CN103520623A - Traditional Chinese medicine preparation used for treating gastric ulcer - Google Patents
Traditional Chinese medicine preparation used for treating gastric ulcer Download PDFInfo
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- CN103520623A CN103520623A CN201310553692.8A CN201310553692A CN103520623A CN 103520623 A CN103520623 A CN 103520623A CN 201310553692 A CN201310553692 A CN 201310553692A CN 103520623 A CN103520623 A CN 103520623A
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Abstract
The invention discloses a traditional Chinese medicine preparation used for treating gastric ulcer, and belongs to the field of traditional Chinese medicine. Effective components of the traditional Chinese medicine preparation comprise peach kernel, Chinese yam, mottled ardisia, streptocaulon, dwarf galangal, evodia, lesser galangal, cyperus, codonopsis, lablab, bupleurum, gardenia, nardostachys, millet sprout, jujube and aristolochia stem. The traditional Chinese medicine preparation has the effects of soothing the liver and nourishing blood, moving qi and stimulating appetite, dissipating cold and relieving pains and tonifying qi and harmonizing the center, has remarkable treatment effects on gastric ulcer caused by various reasons, and is safe and reliable, good in stability, low in cost, free of toxic and side effects and worth being widely popularized and used in clinic, and chosen medicinal materials are matched with one another and achieve complementarity.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation for the treatment of gastric ulcer.
Background technology
Gastric ulcer is a kind of chronic digestive system disease, and the final formation of peptic ulcer is due to due to gastric acid/pepsin autodigestion, and gastric acid is the deciding factor that ulcer occurs; Acute stress can cause stress ulcer.The people of long-term psychentonia, anxiety or anxious state of mind easily suffers from peptic ulcer; In some rare genetic syndromes, as multiple endocrine gland adenoma I type, systemic mastocytosis etc., peptic ulcer is its clinical manifestation part; There is motility disturbances of the stomach in part patients w ith peptic ulcer disease, as gastric acid secretion due to gastric emptying increase and Duodenogastric reflux due to bile, pancreatic juice and the damage of LYSOLECITHIN SUNLECITHIN A to gastric mucosa.
The concurrent pyloric obstruction of Peptic Ulcers approximately 10% possibility, betides duodenal ulcer mostly, is secondly pyloric canal or PPU.Concurrent pyloric obstruction old people is common for peptic ulcer, take male as main.Due to the extensive use of various effective anti-ulcer medicaments, this kind of complication obviously reduces in recent years.Pyloric obstruction has organic and functional two kinds.The former is because chronic ulcer causes fibrosis under mucosa, causes cicatricial stricture, and medical treatment is invalid, often needs surgical operation therapy; The latter causes that due to ulcer surrounding tissue inflammation due to congestion and edema and pyloric reflex spasm, medical treatment is effective.
At present, most scholars think that malignant change of benign gastric ulcer exists, and its canceration rate estimation is 1%～7%, and malignant change of benign gastric ulcer often betides ulcer edge, and canceration does not generally occur duodenal ulcer.The medicine of western medicine gastric ulcer is more at present, and these medicines are merely able to eliminate surperficial pain symptom, do not remove the root of disease, and life-time service is all very large to the side effect of human body, and after treatment, easily recurrence, is usually difficult to radical cure.
