CN105727015A - Composition for regulating blood lipid and blood pressure and preparation method thereof - Google Patents
Composition for regulating blood lipid and blood pressure and preparation method thereof Download PDFInfo
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- CN105727015A CN105727015A CN201610091208.8A CN201610091208A CN105727015A CN 105727015 A CN105727015 A CN 105727015A CN 201610091208 A CN201610091208 A CN 201610091208A CN 105727015 A CN105727015 A CN 105727015A
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Classifications
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- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The invention discloses a composition for regulating blood lipid and blood pressure and a preparation method thereof. The composition is prepared from, by weight, 10-15 parts of flos lonicerae extract chlorogenic acid, 15-20 parts of nostoc fermentation powder, 10-15 parts of cortex cinnamomi stems and bark, 3-6 parts of celery seed essence, 10-15 parts of milk thistle, 10-15 parts of corn stigma, 3-10 parts of cranberries, 3-10 parts of folium ginkgo, 10-15 parts of olive leaves and 4-6 parts of propolis. The composition is based on the principle of regulating blood lipid and blood pressure of traditional Chinese medicine, the selected traditional Chinese medical materials have the effects of lowering blood pressure, blood lipid and blood sugar and improving immunity, the effect is good, no side effect is caused after the composition is eaten for a long time, and the composition can be pressed into tablets or encapsulated into capsules for preservation and is convenient to eat and carry.
Description
Technical field
The present invention relates to a kind of compositions, be specifically related to a kind of composition and method of making the same nursing one's health blood fat and blood pressure.
Background technology
Hyperlipemia refers to that blood lipid level is too high, can directly cause the disease of some serious harm healths, such as atherosclerosis, coronary heart disease, pancreatitis etc..
The cause of disease: hyperlipemia can be divided into constitutional and Secondary cases two class.Constitutional is with congenital and heredity is relevant, it is due to single-gene defect or polygenes defect, make the transhipment of participation lipoprotein and the receptor of metabolism, enzyme or apolipoprotein caused by abnormal, or cause due to environmental factors (diet, nutrition, medicine) with by the mechanism of the unknown.The multiple metabolic disorder disease (diabetes, hypertension, myxedema, hypothyroidism, obesity, hepatorenal disease, adrenal cortex function are hyperfunction) of being born in of Secondary cases, or with other factor age, sex, season, drink, smoking, diet, physical exertion, psychentonia, emotional activity etc. relevant.Clinical manifestation: the clinical manifestation of hyperlipemia is mainly lipid and deposits caused arteriosclerosis in the xanthoma caused by intradermal deposition and lipid at blood vessel endothelium.Although hyperlipemia can cause xanthoma, but its incidence rate is not significantly high；And atherosclerotic generation and development are a kind of slowly progressive processes.Therefore under normal conditions, most of patients non-evident sympton and abnormal sign.Many people are owing to just finding have blood plasma lipoprotein level to raise when other reasons carries out blood biochemical inspection.No matter it is adopt operative treatment, radiotherapy or adopt chemotherapy, all the health of patient is caused great burden, and costly, sufferer is born painful big.
The blood pressure of normal person fluctuates within the specific limits with internal and external environment change.Overall crowd, blood pressure level gradually rose with the age, becomes apparent from shrinking pressure, but after 50 years old, diastolic pressure presents downward trend, and pulse pressure also strengthens therewith.In recent years; people to cardiovascular diseases's multiple risk factors effect and the heart, brain, kidney target-organ protection understanding deepen continuously; the diagnostic criteria of hypertension is also in continuous adjustment; it is now recognized that there is the dangerous difference of cardiovascular diseases in the patient of same blood pressure level; therefore there is the concept that blood pressure is layered; namely the patient that cardiovascular diseases's risk factor is different occurs, and suitable blood pressure level should have difference.Doctor on the basis of reference standard, judges the most suitable blood pressure range of this patient according to its concrete condition, adopts remedy measures targetedly when patient.
