CN105535597A - Compound medicine for treating gastroenteric tumor - Google Patents

Compound medicine for treating gastroenteric tumor Download PDF

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CN105535597A
CN105535597A CN201511003642.8A CN201511003642A CN105535597A CN 105535597 A CN105535597 A CN 105535597A CN 201511003642 A CN201511003642 A CN 201511003642A CN 105535597 A CN105535597 A CN 105535597A
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parts
radix
compound medicine
herba
tumor
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许琳
黄维清
马晓莹
孔庆暖
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Abstract

The invention discloses a compound medicine for treating gastroenteric tumor. The compound medicine is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 3 to 5 parts of radix ranunculi ternate, 4 to 6 parts of fructus polygoni orientalis, 3 to 5 parts of myrrh, 3 to 5 parts of herba rabdosiae, 3 to 5 parts of indigo naturalis, 5 to 8 parts of radix sophorae tonkinensis, 2 to 4 parts of radix platycodonis, 2 to 4 parts of cortex moutan, 6 to 10 parts of radix astragali, 6 to 8 parts of radix pseudostellariae, 1 to 3 parts of ganoderma, 5 to 8 parts of donkey-hide gelatin, 2 to 4 parts of rhizoma imperatae, 2 to 4 parts of corn stigma, 2 to 4 parts of herba abri, 2 to 3 parts of ossa draconis, 2 to 3 parts of herba lysimachiae, 2 to 3 parts of semen plantaginis, 2 to 3 parts of chingma abutilon seed, 2 to 4 parts of medulla junci, 1 to 3 parts of myrmeleontid larva and 2 to 4 parts of pollen typhae. According to the theories that traditional Chinese medicines have efficacies of strengthening and consolidating body resistance and promoting blood circulation to remove blood stasis, the compound medicine has the effects of tonifying the liver and kidney, reinforcing Qi and nourishing Yin, clearing away heat and toxic materials, and dissolving and relieving swelling, can be used for treating the gastroenteric tumor, treats both manifestation and root cause of disease, and is good in curative effect and quick in result.

