CN105617281A - 治疗反流性食管炎的中药组合物 - Google Patents

治疗反流性食管炎的中药组合物 Download PDF

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CN105617281A
CN105617281A CN201610129780.9A CN201610129780A CN105617281A CN 105617281 A CN105617281 A CN 105617281A CN 201610129780 A CN201610129780 A CN 201610129780A CN 105617281 A CN105617281 A CN 105617281A
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reflux esophagitis
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于祝先
刘东彦
于小涵
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Abstract

本发明涉及一种药物配方领域，具体地说是一种治疗反流性食管炎的中药组合物，其特征是，原料组成以重量百分比计为：黄芪8～12％、苏梗6～9％、旋覆花5～7％、白术5～8％、天冬4～7％、鹅不食草4～6％、连翘3～5％、全瓜蒌4～6％、川芎5～7％、郁金3～5％、山奈4～6％、半边莲4～6％、鳢肠4～6％、王不留行3～5％、龙眼梳3～6％、蒲公英4～6％、栀子2～5％、通奶草4～6％、大还魂草5～7％，将上述19味原料药用水浸泡，煎熬后去渣得滤液。本发明疗效高，无毒副作用，不易复发。

Description

治疗反流性食管炎的中药组合物
技术领域
本发明涉及一种中成药制剂，具体地说是一种治疗反流性食管炎的中药组合物。
背景技术
众所周知，反流性食管炎是胃或十二指肠内容物反流到食管，造成食管粘膜损伤的胃肠动力障碍性疾病。临床表现为上腹部或胸骨后烧灼感或疼痛，常发生于餐后平卧或腹内压增加时，直立或服制酸剂可缓解。重症患者可出现间歇性甚至持续性吞咽困难和呕吐。随着生活水平的提高，其发病率有升高的趋势，严重影响着人们的身体健康和生活质量。西医内科常规治疗是以抗酸，促胃动力，粘膜保护为主，但普遍存在费用高，副作用大，疗程长，易复发等情况。
发明内容
本发明所要解决的技术问题是为了克服现有技术的不足，提供一种治疗反流性食管炎的中药组合物，成本低，疗效高，无毒副作用，不易复发。
本发明解决上述技术问题采用的技术方案是：一种治疗反流性食管炎的中药组合物，其技术特征是，原料组成以重量百分比计为：黄芪8～12％、苏梗6～9％、旋覆花5～7％、白术5～8％、天冬4～7％、鹅不食草4～6％、连翘3～5％、全瓜蒌4～6％、川芎5～7％、郁金3～5％、山奈4～6％、半边莲4～6％、鳢肠4～6％、王不留行3～5％、龙眼梳3～6％、蒲公英4～6％、栀子2～5％、通奶草4～6％、大还魂草5～7％，将上述19味原料药用水浸泡，煎熬后去渣得滤液。
本发明的有益效果是，成本低，疗效高，无毒副作用，不易复发。
具体实施方式
下面结合实施例对本发明作进一步的描述：
实施例1：
