CN105581332A - Composition with skin moisture improving and antioxidation functions and preparation method - Google Patents
Composition with skin moisture improving and antioxidation functions and preparation method Download PDFInfo
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- CN105581332A CN105581332A CN201511014827.9A CN201511014827A CN105581332A CN 105581332 A CN105581332 A CN 105581332A CN 201511014827 A CN201511014827 A CN 201511014827A CN 105581332 A CN105581332 A CN 105581332A
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- astaxanthin
- collagen
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- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
- 230000031068 symbiosis, encompassing mutualism through parasitism Effects 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Composition with skin moisture improving and antioxidation functions is prepared from components in parts by weight as follows: 3-80 parts of collagen, 0.02-10 parts of astaxanthin, 0.02-30 parts of sodium hyaluronate, 0.1-60 parts of vitamin C, 2-60 parts of water-soluble dietary fiber and 1-90 parts of an auxiliary. The collagen, the astaxanthin, sodium hyaluronate, vitamin C and the water-soluble dietary fiber have a synergistic effect, and the composition has the efficacy of skin moisturizing, antioxidation, senescence delaying and the like.
Description
Technical field
The present invention relates to health food technology field, particularly one and can supplement moisture of skin, make body there is the health food of anti-oxidation function.
Background technology
Skin belongs to connective tissue, has from outside to inside epidermis, corium, hypodermis three part compositions. The network structure that skin corium is made up of materials such as collagen, elastin, hyaluronic acid and capilaries, wherein collagen and elastin play support, make it to have good consolidation and elasticity. Sodium Hyaluronate can pin the moisture of skin as NMF. Consultant doctor Andrew doctor Lai Te of dept. of dermatology according to Britain's Bradford national health service trust (BradfordNHSTrust) introduces, women generates Sodium Hyaluronate and collagen during since 20 years old speed in body slows down, add and can allow the elastin laminin elasticity that skin rebounds rapidly reduce, these materials in skin are run off year by year, during by 40 years old, content reduces to half, skin histology atrophy, form gap, the aging phenomenons such as that skin manifests is lax, wrinkle, dry, coarse, pore is thick. But not only just the growth at age is so simple again in the variation of skin, it is by age, heredity, do not have enough sleep, the result of factors in many ways such as diet, solar radiation, dust, environmental pollution, psychological pressure. And the injury of the radical pair skin producing in environment is also key factor. Free radical is the health of harmful to human not only, and it is gone back and numerous disease comprises that artery sclerosis, heart disease, tumour, diabetes, senile dementia etc. all exist direct or potential contact. Along with deepening continuously that people are familiar with free radical, the oxidation resistant product with removing free radical effect is more and more subject to people's attention.
People are that the situation of improving skin is focused on making to apply some make up traditionally, and start now to focus on taking good care of of body interior, and beautiful pursuit is trended towards to " from outside to inside ". Confirm by the material such as oral collagen and Sodium Hyaluronate through a large amount of clinical experimental studies, can increase its content in skin, can reach water conservation, anti-oxidant, the physiological function that delays senility, thereby eliminate wrinkle of skin, delay skin aging, than the better effects if of utilizing spreading upon on skin surface. Patent CN201110318016.3 has announced a kind of composition and method of making the same that contains haematococcus extract and collagen peptide, it is grouped together astaxanthin and collagen peptide to make capsule, but both combinations do not solve the substantive issue of human senility from root, undesirable for oxidation resistant effect of moisturizing of skin. Therefore how effectively to eliminate unnecessary free radical in body, supplement skin moisture, strengthen antioxidant ability of organism, delay senility and become urgently to be resolved hurrily and there is the problem of realistic meaning.
Summary of the invention
Technical problem to be solved by this invention is the defect that overcomes prior art, a kind of the have composition and the preparation method that improve moisture of skin and anti-oxidation function are provided, collagen in composition, astaxanthin, Sodium Hyaluronate, water-soluble dietary fiber and vitamin C synergy, have moisturizing, anti-oxidant, the effect such as delay senility.
