CN104840904A - Traditional Chinese medicine composition for treating hyperplasia of mammary glands - Google Patents
Traditional Chinese medicine composition for treating hyperplasia of mammary glands Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating hyperplasia of mammary glands. The traditional Chinese medicine composition is prepared from the ingredients in parts by weight: bupleurum root, nutgrass galingale rhizome, green tangerine peel, angelica sinensis, chuanxiong rhizome, salvia miltiorrhiza, manis pentadactyla Linnaeus, rhizoma zedoariae, raw oyster shell, radix astragali, poria cocos, seaweed, herba leonuri, rhizoma sparganii, deer horn, dried old orange peel, peach kernel, thunberg fritillary bulb, selfheal spike, frankincense, codonopsis pilosula, tangerine seed, glycyrrhiza uralensis, rhubarb root, cowherb seed, safflowers, radix curcumae, luffa cylindrica, radix asparagi, dandelions, rhizoma pleionis, curculigo orchioides, evodia, epimedium, myrrha, litchi seed and radix isatidis. The traditional Chinese medicine composition provided by the invention is used for treating diseases such as hyperplasia of mammary glands, benign tumor of mammary glands and hysteromyoma, is remarkable in effect and is free of toxic or side effects, the effective rate of treatment reaches 95%, and recurrence is difficult.
Description
Technical field
The invention belongs to Chinese medicine capsule preparation technique field, be specifically related to a kind ofly be used for the treatment of the medicine of cyclomastopathy and the preparation method of this medicine thereof, this Chinese medicine composition is used for the treatment of cyclomastopathy, mammary gland benign tumor, the diseases such as hysteromyoma.
Background technology
Cyclomastopathy is the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of mastopathy.This sick sickness rate was in the trend risen year by year in the last few years, and the age also more and more becomes younger.Cyclomastopathy is also known as mammary dysplasia, fibrocystic disease of breast, a kind of disease of comprehensive various clinical disease, comprise that cyst is principal mode (simple cyst), adenopathy is principal mode, fibroadenoma spline structure is principal mode, intraductal papillomatosis is principal mode (not comprising isolatism and multiple intraductal papilloma), atypical hyperplasia etc.Clinical data it is generally acknowledged that primary disease has five kinds of basic lesion, i.e. cyst formation, Epithelial hyperplasia, medium and small duct papilloma disease, glandular tube gonadopathy (blind pipe gonadopathy), epithelial cell metaplasia apocrine, as long as 2 kinds in finding wherein 3 kinds or major lesions, can primary disease be diagnosed as.Cyclomastopathy is neither inflammation, and also non-tumor, outstanding behaviours is mastalgia and lump clinically.
Cystic hyperplasia of breast is a clinical stage in a kind of of breast proliferative lesions or hyperplastic process, cyst, Epithelial hyperplasia, tubular adenopathy, the life of profuse sweating adenization, papillomatosis etc. are shown as because its pathological tissue changes, be summarised as the pathological change that ductal ectasia encystation and Epithelial hyperplasia two kinds have Major Clinical sign, commonly encountered diseases and the frequently-occurring disease of period of duration women, its sickness rate accounts for the women of child-bearing age's about 40%, accounting for all mastotic 75%, is modal cystic hyperplasia of breast.Along with the quickening of modern society's rhythm of life, its sickness rate is in rising trend.Epidemiologic data shows, schooling and hold a high place in society, Menarcheal Age early, the above the average age for marriage just women that pregnant, low tire produces and menopause is slower is the group of people at high risk of primary disease.
Doctor trained in Western medicine is understood fully at present not yet completely to the understanding of the cause and onset of disease mechanism of cyclomastopathy; but its morbidity is mainly because the viewpoint of endocrine hormone imbalance is by Most scholars is generally acknowledged; therefore; theoretical according to the etiology of sexual hormone disturbance; the treatment of cyclomastopathy mainly regulates ovarian endocrine tend to normal or block hormonal action target spot, alleviates clinical symptoms.Clinical many employing endocrine therapy schemes and operative therapy, also have the auxiliary treatment such as vitamin, Operand, diuretic in addition.Cyclomastopathy belongs to endocrine system disease, and itself is without the indication of operative treatment, and operative treatment damage surface is large, cures the symptoms, not the disease, easily recurs again, therefore do not advise that cyclomastopathy patient applies.In a word, western medical treatment primary disease is many just to be alleviated or improves symptom, and side effect is large, more disorderly by it improper hormone in vivo balance that instead can make, and is difficult to the Histological change after making cyclomastopathy and is restored.
The traditional Chinese medical science is attributed to " nodules of the breast " category cyclomastopathy.Doctor's Chen Shigong is pointed out: " nodules of the breast is nodule in the breast, shape as ball ovum, or pendant recast pain, its core with susceptible to anger growth and decline, this nodules of the breast." traditional Chinese medical science thinks, breast and liver spleen kidney three through and to rush wantonly two arteries and veins relations the closest, depressed emotion, angry easy impairing the liver usually; excessive thinking is the impairment of the spleen then; cause liver to lose bar and reach, transverse invasion of hyperactive liver-QI violates taste, dysfunction of the spleen in transportation; ascending or descending movement of vital Qi mistake department; qi depression to blood stasis, the turbid interior life of expectorant, gathers and is core; pent up in breast, breast meridian and vessels obstruction is obstructed and cause mastalgia.Kidney is the source of vital essence of five ZANG-organs, kidney qiization life menses, and menses excites punching to appoint, and a lower uterus is appointed in punching, upper even breast, the QI and blood that punching is appointed, upper behavior breast, lower behavior warp.If deficiency of kidney-QI, then Chong and Ren channel disorder, stagnation of QI-blood, the long-pending stasis of blood is gathered becomes caking in breast.Chong and Ren channel disorder is the morbidity basis of this disease, and depression of liver-QI, the expectorant blood coagulation stasis of blood are the mark of morbidity, and Chinese medicine has its distinctive feature on treatment cyclomastopathy, provides many means for treating primary disease at present
There is considerable patient's attention degree inadequate after having suffered from cyclomastopathy, slowly do not go to a doctor or only demand and alleviate mastalgia symptom, and be unaware of the potential danger of cyclomastopathy---i.e., mammary gland benign tumor can be there is or malignant change occurs in the long-term protracted course of disease of small part cyclomastopathy.
