CN105640831A - Multi-effect plant cleanser - Google Patents
Multi-effect plant cleanser Download PDFInfo
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- CN105640831A CN105640831A CN201610031191.7A CN201610031191A CN105640831A CN 105640831 A CN105640831 A CN 105640831A CN 201610031191 A CN201610031191 A CN 201610031191A CN 105640831 A CN105640831 A CN 105640831A
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- facial milk
- extract
- milk cleanser
- many effects
- tetrandrine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
Abstract
The invention relates to the field of cosmetics, in particular to multi-effect plant cleanser. The multi-effect plant cleanser is mainly prepared from ginkgo biloba extracts, tetrandrine extracts and second components. The second components are oat extracts or willow bark extracts. The multi-effect plant cleanser is prepared from, by weight, 2-6 parts of ginkgo biloba extracts, 1-3 parts of tetrandrine extracts and 2-6 parts of the second components. Through many times of experiments, it is found that the multi-effect plant cleanser is prepared from specific ginkgo biloba extracts, tetrandrine extracts and oat extracts or willow bark extracts, the components are used in cooperation, deep-layer dirt gathered in pores can be effectively decomposed, the effects of removing comedo and closed comedo, shrinking pores, softening and awakening skin, adjusting sebum, diminishing inflammation and relieving acne, enhancing skin immunity and the like are achieved, the skin is made soft, smooth, tender, white and clear, and use is safe.
Description
Technical field
The present invention relates to cosmetic field, in particular to a kind of many effects plant facial milk cleanser.
Background technology
Raising along with living standards of the people and the demand to own health, various cosmetics increasingly come into one's own. Owing to active components of plants has that effect is good, side effect is little and without allergic phenomena, there is superiority more more than synthesis cosmetics, so be increasingly subject to the favor of consumers in general based on the daily chemical products of improving looks of pure natural plant composition. Advocating the development trend that green, back to nature have been cosmetic industry, the cosmetics therefore researching and developing plant resources become an indispensable link of cosmetic industry sustainable development.
Blackhead, small pox, corse sweat pore etc. become the puzzlement of people, market has also been emerged in large numbers a lot of product for these symptoms, but effect is still not good.
In view of this, the special proposition present invention.
Summary of the invention
It is an object of the invention to provide a kind of many effects plant facial milk cleanser, described many effects plant facial milk cleanser, there is extraordinary removing blackhead, pore refining and antiinflammatory and stop the effect of pox, make the soft and smooth delicacy of skin, pale clear, use safety.
In order to realize the above-mentioned purpose of the present invention, spy by the following technical solutions:
A kind of many effects plant facial milk cleanser, is mainly made up of Semen Ginkgo extrac, tetrandrine extract and second component, and described second component is oat extract or extract of willow bark;
By weight, Semen Ginkgo extrac 2-6 part, tetrandrine extract 1-3 part, second component 2-6 part.
Many effects plant facial milk cleanser provided by the invention, through test of many times discovery, specific selection Semen Ginkgo extrac, tetrandrine extract and oat extract or extract of willow bark, cooperate between each composition, can effectively decompose the deep layer dirt being collected in pore, remove blackhead, hoary hair, pore refining, soft skin is waken up skin, regulates sebum, and antiinflammatory stops pox, strengthen the effects such as skin immunization power, make the soft and smooth delicacy of skin, pale clear, use safety.
Finding through test, it is more notable with the effect reducing pore that second component selects oat extract to remove blackhead. Preferably, described second component is oat extract, and described many effects plant facial milk cleanser is mainly made up of Semen Ginkgo extrac 1.5-2.5 weight portion, tetrandrine extract 1.5-2.5 weight portion and oat extract 4-6 weight portion.
Finding through test, second component selects extract of willow bark whitening effect more notable. Preferably, described second component is extract of willow bark, and described many effects plant facial milk cleanser is mainly made up of Semen Ginkgo extrac 1.5-2.5 weight portion, tetrandrine extract 2.5-3.5 weight portion and extract of willow bark 4-6 weight portion.
Further, described tetrandrine extract is prepared by following steps:
A (), Radix Stephaniae Tetrandrae powder are first soaked in water 25-40min, the weight ratio of water and Radix Stephaniae Tetrandrae powder is 1-1.5:1, is subsequently adding the ethanol that volumetric concentration is 78%-85%, and making the volumetric concentration of ethanol in solvent is 18%-25%;
(b), in 52-56 DEG C of reflux, extract, filter, respectively obtain filtering residue and the first filtrate;
(c), in described filtering residue, add water, be 3.6-4.0 with Fructus Citri Limoniae acid for adjusting pH value, add cellulase, in 52-56 DEG C of reflux, extract, filter, obtain the second filtrate;
(d), described first filtrate is mixed with described second filtrate, spray drying obtains described tetrandrine extract.