Description

A kind of compound medicine for the treatment of gastroenteric tumor
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of compound medicine for the treatment of gastroenteric tumor.
Background technology
Gastroenteric tumor is optimum, the malignant tumor that betide stomach, small intestinal and large intestine.Clinical manifestation is different because of tumorigenic character and position.In general, benign tumor can be asymptomatic or symptom is very light.The early stage also non-evident sympton of some malignant tumor, thus impact diagnosis, treatment and prognosis.In gastroenteric tumor, the sickness rate of the intestinal tumor comparatively position such as esophagus, harmonization of the stomach large intestine is low.
Show as weight not wait stomachache, intestinal bleeding, intestinal obstruction, abdominal mass and lose weight.The symptom of malignant tumor is more, heavier, and carcinoid symptom is lighter or at all asymptomatic.Because gastrointestinal tumor lacks specific symptom and sign, therefore, early diagnosis is difficult to.
In China, gastroenteric tumor M & M is all in second, greatly threatens the life and health of the mankind.2012, national tumor population Standardized incidence rate was 146.87/10 ten thousand people, and wherein the gastric cancer of digestive system accounts for 12.67%, and intestinal cancer accounts for 10.30%, and hepatocarcinoma accounts for 10.04%, and the esophageal carcinoma accounts for 7.74%, the very severe state of its prevention and control situation.In China, for each patient, the expense of antitumor drug is all a white elephant.Except the chemotherapeutics of routine, humanized antibody drug, molecular targeted agents, novel targeted carrier medicament are all very expensive.And Chinese medicine is with a long history, determined curative effect, simultaneously cheap, be suitable for promoting.Therefore how to excavate the precious deposits of Chinese medicine at anti-tumor aspect, benefiting patient better, is the realistic problem that each work of Chinese medicine person faces.
Digestive tract tumor's tumor body increases rapidly at short notice, consume human body qi-blood-body fluid, make body and function day by day void decline, show as the pathological characters of pathogen being excessive but vital QI weak, now method for the treatment of when tonify deficiency righting is main; Except primary tumor, patient usually also there will be metastasis after surgery, therefore combines convergence removing toxic substances, and effect is unique.
Summary of the invention
The invention provides a kind of compound medicine for the treatment of gastroenteric tumor, according to TCM on tumor theory, nursed one's health by Chinese medicine, strengthening the body resistance, blood circulation promoting and blood stasis dispelling, from heat-clearing and toxic substances removing, except disease eliminating stagnation, promoting blood circulation to restore menstrual flow, dismission detumescence, adjustment treatment is carried out in the aspects such as supplementing QI and nourishing YIN, treatment gastroenteric tumor, to obtaining best therapeutic effect.
The compound medicine for the treatment of gastroenteric tumor of the present invention, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Radix Ranunculi Ternati 3-5 part, Fructus Polygoni Orientalis 4-6 part, Myrrha 3-5 part, Rabdosia rubescens 3-5 part, Indigo Naturalis 3-5 part, Radix Sophorae Tonkinensis 5-8 part, Radix Platycodonis 2-4 part, Cortex Moutan 2-4 part, Radix Astragali 6-10 part, Radix Pseudostellariae 6-8 part, Ganoderma 1-3 part, Colla Corii Asini 5-8 part, Rhizoma Imperatae 2-4 part, Stigma Maydis 2-4 part, Herba Abri 2-4 part, Os Draconis 2-3 part, Herba Lysimachiae 2-3 part, Semen Plantaginis 2-3 part, Semen Abutili 2-3 part, Medulla Junci 2-4 part, Spora Lygodii cattle 1-3 part, Pollen Typhae 2-4 part.
As preferably, prepare by following parts by weight: Radix Ranunculi Ternati 4 parts, Fructus Polygoni Orientalis 5 parts, Myrrha 3 parts, Rabdosia rubescens 4 parts, Indigo Naturalis 4 parts, Radix Sophorae Tonkinensis 6 parts, Radix Platycodonis 3 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, Radix Pseudostellariae 7 parts, Ganoderma 2 parts, 6 parts, Colla Corii Asini, Rhizoma Imperatae 3 parts, Stigma Maydis 3 parts, Herba Abri 3 parts, Os Draconis 2 parts, Herba Lysimachiae 2 parts, Semen Plantaginis 2 parts, Semen Abutili 2 parts, Medulla Junci 3 parts, Spora Lygodii cattle 2 parts, Pollen Typhae 3 parts.
Preparation method takes raw material by above-mentioned parts by weight, puts in marmite, then add drinking water, liquid level exceeds medical material 2-3cm, after intense fire is boiled, uses slow fire boiling instead after 50 minutes, pour out medicinal liquid, each decoction being taken warmly 200-300ml, every day early, evening twice is bfore meals.
Pharmacology analysis:
Radix Ranunculi Ternati: sweet, pungent, tepor.Return liver, lung meridian.Cure mainly scrofula sucutaneous nodule, furuncle, worm venom.
Fructus Polygoni Orientalis: have eliminating mass and relieving fullness eliminating stagnation, clearing away heat to alleviate pain function.For mass in the abdomen abdominal distention, quench one's thirst, stomachache.
Myrrha: cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There is the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation.
Rabdosia rubescens: have another name called Rabdosia rubescens, for Labiatae scented tea belongs to perennial herb or undershrub, undershrub.Nature and flavor are bitter, sweet, be slightly cold, and have good heat clearing away poison, promoting blood circulation and stopping pain, antibacterial, antitumor action.
Indigo Naturalis: be the dry pigment in dicotyledon medicine acanthaceous vegetable acanthaceous indigo, dicotyledon medicine leguminous plant Folium et Caulis Indigoferae Tinctoriae, dicotyledon medicine cruciferae isatis, careless Folium Isatidis or polygonaceae plant polygonum tinctorium ait. leaf.Nature and flavor are salty-cold, heat-clearing and toxic substances removing, removing heat from blood, speckle removing, purging liver-fire, arresting convulsion.Cure mainly: epidemic febrile disease intenseness of heat, macule, haematemesis, spitting of blood, pharyngalgia aphtha, pediatric epilepsy scared, skin ulcer are swollen, erysipelas, snake bite and insect sting.Herba Solani Nigri: Herb is used as medicine, can dissipating blood stasis for subsidence of swelling, heat-clearing and toxic substances removing.In we, get its evacuation of pus of invigorating blood circulation, anticancer swollen effect.
Radix Sophorae Tonkinensis: another name: three lobule Radix Sophorae Tonkinensiss, HUDOU lotus, have detumescence antitumaous effect.
Radix Platycodonis: another name burden flower, Radix Platycodonis, mitral flower, function cures mainly: lung qi dispersing, and sore-throat relieving eliminates the phlegm, evacuation of pus.Sore-throat relieving reduces phlegm, and leads the effect of medicine yang invigorating.
Cortex Moutan: toil, is slightly cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Compendium of Material Medica: " controlling the blood fire second of the three ten-day periods of the hot season, heat clearing away and restlessness relieving ".