Cyclomastopathy annoyings a lot of women, now conventional medicine is based on depressed liver-energy dispersing and QI regulating blood stasis-eliminating and stagnation-dissipating, but treatment time is very long, and the sensation of curing latter about 2 months distending pain of the breast will occur again, next is exactly that long-term steroid class medicine is treated, generally pain can only occur immediately after temporary relief of symptoms withdrawal, and the function of Long-term taking medicine to the organ such as stomach, liver, kidney of people has very large side effect.
The medicines such as it is generally little gold plaque that the medicine of current treatment cyclomastopathy and mastadenoma takes, danazol, ease pill take, but there are some shortcomings, and such as lump maximum gauge reduces less than 1/2nd, and mastalgia alleviates; Mass reduction more than 1/2nd, mastalgia does not alleviate, DeGrain, can not reach the object that lump disappears completely, and after drug withdrawal, the state of an illness can recur.
The present invention is according to theory of Chinese medical science, and excavate traditional ancient prescription and form, described Chinese medicine composition can be worked in coordination with mutually, and therapeutic effect is remarkable, has no side effect, effectively can treat cyclomastopathy, eliminates lump, and treatment cyclomastopathy effective percentage can reach more than 90%.In addition, Chinese medicine composition of the present invention can also play blood circulation promoting and blood stasis dispelling, liver-smoothing, qi-regulating, can for hysteromyoma, and ovarian cyst plays effective therapeutical effect.
Summary of the invention
An object of the present invention is to provide and is a kind ofly used for the treatment of the medicine of cyclomastopathy and the preparation method of this medicine, and this Chinese medicine composition is used for the treatment of cyclomastopathy, mammary gland benign tumor, the diseases such as hysteromyoma.
The present invention realizes by the following technical solutions: a kind of Chinese medicine composition for the treatment of cyclomastopathy, comprise each component of following weight portion: Radix Bupleuri 15-20 part, Rhizoma Cyperi 10-15 part, Pericarpium Citri Reticulatae Viride 10-12 part, Radix Angelicae Sinensis 15-18 part, Rhizoma Chuanxiong 10-12 part, Radix Salviae Miltiorrhizae 15-20 part, Squama Manis 10-15 part, Rhizoma Curcumae 10-15 part, Concha Ostreae 15-30 part, Radix Astragali 15-25 part, Poria 10-25 part, Sargassum 9-20 part, Herba Leonuri 10-20 part, Rhizoma Sparganii 9-15 part, Cornu Cervi 6-12 part, Pericarpium Citri Reticulatae 8-15 divides, Semen Persicae 3-8 part, Bulbus Fritillariae Thunbergii 5-15 part, Spica Prunellae 6-18 part, Olibanum 8-20 part, Radix Codonopsis 10-15 part, Semen Citri Reticulatae 10-15 part, Radix Glycyrrhizae 10-20 part, Radix Et Rhizoma Rhei 10-15 part, king does not stay 5-15 part, Flos Carthami 5-15 part, Radix Curcumae 10-15 part, Retinervus Luffae Fructus 3-8 part, Radix Asparagi 10-15 part, Herba Taraxaci 10-15 part, Pseudobulbus cremastrae seu pleiones 10-15 part, Rhizoma Curculiginis 2-8 part, Fructus Evodiae 5-9 part, Herba Epimedii 3-8 part, Myrrha 3-12 part, Semen Litchi 3-6 part, Radix Isatidis 3-5 part.
Further, Chinese medicine composition of the present invention comprises each component of following weight portion: Radix Bupleuri 15 parts, Rhizoma Cyperi 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 10 parts, Radix Salviae Miltiorrhizae 15 parts, Squama Manis 10 parts, Rhizoma Curcumae 10 parts, Concha Ostreae 15 parts, the Radix Astragali 15 parts, 10 parts, Poria, Sargassum 9 parts, Herba Leonuri 10 parts, Rhizoma Sparganii 9 parts, 6 parts, Cornu Cervi, Pericarpium Citri Reticulatae 8 points, 3 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 5 parts, Spica Prunellae 6 parts, Olibanum 8 parts, Radix Codonopsis 10 parts, Semen Citri Reticulatae 10 parts, 10 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 parts, king does not stay 5 parts, 5 parts, Flos Carthami, Radix Curcumae 10 parts, Retinervus Luffae Fructus 3 parts, Radix Asparagi 10 parts, Herba Taraxaci 10 parts, Pseudobulbus cremastrae seu pleiones 10 parts, Rhizoma Curculiginis 2 parts, Fructus Evodiae 5 parts, Herba Epimedii 3 parts, Myrrha 3 parts, Semen Litchi 3 parts, Radix Isatidis 3 parts.
Further, Chinese medicine composition of the present invention comprises each component of following weight portion: Radix Bupleuri 18 parts, Rhizoma Cyperi 12 parts, 11 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 10 parts, Radix Salviae Miltiorrhizae 16 parts, Squama Manis 12 parts, Rhizoma Curcumae 12 parts, Concha Ostreae 20 parts, the Radix Astragali 20 parts, 20 parts, Poria, Sargassum 15 parts, Herba Leonuri 15 parts, Rhizoma Sparganii 12 parts, 10 parts, Cornu Cervi, Pericarpium Citri Reticulatae 12 parts, 5 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 10 parts, Spica Prunellae 12 parts, Olibanum 12 parts, Radix Codonopsis 12 parts, Semen Citri Reticulatae 12 parts, 15 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 parts, king does not stay 10 parts, 10 parts, Flos Carthami, Radix Curcumae 13 parts, Retinervus Luffae Fructus 5 parts, Radix Asparagi 13 parts, Herba Taraxaci 10 parts, Pseudobulbus cremastrae seu pleiones 10 parts, Rhizoma Curculiginis 5 parts, Fructus Evodiae 8 parts, Herba Epimedii 5 parts, Myrrha 3 parts, Semen Litchi 5 parts, Radix Isatidis 5 parts.
