CN104435520A - Traditional Chinese medicine formula for treating pancreatic cancer and preparation method of traditional Chinese medicine formula for treating pancreatic cancer - Google Patents
Traditional Chinese medicine formula for treating pancreatic cancer and preparation method of traditional Chinese medicine formula for treating pancreatic cancer Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine formula for treating the pancreatic cancer and a preparation method of the traditional Chinese medicine formula for treating the pancreatic cancer. The traditional Chinese medicine formula comprises, by weight, 5-10 parts of oldenlandia diffusa, 3-8 parts of paris polyphylla, 5-8 parts of salvia chinensis, 5-8 parts of selaginella doederleinii, 5-8 parts of sago cycas leaves, 3-8 parts of hedyotis tenelliflora, 3-8 parts of cleavers, 3-5 parts of radix bupleuri, 3-5 parts of polygonum cuspidatum, 3-5 parts of manufactured rhizoma cyperi, 3-5 parts of skullcap, 3-5 parts of yellow grass flowers, 3-5 parts of witloof, 3-5 parts of blue flower gentian, 3-5 parts of swertia punicea, 3-8 parts of angelica sinensis, 3-8 parts of poria cocos and 3-8 parts of gynostemma pentaphyllum. The preparation method includes the step that a preparation is decocted by water. By means of the traditional Chinese medicine formula, the effects of soothing liver-gallbladder, promoting blood circulation to remove blood stasis, clearing heat, promoting diuresis, breaking accumulation and removing stasis of the traditional Chinese medicines are used, so that cancer breeding is restrained, cancer diffusion and transferring is controlled, the immunity is strengthened, pains can be stopped, tumors can be eliminated, the pains of a patient can be reduced, and the life of the patient can be rescued.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine formula for the treatment of cancer of pancreas and preparation method thereof.
Background technology
Cancer of pancreas is that a kind of grade malignancy is very high, the malignant tumor of digestive tract that Diagnosis and Treat is all very difficult, and about 90% for originating from the duct adenocarcinoma of glandular tube epithelium.Its M & M obviously rises in recent years.5 years survival rate <1% are one of the poorest malignant tumor of prognosis.The early stage diagnosis rate of cancer of pancreas is not high, and operative mortality is higher, and cure rate is very low.Primary disease sickness rate male is higher than women, and the ratio of men and women is 1.5 ~ 2:1, and male patient is common far beyond premenopausal women, and sickness rate and the male of postmenopausal women are similar.
Therapeutic Principle basic at present remains based on surgical operation therapy, in conjunction with Comprehensive Treatments such as chemicotherapies.But the equal defectiveness of method of operation and chemotherapeutic treatment, because of the early diagnosis difficulty of cancer of pancreas, Resection Rate is low, and postoperative five year survival rate is also low; Chemotherapy effectively can hinder cancerous cell, but can kill and wound normal cell and cause the immunologic function of patient suppressed again simultaneously, occurs more complication, brings very big damage to patient body.Chinese patent (CN103007202A) discloses a kind of Chinese medicine composition for the treatment of cancer of pancreas, have the effect of heat-clearing and toxic substances removing, but effective percentage is on the low side, takes mouthfeel difference, and actual popularization has certain restriction.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine formula for the treatment of cancer of pancreas and preparation method thereof, by depressed liver-energy dispersing and function of gallbladder promoting, blood circulation promoting and blood stasis dispelling, the clearing away heat-damp and promoting diuresis of Chinese medicine, the effect of removing mass eliminating stagnation, Tumor suppression is bred, control tumor diffusion transfer, enhancing immunity, and can pain relieving dispersing tumor, alleviate patient's misery, save patients ' lives.
The invention provides a kind of Chinese medicine formula for the treatment of cancer of pancreas, formulated by the raw material of Chinese medicine of following parts by weight: Herba Hedyotidis Diffusae 5 ~ 10 parts, Rhizoma Paridis 3 ~ 8 parts, Herba Salviae Chinensis 5 ~ 8 parts, Herba Selaginellae Doederleinii 5 ~ 8 parts, Folium Cycadis siamensis 5 ~ 8 parts, hedyotis tenelliflora Blume 3 ~ 8 parts, Herba Galii Teneri 3 ~ 8 parts, Radix Bupleuri 3 ~ 5 parts, Rhizoma Polygoni Cuspidati 3 ~ 5 parts, Rhizoma Cyperi (processed) 3 ~ 5 parts, Radix Scutellariae 3 ~ 5 parts, Dendrobium denneanum Kerr. spend 3 ~ 5 parts, Herba Cichorii 3 ~ 5 parts, Herba gentianae veitchiori 3 ~ 5 parts, 3 ~ 5 parts, Herba Swertiae Puniceae, Radix Angelicae Sinensis 3 ~ 8 parts, 3 ~ 8 parts, Poria, Herba Gynostemmatis 3 ~ 8 parts.