The preparation method of tetrandrine extract provided by the invention, Radix Stephaniae Tetrandrae powder first soaks with water, is subsequently adding ethanol and extracts, and makes the sufficient dissolution of effective active composition in Radix Stephaniae Tetrandrae powder; And the filtering residue after extracting still contains more effective active composition, the present invention adopts cellulase that it is carried out enzymolysis, then extracts again so that the effective active composition in Radix Stephaniae Tetrandrae powder such as tetrandrine, monosaccharide and oligosaccharide etc. are extracted; Spray drying after filtrate merging, obtains pulverous tetrandrine extract. Without the participation of harmfulness organic reagent in whole preparation process, reducing the pollution to environment in extraction process, prepared tetrandrine extract is safer. The tetrandrine extract pure natural prepared, non-stimulated, no cytotoxicity, effective active composition therein is mainly tetrandrine, and all the other are then oligosaccharide, monosaccharide, hanfangchin B, several biological alkali etc., has natural antiallergic anti-inflammatory anti-itch effect of brilliance.
Preferably, in step (b) and/or step (c), described in be filtered into: be first filtered with plate-and-frame filtration equipment, the filtrate obtained then at more than 8000r/min be centrifuged.
Preferably, the filtrate obtained is centrifuged then at 10000r/min-15000r/min.
As: in certain embodiments, centrifugal speed can be 10000r/min; In certain embodiments, centrifugal speed can be 11000r/min; In certain embodiments, centrifugal speed can be 12000r/min; In certain embodiments, centrifugal speed can be 13000r/min; In certain embodiments, centrifugal speed can be 15000r/min; In certain embodiments, centrifugal speed can be 15000r/min; Etc..
As in step (b), extracting mixed liquor and be first filtered with plate-and-frame filtration equipment, obtain filtrate and filtering residue, then filtrate carries out high speed centrifugation, and it is then whole filtering residue that the centrifugal supernatant obtained is the first filtrate, centrifugation and filtering residue;
In step (c), extracting mixed liquor and be first filtered with plate-and-frame filtration equipment, obtain filtrate and filtering residue, then filtrate carries out high speed centrifugation, and the centrifugal supernatant obtained is the second filtrate.
Being filtered by which, the first filtrate obtained and the effective active component damages of the second filtrate are few, and composition is pure.
Preferably, in step (c), the addition of described cellulase is the 0.5%-1% of filtering residue weight.
Filtering residue still contains more effective active composition, the present invention adds water and is disperseed by filtering residue, it is subsequently adding appropriate cellulase filtering residue is decomposed, then passes through extraction and make effective active composition be fully dissolved out, obtain the second filtrate containing effective active composition.
Preferably, described many effects plant face cleaning composition of milk also includes adjuvant;
Described many effects plant facial milk cleanser is divided into skin moistening type, anti-ageing type and light;
Described many effects plant facial milk cleanser is skin moistening type facial milk cleanser, described adjuvant includes following component: by weight, glycerol 5.5-6.5 part, sodium lauryl sulfate 0.4-0.6 part, cocos nucifera oil acyl glucoside 1.5-2.5 part, sodium methyl cocoyl taurate 2.5-3.5 part, cetearyl alcohol 7.5-8.5 part, Dormant oils 4.5-5.5 part, glyceryl stearate 2.5-3.5 part, phenoxyethanol 0.4-0.6 part;
Described many effects plant facial milk cleanser is anti-ageing type facial milk cleanser, and described adjuvant includes following component: by weight, sodium lauroyl sarcosine 2.5-3.5 part, stearic acid 15-17 part, glycerol 5-7 part, myristic acid 7-9 part, propylene glycol 3-5 part, lauric acid 2.5-3.5 part, potassium hydroxide 5-5.5 part, sodium methyl cocoyl taurate 3.5-4.5 part, cocamido propyl betaine 2.5-3.5 part, phenoxyethanol 0.4-0.6 part, essence 0.04-0.06 part;
Described many effects plant facial milk cleanser is light facial milk cleanser, described adjuvant includes following component: by weight, lauryl alcohol sulfosuccinate disodium 38-42 part, sodium lauroyl sarcosine 9-11 part, coconut oleoyl amine MEA0.8-1.2 part, glycerol 1-3 part, sodium chloride 1-3 part, PEG-120 methyl dioleate 0.8-1.2 part, sodium methyl cocoyl taurate 1.5-2.5 part, cocamido propyl betaine 2.5-3.5 part, phenoxyethanol 0.4-0.6 part, essence 0.04-0.06 part;
Wherein, described many effects plant facial milk cleanser is 100 weight portions, and surplus is used that deionized water is supplied.