For this reason, the medicine that we are badly in need of developing a kind of safe without toxic side effect is treated gastric ulcer, reaches the effect for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of gastric ulcer, Chinese medicine preparation of the present invention have soothing the liverly nourish blood, circulation of qi promoting appetizing, dispersing cold for relieving pain, QI invigorating and in effect, the gastric ulcer causing for a variety of causes has significant curative effect, and safe and reliable, good stability, with low cost, without any side effects, selected medical material compatibility brings out the best in each other, and is worth wide popularization and application clinically.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for gastric ulcer, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
59～84 parts of 59～89 parts of Radix Streptocauli Griffithiis of 64～89 parts of Herba Ardisiae Maculosaes of 64～94 portions of Rhizoma Dioscoreaes of Semen Persicae
44～74 parts of 49～79 portions of Rhizoma Cyperis of 49～79 portions of Rhizoma Alpiniae Officinarums of 54～84 portions of Fructus Evodiaes of Rhizoma alpiniae pumilae
34～59 parts of 34～64 portions of Fructus Gardeniaes of 39～69 parts of Radix Bupleuri of 44～74 portions of Semen Lablab Albums of Radix Codonopsis
14～44 parts of 19～49 parts of Herba Aristolochiaes of 24～54 portions of Fructus Jujubaes of 29～59 parts of Fructus Setariae Germinatuss of Radix Et Rhizoma Nardostachyos.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
64～79 parts of 64～84 parts of Radix Streptocauli Griffithiis of 69～84 parts of Herba Ardisiae Maculosaes of 69～89 portions of Rhizoma Dioscoreaes of Semen Persicae
49～69 parts of 54～74 portions of Rhizoma Cyperis of 54～74 portions of Rhizoma Alpiniae Officinarums of 59～79 portions of Fructus Evodiaes of Rhizoma alpiniae pumilae
39～54 parts of 39～59 portions of Fructus Gardeniaes of 44～64 parts of Radix Bupleuri of 49～69 portions of Semen Lablab Albums of Radix Codonopsis
19～39 parts of 24～44 parts of Herba Aristolochiaes of 29～49 portions of Fructus Jujubaes of 34～54 parts of Fructus Setariae Germinatuss of Radix Et Rhizoma Nardostachyos.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
69～74 parts of 69～79 parts of Radix Streptocauli Griffithiis of 74～79 parts of Herba Ardisiae Maculosaes of 74～84 portions of Rhizoma Dioscoreaes of Semen Persicae
54～64 parts of 59～69 portions of Rhizoma Cyperis of 59～69 portions of Rhizoma Alpiniae Officinarums of 64～74 portions of Fructus Evodiaes of Rhizoma alpiniae pumilae
44～49 parts of 44～54 portions of Fructus Gardeniaes of 49～59 parts of Radix Bupleuri of 54～64 portions of Semen Lablab Albums of Radix Codonopsis
24～34 parts of 29～39 parts of Herba Aristolochiaes of 34～44 portions of Fructus Jujubaes of 39～49 parts of Fructus Setariae Germinatuss of Radix Et Rhizoma Nardostachyos.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
72 parts of 74 parts of Radix Streptocauli Griffithiis of 76 parts of Herba Ardisiae Maculosaes of 79 portions of Rhizoma Dioscoreaes of Semen Persicae
59 parts of 64 portions of Rhizoma Cyperis of 64 portions of Rhizoma Alpiniae Officinarums of 69 portions of Fructus Evodiaes of Rhizoma alpiniae pumilae
46 parts of 49 portions of Fructus Gardeniaes of 54 parts of Radix Bupleuri of 59 portions of Semen Lablab Albums of Radix Codonopsis
29 parts of 34 parts of Herba Aristolochiaes of 39 portions of Fructus Jujubaes of 44 parts of Fructus Setariae Germinatuss of Radix Et Rhizoma Nardostachyos.