The cause of disease: 1. custom factor heredity about half hyperpietic has family history.2. at environmental factors 3. age: sickness rate the trend increased and increase with the age, within more than 40 years old, person's sickness rate is high.4. other: overweight people's sickness rate is high；Contraceptive；Sleep Apnea-hypopnea Syndrome.Classification: hypertension can be divided into two classes clinically: 1. essential hypertension: is a kind of independent disease that the cause of disease is not yet clear and definite with blood pressure rising for main clinical manifestation.2. secondary hypertension: be also called symptomatic hypertension, in this kind of disease, the cause of disease is clear and definite, and hypertension is only one of clinical manifestation of this kind of disease, and blood pressure can temporary or persistency rising.Clinical manifestation: the symptom of hypertension varies with each individual.Early stage is likely to asymptomatic or symptom is inconspicuous, only blood pressure can be occurred after fatigue, psychentonia, anxious state of mind to raise, and recovers normal after rest.Along with the course of disease extends, blood pressure significantly continues to raise, and there will be various symptom gradually.Now it is referred to as benign hypertension.The common clinical symptoms of benign hypertension has headache, dizziness, absent minded, hypomnesis, numb limbs and tense tendons, nocturia increase, cardiopalmus, uncomfortable in chest, weak etc..Even there will be the symptoms such as severe headache, vomiting, cardiopalmus, dizziness when blood pressure is suddenly increased to a certain degree, obnubilation, tic can occur time serious.This just belongs to accelerated hypertension and hypertension critical illness, how infringement and the pathological changes of the organs such as the serious heart, brain, kidney can occur in a short time, such as apoplexy, heart infarction, renal failure etc..Symptom there is no consistent relation with the level that blood pressure raises.
Summary of the invention
For solving the problems referred to above, the invention provides a kind of composition and method of making the same nursing one's health blood fat and blood pressure.
For achieving the above object, the technical scheme that the present invention takes is:
A kind of compositions nursing one's health blood fat and blood pressure, is prepared from by the raw material of following weight portion:
Flos Lonicerae extract chlorogenic acid 10～15 parts, Nostoc yeast powder 15～20 parts, Cortex Cinnamomi peel of stem 10～15 parts, celery seed elite 3～6 parts, Milk Thistle 10～15 parts, Stigma Maydis 10～15 parts, cranberry 3～10 parts, Folium Ginkgo 3～10 parts, 10～15 parts of Folium olive, propolis 4～6 parts.
For solving the problems referred to above, the preparation method that present invention also offers a kind of compositions nursing one's health blood fat and blood pressure, comprise the steps:
S1, the aqueous solution of Flos Lonicerae extract is first passed through composite polrvinyl chloride ultrafilter membrane and carries out membrance separation, collect permeate, after by the NF membrane of molecular cut off 250 extracting solution is concentrated into the 11% of original volume again, macroporous resin column is passed through with the flow velocity of 2～6BV/h, dynamic adsorption is saturated, first colourless to effluent with the above-mentioned macroporous resin column of flow velocity drip washing of 3～11BV/h with deionized water, eluting is carried out with the flow velocity of 7～13BV/h again with the organic solvent that volume fraction is 30%～110%, collect organic solvent eluent until flowing out without chlorogenic acid, finally will collect gained eluent concentrating under reduced pressure, obtain extractum；Polyamide column is passed through with the flow velocity of 1～5BV/h by after extractum water dissolution, after dynamic adsorption is saturated, with 3～8BV deionized water above-mentioned polyamide column of flow velocity drip washing with 1～10BV/h, eluting is carried out with the flow velocity of 5～10BV/h again with the aqueous solutions of organic solvent that volume fraction is 20%～100%, collect organic solvent eluent until flowing out without chlorogenic acid, spray drying, obtains chlorogenic acid；
S2, take 60～70 portions of Nostoc, clean, wear into coarse powder with grinder, then with 85～90 DEG C of hot-water soak 85min, pull out after draining, add 15～25 parts of room temperature pure water, and even, then according to the ratio microbe inoculation leaven of inoculum concentration 1.5%, keep temperature 35～41 DEG C, ferment 48 hours, oven drying at low temperature after fermentation ends, grind to form fine powder, obtain Nostoc yeast powder；
S3, weigh Cortex Cinnamomi peel of stem 10～15 parts, Milk Thistle 10～15 parts, Stigma Maydis 10～15 parts, cranberry 3～10 parts, Folium Ginkgo 3～10 parts, 10～15 parts of Folium olive flash extracter process after, gained extracting solution first heats with high heat, heating 1～1.5h with slow fire after boiling, hollow fiber ultrafiltration membrane filters；Medicinal residues add 15～25 times of soak by water twice, and hollow fiber ultrafiltration membrane filters, and merges three filtrates, is concentrated into 1.5g/ml；It is slowly added to 90～100% organic solvents, until organic solvent concentration is 55～65%, cold preservation 8～9 hours, supernatant is removed after the centrifugal 15～25min of 2000～4000r/min, precipitate with deionized water is dissolved to original volume, with organic solvent deposit 2 times, organic solvent concentration respectively 65～75%, 75～85%；Precipitate with deionized water is dissolved to original volume, adds the solution of trichloroacetic acid that mass fraction is 10～12% of original volume 1/6～1/5 volume, fully stands 4～6h after mixing, go to precipitate to obtain supernatant after the centrifugal 15～25min of 2000～4000r/min, by gained supernatant sucking filtration, dry, obtain extract；
S4, weigh celery seed elite 3～6 parts, propolis 4～6 parts, the chlorogenic acid 10～15 parts of step S1 gained, step S2 gained Nostoc yeast powder 15～20 parts be placed in homogenizer, add the extract stirring 5～30min of step S3 gained, obtain pharmaceutical composition.
