CN102451429A - Method for preparing Ruan Pian - Google Patents
Method for preparing Ruan Pian Download PDFInfo
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- CN102451429A CN102451429A CN2010105164936A CN201010516493A CN102451429A CN 102451429 A CN102451429 A CN 102451429A CN 2010105164936 A CN2010105164936 A CN 2010105164936A CN 201010516493 A CN201010516493 A CN 201010516493A CN 102451429 A CN102451429 A CN 102451429A
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Abstract
The invention relates to a method for preparing Ruan Pian, which comprises the following steps: 1) choosing trigone, malt, atractylis ovata, bupleurum, rhizome zedoariae, chickens gizzardskin and green tangerine orange peel, then sterilizing in a disinfection cabinet, mixing with myrrh and mastic, and then crushing into powder to obtain raw powder; 2) extracting and concentrating: weighting salvia miltiorrhiza, epimedium , cochinchinese asparagus root, alga, oyster and astragalus root, adding drinking water by tree times with 8 times, 6 times and 6 times of weight of medicinal material, and boiling and extracting for three times, wherein the decoction time are two hours, one and a half hour, and one hour respectively, extracting the concentration fluid to a extract with relative density of 1.22-1.24. 3) placing raw powder and auxiliary materials into a container of a boiling drying granulator, and spraying the extract under the boiling state, heating by hot air in the granulator, removing the moisture in the extract. adhering the extract and raw powder to prepare the particles; 4) pressing the obtained particles in a tablet press to obtain the tablet, coating a layer of grass green membrane by a film coating method, packaging if the quality is qualified. Using the Ruan Pian produced by the invention to cure hyperplasia of mammary glands can be free from operation, and can treat the disease completely with high treatment rate and low relapse rate, and has good social value.
Description
Technical field
The present invention relates to a kind of method for preparing of medicine, especially relates to a kind of method for preparing of breast peace sheet.
Background technology
Chinese medicinal tablet is the Formulation that means that medicinal substances extract, medicinal substances extract add that medical material or medical material fine powder and proper auxiliary materials mixing are neutralized or process with other proper method.Chinese medicinal tablet is Chinese medicine traditional theory and the product that modern pharmaceutical, theory, equipment combine, and has characteristics such as production is easy, taking convenience.Breast peace sheet is a kind of regulating the flow of QI to dissipate blood stasis that has, and the effect medicine of hard masses softening and resolving clinically is used for the nodules of the breast person that belongs to the syndrome of qi stagnation and blood stasis.
Summary of the invention
The purpose of this invention is to provide a kind of method for preparing breast peace sheet, this breast peace sheet has regulating the flow of QI to dissipate blood stasis, the effect of hard masses softening and resolving.
To achieve these goals; Technical scheme of the present invention has adopted a kind of method for preparing breast peace sheet; May further comprise the steps: triangular, Fructus Hordei Germinatus, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Curcumae, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae Viride are got in (1), prior to sterilizing in the sterilization cabinet, are broken into fine powder with Myrrha, Olibanum mixed powder; Mix homogeneously promptly gets fecula; (2) extraction concentrates: get Radix Salviae Miltiorrhizae, Herba Epimedii, Radix Asparagi, Sargassum, Concha Ostreae, Radix Astragali Six-element medical material; Divide the drinking water that adds 8,6,6 times of amounts of medical material weight for three times; Decoct and extract three times; Frying in shallow oil the time of carrying for three times is respectively 2h, 1.5h, 1h, and extracting solution is concentrated into relative density 1.22～1.24 extractum; (3) fecula and adjuvant are put into the container of airpillow-dry granulator, under fluidized state, sprayed into extractum,, remove the moisture in the extractum, and make extractum agglomerating, process granule with the fecula adhesion through hot blast heating in the machine; (4) the gained granule is pressed into tablet in tablet machine, and with film coating method bag one deck grass green clothing film, quality inspection is qualified, packing promptly gets.
