CN102247581B - Medicament for treating myoma of uterus - Google Patents
Medicament for treating myoma of uterus Download PDFInfo
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- CN102247581B CN102247581B CN 201110237700 CN201110237700A CN102247581B CN 102247581 B CN102247581 B CN 102247581B CN 201110237700 CN201110237700 CN 201110237700 CN 201110237700 A CN201110237700 A CN 201110237700A CN 102247581 B CN102247581 B CN 102247581B
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Abstract
The invention discloses a medicament for treating myoma of uterus. The medicament is prepared by the following steps of: uniformly mixing vinegar-baked bupleurum root, vinegar-baked nutgrass galingale rhizome, angelica, szechuan lovage rhizome, peach kernel, common burreed rhizome, zedoary, root of red-rooted salvia, red paeony root, scrophularia, selfheal spike, root bark of the peony tree, leech, bulbus fritillariae thunbergii and licorice root which are selected and cleaned by using clear water; crushing the raw materials into 100-mesh to 120-mesh medicinal powder; and preparing a watered pill product by taking pure water as an adhesive according to the conventional method. The medicament has the effects of soothing the liver and regulating vital energy, promoting blood circulation to remove blood stasis, eliminating stagnation and removing swelling; and the aims of quick response to treatment of the myoma of uterus, low side effect and low cost are fulfilled.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of hysteromyoma, particularly relate to a kind of medicine of the treatment hysteromyoma for preparing take Chinese medicine as crude drug.
Background technology
Hysteromyoma (Hysteromyoma) claim again leiomyoma of uterus, is the modal a kind of benign tumors of female sex organs.How asymptomatic, minority shows as vaginal hemorrhage, and abdominal part touches swollen thing and pressure symptom etc.As can cause pain when torsion of pedicle or other situations occur, common with multiple myomata.
Hysteromyoma is very large to women's harm, may cause the situations such as infertile, suppurative inflammation, canceration such as untimely treatment, has had a strong impact on the healthy of women.
The treatment primary disease mainly passes through the methods such as operative treatment, Drug therapy at present, but these methods are expensive, patient is painful large.
Summary of the invention
The purpose of this invention is to provide a kind of medicine for the treatment of hysteromyoma, this medicine is comprised of Chinese medicine, has the effect of depressed liver-energy dispersing and QI regulating, activating blood circulation to dissipate blood stasis, mass dissipating and swelling eliminating, can play instant effect, side effect is little, expense is low purpose to the treatment of hysteromyoma.
Medicine of the present invention is that the Chinese medicine by following parts by weight is that crude drug prepares:
Radix Bupleuri (processed with vinegar) 8～12 Rhizoma Cyperi (processed with vinegar) 8～12 Radix Angelicae Sinensis 8～12
Rhizoma Chuanxiong 8～12 Semen Persicaes 8～12 rhizoma sparganic 12～18
Rhizoma Curcumae 12～18 Radix Salviae Miltiorrhizaes 24～36 Radix Paeoniae Rubra 12～18
Radix Scrophulariae 12～18 Spica Prunellaes 12～18 Cortex Moutans 12～18
Hirudo 3～5 Bulbus Fritillariae Thunbergii 12～18 Radix Glycyrrhizaes 4～8.
Said medicine can be made any dosage form on the pharmaceutics, such as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is watered pill.
The concrete preparation method of medicine of the present invention being made watered pill is:
Said medicine is cleaned mix homogeneously by described parts by weight, be ground into 100～120 medicated powder, make binding agent with pure water, make according to a conventional method the watered pill product.
