CN102988543A - Traditional Chinese medicine for treating hyperplasia of mammary glands and preparation method of traditional Chinese medicine - Google Patents

Traditional Chinese medicine for treating hyperplasia of mammary glands and preparation method of traditional Chinese medicine Download PDF

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CN102988543A
CN102988543A CN2012104770938A CN201210477093A CN102988543A CN 102988543 A CN102988543 A CN 102988543A CN 2012104770938 A CN2012104770938 A CN 2012104770938A CN 201210477093 A CN201210477093 A CN 201210477093A CN 102988543 A CN102988543 A CN 102988543A
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chinese medicine
traditional chinese
vinegar
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CN102988543B (en
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陈延
陈松旺
闫保勋
屈荣华
贺永亮
鲁超
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ZHENGZHOU RUILONG PHARMACEUTICAL CO Ltd
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Abstract

The invention provides a traditional Chinese medicine for treating hyperplasia of mammary glands and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine provided by the invention comprises the following components in parts by weight: 10-30 parts of uncooked oyster, 10-30 parts of Salvia miltiorrhiza, 10-30 parts of seaweeds, 10-30 parts of radix astragali, 5-15 parts of dandelion, 1-5 parts of vinegar frankincense, 1-5 parts of vinegar myrrh, 1-5 parts of fired cowherb seeds, 1-5 parts of green tangerine peels and 0.005-0.02 part of muschus. The preparation method of the traditional Chinese medicine comprises the following steps of: mixing and crushing the crude drugs to prepare powder and bottling. The traditional Chinese medicine provided by the invention has the effects of smoothing the liver and regulating vital energy, resolving hard lump, activating blood and dissolving stasis, supplementing qi and promoting the production of body fluid and activating meridians to stop pain. The traditional Chinese medicine is used for treating hyperplasia of mammary glands and is also capable of regulating menstrual disorder and promoting breast to be vigorous and graceful, convenient to use and low in price.