Described each raw materials in part by weight is: 4-8 parts of Concha Ostreaes, 12-18 parts of the Radixs Astragali, triangular 1.0-1.5 parts, 0.5-1.5 parts in Fructus Hordei Germinatus, 4-8 parts of Radix Asparagis, 2.0-3.0 parts of Myrrhas, 4-8 parts of Herba Epimedii, 4-8 parts of Radix Salviae Miltiorrhizaes, 1.0-1.5 parts of the Rhizoma Atractylodis Macrocephalaes, 4-8 parts of Sargassums, 1.0-1.5 parts of Radix Bupleuri, 1.0-1.5 parts of Olibanums, 1.0-1.5 parts of Rhizoma Curcumae, 1-3 parts of Endothelium Corneum Gigeriae Galli, 1.0-1.5 parts on Pericarpium Citri Reticulatae Viride, adjuvant is 2.2-3.0 part.
Described adjuvant is the mixture of carboxymethyl starch sodium, hydroxypropyl cellulose, lactose, magnesium stearate.
Wherein carboxymethyl starch sodium is 0.1-0.3 part, hydroxypropyl cellulose 0.5-0.7 part, lactose 1.5-1.7 part, magnesium stearate 0.1-0.3 part.
The used raw material of method of the present invention is Radix Salviae Miltiorrhizae, the Rhizoma Curcumae that adopts blood circulation promoting and blood stasis dispelling, the Pericarpium Citri Reticulatae Viride of the eliminating stagnation of regulating the flow of vital energy, Radix Bupleuri, and Chinese medicines such as the Herba Epimedii of Chong and Ren Meridians regulating, each raw material share has regulating the flow of QI to dissipate blood stasis, the effect of hard masses softening and resolving.Do not perform the operation when adopting the breast peace sheet treatment cyclomastopathy of method of the present invention preparation, do not operate on, treating both the principal and secondary aspects of a disease, cure rate are high, it is low to cure the back relapse rate, have favorable social.
Description of drawings
Fig. 1 is a process chart of the present invention.
The specific embodiment
Embodiment 1
As shown in Figure 1; The present invention prepares the method for breast peace sheet; May further comprise the steps: triangular 1.0 weight portions, Fructus Hordei Germinatus 0.5 weight portion, the Rhizoma Atractylodis Macrocephalae 1.0 weight portions, Radix Bupleuri 1.0 weight portions, Rhizoma Curcumae 1.0 weight portions, Endothelium Corneum Gigeriae Galli 1 weight portion, Pericarpium Citri Reticulatae Viride 1 weight portion are got in (1), prior to sterilizing in the sterilization cabinet, are broken into fine powder with the Myrrha of 2 weight portions, the Olibanum mixed powder of 1 weight portion; Mix homogeneously promptly gets fecula; (2) extraction concentrates: get Radix Salviae Miltiorrhizae 4 weight portions, Herba Epimedii 4 weight portions, Radix Asparagi 4 weight portions, Sargassum 4 weight portions, Concha Ostreae 5 weight portions, the Radix Astragali 12 weight portion Six-element medical materials; Divide the drinking water that adds 8,6,6 times of amounts of medical material weight for three times; Decoct and extract three times; Frying in shallow oil the time of carrying for three times is respectively 2h, 1.5h, 1h, and extracting solution is concentrated into the extractum of relative density 1.22; (3) fecula and adjuvant are put into the container of airpillow-dry granulator, under fluidized state, sprayed into extractum,, remove the moisture in the extractum, and make extractum agglomerating, process granule with the fecula adhesion through hot blast heating in the machine; (4) the gained granule is pressed into tablet in tablet machine, and with film coating method bag one deck grass green clothing film, quality inspection is qualified, packing promptly gets.
Wherein, consisting of of adjuvant: carboxymethyl starch sodium is 0.1 part, 0.5 part of hydroxypropyl cellulose, 1.5 parts of lactose, 0.1 part of magnesium stearate.
