CN104491613A - Traditional Chinese medicine formula for treating gastrointestinal cancer - Google Patents

Traditional Chinese medicine formula for treating gastrointestinal cancer Download PDF

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Publication number
CN104491613A
CN104491613A CN201410763970.7A CN201410763970A CN104491613A CN 104491613 A CN104491613 A CN 104491613A CN 201410763970 A CN201410763970 A CN 201410763970A CN 104491613 A CN104491613 A CN 104491613A
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parts
herba
radix
chinese medicine
medicine formula
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金延春
王玉光
张华�
黄霞
王大鹏
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Affiliated Hospital of University of Qingdao
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Affiliated Hospital of University of Qingdao
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Abstract

The invention belongs to the technical field of traditional Chinese medicines and in particular relates to a traditional Chinese medicine formula for treating gastrointestinal cancer. The traditional Chinese medicine formula is prepared from the following medicinal raw materials in parts by weight: 8-10 parts of radix pseudostellariae, 8-10 parts of mythic fungus, 8-10 parts of donkey hide gelatin, 8-10 parts of cortex albiziae, 5-8 parts of radix trichosanthis, 5-8 parts of prunella vulgaris, 3-5 parts of cassia seed, 2-4 parts of common lophantherum herb, 2-4 parts of baikal skullcap root, 2-4 parts of cortex Phellodendri, 2-4 parts of fructus forsythia, 2-4 parts of dandelion, 5-8 parts of herba violae, 3-5 parts of rhizoma smilacis glabrae, 3-5 parts of Chinese lobelia herb, 10-13 parts of pseudobulbus cremastrae seu pleiones, 5-8 parts of uniflower swisscentaury root, 3-5 parts of oldenlandia diffusa, 3-5 parts of dahurian patrinia herb, 3-5 parts of Chinese dwarf cherry seed, 2-3 parts of allium macrostemon, 5-8 parts of circium japonicum, 1-2 parts of large blister beetle, 3-5 parts of algae and 3-5 parts of kelp. By virtue of nursing of herbal treatment, the traditional Chinese medicine formula is capable of strengthening and consolidating body, promoting blood circulation, removing blood stasis, clearing away heat and toxic materials, activating blood to promote menstruation, eliminating swelling, removing stasis, and nourishing qi and yin and is fast in effect and good in curative effect of treating the gastrointestinal cancer.