Further, Chinese medicine composition of the present invention comprises each component Radix Bupleuri 20 parts of following weight portion, Rhizoma Cyperi 15 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 18 parts, Rhizoma Chuanxiong 12 parts, Radix Salviae Miltiorrhizae 20 parts, Squama Manis 15 parts, Rhizoma Curcumae 15 parts, Concha Ostreae 30 parts, the Radix Astragali 25 parts, 25 parts, Poria, Sargassum 20 parts, Herba Leonuri 20 parts, Rhizoma Sparganii 15 parts, 12 parts, Cornu Cervi, Pericarpium Citri Reticulatae 15 points, 8 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 15 parts, Spica Prunellae 18 parts, Olibanum 20 parts, Radix Codonopsis 15 parts, Semen Citri Reticulatae 15 parts, 20 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 parts, king does not stay 15 parts, 15 parts, Flos Carthami, Radix Curcumae 15 parts, Retinervus Luffae Fructus 8 parts, Radix Asparagi 15 parts, Herba Taraxaci 15 parts, Pseudobulbus cremastrae seu pleiones 15 parts, Rhizoma Curculiginis 8 parts, Fructus Evodiae 9 parts, Herba Epimedii 8 parts, Myrrha 12 parts, Semen Litchi 6 parts, Radix Isatidis 5 parts.
Radix Bupleuri: reconciling superficies and interior, soothing the liver, yang invigorating, for cold, fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse.
Rhizoma Cyperi: acrid in the mouth, micro-hardship, micro-sweet, property is put down; Return liver, spleen, tri-jiao channel; Cure mainly promoting QI circulation for relieving depression, menstruction regulating and pain relieving.
Pericarpium Citri Reticulatae Viride: temperature, acrid in the mouth; Enter liver, gallbladder meridian; Soothing the liver dispelling the stagnated QI, eliminating stagnation expectorant; Control breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction block.
Radix Angelicae Sinensis: sweet in the mouth, enriches blood and invigorates blood circulation, and regulating menstruation relieves the pain, loosening bowel to relieve constipation, and for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, cold in blood is suffered from abdominal pain, dryness of the intestine constipation, rheumatalgia, traumatic injury.
Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping, changes and becomes silted up, dispersing the stagnated live-QI to relieve the stagnation of QI.
Radix Salviae Miltiorrhizae: invigorate blood circulation logical, removing heat from blood is subsided a swelling, and clear away heart-fire relieving restlessness, promoting blood circulation to remove blood stasis, sedation-analgesia, menoxenia, dysmenorrhea, metrorrhagia, mastitis, relieving mammary gland gall.
Squama Manis: the routed carbuncle of detumescence, searches wind active, stimulating milk secretion of stimulating the menstrual flow; Control carbuncle skin ulcer kind, anemofrigid-damp arthralgia, amenorrhea, galactostasis.
Rhizoma Curcumae: bitter in the mouth is pungent, warm in nature; Circulation of qi promoting, removing blood stasis, removing food stagnancy, pain relieving; Control trusted subordinate's distending pain, hundred abdominal masss, gather, and dyspepsia does not disappear, and women's blood stasis amenorrhea, traumatic injury is had a pain.
Concha Ostreae: salty, is slightly cold.Suppressing the hyperactive liver and subsiding YANG; Tranquillization with heavy prescription; Hard masses softening and resolving, restrains astringent or styptic treatment for spontaneous sweating; Cure mainly vertigo and tinnitus; Palpitation with fear insomnia, scrofula goiter, lump in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia.
The Radix Astragali: exterior deficiency hyperhidrosis, night sweat due to yin deficiency, yang-energy is weak, and the deficiency of vital energy is weak.
Poria: sweet light is flat; Enter the heart, spleen, lung meridian; Eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.
Sargassum: salty in the mouth, cold in nature, has effect of heat clearing away, hard masses softening and resolving; Deficiency and coldness of spleen and stomach person avoids edible.
Herba Leonuri: promoting blood flow to regulate menstruation, inducing diuresis to remove edema, heat-clearing and toxic substances removing, for menoxenia, amenorrhea of stimulating the menstrual flow, lochiorrhea, puerperal, blood closed.
Rhizoma Sparganii: acrid in the mouth, hardship, property is put down; Return liver, spleen channel controls lump in the abdomen, gather, distending pain over the hypochondrium, food stagnation distending pain, dysmenorrhea, amenorrhea, postnatal blood stasis is suffered from abdominal pain, traumatic injury; Cough due to lung-heat controlled by mongolian medicine, asthma abundant expectoration, liver-heat, arteries and veins heat, the hot hectic fever due to YIN-deficiency of consumptive disease.
Cornu Cervi: warming the kidney to activate YANG, astringing to arrest bleeding, treatment deficiency of kidney-QI, good merchantable brand of enriching blood.
Pericarpium Citri Reticulatae: return lung, spleen channel; Cure mainly regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Semen Persicae: silt of invigorating blood circulation, quench the thirst and relieving asthma, intestine moistening, amenorrhea is stimulated the menstrual flow, pain in the lung enterodynia.
Bulbus Fritillariae Thunbergii: bitter in the mouth, cold in nature.Return lung, heart channel.There is removing heat-phlegm, the effects such as powder detoxifcation.Control cough due to pathogenic wind-heat, lung abscess sore throat, scrofula, sore swollen toxin.。
Spica Prunellae: liver heat removing eliminating stagnation, diuresis, antibacterial, blood pressure lowering, comfortable, resolving depression.
Olibanum: blood-activating and qi-promoting pain relieving, detumescence life, resistance of becoming silted up puerperal, amenorrhea of stimulating the menstrual flow.
