CN102357193A

CN102357193A - Traditional Chinese medicament for curing mammary hyperplasia

Info

Publication number: CN102357193A
Application number: CN2011103374436A
Authority: CN
Inventors: 宋丽峰
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-10-16
Filing date: 2011-10-16
Publication date: 2012-02-22

Abstract

The invention discloses a traditional Chinese medicament for curing mammary hyperplasia. According to the causes of formation of the mammary hyperplasia, namely, stagnation of the circulation of vital energy, blood stasis and phlegm coagulation, the medicament selects the Chinese medicinal herbs of radix bupleuri, angelica sinensis, spina date seeds, radix paeoniae alba, seaweeds, moutan barks, radices lithospermi, roots of red-rooted salvia, saffron, root barks of tree peony, antlers, raw rhizoma arisaematis, endothelium corneum gigeriae galli, hawthorns, scorpio, radix ophiopogonis and schisandra chinensis which have the functions of soothing the liver, regulating vital energy, invigorating the circulation of blood, removing blood stasis, dissolving phlegm and dissipating binds to prepare decoction for dosage. According to clinical tests, the total effective rate reaches 97.5%, and further, the medicament has no side effect and is low in curing cost and worthy of clinical popularization and application.

Description

A kind of Chinese medicine preparation of treating cyclomastopathy

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation of treating cyclomastopathy.

Background technology

Cyclomastopathy is common clinically a kind of mastopathy; Its essence is that mammary structure is disorderly; Showing as mammary gland fibrous tissue and epithelial proliferation companion cyst forms; Clinical characters is that lump and distending pain appear in mammary gland, changes with menstrual cycle, and clinical symptoms weight person has a strong impact on patient's quality of worklife and perplexing whole family.And the reason that causes cyclomastopathy is a lot, like endocrine disturbance, Nervous and Mental Factors, trophic factor, life style etc.Its sickness rate occupies first of the cystic hyperplasia of breast, is common gynecological disease, frequently-occurring disease, is cardinal symptom with distending pain of the breast and lump, gives patient's spirit and animally all brings very big misery.

The medicine of treatment cyclomastopathy has Western medicine and Chinese medicine.Western medicine tamoxifen and derivatives for treatment cyclomastopathy thereof have obtained clinical confirmation, but it also has some significant side effects simultaneously.The treatment by Chinese herbs cyclomastopathy is safer, but curative effect differs greatly.

Summary of the invention

The purpose of this invention is to provide a kind of Chinese medicine preparation of treating cyclomastopathy, the cause of disease that said preparation forms to cyclomastopathy, promptly the stagnation of QI, blood stasis, expectorant coagulate, and the Chinese herbal medicine of selecting to have depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, vanishing sputum and dispelling knot is processed decoction.

The objective of the invention is to realize through following technical scheme; The Chinese medicine preparation of this treatment cyclomastopathy is processed by following parts by weight of Chinese traditional medicine: Radix Bupleuri 7-11 part, Radix Angelicae Sinensis 9-15 part, Semen Ziziphi Spinosae 6-9 part, Radix Paeoniae Alba 6-9 part, Sargassum 5-7 part, Cortex Moutan 7-11 part, Radix Arnebiae (Radix Lithospermi) 5-7 part, Radix Salviae Miltiorrhizae 7-11 part, Stigma Croci 6-9 part, Cortex Moutan 5-7 part, Cornu Cervi 6-9 part, Rhizoma Arisaematis 7-11 part, Endothelium Corneum Gigeriae Galli 5-7 part, Fructus Crataegi 6-9 part, Scorpio 5-7 part, Radix Ophiopogonis 5-7 part, Fructus Schisandrae Chinensis 5-7 part.

