CN103735997B - A kind of Chinese medicine preparation and preparation method for the treatment of gastric cancer - Google Patents
A kind of Chinese medicine preparation and preparation method for the treatment of gastric cancer Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine preparation and preparation method for the treatment of gastric cancer, belong to the field of Chinese medicines; The raw material of Chinese medicine preparation effective ingredient of the present invention consists of: Fomes Fomentarius, Radix Polemonii Liniflori, Herba Ardisiae Maculosae, Bulbus Fritillariae Uninbracteatae, Cortex Linderae Fragrantis, Fructus Chebulae, the Fructus Evodiae, Fructus Psoraleae, Zi Pao, Radix Stephaniae Cepharanthae, Rhizoma Atractylodis, Maifanitum, Fructus rosae multiflorae, Fructus Aristolochiae Kwangsiensis, Herba Aristolochiae and Fructus Amomi Rotundus; The selected high-quality medical material of Chinese medicine preparation of the present invention is made, there is effect of eliminating dampness and expelling toxin, promoting the circulation of QI to relieve pain, eliminating stagnation blood stasis dispelling, cancerous tumor cell can be broken up, repair damaged tissues, improve body's immunity, can be applicable to the treatment of gastric cancer and the postoperative auxiliary treatment of cancer, evident in efficacy, safe without toxic side effect, selected medical material compatibility meets Chinese crude drug and modern medicine and pharmacology research is theoretical, can reach the object for the treatment of both the principal and secondary aspects of a disease.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and preparation method for the treatment of gastric cancer.
Background technology
Gastric cancer is one of modal malignant tumor of China, and mortality rate is high, every 4 because just there being 1 routine patients with gastric cancer in the patient of mortality of malignant tumors, therefore gastric cancer is the disease of serious harm our people life and health.Early gastric cancer after treatment more than 90% patient can be more than 5-year Survival, and late gastric cancer patient, the probability of 5-year Survival is less than 5%, the high-risk group of so-called gastric cancer, just refer to the people that get a cancer of the stomach easier than common people, their incidence gastric cancer rate than high several times of general population, even nearly 10 times.Gastric cancer ranks first in the various malignant tumor of China, and incidence gastric cancer has obvious region difference, is evident as height in the northwest of China and coastal region in east China incidence gastric cancer rate than southern area, sends out well the age more than 50 years old, and the ratio of men and women's sickness rate is 2:1.
The most patient's non-evident sympton of early gastric cancer, a few peoples have the digestive symptoms of Nausea and vomiting or similar Peptic Ulcers, and pain is the modal clinical symptoms of advanced gastric carcinoma with losing weight.At present, the Therapeutic Method of gastric cancer mainly contains: one is operative treatment, and operation no doubt can excise cancerous protuberance, but to also have in residual cancer or regional lymph node metastasis or blood vessel cancer embolus existence etc., relapse and metastasis probability is very high, and two is radiotherapies, radiation complication is more, even causes partial loss of function; For late tumor patient, the effect of radiation therapy is not intact.Body constitution is poor simultaneously, older patient, and it is more critically ill that continuation radiotherapy can only lead debilitant life, accelerates death; Three is chemotherapies, and chemotherapy is Therapeutic Method progressive the fastest in oncotherapy in recent years, but chemotherapeutics normal " right and wrong are unclear ", " failing to differentiate between the enemy and ourselves ", while killing tumor cell, also kill and wound human normal cell; Four is treatments by Chinese herbs, and the technology of the treatment by Chinese herbs cancer now announced also exists some problems needing to solve, but Chinese traditional treatment has the irreplaceable advantage of other Therapeutic Method, has research and extension widely and is worth.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of gastric cancer; The selected high-quality medical material of Chinese medicine preparation of the present invention is made, there is effect of eliminating dampness and expelling toxin, promoting the circulation of QI to relieve pain, eliminating stagnation blood stasis dispelling, cancerous tumor cell can be broken up, repair damaged tissues, improve body's immunity, can be applicable to the treatment of gastric cancer and the postoperative auxiliary treatment of cancer, evident in efficacy, safe without toxic side effect, selected medical material compatibility meets Chinese crude drug and modern medicine and pharmacology research is theoretical, can reach the object for the treatment of both the principal and secondary aspects of a disease.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for gastric cancer, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of gastric cancer, comprise following processing step:
