CN101912585A - Medicament for treating myoma of uterus and preparation method thereof - Google Patents
Medicament for treating myoma of uterus and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicament for treating myoma of uterus, which is characterized by being prepared from the following raw materials in part by weight: 1 to 20 parts of rose, 1 to 20 parts of seville orange flower, 1 to 20 parts of Chinese angelica, 1 to 20 parts of red paeony root, 1 to 20 parts of szechuan lovage rhizome, 1 to 20 parts of red tangerine peel, 1 to 20 parts of rhizome pinelliae preparata, 1 to 20 parts of honey-fried liquorice root, 1 to 20 parts of pared nutgrass galingale rhizome, 1 to 20 parts of scrophularia root, 1 to 20 parts of thunberg fritillary bulb, 1 to 20 parts of dipsacus asper, 1 to 20 parts of fructus aurantii immaturus, 1 to 20 parts of sudden smile powder, 1 to 20 parts of raw hawthorn fruit, 1 to 20 parts of oyster shell, 1 to 20 parts of spreading hedyotis herb, 1 to 20 parts of zedoary and 1 to 20 parts of over 95 percent edible ethanol. The medicament can be used for oral administration and absorbed by the spleen and stomach and can be used for external use and absorbed by skin, and can be absorbed complexly in two modes of oral administration and external use. The medicament has the advantages of addressing both the symptoms and root causes along with reasonable formula, simple compatibility and definite curative effect, and is particularly suitable for infecund patients caused by blood stasis and qi depression and phlegm-damp stagnation. The invention also provides a preparation method of the medicament.
Description
Technical field
The invention belongs to the field of Chinese medicines, medicine of the treatment hysteromyoma of particularly a kind of oral administration or external and preparation method thereof.
Background technology
Hysteromyoma claims leiomyoma of uterus again, is the modal a kind of benign tumors of female sex organs.How asymptomatic, minority shows as vaginal hemorrhage, and abdominal part touches swollen thing and pressure symptom etc., can cause pain during as generation torsion of pedicle or other situations.Common with multiple myomata.Infertile, miscarriage that hysteromyoma can cause, menorrhagia, secondary anemia, and sexual dysfunction etc.The definite etiology unknown of hysteromyoma may be too high with body inner estrogen level, and it is relevant stimulated by estrogen.Because the hysteromyoma growth is very fast, when blood supply is bad, different denaturation can take place.Muscular tumor is bigger, and ischemia is more serious, and then secondary degeneration the more.
The traditional Chinese medical science thinks that hysteromyoma forms because of internal injury caused by excess of seven emotions, visceral dysfunction, qi depression to blood stasis.The traditional Chinese medical science can be divided into following two kinds of pattern of syndrome according to clinical symptoms: 1, syndrome of qi stagnation and blood stasis: the lighter's eumenorrhea, weight person is collapsed or persistent vaginal bloody discharge through promoting the circulation of blood, distending pain of the breast, lower abdomen is done to expand or dull pain, the podex bearing down is arranged, dimly red tongue, there is the purpura point on the limit, deep and stringy pulse or carefully puckery.2, syndrome of hyperactivity of fire due to deficiency of YIN: preceeded menorrhea, collapse or persistent vaginal bloody discharge through promoting the circulation of blood, scorching hot in the heart, or feel heat in the lower abdomen, nipple is itched or twinge, or distending pain of the breast leads and axillary fossa, and through the back leucorrhea with red and white discharge, or HUANGBAI(sic) is assorted mutually, red tongue, tongue is lacked Tianjin or BOHUANG, stringy and thready pulse or count accurately.
