CN105561208A - Traditional Chinese medicine unguent for treating cervical spondylotic radiculopathy - Google Patents

Traditional Chinese medicine unguent for treating cervical spondylotic radiculopathy Download PDF

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CN105561208A
CN105561208A CN201610095637.2A CN201610095637A CN105561208A CN 105561208 A CN105561208 A CN 105561208A CN 201610095637 A CN201610095637 A CN 201610095637A CN 105561208 A CN105561208 A CN 105561208A
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parts
rhizoma
plaster
filtrate
spondylotic radiculopathy
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Abstract

The invention discloses traditional Chinese medicine unguent for treating cervical spondylotic radiculopathy. The traditional Chinese medicine unguent is mainly prepared from, by weight, 8-14 parts of radix puerariae, 6-9 parts of herba lycopodii, 9-15 parts of dioscorea nipponica makino, 5-10 parts of rhizoma et radix notopterygii, 4-11 parts of sliced turmeric, 7-13 parts of zaocys, 6-15 parts of herba pyrolae, 6-9 parts of ramulus uncariae cum uncis, 1-5 parts of toddalia asiatualam, and 1-9 parts of squama manis. The traditional Chinese medicine unguent has effects of invigorating the circulation of blood for dysmenorrheal, relieving pains and dredging collaterals and has a very treatment effect on cervical spondylotic radiculopathy and complications thereof.

Description

The Chinese medicinal ointment for the treatment of cervical spondylotic radiculopathy
Divisional application, original applying number 2014101736898, applying date 2014.04.28, a kind of plaster for the treatment of cervical spondylotic radiculopathy of title and preparation method thereof.
Technical field
The invention discloses a kind of plaster for the treatment of cervical spondylotic radiculopathy and preparation method thereof, its dosage form is unguentum, the invention belongs to traditional Chinese medicine field.
Background technology
Cervical spondylosis, also known as cervical spine syndrome, is the general name of osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, Cervical disc extrusion, is a kind of illness changing into basis with degeneration pathology.Strain for a long time mainly due to cervical vertebra, hyperosteogeny, or prolapse of intervertebral disc, ligament thicken, and cause cervical vertebra spinal cord, nerve root or vertebral artery pressurized, occur a series of handicapped clinical syndrome.Show as intervertebral disc degradation itself and insecondary a series of pathological change thereof, as vertebra joint unstability, loosen; Nucleus pulposus or deviate from; Bony spur is formed; The spinal canal stenosis etc. of ligament plumpness and secondary, stimulates or has oppressed the tissues such as the nerve root of vicinity, spinal cord, vertebral artery and cervical region sympathetic nerve, cause series of symptoms and sign.
Cervical spondylotic radiculopathy is because of caused by one-sided or bilateral spinal nerve root irriate or pressurized, it shows as the sensation consistent with spinal nerve root areal area, motion and reflecting barrier, primary disease is more common, various non-operative treatment targetedly all has obvious curative effect, wherein especially continues (or interruption) traction, neck circumference braking with head and neck and correct bad position effective.
The clinical symptoms of cervical spondylosis is comparatively complicated.Mainly contain nape pain, upper myasthenia of limbs, point numb, lower limb are weak, difficulty in walking, dizziness, Nausea and vomiting, even blurred vision, tachycardia and dysphagia etc.Clinical symptoms and the diseased region of cervical spondylosis, involved and individual variation is organized to have certain relation.
The clinical manifestation of cervical spondylotic radiculopathy: 1. neck symptom: weight differs depending on causing the reason difference of root pressurized.Mainly because of person caused by Nucleus pulposus, how to be attentioned formula position with obvious cervical region pain, paravertebral muscles tenderness and cervical region because local hole nervi vertebralis directly stimulates, cervical spine or interspinal direct tenderness or kowtow pain and mostly be positive, and these performances are obvious especially with acute stage.As being the regression of pure uncovertebral joint and caused by hyperosteogeny person, then neck symptom is comparatively slight, even can without special discovery.2. a property pain: the most common, its scope is consistent with the spinal nerve root distributed areas that vertebra of getting involved saves.What accompany with root pain is other sensory disturbances of this nerve root areal area, wherein to go down etc. as common with numbness of the fingers, finger tip hyperesthesia and dermal sensation.3. a property muscular strength obstacle: the first pressurized person of former root is obviously, early stage hypermyotonia, but namely weakens and occur amyotrophy very soon.Its scope of getting involved also only is confined to the flesh group that this spinal nerve root is arranged.Be obvious at hand with large and small thenar and interosseus.4. tendon reflex changes: the reflex arc that spinal nerve root of namely getting involved participates in occurs abnormal.Early stage active, the intermediary and later stages then go down or disappear, should compared with offside during inspection.Simple root is got involved the pathologic reflex that do not have, and as with pathologic reflex, then represents that spinal cord is got involved simultaneously.