More preferably formulated by the raw material of Chinese medicine of following parts by weight: Herba Hedyotidis Diffusae 8 parts, Rhizoma Paridis 6 parts, Herba Salviae Chinensis 6 parts, Herba Selaginellae Doederleinii 6 parts, Folium Cycadis siamensis 7 parts, hedyotis tenelliflora Blume 5 parts, Herba Galii Teneri 5 parts, Radix Bupleuri 4 parts, Rhizoma Polygoni Cuspidati 4 parts, Rhizoma Cyperi (processed) 4 parts, Radix Scutellariae 4 parts, Dendrobium denneanum Kerr. spend 4 parts, Herba Cichorii 4 parts, Herba gentianae veitchiori 4 parts, 4 parts, Herba Swertiae Puniceae, Radix Angelicae Sinensis 5 parts, 5 parts, Poria, Herba Gynostemmatis 5 parts.
Preparation method is made up of following steps: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, does not have medical material 2 ~ 5cm, soaks 1 ~ 2 hour; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 20 ~ 40min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
Pharmacology analysis:
Herba Hedyotidis Diffusae: bitter in the mouth, light, cold in nature; Primary efficacy is heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness; Cure mainly dyspnea and cough due to lung-heat, laryngopharynx swelling and pain, acute appendicitis, furuncle and phyma skin infection, venom, the puckery pain of pyretic stranguria, edema, dysentery, enteritis, jaundice due to damp-heat, be good at the multiple cancerous protuberance for the treatment of.
Rhizoma Paridis: hardship is slightly cold mild toxicity, enters Liver Channel.Function heat-clearing and toxic substances removing, reducing swelling and alleviating pain, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. and determine convulsion; Cure mainly digestive tract carcinoma, pulmonary carcinoma, the cerebral tumor and malignant lymphoma, the clinical stagnant malignant lymphoma of pyretic toxicity harmony, pulmonary carcinoma, nasopharyngeal carcinoma, the cerebral tumor and the digestive system tumor of being used for is as gastric cancer, the esophageal carcinoma, hepatocarcinoma etc.
Herba Salviae Chinensis: function blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, mass dissipating and swelling eliminating; Main icterohepatitis, cancer, menoxenia, dysmenorrhea, amenorrhea, metrorrhagia, has blood in stool, toxic-heat and blood stasis, drenches pain, leukorrhagia, rheumatic ostalgia, scrofula, and skin ulcer swells, acute mastitis, herpes zoster, leprosy, and traumatic injury wound is swollen.
Herba Selaginellae Doederleinii: sweet in the mouth, micro-hardship, puckery, cool in nature.There is heat-clearing and toxic substances removing, expelling wind and removing dampness, hemostasis, the effect such as anticancer.
Folium Cycadis siamensis: return liver, stomach warp.Effect regulating QI to relieve pain, dissipating blood stasis stops blooding, subduing swelling and detoxicating; For various hemorrhage, gastritis, gastric ulcer, hypertension, neuralgia, amenorrhea, cancer.
Hedyotis tenelliflora Blume: bitter, pungent, cool.Function heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For cancer, appendicitis, dysentery; Traumatic injury is controlled in external, venom.
Herba Galii Teneri: pungent, bitter, cool.Function heat-clearing and toxic substances removing, inducing diuresis to remove edema; Cure mainly flu, gingival hemorrhage, acute and chronic appendicitis, urinary system infection, edema, dysmenorrhea, metrorrhagia, leucorrhea, cancer, leukemia; External controls mastitis from the beginning of, carbuncle furuncle and phyma poison, traumatic injury.
Radix Bupleuri: nature and flavor are bitter, are slightly cold.Return liver, gallbladder meridian.There is reconciling superficies and interior, soothing the liver, effect of yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.
Rhizoma Polygoni Cuspidati: micro-hardship, is slightly cold; Return liver, gallbladder, lung meridian; Function is dispeled the wind, dampness removing, and removing blood stasis with potent drugs stimulates the menstrual flow; Cure mainly rheumatism bones and muscles pain, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, women's amenorrhea, lochiostasis, lump in the abdomen, anal fistula hematochezia; Injury from falling down, scalds, malignant boil tinea disease.Arrhythmia and anti-cardiac muscle are lost blood; Blood circulation promoting and blood stasis dispelling.