Through multiple authentication, adopting the adjuvant of above proportioning to make different types of facial milk cleanser, use skin safe, each index meets the requirement of cosmetics; It addition, make different types of facial milk cleanser, better meet the diversified demand of masses.
Preferably, described many effects plant facial milk cleanser is skin moistening type facial milk cleanser, and described many effects plant facial milk cleanser is prepared by the following method:
Extract of willow bark, glycerol, sodium lauryl sulfate, cocos nucifera oil acyl glucoside, sodium methyl cocoyl taurate and deionized water are mixed, is heated to 85 �� 2 DEG C, be incubated 28-35min, obtain A phase;
By cetearyl alcohol, Dormant oils, glyceryl stearate mixing, it is heated to 85 �� 2 DEG C, is incubated 28-35min, obtains B phase;
When stirring, B is added in A phase, stirs 4-6min, then vacuum homogenizing;
Being cooled to 43-45 DEG C after homogenizing, add Semen Ginkgo extrac, tetrandrine extract and phenoxyethanol, evacuation stirring 8-12min, less than 38 DEG C stoppings are stirred.
This skin moistening type facial milk cleanser is suitable for middle dryness or thick dark Huang skin, has anti-inflammation, deep layer cleaning, moist whitening, replenishing water and preserving moisture, adjustment sebum, keeps skin ph to balance, make the soft and moist brilliant white of skin.
Preferably, described many effects plant facial milk cleanser is anti-ageing type facial milk cleanser, and described many effects plant facial milk cleanser is prepared by the following method:
Sodium lauroyl sarcosine, stearic acid, glycerol, myristic acid, propylene glycol, lauric acid and deionized water are mixed, is heated to 80 �� 2 DEG C, be incubated 18-25min, obtain A phase;
Potassium hydroxide and water are mixed, obtains B phase;
Under stirring, B is added to A phase, stirs 8-15min, homogenizing 3-5min, be incubated 18-25min;
Add sodium methyl cocoyl taurate and cocamido propyl betaine, stirring insulation 18-25min, when being cooled to 40 �� 2 DEG C, add oat extract, Semen Ginkgo extrac, tetrandrine extract and essence, mix homogeneously, place 20-25h.
Preferably, described many effects plant facial milk cleanser is light facial milk cleanser, and described many effects plant facial milk cleanser is prepared by the following method:
Deionized water is mixed with sodium chloride, it is subsequently adding lauryl alcohol sulfosuccinate disodium, sodium lauroyl sarcosine, coconut oleoyl amine MEA, glycerol, PEG-120 methyl dioleate, sodium methyl cocoyl taurate, cocamido propyl betaine, it is stirred and heated to 85 �� 2 DEG C, insulation 28-35min, obtains A phase;
When A phase is cooled to 45 �� 2 DEG C, adds Semen Ginkgo extrac, tetrandrine extract and oat extract, stir;
When temperature is down to 40 �� 2 DEG C, add phenoxyethanol and essence, mix homogeneously, stop when temperature is 35 DEG C stirring.
The anti-ageing type facial milk cleanser and the light facial milk cleanser that prepare are suitable for any skin, plant essence coordinates with the high activity factor, effectively decomposite the deep layer dirt being collected in pore, remove blackhead, hoary hair, pore refining, soft skin wake up skin, regulate sebum, antiinflammatory and stop pox, strengthen skin immunization power, make the soft and smooth delicacy of skin, pale clear.
The skin moistening type, anti-ageing type and each component distributing of light facial milk cleanser that are prepared by said method are homogeneous, and the damage of effective active composition is little, during use, skin effect is soft.
Compared with prior art, the invention have the benefit that
(1) many effects plant facial milk cleanser provided by the invention, through test of many times discovery, the Semen Ginkgo extrac of specific selection special ratios, tetrandrine extract and oat extract or extract of willow bark, cooperate between each composition, can effectively decompose the deep layer dirt being collected in pore, gentle removal blackhead, hoary hair, pore refining, soft skin is waken up skin, regulates sebum metabolism, and antiinflammatory stops pox, strengthen the effects such as skin immunization power, make the soft and smooth delicacy of skin, pale clear, use safety.
(2) present invention also offers specific tetrandrine method for preparing extractive, the tetrandrine extract pure natural prepared, non-stimulated, no cytotoxicity, effective active composition therein is mainly tetrandrine, all the other are then oligosaccharide, monosaccharide, hanfangchin B, several biological alkali etc., have natural antiallergic anti-inflammatory anti-itch effect of brilliance.