Preferably, the molecular cut off of described hollow fiber ultrafiltration membrane is 1000.
Preferably, described organic solvent is the turpentine derivatives of natural origin.
Preferably, described turpentine derivatives is the isomery of pinene, disproportionation products.
Preferably, described microbe leaven is by lactobacillus, Bacillus licheniformis, Corynebacterium glutamicum mixing gained.
Preferably, lactobacillus in described microbe leaven, Bacillus licheniformis, Corynebacterium glutamicum mass ratio be 2: 1: 2.
The method have the advantages that
The principle of blood fat and blood pressure is nursed one's health based on Chinese medicine, the Chinese medicinal material selected have reduce blood pressure, blood fat, blood glucose, raising immunity effect, and respond well, long-term edible do not have side effect, can as being pressed into tablet or fill becomes capsule to preserve, edible easy to carry.
Detailed description of the invention
In order to make objects and advantages of the present invention clearly understand, below in conjunction with embodiment, the present invention is further elaborated.Should be appreciated that specific embodiment described herein is only in order to explain the present invention, is not intended to limit the present invention.
The molecular cut off of the hollow fiber ultrafiltration membrane used in following example is 1000；The organic solvent used is the turpentine derivatives of natural origin, and wherein, turpentine derivatives is the isomery of pinene, disproportionation products；The microbe leaven used is 2: 1: 2 mixing gained in mass ratio by lactobacillus, Bacillus licheniformis, Corynebacterium glutamicum.
Embodiment 1
S1, the aqueous solution of Flos Lonicerae extract is first passed through composite polrvinyl chloride ultrafilter membrane and carries out membrance separation, collect permeate, after by the NF membrane of molecular cut off 250 extracting solution is concentrated into the 11% of original volume again, macroporous resin column is passed through with the flow velocity of 2BV/h, dynamic adsorption is saturated, first colourless to effluent with the above-mentioned macroporous resin column of flow velocity drip washing of 3BV/h with deionized water, eluting is carried out with the flow velocity of 7BV/h again with the organic solvent that volume fraction is 30%, collect organic solvent eluent until flowing out without chlorogenic acid, finally will collect gained eluent concentrating under reduced pressure, obtain extractum；Polyamide column is passed through with the flow velocity of 1BV/h by after extractum water dissolution, after dynamic adsorption is saturated, with the 3BV deionized water above-mentioned polyamide column of flow velocity drip washing with 1BV/h, eluting is carried out with the flow velocity of 5BV/h again with the aqueous solutions of organic solvent that volume fraction is 20%, collect organic solvent eluent until flowing out without chlorogenic acid, spray drying, obtains chlorogenic acid；
S2, take 60 portions of Nostoc, clean, wear into coarse powder with grinder, then with 85 DEG C of hot-water soak 85min, pull out after draining, add 15 parts of room temperature pure water, and even, then according to the ratio microbe inoculation leaven of inoculum concentration 1.5%, keep temperature 35 DEG C, ferment 48 hours, oven drying at low temperature after fermentation ends, grind to form fine powder, obtain Nostoc yeast powder；
S3, weigh Cortex Cinnamomi peel of stem 10 parts, after Milk Thistle 10 parts, Stigma Maydis 10 parts, cranberry 3 parts, Folium Ginkgo 3 parts, 10 parts of Folium olive flash extracter process, gained extracting solution first heats with high heat, heats 1h with slow fire after boiling, and hollow fiber ultrafiltration membrane filters；Medicinal residues add 15 times of soak by water twice, and hollow fiber ultrafiltration membrane filters, and merges three filtrates, is concentrated into 1.5g/ml；It is slowly added to 90% organic solvent, until organic solvent concentration is 55%, cold preservation 8 hours, remove supernatant after the centrifugal 15min of 2000r/min, precipitate with deionized water is dissolved to original volume, with organic solvent deposit 2 times, organic solvent concentration respectively 65%, 75%；Precipitate with deionized water is dissolved to original volume, adds the solution of trichloroacetic acid that mass fraction is 10% of original volume 1/6 volume, goes to precipitate to obtain supernatant, by gained supernatant sucking filtration, dry, obtain extract after fully standing the centrifugal 15min of 4h, 2000r/min after mixing；
S4, weigh celery seed elite 3 parts, propolis 4 parts, the chlorogenic acid 10 parts of step S1 gained, step S2 gained Nostoc yeast powder 15 parts be placed in homogenizer, add step S3 gained extract stirring 5min, obtain pharmaceutical composition.