Chinese patent CN200410083835.4 discloses a kind of Chinese medicine composition that is used for the treatment of hysteromyoma, mainly is made up of Sargassum, rhizoma sparganic, Herba Duchesneae Indicae, Herba Salviae Chinensis, Herba Scutellariae Barbatae, Rhizoma Bistortae, can also add Radix Codonopsis, Rhizoma Dioscoreae, Fructus Setariae Germinatus, Radix Glycyrrhizae.Said composition can be prepared into various clinical acceptable forms, Chinese patent CN200510200765.0 discloses a kind of dispersible tablets of Chinese medicine preparation for the treatment of hysteromyoma, and it is to be prepared from Radix Et Rhizoma Rhei 240g, Eupolyphaga Seu Steleophaga 200g, Hirudo 200g, Semen Persicae 180g, Pollen Typhae 160g, Radix Scutellariae 120g, Fructus Aurantii Immaturus 180g, Concha Ostreae 240g, Radix Rehmanniae 240g, Radix Paeoniae Alba 180g, Radix Glycyrrhizae 60g and suitable adjuvant.Chinese patent CN200710065486.7 discloses a kind of Chinese medicine preparation for the treatment of hysteromyoma, is raw material with 10 flavor Chinese herbal medicine such as stir-baked RHIZOMA SPARGANII with vinegar, stir-baked RHIIZOMA CURCUMAE with vinegar, Eupolyphaga Seu Steleophaga, vinegar Squama Manis, Bulbus Fritillariae Thunbergii and Ramulus Cinnamomi.
The Chinese medicine product of above-mentioned treatment hysteromyoma is paid attention to regulating too much, has reduced the medicine proportion of a therapeutical effect relatively, has influenced the pharmic function performance, so effect is slow, the course of treatment is long, and effect is undesirable.And existing Chinese medicine oral administration but can not external, but can not the taking orally again of external, route of administration is single, makes the patient slow to the absorption of medicine.Chinese medicine for oral administration not only absorbs slowly, and causes spleen injury easily, even increase the weight of the state of an illness for the patient of weakness of the spleen and stomach.
Chinese medicine is taken difficulty owing to mostly be decoction or the pill that boils than Western medicine, has also influenced the popularization of Chinese medicine widely.
Summary of the invention
The objective of the invention is to overcome the defective that prior art exists, a kind of reasonable recipe is provided, compatibility is simplified, the medicine of the treatment hysteromyoma of determined curative effect, treating both the principal and secondary aspects of a disease, to control, control foster combination, and this medicine can take orally by taste absorb again can external by skin absorbs, can also oral administration and externally used dual mode composite absorption.This compound administering mode helps the efficient absorption of human body to medicine, and for the crowd of weakness of the spleen and stomach, the medicine that is busy with one's work, spares oneself provides multiple choices, especially the patient by the modern job crowd is accepted.
Technical scheme of the present invention is as follows:
A kind of medicine for the treatment of hysteromyoma, it is characterized in that it mainly is to be made by the raw material of following weight portion: 1 ~ 20 part of Flos Rosae Rugosae, 1 ~ 20 part of CitrusaurantiumL.Var.amara Engl., 1 ~ 20 part of Radix Angelicae Sinensis, 1 ~ 20 part of Radix Paeoniae Rubra, 1 ~ 20 part of Rhizoma Chuanxiong, tangerine 1 ~ 20 part, 1 ~ 20 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 ~ 20 part of Radix Glycyrrhizae Preparata, 1 ~ 20 part of Rhizoma Cyperi (processed), 1 ~ 20 part of Radix Scrophulariae, 1 ~ 20 part of Bulbus Fritillariae Thunbergii, 1 ~ 20 part of Radix Dipsaci, 1 ~ 20 part of Fructus Aurantii, 1 ~ 20 part of SHIXIAO SAN, 1 ~ 20 part of Fructus Crataegi, 1 ~ 20 part of Concha Ostreae, 1 ~ 20 part of Herba Hedyotidis Diffusae, 1 ~ 20 part of Rhizoma Curcumae, content are 1 ~ 20 part of edible ethanol more than 95%.
Further, the consumption of each component of medicine of the present invention is: 15 ~ 20 parts of Flos Rosae Rugosaes, 15 ~ 20 parts of CitrusaurantiumL.Var.amara Engl.s, 15 ~ 20 parts of Radix Angelicae Sinensis, 15 ~ 20 parts of Radix Paeoniae Rubra, 15 ~ 20 parts of Rhizoma Chuanxiongs, tangerine 15 ~ 20 parts, 15 ~ 20 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 15 ~ 20 parts of Radix Glycyrrhizae Preparatas, 15 ~ 20 parts of Rhizoma Cyperi (processed), 15 ~ 20 parts of Radix Scrophulariae, 15 ~ 20 parts of Bulbus Fritillariae Thunbergiis, 15 ~ 20 parts of Radix Dipsacis, 15 ~ 20 parts of Fructus Aurantiis, 15 ~ 20 parts of SHIXIAO SAN, 15 ~ 20 parts of Fructus Crataegi, 15 ~ 20 parts of Concha Ostreaes, 15 ~ 20 parts of Herba Hedyotidis Diffusaes, 15 ~ 20 parts of Rhizoma Curcumae, content are 15 ~ 20 parts of edible ethanols more than 95%.