Preferably; The Chinese medicine preparation of this treatment cyclomastopathy is processed by following parts by weight of Chinese traditional medicine: 9 parts of Radix Bupleuri, 12 parts of Radix Angelicae Sinensis, 7 parts of Semen Ziziphi Spinosaes, 7 parts of the Radix Paeoniae Albas, 6 parts of Sargassums, 9 parts of Cortex Moutans, 6 parts of Radix Arnebiae (Radix Lithospermi)s, 9 parts of Radix Salviae Miltiorrhizaes, 7 parts of Stigma Crocis, 6 parts of Cortex Moutans, 7 parts on Cornu Cervi, 9 parts of Rhizoma Arisaematis, 6 parts of Endothelium Corneum Gigeriae Galli, 7 parts of Fructus Crataegis, 6 parts of Scorpios, 6 parts of Radix Ophiopogonis, 6 parts of Fructus Schisandrae Chinensis.

Take by the fried one-tenth decoction of conventional method.

Radix Bupleuri, Radix Angelicae Sinensis, Semen Ziziphi Spinosae, the Radix Paeoniae Alba, Sargassum, Fructus Crataegi depressed liver-energy dispersing and QI regulating, resolving phlegm and softening hard masses in the side; Cortex Moutan, Radix Arnebiae (Radix Lithospermi), Radix Salviae Miltiorrhizae, Stigma Croci, Cortex Moutan, Cornu Cervi blood circulation promoting and blood stasis dispelling; Rhizoma Arisaematis, Endothelium Corneum Gigeriae Galli, Scorpio vanishing sputum and dispelling knot, removing obstruction in the collateral to relieve pain; Add Radix Ophiopogonis, Fructus Schisandrae Chinensis YIN nourishing and the production of body fluid promoting; Hard masses softening and resolving plays, the eliminating carbuncle of invigorating blood circulation, the function of heat-clearing and toxic substances removing altogether in full side compatibility each other.

Clinical data

1, clinical data

My gate in 2007 to 2009 is examined 160 examples of accepting for medical treatment be diagnosed as the object of study of the female patients of cyclomastopathy as this test.Be divided into treatment group and matched group at random, every group 80 example, the treatment group, the age minimum is 20 years old, is 58 years old to the maximum, and the mean age is 34.5 years old, and the course of disease 3 months did not wait average 12 months to 10 years; Matched group: the age minimum is 21 years old, is 59 years old to the maximum, and the mean age is 35 years old, the course of disease 3 months to 10 years, average 12.5 months.Among two groups of patients, wherein 69 examples were once accepted treatment by Chinese herbs, DeGrain, and 72 examples were once used tamoxifen treatment, but stopped using greatly because of side effect.

2, inclusion criteria

Diagnostic criteria with reference to the 2nd the breast disease academic conference formulation of national surgery of Chinese medicine association: symptom and sign: breast has distending pain, twinge in various degree; Can be radiated to oxter, shoulder back; Can dependency be arranged with menstruation, emotion changes, continuous 3 months or be interrupted and alleviated in pain 3-6 month; The lump that the one or both sides breast takes place single or a plurality ofly to differ in size, form is various; Lump can be scattered in The entire breast, and is unclear with the surrounding tissue boundary, with skin or deep tissue adhesion; Push away movable; Tenderness can be arranged, can growth and decline with the variation of emotion and menstrual cycle, part patient can have discharge or pruritus.

3, Therapeutic Method

The treatment group is taken Chinese medicine decoction of the present invention, fries in shallow oil two doses every day 1; Matched group: oral tamoxifen 10mg, two groups of homogeneous Zhou Weiyi courses of treatment, serve on three courses of treatment at every day 2 times.

4, criterion of therapeutical effect

1. produce effects: distending pain of the breast disappears, and mammary gland is tough firmly, thickened areas disappear or significantly dwindle, matter is soft.2. alleviate: distending pain of the breast obviously alleviates, and mammary gland is tough firmly, thickened areas is dwindled.3. invalid: symptom and sign all do not have obvious improvement after three course of therapy.

5, therapeutic outcome

After treating three courses of treatment, the statistics therapeutic outcome: treatment is organized among the 80 routine patients, produce effects 51 examples, and obvious effective rate 63.8% is alleviated 27 examples, invalid 2 examples, total effective rate 97.5%; Among the matched group 80 routine patients, produce effects 33 examples, obvious effective rate 41.3% is alleviated 22 examples, invalid 25 examples, total effective rate is 68.8%.

The treatment group all patients have no adverse reaction; There are 16 routine patients untoward reaction to occur in the matched group.