Description

A kind of Chinese medicine for the treatment of cyclomastopathy and preparation method thereof
Technical field
The present invention relates to field of medicaments, be specifically related to a kind of Chinese medicine for the treatment of cyclomastopathy and preparation method thereof.
Background technology
Cyclomastopathy refers to breast epithelium and proliferation of fibrous tissue, mammary gland tissue conduit and lobules of mammary gland degeneration structurally and the growth of carrying out property connective tissue, and its pathogenic factor mainly is because the endocrine hormone imbalance.Show according to investigations 70 ~ 85% adult female in various degree cyclomastopathy is arranged.Show that according to latest survey cyclomastopathy has become the modal mastopathy problem of women, not only sickness rate rises gradually, and the morbidity crowd more and more becomes younger.
The medicine for the treatment of cyclomastopathy has a lot, but mostly is greatly oral administration, and taking dose is large, and the medication cycle is long, and the financial burden that brings to the patient is large.
Summary of the invention
For the problem of above-mentioned existence, the object of the present invention is to provide a kind of Chinese medicine that is used for the treatment of cyclomastopathy.
Technical scheme of the present invention is that a kind of Chinese medicine that is used for the treatment of cyclomastopathy respectively forms weight portion and is: Concha Ostreae 10-30 part, Radix Salviae Miltiorrhizae 10-30 part, Sargassum 10-30 part, Radix Astragali 10-30 part, Herba Taraxaci 5-15 part, Olibanum (processed with vinegar) 1-5 part, Myrrha (processed with vinegar) 1-5 part, Semen Vaccariae (parched) 1-5 part, Pericarpium Citri Reticulatae Viride 1-5 part and artificial Moschus 0.005-0.02 part.
The optimum formula of the Chinese medicine of described treatment cyclomastopathy is: 20 parts of Concha Ostreae, 20 parts of Radix Salviae Miltiorrhizaes, 20 parts of Sargassums, 20 parts of the Radixs Astragali, 10 parts of Herba Taraxacis, 3 parts of Olibanum (processed with vinegar), 3 parts of Myrrha (processed with vinegar), 3 parts of Semen Vaccariae (parched)s, 3 parts on Pericarpium Citri Reticulatae Viride, 0.01 part of artificial Moschus.
Simultaneously, the present invention also aims to provide a kind of preparation method that is used for the treatment of the Chinese medicine of cyclomastopathy.
Preparation method is: Concha Ostreae, Radix Salviae Miltiorrhizae, Sargassum, the Radix Astragali, Herba Taraxaci, Olibanum (processed with vinegar), Myrrha (processed with vinegar), Semen Vaccariae (parched), Pericarpium Citri Reticulatae Viride and artificial Moschus by weight co-grinding, are made powder, and in the bottle of packing into, every bottle 3 gram.
Usage and dosage is: medicated powder is put into umbilicus, become pasty state with the vinegar moistening, use the sponge sheet gland, use immobilization with adhesive tape again, get final product.Each one bottle, according to state of an illness weight, change once every 2-3 day, 8-12 time is a course for the treatment of.
The effect of each raw material components is among the present invention:
Concha Ostreae: contain calcium carbonate, calcium phosphate and calcium sulfate, and trace element and the several amino acids such as cupric, zinc, ferrum, manganese, strontium, chromium, salty in the mouth and puckery, slightly cool in nature can softening and eliminating sputum, and the kind scrofula that disappears is ended singultus, controlling nocturnal emission with astringent drugs gas;
Radix Salviae Miltiorrhizae: bitter in the mouth, cold in nature and slow, can removing heat from blood and promoting blood circulation, again can the heat clearing away eliminating carbuncle, can promoting tissue regeneration by removing blood stasis and just do not hinder kind regulating menstruation water;
Sargassum: the beginning is stated from Shennong's Herbal, and " main goiter gas is examined under the neck, broken eliminating stagnation gas, the hard gas of Yong Zhong mass in the abdomen, up and down ring in the abdomen, lower 12 edema ", this product is salty energy relaxing the bowels with lubricant drugs herein, the cold diversion that can expel the heat-evil, and the heavily fortified point of the goiter that can disappear tuberculosis is poly-, makes pathogen from urinating;
The Radix Astragali: sweet in the mouth, tepor mainly contains glycoside, polysaccharide, flavone, aminoacid and trace element.In this product, can play the effect of spleen invigorating invigorating middle warmer, ascending up spleen-Qi and Yang, promoting pus discharge and tissue regeneration strengthening;
Herba Taraxaci: bitter, sweet, cold, can removing summer-heat burning hot poison is evil, and the gas that again can drop-down stagnates is the good merchantable brand of eliminating carbuncle eliminating stagnation;
Olibanum (processed with vinegar): be the resin that olive subject plant Boswellia carterii and congener skin zone thereof ooze out, Xin Xiang walks to alter, and bitter in the mouth is removed heat by catharsis into blood, the eliminating carbuncle of invigorating blood circulation, putrefaction-removing granulation-promoting;
Myrrha (processed with vinegar): be the oleo-gum-resin that olive subject plant myrrh and congener skin zone thereof ooze out, effect is similar in Olibanum, is usefulness in the Olibanum mutual reinforcement between, and Olibanum is longer than circulation of qi promoting, and Myrrha is longer than blood circulation promoting and blood stasis dispelling;
Semen Vaccariae (parched): begin to be stated from Shennong's Herbal, the dysmenorrhea of invigorating blood circulation, stimulating milk secretion eliminating carbuncle, inducing diuresis for treating stranguria syndrome;
The Pericarpium Citri Reticulatae Viride toil, hot loose temperature is logical, and bitter diarrhea is capable, the breast side of body swelling of being suitable for stagnation of QI due to depression of the liver to produce, hernia pain, breast swell and pain is the key medicine of regulating the flow of vital energy;
Artificial Moschus: Xin Wen, external can blood circulation promoting and dispersing pathogen accumulation, reducing swelling and alleviating pain, but priming is expert herein, promotes all medicine performance curative effects.