A preparation method for the Chinese medicine preparation of gastric ulcer, comprises following processing step:
(1) Semen Persicae, Herba Ardisiae Maculosae and Herba Aristolochiae are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate for later use;
(2) Rhizoma Dioscoreae, Rhizoma alpiniae pumilae, Rhizoma Cyperi, Radix Bupleuri, Fructus Gardeniae, Radix Et Rhizoma Nardostachyos and Fructus Jujubae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10～1.16, standby;
(3) by Radix Streptocauli Griffithii and Radix Codonopsis decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 200 order fine powders, standby;
(4) Fructus Evodiae, Rhizoma Alpiniae Officinarum and Semen Lablab Album are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(5) get Fructus Setariae Germinatus decontamination, put into pot, intense fire is fried to surface coke yellow, and taking-up cools, and is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(6) above-mentioned steps (1)～(5) prepared filtrate, thick paste, fine powder and juice are mixed, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of gastric ulcer of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Semen Persicae: bitter in the mouth, sweet, property is flat; GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Cure mainly amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation." herbal classic is met former " carries: " Semen Persicae, the special medicine closing for blood stasis blood.Bitter to let out stagnant blood, sweetly with tissue regeneration promoting blood, control invasion of the blood-chamber by heat, the stasis of blood amass lump in the abdomen, malaria with splenomegaly, cardiac and abdominal pain, the blood agglomeration of the Liver Channel that also falls apart." modern medicine study confirmation, Semen Persicae alcohol extract can increase vein blood vessel flow, and vasodilator increases femoral artery blood flow, reduces vascular resistance, and blood vessel wall is had to direct dilating effect, suppresses in addition in addition blood coagulation and haemolysis.
Rhizoma Dioscoreae: sweet in the mouth, property is flat; Enter spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, and leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst." book on Chinese herbal medicine just " carries: " Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency, grows essence and reinforce the kidney, and controls weakness, treats five kinds of strain and seven kinds of impairment.The light property of its gas is slow, non-may be full-time, therefore spleen reinforcing lung must mainly be joined, art, the kidney invigorating water must monarch Zhu,, puckery foul leukorrhea must be broken therefore with grinding, solid spermatorrhea is held Herba cuscutae and helped mutually.All balls consolidate pill, also should smash end for sticking with paste.Nature and flavor are weak in a word, but can firmly help and make.”
Herba Ardisiae Maculosae: acrid in the mouth, hardship, slightly warm in nature; Return liver, kidney, lung meridian.Promoting blood circulation and stopping pain, clearing throat.Cure mainly traumatic injury, fracture, rheumatic arthralgia, diphtheria, laryngopharynx swelling and pain, gastric ulcer.
Radix Streptocauli Griffithii: bitter in the mouth, micro-sweet, cool in nature; Return spleen, kidney, urinary bladder channel.Heat-clearing and toxic substances removing, scattered silt pain relieving.For cat fever, enteritis, dysentery, stomachache, treating swelling and pain by traumatic injury, venom." Guangxi medicine is planted figure will " carries: " treating acute and chronic enteritis, heart peratodynia, red Hakuri disease, diseases caused by exogenous pathogenic factor eruptive disease, snakebite.”
Rhizoma alpiniae pumilae: acrid in the mouth, micro-hardship, warm in nature; Return spleen, stomach warp.Expelling wind and removing dampness, promoting the circulation of QI to relieve pain.The wet beast pain of main air, diarrhoea, stomachache, traumatic injury.
The Fructus Evodiae: sour-puckery flavor, slightly warm in nature; Enter liver, stomach warp.Invigorating the liver and kidney, arresting seminal emission gas, solid collapse, stomach invigorating tonifying YANG, the traditional Chinese medical science is conventional shakes the diseases such as scattered pulse, neurasthenia, menoxenia with treatment soreness of waist and knee joint, dizzy, tinnitus, seminal emission, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart.Can suppress dysentery bacterium, Bacillus typhi, golden yellow puckery staphylococcus and some dermatophytes, have diuresis, blood pressure lowering, protective effect on cancer risk.