Radix Codonopsis: using tonifying Qi reinforcing lungs, supplementing QI for promoting the production of body fluid, anti-hypoxia, defying age, strengthens body immunity, anemia etc.
Semen Citri Reticulatae: promoting QI to circulate and dispersing the agglomeration of the pathogens pain relieving, antiinflammatory.
Radix Glycyrrhizae: property is sweet, flat, GUIXIN, lung, spleen, stomach warp, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Radix Et Rhizoma Rhei: heat and toxic materials clearing away, eliminating fire and detoxication, blood circulation promoting and blood stasis dispelling, lets out clearly damp and hot.
Semen Vaccariae: another name Wang Buliu, Vaccaria segetalis.For the dry seed of pinkwort Vaccaria segetalis, there is promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain, expedite the emergence of the function of stimulating milk secretion; Cure mainly menoxenia, agalactosis, difficult labour, the diseases such as carbuncle furunculosis.
Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, for amenorrhea, dysmenorrhea, lochia ， mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Radix Curcumae: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice etc., are usually used in amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge.
Retinervus Luffae Fructus: may be used for treating mastitis, urethritis, uterine prolapse, arthralgia.
Radix Asparagi: nourshing Yin and drynsessmoistening prescription, cough-relieving of relieving inflammation or internal heat, deep blue treats mammary neoplasms, cyclomastopathy, pain in the lung, laryngopharynx swelling and pain.
Herba Taraxaci: heat-clearing and toxic substances removing, medicinal powder for relieving pain is tied, and antifungal, antitumor, to hyperpyrexia, mastalgia has good effect.
Pseudobulbus Cremastrae Seu Pleiones: heat-clearing and toxic substances removing, dissipating phlegm and resolving masses, pain is swollen treats poison, snake bite and insect sting.
Rhizoma Curculiginis: reinforcing the kidney and supporting YANG, benefiting essence-blood, bone and muscle strengthening, promoting the circulation of blood is subsided a swelling, and the kidney warming sun is strong, dispels cold-damp.
Fructus Evodiae: dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, the disturbance of lower legs due to pathogenic cold and dampness, multiple logical through row, abdominal distention.
Herba Epimedii: kidney invigorating and YANG supporting, expelling wind and removing dampness, dribbling urination, muscles and bones contraction is anxious, and cough, rheumatic arthralgia, extremity are meciless.
Myrrha: breast abdomen becomes silted up bitterly, and amenorrhea, stimulates the menstrual flow, traumatic injury, pain is swollen, promoting blood circulation and stopping pain, detumescence and promoting granulation.
Semen Litchi: promoting QI to circulate and dispersing the agglomeration of the pathogens, pain relieving of dispeling cold, stomachache, controls pricking caused by the stagnation of QI and blood, small intestine-QI, pained.
Radix Isatidis: resisting pathogenic microbes, anticoagulant, removing toxic substances, detumescence, antiallergic.
The method of Chinese medicine composition of the present invention, comprises the following steps:
(1) Radix Bupleuri is taken by weight, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Squama Manis, Rhizoma Curcumae, Concha Ostreae, the Radix Astragali, Poria, Sargassum, Herba Leonuri, Rhizoma Sparganii, Cornu Cervi, Pericarpium Citri Reticulatae, Semen Persicae, Bulbus Fritillariae Thunbergii, Spica Prunellae, Olibanum, Radix Codonopsis, Semen Citri Reticulatae, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Wang Buliu, Flos Carthami, Radix Curcumae, Retinervus Luffae Fructus, Radix Asparagi, Herba Taraxaci, Pseudobulbus cremastrae seu pleiones, Rhizoma Curculiginis, Fructus Evodiae, Herba Epimedii, Myrrha, Semen Litchi, each crude drug of Radix Isatidis;
(2) by each crude drug mix homogeneously soak by water, merge decoction liquor, filter, collect filtrate, the pH value of adjustment filtrate, be then condensed into extractum, add adjuvant or the excipient of preparations shaping, preparations shaping, to obtain final product; Hydrochloric acid wherein can be adopted to adjust the pH value of filtrate.
The method of Chinese medicine composition of the present invention, can also adopt following preparation method:
(1), by weight Radix Bupleuri is taken, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Squama Manis, Rhizoma Curcumae, Concha Ostreae, the Radix Astragali, Poria, Sargassum, Herba Leonuri, Rhizoma Sparganii, Cornu Cervi, Pericarpium Citri Reticulatae, Semen Persicae, Bulbus Fritillariae Thunbergii, Spica Prunellae, Olibanum, Radix Codonopsis, Semen Citri Reticulatae, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Wang Buliu, Flos Carthami, Radix Curcumae, Retinervus Luffae Fructus, Radix Asparagi, Herba Taraxaci, Pseudobulbus cremastrae seu pleiones, Rhizoma Curculiginis, Fructus Evodiae, Herba Epimedii, Myrrha, Semen Litchi, each crude drug of Radix Isatidis;
(2) by each crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merges decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, room temperature is static, adds ethanol and reaches ethanol contend 60-80%, hold over night, get supernatant, reclaim ethanol, the pH value of adjustment filtrate, then extractum is condensed into, add adjuvant or the excipient of preparations shaping, preparations shaping, to obtain final product.
The method of Chinese medicine composition of the present invention, can also adopt following preparation method:
(1) each crude drug is taken by described weight proportion;
(2) through screening, washing, dries, parching to brown, pulverizes, sieves, then take Mel by medicated powder and Mel 1:1, add water, put in pot to boil and endure slowly, plunder offscum, by moisture content consumption to dripping a sweet Cheng Zhu, being cooled to 80-100 DEG C, then segmenting with above-mentioned medicine and stir evenly mediation, knead into honeyed pill, after dry honeyed pill shape medicine.
Chinese medicine composition of the present invention, can be prepared into any one acceptable oral drug preparation clinically; Preferably, described oral drug preparation is pill, powder, granule, capsule, tablet, drop pill or oral liquid.