The middle survival dose of above compatibility is the crude drug amount.
In order to strengthen the transdermal effect of medicine, can also mix transdermal agent in the medicine of the present invention, preferably weight portion is 1 ~ 5 part a azone.
Another object of the present invention provides manufacturing method for above mentioned medicine, it is characterized in that comprising the following steps:
A) take by weighing Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, dried tangerine peel, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Glycyrrhizae Preparata, Rhizoma Cyperi (processed), Radix Scrophulariae, Bulbus Fritillariae Thunbergii, Radix Dipsaci, Fructus Aurantii, SHIXIAO SAN, Fructus Crataegi, Concha Ostreae, Herba Hedyotidis Diffusae and the Rhizoma Curcumae of described weight proportion, according to the conventional extracting method of Chinese medicine, the extract of the former medicine that obtains respectively respectively to distinguish the flavor of;
B) under the room temperature, get the deionized water of 5 ~ 6 times of amounts, the content that adds described weight proportion is the edible ethanol more than 95%, is mixed with aqueous solution of alcohol;
C) with in the above-mentioned aqueous solution of alcohol of the extract obtained adding of step a, stirred 120 minutes, precipitate 2 ~ 4 hours, filter, gained filtrate sterilization, fill according to quantity must be treated the medicine of hysteromyoma.
Further, among the step c, can add in the aqueous solution of alcohol together by azone step a is extract obtained and 1 ~ 5 weight portion.
The conventional extracting method of described Chinese crude drug can adopt decocting method, circumfluence method, infusion process, percolation, semi-bionic extraction, supercritical fluid extraction, microwave extraction method etc. according to the kind of medical material.
The present invention is directed to the characteristics of hysteromyoma, select Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, dried tangerine peel, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Glycyrrhizae Preparata, Rhizoma Cyperi (processed), Radix Scrophulariae, Bulbus Fritillariae Thunbergii, Radix Dipsaci, Fructus Aurantii, SHIXIAO SAN, Fructus Crataegi, Concha Ostreae, Herba Hedyotidis Diffusae, Rhizoma Curcumae for use, with being that edible ethanol more than 95% mixes with content after each flavor Chinese medicine extraction, make to contain pure Chinese medicine extraction liquid.Employing to be to control, and control and support bonded method, but not only also external of oral administration of the medicine of making is a kind of reasonable recipe, and compatibility is simplified, the medicine of the treatment hysteromyoma of determined curative effect, treating both the principal and secondary aspects of a disease.
Chinese angelica blood supplementing and blood, menstruction regulating and pain relieving is moisturized laxation.The Radix Paeoniae Rubra clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.The Rhizoma Chuanxiong activating QI to alleviate the depression, the method wind-dryness is wet, promoting blood circulation and stopping pain.Tangerine expectorant, promoting the circulation of QI, alleviating distention in middle-JIAO, eliminating stagnation.The expectorant of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) preventing or arresting vomiting, detoxifcation, change taste.The Radix Glycyrrhizae Preparata nourishing YIN and benefiting blood, QI invigorating warming YANG, the multiple arteries and veins of only throbbing with fear.Rhizoma Cyperi (processed) is regulated the flow of vital energy and blood, tonifying blood and regulating menstruation.Radix Scrophulariae removing heat from blood YIN nourishing, eliminating fire and detoxication.The Bulbus Fritillariae Thunbergii removing heat-phlegm, powder detoxifcation.Metrorrhagia is hindered, ended to Radix Dipsaci invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous folding.The Fructus Aurantii dispelling the stagnated QI, row expectorant, removing food stagnancy.The SHIXIAO SAN blood circulation promoting and blood stasis dispelling, removing obstruction for relieving pain.Fructus Crataegi helps digestion long-pending, dissipating blood stasis blood.The Concha Ostreae yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission reduces phlegm, softening the hard mass.The Herba Hedyotidis Diffusae heat clearing away, dampness removing, detoxifcation.Rhizoma Curcumae circulation of qi promoting removing blood stasis, the removing food stagnancy pain relieving.