Rhizoma Alpiniae Officinarum: acrid in the mouth, hot in nature; Return spleen, stomach warp.Dispersing cold for relieving pain, warming middle-JIAO to arrest vomiting.For coldness and pain in the epigastrium, gastrofrigid vomiting, belch acid regurgitation." book on Chinese herbal medicine converges and says " carries: " Rhizoma Alpiniae Officinarum, the medicine of dispelling cold and dampness, warming the spleen stomach also.If old man's spleen-kidney vacuity cold, the diarrhea of having loose bowels, married woman's heart stomach sudden pain, because of dysphagia related to QI disorder, because of cold-phlegm person, the hot pure sun of this medicine, except all chronic diseaseses, merit and osmanthus, attached equal." modern medicine study confirms, Rhizoma Alpiniae Officinarum water extract and ether extract can show the water logging of antagonism mice stress type ulcer and rat hydrochloric acid traumatic ulcer, and has obvious warming middle-JIAO to relieve pain effect.
Rhizoma Cyperi: acrid in the mouth, micro-hardship, sweet, property is flat; Enter liver, tri-jiao channel.The resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving, antiabortive.Cure mainly distending pain over the hypochondrium, mammary swelling is educated, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement." detailed outline " carries: " the cold epidemic disease of the seasonal epidemic pathogens that falls apart, sharp three warmers, solution six kinds of stagnation-syndromes, the diet that disappears gathers, phlegm retention feeling of fullness, edema of dorsum of the foot; abdominal distention, beriberi, stops trusted subordinate, limbs, head, order, tooth, all pains of ear, and ulcer sores is spitted blood; hematochezia, hematuria, married woman's bleeding not during menses, the moon waits uncomfortable, tire all kinds of diseases and ailments in front puerperal.”
Radix Codonopsis: sweet in the mouth, micro-acid, property is flat; Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst." Chinese crude drug handbook " carries: " control asthenia internal injury, intestinal cold in the stomach, the sliding chronic dysentery of rushing down, asthma excessive thirst, heating spontaneous perspiration, metrorrhagia, tire produce all diseases.”
Semen Lablab Album: sweet in the mouth, property is micro-wet; Enter spleen, stomach two warps.Tonifying the spleen and stomach, and middle removing dampness, relieve summer heating Detoxication.Cure mainly weakness of the spleen and stomach, have loose bowels, vomiting, accumulates in heat-damp in summer, abdominal distention, and the inferior disease of red and white leukorrhea, again can alcoholic intoxication." Chinese Pharmacopoeia " carries: " strengthening the spleen and stomach, clearing away summer-heat is wet.For weakness of the spleen and stomach, diarrhea due to summer heat and dampness, leucorrhea.”
Radix Bupleuri: bitter in the mouth, pungent, cold nature; Return liver, gallbladder meridian.Expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Cure cold heating, cold and heat deficient fever, children's's varioliform exanthema waste heat, emaciation and sallow complexion abdominal part expands, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus comes off, menoxenia.
Fructus Gardeniae: bitter in the mouth is cold in nature, nontoxic; GUIXIN, liver, lung, stomach, tri-jiao channel.Pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, cooling blood for hemostasis.Cure mainly calentura vexed, liver-fire conjunctival congestion, headache, jaundice due to damp-heat, stranguria, dysentery hematuria, aphtha of the mouth and tongue, sore swollen toxin, sprains and swells and ache.Materia Medica of Decoction carries: " Fructus Gardeniae diuresis, real non-diuresis, lung heat clearing also, normal lung-QI and changing, the mansion that bladder is body fluid, urine obtains this gasification and goes out also.The Decoction of Capejasmine and Fermented Soybean is controlled agitation, tired person's gas also, hot-tempered person's blood also, the main lung of gas, the main kidney of blood, therefore with Fructus Gardeniae, to control lung, be tired of, hot-tempered to control kidney with fragrant fermented soya beans, salted or other wise.”
Radix Et Rhizoma Nardostachyos: acrid in the mouth, sweet, warm in nature; Return spleen, stomach warp.Regulating QI to relieve pain, activating spleen and strengthening stomach.Cure mainly coldness and pain in the epigastrium distension, anorexia, chest pain, toothache, tumbling down is grieved, beriberi edema, cramp caused by acute vomiting and diarrhea." modern Practical Chinese medicinal " carries: " be applicable to headache, stomachache and the card such as depressed, and can drive ascarid, all because of the ascarid person that sends out infantile convulsion, effective with this.”