The traditional Chinese medical science thinks that hysteromyoma mainly is because of feelings will internal injury, visceral dysfunction, and qi stagnation blood stasis forms.The Therapeutic Principle should be depressed liver-energy dispersing and QI regulating, activating blood circulation to dissipate blood stasis, mass dissipating and swelling eliminating.The Radix Bupleuri (processed with vinegar) dispersing the stagnated live-QI to relieve the stagnation of QI, regulate the flow of vital energy and blood; Rhizoma Cyperi (processed with vinegar) depressed liver-energy dispersing and QI regulating, eliminating stagnation repercussive; Chinese angelica blood supplementing is invigorated blood circulation, the blood stasis dispelling regulating menstruation; Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression; Semen Persicae blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating; Rhizoma sparganic removing blood stasis, circulation of qi promoting removing food stagnancy; Rhizoma Curcumae removing blood stasis, circulation of qi promoting removing food stagnancy; Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle; Capable stagnant, the promoting blood circulation to restore menstrual flow of Radix Paeoniae Rubra blood stasis dispelling; Radix Scrophulariae heat-clearing and toxic substances removing, eliminating stagnation eliminating carbuncle; Spica Prunellae clearing away liver-fire, Disperse hepatic depression; Cortex Moutan clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; The Hirudo removing blood stasis; Bulbus Fritillariae Thunbergii clearing heat for detumescence, dissipating phlegm and resolving masses; Radix Glycyrrhizae invigorating the spleen and replenishing QI, the mitigation property of medicine.All medicines share, and can play the effect of depressed liver-energy dispersing and QI regulating, activating blood circulation to dissipate blood stasis, mass dissipating and swelling eliminating.The treatment that is used for the treatment of hysteromyoma can be played instant effect, side effect is little, expense is low purpose.
For further investigating clinical efficacy and the safety of medicine of the present invention, select 32 patients with uterin leiomyoma patients that the curative effect of medicine of the present invention has been carried out clinical observation.
32 routine cases are divided into two groups at random, treatment group 15 examples, matched group 17 examples.All cases all according to the diagnostic criteria of " new Chinese medicine guideline of clinical investigations (first volume) ", is diagnosed as hysteromyoma.
Diagnostic criteria
Hysteromyoma is divided into three types:
1), intramural myoma: grow in the Uterus wall Musclar layer, be this type of when just falling ill, often affect the contractility in uterus, cause through blood volume and increase, menostaxis, clinical the most common;
2), Subserous myoma: give prominence to the surface, uterus, directly contact the eumenorrhea with serous coat;
3), fleshy polyp: to the intrauterine growth, directly contact with mucous layer, sometimes may grow from cavity of uterus and reach intravaginal, often form band base of a fruit muscular tumor, the easiest causing bleeding;
Can make a definite diagnosis according to gynecologic inspection and B ultrasonic, CT examination.
Therapeutic Method
Matched group adopts the danazol capsule, and is oral, one time 1,2 times on the one.Treatment group adopts watered pill medicine of the present invention to treat, every day 3 times, each 10 grams.30 days is a course for the treatment of, uses altogether 2 courses for the treatment of.
Criterion of therapeutical effect
According to the criterion of therapeutical effect of " new Chinese medicine guideline of clinical investigations (first volume) ", recovery from illness: muscular tumor disappears, clinical symptom disappearance.Effectively: 1/3 above person is dwindled in sx↓ or disappearance, muscular tumor; Or muscular tumor is stable after the drug withdrawal, and transference cure continues above person half a year; Invalid: symptom has no obviously and dwindles without change, muscular tumor.
The curative effect comparative result sees Table 1 after two groups of case treatments.
Curative effect relatively after the table 1 liang group case treatment
| Group | The example number | Recovery from illness n(%) | Effective n(%) | Invalid n(%) | Total effective rate n(%) |
| Matched group | 17 | 3（17.6） | 8（47.1） | 6（35.3） | 11（64.7） |
| Treatment group | 15 | 4（26.7） | 8（53.3） | 3（20） | 12（80） |
Statistical result showed, the treatment group curative effect obviously is better than matched group, and two group differences are remarkable,
P＜0.05.
The specific embodiment
Embodiment 1
Get Radix Bupleuri (processed with vinegar) 80g, Rhizoma Cyperi (processed with vinegar) 80g, Radix Angelicae Sinensis 80g, Rhizoma Chuanxiong 80g, Semen Persicae 80g, rhizoma sparganic 120g, Rhizoma Curcumae 120g, Radix Salviae Miltiorrhizae 240g, Radix Paeoniae Rubra 120g, Radix Scrophulariae 120g, Spica Prunellae 120g, Cortex Moutan 120g, Hirudo 30g, Bulbus Fritillariae Thunbergii 120g, Radix Glycyrrhizae 40g mix homogeneously selected, that clear water is cleaned, be ground into 100～120 medicated powder, make binding agent with pure water, make according to a conventional method the watered pill and produce the agent product.