Technical problem of the present invention realizes with following technical proposals:
A kind of have a composition that improves moisture of skin and anti-oxidation function, component by following parts by weight is made: collagen 3-80 part, astaxanthin 0.02-10 part, Sodium Hyaluronate 0.02-30 part, vitamin C 0.1-60 part, water-soluble dietary fiber 2-60 part, auxiliary material 1-90 part.
Above-mentioned have a composition that improves moisture of skin and anti-oxidation function, and described auxiliary material comprises sweetener, acid, flavouring, colouring agent, diluent and lubricant.
Above-mentioned have a composition that improves moisture of skin and anti-oxidation function, component by following parts by weight is made: collagen 10-60 part, astaxanthin 0.05-7.5 part, Sodium Hyaluronate 0.05-20 part, Catergen-30 part, water-soluble dietary fiber 5-20 part, sweetener 0.2-5 part, acid 0.2-30 part, flavouring 0.5-5 part, colouring agent 0.001-2 part, diluent 2-30 part, lubricant 0.3-2 part.
Above-mentioned have a composition that improves moisture of skin and anti-oxidation function, and described collagen is the one in collagen, fish-bone collagen, ossein oligopeptide; Described astaxanthin is the one in haematococcus pluvialis powder, astaxanthin oil or astaxanthin powder; Described vitamin C is the one in L-AA, ascorbic acid-6-palmitate, sodium ascorbate, Calcium Ascorbate; Described water-soluble dietary fiber comprises the one in xylo-oligosaccharide, FOS, oligoisomaltose.
A preparation method for described composition, comprises the steps:
A. preparation: take respectively each former, auxiliary material by formula ratio, vitamin C, acid were pulverized respectively to 100 mesh sieves, for subsequent use;
B. granulate: the collagen of formula ratio, vitamin C and acid are mixed, granulation, dry under the condition of 40 DEG C-50 DEG C;
C. mix: the astaxanthin powder of formula ratio, Sodium Hyaluronate, water-soluble dietary fiber are carried out to premixed, obtain pre-composition, the particle that step b is made and pre-composition add in mixer, mix and make hybrid particles discharging after 30 minutes;
D. preparation: the formulation of the hybrid particles of step c being made to tablet, effervescent tablet, granule and capsule.
The preparation method of above-mentioned composition, described astaxanthin powder is the microcapsule powder that the natural astaxanthin oil that extracts from haematococcus pluvialis is made through micro-capsule embedding techniques.
The preparation method of above-mentioned composition, the preparation method of described effervescent tablet comprises the steps:
A. preparation: take respectively each supplementary material by batch formula ratio, vitamin C, acid were pulverized respectively to 100 mesh sieves, for subsequent use;
B. granulate: the collagen of formula ratio, vitamin C, diluent and acid are mixed, the PVP ethanol solution granulation one that is 5% by concentration, the temperature of 40-50 DEG C is dried; Two, 60 DEG C of the PVP ethanol solution granulations that is 5% by concentration by sodium acid carbonate are dry;
C. mix: astaxanthin powder, Sodium Hyaluronate, water-soluble dietary fiber, sweetener, flavouring are carried out to premixed, obtain pre-composition; Two kinds of made particles, pre-composition and lubricants of above-mentioned steps b add in mixer, mix and make hybrid particles discharging after 30 minutes;
D. compressing tablet: the hybrid particles of step c is carried out to compressing tablet with tablet press machine, be finished product after packaging.
The present invention is to adopt the collagen, hyaluronic acid, vitamin C of endogenous effect as basis, be equipped with again and there is the astaxanthin of strong antioxidant action and regulate the microcirculatory dietary fiber of body, the health food of making not only delays the situation that middle-aged and old physique declines, can also increase bone density, strengthen immunity, angiocardiopathy preventing, can improve the variety of issue that the elderly is old and feeble comprehensively. Through the evidence of animal and human's body, composition function is definite, have no side effect, and adult can long-term taking.