(3) present invention also offers different types of facial milk cleanser, the prepared each component distributing of different types of facial milk cleanser is homogeneous, and the damage of effective active composition is little, during use, skin effect is soft, uses safety, better meets the demand of masses.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, it will be appreciated by those skilled in the art that the following example is merely to illustrate the present invention, and are not construed as restriction the scope of the present invention. Unreceipted actual conditions person in embodiment, conventionally the condition of condition or manufacturer's suggestion carries out. Agents useful for same or the unreceipted production firm person of instrument, being can by the conventional products of commercially available acquisition.
Embodiment 1
Preparing tetrandrine extract, its step is as follows:
Group 1: take 100g Radix Stephaniae Tetrandrae powder, add distilled water 100g, soaks 25min, is subsequently adding the ethanol water that volumetric concentration is 80% after mixing, making the volumetric concentration of ethanol in solvent is 18%;
In 52 DEG C of reflux, extract, 65min, extracting mixed liquor and be first filtered with plate-and-frame filtration equipment, obtain filtering residue and filtrate, the filtrate obtained is in 8000r/min, and the centrifugal supernatant obtained is the first filtrate, and the centrifugal precipitation obtained retains;
Water is added after the centrifugal precipitation obtained and filtering residue mixing, amount of water is 5 times of precipitation and filtering residue weight, it is 3.6 with Fructus Citri Limoniae acid for adjusting pH value, add cellulase, the addition of cellulase is the 0.5% of the centrifugal precipitation obtained and filtering residue gross weight, then at 52 DEG C of reflux, extract, 65min, extracts mixed liquor and is first filtered with plate-and-frame filtration equipment, the filtrate obtained is centrifuged in 8000r/min, and the centrifugal supernatant obtained is the second filtrate;
First filtrate being mixed with the second filtrate, spray drying obtains tetrandrine extract;
After testing, containing tetrandrine 0.84g in this tetrandrine extract, the yield of tetrandrine is 0.84%; Additionally possibly together with hanfangchin B 0.5g, micromolecular polysaccharide 2g, small-molecular peptides 0.5g, inorganic salt 0.8g.
Group 2: take the Radix Stephaniae Tetrandrae powder that 100g granularity is 50 orders, add distilled water 150g, soaks 40min, is subsequently adding the ethanol water that volumetric concentration is 85% after mixing, making the volumetric concentration of ethanol in solvent is 20%;
In 55 DEG C of reflux, extract, 60min, extracting mixed liquor and be first filtered with plate-and-frame filtration equipment, obtain filtering residue and filtrate, the filtrate obtained is centrifuged in 10000r/min, and the centrifugal supernatant obtained is the first filtrate, and the centrifugal precipitation obtained retains;
Water is added after the centrifugal precipitation obtained and filtering residue mixing, amount of water is 4.5 times of precipitation and filtering residue weight, it is 3.7 with Fructus Citri Limoniae acid for adjusting pH value, add cellulase, the addition of cellulase is the 1% of the centrifugal precipitation obtained and filtering residue gross weight, then at 55 DEG C of reflux, extract, 60min, extracts mixed liquor and is first filtered with plate-and-frame filtration equipment, the filtrate obtained is centrifuged in 10000r/min, and the centrifugal supernatant obtained is the second filtrate;
First filtrate being mixed with the second filtrate, spray drying obtains tetrandrine extract;
After testing, containing tetrandrine 0.85g in this tetrandrine extract, the yield of tetrandrine is 0.85%; Additionally possibly together with hanfangchin B 0.52g, micromolecular polysaccharide 2.3g, small-molecular peptides 0.55g, inorganic salt 0.8g.
Group 3: take the Radix Stephaniae Tetrandrae powder that 100g granularity is 100 orders, add distilled water 100g, soaks 30min, is subsequently adding the ethanol water that volumetric concentration is 78% after mixing, making the volumetric concentration of ethanol in solvent is 25%;
In 56 DEG C of reflux, extract, 55min, extracting mixed liquor and be first filtered with plate-and-frame filtration equipment, obtain filtering residue and filtrate, the filtrate obtained is centrifuged in 15000r/min, and the centrifugal supernatant obtained is the first filtrate, and the centrifugal precipitation obtained retains;
Water is added after the centrifugal precipitation obtained and filtering residue mixing, amount of water is 4 times of precipitation and filtering residue weight, it is 4.0 with Fructus Citri Limoniae acid for adjusting pH value, add cellulase, the addition of cellulase is the 0.8% of the centrifugal precipitation obtained and filtering residue gross weight, then at 56 DEG C of reflux, extract, 55min, extracts mixed liquor and is first filtered with plate-and-frame filtration equipment, the filtrate obtained is centrifuged in 15000r/min, and the centrifugal supernatant obtained is the second filtrate;
First filtrate being mixed with the second filtrate, spray drying obtains tetrandrine extract;
After testing, containing tetrandrine 0.84g in this tetrandrine extract, the yield of tetrandrine is 0.84%;Additionally possibly together with hanfangchin B 0.53g, micromolecular polysaccharide 2.5g, small-molecular peptides 0.7g, inorganic salt 0.9g.