Description

A kind of Chinese medicine formula for the treatment of gastroenteric tumor
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine formula for the treatment of gastroenteric tumor.
Background technology
Gastroenteric tumor is optimum, the malignant tumor that betide stomach, small intestinal and large intestine.Clinical manifestation is different because of tumorigenic character and position.In general, benign tumor can be asymptomatic or symptom is very light.The early stage also non-evident sympton of some malignant tumor, thus impact diagnosis, treatment and prognosis.In gastroenteric tumor, the sickness rate of the intestinal tumor comparatively position such as esophagus, harmonization of the stomach large intestine is low.
Show as weight not wait stomachache, intestinal bleeding, intestinal obstruction, abdominal mass and lose weight.The symptom of malignant tumor is more, heavier, and carcinoid symptom is lighter or at all asymptomatic.Because gastrointestinal tumor lacks specific symptom and sign, therefore, early diagnosis is difficult to.
Owing to also not developing the medicine generally killing cancerous cell as spectrum antibacterial element now, so to most of tumor, cancer patient, first can only carry out resection operation, then cancerous cell is killed by X-ray therapy or chemotherapy, but these two kinds of methods also can kill normal human cell while killing cancerous cell, cause resistance and the immunity degradation of patient.For the side effect avoiding radiotherapy, chemotherapy is brought, during existing more way adopts, the therapy for treatment of cancer that combines of doctor trained in Western medicine.
Summary of the invention
The invention provides a kind of Chinese medicine formula for the treatment of gastroenteric tumor, according to TCM on tumor theory, nursed one's health by Chinese medicine, strengthening the body resistance, blood circulation promoting and blood stasis dispelling, adjustment treatment is carried out from aspects such as heat-clearing and toxic substances removing, promoting blood circulation to restore menstrual flow, dispersing swelling and dissipating binds, supplementing QI and nourishing YIN, treatment gastroenteric tumor, to obtaining best therapeutic effect.
Medicine of the present invention is that crude drug prepares by the Chinese medicine of following parts by weight:
Radix Pseudostellariae 8-10 part, Ganoderma 8-10 part, Colla Corii Asini 8-10 part, Cortex Albiziae 8-10 part, Radix Trichosanthis 5-8 part, Spica Prunellae 5-8 part, Semen Cassiae 3-5 part, Herba Lophatheri 2-4 part, Radix Scutellariae 2-4 part, Cortex Phellodendri 2-4 part, Fructus Forsythiae 2-4 part, Herba Taraxaci 2-4 part, Herba Violae 5-8 part, Rhizoma Smilacis Glabrae 3-5 part, Herba Lobeliae Chinensis 3-5 part, Pseudobulbus Cremastrae Seu Pleiones 10-13 part, Radix Rhapontici 5-8 part, Herba Hedyotidis Diffusae 3-5 part, Herba Patriniae 3-5 part, Semen Pruni 3-5 part, Bulbus Allii Macrostemonis 2-3 part, Radix Cirsii Japonici 5-8 part, Mylabris 1-2 part, Sargassum 3-5 part and Thallus Laminariae (Thallus Eckloniae) 3-5 part.
Chinese medicine formula of the present invention, is preferably by following portions by weight preparation: Radix Pseudostellariae 10 parts, Ganoderma 10 parts, 10 parts, Colla Corii Asini, Cortex Albiziae 10 parts, Radix Trichosanthis 6 parts, Spica Prunellae 6 parts, Semen Cassiae 4 parts, Herba Lophatheri 3 parts, Radix Scutellariae 3 parts, Cortex Phellodendri 3 parts, Fructus Forsythiae 3 parts, Herba Taraxaci 3 parts, Herba Violae 6 parts, Rhizoma Smilacis Glabrae 4 parts, Herba Lobeliae Chinensis 4 parts, Pseudobulbus Cremastrae Seu Pleiones 12 parts, Radix Rhapontici 6 parts, Herba Hedyotidis Diffusae 4 parts, Herba Patriniae 4 parts, Semen Pruni 4 parts, Bulbus Allii Macrostemonis 3 parts, Radix Cirsii Japonici 6 parts, Mylabris 2 parts, Sargassum 5 parts and Thallus Laminariae (Thallus Eckloniae) 5 parts.
By the concrete preparation method that above-mentioned each crude drug makes medicine of the present invention be:
Get above-mentioned raw material of Chinese medicine by above-mentioned parts by weight, Semen Pruni is smashed, mix homogeneously with other medical materials, clean, add distilled water immersion 2 hours; Decoct with water 2 times, each amount of water is 4 ~ 5 times of medical material weight, and decoct 2 ~ 3h, collecting decoction, obtains the Chinese medicine decoction for the treatment of gastroenteric tumor of the present invention.
Usage: be grown up each serving with 200mL, every day 2 times, decoction being taken warmly after meal.It within seven days, is a course for the treatment of; General gastrointestinal tumor 2-3 course for the treatment of; More than 4 courses for the treatment of of Severe gastrointestinal tumor; There are more than 5 courses for the treatment of of gastrointestinal cancer patients of pathological changes in gastrointestinal.
Pharmacology analysis:
Radix Trichosanthis: sweet, micro-hardship, to be slightly cold; Lung, stomach warp; Clearing away heat-fire; Promoting the production of body fluid to quench thirst; Detumescence and apocenosis.
Spica Prunellae: pungent, bitter, cold; Liver, gallbladder meridian; Clearing away heat-fire, improving eyesight, mass dissipating and swelling eliminating.