Between each component, collaborative playing a role, strengthens effect of moisturizing antioxygen. Wherein collagen can accelerate skin corium Growth of Cells, activate epidermal cell, and its triple-helix structure forms elasticated net closely and pins the moisture content in skin; The effect that collagen also has strong bone, improves body immunity, improves sleep quality. It is a kind of acid mucopolysaccharide that hyaluronic acid (Hyaluronicacid, HA) has another name called sodium hyaluronate, is NMF, can delay senility, and maintains the water balance of skin environment. Astaxanthin is that unique that the mankind find up to now can be by the powerful antioxidant of blood-brain barrier; its antioxidation activity far exceedes existing antioxidant, also has protection blood vessel, reduction cholesterol, vision protection, prevention senile dementia, alleviates many-sided nutrition health-care functions such as arthralgia. Vitamin C is water soluble antioxidant, can eliminate the toxicity of harmful oxygen radical, promotes collagen to absorb. Water-soluble dietary fiber has the human body of adjusting microecological balance, relaxes bowel, reduces cholesterol, regulates the health cares such as blood sugar, blood fat, and do not occur the disadvantageous physical and chemical reaction of human body with other compositions, in improving products taste, improve product stability. Above-mentioned each component not only can be supplemented the exogenous water conservation polyphenoils that human body needs, its increase that can improve the endogenous water conservation polyphenoils in body of what is more important, promote exogenous and endogenous polyphenoils acting in conjunction, form the oxidation resistant symbiosis ring of water conservation, make it aspect moisturizing, antioxygen, produce efficient comprehensively comprehensive effect.
In preparation technology, utilize embedding techniques, emulsifying technology and taste masking technology to make different dosage form, not only taste sweet and sour taste can meet different consumer demands, and vitamin C and collagen are passed through to PVP embedding granulation, solve the unstable difficult problem of raw material, its functional component is easily absorbed, improved the quality stability of bioavilability and product.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.
A kind of have a composition that improves moisture of skin and anti-oxidation function, it is made up of the component of following weight portion: collagen 3-80 part, astaxanthin 0.02-10 part, Sodium Hyaluronate 0.02-30 part, vitamin C 0.1-60 part, water-soluble dietary fiber 2-60 part, auxiliary material 1-90 part. Auxiliary material is in sweetener 0-10 part of parts by weight, acid 0-40 part, flavouring 0-5 part, colouring agent 0-5 part, diluent 0-40 part, lubricant 0-3 part.
The optimization formula of composition is: collagen 10-60 part, astaxanthin 0.05-7.5 part, Sodium Hyaluronate 0.05-20 part, Catergen-30 part, water-soluble dietary fiber 5-20 part, auxiliary material 10-50 part. Auxiliary material is in sweetener 0.2-5 part of parts by weight, acid 0.2-30 part, flavouring 0.2-5 part, colouring agent 0.001-2 part, diluent 2-30 part, lubricant 0.3-2 part.
Described collagen is the one in collagen, fish-bone collagen, ossein oligopeptide. Described astaxanthin is the one in haematococcus pluvialis powder, astaxanthin oil or astaxanthin powder. Astaxanthin powder be the natural astaxanthin oil that extracts from haematococcus pluvialis through micro-capsule embedding techniques, astaxanthin is made to the microcapsule powder of good stability. Make astaxanthin water-soluble through embedding techniques, good absorbing effect. Described Sodium Hyaluronate is oral level Sodium Hyaluronate. Described vitamin C is the one in L-AA, ascorbic acid-6-palmitate, sodium ascorbate, Calcium Ascorbate. Described water-soluble dietary fiber comprises the one in xylo-oligosaccharide, FOS, oligoisomaltose.
Described auxiliary material comprises sweetener, acid, flavouring, colouring agent, diluent and lubricant, described diluent comprises one or more in D-sorbite, xylitol, antierythrite, sweet mellow wine, described acid comprises one or more in citric acid, malic acid, gluconic acid, tartaric acid, fumaric acid, glutamic acid, described flavouring comprises orange flavor or fruit powder, peach flavor or fruit powder, grape essence or fruit powder, milk essence or milk powder, and described pigment comprises carmine pigment or color lake, light green pigment or color lake. Lubricant is superfine silica gel powder, dolomol, Macrogol 6000.