Rhizoma Cyperi (processed): pungent micro-hardship is sweet is flat; Enter liver, tri-jiao channel.Function cures mainly resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving, antiabortive; Cure mainly distending pain over the hypochondrium, mammary swelling is educated, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation, bleeding not during menses, frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Radix Scutellariae: bitter in the mouth, cold in nature, enters the heart, lung, gallbladder, large intestine channel; There are heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive; Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.Modern pharmacology proves, Radix Scutellariae has the effects such as antibacterial action, antifungic action, antivirus action and antiinflammatory antiallergic action, and does not develop immunity to drugs.
Dendrobium denneanum Kerr. flower: bitter, cool; Enter lung, stomach two warp.Effect heat-clearing and toxic substances removing, cooling blood for hemostasis, liver heat removing function of gallbladder promoting, pain relieving; Cure mainly boil of the nose caused by lung-heat, stomach-fire, laryngopharynx swelling and pain, gums redness, aphtha of the mouth and tongue, bleeding due to blood-heat go out blood disorder, as the disease such as epistaxis, gingival hemorrhage.
Herba Cichorii: mildly bitter flavor, salty, cool in nature; Return spleen, liver, wing, Guang warp.Effect liver heat removing function of gallbladder promoting, invigorating the stomach and promoting digestion, inducing diuresis to remove edema; Cure mainly jaundice due to damp-heat, stomachache lack of appetite, edema oliguria.
Herba gentianae veitchiori: cold in nature, bitter in the mouth.Function liver heat removing gallbladder-heat, removing toxic substances; Be used for the treatment of conjunctival congestion, headache, pharyngitis.Jaundice due to damp-heat, leucorrhea, scrotum swells and ache, and to controlling jaundice due to damp-heat hepatitis, can reduce paddy, pyruvic transaminase, and effect is very good.Treating the liver gallbladder excess-fire superinverse simultaneously, gallbladder, costalgia bitter taste, deaf, ear swells and liver damp invasion of lower energizer, and stranguria with turbid discharge, primary sore is festered, capsulitis inguinal bubo, and the diseases such as pudendal pruritus pain over the perineum are evident in efficacy.
Herba Swertiae Puniceae: bitter, cold.Function.Liver heat removing function of gallbladder promoting, except damp and clearing heat; Control acute icterohepatitis, cholecystitis.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm; There is oxygen lack resistant function; Conditioner body immunity function, there is antitumaous effect; Cosmetology effect; To enrich blood the effect of invigorating blood circulation; Antibacterial, arteriosclerosis effect.
Poria: there is antioxidation, anti-aging, increase immunity, improve the effect of brain cell activity.Poria has stronger diuresis, can treat nephritis, heart failure edema.Also have sedation in addition, effective to neurasthenia.Lightly seasoned property is put down, kind benefiting QI and nourishing blood, and mind tranquilizing and the heart calming, relieves internal heat anticancer; Mild in medicine property and, dampness removing and do not hinder healthy energy, contained pachymic acid has the effect of enhancing immunity, antitumor and calmness, blood sugar lowering etc.; Can be relaxed gastrointestinal smooth muscle, the effects such as gastric acid secretion inhibiting, prevents hepatic necrosis, antibacterial.
Herba Gynostemmatis: bitter in the mouth, micro-sweet, cool in nature.Effect replenishing QI to invigorate the spleen, preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing; There is blood fat reducing, blood sugar lowering, antitumor, defying age, the liver protecting and strengthen the effects such as body immune function.Be mainly used in the propagation of the cancerous cell such as Hepatoma therapy, pulmonary carcinoma, uterus carcinoma, skin carcinoma, have obvious inhibitory action.
Chinese medicine of the present invention, by depressed liver-energy dispersing and function of gallbladder promoting, blood circulation promoting and blood stasis dispelling, the clearing away heat-damp and promoting diuresis of Chinese medicine, the effect of removing mass eliminating stagnation, Tumor suppression is bred, and controls tumor diffusion transfer, enhancing immunity, and can pain relieving dispersing tumor, alleviates patient's misery, saves patients ' lives.
Outcome measure:
1.1 physical data
The present invention carries out clinical observation treatment to 102 routine Pancreas cancer patients, wherein age reckling 18 years old, the maximum 75 years old, 52 years old mean age; Man 66 example, female 36 example.
1.2 Therapeutic Method
Therapeutic Method: patient takes medicine of the present invention, potion on the one, 3 times on the one, serve on 1 month.