Be about 2-3 month the full course for the treatment of, every day two doses, drink the state of an illness and determine.Points for attention: give up alcohol, alepidote, egg, vinegar, Fructus Capsici, Bulbus Allii, Herba Alii fistulosi.Beneficial effect of the present invention is: have no side effect, dispersing the stagnated live-QI to relieve the stagnation of QI, and carry middle gas, removing food stagnancy is stagnant, and curative effect is good, the time is short, dosage is little, expense is low, not easily recurs.
Detailed description of the invention
Embodiment 1
Take Radix Bupleuri 20 parts, Rhizoma Cyperi 15 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 18 parts, Rhizoma Chuanxiong 12 parts, Radix Salviae Miltiorrhizae 20 parts, Squama Manis 15 parts, Rhizoma Curcumae 15 parts, Concha Ostreae 30 parts, the Radix Astragali 25 parts, 25 parts, Poria, Sargassum 20 parts, Herba Leonuri 20 parts, Rhizoma Sparganii 15 parts, 12 parts, Cornu Cervi, Pericarpium Citri Reticulatae 15 points, 8 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 15 parts, Spica Prunellae 18 parts, Olibanum 20 parts, Radix Codonopsis 15 parts, Semen Citri Reticulatae 15 parts, 20 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 parts, king does not stay 15 parts, 15 parts, Flos Carthami, Radix Curcumae 15 parts, Retinervus Luffae Fructus 8 parts, Radix Asparagi 15 parts, Herba Taraxaci 15 parts, Pseudobulbus cremastrae seu pleiones 15 parts, Rhizoma Curculiginis 8 parts, Fructus Evodiae 9 parts, Herba Epimedii 8 parts, Myrrha 12 parts, Semen Litchi 6 parts, Radix Isatidis 5 parts, by each crude drug mix homogeneously soak by water, merge decoction liquor, filter, collect filtrate, with the pH value of hydrochloric acid adjustment filtrate, then extractum is condensed into, add adjuvant or the excipient of preparations shaping, preparations shaping, obtain.
Embodiment 2
Take Radix Bupleuri 20 parts, Rhizoma Cyperi 15 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 18 parts, Rhizoma Chuanxiong 12 parts, Radix Salviae Miltiorrhizae 20 parts, Squama Manis 15 parts, Rhizoma Curcumae 15 parts, Concha Ostreae 30 parts, the Radix Astragali 25 parts, 25 parts, Poria, Sargassum 20 parts, Herba Leonuri 20 parts, Rhizoma Sparganii 15 parts, 12 parts, Cornu Cervi, Pericarpium Citri Reticulatae 15 points, 8 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 15 parts, Spica Prunellae 18 parts, Olibanum 20 parts, Radix Codonopsis 15 parts, Semen Citri Reticulatae 15 parts, 20 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 parts, king does not stay 15 parts, 15 parts, Flos Carthami, Radix Curcumae 15 parts, Retinervus Luffae Fructus 8 parts, Radix Asparagi 15 parts, Herba Taraxaci 15 parts, Pseudobulbus cremastrae seu pleiones 15 parts, Rhizoma Curculiginis 8 parts, Fructus Evodiae 9 parts, Herba Epimedii 8 parts, Myrrha 12 parts, Semen Litchi 6 parts, Radix Isatidis 5 parts, by each crude drug mix homogeneously soak by water, merge decoction liquor, filter, collect filtrate, be condensed into extractum, add adjuvant or the excipient of preparations shaping, preparations shaping, obtain.
Embodiment 3
Take Radix Bupleuri 18 parts, Rhizoma Cyperi 12 parts, 11 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 10 parts, Radix Salviae Miltiorrhizae 16 parts, Squama Manis 12 parts, Rhizoma Curcumae 12 parts, Concha Ostreae 20 parts, the Radix Astragali 20 parts, 20 parts, Poria, Sargassum 15 parts, Herba Leonuri 15 parts, Rhizoma Sparganii 12 parts, 10 parts, Cornu Cervi, Pericarpium Citri Reticulatae 12 parts, 5 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 10 parts, Spica Prunellae 12 parts, Olibanum 12 parts, Radix Codonopsis 12 parts, Semen Citri Reticulatae 12 parts, 15 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 parts, king does not stay 10 parts, 10 parts, Flos Carthami, Radix Curcumae 13 parts, Retinervus Luffae Fructus 5 parts, Radix Asparagi 13 parts, Herba Taraxaci 10 parts, Pseudobulbus cremastrae seu pleiones 10 parts, Rhizoma Curculiginis 5 parts, Fructus Evodiae 8 parts, Herba Epimedii 5 parts, Myrrha 3 parts, Semen Litchi 5 parts, Radix Isatidis 5 parts, by each crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merge decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, room temperature is static, add ethanol and reach ethanol contend 60-80%, hold over night, get supernatant, reclaim ethanol, then extractum is condensed into, add adjuvant or the excipient of preparations shaping, preparations shaping, obtain.
Embodiment 4:
Take Radix Bupleuri 15 parts, Rhizoma Cyperi 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 10 parts, Radix Salviae Miltiorrhizae 15 parts, Squama Manis 10 parts, Rhizoma Curcumae 10 parts, Concha Ostreae 15 parts, the Radix Astragali 15 parts, 10 parts, Poria, Sargassum 9 parts, Herba Leonuri 10 parts, Rhizoma Sparganii 9 parts, 6 parts, Cornu Cervi, Pericarpium Citri Reticulatae 8 points, 3 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 5 parts, Spica Prunellae 6 parts, Olibanum 8 parts, Radix Codonopsis 10 parts, Semen Citri Reticulatae 10 parts, 10 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 parts, king does not stay 5 parts, 5 parts, Flos Carthami, Radix Curcumae 10 parts, Retinervus Luffae Fructus 3 parts, Radix Asparagi 10 parts, Herba Taraxaci 10 parts, Pseudobulbus cremastrae seu pleiones 10 parts, Rhizoma Curculiginis 2 parts, Fructus Evodiae 5 parts, Herba Epimedii 3 parts, Myrrha 3 parts, Semen Litchi 3 parts, Radix Isatidis 3 parts, by each crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merge decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, room temperature is static, add ethanol and reach ethanol contend 60-80%, hold over night, get supernatant, reclaim ethanol, the pH value of adjustment filtrate, then extractum is condensed into, add adjuvant or the excipient of preparations shaping, preparations shaping, obtain.