Rhizoma Dioscoreae: sweet, flat.Strengthening the spleen and stomach, lung benefiting kidney, tonify deficiency are won.Control anorexia and loose stool, asthenia, breath with cough, frequent micturition, leukorrhagia, to quench one's thirst.
Semen Cassiae: sweet, bitter, salty, is slightly cold; Enter liver, large intestine channel; Loosening bowel to relieve constipation.
Herba Lophatheri; Sweet, light cold.The heart, stomach, small intestine meridian; Clearing away heat-fire, relieving restlessness, diuresis.
Radix Scutellariae: bitter, cold.Lung, gallbladder, spleen, stomach, large intestine, heat clearing and damp drying, eliminating fire and detoxication, hemostasis.For carbuncle sore tumefacting virus.
Cortex Phellodendri: bitter, cold.Kidney, bladder, large intestine channel; Heat clearing and damp drying, eliminating fire and detoxication; For carbuncle sore tumefacting virus.
Fructus Forsythiae: bitter, be slightly cold, lung, the heart, small intestine meridian; Heat-clearing and toxic substances removing, the loose swollen knot that disappears, for carbuncle sore tumefacting virus, scrofula sucutaneous nodule.
Herba Taraxaci: bitter, sweet, cold; Liver, stomach warp; Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Herba Violae: bitter, acrid, cold; The heart, Liver Channel; Heat-clearing and toxic substances removing, removing heat from blood are subsided a swelling, for carbuncle sore tumefacting virus, acute mastitis acute appendicitis.
Rhizoma Smilacis Glabrae: sweet, light, flat; Liver, stomach warp; Removing toxic substances, dehumidifying, easing joint movement; For Fructus Myricae rubrae skin infection, limbs contracture, carbuncle sore tumefacting virus.
Herba Lobeliae Chinensis: pungent, flat; The heart, small intestinal, lung meridian; Heat-clearing and toxic substances removing, inducing diuresis to remove edema; For carbuncle sore tumefacting virus, snake bite and insect sting, abdominal distention edema.
Pseudobulbus Cremastrae Seu Pleiones: sweet, micro-pungent, cool; Liver, spleen channel; Heat-clearing and toxic substances removing, resolving carbuncle and expulsing boil; For carbuncle furunculosis, scrofula sucutaneous nodule, WEIJIA mass in the abdomen.
Radix Rhapontici: bitter, cold; Stomach warp; Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation; Swell and ache for acute mastitis, scrofula sore, arthralgia chiefly caused by damp pathogen contracture.
Herba Hedyotidis Diffusae: micro-hardship, sweet, cold; Stomach, large intestine, small intestine meridian; Heat-clearing and toxic substances removing, dampness removing are treating stranguria; For carbuncle sore tumefacting virus, laryngopharynx swelling and pain.
Herba Patriniae: pungent, bitter; Be slightly cold; Liver, stomach, large intestine channel; Heat-clearing and toxic substances removing, detumescence and apocenosis, stasis-dispelling and pain-killing, for acute appendicitis lung abscess, carbuncle sore tumefacting virus.
Semen Pruni: pungent, bitter, sweet, flat; Spleen, large intestine channel; Loosening bowel to relieve constipation, inducing diuresis to remove edema, for dryness of the intestine constipation, edema abdominal distention, beriberi edema.
Bulbus Allii Macrostemonis: acrid, bitter, warm; Lung, stomach, large intestine channel; Activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.
Radix Cirsii Japonici: sweet, bitter, cool; The heart, lung meridian; Cooling blood for hemostasis, dissipating blood stasis removing toxic substances, eliminating carbuncle.
Mylabris: pungent, hot, poisonous; Liver, kidney, stomach warp; Removing blood stasis, mass dissipating and swelling eliminating, counteracting toxic substances phagedenoma; Yong Yu WEIJIA, amenorrhea, carbuncle malignant boil, scrofula.
Sargassum: salty, cold; Liver, kidney channel; Eliminating phlegm and softening indurated mass, inducing diuresis to remove edema; For goiter, scrofula sucutaneous nodule, tumor.
Thallus Laminariae (Thallus Eckloniae): salty, cold; Liver, kidney channel; Eliminating phlegm and softening indurated mass, inducing diuresis to remove edema; For goiter, scrofula sucutaneous nodule, tumor.
Cortex Albiziae: sweet, flat; The heart, lung, Liver Channel; Resolving stagnation for tranquilization, promoting blood circulation and detumescence; For malaise, insomnia and dreamful sleep, lung abscess, sore and toxic.
Ganoderma: sweet, flat; The heart, lung, kidney, Liver Channel; To calm the nerves tonify deficiency.
Radix Pseudostellariae: sweet, micro-hardship, flat; Spleen, lung meridian; Air making-up and spleen enlivening, promoting the production of body fluid for nourishing the lung.
Colla Corii Asini: sweet, flat; Lung, liver, kidney channel; Enrich blood, YIN nourishing, lung moistening, hemostasis.