Embodiment 2
Get Radix Bupleuri (processed with vinegar) 120g, Rhizoma Cyperi (processed with vinegar) 120g, Radix Angelicae Sinensis 120g, Rhizoma Chuanxiong 120g, Semen Persicae 120g, rhizoma sparganic 180g, Rhizoma Curcumae 180g, Radix Salviae Miltiorrhizae 360g, Radix Paeoniae Rubra 180g, Radix Scrophulariae 180g, Spica Prunellae 180g, Cortex Moutan 180g, Hirudo 50g, Bulbus Fritillariae Thunbergii 180g, Radix Glycyrrhizae 80g mix homogeneously selected, that clear water is cleaned, be ground into 100～120 medicated powder, make binding agent with pure water, make according to a conventional method the watered pill product.
Claims (2)
1. medicine for the treatment of hysteromyoma is that crude drug prepares by the Chinese medicine of following portions by weight:
Radix Bupleuri (processed with vinegar) 8～12 Rhizoma Cyperi (processed with vinegar) 8～12 Radix Angelicae Sinensis 8～12
Rhizoma Chuanxiong 8～12 Semen Persicaes 8～12 rhizoma sparganic 12～18
Rhizoma Curcumae 12～18 Radix Salviae Miltiorrhizaes 24～36 Radix Paeoniae Rubra 12～18
Radix Scrophulariae 12～18 Spica Prunellaes 12～18 Cortex Moutans 12～18
Hirudo 3～5 Bulbus Fritillariae Thunbergiis 12～18 Radix Glycyrrhizaes 4～8.
2. the medicine for the treatment of hysteromyoma according to claim 1 is characterized in that described medicine is made watered pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110237700 CN102247581B (en) | 2011-08-18 | 2011-08-18 | Medicament for treating myoma of uterus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110237700 CN102247581B (en) | 2011-08-18 | 2011-08-18 | Medicament for treating myoma of uterus |
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| Publication Number | Publication Date |
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| CN102247581A CN102247581A (en) | 2011-11-23 |
| CN102247581B true CN102247581B (en) | 2013-03-27 |
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| CN 201110237700 Expired - Fee Related CN102247581B (en) | 2011-08-18 | 2011-08-18 | Medicament for treating myoma of uterus |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579997B (en) * | 2012-03-20 | 2014-03-05 | 南宁市净雪皇生物工程有限公司 | Traditional Chinese medicine proved recipe for treating hysteromyoma |
| CN102552869B (en) * | 2012-03-20 | 2013-11-27 | 南宁市品迪生物工程有限公司 | Three-in-one comprehensive therapy for hysteromyoma |
| CN103212047A (en) * | 2013-04-22 | 2013-07-24 | 窦子云 | Traditional Chinese medicine composition for treating hysteromyoma and ovarian cysts |
| CN103990071A (en) * | 2014-05-29 | 2014-08-20 | 蚌埠明日欣医药有限公司 | Traditional Chinese medicine prescription for treating myoma of uterus |
| CN104107301A (en) * | 2014-07-16 | 2014-10-22 | 赵学科 | Medicinal composition for treating hysteromyoma and preparation method thereof |
| CN105362693A (en) * | 2015-12-15 | 2016-03-02 | 青岛华之草医药科技有限公司 | Composition containing chitosan oligosaccharide and chitosan and used for treating uterine myoma |
| CN105395875A (en) * | 2015-12-15 | 2016-03-16 | 青岛华之草医药科技有限公司 | Method for preparing composition containing chitosan oligosaccharide and chitosan and treating myoma of uterus |
| CN105770374A (en) * | 2016-04-12 | 2016-07-20 | 汤华淑 | Traditional Chinese medicine composition for treating uterine fibroid |
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| CN101912585A (en) * | 2010-08-27 | 2010-12-15 | 葛德钜 | Medicament for treating myoma of uterus and preparation method thereof |
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2011
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Patent Citations (4)
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| CN101632820A (en) * | 2008-07-24 | 2010-01-27 | 郭纯 | Intestinal obstruction removal pill |
| CN101797366A (en) * | 2010-04-21 | 2010-08-11 | 孙明海 | Drug composition for treating tumor |
| CN101912585A (en) * | 2010-08-27 | 2010-12-15 | 葛德钜 | Medicament for treating myoma of uterus and preparation method thereof |
| CN102068641A (en) * | 2010-10-09 | 2011-05-25 | 李蕴 | Chinese medicinal capsules for treating gynecological diseases |
Non-Patent Citations (6)
| Title |
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| 子宫肌瘤中医药研究概况;徐文婷等;《辽宁中医药大学学报》;20101031;第12卷(第10期);205-207 * |
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