Composition can be made into tablet, capsule, granule, oral liquid, powder. Capsule refers to hard shell capsules, soft capsule. When preparation, according to different dosage form technology of preparing difference used, comprise embedding, emulsification, taste masking technology.
Embodiment 1
Prepare lozenge
Take the component of following weight portion: 37.5 parts of collagens, 7.5 parts, astaxanthin powder, 3.75 parts of Sodium Hyaluronates, 3 parts of vitamin Cs, 6.25 parts of xylo-oligosaccharides, 33.48 parts of D-sorbites, 3 parts of L MALIC ACIDs, 1.5 parts, blueberry essence, 3 parts of Aspartames, 0.02 part, the red aluminium of lac color lake, 1 part of dolomol.
Preparation method:
(1) adhesive preparation: compound concentration is 5%(m:v) polyvinylpyrrolidone (PVP-K30) ethanol solution, for subsequent use.
(2) pulverize: vitamin C, L MALIC ACID are pulverized respectively with pulverizer, for subsequent use.
(3) sieve: the vitamin C after above-mentioned pulverizing, L MALIC ACID are crossed respectively to 100 mesh sieves; For subsequent use.
(4) weigh: take respectively each supplementary material by batch formula ratio, put in cleaning container, for subsequent use.
(5) granulate: formula ratio collagen, vitamin C, L MALIC ACID are mixed, and with 5% PVPK30 ethanol solution softwood processed, 30 orders are granulated, and 40-50 DEG C is dry, the whole grain of 20 orders.
(6) mix: premixed is carried out in astaxanthin powder, Sodium Hyaluronate, water-soluble dietary fiber, orange flavor, Aspartame, the red aluminium of lac color lake, obtain pre-composition; Above-mentioned made particle, pre-composition, dolomol are added in mixer, mix 30 minutes, mix rear discharging in cleaning container. By quality standard inspection intermediate total mixture moisture≤5%.
(7) compressing tablet: get qualified hybrid particles, determine sheet weight, carry out compressing tablet with tablet press machine.
(8) packaging: the sheet that will be up to the standards is sent into packaging process. In packaging post, pack with polyethylene bottle or aluminium foil bubble-cap on request. Through putting in storage after the assay was approved, be finished product.
Embodiment 2
Prepare effervescent tablet
Take the component of following weight portion: 25 parts of collagens, 2 parts, astaxanthin powder, 2 parts of Sodium Hyaluronates, 5 parts of vitamin Cs, 5 parts of FOSs, 24.3 parts of citric acids, 20 parts of sodium acid carbonates, 13.2 parts, sweet mellow wine, 0.5 part of peach flavor, 1 part of Aspartame, 2 parts of Macrogol 6000s.
Preparation method:
(1) adhesive preparation: the PVPK30 ethanol solution of preparation 5%, for subsequent use.
(2) pulverize: vitamin C, citric acid are pulverized respectively with pulverizer, for subsequent use.
(3) sieve: the vitamin C after above-mentioned pulverizing, citric acid are crossed respectively to 100 mesh sieves, for subsequent use.
(4) weigh: take respectively each supplementary material by batch formula ratio, put in cleaning container, for subsequent use.
(5) granulate: the collagen of formula ratio, vitamin C, sweet mellow wine, citric acid are mixed, and with 5% PVPK30 ethanol solution softwood processed, 30 orders are granulated, and 40-50 DEG C is dry, the whole grain of 20 orders. 5% PVPK30 ethanol solution softwood processed for sodium acid carbonate, 30 orders are granulated, and 60 DEG C are dry, the whole grain of 20 orders.
(6) mix: astaxanthin powder, Sodium Hyaluronate, water-soluble dietary fiber, peach flavor, Aspartame are carried out to premixed, obtain pre-composition; Above-mentioned made particle, pre-composition, Macrogol 6000 are added in mixer, mix 30 minutes, mix rear discharging in cleaning container. By quality standard inspection intermediate total mixture moisture≤3%.