Group 4: take the Radix Stephaniae Tetrandrae powder that 100g granularity is 150 orders, add distilled water 100g, soaks 30min, is subsequently adding the ethanol water that volumetric concentration is 80% after mixing, making the volumetric concentration of ethanol in solvent is 20%;
In 55 DEG C of reflux, extract, 60min, extracting mixed liquor and be first filtered with plate-and-frame filtration equipment, obtain filtering residue and filtrate, the filtrate obtained is centrifuged in 12000r/min, and the centrifugal supernatant obtained is the first filtrate, and the centrifugal precipitation obtained retains;
Water is added after the centrifugal precipitation obtained and filtering residue mixing, amount of water is 5 times of precipitation and filtering residue weight, it is 3.7 with Fructus Citri Limoniae acid for adjusting pH value, add cellulase, the addition of cellulase is the 1% of the centrifugal precipitation obtained and filtering residue gross weight, then at 55 DEG C of reflux, extract, 60min, extracts mixed liquor and is first filtered with plate-and-frame filtration equipment, the filtrate obtained is centrifuged in 12000r/min, and the centrifugal supernatant obtained is the second filtrate;
First filtrate being mixed with the second filtrate, spray drying obtains tetrandrine extract;
After testing, containing tetrandrine 0.86g in this tetrandrine extract, the yield of tetrandrine is 0.86%; Additionally possibly together with hanfangchin B 0.6g, micromolecular polysaccharide 2.4g, small-molecular peptides 0.53g, inorganic salt 0.85g.
Embodiment 2
The proportioning of each raw material of table 1 skin moistening type facial milk cleanser
Skin moistening type facial milk cleanser is prepared by the following method:
Extract of willow bark, glycerol, sodium lauryl sulfate, cocos nucifera oil acyl glucoside, sodium methyl cocoyl taurate and deionized water are mixed, is heated to 85 �� 2 DEG C, be incubated 28-35min, obtain A phase;
By cetearyl alcohol, Dormant oils, glyceryl stearate mixing, it is heated to 85 �� 2 DEG C, is incubated 28-35min, obtains B phase;
When stirring, B is added in A phase, stirs 4-6min, then vacuum homogenizing;
It is cooled to 43-45 DEG C after homogenizing, adds Semen Ginkgo extrac, tetrandrine extract and phenoxyethanol, evacuation stirring 8-12min, less than 38 DEG C stoppings are stirred;
Wherein each raw material is pressed the weight portion in table 1 and is added, and tetrandrine extract adopts group 3 in embodiment 1 to prepare.
In step prepared by skin moistening type facial milk cleanser, the demand according to raw material, the scope in the optional step of each step is operated.
Embodiment 3
The proportioning of each raw material of table 2 anti-ageing type facial milk cleanser
Anti-ageing type facial milk cleanser is prepared by the following method:
Sodium lauroyl sarcosine, stearic acid, glycerol, myristic acid, propylene glycol, lauric acid and deionized water are mixed, is heated to 80 �� 2 DEG C, be incubated 18-25min, obtain A phase;
Potassium hydroxide and water are mixed, obtains B phase;
Under stirring, B is added to A phase, stirs 8-15min, homogenizing 3-5min, be incubated 18-25min;
Add sodium methyl cocoyl taurate and cocamido propyl betaine, stirring insulation 18-25min, when being cooled to 40 �� 2 DEG C, add oat extract, Semen Ginkgo extrac, tetrandrine extract and essence, mix homogeneously, place 20-25h;
Wherein each raw material is pressed the weight portion in table 2 and is added, and tetrandrine extract adopts group 3 in embodiment 1 to prepare.
In step prepared by anti-ageing type facial milk cleanser, the demand according to raw material, the scope in the optional step of each step is operated.
Embodiment 4
The proportioning of each raw material of the light facial milk cleanser of table 3
Light facial milk cleanser is prepared by the following method:
Deionized water is mixed with sodium chloride, it is subsequently adding lauryl alcohol sulfosuccinate disodium, sodium lauroyl sarcosine, coconut oleoyl amine MEA, glycerol, PEG-120 methyl dioleate, sodium methyl cocoyl taurate, cocamido propyl betaine, it is stirred and heated to 85 �� 2 DEG C, insulation 28-35min, obtains A phase;
When A phase is cooled to 45 �� 2 DEG C, adds Semen Ginkgo extrac, tetrandrine extract and oat extract, stir;
When temperature is down to 40 �� 2 DEG C, add phenoxyethanol and essence, mix homogeneously, stop when temperature is 35 DEG C stirring.
