CN102247581A - Medicament for treating myoma of uterus - Google Patents

Abstract

The invention discloses a medicament for treating myoma of uterus. The medicament is prepared by the following steps of: uniformly mixing vinegar-baked bupleurum root, vinegar-baked nutgrass galingale rhizome, angelica, szechuan lovage rhizome, peach kernel, common burreed rhizome, zedoary, root of red-rooted salvia, red paeony root, scrophularia, selfheal spike, root bark of the peony tree, leech, bulbus fritillariae thunbergii and licorice root which are selected and cleaned by using clear water; crushing the raw materials into 100-mesh to 120-mesh medicinal powder; and preparing a watered pill product by taking pure water as an adhesive according to the conventional method. The medicament has the effects of soothing the liver and regulating vital energy, promoting blood circulation to remove blood stasis, eliminating stagnation and removing swelling; and the aims of quick response to treatment of the myoma of uterus, low side effect and low cost are fulfilled.

Description

A kind of medicine for the treatment of hysteromyoma

Technical field

The present invention relates to a kind of medicine for the treatment of hysteromyoma, particularly relating to a kind of is the medicine of the treatment hysteromyoma of crude drug preparation with Chinese medicine.

Background technology

Hysteromyoma (Hysteromyoma) claim leiomyoma of uterus again, is the modal a kind of benign tumors of female sex organs.How asymptomatic, minority shows as vaginal hemorrhage, and abdominal part touches swollen thing and pressure symptom etc.As can cause pain when torsion of pedicle or other situations take place, common with multiple myomata.

Hysteromyoma is very big to women's harm, may cause situations such as infertile, suppurative inflammation, canceration as untimely treatment, has had a strong impact on the healthy of women.

The treatment primary disease mainly passes through methods such as operative treatment, Drug therapy at present, but these methods cost an arm and a leg, patient is painful big.

Summary of the invention

The purpose of this invention is to provide a kind of medicine for the treatment of hysteromyoma, this medicine is made up of Chinese medicine, has the effect of depressed liver-energy dispersing and QI regulating, activating blood circulation to dissipate blood stasis, mass dissipating and swelling eliminating, can play instant effect, side effect is little, expense is low purpose to the treatment of hysteromyoma.

Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Radix Bupleuri (processed with vinegar) 8～12 Rhizoma Cyperi (processed with vinegar) 8～12 Radix Angelicae Sinensis 8～12

Rhizoma Chuanxiong 8～12 Semen Persicaes 8～12 rhizoma sparganic 12～18

Rhizoma Curcumae 12～18 Radix Salviae Miltiorrhizaes 24～36 Radix Paeoniae Rubra 12～18

Radix Scrophulariae 12～18 Spica Prunellaes 12～18 Cortex Moutans 12～18

Hirudo 3～5 Bulbus Fritillariae Thunbergii 12～18 Radix Glycyrrhizaes 4～8.

Said medicine can be made any dosage form on the pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is a watered pill.

The concrete preparation method of medicine of the present invention being made watered pill is:

Said medicine is cleaned mix homogeneously by described parts by weight, be ground into 100～120 medicated powder, make binding agent, make the watered pill product according to a conventional method with pure water.

The traditional Chinese medical science thinks that hysteromyoma mainly is because of feelings will internal injury, visceral dysfunction, and qi stagnation blood stasis forms.The Therapeutic Principle should be depressed liver-energy dispersing and QI regulating, activating blood circulation to dissipate blood stasis, mass dissipating and swelling eliminating.The Radix Bupleuri (processed with vinegar) dispersing the stagnated live-QI to relieve the stagnation of QI, regulate the flow of vital energy and blood; Rhizoma Cyperi (processed with vinegar) depressed liver-energy dispersing and QI regulating, eliminating stagnation repercussive; Chinese angelica blood supplementing is invigorated blood circulation, the blood stasis dispelling regulating menstruation; Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression; Semen Persicae blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating; Rhizoma sparganic removing blood stasis, circulation of qi promoting removing food stagnancy; Rhizoma Curcumae removing blood stasis, circulation of qi promoting removing food stagnancy; Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle; Capable stagnant, the promoting blood circulation to restore menstrual flow of Radix Paeoniae Rubra blood stasis dispelling; Radix Scrophulariae heat-clearing and toxic substances removing, eliminating stagnation eliminating carbuncle; Spica Prunellae clearing away liver-fire, Disperse hepatic depression; Cortex Moutan clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; The Hirudo removing blood stasis; Bulbus Fritillariae Thunbergii clearing heat for detumescence, dissipating phlegm and resolving masses; Radix Glycyrrhizae invigorating the spleen and replenishing QI, the mitigation property of medicine.All medicines share, and can play the effect of depressed liver-energy dispersing and QI regulating, activating blood circulation to dissipate blood stasis, mass dissipating and swelling eliminating.The treatment that is used for the treatment of hysteromyoma can be played instant effect, side effect is little, expense is low purpose.