Embodiment 2
S1, the aqueous solution of Flos Lonicerae extract is first passed through composite polrvinyl chloride ultrafilter membrane and carries out membrance separation, collect permeate, after by the NF membrane of molecular cut off 250 extracting solution is concentrated into the 11% of original volume again, macroporous resin column is passed through with the flow velocity of 6BV/h, dynamic adsorption is saturated, first colourless to effluent with the above-mentioned macroporous resin column of flow velocity drip washing of 11BV/h with deionized water, eluting is carried out with the flow velocity of 13BV/h again with the organic solvent that volume fraction is 110%, collect organic solvent eluent until flowing out without chlorogenic acid, finally will collect gained eluent concentrating under reduced pressure, obtain extractum；Polyamide column is passed through with the flow velocity of 5BV/h by after extractum water dissolution, after dynamic adsorption is saturated, with the 8BV deionized water above-mentioned polyamide column of flow velocity drip washing with 10BV/h, eluting is carried out with the flow velocity of 10BV/h again with the aqueous solutions of organic solvent that volume fraction is 100%, collect organic solvent eluent until flowing out without chlorogenic acid, spray drying, obtains chlorogenic acid；
S2, take 70 portions of Nostoc, clean, wear into coarse powder with grinder, then with 90 DEG C of hot-water soak 85min, pull out after draining, add 25 parts of room temperature pure water, and even, then according to the ratio microbe inoculation leaven of inoculum concentration 1.5%, keep temperature 41 DEG C, ferment 48 hours, oven drying at low temperature after fermentation ends, grind to form fine powder, obtain Nostoc yeast powder；
S3, weigh Cortex Cinnamomi peel of stem 15 parts, Milk Thistle 15 parts, Stigma Maydis 15 parts, cranberry 10 parts, Folium Ginkgo 10 parts, 15 parts of Folium olive flash extracter process after, gained extracting solution first heats with high heat, heating 1.5h with slow fire after boiling, hollow fiber ultrafiltration membrane filters；Medicinal residues add 25 times of soak by water twice, and hollow fiber ultrafiltration membrane filters, and merges three filtrates, is concentrated into 1.5g/ml；It is slowly added to 100% organic solvent, until organic solvent concentration is 65%, cold preservation 9 hours, remove supernatant after the centrifugal 25min of 4000r/min, precipitate with deionized water is dissolved to original volume, with organic solvent deposit 2 times, organic solvent concentration respectively 75%, 85%；Precipitate with deionized water is dissolved to original volume, adds the solution of trichloroacetic acid that mass fraction is 12% of original volume 1/5 volume, goes to precipitate to obtain supernatant, by gained supernatant sucking filtration, dry, obtain extract after fully standing the centrifugal 25min of 6h, 4000r/min after mixing；
S4, weigh celery seed elite 6 parts, propolis 6 parts, the chlorogenic acid 15 parts of step S1 gained, step S2 gained Nostoc yeast powder 20 parts be placed in homogenizer, add step S3 gained extract stirring 30min, obtain pharmaceutical composition.