Wherein each raw material is pressed the weight portion of table 3 and is added, and tetrandrine extract adopts group 3 in embodiment 1 to prepare.
In step prepared by light facial milk cleanser, the demand according to raw material, the scope in the optional step of each step is operated.
The different types of facial milk cleanser that embodiment 2-4 prepares detects according to the regulation of cosmetics, all meets the requirement of cosmetics.
Test example 1
The different types of facial milk cleanser that embodiment 2-4 difference group prepares is tested, specific as follows: to select the adolescence having the 20-30 year of small pox or pox speckle on 1300 faces, it is divided into 13 groups, test group 1-9 and matched group 1 and matched group 2, wherein test group 1-9 uses the facial milk cleanser that embodiment prepares respectively, and matched group 1 uses Li doctor's anti-acne facial milk cleanser; Matched group 2, for the tetrandrine extract in the group 1 in embodiment 2-4 replaces with the tetrandrine of isodose, the constant facial milk cleanser made of all the other conditions, obtains the facial milk cleanser of group 1-group 3 successively. Each group is the use that sooner or later washes one's face, and after washing one's face, normal other skin-protection products of use, use 2 months. Wherein, change of skin effect standard:
Effective: small pox clearly reduces or disappears, pox scar clearly reduces or disappears;
Effective: small pox significantly reduces, pox scar significantly reduces;
Invalid: after use, skin is without improvement.
It is as shown in table 4 that its small pox or pox scar improve situation.
Table 4 small pox or pox scar improve situation
As can be seen from Table 4, many effects plant facial milk cleanser provided by the invention, acts on soft, and each active component cooperates, go deep into skin and clean dirt, antiallergic anti-inflammatory anti-itch, repairs the tissue of pore periphery, supplements the nutrients simultaneously, recover skin elasticity gradually, there is good anti-acne effect, use rear skin to become clear, use the facial milk cleanser effect that tetrandrine extract provided by the invention prepares substantially superior than tetrandrine; Further, in use having been surprisingly found that, using after two months, blackhead fades away and loses, and thick pore is fine and smooth gradually, has the effect significantly reducing pore.
Test example 2
Have for facial milk cleanser provided by the invention and remove blackhead and reduce the effect of pore, carry out tests below.
Select 1300 people have blackhead 25-40 year young people, be divided into 13 groups, test group 1-9 and matched group 1 and matched group 2, wherein test group 1-9 uses the facial milk cleanser that embodiment prepares respectively, and matched group 1 uses commercially available nose film pore cleanser to be set with; Matched group 2, for the tetrandrine extract in the group 1 in embodiment 2-4 replaces with the tetrandrine of isodose, the constant facial milk cleanser made of all the other conditions, obtains the facial milk cleanser of group 1-group 3 successively. Test group and matched group 2 are the use that sooner or later washes one's face, and after washing one's face, normal other skin-protection products of use, in use procedure, add blackhead position and rub 2min; Matched group is pressed the description of product and is used, and all uses 3 months. Wherein, change of skin effect standard:
Effective: blackhead disappears;
Effective: blackhead significantly reduces;
Invalid: after use, blackhead is without improvement.
Its blackhead situation is as shown in table 5.
Table 5 blackhead improves situation
As can be seen from Table 5, facial milk cleanser provided by the invention, there is the significant effect removing blackhead;Further, in use finding, matched group uses suit, operates more loaded down with trivial details, easily causes corse sweat pore after using; And facial milk cleanser provided by the invention uses simple, deep layer cleaning can be stretched into, remove dirt, supplement the nutrients, anti-inflammatory anti-itch, repair skin, regulate sebum metabolism, make blackhead fade away, act on soft, use the soft and smooth delicacy of rear skin, pale clear. Further, use the facial milk cleanser effect that tetrandrine extract provided by the invention prepares substantially superior than tetrandrine. Generally using 1 month namely it can be seen that significantly improve, the serious use that needs just can substantially take effect for more than two months.
Test example 3
1300 people are selected to have the young people in 25-40 year of corse sweat pore, it is divided into 13 groups, test group 1-9 and matched group 1 and matched group 2, wherein test group 1-9 uses the facial milk cleanser that embodiment prepares respectively, and matched group 1 uses the facial milk cleanser of certain commercially available deep layer cleaning corse sweat pore; Matched group 2, for the tetrandrine extract in the group 1 in embodiment 2-4 replaces with the tetrandrine of isodose, the constant facial milk cleanser made of all the other conditions, obtains the facial milk cleanser of group 1-group 3 successively. Each group is the use that sooner or later washes one's face, and after washing one's face, normal other skin-protection products of use, in use procedure, add corse sweat pore position and rub 1min, use 3 months. Wherein, change of skin effect standard:
Effective: pore disappears;
Effective: pore is obviously reduced;
Invalid: after use, pore size is without change.