Fructus Setariae Germinatus: sweet in the mouth, property is flat; Return spleen, stomach warp.Help digestion and in, spleen benefiting and stimulating the appetite.For food stagnation, do not disappear, abdominal distention halitosis, weakness of the spleen and stomach, not hungry lack of appetite, stagnates and does not disappear." Bencao Jingshu " carries: " tiller rice be rice tiller also.The property of tool biochemistry, thus be digestion-promoting spleen-invigorating, appetizing and in key medicine, taste and in from pestilence, gas under, heat is from except also.”
Fructus Jujubae: sweet in the mouth, warm in nature; Return spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, the mitigation property of medicine.For weakness of the spleen and stomach, fatigue and weakness, the micro-yellow person of blood deficiency, feel at ease to keep god, appetite stimulator.Modern pharmacology discovery, Fructus Jujubae contains the multiple nutritional components such as protein, fat, carbohydrate, organic acid, vitamin A, vitamin C, micro-calcium, has warming spleen and stomach for dispelling cold, regulating QI to relieve pain, the effect of the appetizing of being amusing.
Herba Aristolochiae: bitter in the mouth, warm in nature; Return liver,spleen,kidney warp.Circulation of qi promoting removing dampness, promoting blood circulation and stopping pain.Cure mainly stomachache, colicky, edema during pregnancy, puerperal, vim and vigour were suffered from abdominal pain, rheumatalgia." book on Chinese herbal medicine is new again " carries: " removing heat from blood and promoting blood circulation, removes wind dampness removing, walks meridians, the double swollen pain of waist lower limb of controlling.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention have soothing the liverly nourish blood, circulation of qi promoting appetizing, dispersing cold for relieving pain, QI invigorating and in effect, the gastric ulcer causing for a variety of causes has significant curative effect, and safe and reliable, good stability, with low cost, without any side effects, selected medical material compatibility brings out the best in each other, and is worth wide popularization and application clinically.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Semen Persicae 89g Rhizoma Dioscoreae 84g Herba Ardisiae Maculosae 84g Radix Streptocauli Griffithii 79g
Rhizoma alpiniae pumilae 79g Fructus Evodiae 74g Rhizoma Alpiniae Officinarum 74g Rhizoma Cyperi 69g
Radix Codonopsis 69g Semen Lablab Album 64g Radix Bupleuri 59g Fructus Gardeniae 54g
Radix Et Rhizoma Nardostachyos 54g Fructus Setariae Germinatus 49g Fructus Jujubae 44g Herba Aristolochiae 39g.
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) Semen Persicae, Herba Ardisiae Maculosae and Herba Aristolochiae are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate for later use;
(2) Rhizoma Dioscoreae, Rhizoma alpiniae pumilae, Rhizoma Cyperi, Radix Bupleuri, Fructus Gardeniae, Radix Et Rhizoma Nardostachyos and Fructus Jujubae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10～1.16, standby;
(3) by Radix Streptocauli Griffithii and Radix Codonopsis decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 200 order fine powders, standby;
(4) Fructus Evodiae, Rhizoma Alpiniae Officinarum and Semen Lablab Album are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(5) get Fructus Setariae Germinatus decontamination, put into pot, intense fire is fried to surface coke yellow, and taking-up cools, and is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(6) above-mentioned steps (1)～(5) prepared filtrate, thick paste, fine powder and juice are mixed, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of gastric ulcer of the present invention.Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), after meal warm water delivery services; Within 6 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, severe one can be fully recovered 3～4 courses for the treatment of.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Semen Persicae 84g Rhizoma Dioscoreae 79g Herba Ardisiae Maculosae 79g Radix Streptocauli Griffithii 74g