The Radix Astragali: have enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Radix Pseudostellariae: sweet, micro-hardship, flat; Spleen, lung meridian; Air making-up and spleen enlivening, promoting the production of body fluid for nourishing the lung.
Colla Corii Asini: sweet, flat; Lung, liver, kidney channel; Enrich blood, YIN nourishing, lung moistening, hemostasis.
Rhizoma Imperatae: sweet in the mouth, cold.Removing heat from blood, hemostasis, heat clearing away, diuresis.Control calentura excessive thirst, spit blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.
Stigma Maydis: sweet in the mouth is put down, and has the effect such as inducing diuresis to remove edema, blood pressure lowering, hemostasis, function of gallbladder promoting.
Herba Abri: sweet and slightly bitter taste, cool in nature, returns liver, gallbladder, stomach warp.Clearing away heat-damp and promoting diuresis, eliminating stasis to stop pain.Main icterohepatitis, stomachache, rheumatic ostalgia, traumatic injury stasis of blood pain, mastalgia.
Os Draconis: sweet puckery; Flat; Nontoxic; Liver; Kidney; Large intestine channel; Tranquillizing the mind by relieving convulsion; Suppressing the hyperactive liver and subsiding YANG; Astringent or styptic treatment for spontaneous sweating; Convergence.Main infantile convulsion is demented; Severe palpitation; Insomnia forgetfulness; Have a dizzy spell; Spontaneous sweating; The seminal emission enuresis; Bleeding not during menses; Chronic diarrhea chronic dysentery; Ulcer does not close up and eczema for a long time.
Herba Lysimachiae: another name: Lysimachia christinae Hance, Drymoglossum subcordatum, Cui Pingcao, lotus bud grass, careless, the JINSUOSHI of Boiled small dumplings with pork, Herba Glechomae etc.There is the merit of clearing away heat and promoting diuresis, wind-expelling pain-stopping, hemostasia and promoting granulation, eliminating inflammation and expelling toxin, parasite killing.Can treating acute and chronic hepatitis, icterohepatitis, cholecystitis, nephritis, urinary system infection, tonsillitis, stomatitis and carbuncle furuncle treat poison, venom, acute mastitis, dysentery, malaria, pneumorrhagia etc.
Semen Plantaginis: sweet in the mouth, cold in nature.Return liver, kidney, lung, small intestine meridian.For the puckery pain of pyretic stranguria, edema distension, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.
Semen Abutili: sweet, cold, energy diuretic, laxation, stimulating milk secretion.
Medulla Junci: clearing heart fire, inducing diuresis for treating stranguria syndrome.Control gonorrhea, edema, dysuria, jaundice due to damp-heat, dysphoria and insomnia, the nocturnal fretfulness in infants, sore throat, wound.
Spora Lygodii cattle: pungent, salty, temperature.Return kidney, urinary bladder channel.Antipyretic, spasmolytic, eliminating stagnation, inducing diuresis for treating stranguria syndrome, changes furunculosis.For infantile hyperpyrexia, kidney and calculus of urethra, dysuria, scrofula, furuncle.
Pollen Typhae: sweet, flat.Return liver, pericardium channel.Hemostasis, blood stasis dispelling, treating stranguria.For spitting blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, blood strangury and dry pain.
Compound medicine of the present invention, hard masses softening and resolving, detumescence; Liver and kidney tonifying, Yin-nourishing and body fluid promoting; Detumescence and drawing out poison, heat-clearing and toxic substances removing; Activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving; All medicine compatibilities, liver and kidney tonifying, supplementing QI and nourishing YIN, heat-clearing and toxic substances removing, dismiss detumescence, treatment gastroenteric tumor, treating both the principal and secondary aspects of a disease, good effect, instant effect.
Outcome measure:
The main clinic symptoms of gastroenteric tumor has: performance weight not wait stomachache, intestinal bleeding, intestinal obstruction, abdominal mass and lose weight; The symptom of malignant tumor is more, heavier, and carcinoid symptom is lighter or at all asymptomatic; CT shows tumor body.
Effective: the disappearance of tumor body, sign and symptom are improved, diet and stool are normally.
Take a turn for the better: tumor body reduces, and sign and symptom are improved.
Invalid: sign and tumorous size such as front or tumor body increase.
Therapeutic outcome: patients with gastrointestinal carcinoma 100 example, takes medicine of the present invention, puts in marmite, then add drinking water, liquid level exceeds medical material 2-3cm, after intense fire is boiled, uses slow fire boiling instead after 50 minutes, pour out medicinal liquid, each decoction being taken warmly 200-300ml, every day early, late twice ante cibum decoction being taken warmly.Effective 75 examples, account for 75%, and take a turn for the better 12 examples, and account for 12%, effective percentage is 87%.
Attached several routine case is described further:
Case 1: Jiang, female, 50 years old, in October, 2012 examined, and conscious stool has some setbacks, falling inflation difficulty goes out, and proctoscopy finds 2.0 × 1.0 × 1.3cm size lump, is diagnosed as rectum tumor.Take medicine of the present invention, proctoscopy after 14 days, before lump is decreased to 1/2, falling inflation sense alleviates, and after continuing to take 14 days, recheck, lump disappears substantially, and symptom all disappears, and continues to take 14 days consolidate curative effect, and follow up a case by regular visits to 3 months, rehabilitation is normal.
Case 2: Wang, man, 35 years old, in July, 2014 examined, conscious uncomfortable, times of defecation increases band blood, is scanned by endorectal ultrasound, find lump, make pathologic finding, be diagnosed as rectum tumor, tumorous size 2.3 × 1.5 × 1.7cm, takes medicine of the present invention, and within 28 days, posterior tuberosity body is contracted to 1.5 × 0.9 × 1.0cm, times of defecation reduces, and remission, continues to take 21 days posterior tuberosity bodies and continue to be decreased to 0.3 × 0.3 × 0.2cm, after 14 days, recheck recovery from illness, follow up a case by regular visits to half a year without recurrence.
Detailed description of the invention
Embodiment 1
Radix Ranunculi Ternati 4 parts, Fructus Polygoni Orientalis 5 parts, Myrrha 3 parts, Rabdosia rubescens 4 parts, Indigo Naturalis 4 parts, Radix Sophorae Tonkinensis 6 parts, Radix Platycodonis 3 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, Radix Pseudostellariae 7 parts, Ganoderma 2 parts, 6 parts, Colla Corii Asini, Rhizoma Imperatae 3 parts, Stigma Maydis 3 parts, Herba Abri 3 parts, Os Draconis 2 parts, Herba Lysimachiae 2 parts, Semen Plantaginis 2 parts, Semen Abutili 2 parts, Medulla Junci 3 parts, Spora Lygodii cattle 2 parts, Pollen Typhae 3 parts.
Preparation method takes raw material by above-mentioned parts by weight, and put in marmite, then add drinking water, liquid level exceeds medical material 2.5cm, after intense fire is boiled, use slow fire boiling instead after 50 minutes, pour out medicinal liquid, each decoction being taken warmly 250ml, every day early, late twice ante cibum decoction being taken warmly, within 14 days, be a course for the treatment of.