(1) Fomes Fomentarius, Radix Polemonii Liniflori, Cortex Linderae Fragrantis, Zi Pao, Radix Stephaniae Cepharanthae and Fructus rosae multiflorae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, for subsequent use;
(2) Herba Ardisiae Maculosae, Fructus Chebulae, the Fructus Evodiae, Fructus Psoraleae and Fructus Amomi Rotundus are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 70% of 3 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.10 ~ 1.12, for subsequent use;
(3) Herba Aristolochiae and Rhizoma Atractylodis decontamination are cleaned, dry, put into pot, slow fire is fried to surface in coke yellow, and taking-up is dried in the air cool, grinds into powder, crosses 180 order fine powders, for subsequent use;
(4) by Bulbus Fritillariae Uninbracteatae, Maifanitum and Fructus Aristolochiae Kwangsiensis decontamination respectively, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(5) by the filtrate obtained by above-mentioned steps (1) ~ (4), thick paste and fine powder mixing, make tablet, obtain the Chinese medicine preparation for the treatment of gastric cancer of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Fomes Fomentarius: mildly bitter flavor, property is put down.Removing food stagnancy, blood stasis dispelling, anticancer.Cure mainly food stagnation, the esophageal carcinoma, gastric cancer, uterus carcinoma.Pharmacological evaluation shows, Fomes Fomentarius can significantly improve the tolerance of experiment mice hypobaric hypoxia, extends its time-to-live, has the effect of resisting fatigue, high temperature resistance, and can affect flow velocity, the fluidised form of anoxia body Mesentery microcirculation, has improvement result to microcirculation.
Radix Polemonii Liniflori: bitter in the mouth, property is put down; Return lung, the heart, liver, spleen, stomach warp.Reduce phlegm, calm the nerves, hemostasis.Cure mainly cough with copious phlegm, epilepsy, insomnia, spitting of blood, nosebleed is bent, spits blood, has blood in stool, menorrhagia." Jilin Chinese herbal medicine " carries: " eliminate the phlegm, hemostasis, calm.Control abundant expectoration cough, epilepsy is had a sleepless night, menorrhagia.”
Herba Ardisiae Maculosae: bitter in the mouth, property is flat, tepor; Return liver, kidney, lung meridian.Promoting blood circulation and stopping pain, clearing throat.Cure mainly traumatic injury, fracture, rheumatic arthralgia, diphtheria, laryngopharynx swelling and pain, gastric ulcer.
Bulbus Fritillariae Uninbracteatae: bitter in the mouth, sweet, cold nature; Return lung, heart channel.Clearing heat and moistening lung, preventing phlegm from forming and stopping coughing.For cough due to lung-heat, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood." Bencao Jingshu " carries: " cold-damp expectorant and food stagnation phlegm-fire are coughed, and damp-phlegm to be felt sick tending to vomit at stomach, and phlegm retention makes cold and heat, and taste damp-phlegm does dizzy and syncope due to accumulation of phlegm headache, and attacked by pestiferous factors vomiting, cold syndrome of the stomach is let out and forbidden.”
Cortex Linderae Fragrantis: acrid in the mouth, warm in nature; Return stomach warp.Warming middle-JIAO to promote flow of QI, expelling wind and cold.Cure mainly anemofrigid cold, gastralgia, dyspepsia, rheumatic arthralgia." Hunan folk medicine data " carries: " pleasant; Control gastropathy, gastric ulcer, dyspepsia.”
Fructus Chebulae: sour in the mouth, puckery, property is put down.To astringe the lung astringing intestine to stop diarrhea, therapeutic method to keep the adverse QI flowing downwards sore-throat relieving.Cure mainly chronic diarrhea, chronic dysentery, proctoptosis, phlegmatic cough of breathing with cough, chronic cough aphonia." Japan hanako materia medica " carries: " relieving restlessness, harnesses the river for expectorant, the therapeutic method to keep the adverse QI flowing downwards, and in tune, antidiarrheal dysentery, cholera, renal mass kidney qi, lung qi dyspnea with rapid respiration, digesting and appetizing, hemorrhoidal hamorrhage rushes down blood, metrorrhagia leukorrhagia, five types of dysphagia.”