Embodiment 2
The present invention prepares the method for breast peace sheet; May further comprise the steps: triangular 1.2 weight portions, Fructus Hordei Germinatus 1.0 weight portions, the Rhizoma Atractylodis Macrocephalae 1.2 weight portions, Radix Bupleuri 1.2 weight portions, Rhizoma Curcumae 1.2 weight portions, Endothelium Corneum Gigeriae Galli 1.5 weight portions, Pericarpium Citri Reticulatae Viride 1.2 weight portions are got in (1); Prior to sterilizing in the sterilization cabinet; Be broken into fine powder with the Myrrha of 2.5 weight portions, the Olibanum mixed powder of 1.2 weight portions, mix homogeneously promptly gets fecula; (2) extraction concentrates: get Radix Salviae Miltiorrhizae 6 weight portions, Herba Epimedii 6 weight portions, Radix Asparagi 6 weight portions, Sargassum 6 weight portions, Concha Ostreae 6 weight portions, the Radix Astragali 15 weight portion Six-element medical materials; Divide the drinking water that adds 8,6,6 times of amounts of medical material weight for three times; Decoct and extract three times; Frying in shallow oil the time of carrying for three times is respectively 2h, 1.5h, 1h, and extracting solution is concentrated into the extractum of relative density 1.23; (3) fecula and adjuvant are put into the container of airpillow-dry granulator, under fluidized state, sprayed into extractum,, remove the moisture in the extractum, and make extractum agglomerating, process granule with the fecula adhesion through hot blast heating in the machine; (4) the gained granule is pressed into tablet in tablet machine, and with film coating method bag one deck grass green clothing film, quality inspection is qualified, packing promptly gets.
Wherein, consisting of of adjuvant: carboxymethyl starch sodium is 0.2 part, 0.6 part of hydroxypropyl cellulose, 1.6 parts of lactose, 0.2 part of magnesium stearate.
Embodiment 3
The present invention prepares the method for breast peace sheet; May further comprise the steps: triangular 1.5 weight portions, Fructus Hordei Germinatus 1.5 weight portions, the Rhizoma Atractylodis Macrocephalae 1.5 weight portions, Radix Bupleuri 1.5 weight portions, Rhizoma Curcumae 1.5 weight portions, Endothelium Corneum Gigeriae Galli 3 weight portions, Pericarpium Citri Reticulatae Viride 1.5 weight portions are got in (1); Prior to sterilizing in the sterilization cabinet; Be broken into fine powder with the Myrrha of 4 weight portions, the Olibanum mixed powder of 1.5 weight portions, mix homogeneously promptly gets fecula; (2) extraction concentrates: get Radix Salviae Miltiorrhizae 8 weight portions, Herba Epimedii 8 weight portions, Radix Asparagi 8 weight portions, Sargassum 8 weight portions, Concha Ostreae 8 weight portions, the Radix Astragali 18 weight portion Six-element medical materials; Divide the drinking water that adds 8,6,6 times of amounts of medical material weight for three times; Decoct and extract three times; Frying in shallow oil the time of carrying for three times is respectively 2h, 1.5h, 1h, and extracting solution is concentrated into the extractum of relative density 1.24; (3) fecula and adjuvant are put into the container of airpillow-dry granulator, under fluidized state, sprayed into extractum,, remove the moisture in the extractum, and make extractum agglomerating, process granule with the fecula adhesion through hot blast heating in the machine; (4) the gained granule is pressed into tablet in tablet machine, and with film coating method bag one deck grass green clothing film, quality inspection is qualified, packing promptly gets.
Wherein, consisting of of adjuvant: carboxymethyl starch sodium is 0.3 part, 0.7 part of hydroxypropyl cellulose, 1.7 parts of lactose, 0.3 part of magnesium stearate.