Theory of Chinese medical science is thought, the generation of tumor, development and healthy energy virtual loss, spirit disorder of emotion, exopathogen is invaded, the factors such as dietetic nutrition is unbalance are directly related, in Chinese medicine formula of the present invention, and Ganoderma, Colla Corii Asini, Radix Pseudostellariae and Cortex Albiziae air making-up and spleen enlivening, YIN nourishing of enriching blood, promoting the production of body fluid for nourishing the lung, play the effect of strengthening the body resistance, Cortex Albiziae also has Huoxue San " and to swell, eliminate effect of sore and toxic; Fructus Forsythiae, Cortex Phellodendri, Herba Lobeliae Chinensis, Spica Prunellae, Radix Scutellariae, Herba Taraxaci, Herba Violae, Radix Rhapontici, Herba Hedyotidis Diffusae bitter in the mouth are cold in nature, can heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling; Mylabris is pungent, hot, greatly poison, treating the poisonous disease with poisonous drugs, and removing blood stasis, removing food stagnancy, removing blood stasis disappear knot; Radix Trichosanthis, Rhizoma Smilacis Glabrae, Pseudobulbus Cremastrae Seu Pleiones, Radix Cirsii Japonici, Herba Patriniae cooling blood for hemostasis, loose swollen evacuation of pus, dampness removing is treating stranguria; Bulbus Allii Macrostemonis activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving; All medicine compatibilities, act synergistically on gastrointestinal diseased region, loose swollen disappear knot, removing blood stasis, and nourishing YIN and supplementing blood, invigorating spleen and kidney, improve immunity of organisms, treatment gastroenteric tumor, and quick acting, cures patient, the misery of reduction of patient.
Outcome measure:
The main clinic symptoms of gastroenteric tumor has: performance weight not wait stomachache, intestinal bleeding, intestinal obstruction, abdominal mass and lose weight; The symptom of malignant tumor is more, heavier, and carcinoid symptom is lighter or at all asymptomatic; CT shows tumor body.
Remarkable: tumor body obviously reduces, sign and symptom are improved, diet and stool normal.
Take a turn for the better: tumor body reduces, and sign and symptom are improved.
Invalid: sign and tumorous size such as front or tumor body increase.
Therapeutic outcome: gastric tumor patient 75 example, intestinal canal tumour patient 64 example, amounts to 139 examples, and gastric tumor patient tumor body obviously reduces 63 examples, and take a turn for the better 7 examples, and intestinal canal tumour patient tumor body obviously reduces 53 examples, and take a turn for the better 4 examples, and total effective rate is 92%.
Attached several routine case is described further:
Case 1: together certain, man, 53 years old, in December, 2013 is examined, and readme stool has some setbacks, falling inflation difficulty goes out, lower abdomen random thoughts pain, slightly have blood in stool, proctoscopy finds 2.1 × 1.7 × 1.6cm size lump, is diagnosed as rectum tumor, takes medicine of the present invention, proctoscopy after two courses for the treatment of, before lump is decreased to 1/2, falling inflation sense alleviates, after continuing to take two courses for the treatment of, recheck, lump disappears substantially, continues to take a course for the treatment of, and symptom all disappears, defecation is normal, proctoscopy lump disappears, and follow up a case by regular visits to three months, rehabilitation is normal.
Case 2: Zheng, female, 44 years old, in March, 2014 examines, conscious uncomfortable, times of defecation increases band blood, pain, scanned by endorectal ultrasound, find lump, make pathologic finding, be diagnosed as rectum tumor, tumorous size 4.2X5.3X3.5cm, take medicine of the present invention, phenomenon of having blood in stool after the course for the treatment of is improved, pain relief, three the course for the treatment of sky posterior tuberosity body be contracted to 2.7X2.9X1.7cm, times of defecation reduces, remission, after continuing to take two day after tomorrow course for the treatment of, recheck tumor body to continue to reduce, leave hospital, take medicine of the present invention so far, follow up a case by regular visits to without recurrence.
Detailed description of the invention
Embodiment 1:
The Chinese medicine formula of the treatment gastroenteric tumor of the present embodiment, formulated by the raw material of Chinese medicine of following parts by weight: Radix Pseudostellariae 10 parts, Ganoderma 10 parts, 10 parts, Colla Corii Asini, Cortex Albiziae 10 parts, Radix Trichosanthis 6 parts, Spica Prunellae 6 parts, Semen Cassiae 4 parts, Herba Lophatheri 3 parts, Radix Scutellariae 3 parts, Cortex Phellodendri 3 parts, Fructus Forsythiae 3 parts, Herba Taraxaci 3 parts, Herba Violae 6 parts, Rhizoma Smilacis Glabrae 4 parts, Herba Lobeliae Chinensis 4 parts, Pseudobulbus Cremastrae Seu Pleiones 12 parts, Radix Rhapontici 6 parts, Herba Hedyotidis Diffusae 4 parts, Herba Patriniae 4 parts, Semen Pruni 4 parts, Bulbus Allii Macrostemonis 3 parts, Radix Cirsii Japonici 6 parts, Mylabris 1 part, Sargassum 5 parts and Thallus Laminariae (Thallus Eckloniae) 5 parts.
Chinese medicine formula of the present invention, prepare as follows:
Get above-mentioned raw material of Chinese medicine by above-mentioned parts by weight, Semen Pruni is smashed, mix homogeneously with other medical materials, clean, add distilled water immersion 2 hours; Decoct with water 2 times, each amount of water is 4 ~ 5 times of medical material weight, and decoct 2 ~ 3h, collecting decoction, obtains the Chinese medicine decoction for the treatment of gastroenteric tumor of the present invention.
Usage: be grown up each serving with 200mL, every day 2 times, decoction being taken warmly after meal.It within seven days, is a course for the treatment of; General gastrointestinal tumor 2-3 course for the treatment of; More than 4 courses for the treatment of of Severe gastrointestinal tumor; There are more than 5 courses for the treatment of of gastrointestinal cancer patients of pathological changes in gastrointestinal.