It is as shown in table 6 that its pore improves situation.
Table 6 pore improves situation
As can be seen from Table 6, plant facial milk cleanser provided by the invention, there is the effect of significant pore refining; In use finding, each active component synergism of plant facial milk cleanser provided by the invention strengthens, and can effectively decompose the deep layer dirt being collected in pore, act on soft, repair the tissue of pore periphery, supplement the nutrients, packed cells, recover cell elasticity, soft skin is waken up skin, regulates sebum metabolism, pore refining, make the soft and smooth delicacy of skin, pale clear; And use the facial milk cleanser effect that tetrandrine extract provided by the invention prepares substantially superior than tetrandrine. Generally use 2 monthly have improve significantly.
It addition, tetrandrine extract used in test example 2-4 replaces with the tetrandrine extract prepared in the group 1 of embodiment 1, group 2 or group 4, the tetrandrine extract effect that result prepares with the group 3 of embodiment 1 is consistent.
In summary, many effects plant facial milk cleanser provided by the invention, find through test of many times, specific selection Semen Ginkgo extrac, tetrandrine extract and oat extract or extract of willow bark, cooperate between each composition, acts on soft, can effectively decompose the deep layer dirt being collected in pore, gentle removal blackhead, hoary hair, pore refining, soft skin is waken up skin, regulates sebum metabolism, and antiinflammatory stops pox, strengthen the effects such as skin immunization power, make the soft and smooth delicacy of skin, pale clear, use safety.
Although illustrate and describing the present invention with specific embodiment, however it will be appreciated that may be made that when without departing substantially from the spirit and scope of the present invention many other change and amendment. It is, therefore, intended that include all such changes and modifications belonging in the scope of the invention in the following claims.
Claims (10)
1. effect plant facial milk cleanser more than a kind, it is characterised in that being mainly made up of Semen Ginkgo extrac, tetrandrine extract and second component, described second component is oat extract or extract of willow bark;
By weight, Semen Ginkgo extrac 2-6 part, tetrandrine extract 1-3 part, second component 2-6 part.
2. many effects plant facial milk cleanser according to claim 1, it is characterized in that, described second component is oat extract, and described many effects plant facial milk cleanser is mainly made up of Semen Ginkgo extrac 1.5-2.5 weight portion, tetrandrine extract 1.5-2.5 weight portion and oat extract 4-6 weight portion.
3. many effects plant facial milk cleanser according to claim 1, it is characterized in that, described second component is extract of willow bark, and described many effects plant facial milk cleanser is mainly made up of Semen Ginkgo extrac 1.5-2.5 weight portion, tetrandrine extract 2.5-3.5 weight portion and extract of willow bark 4-6 weight portion.
4. many effects plant facial milk cleanser according to claim 1, it is characterised in that described tetrandrine extract is prepared by following steps:
A (), Radix Stephaniae Tetrandrae powder are first soaked in water 25-40min, the weight ratio of water and Radix Stephaniae Tetrandrae powder is 1-1.5:1, is subsequently adding the ethanol that volumetric concentration is 78%-85%, and making the volumetric concentration of ethanol in solvent is 18%-25%;
(b), in 52-56 DEG C of reflux, extract, filter, respectively obtain filtering residue and the first filtrate;
(c), in described filtering residue, add water, be 3.6-4.0 with Fructus Citri Limoniae acid for adjusting pH value, add cellulase, in 52-56 DEG C of reflux, extract, filter, obtain the second filtrate;
(d), described first filtrate is mixed with described second filtrate, spray drying obtains described tetrandrine extract.
5. many effects plant facial milk cleanser according to claim 4, it is characterized in that, in step (b) and/or step (c), described in be filtered into: be first filtered with plate-and-frame filtration equipment, the filtrate obtained then at more than 8000r/min be centrifuged.
6. many effects plant facial milk cleanser according to claim 4, it is characterised in that in step (c), the addition of described cellulase is the 0.5%-1% of filtering residue weight.