The specific embodiment

Embodiment one: get Radix Bupleuri 9g, Radix Angelicae Sinensis 12g, Semen Ziziphi Spinosae 7g, Radix Paeoniae Alba 7g, Sargassum 6g, Cortex Moutan 9g, Radix Arnebiae (Radix Lithospermi) 6g, Radix Salviae Miltiorrhizae 9g, Stigma Croci 7g, Cortex Moutan 6g, Cornu Cervi 7g, Rhizoma Arisaematis 9g, Endothelium Corneum Gigeriae Galli 6g, Fructus Crataegi 7g, Scorpio 6g, Radix Ophiopogonis 6g, Fructus Schisandrae Chinensis 6g.Fried by conventional decocting method, fry in shallow oil twice and take every day 1.

Embodiment two: get Radix Bupleuri 11g, Radix Angelicae Sinensis 9g, Semen Ziziphi Spinosae 9g, Radix Paeoniae Alba 6g, Sargassum 5g, Cortex Moutan 11g, Radix Arnebiae (Radix Lithospermi) 7g, Radix Salviae Miltiorrhizae 7g, Stigma Croci 9g, Cortex Moutan 7g, Cornu Cervi 9g, Rhizoma Arisaematis 7g, Endothelium Corneum Gigeriae Galli 7g, Fructus Crataegi 9g, Scorpio 5g, Radix Ophiopogonis 7g, Fructus Schisandrae Chinensis 5g.Fried by conventional decocting method, fry in shallow oil twice and take every day 1.

Embodiment three: get Radix Bupleuri 7g, Radix Angelicae Sinensis 15g, Semen Ziziphi Spinosae 6g, Radix Paeoniae Alba 9g, Sargassum 7g, Cortex Moutan 7g, Radix Arnebiae (Radix Lithospermi) 5g, Radix Salviae Miltiorrhizae 11g, Stigma Croci 6g, Cortex Moutan 5g, Cornu Cervi 6g, Rhizoma Arisaematis 11g, Endothelium Corneum Gigeriae Galli 5g, Fructus Crataegi 6g, Scorpio 7g, Radix Ophiopogonis 5g, Fructus Schisandrae Chinensis 7g.Fried by conventional decocting method, fry in shallow oil twice and take every day 1.

Claims

1. Chinese medicine preparation of treating cyclomastopathy; It is characterized in that processing by following parts by weight of Chinese traditional medicine: Radix Bupleuri 7-11 part, Radix Angelicae Sinensis 9-15 part, Semen Ziziphi Spinosae 6-9 part, Radix Paeoniae Alba 6-9 part, Sargassum 5-7 part, Cortex Moutan 7-11 part, Radix Arnebiae (Radix Lithospermi) 5-7 part, Radix Salviae Miltiorrhizae 7-11 part, Stigma Croci 6-9 part, Cortex Moutan 5-7 part, Cornu Cervi 6-9 part, Rhizoma Arisaematis 7-11 part, Endothelium Corneum Gigeriae Galli 5-7 part, Fructus Crataegi 6-9 part, Scorpio 5-7 part, Radix Ophiopogonis 5-7 part, Fructus Schisandrae Chinensis 5-7 part.

2. a kind of Chinese medicine preparation of treating cyclomastopathy according to claim 1; It is characterized in that processing: 9 parts of Radix Bupleuri, 12 parts of Radix Angelicae Sinensis, 7 parts of Semen Ziziphi Spinosaes, 7 parts of the Radix Paeoniae Albas, 6 parts of Sargassums, 9 parts of Cortex Moutans, 6 parts of Radix Arnebiae (Radix Lithospermi)s, 9 parts of Radix Salviae Miltiorrhizaes, 7 parts of Stigma Crocis, 6 parts of Cortex Moutans, 7 parts on Cornu Cervi, 9 parts of Rhizoma Arisaematis, 6 parts of Endothelium Corneum Gigeriae Galli, 7 parts of Fructus Crataegis, 6 parts of Scorpios, 6 parts of Radix Ophiopogonis, 6 parts of Fructus Schisandrae Chinensis by following parts by weight of Chinese traditional medicine.