Embodiment 5:
Take Radix Bupleuri 18 parts, Rhizoma Cyperi 12 parts, 11 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 10 parts, Radix Salviae Miltiorrhizae 16 parts, Squama Manis 12 parts, Rhizoma Curcumae 12 parts, Concha Ostreae 20 parts, the Radix Astragali 20 parts, 20 parts, Poria, Sargassum 15 parts, Herba Leonuri 15 parts, Rhizoma Sparganii 12 parts, 10 parts, Cornu Cervi, Pericarpium Citri Reticulatae 12 parts, 5 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 10 parts, Spica Prunellae 12 parts, Olibanum 12 parts, Radix Codonopsis 12 parts, Semen Citri Reticulatae 12 parts, 15 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 parts, king does not stay 10 parts, 10 parts, Flos Carthami, Radix Curcumae 13 parts, Retinervus Luffae Fructus 5 parts, Radix Asparagi 13 parts, Herba Taraxaci 10 parts, Pseudobulbus cremastrae seu pleiones 10 parts, Rhizoma Curculiginis 5 parts, Fructus Evodiae 8 parts, Herba Epimedii 5 parts, Myrrha 3 parts, Semen Litchi 5 parts, Radix Isatidis 5 parts, through screening, washing, dry, parching to brown, pulverize, sieve, then Mel is taken by medicated powder and Mel 1:1, add water, put in pot to boil and endure slowly, plunder offscum, by moisture content consumption to dripping sweet Cheng Zhu, be cooled to 80-100 DEG C, segment with above-mentioned medicine again and stir evenly mediation, knead into honeyed pill, after dry honeyed pill shape medicine.
Clinical data
400 examples are female patient, minimum 20 years old of age, maximum 55 years old, wherein 22-29 year 60 examples, 30-40 year 260 examples, more than 40 years old 80 is routine, the course of disease 3 months-10 years is not etc., ill 121 examples of monolayer, ill 279 examples of bilateral, hypertrophy lump is in the different quadrant distribution of mammary gland, more common with the outside upper quadrant of two breast, cyclomastopathy 190 example, fibroplasia 80 example, cystic hyperplasia 10 example.
Therapeutic Method: the pharmaceutical composition for the treatment of cyclomastopathy prepared by all selected patients daily two, two panels or this invention of two balls, point morning and evening warm water takes, and one after each meal 10th is a course for the treatment of.
Criterion of therapeutical effect
Cure: clinical symptom disappearance, lump is eliminated; Effective: transference cure, more than mass reduction l/2; Effective: lump deliquescing, reduce less than l/2, and still have tenderness, premenstruum and tired rear mastalgia comparatively before alleviate; Invalid: unchanged before and after treatment.
Therapeutic outcome
Cure 286 examples, effective 40 examples, effective 60 examples, invalid 14 examples, total effective rate 95%.
Model case:
Case 1, Zhao, female, 30 years old, ill 5 years, two mammary swelling pain during each menstrual onset, and enclosed mass has increase, through after pain relief or disappearance, still can not disappear although enclosed mass reduces.Resemble the enclosed mass that all differs in size outside left and right breast, hard in matter, smooth surface, mobility is good, and tenderness is obvious.Bilateral breast skin is normal, and nipple is without depression and discharge.Ultrasound diagnosis: bilateral breast lobule fibroid hypertrophy.Ru Fang Molybdenum target x-ray checks: two cyclomastopathy.Gonadal hormone inspection is abnormal.Through taking 2 courses for the treatment of of medicine composite for curing of the present invention, there is not distending pain of the breast in menstrual onset menstrual period, go on 3 courses for the treatment of, all disease knowing are removed, and follows up a case by regular visits to and do not recur in 2 years.
Case 2, Lee, female, 40 years old, ill 8 years, before menstrual onset, feel that bimastism has lump, and has the trend of increase afterwards, both sides distending pain of the breast between moon paramenstrum, occasionally have sharp, and lump in breast increase, sensation of oppression over the chest with shortness of breath with the fluctuation of breast feelings will, cystic cyclomastopathy is diagnosed as through examination in hospital, fully recover after taking 3 courses for the treatment of of Chinese medicine composition of the present invention, adhere to again 3 courses for the treatment of of taking medicine, follow up a case by regular visits to and do not recur for 3 years.
Case 3: Zhang, female, 46 years old, mammary gland pain 1 year half on the left of primary symptom, nearly half a year increases the weight of, mammary gland outside upper quadrant in left side can touch enclosed mass, and matter is hard, menoxenia, take 1 course for the treatment of of Chinese medicine of the present invention, distending pain obviously alleviates, continue to take 2 the course for the treatment of symptom disappear completely, follow up a case by regular visits to 3 years after adhering to taking 2 courses for the treatment of without recurrence.
With clinical data, the specific embodiment of the present invention is described although above-mentioned in conjunction with the embodiments; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various amendment or distortion that creative work can make still within protection scope of the present invention.
Claims (10)
1. treat the Chinese medicine composition of cyclomastopathy for one kind, comprise each component of following weight portion: Radix Bupleuri 15-20 part, Rhizoma Cyperi 10-15 part, Pericarpium Citri Reticulatae Viride 10-12 part, Radix Angelicae Sinensis 15-18 part, Rhizoma Chuanxiong 10-12 part, Radix Salviae Miltiorrhizae 15-20 part, Squama Manis 10-15 part, Rhizoma Curcumae 10-15 part, Concha Ostreae 15-30 part, Radix Astragali 15-25 part, Poria 10-25 part, Sargassum 9-20 part, Herba Leonuri 10-20 part, Rhizoma Sparganii 9-15 part, Cornu Cervi 6-12 part, Pericarpium Citri Reticulatae 8-15 part, Semen Persicae 3-8 part, Bulbus Fritillariae Thunbergii 5-15 part, Spica Prunellae 6-18 part, Olibanum 8-20 part, Radix Codonopsis 10-15 part, Semen Citri Reticulatae 10-15 part, Radix Glycyrrhizae 10-20 part, Radix Et Rhizoma Rhei 10-15 part, king does not stay 5-15 part, Flos Carthami 5-15 part, Radix Curcumae 10-15 part, Retinervus Luffae Fructus 3-8 part, Radix Asparagi 10-15 part, Herba Taraxaci 10-15 part.