The Fructus Evodiae: sour in the mouth, puckery, slightly warm in nature; Enter liver, stomach warp.Invigorating the liver and kidney, arresting seminal emission gas, Gu collapse, stomach invigorating tonifying YANG.Treatment soreness of waist and knee joint, dizzy, tinnitus, seminal emission, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart shakes scattered pulse, neurasthenia, the diseases such as menoxenia.Modern medicine study confirms, the Fructus Evodiae can suppress dysentery bacterium, Bacillus typhi, golden yellow puckery staphylococcus and some dermatophytes, has diuresis, blood pressure lowering, protective effect on cancer risk.
Fructus Psoraleae: acrid in the mouth, hardship, warm in nature; Return kidney, the heart, spleen, stomach, lung meridian.Reinforcing the kidney and supporting YANG, helping inspiration to relieve asthma, warming spleen and stopping diarrha.Cure mainly insufficiency of kidney-YANG, below element deficiency and cold, chills and pain of the waist and kness, sexual impotence essence, frequent micturition, the enuresis, failure of the kidney in receiving QI, dyspnea due to deficiency is more than, asthenia of both the spleen and kidney, stool chronic diarrhea, vitiligo, alopecia areata, psoriasis." beautiful Chinese catalpa medicine solution " carry: " warm water and soil, digestion diet, rise reach taste, convergence lingering diarrhea, seminal emission, leukorrhagia, drown many, just slide all cards.”
Purple bubble: bitter in the mouth, puckery, sweet, sour, property is flat, tepor.Antidiarrheal dysentery, wind-expelling pain-stopping, clearing away heat-damp and promoting diuresis, antiinflammatory, the kidney invigorating arresting seminal emission.Cure mainly dysentery, diarrhoea, rheumatic arthritis, gout, acute hepatitis, chronic hepatitis, menoxenia, infantile malnutrition, dampen pain, eczema, skin purulent infection, stomatitis, angina, gingivitis, urinary stone, neurasthenia, seminal emission, premature ejaculation.
Radix Stephaniae Cepharanthae: bitter in the mouth, cold in nature; Enter spleen, lung, kidney channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis, dissipating blood stasis for subsidence of swelling.For acute hepatitis, bacillary dysentery, acute appendicitis, stomachache, internal hemorrhage, traumatic injury, venom; Mumps is controlled in external, lymphadenitis, neurodermatitis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " dispel the wind, diuretic, heat clearing away, reduces phlegm.Dispelling the wind and dampness pathogens pain, lumbar muscle strain, oedema due to nephritis, stomachache, pulmonary tuberculosis, innominate toxic swelling, venom.”
Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature; Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia." Bencao Jingshu " carries: " all diseases belong to deficiency of YIN insufficiency of blood, insufficiency of essence, interior-heat hectic fever due to YIN-deficiency, dry mouth with parched lips, and cough is spat, spitted blood, and epistaxis, obstruction of the pharynx, constipation dysentery person, method is salty avoids it.Liver and kidney has the person of taking offence not take.”
Maifanitum: sweet in the mouth, warm in nature, nontoxic; Return liver, stomach, kidney channel.Detoxicating and resolving stagnation of pathogens, removing the necrotic tissue and promoting granulation, except cold damp eliminating, the liver benefiting stomach invigorating, blood circulation promoting and blood stasis dispelling, diuresis fossil, life lengthening.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.
Fructus rosae multiflorae: sour in the mouth, cool in nature; Return lung, spleen, liver, urinary bladder channel.Diuretic heat extraction, promoting blood circulation and detoxication.Cure mainly edema, beriberi, sore carbuncle, dysuria, abdominal pain in menstruation." modern Practical Chinese medicinal " carries: " except rheumatism.The dermatosiss such as edema, menoxenia, dysuria, beriberi generalized edema with distention of the chest and abdomen, syphilitic skin lesions incrustation, tinea skin ulcer are caused to generalized edema with distention of the chest and abdomen is breathed with cough, constipation and anuresis, person is effective with this for trusted subordinate's feeling of distension and oppression.”
Fructus Aristolochiae Kwangsiensis: bitter in the mouth, cold in nature; Return stomach warp.Heat-clearing and toxic substances removing, regulating QI to relieve pain, relaxing muscles and tendons and activating QI and blood in the collateral.For acute gastroenteritis, taste-blindness rate, pharyngolaryngitis, pulmonary tuberculosis, main ulcer sore pain, stomachache, abdominalgia with intestinal abscess, rheumatic arthralgia, treating swelling and pain by traumatic injury." register planted by Guangxi medicine " carries: " refrigerantly to bring down a fever, removing toxic substances.Control dizziness, laryngalgia, gastropathy, stomachache, skin ulcer scabies, knife injury, snakebite.”