Hysteromyoma often influences women's fertility, causes infertile.Medicine of the present invention is applicable to that card belongs to stagnation of QI and blood, phlegm dampness obstruction pattern causes infertile person.With activating QI to eliminate phlegm such as dried tangerine peel, Radix Glycyrrhizae, the Rhizoma Pinelliae (ERCHEN TANG is removed Poria), Rhizoma Cyperi, the Fructus Crataegi fat that disappears; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Rhizoma Curcumae, Radix Scrophulariae, Bulbus Fritillariae Thunbergii, Concha Ostreae, SHIXIAO SAN blood circulation promoting and blood stasis dispelling ， Xiao Disorder pain relieving; Though the Herba Hedyotidis Diffusae muscular tumor that disappears simply wherein is bitter cold and do not have the fraud that injures one's stomach.Full side's blood circulation promoting and blood stasis dispelling, activating QI to eliminate phlegm, Xiao Disorder pain relieving.In order to do gas along expectorantization, Yu Qu Disorder disappears and pain is ended, this moment, regulating menstruation asked son from when at one stroke and merit again.
Flos Rosae Rugosae regulate the flow of vital energy resolving depression and blood dissipating blood stasis; The CitrusaurantiumL.Var.amara Engl. the chest stuffiness relieving of regulating the flow of vital energy, dispersing the stagnated liver-QI for regulating the stomach, appetizing preventing or arresting vomiting.Two medicines, 5 usefulness, a gas one blood, QI and blood is two transfers, eliminating turbid pathogen with aromatics, the appetizing of being amusing, the strength enhancing that absorbs the drug when oral.Content is the edible ethanol blood circulation promoting and blood stasis dispelling more than 95%, promotes that drug osmotic to cell absorbs, and auxiliary taste absorb to improve curative effect when oral; Outer time spent skin expansion pore is to strengthen the drug transdermal trap.
Medicine of the present invention can also be smeared abdominal part with medicine of the present invention except for oral administration, and the efficacy of a drug sick institute that goes directly so can remove the patient suffering, obtains and imitates in no time.This medicine is applicable to that also whole body smears.Adopt oral administration and externally usedly, drug effect is more remarkable.
It is obvious that the present invention treats the hysteromyoma curative effect, and clinical usefulness repeatly, effect are very prompt, generally serve on about 30 doses and can heal or produce effects.Medicine of the present invention is through clinical 93 routine patients' clinical verification, and curing number is 72 examples, and significant figure is 11 examples, and invalid number is 10 examples, and total effective rate reaches 92.4%.Do not see toxic side effect in the therapeutic process, the patient has better curative effect to obstinate.For further specifying therapeutic effect, it is as follows now to enumerate model case:
Case 1: certain woman, 31 years old, vaginal hemorrhage, aching pain in waist and back, constipation often.Suffers from hysteromyoma after diagnosing.Through the western medical treatment poor effect.Oral medicine of the present invention, each 10 milliliters, every day 3 times, above symptom was alleviated in 12 days, eliminated in 60 days.Paying a return visit after 3 months does not have recurrence.
Case 2: certain woman, 40 years old, vaginal hemorrhage, menostaxis, anemia often.Suffers from hysteromyoma after diagnosing.External medicine of the present invention is smeared whole body and abdominal part, and every day 2 times, each 10 milliliters, repeatedly smear at the abdominal part place.Above symptom was alleviated in 10 days, eliminated in 55 days.Paying a return visit after 6 months does not have recurrence.
Case 3: certain woman, 35 years old, menorrhagia, menostaxis, anemia, frequent micturition, aching pain in waist and back.Once took the Chinese medicine of multiple treatment hysteromyoma, but effect is all not good.Oral medicine of the present invention, each 10 milliliters, every day 3 times; This medicine of external is smeared whole body and abdominal part, and every day 2 times, each 10 milliliters, repeatedly smear at the abdominal part place.Above symptom is oral to be alleviated with external 8, eliminates in 45 days.Paying a return visit after 7 months does not have recurrence.