5. sign: the tractive test of all increase spinal nerve root tension force is mostly positive, especially acute stage and later root pressurized are main person.Cervical vertebra squeeze test positive is more common in and is deviate from based on Nucleus pulposus, vertebral pulp and case that vertebra joint is unstable, and is mostly the weak positive because of person caused by hook vertebra hypertrophy, because of person caused by Intraspinal Occupying Lesion, is mostly feminine gender.
In the invention of existing treatment cervical spondylotic radiculopathy, Authorization Notice No. Authorization Notice No. CN102526406B(application number 201210039492.6) Chinese patent disclose a kind of Chinese medicinal plaster for the treatment of cervical spondylotic radiculopathy and preparation method thereof: Radix Astragali 20-40 part, Radix Angelicae Sinensis 10-25 part, Herba Epimedii 15-30 part, Colla cornus cervi 5-25 part, Radix Paeoniae Rubra 6-20 part, Ramulus Cinnamomi 6-20 part, Sanguis Draxonis 3-20 part, Herba Lycopodii 6-20 part, Semen Sinapis 6-20 part, Radix Notoginseng 6-20 part, Flos Carthami 6-20 part, Olibanum 6-20 part, Borneolum Syntheticum 3-13 part.Authorization Notice No. CN101912539B(application number 201010257525.5) Chinese patent disclose a kind of Chinese medicine composition being used for the treatment of cervical spondylotic radiculopathy and preparation method thereof, formula and part by weight are A, take 10-50 weight portion Radix Angelicae Sinensis, 10-50 weight portion Rhizoma Chuanxiong and 6-35 weight portion Cortex Cinnamomi, 1-3 hour is soaked after mixing, then distillating extracting oil at temperature 98-100 DEG C, the volatile oil beta-cyclodextrin inclusion compound of collection, at temperature 50-60 DEG C, stir 1-3 hour, place cooling, after cold drying, be ground into fine powder, distillation remaining aqueous solution and medicinal residues stand-by, B, respectively 10-50 weight portion Radix Notoginseng and 10-50 weight portion Rhizoma Gastrodiae powder are broken into fine powder, then they are mixed, soak 1-3 hour again, then 1-2 hour is decocted, filter after cooling and obtain filtrate and medicinal residues, these medicinal residues with in steps A) medicinal residues that obtain merge, decoct with water 1-3 time after mixing with 10-50 weight portion Flos Carthami again, each 0.5-3 hour, filter, this merging filtrate and the filtrate obtained above, steps A) the distillation remaining aqueous solution that obtains merges, carry out concentrating under reduced pressure again until at temperature 50-60 DEG C the clear paste of relative density 1.10-1.30, then drying under reduced pressure, be ground into fine powder, add 3-16 weight portion artificial Calculus Bovis, steps A) obtain Benexate Hydrochloride and dextrin, mix homogeneously.
Summary of the invention
For existing current treatment status, an object of the present invention is to provide a kind of plaster for the treatment of cervical spondylotic radiculopathy, not only there is Chinese medicine composition of the present invention there is blood circulation promoting and blood stasis dispelling, warming the meridian understand things pain-stopping, also can be used for cervical spondylotic radiculopathy syndrome of static blood blocking collaterals, disease sees that neck and shoulder part is stiff, pain, and ipsilateral upper limb alters pain etc.
Another object of the present invention is just to provide the preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of plaster for the treatment of cervical spondylotic radiculopathy, take off the primary raw material stating weight proportion to be prepared from: Radix Puerariae 8-14 part, Herba Lycopodii 6-9 part, Rhizoma Dioscoreae Nipponicae 9-15 part, Rhizoma Et Radix Notopterygii 5-10 part, Rhizoma Wenyujin Concisum 4-11 part, Zaocys 7-13 part, Herba Pyrolae 6-15 part, Ramulus Uncariae Cum Uncis 6-9 part, Sedum aizoon L. 1-5 part, Squama Manis 1-9 part.