Herba Aristolochiae: circulation of qi promoting removing dampness, promoting blood circulation and stopping pain.Cure mainly stomachache, colicky, edema during pregnancy, puerperal, vim and vigour were suffered from abdominal pain, rheumatalgia.Promoting flow of QI and blood, pain relieving, diuresis, edema during pregnancy, breast is suffered from abdominal pain, colic, rheumatalgia." book on Chinese herbal medicine is new again " carries: " removing heat from blood and promoting blood circulation, removes wind dampness removing, walk meridians, doublely controls the swollen pain of waist lower limb.”
Fructus Amomi Rotundus: acrid in the mouth, hot in nature; Return lung meridian, spleen channel, stomach warp.Cold expelling dampness, alcoholic intoxication, removing dampness disappears painful abdominal mass, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving.For turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, uncomfortable in chest not hungry, cold-damp vomiting, chest and abdomen swelling and pain, food stagnation does not disappear." book on Chinese herbal medicine is original " carries: " tonifying the spleen and stomach, mill is stagnant, and adjust cold scattering gas very fast, it is the most suitable that weakness can not drink trencherman, alcoholic intoxication of holding concurrently.”
The present invention compared with prior art, has following beneficial effect:
The selected high-quality medical material of Chinese medicine preparation of the present invention is made, there is effect of eliminating dampness and expelling toxin, promoting the circulation of QI to relieve pain, eliminating stagnation blood stasis dispelling, cancerous tumor cell can be broken up, repair damaged tissues, improve body's immunity, can be applicable to the treatment of gastric cancer and the postoperative auxiliary treatment of cancer, evident in efficacy, safe without toxic side effect, selected medical material compatibility meets Chinese crude drug and modern medicine and pharmacology research is theoretical, can reach the object for the treatment of both the principal and secondary aspects of a disease.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Treat a preparation method for the Chinese medicine preparation of gastric cancer, comprise following processing step:
(1) Fomes Fomentarius, Radix Polemonii Liniflori, Cortex Linderae Fragrantis, Zi Pao, Radix Stephaniae Cepharanthae and Fructus rosae multiflorae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, for subsequent use;
(2) Herba Ardisiae Maculosae, Fructus Chebulae, the Fructus Evodiae, Fructus Psoraleae and Fructus Amomi Rotundus are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 70% of 3 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.10 ~ 1.12, for subsequent use;
(3) Herba Aristolochiae and Rhizoma Atractylodis decontamination are cleaned, dry, put into pot, slow fire is fried to surface in coke yellow, and taking-up is dried in the air cool, grinds into powder, crosses 180 order fine powders, for subsequent use;
(4) by Bulbus Fritillariae Uninbracteatae, Maifanitum and Fructus Aristolochiae Kwangsiensis decontamination respectively, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(5) by the filtrate obtained by above-mentioned steps (1) ~ (4), thick paste and fine powder mixing, make tablet, obtain the Chinese medicine preparation for the treatment of gastric cancer of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of and can fully recovering, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of gastric cancer, select the routine clinical observation of patients with gastric cancer 200 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 100 example, wherein male 58 example, women 42 example, 50 ~ 75 years old age, 62.3 years old mean age, the shortest person of the course of disease 3 months, most elder 2 years, average 1 year.Matched group 100 example, wherein male 57 example, women 43 example, 51 ~ 76 years old age, 61.3 years old mean age, the shortest person of the course of disease 4 months, most elder 3 years, average 2 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, take 2 ~ 3 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.。
Matched group takes the precious capsule of stilbene, oral, every day 3 times, each 5, uses warm water delivery service; Within 15 days, be 1 course for the treatment of, take 3 ~ 4 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: tumor stomach disappears, appetite takes a turn for the better, and muscle power strengthens, and spirit improves.
(2) effective: tumor stomach reduces, and pain obviously alleviates, appetite takes a turn for the better, and muscle power strengthens, and spirit improves.
(3) effective: tumor has no further diffusion and transfer, and tumor body is controlled, and pain and nausea and vomiting symptom alleviate.