Rhizoma alpiniae pumilae 74g Fructus Evodiae 69g Rhizoma Alpiniae Officinarum 69g Rhizoma Cyperi 64g
Radix Codonopsis 64g Semen Lablab Album 59g Radix Bupleuri 54g Fructus Gardeniae 49g
Radix Et Rhizoma Nardostachyos 49g Fructus Setariae Germinatus 44g Fructus Jujubae 39g Herba Aristolochiae 34g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Semen Persicae 79g Rhizoma Dioscoreae 76g Herba Ardisiae Maculosae 74g Radix Streptocauli Griffithii 72g
Rhizoma alpiniae pumilae 69g Fructus Evodiae 64g Rhizoma Alpiniae Officinarum 64g Rhizoma Cyperi 59g
Radix Codonopsis 59g Semen Lablab Album 54g Radix Bupleuri 49g Fructus Gardeniae 46g
Radix Et Rhizoma Nardostachyos 44g Fructus Setariae Germinatus 39g Fructus Jujubae 34g Herba Aristolochiae 29g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Semen Persicae 74g Rhizoma Dioscoreae 74g Herba Ardisiae Maculosae 69g Radix Streptocauli Griffithii 69g
Rhizoma alpiniae pumilae 64g Fructus Evodiae 59g Rhizoma Alpiniae Officinarum 59g Rhizoma Cyperi 54g
Radix Codonopsis 54g Semen Lablab Album 49g Radix Bupleuri 44g Fructus Gardeniae 44g
Radix Et Rhizoma Nardostachyos 39g Fructus Setariae Germinatus 34g Fructus Jujubae 29g Herba Aristolochiae 24g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Semen Persicae 69g Rhizoma Dioscoreae 69g Herba Ardisiae Maculosae 64g Radix Streptocauli Griffithii 64g
Rhizoma alpiniae pumilae 59g Fructus Evodiae 54g Rhizoma Alpiniae Officinarum 54g Rhizoma Cyperi 49g
Radix Codonopsis 49g Semen Lablab Album 44g Radix Bupleuri 39g Fructus Gardeniae 39g
Radix Et Rhizoma Nardostachyos 34g Fructus Setariae Germinatus 29g Fructus Jujubae 24g Herba Aristolochiae 19g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
Chinese medicine preparation as treatment gastric ulcer, the routine clinical observation of patients w ith peptic ulcer disease 200 that selection is made a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups, treatment group 100 examples, wherein male's 51 examples at random, women's 49 examples, 31～75 years old age, 51.4 years old mean age, the shortest person of the course of disease 2 months, elder 6 years, average 3.5 years.Matched group 100 examples, male's 52 examples wherein, women's 48 examples, 30～74 years old age, 50.7 years old mean age, the shortest person of the course of disease 3 months, elder 7 years, average 3.2 years.The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), after meal warm water delivery services; Within 6 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, severe one can be fully recovered 3～4 courses for the treatment of.
Matched group is taken Cimitidine Tablets, oral, every day 3 times, each 1 (every 0.4g), after meal warm water delivery service; Within 8 days, be 1 course for the treatment of, 3 courses for the treatment of of the lighter, severe one can be fully recovered 4～5 courses for the treatment of, and the person of being in a bad way is conventionally invalid.
3, efficacy determination:
(1) cure: gastral cavilty twinge, abdominal distention, belch, the symptom such as feel sick all disappear, and it is normal that physical function recovers.
(3) take a turn for the better: above-mentioned symptom alleviates to some extent, and physical function makes moderate progress.
(4) invalid: by treating rear symptom without being clearly better.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 71 examples, 25 examples that take a turn for the better, invalid 4 examples, cure rate 71%, total effective rate 96%.