The plaster of above-mentioned treatment cervical spondylotic radiculopathy, preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Radix Puerariae 10-12 part, Herba Lycopodii 7-8 part, Rhizoma Dioscoreae Nipponicae 11-13 part, Rhizoma Et Radix Notopterygii 6-8 part, Rhizoma Wenyujin Concisum 6-9 part, Zaocys 8-10 part, Herba Pyrolae 10-12 part, Ramulus Uncariae Cum Uncis 7-8 part, Sedum aizoon L. 2-4 part, Squama Manis 4-6 part.
The plaster of the above treatment cervical spondylotic radiculopathy, better preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Radix Puerariae 11 parts, Herba Lycopodii 7.5 parts, Rhizoma Dioscoreae Nipponicae 12 parts, Rhizoma Et Radix Notopterygii 7 parts, Rhizoma Wenyujin Concisum 8 parts, Zaocys 9 parts, Herba Pyrolae 11 parts, Ramulus Uncariae Cum Uncis 7.5 parts, Sedum aizoon L. 3 parts, Squama Manis 5 parts.
According to the preparation method of the plaster of arbitrary described treatment cervical spondylotic radiculopathy above, step is as follows:
1. Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and leaves standstill 1-10 days, and filtration, obtains filtrate and filtering residue is for subsequent use;
2. step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 30-50 minute, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 6-12 hour, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 60 DEG C-80 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 1-10g to spread upon in adhesive plaster or other substrate, make plaster.
According to above-mentioned preparation method, preferred scheme is: 1. step leaves standstill 3-8 days (preferably 5 days).
According to above-mentioned preparation method, preferred scheme is: 2. step decocts to 35-45 minute (preferably 40 minutes).
According to above-mentioned preparation method, preferred scheme is: 3. step leaves standstill 7-10 hour (preferably 9 hours).
According to above-mentioned preparation method, preferred scheme is: 4. step is closed fire and be cooled to 65 DEG C-75 DEG C (preferably 70 DEG C).
According to above-mentioned preparation method, preferred scheme is: the weight ratio of step 4. vegetable oil, Colophonium, white vaseline and distillate is 0.8:1.5:1.5:0.8.
According to the application of plaster when the medicine of preparation treatment cervical spondylotic myelopathy, cervical muscle myelopathy of the treatment cervical spondylotic radiculopathy above described in any one.
Best using method: be the therapeutic effect making the present invention reach best, plaster is directly affixed on uncomfortable cervical vertebra place, gently seals about 1 minute after subsides with palm, and pasting and wear 12 hours, every day 1 time, 10 days is a course for the treatment of.
Treat a plaster for cervical spondylotic radiculopathy, the pharmacological effect of each raw material is respectively:
Radix Puerariae: sweet in the mouth, pungent, cool in nature.Return spleen, stomach warp.Effect: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Cure mainly: fever caused by exogenous pathogens is had a headache, stiff nape and back is thirsty, quenches one's thirst, measles without adequate eruption, hematodiarrhoea.
Herba Lycopodii: Herba Lycopodii, stolon is in carefully cylindrical, and slightly bending, length can reach 2m, diameter 1 ~ 3mm, has yellow-white radicula under it.Erect stern makes two dichotomies.On Ye Misheng stem, helical arrangement, shrinkage bends, linear or aciculiform, long 3 ~ 5mm, and yellow green is extremely fallow, without hair, tip aristiform, Quan Yuan, easily cataclasm.Matter is soft, and section skin zone is light yellow, woody part off-white color.Odorless, lightly seasoned.Toil temperature, enters Liver Channel.Expelling wind and cold. dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle.External is controlled osteopatia sprain and is swollen and ache.
Rhizoma Dioscoreae Nipponicae: return liver, kidney, lung meridian, warm in nature, sweet in the mouth, hardship.Relaxing muscles and tendons to promote blood circulation, relieving cough and resolving phlegm, wind-expelling pain-stopping.For lumbago and skelalgia, rheumatalgia, rheumatic arthritis, muscles and bones numbness, Kaschin-Beck disease, traumatic injury, sprain one's back, cough pant, tracheitis, bronchitis.
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature.Return bladder, kidney channel.Effect: cold expelling, dispels the wind, dehumidifying, pain relieving.Cure mainly: anemofrigid cold is had a headache, rheumatic arthralgia, aching pain in should and back.
Rhizoma Wenyujin Concisum: acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.Effect: removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.Cure mainly: amenorrhea due to stagnation of blood, menalgia, the twinge of the breast side of body, rheumatic arthralgia, shoulder arm pain, injury from falling down.