Advantage of the present invention is: it is the Chinese medicine of depressed liver-energy dispersing and QI regulating, hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, supplementing QI for promoting the production of body fluid, removing obstruction in the collateral to relieve pain that a kind of effect is provided, be used for the treatment of cyclomastopathy, the capable of regulating menoxenia promotes breast fitness simultaneously, and this Chinese medicine is easy to use, low price.
Taboo: menstrual period need not, anemia of pregnant woman, dysfunctional uterine hemorrhage and unknown cause menorrhagia person forbidding.
The specific embodiment
Embodiment 1: 20 parts of Concha Ostreae, 20 parts of Radix Salviae Miltiorrhizaes, 20 parts of Sargassums, 20 parts of the Radixs Astragali, 10 parts of Herba Taraxacis, 3 parts of Olibanum (processed with vinegar), 3 parts of Myrrha (processed with vinegar), 3 parts of Semen Vaccariae (parched)s, 3 parts on Pericarpium Citri Reticulatae Viride, 0.01 part of artificial Moschus.Preparation method is: each material medicine by weight co-grinding, is made powder, and in the bottle of packing into, every bottle 3 gram.
Embodiment 2: 10 parts of Concha Ostreae, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Sargassums, 10 parts of the Radixs Astragali, 5 parts of Herba Taraxacis, 1 part of Olibanum (processed with vinegar), 1 part of Myrrha (processed with vinegar), 1 part of Semen Vaccariae (parched), 1 part on Pericarpium Citri Reticulatae Viride, 0.005 part of artificial Moschus.Preparation method is with embodiment 1.
Embodiment 3: 30 parts of Concha Ostreae, 30 parts of Radix Salviae Miltiorrhizaes, 30 parts of Sargassums, 30 parts of the Radixs Astragali, 15 parts of Herba Taraxacis, 5 parts of Olibanum (processed with vinegar), 5 parts of Myrrha (processed with vinegar), 5 parts of Semen Vaccariae (parched)s, 5 parts on Pericarpium Citri Reticulatae Viride, 0.02 part of artificial Moschus.Preparation method is with embodiment 1.
Embodiment 4: 15 parts of Concha Ostreae, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Sargassums, 15 parts of the Radixs Astragali, 12 parts of Herba Taraxacis, 2 parts of Olibanum (processed with vinegar), 2 parts of Myrrha (processed with vinegar), 2 parts of Semen Vaccariae (parched)s, 2 parts on Pericarpium Citri Reticulatae Viride, 0.015 part of artificial Moschus.Preparation method is with embodiment 1.
Clinical experimental study of the present invention:
Above optimum formula is through clinical trial 12 examples, and the treatment cyclomastopathy is cured 2 examples (16.7%), produce effects 7 examples (58.3%), effective 2 examples (16.7%), invalid 1(8.3%) example, and the breast fitness of promotion effect is arranged, its medical expense only is equivalent to 1/3rd of oral drugs.
The clinical experimental study report
1, case choice criteria
The diagnostic criteria or the dialectical standard of traditional Chinese medical science qi depression to blood stasis disease that meet the doctor trained in Western medicine cyclomastopathy, the age, informed consent or aspiration were agreed in 18-55 year.
The Western medicine diagnose standard has following Four types:
(1) mastalgia type: can be dull pain, dull pain or distending pain, or claim " cyclomastopathy ", how before menstruation, occurred in 5-7 days, alleviate behind the menstrual onset or disappear;
(2) adenopathy type: be a kind of benign lesion that grows up on the cyclomastopathy basis, what breast can touch hard tough bar shuttle shape thickens body of gland and ridge sample lump;
(3) fibrosing type: the half patient has infertility, and minority is with menstruation fore udder distending pain, and that breast can touch is irregular, boundary is unclear, and is rough, and strong but pliable in texture swollen thing is without touching a tender spot;
(4) cystic disease type: main feature is Epithelial hyperplasia, and conduit is extremely expanded and formed the cyst that differs in size, and shows as distending pain of the breast, and is irrelevant with menstruation.
But above Four types individualism also can appear in the lobule simultaneously.
Auxiliary examination: X ray, ultrasonic examination, noctovisor scan, CT and MRI, breast duct scope, pathological examination etc.
The tcm diagnosis standard: belong to nodules of the breast, and nodule in the breast, shape such as ball ovum or the pendant that hangs down, cry the pain or not bitterly, color of the leather is constant, its nuclear increases with susceptible to anger, system is by worry impairing spleen, angry impairing the liver, and pent-up forms, simultaneously with Hypomenorrhea, color is dark or clot is arranged, abdominal pain during menstruation, dimly red tongue, tire is thin white, ecchymosis is arranged, and stringy pulse or string are puckery.
2, medicine ingredient
Concha Ostreae, Radix Salviae Miltiorrhizae, Sargassum, the Radix Astragali, Herba Taraxaci, Olibanum (processed with vinegar), Myrrha (processed with vinegar), Semen Vaccariae (parched), Pericarpium Citri Reticulatae Viride, artificial Moschus.
3, administrated method
Usage and dosage is: medicated powder is put into umbilicus, become pasty state with the vinegar moistening, use the sponge sheet gland, use immobilization with adhesive tape again, get final product.Each one bottle, according to state of an illness weight, change once every 2-3 day, 8-12 time is a course for the treatment of.
Taboo: menstrual period need not, anemia of pregnant woman, dysfunctional uterine hemorrhage and unknown cause menorrhagia person forbidding.
4, the criterion of curative effect
Cure: lump in breast, pain disappear;
Produce effects: lump in breast, pain be bright to be alleviated or disappears, and the lump in breast major diameter dwindles
Figure BDA00002445074500031
Effectively: lump in breast, pain be bright to be alleviated or disappears, and the lump in breast major diameter dwindles
Figure BDA00002445074500032
Invalid: lump in breast, pain is without change, or the lump in breast major diameter dwindle less than
Figure BDA00002445074500041
5, case treatment situation
12 cases treatment information slip
Result: cure rate 16.7%, obvious effective rate 58.3%, effective percentage 16.7%, inefficiency 8.3%.