For further investigating the clinical efficacy and the safety of medicine of the present invention, select 32 routine patients with uterine myoma that the curative effect of medicine of the present invention has been carried out clinical observation.

32 routine cases are divided into two groups at random, and 15 examples are organized in treatment, matched group 17 examples.All case is diagnosed as hysteromyoma all according to the diagnostic criteria of " new Chinese medicine clinical research guideline (first volume) ".

Diagnostic criteria

Hysteromyoma is divided into three types:

1), intramural myoma: grow in the Uterus wall Musclar layer, be this type of when just falling ill, often influence the contractility in uterus, cause through blood volume and increase, menostaxis is clinically seen at most;

2), Subserous myoma: give prominence to the surface, uterus, directly contact the eumenorrhea with serous coat;

3), fleshy polyp: to the intrauterine growth, directly contact, may grow from cavity of uterus sometimes and reach intravaginal, often form band base of a fruit muscular tumor, the easiest causing bleeding with mucous layer;

Can make a definite diagnosis according to gynecological's pelvioscopy and B ultrasonic, CT examination.

Therapeutic Method

Matched group adopts the danazol capsule, and is oral, one time 1,2 times on the one.The treatment group adopts watered pill medicine of the present invention to treat, every day 3 times, each 10 grams.30 days is a course of treatment, uses 2 courses of treatment altogether.

Criterion of therapeutical effect

According to the criterion of therapeutical effect of " new Chinese medicine clinical research guideline (first volume) ", recovery from illness: muscular tumor disappears, clinical symptom disappearance.Effectively: 1/3 above person is dwindled in sx or disappearance, muscular tumor; Or muscular tumor is stable after the drug withdrawal, and transference cure continues above person half a year; Invalid: symptom does not have change, muscular tumor and does not see obviously and dwindle.

Two groups of case treatment back curative effect comparative results see Table 1.

Table 1 liang group case treatment back curative effect relatively

Group	The example number	Recovery from illness n(%)	Effective n(%)	Invalid n(%)	Total effective rate n(%)
						Matched group	17	3（17.6）	8（47.1）	6（35.3）	11（64.7）
The treatment group	15	4（26.7）	8（53.3）	3（20）	12（80）

Statistical result showed, treatment group curative effect obviously is better than matched group, and two group differences are remarkable, P＜0.05.

The specific embodiment

Embodiment 1

Get Radix Bupleuri (processed with vinegar) 80g, Rhizoma Cyperi (processed with vinegar) 80g, Radix Angelicae Sinensis 80g, Rhizoma Chuanxiong 80g, Semen Persicae 80g, rhizoma sparganic 120g, Rhizoma Curcumae 120g, Radix Salviae Miltiorrhizae 240g, Radix Paeoniae Rubra 120g, Radix Scrophulariae 120g, Spica Prunellae 120g, Cortex Moutan 120g, Hirudo 30g, Bulbus Fritillariae Thunbergii 120g, Radix Glycyrrhizae 40g mix homogeneously selected, that clear water is cleaned, be ground into 100～120 medicated powder, make binding agent with pure water, make the watered pill according to a conventional method and produce the agent product.

Embodiment 2

Get Radix Bupleuri (processed with vinegar) 120g, Rhizoma Cyperi (processed with vinegar) 120g, Radix Angelicae Sinensis 120g, Rhizoma Chuanxiong 120g, Semen Persicae 120g, rhizoma sparganic 180g, Rhizoma Curcumae 180g, Radix Salviae Miltiorrhizae 360g, Radix Paeoniae Rubra 180g, Radix Scrophulariae 180g, Spica Prunellae 180g, Cortex Moutan 180g, Hirudo 50g, Bulbus Fritillariae Thunbergii 180g, Radix Glycyrrhizae 80g mix homogeneously selected, that clear water is cleaned, be ground into 100～120 medicated powder, make binding agent with pure water, make the watered pill product according to a conventional method.

Claims (2)

1. medicine for the treatment of hysteromyoma is that crude drug prepares by the Chinese medicine of following portions by weight:

Radix Bupleuri (processed with vinegar) 8～12 Rhizoma Cyperi (processed with vinegar) 8～12 Radix Angelicae Sinensis 8～12

Rhizoma Chuanxiong 8～12 Semen Persicaes 8～12 rhizoma sparganic 12～18

Rhizoma Curcumae 12～18 Radix Salviae Miltiorrhizaes 24～36 Radix Paeoniae Rubra 12～18

Radix Scrophulariae 12～18 Spica Prunellaes 12～18 Cortex Moutans 12～18

Hirudo 3～5 Bulbus Fritillariae Thunbergiis 12～18 Radix Glycyrrhizaes 4～8.

2. the medicine of treatment hysteromyoma according to claim 1 is characterized in that described medicine is made watered pill.