2. Chinese medicine composition as claimed in claim 1, is characterized in that, also comprise Pseudobulbus cremastrae seu pleiones 10-15 part, Rhizoma Curculiginis 2-8 part, Fructus Evodiae 5-9 part, Herba Epimedii 3-8 part, Myrrha 3-12 part, Semen Litchi 3-6 part, Radix Isatidis 3-5 part.
3. Chinese medicine composition as claimed in claim 2, it is characterized in that: each ingredients weight parts is Radix Bupleuri 15 parts, Rhizoma Cyperi 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 10 parts, Radix Salviae Miltiorrhizae 15 parts, Squama Manis 10 parts, Rhizoma Curcumae 10 parts, Concha Ostreae 15 parts, the Radix Astragali 15 parts, 10 parts, Poria, Sargassum 9 parts, Herba Leonuri 10 parts, Rhizoma Sparganii 9 parts, 6 parts, Cornu Cervi, Pericarpium Citri Reticulatae 8 points, 3 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 5 parts, Spica Prunellae 6 parts, Olibanum 8 parts, Radix Codonopsis 10 parts, Semen Citri Reticulatae 10 parts, 10 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 parts, king does not stay 5 parts, 5 parts, Flos Carthami, Radix Curcumae 10 parts, Retinervus Luffae Fructus 3 parts, Radix Asparagi 10 parts, Herba Taraxaci 10 parts, Pseudobulbus cremastrae seu pleiones 10 parts, Rhizoma Curculiginis 2 parts, Fructus Evodiae 5 parts, Herba Epimedii 3 parts, Myrrha 3 parts, Semen Litchi 3 parts, Radix Isatidis 3 parts.
4. according to Chinese medicine composition according to claim 2, it is characterized in that, each ingredients weight parts is Radix Bupleuri 18 parts, Rhizoma Cyperi 12 parts, 11 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 10 parts, Radix Salviae Miltiorrhizae 16 parts, Squama Manis 12 parts, Rhizoma Curcumae 12 parts, Concha Ostreae 20 parts, the Radix Astragali 20 parts, 20 parts, Poria, Sargassum 15 parts, Herba Leonuri 15 parts, Rhizoma Sparganii 12 parts, 10 parts, Cornu Cervi, Pericarpium Citri Reticulatae 12 parts, 5 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 10 parts, Spica Prunellae 12 parts, Olibanum 12 parts, Radix Codonopsis 12 parts, Semen Citri Reticulatae 12 parts, 15 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 parts, king does not stay 10 parts, 10 parts, Flos Carthami, Radix Curcumae 13 parts, Retinervus Luffae Fructus 5 parts, Radix Asparagi 13 parts, Herba Taraxaci 10 parts, Pseudobulbus cremastrae seu pleiones 10 parts, Rhizoma Curculiginis 5 parts, Fructus Evodiae 8 parts, Herba Epimedii 5 parts, Myrrha 3 parts, Semen Litchi 5 parts, Radix Isatidis 5 parts.
5. according to Chinese medicine composition according to claim 2, it is characterized in that, each ingredients weight parts is Radix Bupleuri 20 parts, Rhizoma Cyperi 15 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis 18 parts, Rhizoma Chuanxiong 12 parts, Radix Salviae Miltiorrhizae 20 parts, Squama Manis 15 parts, Rhizoma Curcumae 15 parts, Concha Ostreae 30 parts, the Radix Astragali 25 parts, 25 parts, Poria, Sargassum 20 parts, Herba Leonuri 20 parts, Rhizoma Sparganii 15 parts, 12 parts, Cornu Cervi, Pericarpium Citri Reticulatae 15 points, 8 parts, Semen Persicae, Bulbus Fritillariae Thunbergii 15 parts, Spica Prunellae 18 parts, Olibanum 20 parts, Radix Codonopsis 15 parts, Semen Citri Reticulatae 15 parts, 20 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 parts, king does not stay 15 parts, 15 parts, Flos Carthami, Radix Curcumae 15 parts, Retinervus Luffae Fructus 8 parts, Radix Asparagi 15 parts, Herba Taraxaci 15 parts, Pseudobulbus cremastrae seu pleiones 15 parts, Rhizoma Curculiginis 8 parts, Fructus Evodiae 9 parts, Herba Epimedii 8 parts, Myrrha 12 parts, Semen Litchi 6 parts, Radix Isatidis 5 parts.
6. according to the Chinese medicine composition described in any one of claim 1-5, it is characterized in that: be prepared into any one acceptable oral drug preparation clinically; Preferably, described oral drug preparation is pill, powder, granule, capsule, tablet, drop pill or oral liquid.
7. prepare a method for Chinese medicine composition described in any one of claim 1-5, comprise the following steps:
(1), by weight Radix Bupleuri is taken, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Squama Manis, Rhizoma Curcumae, Concha Ostreae, the Radix Astragali, Poria, Sargassum, Herba Leonuri, Rhizoma Sparganii, Cornu Cervi, Pericarpium Citri Reticulatae, Semen Persicae, Bulbus Fritillariae Thunbergii, Spica Prunellae, Olibanum, Radix Codonopsis, Semen Citri Reticulatae, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Wang Buliu, Flos Carthami, Radix Curcumae, Retinervus Luffae Fructus, Radix Asparagi, Herba Taraxaci, Pseudobulbus cremastrae seu pleiones, Rhizoma Curculiginis, Fructus Evodiae, Herba Epimedii, Myrrha, Semen Litchi, each crude drug of Radix Isatidis;
(2) by each crude drug mix homogeneously soak by water, merge decoction liquor, filter, collect filtrate, with the pH value of hydrochloric acid adjustment filtrate, be then condensed into extractum, add adjuvant or the excipient of preparations shaping, preparations shaping, to obtain final product.