(4) invalid: clinical symptoms is without obvious change.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 48 examples, effective 31 examples, effective 19 examples, invalid 2 examples, cure rate 48%, total effective rate 98%.
17 examples are cured, effective 24 examples, effective 21 examples, invalid 38 examples, cure rate 17%, total effective rate 62% in matched group.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, high certain, man, 53 years old, Yuncheng, Shanxi people.The glutted discomfort of patient's epigastrium or dull pain, occasionally have vomiting, loss of appetite, dyspeptic symptom, admission examination is diagnosed as early gastric cancer.Through many hospitalize DeGrains, rear to our hospital, take Chinese medicine preparation of the present invention, oral, every day 2 times, sooner or later each 1 time, each 2, after taking 1 course for the treatment of, symptom is alleviated to some extent, after taking 3 courses for the treatment of, transference cure is cured through examination in hospital, follows up a case by regular visits to, and does not recur so far.
2, certain is congratulated, female, 65 years old, From Shandong Rizhao people.Patient's epigastric discomfort has feeling of repletion, and local hospital presses gastric ulcer treatment, poor effect, gastroscopy is shown at once, and body of stomach rear wall swells swollen thing as seen, and size is about 3.0 × 4.0cm, the matter touched is hard, easily hemorrhage, get biopsy and show mucinous adenocarcinoma at the bottom of stomach, because there is melena, row CT examination is shown, coat of the stomach diffuse thickening, its interior visible strip calcification of part, is diagnosed as gastric cancer.Take Chinese medicine preparation of the present invention, after taking 1 course for the treatment of, subjective symptoms is significantly alleviated, and spiritual diet is comparatively front to take a turn for the better, and without edema of lower limbs, glutted discomfort alleviates to some extent, after taking 2 courses for the treatment of, and abdominal distention transference cure, tumor reduces; After continuing to take 1 course for the treatment of, the state of an illness does not occur repeatedly increasing the weight of situation.
3, relative, man, 72 years old, people from Dalian.Patient's epigastrium distending pain, with after meal, movable after, erect position time increase the weight of, sleep is had a strong impact on.Hospital gastroscope is observed and biopsy pathology is diagnosed as cancer at the bottom of cardia stomach.Exploratory laparotomy finds that tumor stomach is about 8cm × 10cm × 7cm size, fixes, and shifts towards periphery, fail to do any resection operation with pancreas adhesion.Take Chinese medicine preparation of the present invention, after taking 1 course for the treatment of, upper abdomen stomachache disappears, and after taking the 2nd course for the treatment of, CT examination focus shade diminishes, lightens, and after continuing to take 1 course for the treatment of, lives the same with normal person.
Claims (5)
1. treat a Chinese medicine preparation for gastric cancer, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fomes Fomentarius 37 ~ 67 Fen Radix Polemonii Liniflori 32 ~ 62 parts of Herba Ardisiae Maculosaes 32 ~ 57 portions of Bulbus Fritillariae Uninbracteataes 27 ~ 57 parts
Cortex Linderae Fragrantis 27 ~ 57 parts of Fructus Chebulaes 27 ~ 52 parts of Fructus Corni 22 ~ 52 parts of Fructus Psoraleaes 22 ~ 52 parts
Purple bubble 22 ~ 47 parts of Radix Stephaniae Cepharanthaes, 17 ~ 47 parts of Rhizoma Atractylodis 17 ~ 42 parts of Maifanitums 17 ~ 42 parts
7 ~ 32 parts, Fructus rosae multiflorae 17 ~ 47 parts of Fructus Aristolochiae Kwangsiensiss 12 ~ 42 parts of Herba Aristolochiaes 12 ~ 37 parts of Fructus Amomi Rotunduss.
2. a kind of Chinese medicine preparation for the treatment of gastric cancer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fomes Fomentarius 42 ~ 62 Fen Radix Polemonii Liniflori 37 ~ 57 parts of Herba Ardisiae Maculosaes 36 ~ 53 portions of Bulbus Fritillariae Uninbracteataes 32 ~ 52 parts
Cortex Linderae Fragrantis 32 ~ 52 parts of Fructus Chebulaes 31 ~ 48 parts of Fructus Corni 27 ~ 47 parts of Fructus Psoraleaes 27 ~ 47 parts
Purple bubble 26 ~ 43 parts of Radix Stephaniae Cepharanthaes, 22 ~ 42 parts of Rhizoma Atractylodis 21 ~ 38 parts of Maifanitums 21 ~ 38 parts
11 ~ 28 parts, Fructus rosae multiflorae 22 ~ 42 parts of Fructus Aristolochiae Kwangsiensiss 17 ~ 37 parts of Herba Aristolochiaes 16 ~ 33 parts of Fructus Amomi Rotunduss.