Zaocys: sweet in the mouth, property is put down.Return Liver Channel.Effect: dispel the wind, dredging collateral, relieving convulsion.Cure mainly: rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Herba Pyrolae: sweet in the mouth, hardship, warm in nature.Return liver, kidney channel.Effect: wind-damp dispelling, bone and muscle strengthening, hemostasis.Cure mainly: rheumatic arthralgia, weakness of the waist and knees, menorrhagia, chronic cough due to asthenia of viscera.
Ramulus Uncariae Cum Uncis: Ramulus Uncariae Cum Uncis sweet in the mouth, micro-hardship, cold nature; Return liver, pericardium channel; Matter heavily fortified point is dived and is fallen, and has heat clearing away suppressing the hyperactive liver, effect of relieving spasm by subduing liver-wind, and cure mainly liver-fire superinverse headache conjunctival congestion, excessive rising of liver-YANG is had a dizzy spell, intenseness of heat wind symptom infantile convulsion, infantile convulsion, night cry, eclamposia, paralysis due to windstroke, and podomere contraction is anxious.
Sedum aizoon L.: the upright draft of perennial root, height about 15 centimetres.Root conico-acuminate.Basal leaf has long handle, the micro-band blush of light green, and the wealthy heart of blade or sub-circular, long 1 ~ 3 centimetre, wide 2 ~ 4.8 centimetres, there is shallow round cognate at edge.Spend single leave axil, rose-pink color bands is yellow.Capsule.[nature and flavor] pungent fiber crops, temperature.[function cures mainly] promoting the flow of QI in the collateral by warming the meridian, stopping bleeding and knitting the fractured bone.External is controlled open fracture, is controlled traumatic hemorrhage.
Squama Manis: salty in the mouth, cold nature.Return liver, stomach warp.Effect: stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral.Cure mainly: amenorrhea and mass in the abdomen, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
Colophonium, vegetable oil, white vaseline are excipient, play the effect of mediation figuration.
Plaster is the large dosage form-ball of Chinese medicine five, loose, one of cream, pellet, soup.Ancient doctor's speech is said: " plaster can be cured the disease, and not different from decoction, does in the proper way with it, and it rings vertical answering." prescription of the present invention all selects Xin Xiang to walk to go here and there extremely strong tying-in medicine, medicine directly infiltrates through skin, by interior transmission from one channel to another network, plays disperse blood stasis and dredge collateral, the effect that pain relieving is stimulated the menstrual flow.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 one kinds treats the plaster of cervical spondylotic radiculopathy, takes off the primary raw material stating weight proportion and is prepared from (getting 15g for every part): Radix Puerariae 8 parts, Herba Lycopodii 6 parts, Rhizoma Dioscoreae Nipponicae 9 parts, Rhizoma Et Radix Notopterygii 5 parts, Rhizoma Wenyujin Concisum 4 parts, Zaocys 7 parts, Herba Pyrolae 6 parts, Ramulus Uncariae Cum Uncis 6 parts, Sedum aizoon L. 1 part, Squama Manis 1 part.
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and leaves standstill 1 day, and filtration, obtains filtrate and filtering residue is for subsequent use;
2. step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 30 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 6 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 60 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 1g to spread upon in adhesive plaster or other substrate, make plaster.
Typical case one poplar XX, man, 40 years old, Jinan, Shandong Province personage, the workman of certain factory.Nearest half a year cervical region pain, paravertebral muscles tenderness, and lower limb have feeling of numbness, stiffly to shake, do not have unable on foot, think it is that work is tired out at the beginning, do not take notice of very much yet, but in nearest one month, cervical vertebra pain is severe, directly impact sleep and work, check to Jinan large hospital under the accompanying of layman, check and find patient's restriction of neck motion, the pain increased in layback, and cervical region tenderness is obvious, there is trapezoidal change in x-ray plain film vertebra joint, is diagnosed as: cervical spondylotic radiculopathy.The embodiment of the present invention 1 gained plaster is brought into use under the suggestion of doctor.
Use the embodiment of the present invention 1 gained plaster, once a day, each subsides wears 12 hours in cervical pain place, within 10 days, is a course for the treatment of.Use 10 days, pain is obviously alleviated, and numb limbs and tense tendons sense makes moderate progress.Use 20 days, pain disappears substantially, and feeling of numbness is obviously alleviated, and has strength on foot.Continue use 10 days, patient's self-induction is fully recovered.
