CN104740042A - 一种治疗慢性咽炎的中药组合物 - Google Patents
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Abstract
本发明涉及一种治疗慢性咽炎的药物，尤其涉及一种以植物中草药为原料制成的治疗慢性咽炎的中药组合物。其特征在于，制成有效成分的原料药按照下述重量为：焦山楂10-20份，丹参5-20份，罗汉果1-10份，生地10-30份，黄芪10-15份，连翘10-20份，薄荷5-15份，当归5-20份，蝉蜕5-15份，栀子10-15份。本发明的诸药配伍，相得益彰，具有清热解毒，消肿利咽，补中益气，健脾和胃，缓急止痛，理气降逆，燥湿化痰等功效，药效的协同作用，无副作用，对虚火上炎，肺脾气虚，痰热，痰瘀互阻等病症引起的慢性咽炎起到了根治作用。
Description
技术领域
本发明涉及一种治疗慢性咽炎的药物，尤其涉及一种以植物中草药为原料制成的治疗慢性咽炎的中药组合物。
背景技术
慢性咽炎是一种常见病，多发于成年人，为慢性感染所引起的弥漫性眼部病变，主要是咽部粘膜炎症，一般是由屡发急性咽炎、长期粉尘或有害气体刺激、烟酒过度或其他不良生活习惯、鼻窦炎分泌物刺激、过敏体质或身体抵抗力减低等原因所致。慢性咽炎也可以是某些全身性疾病的局部表现，如贫血、糖尿病、肝硬化及慢性肾炎等。慢性咽炎的症状是咽部不适，有异物感，总感到咽部有咽不下又吐不出的东西，刺激咳嗽，干燥、发胀、堵塞、瘙痒等症。引起慢性咽炎的病因很多，如全身疾病，邻近器官疾病，气候，季节因素，病原微生物等原因导致人体抵抗力下降，咽部血液循环障碍而引起慢性咽炎。慢性咽炎在临床上是一种常见病、多发病，在常规的药物治疗中比较顽固，且反复发作，感冒加重。中医认为，慢性咽炎是由虚火上炎，肺脾气虚，痰热，痰瘀互阻等病症引起。目前，治疗慢性咽炎的方法很多，有中成药，茶饮，西药。中成药，药的成分含量较低，因其病程长，症状顽固，短期难见显效，西药，主要是抗生素类药，以消炎为主，见效快，但对身体有毒副作用，长期用药，带来的结果往往是身体机能退化和药物抵抗，会使身体产生不良反应，后期较容易复发，或者治标不治本。因此本发明特优选采用了一种治疗慢性咽炎的中药组合物。
发明内容
本发明目的就是针对现有治疗慢性咽炎病症存在的技术不足，提供了一种专治慢性咽炎的中药组合物，具有清热利咽、消肿止痛的功效，价格低廉，组方简单，可有效的根治慢性咽炎，使其不再复发。
本发明解决其技术问题所采用的技术方案是：一种治疗慢性咽炎的中药组合物，其特征在于，制成有效成分的原料药按下述重量为：焦山楂10-20份，丹参5-20份，罗汉果1-10份，生地10-30份，黄芪10-15份，连翘10-20份，薄荷5-15份，当归5-20份，蝉蜕5-15份，栀子10-15份。
用法：一天一剂，水煎服，可分两次服用，对于服中药困难的患者，可以少量多次的分服。
药理作用
焦山楂：消食健胃，行气散瘀。用于肉食积滞，胃脘胀满，泻痢腹痛，瘀血经闭，产后瘀阻，心腹刺痛，疝气疼痛；高脂血症。
丹参：活血祛瘀，安神宁心，排脓，止痛。治心绞痛，月经不调，痛经，经闭，血崩带下，百瘕，积聚，瘀血腹痛，骨节疼痛，惊悸不眠，恶疮肿毒。
罗汉果：主治咳嗽咽干，声嘶，大便秘结，失眼，痛经，关节痛，痢疾。
生地：清热凉血，养阴，生津。用于热病烦渴、发斑发疹、阴虚内热、吐血、衄血、糖尿病。