(7) compressing tablet: get qualified hybrid particles, determine sheet weight, carry out compressing tablet with tablet press machine.
(8) packaging: the sheet that will be up to the standards is sent into packaging process. In packaging post, pack with polyethylene bottle or aluminum-plastic composite membrane on request. Through putting in storage after the assay was approved, be finished product.
Embodiment 3
Prepare granule
Take the component of following weight portion: 60 parts of collagens, 1.5 parts, astaxanthin powder, 1.7 parts of Sodium Hyaluronates, Catergen .5 part, 8 parts of FOSs, 22.1 parts of antierythrites, 3.5 parts of L MALIC ACIDs, 0.2 part of orange flavor, 0.5 part of Aspartame.
Preparation method:
(1) pulverize: vitamin C, L MALIC ACID are pulverized with pulverizer respectively, crossed 100 mesh sieves, for subsequent use.
(2) weigh: take respectively each supplementary material by formula ratio, put in cleaning container, for subsequent use.
(3) granulate: the collagen of formula ratio, vitamin C, antierythrite, L MALIC ACID are mixed, and with absolute ethyl alcohol softwood processed, 30 orders are granulated, and 40-50 DEG C is dry, the whole grain of 20 orders.
(4) mix: astaxanthin powder, Sodium Hyaluronate, water-soluble dietary fiber, orange flavor, Aspartame are carried out to premixed by mixing method progressively, add in mixer with above-mentioned made particle afterwards, total mixing 30 minutes, mix rear discharging in cleaning container. By quality standard inspection intermediate total mixture moisture≤5%.
(5) packing: get qualified hybrid particles, determine that bag is heavy, carry out packing with particle packaging machine.
(6) packaging: qualified granule is sent into packaging process. In packaging post, pack with aluminum-plastic composite membrane on request. Through putting in storage after the assay was approved, be finished product.
Embodiment 4
Prepare oral liquid
Take the component of following weight portion: 20 parts of collagens, 0.5 part, astaxanthin powder, 0.2 part of Sodium Hyaluronate, 0.4 part of vitamin C, 3 parts of FOSs, 5 parts of xylitols, 0.5 part of L MALIC ACID, 0.01 part, mango essence, 0.02 part of Sucralose (sweetener), 70.37 parts of purified water.
Preparation method:
(1) raw material: from raw material storage, get the supplementary material being up to the standards, after sloughing external packing between the buffering of production area, enter clean area, for subsequent use;
(2) batching, constant volume, filtration: take each supplementary material by formula rate, each personal appropriate purified water is dissolved, and stirs; Be settled to formula ratio by purified water, stir, stand-by. Above-mentioned solution is filtered with flame filter press, for subsequent use.
(3) oral liquid bottle, lid lotion: drinking water for oral liquid bottle, lid is rinsed to twice, then rinse twice, 75% alcohol immersion sterilizing 1 hour by purified water. Dry.
(4) embedding: configuration liquid is sub-packed in brown oral liquid bottle by product specification.
(5) sterilizing: steam sterilizing.
(6) packaging: after passed examination, external packing. Warehouse-in, is finished product after the assay was approved.
Embodiment 5
Prepare capsule
Take the component of following weight portion: 55 parts of collagens, 4 parts, astaxanthin powder, 10 parts of Sodium Hyaluronates, 0 part of Catergen, 9.5 parts of oligomeric maltoses, 1.5 parts of superfine silica gel powders.
Preparation method:
(1) pulverize: vitamin C is pulverized with pulverizer, crossed 100 sieves, for subsequent use.
(2) weigh: take respectively each supplementary material by formula ratio, put in cleaning container, for subsequent use.
(3) granulate: by the collagen of formula ratio, with 5% PVPK30 absolute ethyl alcohol softwood processed, 30 orders are granulated, and 40-50 DEG C is dry, the whole grain of 20 orders.
(4) mix: astaxanthin powder, Sodium Hyaluronate, vitamin C, water-soluble dietary fiber are carried out to premixed, obtain pre-composition; Collagen particle, pre-composition, superfine silica gel powder are added in mixer, mix 30 minutes, mix rear discharging in cleaning container. By quality standard inspection intermediate total mixture moisture≤5%.