Embodiment 3
S1, the aqueous solution of Flos Lonicerae extract is first passed through composite polrvinyl chloride ultrafilter membrane and carries out membrance separation, collect permeate, after by the NF membrane of molecular cut off 250 extracting solution is concentrated into the 11% of original volume again, macroporous resin column is passed through with the flow velocity of 4BV/h, dynamic adsorption is saturated, first colourless to effluent with the above-mentioned macroporous resin column of flow velocity drip washing of 7BV/h with deionized water, eluting is carried out with the flow velocity of 10BV/h again with the organic solvent that volume fraction is 65%, collect organic solvent eluent until flowing out without chlorogenic acid, finally will collect gained eluent concentrating under reduced pressure, obtain extractum；Polyamide column is passed through with the flow velocity of 3BV/h by after extractum water dissolution, after dynamic adsorption is saturated, with the 5.5BV deionized water above-mentioned polyamide column of flow velocity drip washing with 5.5BV/h, eluting is carried out with the flow velocity of 7.5BV/h again with the aqueous solutions of organic solvent that volume fraction is 60%, collect organic solvent eluent until flowing out without chlorogenic acid, spray drying, obtains chlorogenic acid；
S2, take 65 portions of Nostoc, clean, wear into coarse powder with grinder, then with 87.5 DEG C of hot-water soak 85min, pull out after draining, add 20 parts of room temperature pure water, and even, then according to the ratio microbe inoculation leaven of inoculum concentration 1.5%, keep temperature 38 DEG C, ferment 48 hours, oven drying at low temperature after fermentation ends, grind to form fine powder, obtain Nostoc yeast powder；
S3, weigh Cortex Cinnamomi peel of stem 12.5 parts, Milk Thistle 12.5 parts, Stigma Maydis 12.5 parts, cranberry 6.5 parts, Folium Ginkgo 6.5 parts, 12.5 parts of Folium olive flash extracter process after, gained extracting solution first heats with high heat, heating 1.25h with slow fire after boiling, hollow fiber ultrafiltration membrane filters；Medicinal residues add 20 times of soak by water twice, and hollow fiber ultrafiltration membrane filters, and merges three filtrates, is concentrated into 1.5g/ml；It is slowly added to 95% organic solvent, until organic solvent concentration is 60%, cold preservation 8.5 hours, supernatant is removed after the centrifugal 20min of 3000r/min, precipitate with deionized water is dissolved to original volume, with organic solvent deposit 2 times, and organic solvent concentration respectively 70%, 80%；Precipitate with deionized water is dissolved to original volume, adds the solution of trichloroacetic acid that mass fraction is 11% of original volume 11/60 volume, goes to precipitate to obtain supernatant, by gained supernatant sucking filtration, dry, obtain extract after fully standing the centrifugal 20min of 5h, 3000r/min after mixing；
S4, weigh celery seed elite 4.5 parts, propolis 5 parts, the chlorogenic acid 12.5 parts of step S1 gained, step S2 gained Nostoc yeast powder 17.5 parts be placed in homogenizer, add step S3 gained extract stirring 17.5min, obtain pharmaceutical composition.
The above is only the preferred embodiment of the present invention; it should be pointed out that, for those skilled in the art, under the premise without departing from the principles of the invention; can also making some improvements and modifications, these improvements and modifications also should be regarded as protection scope of the present invention.
Claims (7)
1. the compositions nursing one's health blood fat and blood pressure, it is characterised in that be prepared from by the raw material of following weight portion:
Flos Lonicerae extract chlorogenic acid 10～15 parts, Nostoc yeast powder 15～20 parts, Cortex Cinnamomi peel of stem 10～15 parts, celery seed elite 3～6 parts, Milk Thistle 10～15 parts, Stigma Maydis 10～15 parts, cranberry 3～10 parts, Folium Ginkgo 3～10 parts, 10～15 parts of Folium olive, propolis 4～6 parts.
