae Bulbiferae 7g, Herba Lobeliae Chinensis 7g, Rhizoma Cimicifugae 7g, wild cordyceps 7g, Herba Senecionis nudicaulis 4g, Bombyx Batryticatus 4g, Herba Peperomiae Dindygulensis 4g, Sargassum 4g, Lac regis apis 4g, Moschus 4g;
Preparation method is identical with embodiment 1 with usage and dosage.
Embodiment 5:
Prescription: Fructus Arctii 12g, white turnip 12g, Radix Dauci Sativae 12g, Germinatus Phragmitis 12g, Aspongopus 12g, Herba Hedyotidis Diffusae 9g, Folium Raphani 9g, Folium Dauci Sativae 9g, Hericium erinaceus (Bull. Ex Fr.) Pers. 9g, Rhizoma Dioscoreae Bulbiferae 8g, Herba Lobeliae Chinensis 8g, Rhizoma Cimicifugae 8g, wild cordyceps 8g, Herba Senecionis nudicaulis 5g, Bombyx Batryticatus 5g, Herba Peperomiae Dindygulensis 5g, Sargassum 5g, Lac regis apis 5g, Moschus 5g;
Preparation method is identical with embodiment 1 with usage and dosage.
The clinical experiment that Chinese medicine preparation of the present invention is carried out below:
A kind of composition of medicine for the treatment of gastric and intestinal cancer, its therapeutic effect 1-2 week produce effects, gastric acid, stomachache obviously alleviate, and after 30-50 days positive effect are arranged, effective percentage 90%, life-saving rate 80%.
Clinical experiment amounted to for five phases, and the test first phase is finished needs four months the full course of treatment.
It all is the case of making a definite diagnosis through checking that case is selected, and also is the middle and terminal cancer patient simultaneously.
Clinical trial number 1050 people, male 750 people, women 300 people, the oldest 81 years old, minimum 38 years old, 60 years old mean age, total effective rate 90%.
Efficient Time Calculation, effectively, generating 1-2 is that effectively generation 2-5 is a produce effects, recovery from illness, cancerous cell disappears entirely on inspection, and it is normal that every index is recovered, and is recovery from illness.
Model case:
Case 1:
Open XX, man 68 years old, the gastric cancer middle and advanced stage behind the excision, finds in the art that the intraperitoneal lymph node extensively shifts, postoperative is taken 6 courses of treatment of Chinese medicinal capsule of the present invention, follows up a case by regular visits to 3 years, recurrence.
Case 2:
Cui XX, man 43 years old takes 3 courses of treatment of Chinese medicinal capsule of the present invention at gastric cancer late period, and tumor tissues dwindles gradually, treat 5 courses of treatment, and tumor tissues disappears, and follows up a case by regular visits to not recur in 3 years.
Case 3:
Liu XX, woman 66 years old, in 05 year gastric cancer late period, excision finds in the art that mediastinum and aorta shift, postoperative is taken 5 courses of treatment of capsule of the present invention, follows up a case by regular visits to, so far recurrence.
Case 4:
Lee XX, man 55 years old, in 03 year gastric cancer late period, excision finds in the art that extensive lymphonodi coeliaci shifts, postoperative is taken 5 courses of treatment of capsule of the present invention, follows up a case by regular visits to, so far recurrence.
Case 5:
Open XX, woman 75 years old, 03 year gastric cancer middle and advanced stage, the row excision is found in the art to shift behind the peritoneum, and postoperative is taken 6 courses of treatment of capsule of the present invention, follows up a case by regular visits to, so far recurrence.
Case 6:
Open XX, man 77 years old takes 3 courses of treatment of capsule of the present invention at gastric cancer late period, and tumor tissues dwindles gradually, treat 5 courses of treatment, and tumor tissues fades away, and follows up a case by regular visits to 3 years, recurs.
Case 7:
Permitted XX, woman 68 years old, 07 year gastric cancer middle and advanced stage behind the excision, finds in the art that the intraperitoneal lymph node extensively shifts, postoperative is taken 5 courses of treatment of Chinese medicinal capsule of the present invention, follows up a case by regular visits to 3 years, recurrence.
Case 8:
Xing XX, woman 55 years old takes 2 courses of treatment of Chinese medicinal capsule of the present invention in 05 year gastric cancer late period, and tumor tissues dwindles gradually, treat 6 courses of treatment, and tumor tissues disappears, and follows up a case by regular visits to so far to recur.
Case 9:
Cao XX, woman 45 years old, in 07 year gastric cancer late period, excision finds in the art that mediastinum and aorta shift, postoperative is taken 6 courses of treatment of capsule of the present invention, follows up a case by regular visits to, so far recurrence.
Case 10:
Sieve XX, man 56 years old, in 06 year gastric cancer late period, excision finds in the art that extensive lymphonodi coeliaci shifts, postoperative is taken 6 courses of treatment of capsule of the present invention, follows up a case by regular visits to, so far recurrence.
Case 11:
Open XX, man 75 years old, 08 year gastric cancer middle and advanced stage, the row excision is found in the art to shift behind the peritoneum, and postoperative is taken 6 courses of treatment of capsule of the present invention, follows up a case by regular visits to, so far recurrence.