(5) packing: get qualified hybrid particles, determine that grain is heavy, carry out packing with capsule machine.
(6) packaging: the capsule that will be up to the standards is sent into packaging process. In packaging post, pack with aluminum plastic film on request. Warehouse-in, is finished product after the assay was approved.
Embodiment 6
Prepare soft capsule
Take the component of following weight portion: 50 parts of collagens, 0.2 part of astaxanthin oil, 5 parts of Sodium Hyaluronates, 4 parts of vitamin Cs, 40.8 parts, olive oil.
Preparation method:
(1) weigh: take each supplementary material by formula ratio, for subsequent use.
(2) batching: the olive oil of formula ratio is put into while heating to 60-70 DEG C in material-compound tank, add astaxanthin oil, the Sodium Hyaluronate mix and blend 30min of formula ratio, again the collagen of formula ratio is joined to mix and blend 30min in above-mentioned feed liquid, obtain mixed liquor. With colloid mill grinding, feed liquid is uniformly dispersed. Feed liquid after grinding is carried out to vacuum outgas, until the bubble in feed liquid is all to the greatest extent de-, obtain capsule 's content.
(3) colloidal sol: by the purified water of formula ratio, putting into of glycerine glue tank, glue tank temperature to be changed reaches 55-60 DEG C, drop into gelatin, the titanium dioxide of formula ratio, under stirring, continue heat up and keep 70-80 DEG C, after gelatin all dissolves, stop heating, vacuumize, the degassed bubble of removing, in heat insulation tank, 55-65 DEG C of insulation is for subsequent use.
(4) pelleting: content feed liquid and glue are made to soft capsule by encapsulating machine, according to content loading amount pelleting. In pelleting process, monitoring content thing weight, guarantees that weight differential is in acceptability limit, checks at any time capsule outward appearance, and whether ball type is normal, has ne-leakage. In production process, keep a close eye on the working order of equipment.
(5) sizing: the soft capsule that suppresses is moved in sizing drying rotating cage, shape under 20-24 DEG C, relative humidity 35-45%.
(6) wash ball: soft capsule 95% edible ethanol after sizing is washed to ball, remove the oil stain of capsule surface.
(7) dry: to indoor in clean dried in tray, to be 20-40% condition under static dry 22h at 24-28 DEG C, relative humidity by gained soft capsule.
(8) pick up ball: by visual method, product is screened, reject the special-shaped product in product.
(9) packaging: the capsule that will be up to the standards is sent into packaging process. In packaging post, pack with Packaging Bottle or aluminum-plastic blister on request. Through putting in storage after the assay was approved, be finished product.
Claims (7)
1. one kind has the composition that improves moisture of skin and anti-oxidation function, it is characterized in that, component by following parts by weight is made: collagen 3-80 part, astaxanthin 0.02-10 part, Sodium Hyaluronate 0.02-30 part, vitamin C 0.1-60 part, water-soluble dietary fiber 2-60 part, auxiliary material 1-90 part.
2. according to claim 1 have a composition that improves moisture of skin and anti-oxidation function, it is characterized in that, described auxiliary material comprises sweetener, acid, flavouring, colouring agent, diluent and lubricant.
3. according to claim 2 have a composition that improves moisture of skin and anti-oxidation function, it is characterized in that, component by following parts by weight is made: collagen 10-60 part, astaxanthin 0.05-7.5 part, Sodium Hyaluronate 0.05-20 part, Catergen-30 part, water-soluble dietary fiber 5-20 part, sweetener 0.2-5 part, acid 0.2-30 part, flavouring 0.5-5 part, colouring agent 0.001-2 part, diluent 2-30 part, lubricant 0.3-2 part.