Claims (2)

1. treat the Chinese medicine formula of gastroenteric tumor for one kind, it is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Radix Pseudostellariae 8-10 part, Ganoderma 8-10 part, Colla Corii Asini 8-10 part, Cortex Albiziae 8-10 part, Radix Trichosanthis 5-8 part, Spica Prunellae 5-8 part, Semen Cassiae 3-5 part, Herba Lophatheri 2-4 part, Radix Scutellariae 2-4 part, Cortex Phellodendri 2-4 part, Fructus Forsythiae 2-4 part, Herba Taraxaci 2-4 part, Herba Violae 5-8 part, Rhizoma Smilacis Glabrae 3-5 part, Herba Lobeliae Chinensis 3-5 part, Pseudobulbus Cremastrae Seu Pleiones 10-13 part, Radix Rhapontici 5-8 part, Herba Hedyotidis Diffusae 3-5 part, Herba Patriniae 3-5 part, Semen Pruni 3-5 part, Bulbus Allii Macrostemonis 2-3 part, Radix Cirsii Japonici 5-8 part, Mylabris 1-2 part, Sargassum 3-5 part and Thallus Laminariae (Thallus Eckloniae) 3-5 part.
2. the Chinese medicine formula for the treatment of gastroenteric tumor according to claim 1, it is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Radix Pseudostellariae 10 parts, Ganoderma 10 parts, 10 parts, Colla Corii Asini, Cortex Albiziae 10 parts, Radix Trichosanthis 6 parts, Spica Prunellae 6 parts, Semen Cassiae 4 parts, Herba Lophatheri 3 parts, Radix Scutellariae 3 parts, Cortex Phellodendri 3 parts, Fructus Forsythiae 3 parts, Herba Taraxaci 3 parts, Herba Violae 6 parts, Rhizoma Smilacis Glabrae 4 parts, Herba Lobeliae Chinensis 4 parts, Pseudobulbus Cremastrae Seu Pleiones 12 parts, Radix Rhapontici 6 parts, Herba Hedyotidis Diffusae 4 parts, Herba Patriniae 4 parts, Semen Pruni 4 parts, Bulbus Allii Macrostemonis 3 parts, Radix Cirsii Japonici 6 parts, Mylabris 1 part, Sargassum 5 parts and Thallus Laminariae (Thallus Eckloniae) 5 parts.
CN201410763970.7A 2014-12-11 2014-12-11 Traditional Chinese medicine formula for treating gastrointestinal cancer Pending CN104491613A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105535677A (en) * 2015-12-28 2016-05-04 许琳 Compound medicine for treating gastrointestinal tumor

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102772745A (en) * 2012-08-21 2012-11-14 卢速江 Chinese medicinal preparation for treating cancer and preparation method thereof
CN103908635A (en) * 2014-04-03 2014-07-09 荆振海 Traditional Chinese medicine pill for treating colonic carcinoid and preparation method of traditional Chinese medicine pill

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102772745A (en) * 2012-08-21 2012-11-14 卢速江 Chinese medicinal preparation for treating cancer and preparation method thereof
CN103908635A (en) * 2014-04-03 2014-07-09 荆振海 Traditional Chinese medicine pill for treating colonic carcinoid and preparation method of traditional Chinese medicine pill

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105535677A (en) * 2015-12-28 2016-05-04 许琳 Compound medicine for treating gastrointestinal tumor

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