Claims (3)
1. a composition of medicine for the treatment of gastric and intestinal cancer is characterized in that, is to be formed by following weight parts raw material of Chinese medicine compatibility:
Fructus Arctii 6-12 part, white turnip 6-12 part, Radix Dauci Sativae 6-12 part, Germinatus Phragmitis 6-12 part, Aspongopus 6-12 part, Herba Hedyotidis Diffusae 4-9 part, Folium Raphani 4-9 part, Folium Dauci Sativae 4-9 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 4-9 part, Rhizoma Dioscoreae Bulbiferae 3-8 part, Herba Lobeliae Chinensis 3-8 part, Rhizoma Cimicifugae 3-8 part, wild cordyceps 3-8 part, Herba Senecionis nudicaulis 1-5 part, Bombyx Batryticatus 1-5 part, Herba Peperomiae Dindygulensis 1-5 part, Sargassum 1-5 part, Lac regis apis 1-5 part, Moschus 1-5 part;
Preparation method:
(1) plant extraction liquid: Fructus Arctii, white turnip, Radix Dauci Sativae, Germinatus Phragmitis, leaf of white turnip, Folium Dauci Sativae screening, clean adding distil water were soaked 2 hours according to formula proportion, wear into pasty state with fiberizer, add Lac regis apis and be heated to and boil 10-20 minute, being filtered to room temperature, to make plant extraction liquid standby;
(2) according to formula proportion with in Herba Hedyotidis Diffusae, Rhizoma Dioscoreae Bulbiferae, Herba Lobeliae Chinensis, Rhizoma Cimicifugae, Herba Peperomiae Dindygulensis, Herba Senecionis nudicaulis, wild cordyceps, 2 times of water gagings of immersion 40-60 minute, decocted 1-2 hour, 1 times of water gaging of medicinal residues adding was fried in shallow oil 15 minutes after the filtrate, the filtrate waste, the plant extraction liquid of twice filtrate and preparation method 1 merged decoct, be concentrated into the dry grinding of thick paste after bake to 300-400 order fine powder;
(3) press formula proportion with Aspongopus, Hericium erinaceus (Bull. Ex Fr.) Pers., Bombyx Batryticatus, Sargassum, Moschus screening, putting into pressure cooker steamed 20-40 minute in 150-180 ℃, be cooled to room temperature, spread covering to place under the sunlight with black cloth on the bamboo mat and dry, it is standby to be ground into 300-400 purpose fine powder;
(4), with the fine powder mix homogeneously that preparation method 2,3 obtains, seal after 72 hours divide encapsulated.
2. a kind of composition of medicine for the treatment of gastric and intestinal cancer according to claim 1 is characterized in that, is to be formed by following weight parts raw material of Chinese medicine compatibility:
Fructus Arctii 8-10 part, white turnip 8-10 part, Radix Dauci Sativae 8-10 part, Germinatus Phragmitis 8-10 part, Aspongopus 8-10 part, Herba Hedyotidis Diffusae 6-8 part, Folium Raphani 6-8 part, Folium Dauci Sativae 6-8 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 6-8 part, Rhizoma Dioscoreae Bulbiferae 4-7 part, Herba Lobeliae Chinensis 4-7 part, Rhizoma Cimicifugae 4-7 part, wild cordyceps 4-7 part, Herba Senecionis nudicaulis 2-4 part, Bombyx Batryticatus 2-4 part, Herba Peperomiae Dindygulensis 2-4 part, Sargassum 2-4 part, Lac regis apis 2-4 part, Moschus 2-4 part.
3. a kind of composition of medicine for the treatment of gastric and intestinal cancer according to claim 1, its feature also are, are to be formed by following weight parts raw material of Chinese medicine compatibility:
9 parts of Fructus Arctiis, 9 parts of white turnips, 9 parts in Radix Dauci Sativae, 9 parts of Germinatus Phragmitiss, 9 parts of Aspongopuss, 7 parts of Herba Hedyotidis Diffusaes, 7 parts of Folium Raphani, 7 parts of Folium Dauci Sativaes, 7 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 5 parts of Rhizoma Dioscoreae Bulbiferaes, 5 parts of Herba Lobeliae Chinensis, 5 parts of Rhizoma Cimicifugaes, 5 parts of wild cordyceps, 3 parts of Herba Senecionis nudicauliss, 3 parts of Bombyx Batryticatus, 3 parts of Herba Peperomiae Dindygulensiss, 3 parts of Sargassums, 3 parts of Lac regis apis, 3 parts in Moschus.
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| CN115472241B (en) * | 2022-09-23 | 2023-07-14 | 湖南中医药大学 | Chinese medicine component cluster menstruation determining method based on chemical structure topology index comparison and chromatographic imprinting measurement |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1090964C (en) * | 1999-12-09 | 2002-09-18 | 殷增航 | Powder medicine 'Zhuyushengxin San' for treating stasis |
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Non-Patent Citations (1)
| Title |
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| 芦峰等.中药癌痛克的实验研究与临床研究.《中国肿瘤》.2004,第13卷(第5期),第325-327页. * |
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