Embodiment 2 one kinds treats the plaster of cervical spondylotic radiculopathy, take off the primary raw material stating weight proportion to be prepared from (getting 10g for every part): Radix Puerariae 14 parts, Herba Lycopodii 9 parts, Rhizoma Dioscoreae Nipponicae 15 parts, Rhizoma Et Radix Notopterygii 10 parts, Rhizoma Wenyujin Concisum 11 parts, Zaocys 13 parts, Herba Pyrolae 15 parts, Ramulus Uncariae Cum Uncis 9 parts, Sedum aizoon L. 5 parts, Squama Manis 9 parts.
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and leaves standstill 10 days, and filtration, obtains filtrate and filtering residue is for subsequent use;
2. step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 45 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 12 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 80 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 10g to spread upon in adhesive plaster or other substrate, make plaster.
Typical case two Cao XX, female, 52 years old, Weifang, Shandong personage.During last summer, accidentally drench with rain, conscious left side neck root after suffering from cold, shoulder and left upper arm pain, and extremity have slight feeling of numbness, originally do not take notice of, think and just suffered from cold, but before 1 month, there is urgent micturition in patient, frequent micturition, the symptom of constipation, child sees that the uncomfortable just band mother of mother goes to hospital to check, check and find patient's Wry Neck, cervical region is tilted to the right limited, when cervical region rotates to the left, the pain increased, cervical region with do scapula position and all have obvious tenderness sense, the slight lateral bending of X sheet display cervical flexure, be diagnosed as: cervical spondylotic radiculopathy, because patient does not think the money that cost sons and daughters are too many, doctor just suggestion uses embodiment 2 gained plaster.
Use the embodiment of the present invention 2 gained plaster, once a day, each subsides wears 12 hours, and cervical region and scapular region respectively paste one, within 10 days, are a course for the treatment of.Use 5 days, paste and wear the sensation that there is heating at position, feel well.Use 20 days, pain alleviates.Use 30 days, when noting posture and rest, substantially can avoid the generation of cervical pain symptom, omoplate place pain disappears completely, and cervical region can swing comparatively normally, and defecation is normal, and had no side effect between the operating period generation.
Embodiment 3 one kinds treats the plaster of cervical spondylotic radiculopathy, take off the primary raw material stating weight proportion to be prepared from (getting 20g for every part): Radix Puerariae 10 parts, Herba Lycopodii 7 parts, Rhizoma Dioscoreae Nipponicae 11 parts, Rhizoma Et Radix Notopterygii 6 parts, Rhizoma Wenyujin Concisum 6 parts, Zaocys 8 parts, Herba Pyrolae 10 parts, Ramulus Uncariae Cum Uncis 7 parts, Sedum aizoon L. 2 parts, Squama Manis 4 parts.
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and leaves standstill 3 days, and filtration, obtains filtrate and filtering residue is for subsequent use;
2. step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 35 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 7 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 65 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 3g to spread upon in adhesive plaster or other substrate, make plaster.
Typical case three XX, man, 60 years old, people from Qingzhou, Weifang City, peasant.Cervical spondylotic radiculopathy history 1 year, cervicodynia is uncomfortable in chest, and with the symptom of blurred vision, nearest right arm sensation grips unable, and health has constrained sense, couches night and all feels uncomfortable, cannot fall asleep and cause lethargy.Check and find patient's instability of gait, hands grasping power is all not high, and right arm situation is even more serious, and compression of spinal cord is comparatively obvious, seeks medical advice everywhere, all to no effect, sees plaster of the present invention unintentionally on newspaper, have the attitude of trying in arms and bought 2 courses for the treatment of.
Use the embodiment of the present invention 3 gained plaster, once a day, each subsides wears 12 hours, and cervical region and right arm scapular region respectively paste one, within 10 days, are a course for the treatment of.Use 10 days, nighttime sleep has clear improvement, and can fall asleep.Use 20 days, both hands have obvious strength high, and mental attitude is taken on a new look to some extent, and pain symptom alleviates.Use 30 days, pain obviously alleviates, and mental restoration is good, and vision is also recovered to some extent.Use 50 days, other malaise symptoms disappear substantially, and patient's self-induction is fully recovered.
1, embodiment 4 one kinds treats the plaster of cervical spondylotic radiculopathy, take off the primary raw material stating weight proportion to be prepared from (getting 25g for every part): Radix Puerariae 12 parts, Herba Lycopodii 8 parts, Rhizoma Dioscoreae Nipponicae 13 parts, Rhizoma Et Radix Notopterygii 8 parts, Rhizoma Wenyujin Concisum 9 parts, Zaocys 10 parts, Herba Pyrolae 12 parts, Ramulus Uncariae Cum Uncis 8 parts, Sedum aizoon L. 4 parts, Squama Manis 6 parts.