黄芪：补气固表，利尿托毒，排脓，敛疮生肌。用于气虚乏力，食少便溏，中气下陷，久泻脱肛，便血崩漏，表虚自汗，气虚水肿，痈疽难溃，久溃不敛，血虚痿黄，内热消渴；慢性肾炎蛋白尿，糖尿病。
连翘：清热、解毒、散结、消肿。治温热，丹毒，斑疹，痈疡肿毒，瘰疬，小便淋闭；咽喉肿痛，风疹。
薄荷：疏风，散热，辟秽，解毒。治外感风热，头痛，目赤，咽喉肿痛，食滞气胀，口疮，牙痛，疮疥，瘾疹。
当归：补血和血，调经止痛，润燥滑肠。治月经不调，经闭腹痛，百瘕结聚，崩漏；血虚头痛，眩晕，痿痹；肠燥便难，赤痢后重；痈疽疮窃，跌扑损伤。
蝉蜕：散风热，宣肺，定痉。治外感风热，咳嗽音哑，麻疹透发不畅，风疹瘙痒，小儿惊痫，目赤，翳障，疔疮肿毒，破伤风。
栀子： 清热，泻火，凉血。治热病虚烦不眠，黄疸，淋病，消渴，目赤，咽痛，吐血，衄血，血痢，尿血，热毒疮疡，扭伤肿痛。
本发明的有益效果是，本发明的每味中药之间，通过数次临床组方配伍后得出，诸药配伍，相得益彰，服用药物后，药物从人的总体入手，具有利咽润肺，补中益气，疏肝和胃，消炎镇痛，理气降逆，燥湿化痰等功效。药效的协同作用，无副作用，对虚火上炎，肺脾气虚，痰热，痰瘀互阻等病症引起的慢性咽炎起到了根治作用。
毒性试验
试验方法
取SD大鼠20只，体重180-220g，将大鼠平均分成两组，雌雄各半，分别喂食本发明实施例和生理盐水。
药物喂食方法为
将本发明药物研成粉末，用水配成混悬液。每组大鼠每天三次灌胃，第一组灌胃药物混悬液，第二组灌胃生理盐水，每天大鼠用药量为1.5g/Kg，大鼠禁食不禁水，照此方法连续灌胃15天。
试验结果
在大鼠用药期间，大鼠均无中毒、死亡现象，两组大鼠活动、食欲正常。经解剖肾脏、肝脏、肾上腺皮质、生殖器均无明显变化。
试验结论
从上述结果可以看出，动物实验所用药物远远高出成人临床用药的药量，但大鼠无死亡或器官变异状况发生，因此可以得出本发明药物在人体使用时无毒副作用。
临床实验：
一般资料
在本市就诊人员中选取40例慢性咽炎疾病患者，患者均具有以下主要症状和体征：咽部干燥或痒、微痛、异物感、刺激性干咳等；检查见咽黏膜肿胀或有树枝状充血，咽侧索肥厚，咽后壁淋巴滤泡增生等，将这40例病患采用随机数字表方法随机分为两组。其中，对照组20例，男性14例，女性6例，病患者年龄在31-58岁，平均年龄36岁；治疗组20例，男性13例，女性7例，病患者年龄在30-56岁，平均年龄35岁。
疗效评定标准
治愈：自觉症状消失或基本消失，咽部粘膜充血消失；
有效：症状明显减轻，咽部粘膜充血有所消退；
无效：症状体征无改善。
对于对照组慢性咽炎患者给予草珊瑚含片或西瓜霜予以治疗；对于治疗组的给予本分明中药组合物治疗。
观察一个月，治疗效果如下：
通过以上的对比可以得出，本发明中药组合物的疗效好，治疗时间短。
部分患者病例如下：
高某，男，36岁，患者2年前因感冒，咽部干燥疼痛，咽部充血，声音嘶哑，经治疗数月，声哑不除。证见慢性病容，咽部微红，灼热疼痛，咳痰不利，声音嘶哑，舌红，舌苔微黄，脉滑数。诊断为慢性咽炎。使用本发明中药，2个疗程后治愈，巩固治疗1个疗程，随访至今未复发。
潘某，女，41岁。自述咽炎反复发作，咽干痛，牙龈痛，咳嗽，咽部长期有异物感，声音嘶哑，便干，黄涕，舌红少津，有裂纹，舌苔薄黄，脉弦。服用本发明中药组合物1个疗程，症状减轻，服用3个疗程后症状全部消失，巩固半个疗程，随访至今未复发。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
实施例1