In matched group, cure 41 examples, 32 examples that take a turn for the better, invalid 27 examples, cure rate 41%, total effective rate 73%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
5, model case is for example:
(1) side certain, female, 35 years old, business personnel, Yuncheng, Shanxi people, patient because of the fatigue of working, pressure larger, and diet likes vinegar-pepper raw food, causes suffering from gastric ulcer 1 year, often feel gastral cavilty twinge, abdominal distention, belch, feel sick, and health become thin.To our hospital afterwards, take Chinese medicine preparation of the present invention after 3 courses for the treatment of, stomachache is not reaccessed, abdominal distention, belch, the transference cure of feeling sick, body weight increases than before, through gastroscopy gastric ulcer, fully recovers.
(2) Tan, man, 41 years old, teacher, people from Yangzhou, Jiangsu, patient suffers from gastric ulcer for many years, often feels hungry uncomfortable, pantothenic acid, and, sometimes there is melena in Upper abdominal pain after the meal, took multi-medicament and all fail to effect a radical cure, Chang Fanfu outbreak.To our hospital afterwards, take Chinese medicine preparation of the present invention after 3 courses for the treatment of, the transference cures such as pantothenic acid and after the meal Upper abdominal pain, check gastric ulcer disappears, patient's recovery from illness, so far not recurrence.
(3) Zou, man, 58 years old, businessman, From Shandong Rizhao people, ill 3 years of patient, can not eat the irritant thing of stomach, usually often occurs stomachache, acid regurgitation, vomiting phenomenon, to our hospital, take Chinese medicine preparation of the present invention after 2 courses for the treatment of, transference cure, follows up a case by regular visits to after 1 year without recurrence.
(4) land, female, 70 years old, retired worker, people from Shenyang, Liaoning.Patient is for many years ill, starts to occur rhythmicity stomachache after the half an hour of having a dinner, to our hospital, takes Chinese medicine preparation of the present invention after 1 course for the treatment of, and stomachache alleviates, and number of times reduces, and continues to take Chinese medicine preparation of the present invention after 2 courses for the treatment of, and stomachache disappears, and follows up a case by regular visits to, so far not recurrence.
Claims (5)
1. a Chinese medicine preparation for the treatment of gastric ulcer, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
59～84 parts of 59～89 parts of Radix Streptocauli Griffithiis of 64～89 parts of Herba Ardisiae Maculosaes of 64～94 portions of Rhizoma Dioscoreaes of Semen Persicae
44～74 parts of 49～79 portions of Rhizoma Cyperis of 49～79 portions of Rhizoma Alpiniae Officinarums of 54～84 portions of Fructus Evodiaes of Rhizoma alpiniae pumilae
34～59 parts of 34～64 portions of Fructus Gardeniaes of 39～69 parts of Radix Bupleuri of 44～74 portions of Semen Lablab Albums of Radix Codonopsis
14～44 parts of 19～49 parts of Herba Aristolochiaes of 24～54 portions of Fructus Jujubaes of 29～59 parts of Fructus Setariae Germinatuss of Radix Et Rhizoma Nardostachyos.
2. a kind of Chinese medicine preparation for the treatment of gastric ulcer according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
64～79 parts of 64～84 parts of Radix Streptocauli Griffithiis of 69～84 parts of Herba Ardisiae Maculosaes of 69～89 portions of Rhizoma Dioscoreaes of Semen Persicae
49～69 parts of 54～74 portions of Rhizoma Cyperis of 54～74 portions of Rhizoma Alpiniae Officinarums of 59～79 portions of Fructus Evodiaes of Rhizoma alpiniae pumilae
39～54 parts of 39～59 portions of Fructus Gardeniaes of 44～64 parts of Radix Bupleuri of 49～69 portions of Semen Lablab Albums of Radix Codonopsis
19～39 parts of 24～44 parts of Herba Aristolochiaes of 29～49 portions of Fructus Jujubaes of 34～54 parts of Fructus Setariae Germinatuss of Radix Et Rhizoma Nardostachyos.