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and leaves standstill 8 days, and filtration, obtains filtrate and filtering residue is for subsequent use;
2. step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 45 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 10 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 75 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 8g to spread upon in adhesive plaster or other substrate, make plaster.
Embodiment 5 one kinds treats the plaster of cervical spondylotic radiculopathy, take off the primary raw material stating weight proportion to be prepared from (getting 30g for every part): Radix Puerariae 11 parts, Herba Lycopodii 7.5 parts, Rhizoma Dioscoreae Nipponicae 12 parts, Rhizoma Et Radix Notopterygii 7 parts, Rhizoma Wenyujin Concisum 8 parts, Zaocys 9 parts, Herba Pyrolae 11 parts, Ramulus Uncariae Cum Uncis 7.5 parts, Sedum aizoon L. 3 parts, Squama Manis 5 parts.
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and leaves standstill 5 days, and filtration, obtains filtrate and filtering residue is for subsequent use;
2. step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 40 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 9 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 70 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 5g to spread upon in adhesive plaster or other substrate, make plaster.
Experimental example is in order to verify the curative effect of the present invention to cervical spondylotic radiculopathy, and chosen two or more person 200 people of cervical spondylotic radiculopathy symptom, the mean age is 40 years old, two groups are divided into according to the state of an illness, experimental group and matched group, often organize 100 people, basically identical to ensure two groups of situations.Experimental group uses embodiment 5 gained plaster, once a day, each subsides wear 12 hours, it within 10 days, is a course for the treatment of, matched group uses the Chinese medicine of other oral medication cervical spondylotic radiculopathyes, observes 30 days time limits, first within 1 day, comprehensively checks the symptom of patient before experiment, regularly check inquiry patient body situation and impression during experiment, and make a record.
1, carry out record to the curative effect of two groups of medicines, result is as following table 1.(criterion, effectively: the malaise symptoms caused by cervical spondylotic radiculopathy has clear improvement; Invalid: the malaise symptoms caused by cervical spondylotic radiculopathy is unchanged.)
Table 1:
Analyze: as can be seen from Table 1, the present invention is 99% to the effective percentage of cervical spondylotic radiculopathy, exceeds matched group 19%, Be very effective.
2, carry out record to two groups of patient's applied mental changes, result is as following table 2.
Table 2:
Analyze: as can be seen from Table 2, medicament mode of the present invention is more easily approved by patient, and major part represents per capita, Long-term taking medicine easily causes mental pressure, and obviously can affect appetite, external used medicine is favored by more people on therapeutic modality, is also more easy to accept and adhere to long-term treatment.Through finding out the analysis of many group experimental datas, plaster of the present invention is obvious for cervical spondylotic radiculopathy curative effect, and total effective rate is up to 99%, and without any side effects, can reach the effect of pain-alleviating and network vessel-freeing comparatively rapidly.On therapeutic modality, the present invention is also easier to, by patient's recognition and acceptance, to lay a good foundation for later treatment.Chinese medicine composition of the present invention achieves significant effect, stable curative effect in treatment cervical spondylotic radiculopathy, has no side effect, is suitable for long-term taking.

Claims (2)

1. treat a plaster for cervical spondylotic radiculopathy, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Radix Puerariae 12 parts, Herba Lycopodii 8 parts, Rhizoma Dioscoreae Nipponicae 13 parts, Rhizoma Et Radix Notopterygii 8 parts, Rhizoma Wenyujin Concisum 9 parts, Zaocys 10 parts, Herba Pyrolae 12 parts, Ramulus Uncariae Cum Uncis 8 parts, Sedum aizoon L. 4 parts, Squama Manis 6 parts.
2. treat the preparation method of the plaster of cervical spondylotic radiculopathy, it is characterized in that,
1. Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and leaves standstill 8 days, and filtration, obtains filtrate and filtering residue is for subsequent use;
2. step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 45 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 10 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 75 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 8g to spread upon in adhesive plaster or other substrate, make plaster.
CN201610095637.2A 2014-04-28 2014-04-28 Traditional Chinese medicine unguent for treating cervical spondylotic radiculopathy Withdrawn CN105561208A (en)

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Application publication date: 20160511

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