8. prepare a method for Chinese medicine composition described in any one of claim 1-5, comprise the following steps:
(1), by weight Radix Bupleuri is taken, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Squama Manis, Rhizoma Curcumae, Concha Ostreae, the Radix Astragali, Poria, Sargassum, Herba Leonuri, Rhizoma Sparganii, Cornu Cervi, Pericarpium Citri Reticulatae, Semen Persicae, Bulbus Fritillariae Thunbergii, Spica Prunellae, Olibanum, Radix Codonopsis, Semen Citri Reticulatae, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Wang Buliu, Flos Carthami, Radix Curcumae, Retinervus Luffae Fructus, Radix Asparagi, Herba Taraxaci, Pseudobulbus cremastrae seu pleiones, Rhizoma Curculiginis, Fructus Evodiae, Herba Epimedii, Myrrha, Semen Litchi, each crude drug of Radix Isatidis;
(2) by each crude drug mix homogeneously 6-10 times of soak by water 3 times, each 2-4 hour, merges decoction liquor, filter, collect filtrate, filtrate is concentrated into relative density at 60-80 DEG C when being 1.2-1.3g/ml, room temperature is static, adds ethanol and reaches ethanol contend 60-80%, hold over night, get supernatant, reclaim ethanol, the pH value of adjustment filtrate, then extractum is condensed into, add adjuvant or the excipient of preparations shaping, preparations shaping, to obtain final product.
9. prepare a method for Chinese medicine composition described in any one of claim 1-5, comprise the following steps:
(1) each crude drug is taken by described weight proportion;
(2) through screening, washing, dries, parching to brown, pulverizes, sieves, then take Mel by medicated powder and Mel 1:1, add water, put in pot to boil and endure slowly, plunder offscum, by moisture content consumption to dripping a sweet Cheng Zhu, being cooled to 80-100 DEG C, then segmenting with above-mentioned medicine and stir evenly mediation, knead into honeyed pill, after dry honeyed pill shape medicine.
10. the purposes of Chinese medicine composition described in any one of claim 1-5 in preparation treatment cyclomastopathy.
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| CN105362852A (en) * | 2015-12-28 | 2016-03-02 | 青岛华之草医药科技有限公司 | Traditional Chinese medicine composition for treating hyperplasia of mammary glands |
| CN105362851A (en) * | 2015-12-28 | 2016-03-02 | 青岛华之草医药科技有限公司 | Method for preparing traditional Chinese medicine composition for treating hyperplasia of mammary glands |
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| CN105920545A (en) * | 2016-06-29 | 2016-09-07 | 唐会杰 | Chinese medicinal composition for treating breast hyperplasia and preparation method thereof |
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| CN106177104A (en) * | 2016-08-31 | 2016-12-07 | 王兰英 | A kind of external application medical ointment coordinating physiological period conditioning and treating cyclomastopathy |
| CN106362095A (en) * | 2016-11-01 | 2017-02-01 | 尹艳玲 | Traditional Chinese medicine composition capable of treating breast hyperplasia |
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| CN106692878A (en) * | 2017-01-19 | 2017-05-24 | 张应芹 | Medicine for treating mammary gland hyperplasia and preparation method of medicine |
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| CN105362852A (en) * | 2015-12-28 | 2016-03-02 | 青岛华之草医药科技有限公司 | Traditional Chinese medicine composition for treating hyperplasia of mammary glands |
| CN105362851A (en) * | 2015-12-28 | 2016-03-02 | 青岛华之草医药科技有限公司 | Method for preparing traditional Chinese medicine composition for treating hyperplasia of mammary glands |
| CN105902642A (en) * | 2016-06-24 | 2016-08-31 | 马月鲤 | Pharmaceutical composition having breast health care function, and preparation method and use of pharmaceutical composition |
| CN105920545A (en) * | 2016-06-29 | 2016-09-07 | 唐会杰 | Chinese medicinal composition for treating breast hyperplasia and preparation method thereof |
| CN106075026A (en) * | 2016-07-08 | 2016-11-09 | 丁鸿磊 | A kind of Chinese medicine treating cyclomastopathy and preparation method thereof |
| CN106177104A (en) * | 2016-08-31 | 2016-12-07 | 王兰英 | A kind of external application medical ointment coordinating physiological period conditioning and treating cyclomastopathy |
| CN106362095A (en) * | 2016-11-01 | 2017-02-01 | 尹艳玲 | Traditional Chinese medicine composition capable of treating breast hyperplasia |
| CN106729370A (en) * | 2016-12-05 | 2017-05-31 | 通渭县中医医院 | A kind of Chinese medicine composition for treating Chong and Ren channel disorder type mastoproliferation |
| CN106692878A (en) * | 2017-01-19 | 2017-05-24 | 张应芹 | Medicine for treating mammary gland hyperplasia and preparation method of medicine |
| CN106620550A (en) * | 2017-03-23 | 2017-05-10 | 李晶晶 | Medicine for treating hyperplasia of mammary glands and preparation method thereof |
| CN109276684A (en) * | 2017-07-19 | 2019-01-29 | 邓泽潭 | A kind of oral traditional Chinese medicine composition for treating the proliferation of mammary gland |
| CN107496839A (en) * | 2017-09-15 | 2017-12-22 | 王纯凤 | A kind of Chinese medicine composition for treating mammary gland disease |
| CN113633740A (en) * | 2021-08-23 | 2021-11-12 | 湖南中医药大学 | Traditional Chinese medicine composition, traditional Chinese medicine preparation and traditional Chinese medicine product for treating breast nodules |
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Application publication date: 20150819 |