3. a kind of Chinese medicine preparation for the treatment of gastric cancer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fomes Fomentarius 47 ~ 57 Fen Radix Polemonii Liniflori 42 ~ 52 parts of Herba Ardisiae Maculosaes 40 ~ 49 portions of Bulbus Fritillariae Uninbracteataes 37 ~ 47 parts
Cortex Linderae Fragrantis 37 ~ 47 parts of Fructus Chebulaes 35 ~ 44 parts of Fructus Corni 32 ~ 42 parts of Fructus Psoraleaes 32 ~ 42 parts
Purple bubble 30 ~ 39 parts of Radix Stephaniae Cepharanthaes, 27 ~ 37 parts of Rhizoma Atractylodis 25 ~ 34 parts of Maifanitums 25 ~ 34 parts
15 ~ 24 parts, Fructus rosae multiflorae 27 ~ 37 parts of Fructus Aristolochiae Kwangsiensiss 22 ~ 32 parts of Herba Aristolochiaes 20 ~ 29 parts of Fructus Amomi Rotunduss.
4. a kind of Chinese medicine preparation for the treatment of gastric cancer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fomes Fomentarius 52 Fen Radix Polemonii Liniflori 47 parts of Herba Ardisiae Maculosaes 45 portions of Bulbus Fritillariae Uninbracteataes 42 parts
Cortex Linderae Fragrantis 42 parts of Fructus Chebulaes 40 parts of Fructus Corni 37 parts of Fructus Psoraleaes 37 parts
Purple bubble 35 parts of Radix Stephaniae Cepharanthaes, 32 parts of Rhizoma Atractylodis 30 parts of Maifanitums 30 parts
20 parts, Fructus rosae multiflorae 32 parts of Fructus Aristolochiae Kwangsiensiss 27 parts of Herba Aristolochiaes 25 parts of Fructus Amomi Rotunduss.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine preparation of gastric cancer, it is characterized in that: comprise following processing step:
(1) Fomes Fomentarius, Radix Polemonii Liniflori, Cortex Linderae Fragrantis, Zi Pao, Radix Stephaniae Cepharanthae and Fructus rosae multiflorae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, for subsequent use;
(2) Herba Ardisiae Maculosae, Fructus Chebulae, Fructus Corni, Fructus Psoraleae and Fructus Amomi Rotundus are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 70% of 3 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.10 ~ 1.12, for subsequent use;
(3) Herba Aristolochiae and Rhizoma Atractylodis decontamination are cleaned, dry, put into pot, slow fire is fried to surface in coke yellow, and taking-up is dried in the air cool, grinds into powder, crosses 180 order fine powders, for subsequent use;
(4) by Bulbus Fritillariae Uninbracteatae, Maifanitum and Fructus Aristolochiae Kwangsiensis decontamination respectively, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(5) by the filtrate obtained by above-mentioned steps (1) ~ (4), thick paste and fine powder mixing, make tablet, obtain the Chinese medicine preparation for the treatment of gastric cancer of the present invention.
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| CN101301409A (en) * | 2008-06-06 | 2008-11-12 | 陆利勇 | Oral Chinese medicine for treating gastric ulcer with haematemesis |
| CN101757276A (en) * | 2010-02-11 | 2010-06-30 | 傅天锡 | Traditional Chinese herbal medicine for treating arthromeningitis |
| CN101954006A (en) * | 2010-09-06 | 2011-01-26 | 吴达改 | Chinese medicament for treating insomnia |
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| CN101301409A (en) * | 2008-06-06 | 2008-11-12 | 陆利勇 | Oral Chinese medicine for treating gastric ulcer with haematemesis |
| CN101757276A (en) * | 2010-02-11 | 2010-06-30 | 傅天锡 | Traditional Chinese herbal medicine for treating arthromeningitis |
| CN101954006A (en) * | 2010-09-06 | 2011-01-26 | 吴达改 | Chinese medicament for treating insomnia |
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