1.3 efficacy assessment standard
Effective: tumor size reduces >=50% at least 4 week;
Effective: without significant change at least 4 week, comprise pathological changes and stablize, tumor reduces greatly less than 50%;
Invalid: new focus occurs or original pathological changes expands.
1.4 therapeutic effect:
Effective 51 examples, account for 50.0%, and effective 50 examples, account for 49.0%, and invalid 1 example, accounts for 1.0%, total effective rate 99.0%.
1.5 model cases:
Case 1: model, man, 59 years old, there is abdominal part distending pain without obvious cause in patient before 2 months, can tolerate, and without diagnosis and treatment, rear symptom increases the weight of gradually, medical local hospital.Liver and gall pancreas nuclear magnetic scanning shows: pancreas ditch teat soft mass, the obstructive expansion of pancreatic duct.Patient is further diagnosis and treatment, in general anesthesia descending " exploratory laparotomy, enterodialysis ", find in art that swell thing and surrounding tissue of Diseases In Pancreatic Head 4cm × 3cm × 3cm is fixed, and invade inferior mesenteric vein, cannot excision, then give Chinese medicine of the present invention and treat, after January effectively, tumor size reduces 60%, follows up a case by regular visits to half a year without recurrence.
Case 2: king so-and-so, man, 68 years old, there is polydipsia without obvious cause, become thin in patient, weak before 5 months, and local hospital is diagnosed as type 2 diabetes mellitus, blood glucose improvement after symptomatic treatment.Before 1 month there is stomachache in patient, and with whole body xanthochromia, abdominal CT is shown: extrahepatic duct is expanded, and Gallbladder enlargement, lower common bile duct attenuates, and is diagnosed as obstructive jaundice, head of pancreas space occupying lesion.Abdominal part nuclear magnetic scanning shows: carcinoma of head of pancreas.Give Chinese medicine of the present invention to treat, after January effectively, tumor size reduces 40%, follows up a case by regular visits to half a year without recurrence.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine formula for cancer of pancreas, formulated by the raw material of Chinese medicine of following parts by weight: Herba Hedyotidis Diffusae 8 parts, Rhizoma Paridis 6 parts, Herba Salviae Chinensis 6 parts, Herba Selaginellae Doederleinii 6 parts, Folium Cycadis siamensis 7 parts, hedyotis tenelliflora Blume 5 parts, Herba Galii Teneri 5 parts, Radix Bupleuri 4 parts, Rhizoma Polygoni Cuspidati 4 parts, Rhizoma Cyperi (processed) 4 parts, Radix Scutellariae 4 parts, Dendrobium denneanum Kerr. spend 4 parts, Herba Cichorii 4 parts, Herba gentianae veitchiori 4 parts, 4 parts, Herba Swertiae Puniceae, Radix Angelicae Sinensis 5 parts, 5 parts, Poria, Herba Gynostemmatis 5 parts.
Preparation method is that preparation method is made up of following steps: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, does not have medical material 3cm, soaks 1.5 hours; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 30min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
Embodiment 2:
Treat a Chinese medicine formula for cancer of pancreas, formulated by the raw material of Chinese medicine of following parts by weight: Herba Hedyotidis Diffusae 5 parts, Rhizoma Paridis 8 parts, Herba Salviae Chinensis 5 parts, Herba Selaginellae Doederleinii 8 parts, Folium Cycadis siamensis 5 parts, hedyotis tenelliflora Blume 8 parts, Herba Galii Teneri 3 parts, Radix Bupleuri 5 parts, Rhizoma Polygoni Cuspidati 3 parts, Rhizoma Cyperi (processed) 5 parts, Radix Scutellariae 3 parts, Dendrobium denneanum Kerr. spend 5 parts, Herba Cichorii 3 parts, Herba gentianae veitchiori 5 parts, 3 parts, Herba Swertiae Puniceae, Radix Angelicae Sinensis 8 parts, 3 parts, Poria, Herba Gynostemmatis 8 parts.
Preparation method is that preparation method is made up of following steps: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, does not have medical material 5cm, soaks 1 hour; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 40min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
Embodiment 3:
Treat a Chinese medicine formula for cancer of pancreas, formulated by the raw material of Chinese medicine of following parts by weight: Herba Hedyotidis Diffusae 10 parts, Rhizoma Paridis 3 parts, Herba Salviae Chinensis 8 parts, Herba Selaginellae Doederleinii 5 parts, Folium Cycadis siamensis 8 parts, hedyotis tenelliflora Blume 3 parts, Herba Galii Teneri 8 parts, Radix Bupleuri 3 parts, Rhizoma Polygoni Cuspidati 5 parts, Rhizoma Cyperi (processed) 3 parts, Radix Scutellariae 5 parts, Dendrobium denneanum Kerr. spend 3 parts, Herba Cichorii 5 parts, Herba gentianae veitchiori 3 parts, 5 parts, Herba Swertiae Puniceae, Radix Angelicae Sinensis 3 parts, 8 parts, Poria, Herba Gynostemmatis 3 parts.