3. a kind of Chinese medicine preparation for the treatment of gastric ulcer according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
69～74 parts of 69～79 parts of Radix Streptocauli Griffithiis of 74～79 parts of Herba Ardisiae Maculosaes of 74～84 portions of Rhizoma Dioscoreaes of Semen Persicae
54～64 parts of 59～69 portions of Rhizoma Cyperis of 59～69 portions of Rhizoma Alpiniae Officinarums of 64～74 portions of Fructus Evodiaes of Rhizoma alpiniae pumilae
44～49 parts of 44～54 portions of Fructus Gardeniaes of 49～59 parts of Radix Bupleuri of 54～64 portions of Semen Lablab Albums of Radix Codonopsis
24～34 parts of 29～39 parts of Herba Aristolochiaes of 34～44 portions of Fructus Jujubaes of 39～49 parts of Fructus Setariae Germinatuss of Radix Et Rhizoma Nardostachyos.
4. a kind of Chinese medicine preparation for the treatment of gastric ulcer according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
72 parts of 74 parts of Radix Streptocauli Griffithiis of 76 parts of Herba Ardisiae Maculosaes of 79 portions of Rhizoma Dioscoreaes of Semen Persicae
59 parts of 64 portions of Rhizoma Cyperis of 64 portions of Rhizoma Alpiniae Officinarums of 69 portions of Fructus Evodiaes of Rhizoma alpiniae pumilae
46 parts of 49 portions of Fructus Gardeniaes of 54 parts of Radix Bupleuri of 59 portions of Semen Lablab Albums of Radix Codonopsis
29 parts of 34 parts of Herba Aristolochiaes of 39 portions of Fructus Jujubaes of 44 parts of Fructus Setariae Germinatuss of Radix Et Rhizoma Nardostachyos.
5. as described in claim 1～4 any one, treat a preparation method for the Chinese medicine preparation of gastric ulcer, it is characterized in that: comprise following processing step:
(1) Semen Persicae, Herba Ardisiae Maculosae and Herba Aristolochiae are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate for later use;
(2) Rhizoma Dioscoreae, Rhizoma alpiniae pumilae, Rhizoma Cyperi, Radix Bupleuri, Fructus Gardeniae, Radix Et Rhizoma Nardostachyos and Fructus Jujubae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10～1.16, standby;
(3) by Radix Streptocauli Griffithii and Radix Codonopsis decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 200 order fine powders, standby;
(4) Fructus Evodiae, Rhizoma Alpiniae Officinarum and Semen Lablab Album are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(5) get Fructus Setariae Germinatus decontamination, put into pot, intense fire is fried to surface coke yellow, and taking-up cools, and is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(6) above-mentioned steps (1)～(5) prepared filtrate, thick paste, fine powder and juice are mixed, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of gastric ulcer of the present invention.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105343800A (en) * | 2015-12-14 | 2016-02-24 | 陈如燕 | Traditional Chinese medicine preparation for curing gastric ulcer and preparation method thereof |
| CN110113958A (en) * | 2016-12-16 | 2019-08-09 | 韩国韩医学硏究院 | Contain Semen Lablab Album extract as effective component for eliminating the composition for being still drank after a night and preventing, improve or treat Alcoholic gastrointestinal disease |
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| CN102309696A (en) * | 2011-09-22 | 2012-01-11 | 黄雨昕 | Traditional Chinese medicine for treating gastric ulcer |
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| CN102309696A (en) * | 2011-09-22 | 2012-01-11 | 黄雨昕 | Traditional Chinese medicine for treating gastric ulcer |
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| 牛玉生: "中西医结合治疗消化性溃疡120例", 《山东中医杂志》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105343800A (en) * | 2015-12-14 | 2016-02-24 | 陈如燕 | Traditional Chinese medicine preparation for curing gastric ulcer and preparation method thereof |
| CN110113958A (en) * | 2016-12-16 | 2019-08-09 | 韩国韩医学硏究院 | Contain Semen Lablab Album extract as effective component for eliminating the composition for being still drank after a night and preventing, improve or treat Alcoholic gastrointestinal disease |
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