The specific embodiment
Embodiment 1
Take by weighing 15 parts of Flos Rosae Rugosaes, 18 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Rubra, 17 parts of Rhizoma Chuanxiongs, tangerine 19 parts, 16 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 19 parts of Radix Glycyrrhizae Preparatas, 17 parts of Rhizoma Cyperi (processed), 18 parts of Radix Scrophulariae, 18 parts of Bulbus Fritillariae Thunbergiis, 15 parts of Radix Dipsacis, 15 parts of Fructus Aurantiis, 16 parts of SHIXIAO SAN, 20 parts of Fructus Crataegi, 18 parts of Concha Ostreaes, 19 parts of Herba Hedyotidis Diffusaes, 15 parts of Rhizoma Curcumae adopt the method that decocts the back concentrating under reduced pressure to make Chinese medicine extract respectively, and are standby.
Under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add content and be 18 parts of 96% edible ethanols, be mixed with aqueous solution of alcohol, standby.
Above-mentioned various Chinese medicine extract are added in the aqueous solution of alcohol, fully stirred 120 minutes, precipitate 2 ~ 4 hours, supernatant 200 orders filter, and gained filtrate is the medicine of the treatment hysteromyoma of oral administration or external, carries out fill under aseptic condition.Gained precipitate and filtering residue focus on.
Embodiment 2
The drug component proportioning is: 18 parts of Flos Rosae Rugosaes, 19 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Radix Angelicae Sinensis, 18 parts of Radix Paeoniae Rubra, 20 parts of Rhizoma Chuanxiongs, tangerine 20 parts, 19 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 18 parts of Radix Glycyrrhizae Preparatas, 20 parts of Rhizoma Cyperi (processed), 19 parts of Radix Scrophulariae, 19 parts of Bulbus Fritillariae Thunbergiis, 19 parts of Radix Dipsacis, 18 parts of Fructus Aurantiis, 18 parts of SHIXIAO SAN, 18 parts of Fructus Crataegi, 19 parts of Concha Ostreaes, 20 parts of Herba Hedyotidis Diffusaes, 20 parts of Rhizoma Curcumae, content are 18 parts of 97% edible ethanols.Other is identical with embodiment 1.
Embodiment 3
The drug component proportioning is: 19 parts of Flos Rosae Rugosaes, 20 parts of CitrusaurantiumL.Var.amara Engl.s, 20 parts of Radix Angelicae Sinensis, 19 parts of Radix Paeoniae Rubra, 19 parts of Rhizoma Chuanxiongs, tangerine 19 parts, 20 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 19 parts of Radix Glycyrrhizae Preparatas, 20 parts of Rhizoma Cyperi (processed), 19 parts of Radix Scrophulariae, 19 parts of Bulbus Fritillariae Thunbergiis, 19 parts of Radix Dipsacis, 20 parts of Fructus Aurantiis, 20 parts of SHIXIAO SAN, 20 parts of Fructus Crataegi, 20 parts of Concha Ostreaes, 20 parts of Herba Hedyotidis Diffusaes, 19 parts of Rhizoma Curcumae, content are 18 parts of 98% edible ethanols.Other is identical with embodiment 1.
Embodiment 4
The drug component proportioning is: 16 parts of Flos Rosae Rugosaes, 16 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Radix Angelicae Sinensis, 17 parts of Radix Paeoniae Rubra, 18 parts of Rhizoma Chuanxiongs, tangerine 16 parts, 17 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 16 parts of Radix Glycyrrhizae Preparatas, 18 parts of Rhizoma Cyperi (processed), 19 parts of Radix Scrophulariae, 17 parts of Bulbus Fritillariae Thunbergiis, 18 parts of Radix Dipsacis, 16 parts of Fructus Aurantiis, 18 parts of SHIXIAO SAN, 19 parts of Fructus Crataegi, 16 parts of Concha Ostreaes, 16 parts of Herba Hedyotidis Diffusaes, 18 parts of Rhizoma Curcumae, content are 16 parts of 99% edible ethanols.Other is identical with embodiment 1.