采用黄芪、苏梗、旋覆花、白术、天冬、鹅不食草、连翘、全瓜蒌、川芎、郁金、山奈、半边莲、鳢肠、王不留行、龙眼梳、蒲公英、栀子、通奶草、大还魂草为原料制备而成。其组分(重量％)每付为黄芪9.9、苏梗6.5、旋覆花6.2、白术6.1、天冬5.5、鹅不食草5.5、连翘3.3、全瓜蒌4.9、川芎5.5、郁金3.4、山奈5.1、半边莲4.9、鳢肠5.1、王不留3.8、龙眼梳4.4、蒲公英5.1、栀子3.2、通奶草5.5、大还魂草6.1。取上述19种原料总重量为180克，在室温下将19种中草药加水至800～1000ml，浸泡3～5分钟，然后用武火煮沸文火煎熬90～100分钟左右，去渣得滤液200ml，药渣再加水250～300ml，煎熬30～40分钟，去渣得滤液100ml，共得300ml左右药汁，即制得汤剂。装入无菌玻璃瓶内，密封瓶盖备用，每日1剂分2次口服，每次空腹口服150ml左右，服用后临床症状体征消失，再巩固疗效服用1周。
本发明黄芪有增强机体免疫功能，保肝，利尿，抗衰老，抗应激，降压和较广泛的抗菌作用；苏梗理气宽中，止痛，安胎。用于胸膈痞闷，胃脘疼痛，嗳气呕吐；旋覆花降气，消痰，行水，止呕。用于风寒咳嗽，痰饮蓄结，胸膈痞满；白术具有健脾益气，燥湿利水，止汗，安胎的功效，用于脾虚食少，腹胀泄泻；天冬具有养阴清热，润肺滋肾的功效。用于治阴虚发热、肺痈、消渴等病症；鹅不食草具有发散风寒，通鼻窍，止咳，解毒，止痒等功效；连翘清热，解毒，散结，消肿。治温热，丹毒，斑疹，痈疡肿毒，瘰疬，小便淋闭；全瓜蒌清热涤痰，宽胸散结，润燥滑肠。用于肺热咳嗽，痰浊黄稠，胸痹心痛，结胸痞满，乳痈，肺痈，肠痈肿痛，大便秘结；川芎行气开郁，法风燥湿，活血止痛。治风冷头痛旋晕，胁痛腹疼；郁金活血止痛，行气解郁，清心凉血，利胆退黄；山奈温中化湿，行气止痛。用于胸腹冷痛，寒湿吐泻；半边莲具备利尿消肿，清热解毒等功效，能治疗大腹水肿、面足浮肿；鳢肠滋补肝肾、凉血止血，可治各种吐血，肠出血等症；王不留行具有活血通经，下乳消肿，利尿通淋的功效；龙眼梳理气止痛，健胃；蒲公英化热毒，消恶肿结核，解食毒，散滞气；栀子具有护肝、利胆、降压、镇静、止血、消肿等作用；通奶草清热利湿，收敛止痒。细菌性痢疾，肠炎腹泻；大还魂草宁心，健脾，散瘀，止血。
本发明各原料还可按下表所列比例(重量百分比)混合的实施例来实现。其加工工艺与实施例1相同。
下面结合我院进行的临床试验对本发明作进一步、详细地描述：
临床资料
1、一般资料80例患者均符合反流性食管炎诊断标准，男40例，女40例，年龄25～54岁，病程5个月～5年。
2、诊断标准(1)与体位改变有关的烧灼样胸骨后痛；(2)胃内容物反流及吞咽困难；(3)食管内PH监测、食管压力测定及X线吞钡检查提示下括约肌有关闭功能不全。(4)内镜检查和粘膜活检或滴酸试验证实有炎症存在。
3、治疗方法患者服用实施例1汤剂，每日1剂分2次口服，每次空腹口服150ml左右；15天一疗程，连续治疗3个疗程。
4、疗效标准治愈：临床症状消失，胃镜检查：胃与食管连接处粘膜正常；显效：临床症状基本消失，胃与食管连接处粘膜溃疡消失，充血水肿减轻，渗出物减少；有效：临床症状减轻，胃与食管粘膜充血水肿有所减轻；无效：临床症状无明显改善，胃与食管粘膜无改变或加重。
5、治疗结果80例患者治疗3个疗程后观察疗效，其中治愈40例，显效22例，有效16例，无效2例，总有效率97.5％。

Claims (1)

1.一种治疗反流性食管炎的中药组合物，其特征在于，由如下重量百分比的原料药制成：黄芪8～12％、苏梗6～9％、旋覆花5～7％、白术5～8％、天冬4～7％、鹅不食草4～6％、连翘3～5％、全瓜蒌4～6％、川芎5～7％、郁金3～5％、山奈4～6％、半边莲4～6％、鳢肠4～6％、王不留行3～5％、龙眼梳3～6％、蒲公英4～6％、栀子2～5％、通奶草4～6％、大还魂草5～7％，将上述19味原料药用水浸泡，煎熬后去渣得滤液。
CN201610129780.9A 2016-02-22 2016-02-22 治疗反流性食管炎的中药组合物 Pending CN105617281A (zh)

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