Claims (4)
1. the method for preparing of a breast peace sheet; It is characterized in that: may further comprise the steps: triangular, Fructus Hordei Germinatus, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Curcumae, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae Viride are got in (1), prior to sterilizing in the sterilization cabinet, are broken into fine powder with Myrrha, Olibanum mixed powder; Mix homogeneously promptly gets fecula; (2) extraction concentrates: get Radix Salviae Miltiorrhizae, Herba Epimedii, Radix Asparagi, Sargassum, Concha Ostreae, Radix Astragali Six-element medical material; Divide the drinking water that adds 8,6,6 times of amounts of medical material weight for three times; Decoct and extract three times; Frying in shallow oil the time of carrying for three times is respectively 2h, 1.5h, 1h, and extracting solution is concentrated into relative density 1.22～1.24 extractum; (3) fecula and adjuvant are put into the container of airpillow-dry granulator, under fluidized state, sprayed into extractum,, remove the moisture in the extractum, and make extractum agglomerating, process granule with the fecula adhesion through hot blast heating in the machine; (4) the gained granule is pressed into tablet in tablet machine, and with film coating method bag one deck grass green clothing film, quality inspection is qualified, packing promptly gets.
2. the method for preparing of breast peace sheet according to claim 1; It is characterized in that: described each raw materials in part by weight is: 4-8 parts of Concha Ostreaes, 12-18 parts of the Radixs Astragali, triangular 1.0-1.5 parts, 0.5-1.5 parts in Fructus Hordei Germinatus, 4-8 parts of Radix Asparagis, 2.0-3.0 parts of Myrrhas, 4-8 parts of Herba Epimedii, 4-8 parts of Radix Salviae Miltiorrhizaes, 1.0-1.5 parts of the Rhizoma Atractylodis Macrocephalaes, 4-8 parts of Sargassums, 1.0-1.5 parts of Radix Bupleuri, 1.0-1.5 parts of Olibanums, 1.0-1.5 parts of Rhizoma Curcumae, 1-3 parts of Endothelium Corneum Gigeriae Galli, 1.0-1.5 parts on Pericarpium Citri Reticulatae Viride, adjuvant is 2.2-3.0 part.
3. the method for preparing of breast peace sheet according to claim 1, it is characterized in that: described adjuvant is the mixture of carboxymethyl starch sodium, hydroxypropyl cellulose, lactose, magnesium stearate.
4. the method for preparing of breast peace sheet according to claim 3, it is characterized in that: carboxymethyl starch sodium is 0.1-0.3 part, hydroxypropyl cellulose 0.5-0.7 part, lactose 1.5-1.7 part, magnesium stearate 0.1-0.3 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105164936A CN102451429A (en) | 2010-10-23 | 2010-10-23 | Method for preparing Ruan Pian |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105164936A CN102451429A (en) | 2010-10-23 | 2010-10-23 | Method for preparing Ruan Pian |
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| Publication Number | Publication Date |
|---|---|
| CN102451429A true CN102451429A (en) | 2012-05-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105164936A Pending CN102451429A (en) | 2010-10-23 | 2010-10-23 | Method for preparing Ruan Pian |
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| CN (1) | CN102451429A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102988543A (en) * | 2012-11-21 | 2013-03-27 | 郑州瑞龙制药股份有限公司 | Traditional Chinese medicine for treating hyperplasia of mammary glands and preparation method of traditional Chinese medicine |
| CN104706718A (en) * | 2015-04-01 | 2015-06-17 | 四川宇妥藏药股份有限公司 | Three-ingredient Chinese gentian flower tablets and preparation method thereof |
-
2010
- 2010-10-23 CN CN2010105164936A patent/CN102451429A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 国家药品监督管理局: "《国家药品监督管理局，国家中成药标准汇编，中成药地方标准上升国家标准部分，外科 妇科分册》", 31 December 2002 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102988543A (en) * | 2012-11-21 | 2013-03-27 | 郑州瑞龙制药股份有限公司 | Traditional Chinese medicine for treating hyperplasia of mammary glands and preparation method of traditional Chinese medicine |
| CN104706718A (en) * | 2015-04-01 | 2015-06-17 | 四川宇妥藏药股份有限公司 | Three-ingredient Chinese gentian flower tablets and preparation method thereof |
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Application publication date: 20120516 |