2. the preparation method of the compositions nursing one's health blood fat and blood pressure, it is characterised in that comprise the steps:
S1, the aqueous solution of Flos Lonicerae extract is first passed through composite polrvinyl chloride ultrafilter membrane and carries out membrance separation, collect permeate, after by the NF membrane of molecular cut off 250 extracting solution is concentrated into the 11% of original volume again, macroporous resin column is passed through with the flow velocity of 2～6BV/h, dynamic adsorption is saturated, first colourless to effluent with the above-mentioned macroporous resin column of flow velocity drip washing of 3～11BV/h with deionized water, eluting is carried out with the flow velocity of 7～13BV/h again with the organic solvent that volume fraction is 30%～110%, collect organic solvent eluent until flowing out without chlorogenic acid, finally will collect gained eluent concentrating under reduced pressure, obtain extractum；Polyamide column is passed through with the flow velocity of 1～5BV/h by after extractum water dissolution, after dynamic adsorption is saturated, with 3～8BV deionized water above-mentioned polyamide column of flow velocity drip washing with 1～10BV/h, eluting is carried out with the flow velocity of 5～10BV/h again with the aqueous solutions of organic solvent that volume fraction is 20%～100%, collect organic solvent eluent until flowing out without chlorogenic acid, spray drying, obtains chlorogenic acid；
S2, take 60～70 portions of Nostoc, clean, wear into coarse powder with grinder, then with 85～90 DEG C of hot-water soak 85min, pull out after draining, add 15～25 parts of room temperature pure water, and even, then according to the ratio microbe inoculation leaven of inoculum concentration 1.5%, keep temperature 35～41 DEG C, ferment 48 hours, oven drying at low temperature after fermentation ends, grind to form fine powder, obtain Nostoc yeast powder；
S3, weigh Cortex Cinnamomi peel of stem 10～15 parts, Milk Thistle 10～15 parts, Stigma Maydis 10～15 parts, cranberry 3～10 parts, Folium Ginkgo 3～10 parts, 10～15 parts of Folium olive flash extracter process after, gained extracting solution first heats with high heat, heating 1～1.5h with slow fire after boiling, hollow fiber ultrafiltration membrane filters；Medicinal residues add 15～25 times of soak by water twice, and hollow fiber ultrafiltration membrane filters, and merges three filtrates, is concentrated into 1.5g/ml；It is slowly added to 90～100% organic solvents, until organic solvent concentration is 55～65%, cold preservation 8～9 hours, supernatant is removed after the centrifugal 15～25min of 2000～4000r/min, precipitate with deionized water is dissolved to original volume, with organic solvent deposit 2 times, organic solvent concentration respectively 65～75%, 75～85%；Precipitate with deionized water is dissolved to original volume, adds the solution of trichloroacetic acid that mass fraction is 10～12% of original volume 1/6～1/5 volume, fully stands 4～6h after mixing, go to precipitate to obtain supernatant after the centrifugal 15～25min of 2000～4000r/min, by gained supernatant sucking filtration, dry, obtain extract；
S4, weigh celery seed elite 3～6 parts, propolis 4～6 parts, the chlorogenic acid 10～15 parts of step S1 gained, step S2 gained Nostoc yeast powder 15～20 parts be placed in homogenizer, add the extract stirring 5～30min of step S3 gained, obtain pharmaceutical composition.
3. the preparation method of a kind of compositions nursing one's health blood fat and blood pressure according to claim 2, it is characterised in that the molecular cut off of described hollow fiber ultrafiltration membrane is 1000.
4. the preparation method of a kind of compositions nursing one's health blood fat and blood pressure according to claim 2, it is characterised in that described organic solvent is the turpentine derivatives of natural origin.
5. the preparation method of a kind of compositions nursing one's health blood fat and blood pressure according to claim 2, it is characterised in that described turpentine derivatives is the isomery of pinene, disproportionation products.
6. the preparation method of a kind of compositions nursing one's health blood fat and blood pressure according to claim 2, it is characterised in that described microbe leaven is by lactobacillus, Bacillus licheniformis, Corynebacterium glutamicum mixing gained.
7. the preparation method of a kind of compositions nursing one's health blood fat and blood pressure according to claim 2, it is characterised in that lactobacillus in described microbe leaven, Bacillus licheniformis, Corynebacterium glutamicum mass ratio be 2: 1: 2.
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| CN112869089A (en) * | 2021-01-28 | 2021-06-01 | 海口橄爱餐饮管理有限公司 | Cassava tender shoot olive dish and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106334044A (en) * | 2016-08-16 | 2017-01-18 | 西安市第医院 | Medicament capable of improving central nervous system inflammation |
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| CN112869089A (en) * | 2021-01-28 | 2021-06-01 | 海口橄爱餐饮管理有限公司 | Cassava tender shoot olive dish and preparation method thereof |
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