Claims (3)

1. Chinese medicine for the treatment of cyclomastopathy, it is characterized in that the weight portion that respectively forms of this Chinese medicine is: Concha Ostreae 10-30 part, Radix Salviae Miltiorrhizae 10-30 part, Sargassum 10-30 part, Radix Astragali 10-30 part, Herba Taraxaci 5-15 part, Olibanum (processed with vinegar) 1-5 part, Myrrha (processed with vinegar) 1-5 part, Semen Vaccariae (parched) 1-5 part, Pericarpium Citri Reticulatae Viride 1-5 part and artificial Moschus 0.005-0.02 part.
2. Chinese medicine according to claim 1, it is characterized in that the optimum formula of this Chinese medicine is: 20 parts of Concha Ostreae, 20 parts of Radix Salviae Miltiorrhizaes, 20 parts of Sargassums, 20 parts of the Radixs Astragali, 10 parts of Herba Taraxacis, 3 parts of Olibanum (processed with vinegar), 3 parts of Myrrha (processed with vinegar), 3 parts of Semen Vaccariae (parched)s, 3 parts on Pericarpium Citri Reticulatae Viride, 0.01 part of artificial Moschus.
3. the preparation method of a Chinese medicine as claimed in claim 1 is characterized in that, preparation method is: various material medicines by weight co-grinding, are made powder, and bottling gets final product.
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104645233A (en) * 2015-02-11 2015-05-27 张朋 Traditional Chinese medicine preparation for treating hyperplasia of mammary glands
CN104840904A (en) * 2015-06-12 2015-08-19 李兰珍 Traditional Chinese medicine composition for treating hyperplasia of mammary glands
CN108030884A (en) * 2017-12-26 2018-05-15 支誉英 A kind of Chinese medicine for treating mastosis and preparation method thereof
CN109172728A (en) * 2018-10-31 2019-01-11 田春生 A kind of drug for treating the proliferation of mammary gland

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104645233A (en) * 2015-02-11 2015-05-27 张朋 Traditional Chinese medicine preparation for treating hyperplasia of mammary glands
CN104840904A (en) * 2015-06-12 2015-08-19 李兰珍 Traditional Chinese medicine composition for treating hyperplasia of mammary glands
CN108030884A (en) * 2017-12-26 2018-05-15 支誉英 A kind of Chinese medicine for treating mastosis and preparation method thereof
CN109172728A (en) * 2018-10-31 2019-01-11 田春生 A kind of drug for treating the proliferation of mammary gland

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