Preparation method is that preparation method is made up of following steps: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, does not have medical material 2cm, soaks 2 hours; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 20min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.
Claims (3)
1. treat a Chinese medicine formula for cancer of pancreas, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Herba Hedyotidis Diffusae 5 ~ 10 parts, Rhizoma Paridis 3 ~ 8 parts, Herba Salviae Chinensis 5 ~ 8 parts, Herba Selaginellae Doederleinii 5 ~ 8 parts, Folium Cycadis siamensis 5 ~ 8 parts, hedyotis tenelliflora Blume 3 ~ 8 parts, Herba Galii Teneri 3 ~ 8 parts, Radix Bupleuri 3 ~ 5 parts, Rhizoma Polygoni Cuspidati 3 ~ 5 parts, Rhizoma Cyperi (processed) 3 ~ 5 parts, Radix Scutellariae 3 ~ 5 parts, Dendrobium denneanum Kerr. spend 3 ~ 5 parts, Herba Cichorii 3 ~ 5 parts, Herba gentianae veitchiori 3 ~ 5 parts, 3 ~ 5 parts, Herba Swertiae Puniceae, Radix Angelicae Sinensis 3 ~ 8 parts, 3 ~ 8 parts, Poria, Herba Gynostemmatis 3 ~ 8 parts.
2. a kind of Chinese medicine formula for the treatment of cancer of pancreas as claimed in claim 1, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Herba Hedyotidis Diffusae 8 parts, Rhizoma Paridis 6 parts, Herba Salviae Chinensis 6 parts, Herba Selaginellae Doederleinii 6 parts, Folium Cycadis siamensis 7 parts, hedyotis tenelliflora Blume 5 parts, Herba Galii Teneri 5 parts, Radix Bupleuri 4 parts, Rhizoma Polygoni Cuspidati 4 parts, Rhizoma Cyperi (processed) 4 parts, Radix Scutellariae 4 parts, Dendrobium denneanum Kerr. spend 4 parts, Herba Cichorii 4 parts, Herba gentianae veitchiori 4 parts, 4 parts, Herba Swertiae Puniceae, Radix Angelicae Sinensis 5 parts, 5 parts, Poria, Herba Gynostemmatis 5 parts.
3. a preparation method for the Chinese medicine formula for the treatment of cancer of pancreas according to claim 1, is characterized in that step is as follows: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, there was not medical material 2 ~ 5cm, soaks 1 ~ 2 hour; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 20 ~ 40min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105582466A (en) * | 2015-12-31 | 2016-05-18 | 崔鹏 | Traditional Chinese medicine formula for treating liver cancer in early stage |
| CN105616873A (en) * | 2016-01-28 | 2016-06-01 | 陈西成 | Preparation for oncology department for treating pancreatic cancer and preparation method of preparation |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101670071A (en) * | 2009-09-25 | 2010-03-17 | 卢速江 | Traditional Chinese medicine preparation for treating cancer and preparation method thereof |
| CN102008685A (en) * | 2010-11-23 | 2011-04-13 | 高学哲 | Chinese medicinal powder for treating liver cancer, lung cancer and pancreatic cancer |
| CN103007202A (en) * | 2012-12-29 | 2013-04-03 | 王丽华 | Traditional Chinese medicine composition for treating pancreatic cancer |
-
2014
- 2014-12-30 CN CN201410850339.0A patent/CN104435520A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101670071A (en) * | 2009-09-25 | 2010-03-17 | 卢速江 | Traditional Chinese medicine preparation for treating cancer and preparation method thereof |
| CN102008685A (en) * | 2010-11-23 | 2011-04-13 | 高学哲 | Chinese medicinal powder for treating liver cancer, lung cancer and pancreatic cancer |
| CN103007202A (en) * | 2012-12-29 | 2013-04-03 | 王丽华 | Traditional Chinese medicine composition for treating pancreatic cancer |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105582466A (en) * | 2015-12-31 | 2016-05-18 | 崔鹏 | Traditional Chinese medicine formula for treating liver cancer in early stage |
| CN105616873A (en) * | 2016-01-28 | 2016-06-01 | 陈西成 | Preparation for oncology department for treating pancreatic cancer and preparation method of preparation |
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