Embodiment 5
The drug component proportioning is: 17 parts of Flos Rosae Rugosaes, 19 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Radix Angelicae Sinensis, 17 parts of Radix Paeoniae Rubra, 20 parts of Rhizoma Chuanxiongs, tangerine 18 parts, 19 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 18 parts of Radix Glycyrrhizae Preparatas, 17 parts of Rhizoma Cyperi (processed), 20 parts of Radix Scrophulariae, 20 parts of Bulbus Fritillariae Thunbergiis, 18 parts of Radix Dipsacis, 18 parts of Fructus Aurantiis, 19 parts of SHIXIAO SAN, 16 parts of Fructus Crataegi, 17 parts of Concha Ostreaes, 19 parts of Herba Hedyotidis Diffusaes, 20 parts of Rhizoma Curcumae, content are 20 parts of 100% edible ethanols.Other is identical with embodiment 1.
Embodiment 6
The drug component proportioning is: 18 parts of Flos Rosae Rugosaes, 20 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Radix Angelicae Sinensis, 19 parts of Radix Paeoniae Rubra, 19 parts of Rhizoma Chuanxiongs, tangerine 20 parts, 18 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 17 parts of Radix Glycyrrhizae Preparatas, 18 parts of Rhizoma Cyperi (processed), 18 parts of Radix Scrophulariae, 18 parts of Bulbus Fritillariae Thunbergiis, 18 parts of Radix Dipsacis, 18 parts of Fructus Aurantiis, 19 parts of SHIXIAO SAN, 18 parts of Fructus Crataegi, 18 parts of Concha Ostreaes, 19 parts of Herba Hedyotidis Diffusaes, 18 parts of Rhizoma Curcumae, content are 19 parts of 97% edible ethanols.Other is identical with embodiment 1.
Claims (5)
1. medicine for the treatment of hysteromyoma, it is characterized in that it mainly is to be made by the raw material of following weight portion: 1 ~ 20 part of Flos Rosae Rugosae, 1 ~ 20 part of CitrusaurantiumL.Var.amara Engl., 1 ~ 20 part of Radix Angelicae Sinensis, 1 ~ 20 part of Radix Paeoniae Rubra, 1 ~ 20 part of Rhizoma Chuanxiong, tangerine 1 ~ 20 part, 1 ~ 20 part of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), 1 ~ 20 part of Radix Glycyrrhizae Preparata, 1 ~ 20 part of Rhizoma Cyperi (processed), 1 ~ 20 part of Radix Scrophulariae, 1 ~ 20 part of Bulbus Fritillariae Thunbergii, 1 ~ 20 part of Radix Dipsaci, 1 ~ 20 part of Fructus Aurantii, 1 ~ 20 part of SHIXIAO SAN, 1 ~ 20 part of Fructus Crataegi, 1 ~ 20 part of Concha Ostreae, 1 ~ 20 part of Herba Hedyotidis Diffusae, 1 ~ 20 part of Rhizoma Curcumae, content are 1 ~ 20 part of edible ethanol more than 95%.
2. medicine as claimed in claim 1, it is characterized in that it mainly is to be made by the raw material of following weight portion: 15 ~ 20 parts of Flos Rosae Rugosaes, 15 ~ 20 parts of CitrusaurantiumL.Var.amara Engl.s, 15 ~ 20 parts of Radix Angelicae Sinensis, 15 ~ 20 parts of Radix Paeoniae Rubra, 15 ~ 20 parts of Rhizoma Chuanxiongs, tangerine 15 ~ 20 parts, 15 ~ 20 parts of Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens)s, 15 ~ 20 parts of Radix Glycyrrhizae Preparatas, 15 ~ 20 parts of Rhizoma Cyperi (processed), 15 ~ 20 parts of Radix Scrophulariae, 15 ~ 20 parts of Bulbus Fritillariae Thunbergiis, 15 ~ 20 parts of Radix Dipsacis, 15 ~ 20 parts of Fructus Aurantiis, 15 ~ 20 parts of SHIXIAO SAN, 15 ~ 20 parts of Fructus Crataegi, 15 ~ 20 parts of Concha Ostreaes, 15 ~ 20 parts of Herba Hedyotidis Diffusaes, 15 ~ 20 parts of Rhizoma Curcumae, content are 15 ~ 20 parts of edible ethanols more than 95%.
3. medicine as claimed in claim 1 or 2 is characterized in that described medicine comprises that also weight portion is 1 ~ 5 part a azone.