称取焦山楂20份，丹参20份，罗汉果10份，生地30份，黄芪15份，连翘20份，薄荷15份，当归20份，蝉蜕15份，栀子15份，按照常规方法制成口服汤剂。
实施例2
优选称取焦山楂15份，丹参13份，罗汉果5份，生地20份，黄芪15份，连翘18份，薄荷14份，当归15份，蝉蜕10份，栀子14份，按照常规方法制成口服汤剂。
实施例3
进一步优选称取焦山楂10份，丹参5份，罗汉果1份，生地10份，黄芪10份，连翘10份，薄荷5份，当归5份，蝉蜕5份，栀子10份，按照常规方法制成口服汤剂。
先将药物用水洗净，再用冷水浸泡20-30分钟，使药物完全被水浸透，便于有效成分的溶解，然后将药物放在砂锅、陶瓷或者瓦罐之类的器皿里（不可以用铁锅和铝锅），加上为药物5-10倍的水，或者比药面高出2-3厘米左右。煎第一遍时，用大火加热到100℃左右时，改用小火加热30分钟就好，将药汤倒在器皿里，再煎第二遍。煎第二遍的方法同第一遍一样，只是时间可以稍微短一些。煎完以后，把这两次煎出的药汤混合在一起服用，总量在300-500毫升，这样可以使药物之间充分作用，有效成分溶出彻底，增强疗效。
Claims (4)
1.一种治疗慢性咽炎的中药组合物，其特征在于，制成有效成分的原料药按下述重量份为：焦山楂10-20份，丹参5-20份，罗汉果1-10份，生地10-30份，黄芪10-15份，连翘10-20份，薄荷5-15份，当归5-20份，蝉蜕5-15份，栀子10-15份。
2.根据权利要求1所述治疗慢性咽炎的中药组合物，其特征在于，制成有效成分的原料药按下述重量份为：焦山楂20份，丹参20份，罗汉果10份，生地30份，黄芪15份，连翘20份，薄荷15份，当归20份，蝉蜕15份，栀子15份。
3.根据权利要求1所述治疗慢性咽炎的中药组合物，其特征在于，制成有效成分的原料药按下述重量份为：焦山楂15份，丹参13份，罗汉果5份，生地20份，黄芪15份，连翘18份，薄荷14份，当归15份，蝉蜕10份，栀子14份。
4.根据权利要求1所述治疗慢性咽炎的中药组合物，其特征在于，制成有效成分的原料药按下述重量份为：焦山楂10份，丹参5份，罗汉果1份，生地10份，黄芪10份，连翘10份，薄荷5份，当归5份，蝉蜕5份，栀子10份。
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075310A (zh) * | 2016-07-29 | 2016-11-09 | 黄志建 | 一种治疗咽喉炎的中药药物 |
| CN106215045A (zh) * | 2016-07-29 | 2016-12-14 | 黄志建 | 一种治疗咽喉炎的中药组合物 |
| CN106581428A (zh) * | 2016-11-10 | 2017-04-26 | 傅天锡 | 治疗慢性咽炎的药物 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075310A (zh) * | 2016-07-29 | 2016-11-09 | 黄志建 | 一种治疗咽喉炎的中药药物 |
| CN106215045A (zh) * | 2016-07-29 | 2016-12-14 | 黄志建 | 一种治疗咽喉炎的中药组合物 |
| CN106581428A (zh) * | 2016-11-10 | 2017-04-26 | 傅天锡 | 治疗慢性咽炎的药物 |
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