4. according to claim 3 have a composition that improves moisture of skin and anti-oxidation function, it is characterized in that, described collagen is the one in collagen, fish-bone collagen, ossein oligopeptide; Described astaxanthin is the one in haematococcus pluvialis powder, astaxanthin oil or astaxanthin powder; Described vitamin C is the one in L-AA, ascorbic acid-6-palmitate, sodium ascorbate, Calcium Ascorbate; Described water-soluble dietary fiber comprises the one in xylo-oligosaccharide, FOS, oligoisomaltose.
5. according to a preparation method for composition described in claim 1-4 any one, it is characterized in that, comprise the steps:
A. preparation: take respectively each former, auxiliary material by formula ratio, vitamin C, acid were pulverized respectively to 100 mesh sieves, for subsequent use;
B. granulate: the collagen of formula ratio, vitamin C and acid are mixed, granulation, dry under the condition of 40 DEG C-50 DEG C;
C. mix: the astaxanthin powder of formula ratio, Sodium Hyaluronate, water-soluble dietary fiber are carried out to premixed, obtain pre-composition, the particle that step b is made and pre-composition add in mixer, mix and make hybrid particles discharging after 30 minutes;
D. preparation: the formulation of the hybrid particles of step c being made to tablet, effervescent tablet, granule and capsule.
6. the preparation method of composition according to claim 5, is characterized in that, described astaxanthin powder is the microcapsule powder that the natural astaxanthin oil that extracts from haematococcus pluvialis is made through micro-capsule embedding techniques.
7. the preparation method of composition according to claim 6, is characterized in that, the preparation method of described effervescent tablet comprises the steps:
A. preparation: take respectively each supplementary material by batch formula ratio, vitamin C, acid were pulverized respectively to 100 mesh sieves, for subsequent use;
B. granulate: the collagen of formula ratio, vitamin C, diluent and acid are mixed, the PVP ethanol solution granulation one that is 5% by concentration, the temperature of 40-50 DEG C is dried; Two, 60 DEG C of the PVP ethanol solution granulations that is 5% by concentration by sodium acid carbonate are dry;
C. mix: astaxanthin powder, Sodium Hyaluronate, water-soluble dietary fiber, sweetener, flavouring are carried out to premixed, obtain pre-composition; Two kinds of made particles, pre-composition and lubricants of above-mentioned steps b add in mixer, mix and make hybrid particles discharging after 30 minutes;
D. compressing tablet: the hybrid particles of step c is carried out to compressing tablet with tablet press machine, be finished product after packaging.
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| CN106617102A (en) * | 2017-01-17 | 2017-05-10 | 吉速利（上海）健康科技股份有限公司 | Collagen nutrient power and preparation method thereof |
| CN108404122A (en) * | 2018-04-24 | 2018-08-17 | 石家庄瑞大圣康生物科技有限公司 | A kind of composition and its technology of preparing of anti-aging |
| CN108543079A (en) * | 2018-05-22 | 2018-09-18 | 广东药科大学 | A kind of astaxanthin-collagen couplings and its preparation method and application |
| CN109007224A (en) * | 2018-10-16 | 2018-12-18 | 云南爱尔康生物技术有限公司 | A kind of pressed candy and preparation method thereof containing Astaxanthin In Haematococcus Pluvialis conditioning female organism |
| CN109430831A (en) * | 2018-10-31 | 2019-03-08 | 吉林省恒实传食品科技发展有限公司 | A kind of beautifying face and moistering lotion anti-aging health care's food formula and preparation method thereof |
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| CN110743004A (en) * | 2019-11-27 | 2020-02-04 | 天津活力达生物科技有限公司 | Astaxanthin direct drinking powder composition with whitening function and preparation method and application thereof |
| CN113797101A (en) * | 2020-06-11 | 2021-12-17 | 中国海洋大学 | Substrate film, composite film containing astaxanthin and high-molecular polysaccharide, preparation method and application |
| CN113797101B (en) * | 2020-06-11 | 2023-02-14 | 中国海洋大学 | Substrate film, composite film containing astaxanthin and high-molecular polysaccharide, preparation method and application |
| CN113208945A (en) * | 2021-05-18 | 2021-08-06 | 华熙生物科技股份有限公司 | Antioxidant composition, preparation method and application thereof in cosmetic composition |
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