Claims (2)

1. treat a compound medicine for gastroenteric tumor, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Radix Ranunculi Ternati 3-5 part, Fructus Polygoni Orientalis 4-6 part, Myrrha 3-5 part, Rabdosia rubescens 3-5 part, Indigo Naturalis 3-5 part, Radix Sophorae Tonkinensis 5-8 part, Radix Platycodonis 2-4 part, Cortex Moutan 2-4 part, Radix Astragali 6-10 part, Radix Pseudostellariae 6-8 part, Ganoderma 1-3 part, Colla Corii Asini 5-8 part, Rhizoma Imperatae 2-4 part, Stigma Maydis 2-4 part, Herba Abri 2-4 part, Os Draconis 2-3 part, Herba Lysimachiae 2-3 part, Semen Plantaginis 2-3 part, Semen Abutili 2-3 part, Medulla Junci 2-4 part, Spora Lygodii cattle 1-3 part, Pollen Typhae 2-4 part.
2. the compound medicine for the treatment of gastroenteric tumor according to claim 1, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Radix Ranunculi Ternati 4 parts, Fructus Polygoni Orientalis 5 parts, Myrrha 3 parts, Rabdosia rubescens 4 parts, Indigo Naturalis 4 parts, Radix Sophorae Tonkinensis 6 parts, Radix Platycodonis 3 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, Radix Pseudostellariae 7 parts, Ganoderma 2 parts, 6 parts, Colla Corii Asini, Rhizoma Imperatae 3 parts, Stigma Maydis 3 parts, Herba Abri 3 parts, Os Draconis 2 parts, Herba Lysimachiae 2 parts, Semen Plantaginis 2 parts, Semen Abutili 2 parts, Medulla Junci 3 parts, Spora Lygodii cattle 2 parts, Pollen Typhae 3 parts.
CN201511003642.8A 2015-12-28 2015-12-28 Compound medicine for treating gastroenteric tumor Pending CN105535597A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113122600A (en) * 2020-01-15 2021-07-16 四川森科制药有限公司 Method for extracting polypeptide of Shaniu and application of polypeptide of Shaniu as antineoplastic medicine

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491447A (en) * 2014-12-30 2015-04-08 潘振奎 Compound medicine for treating gastrointestinal tract tumors
CN104510835A (en) * 2014-12-23 2015-04-15 青岛市城阳区人民医院 Traditional Chinese medicinal formula for treating intestinal tumor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104510835A (en) * 2014-12-23 2015-04-15 青岛市城阳区人民医院 Traditional Chinese medicinal formula for treating intestinal tumor
CN104491447A (en) * 2014-12-30 2015-04-08 潘振奎 Compound medicine for treating gastrointestinal tract tumors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113122600A (en) * 2020-01-15 2021-07-16 四川森科制药有限公司 Method for extracting polypeptide of Shaniu and application of polypeptide of Shaniu as antineoplastic medicine

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