4. the preparation method of the described medicine of one of claim 1 to 3 is characterized in that comprising the following steps:
A) take by weighing Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, dried tangerine peel, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Glycyrrhizae Preparata, Rhizoma Cyperi (processed), Radix Scrophulariae, Bulbus Fritillariae Thunbergii, Radix Dipsaci, Fructus Aurantii, SHIXIAO SAN, Fructus Crataegi, Concha Ostreae, Herba Hedyotidis Diffusae and the Rhizoma Curcumae of described weight proportion, according to the conventional extracting method of Chinese medicine, the extract of the former medicine that obtains respectively respectively to distinguish the flavor of;
B) under the room temperature, get the deionized water of 5 ~ 6 times of amounts, the content that adds described weight proportion is the edible ethanol more than 95%, is mixed with aqueous solution of alcohol;
C) with in the above-mentioned aqueous solution of alcohol of the extract obtained adding of step a, stirred 120 minutes, precipitate 2 ~ 4 hours, filter, gained filtrate sterilization, fill according to quantity must be treated the medicine of hysteromyoma.
5. preparation method as claimed in claim 4 is characterized in that, among the step c, azone step a is extract obtained and described weight proportion adds aqueous solution of alcohol together.
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Cited By (9)
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| CN102247581A (en) * | 2011-08-18 | 2011-11-23 | 王思曾 | Medicament for treating myoma of uterus |
| CN103385953A (en) * | 2013-07-18 | 2013-11-13 | 上海中医药大学附属岳阳中西医结合医院 | A traditional Chinese medicine composition for the treatment of menopausal uterine fibroids and applications thereof |
| CN103599271A (en) * | 2013-11-26 | 2014-02-26 | 孙元盛 | Traditional Chinese medicine for treating hysteromyoma |
| CN103893336A (en) * | 2014-03-26 | 2014-07-02 | 孙忠云 | Traditional Chinese medicine enema for treating salpinx obstructive infertility caused by qi stagnation and blood stasis and nursing method using same |
| CN104306872A (en) * | 2014-09-22 | 2015-01-28 | 朱艳茹 | Traditional Chinese medicine for treating uterine fibroid |
| CN105797026A (en) * | 2016-05-06 | 2016-07-27 | 陈彬 | Traditional Chinese medicine composition for treating blood stasis type hysteromyoma and preparation method thereof |
| CN105963546A (en) * | 2016-05-06 | 2016-09-28 | 陈彬 | Traditional Chinese medicinal composition for treating phlegm-dampness type uterine fibroids and preparation method of traditional Chinese medicinal composition |
| CN106880823A (en) * | 2017-04-27 | 2017-06-23 | 徐士魁 | It is a kind of to treat medicine of endometriosis and preparation method thereof |
| CN108704100A (en) * | 2018-06-04 | 2018-10-26 | 浙江中医药大学 | A kind of Chinese medicine dietary product for treating tubercle |
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| 《当代妇科名医名方》 20091130 刘兰芳 等 理气逐瘀消脂汤 金盾出版社 406 1-5 , 1 * |
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| CN103385953B (en) * | 2013-07-18 | 2015-04-08 | 上海中医药大学附属岳阳中西医结合医院 | A traditional Chinese medicine composition for the treatment of menopausal uterine fibroids and applications thereof |
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| CN104306872A (en) * | 2014-09-22 | 2015-01-28 | 朱艳茹 | Traditional Chinese medicine for treating uterine fibroid |
| CN105797026A (en) * | 2016-05-06 | 2016-07-27 | 陈彬 | Traditional Chinese medicine composition for treating blood stasis type hysteromyoma and preparation method thereof |
| CN105963546A (en) * | 2016-05-06 | 2016-09-28 | 陈彬 | Traditional Chinese medicinal composition for treating phlegm-dampness type uterine fibroids and preparation method of traditional Chinese medicinal composition |
| CN106880823A (en) * | 2017-04-27 | 2017-06-23 | 徐士魁 | It is a kind of to treat medicine of endometriosis and preparation method thereof |
| CN108704100A (en) * | 2018-06-04 | 2018-10-26 | 浙江中医药大学 | A kind of Chinese medicine dietary product for treating tubercle |
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