7. the many effects plant facial milk cleanser according to any one of claim 1-6, it is characterised in that described many effects plant face cleaning composition of milk also includes adjuvant;
Described many effects plant facial milk cleanser is divided into skin moistening type, anti-ageing type and light;
Described many effects plant facial milk cleanser is skin moistening type facial milk cleanser, described adjuvant includes following component: by weight, glycerol 5.5-6.5 part, sodium lauryl sulfate 0.4-0.6 part, cocos nucifera oil acyl glucoside 1.5-2.5 part, sodium methyl cocoyl taurate 2.5-3.5 part, cetearyl alcohol 7.5-8.5 part, Dormant oils 4.5-5.5 part, glyceryl stearate 2.5-3.5 part, phenoxyethanol 0.4-0.6 part;
Described many effects plant facial milk cleanser is anti-ageing type facial milk cleanser, and described adjuvant includes following component: by weight, sodium lauroyl sarcosine 2.5-3.5 part, stearic acid 15-17 part, glycerol 5-7 part, myristic acid 7-9 part, propylene glycol 3-5 part, lauric acid 2.5-3.5 part, potassium hydroxide 5-5.5 part, sodium methyl cocoyl taurate 3.5-4.5 part, cocamido propyl betaine 2.5-3.5 part, phenoxyethanol 0.4-0.6 part, essence 0.04-0.06 part;
Described many effects plant facial milk cleanser is light facial milk cleanser, described adjuvant includes following component: by weight, lauryl alcohol sulfosuccinate disodium 38-42 part, sodium lauroyl sarcosine 9-11 part, coconut oleoyl amine MEA0.8-1.2 part, glycerol 1-3 part, sodium chloride 1-3 part, PEG-120 methyl dioleate 0.8-1.2 part, sodium methyl cocoyl taurate 1.5-2.5 part, cocamido propyl betaine 2.5-3.5 part, phenoxyethanol 0.4-0.6 part, essence 0.04-0.06 part;
Wherein, described many effects plant facial milk cleanser is 100 weight portions, and surplus is used that deionized water is supplied.
8. many effects plant facial milk cleanser according to claim 7, it is characterised in that described many effects plant facial milk cleanser is skin moistening type facial milk cleanser, described many effects plant facial milk cleanser is prepared by the following method:
Extract of willow bark, glycerol, sodium lauryl sulfate, cocos nucifera oil acyl glucoside, sodium methyl cocoyl taurate and deionized water are mixed, is heated to 85 �� 2 DEG C, be incubated 28-35min, obtain A phase;
By cetearyl alcohol, Dormant oils, glyceryl stearate mixing, it is heated to 85 �� 2 DEG C, is incubated 28-35min, obtains B phase;
When stirring, B is added in A phase, stirs 4-6min, then vacuum homogenizing;
Being cooled to 43-45 DEG C after homogenizing, add Semen Ginkgo extrac, tetrandrine extract and phenoxyethanol, evacuation stirring 8-12min, less than 38 DEG C stoppings are stirred.
9. many effects plant facial milk cleanser according to claim 7, it is characterised in that described many effects plant facial milk cleanser is anti-ageing type facial milk cleanser, described many effects plant facial milk cleanser is prepared by the following method:
Sodium lauroyl sarcosine, stearic acid, glycerol, myristic acid, propylene glycol, lauric acid and deionized water are mixed, is heated to 80 �� 2 DEG C, be incubated 18-25min, obtain A phase;
Potassium hydroxide and water are mixed, obtains B phase;
Under stirring, B is added to A phase, stirs 8-15min, homogenizing 3-5min, be incubated 18-25min;
Add sodium methyl cocoyl taurate and cocamido propyl betaine, stirring insulation 18-25min, when being cooled to 40 �� 2 DEG C, add oat extract, Semen Ginkgo extrac, tetrandrine extract and essence, mix homogeneously, place 20-25h.
10. many effects plant facial milk cleanser according to claim 7, it is characterised in that described many effects plant facial milk cleanser is light facial milk cleanser, described many effects plant facial milk cleanser is prepared by the following method:
Deionized water is mixed with sodium chloride, it is subsequently adding lauryl alcohol sulfosuccinate disodium, sodium lauroyl sarcosine, coconut oleoyl amine MEA, glycerol, PEG-120 methyl dioleate, sodium methyl cocoyl taurate, cocamido propyl betaine, it is stirred and heated to 85 �� 2 DEG C, insulation 28-35min, obtains A phase;
When A phase is cooled to 45 �� 2 DEG C, adds Semen Ginkgo extrac, tetrandrine extract and oat extract, stir;
When temperature is down to 40 �� 2 DEG C, add phenoxyethanol and essence, mix homogeneously, stop when temperature is 35 DEG C stirring.
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| CN107184460A (en) * | 2017-05-22 | 2017-09-22 | 邵洁明 | A kind of cucumber mildy wash |
| CN107496283A (en) * | 2017-08-18 | 2017-12-22 | 苏州莱奥生物技术有限公司 | A kind of Chinese herbal medicine antiallergic mildy wash |
| CN107648137A (en) * | 2017-09-30 | 2018-02-02 | 朱耀灯 | A kind of mildy wash |
| CN115887265A (en) * | 2022-11-03 | 2023-04-04 | 青蛙王子（福建）婴童护理用品有限公司 | JAK1 signal channel inhibitor and application thereof in anti-inflammatory and soothing cosmetics |
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